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des Champs-Bro B - - 2011
Invasive fungal infections (IFI) are associated with high rates of morbidity and mortality, particularly in onco-haematology patients. We aimed to study the epidemiology of IFI in neutropenic patients and estimate the economic impact of treatment of those infections. All patients hospitalized in onco-haematology, and treated with antifungal agents, in 2005 ...
King Ashley B - - 2011
Botulinum toxin (BTX) has emerged as a treatment of refractory overactive bladder (OAB) and, while well tolerated, there exists concern regarding postoperative urinary retention. A 75-year-old female underwent intravesical BTX-A injection, which was followed by a prolonged episode of urinary retention, highlighting an unusual duration and degree of UR associated ...
Mezoff Ethan E Division of Gastroenterology, Hepatology & Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, - - 2011
Recent changes in the epidemiology of Clostridium difficile infection include an increase in the incidence of C difficile-associated disease (CDAD) and the identification of patients with inflammatory bowel disease (IBD) as a group at risk. In addition, the effectiveness of antimicrobial therapies has been questioned. Our aim was to estimate ...
Arpey Christopher J - - 2011
Christopher Arpey, MD has indicated no significant interest with commercial supporters.
Lamb Jonathan N - - 2011
Spontaneous aneurysmal subarachnoid haemorrhage (SAH) is managed as a neurosurgical priority with guidelines and published literature emphasising the identification and the treatment of the ruptured aneurysm within 48 h of ictus. We audited the timing of management of good grade (WFNS 1 & 2) SAH in a neurosurgical unit in Greater ...
Nilsson Anna Christine - - 2011
Rheumatoid arthritis (RA) is a chronic disease with autoimmune traits of unknown aetiology which primarily affects synovial joints. Glucocorticoids (GCs) are still widely used in RA treatment despite the expanding use of targeted and very efficient agents. The objective of this study was to assess the impact of treatment with ...
Holz Frank G - - 2011
To evaluate the safety and efficacy of individualized ranibizumab treatment in patients with neovascular age-related macular degeneration. Twelve-month, phase III, multicenter, open-label, single-arm study. A total of 513 ranibizumab-naïve SUSTAIN patients. Three initial monthly injections of ranibizumab (0.3 mg) and thereafter pro re nata (PRN) retreatment for 9 months based ...
Ramadan Shahira Abd El-Rahman - - 2011
BACKGROUND Acne scarring is common but surprisingly difficult to treat. Newer techniques and modifications to older ones may make this refractory problem more manageable. The 100% trichloroacetic acid (TCA) chemical reconstruction of skin scars (CROSS) method is a safe and effective single modality for the treatment of atrophic acne scars, ...
Tierney Emily P - - 2011
An increasing array of minimally invasive treatment modalities have evolved for periorbital rhytids. Nonablative fractional photothermolysis has been demonstrated to be effective for periorbital rhytids. We sought to prospectively evaluate eyelid tightening with an ablative fractional photothermolysis laser. We conducted a prospective, single blinded study for lower eyelid laxity in ...
Nielsen Matthew D - - 2011
Nonoperative therapy for adult-acquired flatfoot is a reasonable treatment option that is likely to be beneficial for most patients. In this article, we describe the results of a retrospective cohort study that focused on nonoperative measures, including bracing, physical therapy, and anti-inflammatory medications, used to treat adult-acquired flatfoot in 64 ...
Schneider Philine - - 2011
BACKGROUND:: Hypertension is a major risk factor of Alzheimer's disease (AD); however, controlled studies on the effect of antihypertensive treatment on the risk of dementia are inconclusive. Therefore, a biological marker that predicts individual response to antihypertensive treatment would be of high clinical relevance. Midregional proatrial natriuretic peptide (MR-proANP), an ...
Schumacher Martin - - 2011
PURPOSE: To study the efficacy and safety of a new sclerosing gel of absolute ethanol in the percutaneous treatment of venous malformations (VM). MATERIALS AND METHODS: In this prospective, non-randomized multicenter study patients with clinically and by magnetic resonance imaging diagnosed VM were treated. Efficacy and safety of the gel ...
Kusuhara Hirohisa - - 2011
We undertook a randomized controlled trial of subzone II fingertip amputations, comparing standard treatment with topical application of gelatin microspheres prepared with basic fibroblast growth factor (b-FGF) to provide a slow, sustained release of b-FGF with microsphere degradation. Forty-eight digits from 42 patients were randomized into the two study arms. ...
El-Fateh Tarek - - 2011
Abstract Objective: The objective of this study was to reassess the dento-skeletal treatment effects and the amount of anchorage loss during reduced mandibular splint (RMS) Herbst treatment. Materials and Methods: One hundred consecutive Class II patients treated with a RMS-Herbst appliance were analyzed. The mean pretreatment age of the patients ...
Gao Linggen - - 2011
Aim:  To assess the effect of beta-blockade therapy on progressive aortic dilatation and on clinical outcome in children and adolescents with Marfan's syndrome. Methods:  The meta-analysis was instituted, which included studies identified by a systematic review of MEDLINE of peer-reviewed publications. Echocardiogram measurements of the aortic root dimension and outcome ...
Alessi Sheila M SM University of Connecticut Health Center, Calhoun Cardiology Center - Behavioral Health, 263 Farmington Avenue, Farmington, CT 06030-3944, USA. - - 2011
Marijuana use is common in patients seeking treatment for cocaine use. Nevertheless, few studies have examined effects of marijuana use on treatment outcomes in general, and even fewer with respect to contingency management (CM) treatment, which has been criticized for potentially increasing non-reinforced drug use. Data from three randomized clinical ...
Giovenazzo Pierre - - 2011
The objective of this study was to measure the efficacy of two organic acid treatments, formic acid (FA) and oxalic acid (OA) for the spring control of Varroa destructor (Anderson and Trueman) in honey bee (Apis mellifera L.) colonies. Forty-eight varroa-infested colonies were randomly distributed amongst six experimental groups (n = 8 ...
He L - - 2011
The study evaluated the long-term efficacy and safety profiles of self-intracavernous injection of prostaglandin E1 (PGE1) for erectile dysfunction (ED). Four hundred and sixteen ED patients were treated with self-intracavernous injection of PGE1 from January 1998 to December 2007 in our outpatient service. Follow-up was made to investigate the efficacy ...
London Nicholas J - - 2011
Osteoarthritis affects 27 million American adults of all ages and is a leading cause of disability in middle-aged and older adults. Initial management of knee osteoarthritis symptoms utilizes conservative care although long-term efficacy is poor. Arthroplasty and high tibial osteotomy may be considered for patients with severe pain or disability. ...
Jameson Simon S - - 2011
To the Editor: Lassen and colleagues (Dec. 23 issue)(1) should be congratulated for striving to reduce thromboembolic events after hip replacement, but their choice of primary efficacy outcome, which combines clinically important variables (death and symptomatic venous thromboembolism) with venographically proven deep-vein thrombosis, provokes concern. Neither mortality nor the rate ...
van Rappard D C - - 2011
Background:  Hidradenitis suppurativa (HS) can be associated with several forms of arthritis, usually considered as reactive arthritis. A new observation is that some HS patients develop arthritis after treatment with infliximab (anti-TNF-alpha). Objectives:  A retrospective study was performed to establish the frequency and clinical presentation of new onset arthritis during ...
- - 2011
To the Editor: Lassen and colleagues (Dec. 23 issue)(1) should be congratulated for striving to reduce thromboembolic events after hip replacement, but their choice of primary efficacy outcome, which combines clinically important variables (death and symptomatic venous thromboembolism) with venographically proven deep-vein thrombosis, provokes concern. Neither mortality nor the rate ...
Proebstle Thomas M - - 2011
Radiofrequency segmental thermal ablation (RSTA) has become a commonly used technology for occlusion of incompetent great saphenous veins (GSVs). Midterm results and data on clinical parameters are still lacking. A prospective multicenteral trial monitored 295 RSTA-treated GSVs for 36 months. Clinical control visits included flow and reflux analysis by duplex ...
Kakuda Wataru - - 2011
ABSTRACT The combination treatment of low-frequency repetitive transcranial magnetic stimulation (rTMS) and intensive occupational therapy was applied with concomitant oral administration of levodopa in five post-stroke patients with upper limb hemiparesis (age at treatment: 56-66 years; interval between onset of stroke and treatment: 18-143 months) as a 15-day inpatient protocol. ...
Chen Chih-Hsin - - 2011
The purpose of this study was to evaluate the effects of intravitreal bevacizumab (ivBe) injection in patients with persistent macular edema after macular epiretinal membrane (ERM) removal. This retrospective study included 26 patients (26 eyes) with marked macular edema after complete removal of idiopathic macular ERM who received single ivBe ...
Buster M C A - - 2011
This study aims to asses the influence of inhalable heroin on pulmonary function in chronic heroin-dependent patients treated with inhalable heroin. Among 32 patients (all cigarette smokers), a spirometric test was conducted at baseline and after an average period of 10 months of treatment with medically prescribed heroin. Patients showed ...
Cheatham Joseph G - - 2011
Achalasia is a primary esophageal motility disorder characterized by aperistalsis and incomplete or absent relaxation of the lower esophageal sphincter (LES). The cause of the disease remains elusive and there is no intervention that improves the esophageal body function. Currently, treatment options focus on palliation of symptoms by reducing the ...
Luján S - - 2011
OBJECTIVE: To evaluate the efficacy of a third endoscopic injection to correct vesicoureteral reflux (VUR). PATIENTS AND METHODS: This was a prospective study of 605 patients, of whom 42 (6.4%), involving 44 (4%) ureteral units, received a third injection. The results were analysed regarding VUR grade and aetiology, substance used, ...
Pascual-Salcedo Dora - - 2011
Objective. To analyse the clinical relevance of the production of anti-infliximab antibodies (anti-infliximab Abs) in patients with RA undergoing infliximab treatment over a prolonged period of time. Methods. Clinical characteristics, serum trough infliximab and antibody levels were evaluated in 85 RA patients treated with infliximab for a median of 4.42 ...
Abed Husam - - 2011
INTRODUCTION AND HYPOTHESIS: This study describes the incidence, risk factors, and treatments of graft erosion, wound granulation, and dyspareunia as adverse events following vaginal repair of pelvic organ prolapse with non-absorbable synthetic and biologic graft materials. METHODS: A systematic review in Medline of reports published between 1950 and November 2010 ...
Di Sante Luca - - 2011
Initial treatment of trapeziometacarpal osteoarthritis (TMO) often consists of intra-articular injection of corticosteroids or hyaluronic acid. Several studies have shown that ultrasound (US)-guided injections demonstrate greater precision and effectiveness when compared to blind techniques. The aim of our study was to describe a simple and reliable procedure of US-guided intra-articular ...
Mynderse Lance A - - 2011
We determined the safety, effectiveness and 5-year durability of the new generation, cooled, high energy microwave treatment Cooled ThermoCath® catheter with the Targis® cooled high energy transurethral microwave thermal therapy system by performing a prospective, multicenter trial in men with lower urinary tract symptoms and clinical benign prostatic hyperplasia. At ...
Akarsu S - - 2011
Background.  There is a wide spectrum of treatments available for actinic keratosis (AK). Topical diclofenac sodium and imiquimod are two topical treatments, which are noninvasive, easily applied, well-tolerated and effective. Aim.  To compare the effects of topical 3% diclofenac sodium plus hyaluranon (DFS) gel, 5% imiquimod (IMQ) cream, and base ...
Kobashi Haruhiko H Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama Department of Clinical Research, Center for Liver Disease, Kawasaki Hospital, Kawasaki Medical School, Kawasaki Department of Internal Medicine, Tsuyama Central Hospital, Tsuyama, - - 2011
  We conducted this prospective study to elucidate the long-term outcome and incidence of hepatocellular carcinoma (HCC) development after nucleos(t)ide analog (NA) treatment in patients with chronic hepatitis B (CHB) or cirrhosis.   CHB or cirrhosis patients without past NA treatment or HCC were started on entecavir (ETV) or lamivudine ...
Graf Wilhelm - - 2011
Injection of a bulking agent in the anal canal is an increasingly used treatment for faecal incontinence, but efficacy has not been shown in a controlled trial. We aimed to assess the efficacy of injection of dextranomer in stabilised hyaluronic acid (NASHA Dx) for treatment of faecal incontinence. In this ...
Ng Andrew Tze Ming - - 2011
RATIONALE: Predicting which patients with obstructive sleep apnea (OSA) will be successfully treated with mandibular advancement splints (MAS) remains elusive. Developing simple daytime measurements and tests to predict treatment outcome would enhance MAS treatment. OBJECTIVE: The purpose of this study was to assess the clinical utility of anthropomorphic measurements and ...
Derton Nicola - - 2011
INTRODUCTION: Tooth flaring of the anterior segment is often unesthetic and therefore a primary reason for combined orthodontic and periodontal treatment in adult patients with periodontal disease. Thus, a multidisciplinary approach is frequently chosen for these patients by a qualified dental team. MATERIALS AND METHODS: A clinical case of an ...
Che Yanhua - - 2011
Objective: To describe the patterns of patients' attendance over the first three quarters of a year under methadone maintenance treatment (MMT) clinics in Yunnan Province, China. Methods: Data were obtained from drug abuse treatment databases from five MMT clinics in Yunnan Province. Patients registered between April 2007 and December 2007 ...
Pflugfelder A - - 2011
Background  Actinic keratoses (AK) are carcinomata in situ with the potential to develop into invasive carcinoma. Several studies have demonstrated that 3% diclofenac in 2.5% hyaluronic acid gel (HA) is effective and well tolerated in the treatment of AK. To date there are no large randomized multicentre trials with treatment ...
Cho Sung Bin - - 2011
BACKGROUND Treatment of syringoma aims to destroy the dermal tumor using methods that can include surgical excision, electrodessication, cryosurgery, chemical peeling, and laser ablation, but complete removal of syringomas is often unsuccessful, and recurrence occurs frequently. OBJECTIVE To investigate the therapeutic efficacy of an ablative 10,600-nm carbon dioxide fractional laser ...
Yeung Chi K - - 2011
BACKGROUND Liposome used in spray form to encapsulate and deliver 5-aminolevulinic acid (5-ALA) into the pilosebaceous unit lowers the concentration of 5-ALA to 0.5% in photodynamic therapy (PDT) for acne, with low post-treatment photosensitivity. OBJECTIVE To investigate the clinical outcome and side effects of PDT using intense pulsed light (IPL) ...
Klarenbeek Naomi B - - 2011
OBJECTIVE: /st> To compare clinical and radiological outcomes of four dynamic treatment strategies in recent-onset rheumatoid arthritis (RA) after 5 years follow-up. METHODS: /st> 508 patients with recent-onset RA were randomly assigned into four treatment strategies: sequential monotherapy; step-up combination therapy; initial combination with prednisone; initial combination with infliximab. Treatment ...
Karthikeyan Ganesan - - 2011
Serious bleeding and embolic events are common after fibrinolytic therapy (FT) for left-sided prosthetic valve thrombosis (PVT), and are believed to occur more frequently with prolonged fibrinolytic infusions. But there is no data from prospective studies examining this contention. Our aim was to determine the timing of adverse events after ...
Radvanska E - - 2011
PURPOSE: The alternative treatments for enuresis have been reported with high efficacy but in noncontrolled studies. Therefore, using a prospective, single-blind, randomized, placebo controlled design we evaluated the effect of laser acupuncture on bladder reservoir function and enuresis frequency in cases of monosymptomatic nocturnal enuresis with reduced maximal voided volume. ...
Demir Hac─▒ Ahmet - - 2011
Febrile neutropenia (FEN) is a leading complication of intensive chemotherapy. With this prospective randomized study, the authors aimed to compare the effectiveness of sulbactam-cefoperazone (SC) versus carbapenems, as empirical monotherapy in febrile neutropenic children with lymphoma and solid tumors. Febrile neutropenic children (age ≤16 years) hospitalized at the authors' center ...
Alghamdi Khalid M - - 2011
BACKGROUND The treatment of periungual warts is a therapeutic challenge. Various treatment modalities can be ineffective and may cause scarring and permanent nail changes. OBJECTIVES A prospective pilot study to investigate the efficacy and safety of a low concentration (0.1 U/mL) of bleomycin in the treatment of periungual warts. METHODS Periungual ...
Pérez-Medina Tirso - - 2011
To describe the evolutive endometrial hysteroscopic patterns in patients undergoing long-term tamoxifen treatment. Prospective analysis. Analysis of variance test with post hoc Bonferroni test and homogeneity test of percentages were used for hypothesis contrast between the groups. Canadian task force II-2. Four Spanish tertiary care hospitals. A total of 278 ...
Safer Debra L - - 2011
Extend understanding of a rapid response (RR) to treatment by examining its prognostic significance at end-of-treatment (EOT) and 1 year follow-up within two group treatments for binge eating disorder (BED): Dialectical Behavior Therapy for BED (DBT-BED) and an active comparison group therapy (ACGT). 101 adults with BED randomized to 20-weeks ...
Khedr Eman M - - 2011
BACKGROUND: . Rapid rate magnetic stimulation of human sacral nerve roots can reduce stress incontinence. OBJECTIVE: . To test stimulation for urgency incontinence due to lumbosacral plexopathy. METHODS: . The authors studied patients with intractable neurogenic urinary dysfunction due to lumbosacral nerve injuries. Eligible patients were randomized to receive either ...
Noble Adam J - - 2011
BACKGROUND:: Subarachnoid hemorrhage (SAH) patients illustrate a chronic fear of recurrence. A third of patients develop posttraumatic stress disorder (PTSD) following SAH, and PTSD after other conditions is associated with a more negative outlook on life. OBJECTIVE:: We examined whether recurrence fears are related to PTSD and whether this is ...
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