Search Results
Results 701 - 750 of 1654
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Schneider Christian P - - 2009
BACKGROUND: Acute mortality of unselected critically ill patients has improved during the last 15 years. Whether these benefits also affect survival of critically ill patients with secondary peritonitis is unclear as is the relevance of specific prognostic factors, such as source control. METHODS: We performed a retrospective analysis of data ...
Ramku E M D - - 2009
BACKGROUND: To assess clinical features and treatment of children's tracheotomy seen in ENT/Head and Neck Surgery Clinic and Intensive Care Unit at the University Clinical Centre, Prishtina Kosovo. METHOD: A systematic review of the medical records of all patients admitted to the ENT clinic and intensive care unit having tracheotomy ...
Reade Michael C - - 2009
INTRODUCTION: Agitated delirium is common in patients undergoing mechanical ventilation, and is often treated with haloperidol despite concerns about safety and efficacy. Use of conventional sedatives to control agitation can preclude extubation. Dexmedetomidine, a novel sedative and anxiolytic agent, may have particular utility in these patients. We sought to compare ...
Hodder Richard V - - 2009
INTRODUCTION: Early multimodal treatment of severe sepsis, including the use of drotrecogin alfa (activated) (DrotAA) when indicated, is considered essential for optimum outcome. However, predicting which infected patients will progress to severe sepsis and the need for aggressive intervention continues to be problematic. We therefore wished to explore whether there ...
Wakefield Bonnie J - - 2009
We evaluated the efficacy of two telehealth applications, delivered by telephone and videophone, for improving outcomes of patients following hospital discharge for an acute exacerbation of heart failure. The outcomes measured were patient self-efficacy, satisfaction with care and knowledge of and compliance with prescribed medications. At hospital discharge, patients were ...
Sander Michael - - 2009
INTRODUCTION: During cardiac surgery with cardiopulmonary bypass (CPB) haemodilution occurs. Hepatic dysfunction after CPB is a rare, but serious, complication. Clinical data have validated the plasma-disappearance rate of indocyanine green (PDR ICG) as a marker of hepatic function and perfusion. Primary objective of this analysis was to investigate the impact ...
Morelli Andrea - - 2009
INTRODUCTION: Recent clinical data suggest that early administration of vasopressin analogues may be advantageous compared to a last resort therapy. However, it is still unknown whether vasopressin and terlipressin are equally effective for hemodynamic support in septic shock. The aim of the present prospective, randomized, controlled pilot trial study was, ...
Torgersen Christian - - 2009
INTRODUCTION: Despite the key role of hemodynamic goals, there are few data addressing the question as to which hemodynamic variables are associated with outcome or should be targeted in cardiogenic shock patients. The aim of this study was to investigate the association between hemodynamic variables and cardiogenic shock mortality. METHODS: ...
Christian Michael D - - 2009
The objective of this pilot study was to assess the usability of the draft Ontario triage protocol, to estimate its potential impact on patient outcomes, and ability to increase resource availability based on a retrospective cohort of critically ill patients cared for during a non-pandemic period. Triage officers applied the ...
Reeve Julie C - - 2009
QUESTION: Does the instillation of normal saline before suctioning reduce the incidence of ventilator-associated pneumonia in intubated and ventilated adults? DESIGN: Randomised, controlled trial with blinded outcome assessment. SETTING: The medical/surgical intensive care unit of a tertiary oncology hospital in Brazil. PARTICIPANTS: Adults expected to require at least 72 hours ...
Chung Kevin K - - 2009
INTRODUCTION: Acute kidney injury (AKI) is a common and devastating complication in critically ill burn patients with mortality reported to be between 80 and 100%. We aimed to determine the effect on mortality of early application of continuous venovenous hemofiltration (CVVH) in severely burned patients with AKI admitted to our ...
Valenza Franco - - 2009
INTRODUCTION: The aim of this observational study was to investigate the prevalence of endotoxemia after surgery and its association with ICU length of stay. METHODS: 102 patients admitted to a university ICU after surgery were recruited. Within four hours of admission, functional data were collected and APACHE II severity score ...
Sierros V - - 2009
C-reactive protein (CRP), a biomarker of inflammation, has predicted mortality in end-stage respiratory failure and in the critically ill patients. Our aim was to investigate if CRP can predict morbidity and mortality in patients requiring prolonged mechanical ventilation. A prospective study conducted in a ventilator weaning unit of a skilled ...
Surahio Abdul Rashid - - 2009
Necrotizing Fasciitis is a rare progressive disease which results in significant rate of mortality and morbidity if there is any delay in diagnosis and treatment. Objectives of this Prospective observational study were to share our experience of dealing necrotizing fasciitis in terms of different presentations, diagnosis, treatment and outcome during ...
Michelet P - - 2009
BACKGROUND: The aim of this case-control study was to compare the efficacy of non-invasive positive pressure ventilation (NPPV) with that of conventional treatment in patients who develop postoperative acute respiratory failure (ARF) after oesophagectomy. METHODS: Thirty-six consecutive patients with ARF treated by NPPV were matched for diagnosis, age within 5 ...
Karakurt Zuhal - - 2009
To compare volume- and pressure- controlled ventilation (VCV-PCV) as an initial ventilatory mode in chronic obstructive pulmonary disease (COPD) patients. Case-control study conducted in respiratory intensive care unit (RICU) at a large teaching hospital, between January 2002 and January 2004. PCV was applied in 20 COPD patients with ARF more ...
Chan Raquel Pei Chen - - 2009
The objective of this study was to investigate the relationship between different target levels of glucose and the clinical outcomes of patients undergoing cardiac surgery with cardiopulmonary bypass. We designed a prospective study in a university hospital where 109 consecutive patients were enrolled during a six-month period. All patients were ...
Decruyenaere J J Ghent University Hospital, De Pintelaan 185, Ghent, Belgium. - - 2009
Severe sepsis is the major cause of mortality in intensive care units (ICUs). The BOOST study (= B (Belgian) OO (Open Label) ST (Study)) is a Belgian open-label trial designed to pragmatically assess the safety and efficacy of Drotrecogin Alfa (activated) (DAA), the only registered treatment in this indication with ...
Galzerano Antonio - - 2009
This report is aimed at identifying and suggesting a decision-making approach to handle old patients in ICUs in the light of current epidemiological findings and literature. We reviewed the data provided by the GIVITI network on 107,459 patients admitted to 150 Italian ICUs between 2000 and 2005; patients were divided ...
Lei Qian - - 2009
OBJECTIVE: The predictors of prolonged mechanical ventilation after aortic arch surgery with deep hypothermic circulatory arrest have not been comprehensively evaluated. The present study was designed to identify variables associated with prolonged ventilation in a group of aortic arch surgery patients from a single center. DESIGN: A retrospective study. Prolonged ...
Reismann Marc - - 2009
BACKGROUND AND AIMS: The aim of this study was to investigate fast-track concepts in routine pediatric surgery in a university clinic over 1 year. PATIENTS/METHODS: Fast-track concepts were established for procedures requiring hospital admission in patients up to 15 years of age. Patients were studied prospectively from June 2006 to ...
Zarbock Alexander - - 2009
BACKGROUND: Continuous positive airway pressure is a noninvasive respiratory support technique that may prevent pulmonary complications following cardiac surgery. This study was conducted to determine the efficacy of prophylactic nasal continuous positive airway pressure (nCPAP) compared with standard treatment. The primary end points were pulmonary adverse effects defined as hypoxemia ...
Brandt Christian - - 2008
To evaluate whether operating room (OR) ventilation with (vertical) laminar airflow impacts on surgical site infection (SSI) rates. Retrospective cohort-study based on routine surveillance data. Sixty-three surgical departments participating voluntarily in the German national nosocomial infections surveillance system "KISS" were included (a total of 99,230 operations). Active SSI surveillance was ...
Day Kerry M - - 2008
OBJECTIVE: To determine the association between hyperglycemia and outcome in children ventilated for meningococcal sepsis. DESIGN: Retrospective case notes review. SETTING: Eight bedded pediatric intensive care unit in London. PATIENTS: Consecutive children ventilated for meningococcal sepsis 2001-2004. INTERVENTIONS: None. MEASUREMENTS: Peak glucose for the entire admission was determined and mean ...
Pekdemir Murat - - 2010
BACKGROUND: Dietary and lifestyle changes during Ramadan may affect the appearance rate of emergency health problems or increase emergency department (ED) use. OBJECTIVE: This study's aim was to investigate Ramadan's effects on ED use. METHODS: The study group consisted of patients admitted to the ED during Ramadan, and the control ...
Christaki Eirini - - 2008
PURPOSE OF REVIEW: To critically examine the mortality rates of septic shock over the last 25 years to determine if significant improvements have been accomplished. RECENT FINDINGS: A gradual and progressive improvement in mortality rates associated with septic shock has been realized over the few decades. These improvements in outcome ...
Zenk Johannes - - 2009
Diagnostic and treatment modalities have changed substantially over the past years in the field of pediatrics and neonatal medicine. As a result, the indications and outcome after tracheostomy in young patients have evolved. The aim of this study is to present our experience with pediatric tracheostomies and provide an up-to-date ...
Scales Damon C - - 2008
BACKGROUND: Tracheostomy is common in intensive care unit patients, but the appropriate timing is controversial. OBJECTIVE: To determine whether earlier tracheostomy is associated with greater long-term survival. DESIGN: Retrospective cohort analysis. SETTING: Acute care hospitals in Ontario, Canada (n = 114). PATIENTS: All mechanically ventilated intensive care unit patients who ...
Yañez Leticia J - - 2008
OUTCOMES: To compare the benefits of noninvasive ventilation (NIV) plus standard therapy vs. standard therapy alone in children with acute respiratory failure; assess method effectiveness in improving gas exchange and vital signs; and assess method safety. DESIGN: Prospective, randomized, controlled study. SITE: Two pediatric intensive care units in Santiago, Chile, ...
Sogame Luciana Carrupt Machado - - 2008
OBJECT: It has been shown that craniotomy may lead to a decrease in lung volumes and arterial blood gas tensions as well as a change in the respiratory pattern. The purpose of this study was to determine the incidence of postoperative pulmonary complications (PPCs) and the mortality rate in patients ...
Celebi Serdar - - 2008
BACKGROUND: The aim of our study was to evaluate the pulmonary effects of noninvasive ventilation (NIV) with or without recruitment maneuver (RM) after open heart surgery. METHODS: One-hundred patients undergoing coronary artery bypass surgery were randomized into four groups after the operation: 1) RM with sustained inflation during mechanical ventilation ...
Lin Ming-Shian - - 2008
BACKGROUND: To identify predictors of successful noninvasive ventilation (NIV) treatment for patients with acute respiratory failure. METHODS: This was a prospective intervention study of the intensive care unit of a teaching hospital in Chia-Yi, Taiwan. Patients were enrolled if they had acute respiratory failure and had been admitted to the ...
Iapichino Gaetano - - 2008
We evaluated the relationship between the intestinal microbiota composition and clinical outcome in a group of 15 high-risk patients admitted for acute infection and/or surgical/accidental trauma who were treated with systemic antibiotics according to standard intensive care unit (ICU) protocols. There was a high mortality rate amongst these patients, each ...
Fecho Karamarie - - 2008
This study determined the incidence of and identified risk factors for 48 hour (h) and 30 day (d) postoperative mortality after inpatient operations. A retrospective cohort study was conducted using Anesthesiology's Quality Indicator database as the main data source. The database was queried for data related to the surgical procedure, ...
Bouza Emilio - - 2008
OBJECTIVE: Aspiration of endotracheal secretions is a major step in the prevention of ventilator-associated pneumonia (VAP). We compared conventional and continuous aspiration of subglottic secretions (CASS) procedures in ventilated patients after major heart surgery (MHS). MATERIALS AND METHODS: Randomized comparison during a 2-year period. RESULTS: A total of 714 patients ...
García-Vázquez Elisa - - 2008
BACKGROUND AND OBJECTIVES: The Pneumonia Patient Outcomes Research Team (PORT) developed a prediction rule to identify patients with community-acquired pneumonia (CAP) who are at risk for death and other adverse outcomes. Simpler criteria are needed to evaluate risk of mortality in CAP. PATIENTS AND METHODS: Observational study of patients with ...
Morrison C Anne - - 2009
INTRODUCTION: The implementation of the 80-h work week restrictions implemented by the Accreditation Council for Graduate Medical Education (ACGME) in July 2003 were intended, in part, to improve patient outcomes by reducing fatigue-related resident errors. Although concerns were raised regarding the possibility for increased error due to decreased continuity of ...
Rivers Emanuel P - - 2008
Sepsis is a significant problem, and septicemia is the 10th leading cause of death in the United States. Sepsis incidence is increasing, and the mortality rate is 20% to 50% for patients with severe sepsis. This article identifies methods for improving outcomes of severe sepsis and septic shock. Included are ...
Ender Joerg - - 2008
BACKGROUND: The authors compared the safety and efficacy of a newly developed fast-track concept at their center, including implementation of a direct admission postanesthetic care unit, to standard perioperative management. METHODS: All fast-track patients treated within the first 6 months of implementation of our direct admission postanesthetic care unit were ...
Norris Patrick R - - 2008
Complexity is a measure of variation and randomness potentially indicating improvement or deterioration in critically ill patients. Previously, we have shown integer heart rate (HR) multiscale entropy (MSE), an indicator of complexity, predicts death based on long duration (12 h) and dense (>or=0.4 Hz) windows of HR data. However, such ...
Arslankoylu Ali Ertug - - 2008
OBJECTIVE: The objective of this study was to determine whether there there are any associations between time of admission and mortality rates in the pediatric intensive care unit. METHODS: We analyzed retrospectively 210 consecutive admissions to the PICU from November 2005 to April 2006 for patients aged 1 mth to ...
Müller Mario H - - 2008
Abnormalities in cardiocirculatory, respiratory, or coagulatory parameters are frequent after major surgery, but so far, no study has investigated their predictive value for early intensive care unit (ICU) mortality. We aimed to describe and quantify the relation between these parameters that are routinely determined on ICU admission and early death ...
Collier Bryan R - - 2008
BACKGROUND: The profound oxidative stress that occurs following injury results in significant depletion of many endogenous antioxidants (vitamin C, E, selenium). Increasing evidence suggests antioxidant supplementation reduces infectious complications and organ dysfunction following injury and hemorrhagic shock. The purpose of this study was to evaluate the impact of high-dose antioxidant ...
Mosquera Damien - - 2008
Vascular-Physiological and Operative Severity Score for the enUmeration of Mortality and Morbidity (V-POSSUM) is a risk-adjusted scoring system for predicting 30-day mortality in patients undergoing vascular surgery. It can assess surgical performance by comparing predicted deaths with observed deaths. The aim of this analysis was to assess trends in surgical ...
Killeen, Timothy J; Conservation ...
We documented the history of land-use change and migration in eastern Bolivia in five temporal periods: pre-1976, 1976–1986, 1986–1991, 1991–2001, and 2001–2004. We included all land-cover types located below the natural montane tree line (~3000 m), including forest, savanna, scrubland, seasonal wetland, second-growth forest, pasture, and cropland. The rate of ...
Suberviola Borja - - 2008
BACKGROUND: To evaluate the early complications and effect on neurological outcome of methylprednisolone (MP) treatment in spinal cord injury (SCI) patients during the acute phase. METHODS: We retrospectively reviewed the whole cohort of patients admitted to our ICU between January 1994 and December 2005 due to acute SCI. Patients were ...
Maessen J M C - - 2008
BACKGROUND: Enhanced recovery after surgery (ERAS) programs are designed to reduce hospital length of stay by shortening the postoperative recovery period. The intended effect of an accelerated recovery on the length of stay may be frustrated by a delayed discharge. This study was designed to assess the influence of an ...
Türkmen Aygen - - 2008
RATIONALE: Tracheostomy is done mostly in critically ill patients, many of whom may not survive. We still do not know the long term complications of tracheostomy itself; tracheal and subglottic stenosis, and tracheomalacia. OBJECTIVES: To compare the complications of surgical tracheostomy (ST) versus percutaneous dilatational tracheostomy (PDT) by means of ...
Buettner M - - 2008
BACKGROUND: Dynamic variables, for example, systolic pressure variation (SPV), are superior to filling pressures for assessing fluid responsiveness. We analysed the effects of SPV-guided intraoperative fluid management on organ function and perfusion when compared with routine care. METHODS: Eighty patients (44 female and 36 male) undergoing elective major abdominal surgery ...
Iapichino Gaetano - - 2008
We investigated whether preventing hyperglycemia in septic patients affected the plasma concentration of asymmetric-dimethylarginine and if this was associated with clinical benefit. A prospective, multicenter, randomized, controlled, clinical study. Intensive care units (ICU) in three university hospitals. A total of 72 patients admitted for severe sepsis or septic shock, who ...
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