Search Results
Results 701 - 750 of 1677
< 10 11 12 13 14 15 16 17 18 19 20 >
Kotanidou Anastasia - - 2009
The present study aimed to determine whether amino-terminal pro-brain natriuretic peptide (NT-pro-BNP) predicts intensive care unit (ICU) mortality in a cohort of general, noncardiac, critically ill patients. To this end, a total of 233 consecutive mechanically ventilated patients (109 men) having a median age of 60 years and a wide ...
Focht Anne - - 2009
BACKGROUND: The growing number of patients with severe sepsis or septic shock and the resulting mortality rate (30%) require changes in the current protocols used to treat these conditions. Through adaptation of early goal-directed therapy (EGDT), Carolinas Medical Center developed a process improvement strategy for decreasing mortality associated with severe ...
Lehmann Ryan - - 2009
BACKGROUND: Helicopter transport of injured or ill patients in Operation Iraqi Freedom is a necessary but often high-risk endeavor. Our facility initiated a thorough process improvement and standardization initiative after several adverse outcomes. This report describes the results after this initiative, and evaluates the applicability of a civilian transport risk ...
- - 2009
The optimal target range for blood glucose in critically ill patients remains unclear. Within 24 hours after admission to an intensive care unit (ICU), adults who were expected to require treatment in the ICU on 3 or more consecutive days were randomly assigned to undergo either intensive glucose control, with ...
Bilan N - - 2009
This study aimed at evaluating the mortality rate in a PICU applying PRISM-III. Two hundred and twenty one infants and children consecutively admitted to PICU of Tabriz Children's Hospital were studied during a 13 months period of time. Data required for calculating the PRISM-III score were collected during the first ...
Chen Shiuan-Chih - - 2009
BACKGROUND: The purpose of this study was to explore the relationship between severity of illness at admission and mortality of patients with pyogenic liver abscess (PLA). METHODS: Medical records from 298 PLA patients > or =18 years old were reviewed. Severity of illness at admission was evaluated with the Acute ...
Muehling Bernd - - 2009
BACKGROUND: Fast-track recovery programs have led to reduced patient morbidity and mortality after major surgery. In terms of elective open infrarenal aneurysm repair, no evidence is available about such programs. To address this issue, we have conducted a randomized prospective pilot study. METHODS: The study involved prospective randomization of 101 ...
Buise Marc - - 2009
OBJECTIVE: The aim of this study was to evaluate two-lung high-frequency jet ventilation during esophagectomy and evaluate the influence of high-frequency jet ventilation on pulmonary complications as compared with one-lung ventilation. DESIGN: A retrospective study. SETTINGS: A single-center study in a university hospital. PARTICIPANTS: The authors analyzed the data of ...
de Aguilar-Nascimento José E - - 2009
BACKGROUND: Perioperative fluid replacement is a challenging issue in surgical care. The purpose of the present study was to investigate the effect of two different perioperative hydration protocols on the outcome in patients undergoing major abdominal operations. METHODS: This was a prospective study involving 61 patients (42 men/19 women; mean ...
González-Fajardo J A - - 2009
OBJECTIVE: To compare the outcome of the postoperative administration of a restricted or standard intravenous fluid regimen in patients who underwent elective abdominal vascular surgery. The primary end point was postoperative hospital stay. DESIGN: Prospective observer-blinded, randomised controlled trial. MATERIAL AND METHODS: Patients were considered eligible if they underwent transperitoneal ...
Yang Meng - - 2009
OBJECTIVES: Evaluate the impact of an intensive insulin therapy and conventional glucose control protocol during staying in neurological intensive care unit (NICU) on infection rate, days in NICU, in-hospital mortality and long-term neurological outcome in severe traumatic brain injury (TBI) patients. METHODS: A total of 240 patients with severe TBI ...
Teixeira Cassiano - - 2009
OBJECTIVE: The aim of this study was to evaluate the work of breathing (WOB) behavior during a 120-minute successful spontaneous breathing trial (SBT) with T-tube trial, and its predictive value for extubation outcome. DESIGN: A prospective cohort study. SETTING: 2 medical-surgical intensive care units. PATIENTS: Fifty-one consecutive patients mechanically ventilated ...
Boulain Thierry - - 2009
OBJECTIVE: The aim of this study is to examine the potential impact of dopamine therapy on 28-day mortality in adult septic shock. METHODS: For 66 months, clinical data, medications taken before admission, doses of catecholamines used, and biological parameters were recorded prospectively in all patients admitted for septic shock. This ...
Pietrini Domenico - - 2009
In a selected patient population, we evaluated the glycemic response to different infusional policies in the management of posterior cranial fossa tumor (PFT) removal. We analyzed the perioperative course, prospectically collected, of 137 children undergoing 150 surgical procedures. Patients were divided in two groups according to different intraoperative fluids (group ...
Baldesi Olivier - - 2009
OBJECTIVE: This study was designed to determine if bronchoalveolar lavage (BAL) quantitative culture results can be used confidently for the diagnosis of bacterial ventilator-associated pneumonia (VAP) without taking dilution into account. DESIGN: Prospective observational cohort study. SETTING: A 12-bed medical ICU in a teaching hospital. PATIENTS: A total of 241 ...
Lepelletier Didier - - 2009
Patients with mediastinitis after cardiac surgery have higher morbidity and mortality. Describe the characteristics of patients with mediastinitis, determine the mortality within one month, and assess the risk factors associated with mortality. Retrospective cohort study including all adult patients with mediastinitis during the 2002-2006 period at the Nantes University Hospital. ...
Schneider Glenn Todd - - 2009
OBJECTIVES: To determine if the timing of tracheotomy in elderly patients results in less ventilator associated-pneumonia, mortality, and morbidity. STUDY DESIGN: Historical cohort study. SUBJECTS AND METHODS: This study included 158 ICU patients aged >65 who underwent tracheotomy from March 2003 to June 2007. Patient demographics, outcomes, and ventilation data ...
Kono Keiichi - - 2009
Acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) are characterized by a high mortality rate; therefore, ARDS/ALI in humans is a leading cause of morbidity and mortality in critically ill patients. As previously reported, cytokines play a critical role as signaling molecules that initiate, amplify, and perpetuate inflammatory ...
Savioli Monica - - 2009
OBJECTIVE: To investigate whether tight glycemic control, in patients with sepsis, may restore a normal fibrinolysis by lowering plasminogen activator inhibitor (PAI)-1 levels. DESIGN: Prospective randomized clinical trial. SETTING: Three Italian university hospital intensive care units. PATIENTS: Ninety patients with severe sepsis/septic shock. INTERVENTIONS: Patients were randomized to receive either ...
Krimsky W S WS Critical Care Medicine, Franklin Square Hospital, Baltimore, Maryland 21237, USA. - - 2009
Few published data exist with respect to current implementation of interventions that increase patient safety in intensive care units (ICUs) Furthermore, even less published data exist that address implementation of outcome-related methodologies of patient safety interventions in ICUs. The purpose of this study was threefold: (1) to increase implementation rates ...
Preisman Sergey - - 2009
OBJECTIVES: Intraoperative management directed to early extubation of children undergoing cardiac surgery has been suggested as a viable alternative to prolonged postoperative mechanical ventilation. The authors evaluated the safety and efficacy of this approach in a randomized prospective trial. DESIGN: A prospective randomized observational study. SETTING: A single university-affiliated hospital. ...
Yaroustovsky M - - 2009
AIMS: The purpose of this publication is to evaluate the first experiences with the supplemental use of selective endotoxin adsorption cartridges in the treatment of critically ill patients complicated by severe sepsis after cardiac surgery. METHODS: Thirteen patients with Gram-negative sepsis underwent the procedure of selective lipopolysaccharide (LPS) adsorption using ...
Puskarich Michael A - - 2009
INTRODUCTION: Early structured resuscitation of severe sepsis has been suggested to improve short term mortality; however, no previous study has examined the long-term effect of this therapy. We sought to determine one year outcomes associated with implementation of early goal directed therapy (EGDT) in the emergency department (ED) care of ...
Schneider Christian P - - 2009
BACKGROUND: Acute mortality of unselected critically ill patients has improved during the last 15 years. Whether these benefits also affect survival of critically ill patients with secondary peritonitis is unclear as is the relevance of specific prognostic factors, such as source control. METHODS: We performed a retrospective analysis of data ...
Ramku E M D - - 2009
BACKGROUND: To assess clinical features and treatment of children's tracheotomy seen in ENT/Head and Neck Surgery Clinic and Intensive Care Unit at the University Clinical Centre, Prishtina Kosovo. METHOD: A systematic review of the medical records of all patients admitted to the ENT clinic and intensive care unit having tracheotomy ...
Reade Michael C - - 2009
INTRODUCTION: Agitated delirium is common in patients undergoing mechanical ventilation, and is often treated with haloperidol despite concerns about safety and efficacy. Use of conventional sedatives to control agitation can preclude extubation. Dexmedetomidine, a novel sedative and anxiolytic agent, may have particular utility in these patients. We sought to compare ...
Hodder Richard V - - 2009
INTRODUCTION: Early multimodal treatment of severe sepsis, including the use of drotrecogin alfa (activated) (DrotAA) when indicated, is considered essential for optimum outcome. However, predicting which infected patients will progress to severe sepsis and the need for aggressive intervention continues to be problematic. We therefore wished to explore whether there ...
Wakefield Bonnie J - - 2009
We evaluated the efficacy of two telehealth applications, delivered by telephone and videophone, for improving outcomes of patients following hospital discharge for an acute exacerbation of heart failure. The outcomes measured were patient self-efficacy, satisfaction with care and knowledge of and compliance with prescribed medications. At hospital discharge, patients were ...
Sander Michael - - 2009
INTRODUCTION: During cardiac surgery with cardiopulmonary bypass (CPB) haemodilution occurs. Hepatic dysfunction after CPB is a rare, but serious, complication. Clinical data have validated the plasma-disappearance rate of indocyanine green (PDR ICG) as a marker of hepatic function and perfusion. Primary objective of this analysis was to investigate the impact ...
Morelli Andrea - - 2009
INTRODUCTION: Recent clinical data suggest that early administration of vasopressin analogues may be advantageous compared to a last resort therapy. However, it is still unknown whether vasopressin and terlipressin are equally effective for hemodynamic support in septic shock. The aim of the present prospective, randomized, controlled pilot trial study was, ...
Torgersen Christian - - 2009
INTRODUCTION: Despite the key role of hemodynamic goals, there are few data addressing the question as to which hemodynamic variables are associated with outcome or should be targeted in cardiogenic shock patients. The aim of this study was to investigate the association between hemodynamic variables and cardiogenic shock mortality. METHODS: ...
Christian Michael D - - 2009
The objective of this pilot study was to assess the usability of the draft Ontario triage protocol, to estimate its potential impact on patient outcomes, and ability to increase resource availability based on a retrospective cohort of critically ill patients cared for during a non-pandemic period. Triage officers applied the ...
Reeve Julie C - - 2009
QUESTION: Does the instillation of normal saline before suctioning reduce the incidence of ventilator-associated pneumonia in intubated and ventilated adults? DESIGN: Randomised, controlled trial with blinded outcome assessment. SETTING: The medical/surgical intensive care unit of a tertiary oncology hospital in Brazil. PARTICIPANTS: Adults expected to require at least 72 hours ...
Chung Kevin K - - 2009
INTRODUCTION: Acute kidney injury (AKI) is a common and devastating complication in critically ill burn patients with mortality reported to be between 80 and 100%. We aimed to determine the effect on mortality of early application of continuous venovenous hemofiltration (CVVH) in severely burned patients with AKI admitted to our ...
Valenza Franco - - 2009
INTRODUCTION: The aim of this observational study was to investigate the prevalence of endotoxemia after surgery and its association with ICU length of stay. METHODS: 102 patients admitted to a university ICU after surgery were recruited. Within four hours of admission, functional data were collected and APACHE II severity score ...
Sierros V - - 2009
C-reactive protein (CRP), a biomarker of inflammation, has predicted mortality in end-stage respiratory failure and in the critically ill patients. Our aim was to investigate if CRP can predict morbidity and mortality in patients requiring prolonged mechanical ventilation. A prospective study conducted in a ventilator weaning unit of a skilled ...
Surahio Abdul Rashid - - 2009
Necrotizing Fasciitis is a rare progressive disease which results in significant rate of mortality and morbidity if there is any delay in diagnosis and treatment. Objectives of this Prospective observational study were to share our experience of dealing necrotizing fasciitis in terms of different presentations, diagnosis, treatment and outcome during ...
Michelet P - - 2009
BACKGROUND: The aim of this case-control study was to compare the efficacy of non-invasive positive pressure ventilation (NPPV) with that of conventional treatment in patients who develop postoperative acute respiratory failure (ARF) after oesophagectomy. METHODS: Thirty-six consecutive patients with ARF treated by NPPV were matched for diagnosis, age within 5 ...
Karakurt Zuhal - - 2009
To compare volume- and pressure- controlled ventilation (VCV-PCV) as an initial ventilatory mode in chronic obstructive pulmonary disease (COPD) patients. Case-control study conducted in respiratory intensive care unit (RICU) at a large teaching hospital, between January 2002 and January 2004. PCV was applied in 20 COPD patients with ARF more ...
Chan Raquel Pei Chen - - 2009
The objective of this study was to investigate the relationship between different target levels of glucose and the clinical outcomes of patients undergoing cardiac surgery with cardiopulmonary bypass. We designed a prospective study in a university hospital where 109 consecutive patients were enrolled during a six-month period. All patients were ...
Decruyenaere J J Ghent University Hospital, De Pintelaan 185, Ghent, Belgium. - - 2009
Severe sepsis is the major cause of mortality in intensive care units (ICUs). The BOOST study (= B (Belgian) OO (Open Label) ST (Study)) is a Belgian open-label trial designed to pragmatically assess the safety and efficacy of Drotrecogin Alfa (activated) (DAA), the only registered treatment in this indication with ...
Galzerano Antonio - - 2009
This report is aimed at identifying and suggesting a decision-making approach to handle old patients in ICUs in the light of current epidemiological findings and literature. We reviewed the data provided by the GIVITI network on 107,459 patients admitted to 150 Italian ICUs between 2000 and 2005; patients were divided ...
Lei Qian - - 2009
OBJECTIVE: The predictors of prolonged mechanical ventilation after aortic arch surgery with deep hypothermic circulatory arrest have not been comprehensively evaluated. The present study was designed to identify variables associated with prolonged ventilation in a group of aortic arch surgery patients from a single center. DESIGN: A retrospective study. Prolonged ...
Reismann Marc - - 2009
BACKGROUND AND AIMS: The aim of this study was to investigate fast-track concepts in routine pediatric surgery in a university clinic over 1 year. PATIENTS/METHODS: Fast-track concepts were established for procedures requiring hospital admission in patients up to 15 years of age. Patients were studied prospectively from June 2006 to ...
Zarbock Alexander - - 2009
BACKGROUND: Continuous positive airway pressure is a noninvasive respiratory support technique that may prevent pulmonary complications following cardiac surgery. This study was conducted to determine the efficacy of prophylactic nasal continuous positive airway pressure (nCPAP) compared with standard treatment. The primary end points were pulmonary adverse effects defined as hypoxemia ...
Brandt Christian - - 2008
To evaluate whether operating room (OR) ventilation with (vertical) laminar airflow impacts on surgical site infection (SSI) rates. Retrospective cohort-study based on routine surveillance data. Sixty-three surgical departments participating voluntarily in the German national nosocomial infections surveillance system "KISS" were included (a total of 99,230 operations). Active SSI surveillance was ...
Day Kerry M - - 2008
OBJECTIVE: To determine the association between hyperglycemia and outcome in children ventilated for meningococcal sepsis. DESIGN: Retrospective case notes review. SETTING: Eight bedded pediatric intensive care unit in London. PATIENTS: Consecutive children ventilated for meningococcal sepsis 2001-2004. INTERVENTIONS: None. MEASUREMENTS: Peak glucose for the entire admission was determined and mean ...
Pekdemir Murat - - 2010
BACKGROUND: Dietary and lifestyle changes during Ramadan may affect the appearance rate of emergency health problems or increase emergency department (ED) use. OBJECTIVE: This study's aim was to investigate Ramadan's effects on ED use. METHODS: The study group consisted of patients admitted to the ED during Ramadan, and the control ...
Christaki Eirini - - 2008
PURPOSE OF REVIEW: To critically examine the mortality rates of septic shock over the last 25 years to determine if significant improvements have been accomplished. RECENT FINDINGS: A gradual and progressive improvement in mortality rates associated with septic shock has been realized over the few decades. These improvements in outcome ...
Zenk Johannes - - 2009
Diagnostic and treatment modalities have changed substantially over the past years in the field of pediatrics and neonatal medicine. As a result, the indications and outcome after tracheostomy in young patients have evolved. The aim of this study is to present our experience with pediatric tracheostomies and provide an up-to-date ...
< 10 11 12 13 14 15 16 17 18 19 20 >