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Results 301 - 350 of 4251
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Janík Václav - - 2011
OBJECTIVES: To assess the outcome of self-expandable, biodegradable stent insertion for anastomotic strictures following treatment for rectosigmoid carcinoma. METHODS: Three male patients (median age 66) developed benign strictures after radiotherapy and resection of a recto-sigmoid carcinoma. These were resistant to balloon dilatation and prevented stoma reversal. Biodegradable stent insertion was ...
Thourani Vinod H - - 2011
BACKGROUND: The impact of the degrees of renal dysfunction (RD) after aortic valve replacement (AVR) has not been well described. The purpose of this study was to compare patients undergoing AVR with a range of renal function from normal to dialysis-dependence. METHODS: A retrospective review of 2,408 patients undergoing AVR ...
Kamakura Tatsuro - - 2011
Autologous fat grafting for breast augmentation has faced some historical hurdles. However, in recent years it has been gaining acceptance from the medical community. This prospective, nonrandomized open-label study of 20 Japanese women supports the use of autologous fat grafting in breast augmentation and explores enhancement of fat graft tissue ...
Arendt Elizabeth A - - 2011
PURPOSE: The specific aim of this project was to review a homogenous group of patients who had chosen to undergo medial patellofemoral ligament (MPFL) repair to stabilize their patella after repeat (chronic) patellofemoral dislocations and to record the success of this procedure in stabilizing the patella against further lateral dislocations. ...
Willenberg Torsten - - 2011
Patients with renal insufficiency (RI) are frequently excluded from trials assessing various endovascular revascularization concepts in critical limb ischemia (CLI) although information on clinical outcomes is scarce. Consecutive patients with CLI undergoing endovascular lower limb revascularization during a 4.5-year time interval at a tertiary referral center were prospectively followed over ...
Wang Shijie - - 2011
This study aimed to explore the role of surface electromyography (sEMG) on the changes of myoelectric activities of quadriceps femoris and the assessment of its clinical effect before and after selective femoral neurotomy on spastic cerebral palsy with stiff knee. Selective femoral neurotomy was carried out in 15 patients on ...
Elstein Deborah - - 2011
Since bone pathology is a major concern in type 1 Gaucher disease (GD1), we evaluated bone mineral density (BMD) in adults receiving velaglucerase alfa in the seminal Phase I/II and extension trial. Ten treatment-naïve symptomatic patients with GD1 (four men, six women; median age 35years, range 18-62years) were included; of ...
Piazza Michele - - 2011
To compare outcomes of hybrid repair (HR) combining iliac artery stenting and open common femoral endarterectomy (CFE) with open aortoiliac and femoral reconstruction (OR) in patients with extensive iliac and common femoral occlusive disease (IFOD). Between 1998 and 2008, 92 patients (164 limbs) underwent OR and 70 (84 limbs) underwent ...
Rantanen T K - - 2011
Background: The role of fundoplication in the prevention of esophageal adenocarcinoma is controversial. Development of cancer is associated with proliferation and anti-apoptosis, for which little data exist regarding their response to fundoplication. Methods: Ki-67 and Bcl-2 expression was assessed in the esophagogastric junction (EGJ) and the distal and proximal esophagus ...
Ahmed Sheba - - 2011
Objective:  Amiodarone is frequently associated with thyroid dysfunction. Identifying predictors for amiodarone-associated thyroid dysfunction and assessing treatment outcome may aid clinicians in daily practice. Methods:  We included 303 consecutive patients with amiodarone therapy for cardiac arrhythmias (260 with atrial fibrillation and 43 with ventricular arrhythmias). Thyroid function tests were performed ...
Stephen Linda J - - 2011
INTRODUCTION: Levetiracetam (LEV) is a broad spectrum antiepileptic drug (AED) with a unique mechanism of action. This retrospective audit explores outcomes in patients commenced on LEV monotherapy at the Epilepsy Unit at the Western Infirmary, Glasgow, Scotland from 1st January 2001 until 30th June 2009. METHODS: LEV monotherapy was started ...
Ryer Evan J - - 2011
To compare the clinical characteristics, anatomy, and outcomes of patients treated with open mesenteric revascularization (OR) for chronic mesenteric ischemia (CMI) before and after the preferential use of endovascular revascularization (ER). We reviewed a prospective database of 257 patients treated for CMI with OR or ER from 1998 to 2009. ...
Olsson Nicklas - - 2011
PURPOSE: The purpose of this prospective randomized controlled study was to evaluate the long-term results after an acute Achilles tendon rupture in patients treated surgically or non-surgically. The focus was to evaluate whether any improvements occurred between the one and 2-year evaluation. METHOD: Eighty-one patients (67 men, 14 women) with ...
Huisa Branko N BN Department of Neurology, University of New Mexico, Albuquerque, New Mexico 87131, USA. - - 2012
Patients with minor ischemic stroke (MIS) are frequently excluded from thrombolytic therapy. Denial of therapy to these patients, however, remains controversial. We compared outcomes in patients with MIS who received intravenous (IV) tissue plasminogen activator (t-PA) with those who were not treated. We selected adult patients with stroke onset within ...
Maugin E - - 2011
OBJECTIVES: Various indications for internal iliac artery (IIA) revascularisation have been reported. Revascularisations for gluteal ischaemia and buttock claudication remain controversial and uncommon. The objective of the study was to assess the patency of direct conventional revascularisations (CRs) of the IIA in patients with aortoiliac occlusive disease because few studies ...
Dong Z-L - - 2012
  Clinical investigations into postoperative intravenous patient-controlled analgesia (PCA) have indicated interindividual differences in fentanyl consumption. Cytochrome P450 3A4 (CYP3A4) is the main metabolism enzyme of fentanyl, and single nucleotide polymorphisms within the CYP3A4 gene may contribute to the variability of fentanyl analgesic efficacy. The aim of this study was ...
Lund Amalia M - - 2011
Patients with truncus arteriosus often require pulmonary arterial (PA) and/or right ventricular outflow tract (RVOT) reintervention within the first year of repair. However, little is known about the risk factors for early reintervention on the PAs or RVOT in this population. The objective of the present retrospective cohort study was ...
O'Neill Michael - - 2011
OBJECTIVES: To evaluate patient-reported quality-of-life (QOL) domains in patients with head and neck cancer (HNC) treated with intensity-modulated radiotherapy (IMRT); specifically time-based QOL changes compared with baseline and correlation with independent variables. METHODS: Between January 2002 and August 2006, we prospectively administered the University of Washington Quality of Life-Revised assessment ...
Sposto Richard - - 2011
The recently proposed Rolling 6 Phase I study design is an alternative to the standard 3+3 patient cohort design. It was proposed as a way to reduce the time necessary to complete a trial by reducing the downtime during which Phase I trials are suspended for evaluation of dose-limiting toxicity ...
Macmull Simon - - 2011
BACKGROUND: Autologous chondrocyte implantation (ACI) has been shown to have favorable results in the treatment of symptomatic chondral and osteochondral lesions. However, there are few reports on the outcomes of this technique in adolescents. PURPOSE: The aim of this study was to assess pain relief and functional outcome in adolescents ...
Khandhadia S - - 2011
To correlate the response of topical dorzolamide (Trusopt; Merck) in patients with X-linked retinoschisis (XLRS) with genotype. We carried out a retrospective evaluation of four patients (seven eyes) with XLRS, treated with topical dorzolamide. The change in best-corrected visual acuity (VA) and central macular thickness (CMT; central 1 mm subfield ...
Chen Xu-Lin - - 2011
Despite the fact that early excision and grafting have significantly improved burn outcomes, the management of severely burned patients whose burn size exceeds 70% total body surface area (TBSA) still represents a big challenge for burn surgeons all over the world. During the period of 1997-2010 at our centre, aggressive ...
Viliani T - - 2011
Summary.  Total knee arthroplasty (TKA) is a major orthopaedic surgery intervention, indicated for severe haemophilic arthropathy. The aim of our study was to analyse rehabilitation outcome in haemophilic patients after TKA. A consecutive series of 21 patients (23 knees) was retrospectively evaluated. The mean age was 37 ± 8 years (range 22-55). Physiotherapy ...
Yim Haejun - - 2011
We address the clinical application of the suspension type cultured epithelial autografts (CEAs), Keraheal™ (MCTT, Seoul, Korea), along with the effects, application method, merits and demerits thereof. From February 2007 to June 2010, 29 burn patients with extensive burns, participated in the suspension type of CEA clinical test. A widely ...
Cho Min Chul - - 2011
To investigate the incidence of de novo urinary incontinence (UI) after holmium laser enucleation of the prostate (HoLEP) for benign prostatic hyperplasia and to determine predictors of postoperative de novo UI. A total of 204 men who underwent HoLEP and in whom 12-month follow-up data on UI were available were ...
Ishikawa Hideki - - 2011
Background/Aim: In previous studies, we described the beneficial effects of bifidobacteria-fermented milk in patients with ulcerative colitis (UC). Here, we examined the effects of a live Bifidobacterium breve strain Yakult, a probiotic contained in bifidobacteria-fermented milk, and galacto-oligosaccharide (GOS) as synbiotics in UC patients. Methods: Forty-one patients with mild to ...
Chin Sze-Piaw - - 2011
Abstract Background aims. Mesenchymal stromal cells (MSC) may improve cardiac function following myocardial infarction. MSC can differentiate into cardiomyocytes and endothelial cells while exerting additional paracrine effects. There is limited information regarding the efficacy of route for MSC treatment of severe dilated cardiomyopathy (DCM). The aim of this study was ...
Tamburino Corrado - - 2011
BACKGROUND: Transcatheter Aortic Valve Implantation (TAVI) is an emerging alternative to medical therapy reserved to a limited population with severe aortic stenosis. The European consensus document recommended TAVI for prohibitive-risk patients not eligible for conventional surgery (prohibitive risk defined as expected mortality≥20% calculated with the Logistic EuroScore (LES) in association ...
Baumwol Jay - - 2011
OBJECTIVES: This study determined predictors of early post-operative right heart failure (RHF) and its consequences, as well as predictors of those who clinically thrive longer term after insertion of a continuous-flow left ventricular assist device (LVAD). METHODS: Pre-operative and latest follow-up data were analyzed for 40 consecutive patients who received ...
Lurie Fedor - - 2011
OBJECTIVE:: To analyze patient-reported quality of life (QOL) and symptoms in a prospective cohort of CVD patients who was managed within the framework of existing policies. STUDY DESIGN:: Prospective cohort study of 150 patients with C2-C4 clinical class of primary chronic venous disease (CVD). Management consisted of initial conservative measures, ...
Cockburn James - - 2011
BACKGROUND: Percutaneous aortic valve treatments (balloon aortic valvuloplasty (BAV) and transcatheter valve implantation (TAVI) are effective ways to treat patients with symptomatic aortic stenosis when open surgical repair is not feasible or considered too high risk. Large bore vascular access is required, and successful management of this arterial access is ...
Rivas Alejandro - - 2011
OBJECTIVE:: To identify early predictors of long-term facial nerve function after vestibular schwannoma resection. STUDY DESIGN:: Retrospective chart review. SETTING:: Tertiary referral center. PATIENTS:: Subjects with facial nerve weakness despite anatomic preservation of the nerve after removal of vestibular schwannoma. INTERVENTION:: Surgical resection of vestibular schwannoma. MAIN OUTCOME MEASURE:: Facial ...
Tousek Petr - - 2011
The outcome of acute myocardial infarction (AMI) complicated with cardiogenic shock is poor. The aim of this study was to analyse, whether upfront abciximab administration could improve the outcomes of cardiogenic shock. This multicentre open trial randomized 80 patients with AMI complicated by cardiogenic shock expected to undergo primary PCI ...
Chen Wei-Ting WT Department of Hepato-Gastroenterology, Linkou Medical Center, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan 333, Taipei, Taiwan, - - 2011
To investigate the outcomes, as well as risk factors for 6-wk mortality, in patients with early rebleeding after endoscopic variceal band ligation (EVL) for esophageal variceal hemorrhage (EVH). Among 817 EVL procedures performed for EVH between January 2007 and December 2008, 128 patients with early rebleeding, defined as rebleeding within ...
- - 2011
Clinical trials have established the efficacy of ranibizumab for the treatment of neovascular age-related macular degeneration (AMD). In addition, bevacizumab is used off-label to treat AMD, despite the absence of similar supporting data. In a multicenter, single-blind, noninferiority trial, we randomly assigned 1208 patients with neovascular AMD to receive intravitreal ...
Shaw Colette M - - 2011
PURPOSE: To review utility, safety, and efficacy of optional inferior vena cava (IVC) filters in patients 65 years or older at a single institution over a 6-year period. MATERIALS AND METHODS: Retrospective review of permanent and optional IVC filters placed in elderly patients was performed. Older and younger groups were ...
Aquaro Giovanni Donato - - 2011
Bicuspid aortic valve (BAV) is frequently associated with aortic wall abnormalities, including dilation of the ascending aorta and even dissection. We propose 2 new indexes of aortic wall biophysical properties, the maximum rates of systolic distension and diastolic recoil (MRSD and MRDR, respectively), in patients with BAV and matched control ...
Willis Matthew - - 2011
BACKGROUND: The purpose of this study was to determine the outcomes of patients with proximal humeral malunions treated with reverse shoulder arthroplasty (RSA). MATERIALS AND METHODS: Sixteen patients were treated with RSA for sequelae of a proximal humeral fracture with a malunion. Clinical outcomes (American Shoulder and Elbow Surgeons [ASES] ...
Ciccone Anna Maria - - 2011
Objective: Artificial prosthesis of the superior vena cava (SVC) may occlude with time. For this reason, we proposed in 2003 the use of a biological material (bovine pericardium) and devised an original technique to construct the prosthetic conduit. We hereby report the long-term results in 15 patients. Methods: The SVC ...
Wang Xiao-Dong - - 2011
BACKGROUND: Despite dual antiplatelet therapy, the rate of major adverse cardiovascular events (MACE) after percutaneous coronary intervention (PCI) remains high. Ex vivo tests of clopidogrel resistance can predict MACE after PCI. The purpose of this study is to evaluate the clinical impact of adjusting phosphorylation analysis in patients with clopidogrel ...
Alexopoulos Dimitrios - - 2011
BACKGROUND: Simultaneous drug-eluting stent (DES) and bare-metal stent (BMS) implantation is occasionally employed in clinical practice, but its long-term clinical and angiographic outcome is not clear. HYPOTHESIS: We aimed to describe the long-term clinical outcome and the findings of clinically indicated coronary angiography in patients subjected to simultaneous DES and ...
Barysch Mj - - 2011
Background  Melasma treatment remains challenging despite various laser systems available, because of potential side-effects and high recurrence rates. Objective  Non-ablative fractionated photothermolysis (FP) is a promising therapeutic method, long-time results comparing treated vs. non-treated site are lacking. Methods  A total of 14 patients were treated with FP in a split-face ...
Rodriguez-DE LA Corte H - - 2011
Summary.  The literature describes radiosynovectomy (RS) as a good non-surgical option for reducing synovial membrane size and thus the number of haemarthrosis episodes. However, there are still many aspects concerning the beneficial effects of RS that have not been quantified. A total of 156 radiosynovectomies (RS) were performed in 104 ...
Davies D Mark DM Institute of Medical Genetics, School of Medicine, Cardiff University, Cardiff CF14 4XN, United - - 2011
Renal angiomyolipomas are a frequent manifestation of tuberous sclerosis and sporadic lymphangioleiomyomatosis (LAM). These disorders are associated with mutations of TSC1 or TSC2 that lead to overactivation of mTOR complex 1 (mTORC1), suggesting an opportunity for targeted therapy by using mTORC1 inhibitors. This study investigated the efficacy and safety of ...
Han Yaling - - 2011
BACKGROUNDS: The CREATE is a post-marketing surveillance multicenter registry that demonstrated satisfactory angiographic and clinical (at 18 months) outcomes of a biodegradable polymer based sirolimus-eluting stent (EXCEL, JW Medical System, Weihai, China) for the treatment of patients in routine clinical practice. OBJECTIVES: To evaluate the 3-year clinical safety and efficacy ...
McGillicuddy Daniel C - - 2011
ACADEMIC EMERGENCY MEDICINE 2011; 18:1-5 © 2011 by the Society for Academic Emergency Medicine ABSTRACT: Background:  Implementation of rapid response systems to identify deteriorating patients in the inpatient setting has demonstrated improved patient outcomes. A "trigger" system using vital sign abnormalities to initiate evaluation by physician was recently described as ...
Panarello G - - 2011
This article presents the case of a pregnant woman affected by A/H1N1 flu progressed to ARDS requiring rescue therapy by VV ECMO. Due to the early gestational age, the patient was placed on ECMO before delivery. Four weeks after VV-ECMO placement, a Cesarean section was successfully performed while on ECMO ...
Yang Cheng-Chien - - 2011
Abstract Conclusions: Radial forearm free flap (RFFF)-accompanied phonation tube (PT) for voice and speech restoration after pharyngolaryngectomy is promising, especially in phonation efficacy and intelligibility. It offers not only another safe surgical option but also a satisfactory result for such patients with advanced hypopharyngeal cancer. Objectives: We use RFFF with ...
Kefer Joelle - - 2011
BACKGROUND.: Percutaneous transcatheter closure of patent foramen ovale (PFO) and atrial septal defect (ASD) has been shown to be feasible. AIM.: The aim of the present study was to evaluate the safety and efficacy of transcatheter interatrial septal shunt closure with prosthesis implantation in adults patients during long term follow-up. ...
Bölling Tobias - - 2011
PURPOSE: : Total body irradiation (TBI) is a standard treatment modality within the multidisciplinary approach for allogeneous stem cell or bone marrow transplantation. However, surviving patients are at risk for developing a variety of late sequelae. This analysis aimed to retrospectively characterize late effects after TBI in adults treated in ...
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