Search Results
Results 751 - 800 of 1588
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Ono Satoshi - - 2007
The purpose of this study was to evaluate the effect of sivelestat sodium hydrate, a selective inhibitor of neutrophil elastase in the systemic inflammatory response, pulmonary function, and the postoperative clinical course following esophagectomy. Patients with hypoxia associated with surgical stress in the intensive care unit (ICU) immediately after an ...
Lukas Jindrich - - 2007
OBJECTIVE: The present prospective randomized trial compared surgical tracheostomy (ST) and percutaneous dilatational tracheostomy (PDT) in intensive care unit (ICU) patients in terms of outcomes and complications. METHODS: Between January 2003 and December 2005 tracheostomies were performed on critically ill ICU patients in Medical Faculty Hospital in Prague, with a ...
Woodfield John C - - 2007
BACKGROUND: The ability to predict who will develop perioperative complications remains difficult because the etiology of adverse events is multifactorial. This study examines the preoperative and postoperative ability of the surgeon to predict complications and assesses the significance of a change in prediction. METHODS: This was a prospective study of ...
Acharya S P - - 2007
BACKGROUND: Various scoring systems have been developed to prioritize patient admission and management in ICU. The objective of this prospective, observational cohort study was to evaluate application of one such system, the Sequential Organ Failure Assessment (SOFA) Score in predicting outcome in ICU patients with SIRS. PATIENTS AND METHODS: Fifty ...
Ryan Aoife M - - 2007
OBJECTIVE: Changes in serum albumin may reflect systemic immunoinflammation and hypermetabolism in response to insults such as trauma and sepsis. Esophagectomy is associated with a major metabolic stress, and the aim of this study was to determine if the absolute albumin level on the first postoperative day was of value ...
Stawicki S Peter - - 2008
OBJECTIVE: A damage control (DC) approach was developed to improve survival in severely injured trauma patients. The role of DC in acute surgery (AS) patients who are critically ill, as a result of sepsis or overwhelming haemorrhage continues to evolve. The goal of this study was to assess morbidity and ...
Dhar Rajat - - 2008
One third of patients with Guillain-Barré syndrome (GBS) require admission to the intensive care unit (ICU), associated with significant risk of morbidity, mortality, and incomplete recovery. METHODS: 76 adult patients with GBS admitted to the ICU at a regional referral center over a 20-year period were studied. We determined the ...
Scala Raffaele - - 2007
OBJECTIVE: We recently reported a high success rate using noninvasive positive pressure ventilation (NPPV) to treat COPD exacerbations with hypercapnic encephalopathy. This study compared the hospital outcomes of NPPV vs. conventional mechanical ventilation (CMV) in COPD exacerbations with moderate to severe hypercapnic encephalopathy, defined by a Kelly score of 3 ...
Matić Ivo - - 2007
Our aim was to evaluate the influence of static pulmonary compliance (Cst) on the choice of Mechanical Ventilation(MV) method and treatment outcome. A prospective, randomized trial conducted out at the multidisciplinary Intensive Care Unit (ICU) included 387 patients, randomized in two groups: noninvasive MV group and invasive MV group. Furthermore, ...
Yende Sachin - - 2007
Long-term mortality following severe sepsis is high, and fewer than half of patients who experience severe sepsis are alive at 1 year. Mechanisms underlying increased long-term mortality remain poorly understood. Animal and human studies suggest that abnormalities of the innate immune system may contribute to increased long-term mortality. This review ...
Bosma Karen J - - 2007
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a life-threatening form of respiratory failure that affects a heterogeneous population of critically ill patients. Although overall mortality appears to be decreasing in recent years due to improvements in supportive care, there are presently no proven, effective pharmacological therapies to treat ARDS ...
Brahmi Nozha - - 2007
Methanol poisoning continues to be a public health problem in Tunisia in spite of the different legislative measures. We report a series of 16 cases of methanol poisoning admitted to our Intensive Care Unit between December 2003 and April 2004. The patients' median age was 21.5 years (range 16 to ...
Annane Djillali - - 2007
BACKGROUND: International guidelines for management of septic shock recommend that dopamine or norepinephrine are preferable to epinephrine. However, no large comparative trial has yet been done. We aimed to compare the efficacy and safety of norepinephrine plus dobutamine (whenever needed) with those of epinephrine alone in septic shock. METHODS: This ...
Ginz H F - - 2008
BACKGROUND: This study's main purpose was to test the feasibility of employing a non-invasive-stimulated muscle force assessment approach in long-term critically ill patients. METHODS: A case series was performed over a 4-year period in the intensive care unit (ICU). Of the 25 patients initially recruited, eight patients required long-time mechanical ...
Tasouli Androniki - - 2007
OBJECTIVE: Levosimendan is a promising new inotrope. We investigate the proper time for its infusion during or after open-heart surgery to avoid complications related with low-output syndrome and high dosage of inotropes. METHODS: Forty-five consecutive patients were randomised to receive levosimendan in addition to the conventional therapy, its infusion starting ...
Liu Hui - - 2007
The aim of the present study was to identify early risk factors for prolonged mechanical ventilation (PMV) in chronic obstructive pulmonary disease (COPD) patients admitted to respiratory intensive care units (RICU) for acute hypercapnic respiratory failure. PMV was defined as invasive ventilation lasting longer than 7 days. Between January 1, ...
Heringlake Matthias - - 2007
OBJECTIVE: The modified algorithm for the non-invasive determination of cardiac output (CO) by electrical bioimpedance-electrical velocimetry (EV)-has been reported to give reliable results in comparison with echocardiography and pulmonary arterial thermodilution (PA-TD) in patients either before or after cardiac surgery. The present study was designed to determine whether EV-CO measurements ...
Reddy Shekar L C - - 2007
BACKGROUND: The aim of this study was to develop a multivariate risk prediction model for prolonged ventilation after adult cardiac surgery. METHODS: This is a retrospective analysis of prospectively collected data on 12,662 consecutive patients undergoing adult cardiac surgery between April 1997 and March 2005. Data were randomly split into ...
Terra Ricardo Mingarini - - 2007
BACKGROUND: Tracheostomy is electively performed in critically ill patients requiring prolonged respiratory support. The risk of transporting, the increasing associated cost and operative room schedule are some of the obstacles for wider acceptance of this procedure. The use of rigid selection criteria exclude many patients who would benefit of this ...
Novotny Alexander - - 2007
BACKGROUND: To develop strategies for the prediction of sepsis outcome systemic procalcitonin (PCT) levels were correlated with various clinical parameters. METHODS: PCT levels and Acute Physiology and Chronic Health Evaluation (APACHE) II scores were assessed on the day of sepsis diagnosis in a large series (n = 160) of patients ...
Bilotta Federico - - 2007
It is unclear if avoiding hyperglycemia during intensive care after acute brain injury improves morbidity, mortality, and neurologic outcome. This prospective randomized trial tested whether intensive insulin therapy affected infection rates, vasospasm, mortality, or long-term neurologic outcome in subarachnoid hemorrhage patients during their intensive care unit (ICU) stay. Comparison was ...
Villar Jesús - - 2007
RATIONALE: Current American-European Consensus Conference definitions for acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are inadequate for inclusion into clinical trials due to the lack of standardization for measuring the oxygenation defect. OBJECTIVES: We questioned whether an early assessment of oxygenation on specific ventilator settings would identify ...
Vallés J - - 2007
OBJECTIVE: To determine the impact of ventilator-associated pneumonia (VAP) on ICU mortality, and whether it is related to time of onset of pneumonia. DESIGN: Prospective cohort study. SETTING: 16-bed medical-surgical ICU at a university-affiliated hospital. PATIENTS AND MEASUREMENTS: From 2002 to 2003, we recorded patients receiving mechanical ventilation for > ...
Simon Caterina - - 2007
BACKGROUND: Preoperative renal dysfunction is an important risk factor in cardiac surgery. Thus, the association between creatinine clearance (ClCr) and mechanical ventilation time and ICU length of stay, independent of other established preoperative risk indicators, was analyzed. METHODS: In our study, 156 consecutive patients underwent open-heart surgery at the Department ...
Cheng Wei-Erh - - 2007
OBJECTIVE: To determine whether urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG), an in vivo parameter of oxidative stress, is correlated with the outcome of critically septic patients. DESIGN AND SETTING: Clinical outcome study in an adult medical ICU. PATIENTS: Eighty-five consecutive septic patients: 59 men and 26 women. MEASUREMENTS AND RESULTS: Urinary 8-OHdG was ...
Mentzelopoulos Spyros D - - 2007
OBJECTIVE: We present our experience with five cases of pandrug-resistant Pseudomonas aeruginosa ventilator-associated pneumonia (VAP) and analysis of risk factors. DESIGN AND SETTING: Case-control study in a 15-bed intensive care unit (ICU). PATIENTS AND PARTICIPANTS: The study included 5 cases and 20 controls. Each case patient was matched to four ...
Ahmed Nasim - - 2007
BACKGROUND AND PURPOSE: A majority of patients with severe traumatic brain injury (TBI) need ventilatory support and require endotracheal intubation. There has been substantial debate regarding the timing of tracheostomy. We reviewed our data to determine the impact of early tracheostomy on our resources. STUDY DESIGN: Retrospective review of a ...
Yuan Nanci - - 2007
Progressive respiratory muscle weakness with bulbar involvement is the main cause of morbidity and mortality in type I and severe type II spinal muscular atrophy. Noninvasive positive pressure ventilation techniques coupled with laparoscopic gastrointestinal procedures may allow for improved morbidity and mortality. The authors present a series of 7 spinal ...
Otsuka Yuichi - - 2007
BACKGROUND/AIMS: In order to predict morbidity after gastrectomy for gastric cancer in aged patients, the Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity (POSSUM) scoring system was applied. METHODOLOGY: A total of 123 patients who had gastrectomies for gastric cancer at the age of 75 or ...
HIDA, Seiji
Proinflammatory cytokines are thought to play important roles in the pathophysiology of encephalopathy in patients with fulminant hepatitis (FH). The aim of this study was to investigate the association between circulating proinflammatory cytokines and the severity of encephalopathy in FH patients. The study included 19 patients with FH who were ...
Bach John R - - 2007
OBJECTIVES: To report long-term survival of spinal muscular atrophy type 1 (SMA 1) and consequences on speech and ventilator dependence as a function of mode of ventilator use. DESIGN: A retrospective chart review of 106 consecutively referred SMA 1 patients, the 92 most severe of which were considered in three ...
Fischler L - - 2007
BACKGROUND AND OBJECTIVE: Mortality prediction systems have been calculated and validated from large mixed ICU populations. However, in daily practice it is often more important to know how a model performs in a patient subgroup at a specific ICU. Thus, we assessed the performance of three mortality prediction models in ...
Belii A - - 2007
OBJECTIVE: The aim of this study was to test the efficacy of a respiratory weaning algorithm (WA) in postoperative cardiac surgery patients. This algorithm was made simple enough to be implemented in medium-end ventilator software. PATIENTS: Twenty consecutive postoperative patients who underwent scheduled cardiac surgery with normal postoperative haemodynamic and ...
Meduri G Umberto - - 2007
OBJECTIVE: To determine the effects of low-dose prolonged methylprednisolone infusion on lung function in patients with early severe ARDS. DESIGN: Randomized, double-blind, placebo-controlled trial. SETTING: ICUs of five hospitals in Memphis. PARTICIPANTS: Ninety-one patients with severe early ARDS (</= 72 h), 66% with sepsis. INTERVENTIONS: Patients were randomized (2:1 fashion) ...
Couto Renato C - - 2007
Late-onset sepsis (LOS) (i.e., sepsis in a neonate after 72 hours of life) is associated with high mortality and significantly prolonged antibiotic exposure and hospital stay in neonates admitted to intensive care units (ICU). In this study, we assessed the reliability of serum C-reactive protein (CRP) as a determinant of ...
François Bruno - - 2007
BACKGROUND: The efficacy of corticosteroids in reducing the incidence of postextubation laryngeal oedema is controversial. We aimed to test our hypothesis that methylprednisolone started 12 h before a planned extubation could prevent postextubation laryngeal oedema. METHODS: We did a placebo-controlled, double-blind multicentre trial in 761 adults in intensive-care units. Patients ...
Teixeira P J Z - - 2007
Initial antibiotic therapy is an important determinant of clinical outcomes in ventilator-associated pneumonia (VAP). Several studies have investigated this issue, with conflicting results. This study investigated risk factors of inadequate empirical antimicrobial therapy and its impact on outcomes for patients with a clinical diagnosis of VAP. The primary outcome was ...
Svoboda Petr - - 2007
BACKGROUND/AIMS: In surgical sepsis, the rapid identification of source of infection at an early stage after surgery or serious trauma is crucial for favorable outcome. The discrimination between local and generalized infection is critical for correct treatment. METHODOLOGY: In a randomized, controlled, single-centre study we investigated 72 patients with severe ...
Burkhardt O - - 2007
OBJECTIVE: This study was designed to search for risk factors predicting mortality of patients with Wegener's granulomatosis (WG) treated on the intensive care unit (ICU). METHODS: Seventeen patients admitted to the ICU of an University Hospital for an acute illness related to WG were analysed retrospectively over 4 years. A ...
Cai Hongwei - - 2007
STUDY OBJECTIVE: To determine whether low tidal ventilation in patients without lung injury results in an increase in the amount of atelectasis and a further impairment of gas exchange during general anesthesia. DESIGN: Randomized, single-blind study. SETTING: University hospital. PATIENTS: 16 adult, ASA physical status I and II patients, who ...
Kinnunen T - - 2007
BACKGROUND: Hospitalisation periods for the acute exacerbation phase of COPD are a strain on health facilities and entail high rates of hospital mortality. The aim of this study was to ascertain the characteristics of treatment periods resulting in death and the risk factors involved on the basis of treatment registers ...
Leung Randal - - 2007
OBJECTIVE: To determine the change in the statewide incidence of severe acquired subglottic stenosis (SGS) in newborns over the past decade. METHODS: Multicenter, statewide retrospective study of all patients under the age of 12 months who were diagnosed with acquired SGS that required surgical intervention by anterior cricoid split (ACS) ...
Zuschneid I - - 2007
OBJECTIVE: To investigate trends in ventilator-associated pneumonia (VAP) rates during participation in the German nosocomial infection surveillance system (Krankenhaus-Infektions-Surveillance-System [KISS]). METHODS: A total of 71 ICUs that began participating in KISS in 1999 or later and continued participation for at least 36 months were selected. Beginning with the first month ...
Rimachi R - - 2007
There are few data on long-term outcomes in mixed groups of intensive care unit (ICU) patients with prolonged stays. We evaluated the relationship between length of stay in the ICU and long-term outcome in all patients admitted to our 31-bed department of medico-surgical intensive care over a one-year period who ...
Teoh D C A - - 2007
A 52-year-old patient with Klippel-Feil syndrome was scheduled for elective C1 dorsal laminectomy and occipito-cervical stabilisation under general anaesthesia. Preoperatively she had bulbar symptoms and a history of recurrent aspiration pneumonia, but no evidence of cardiovascular disease. When she was turned prone she developed persistent tachycardia, hypotension and ST segment ...
Hersch Moshe - - 2007
BACKGROUND: In some hospitals, patients are mechanically ventilated on the wards in addition to the intensive care unit (ICU) because of the shortage of ICU beds. OBJECTIVE: The aim of the study was to compare the outcome and ventilatory management of medical patients mechanically ventilated on the medical wards and ...
Heimrath Olivier P - - 2007
BACKGROUND: The primary objective of this study was to determine the long-term outcomes of all patients requiring prolonged intensive care unit (ICU) stay following coronary bypass surgery (CABG) surgery. METHODS: All patients undergoing CABG surgery between 1998 and 2002 were reviewed. Prolonged ICU stay was defined as more than 48 ...
Karlsson Sari - - 2007
OBJECTIVE: To determine the incidence and outcome of severe sepsis in the adult Finnish population and to evaluate how treatment guidelines in severe sepsis are applied in clinical practice. STUDY DESIGN: A prospective study in 24 closed multidisciplinary ICUs in 21 hospitals (4 university and 17 tertiary hospitals) in Finland. ...
Yurtseven N - - 2007
BACKGROUND AND OBJECTIVE: Tracheostomy is one of the most common procedures in intensive care units worldwide. In this study we aimed to compare three different tracheostomy techniques with respect to duration of procedure and complications. METHODS: One hundred and thirty patients requiring endotracheal intubation for more than 10 days due ...
Stawicki Peter
<b>Purpose:</b> The esophageal Doppler monitoring (EDM) has emerged as an alternative to the pulmonary artery catheter (PAC). The purpose of this study is to better define its role in the ICU. <b> Materials and Methods:</b> Retrospective review of Hemosonic™ 100 EDM probe use between 2003 and 2005. Patient- and EDM-related ...
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