Search Results
Results 401 - 450 of 1040
< 4 5 6 7 8 9 10 11 12 13 14 >
Penza Paola - - 2008
Buprenorphine is a potent opioid available as a transdermal delivery system (TDS) formulation. This open-label study investigated its safety, tolerability, and efficacy in 30 patients with chronic painful neuropathy. Subjects with visual analogue scale (VAS) score > or = 5 under stable analgesic treatment were entered. The starting dosage of ...
Koseoglu Banu Gurkan - - 2008
PURPOSE: Non-steroidal anti-inflammatory drugs (NSAID) are frequently used in oral surgical procedures in dentistry. The evaluation of the frequency of sister chromatid exchange (SCE) is accepted as a reliable cytogenetic method to assess the genotoxic effects of environmental factors. MATERIALS AND METHODS: In this study, the genotoxic effects of various ...
Jovic R - - 2008
PURPOSE: Recently, nonsteroidal analgoantipyretics are recommended in the management of postoperative pain, with great attention to their safety. We conducted a randomized, single blind study to compare the analgesic efficacy and safety of ketoprofen and dipyrone (metamizole) after major head and neck surgery. PATIENTS AND METHODS: 60 patients received postoperatively ...
Mirshahi Ahmad - - 2008
PURPOSE: A prospective, randomized clinical trial was conducted to assess the usefulness of preoperative diclofenac eye drops in maintaining mydriasis during vitrectomy and in reducing postoperative inflammation. METHODS: Fifty consecutive patients undergoing vitrectomy were randomly assigned to diclofenac (n = 24) or control (n = 26) groups. All patients received ...
Cesarone M R - - 2008
Patients (with venous or arterial disease) are particularly affected by even minor sprains as edema, swelling are more disabling and cause a more severe clinical picture. In such vulnerable population, it is imperative to rehabilitate the patient in shortest possible time to regain the functionality of the injured joint and ...
Pisco João M - - 2008
PURPOSE: To evaluate whether pelvic pain following uterine artery embolization (UAE) can be decreased by using ketoprofen mixed with polyvinyl alcohol (PVA). MATERIALS AND METHODS: A randomized prospective study was performed in 80 patients (age range, 25-52 years; mean age, 41 years) undergoing UAE with PVA between March and August ...
Laine Loren - - 2008
BACKGROUND & AIMS: Nonsteroidal anti-inflammatory drugs (NSAIDs) cause lower gastrointestinal (GI) clinical events such as bleeding. Cyclo-oxygenase (COX)-2 selective inhibitors decrease upper GI events, but no prospective trial has prespecified assessment of lower GI clinical events. METHODS: Patients >or=50 years old with osteoarthritis or rheumatoid arthritis were randomly assigned to ...
McKean Simon A - - 2008
To assess the effect of postoperative diclofenac on the posttonsillectomy hemorrhage rate in adults. Retrospective chart review with Caldicott Guardian approval of patients before and after a change in the postoperative drug regimen. One hundred ninety-three adults between 16 and 56 years, American Society of Anesthesiologists Grade I, listed for ...
Cisár Peter - - 2008
OBJECTIVE: The safe and efficacious use of Pycnogenol (French maritime pine bark extract) in other inflammatory diseases prompted this study of its antiinflammatory effects in patients with osteoarthritis (OA). The aim of the study was to evaluate whether Pycnogenol reduces the symptoms of OA in a double-blind, placebo-controlled, randomly allocated ...
Nadstawek J - - 2008
Opioid-induced constipation can have a major negative impact on patients' quality of life. This randomised clinical trial evaluated patient assessment of the efficacy and tolerability of oral prolonged-release (PR) oxycodone when co-administered with oral naloxone PR. Two hundred and two patients with chronic cancer- or non-cancer-related pain undergoing stable oxycodone ...
Berlin Joshua M - - 2008
BACKGROUND: Actinic keratoses are increasingly common skin lesions that are evaluated and treated by dermatologists on a daily basis. It is estimated that more than 90% of actinic keratoses in the US are treated by destructive therapies, such as cryosurgery. The purpose of this study was to evaluate the efficacy ...
Mastrolonardo M - - 2009
This paper reviews retrospectively the results obtained in a case series of multiple refractory actinic keratoses (AKs), treated sequentially with topical diclofenac 3% gel followed by cryotherapy. In total, 29 patients were reviewed; all had >or= 5 lesions (mean 8.2; range 5-12) and a long-term history of recurrence after repeated ...
Moffet Howard H - - 2008
OBJECTIVE: This study sought a fair sample of published acupuncture clinical trials to assess whether they provided scientific rationales for their interventions, clearly differentiated their exposures or observed differences in outcomes. STUDY DESIGN AND SETTING: A systematic review of all controlled, clinical trials of acupuncture published in English in 2006 ...
Janssens Hein J E M - - 2008
BACKGROUND: Non-steroidal anti-inflammatory drugs and colchicine used to treat gout arthritis have gastrointestinal, renal, and cardiovascular adverse effects. Systemic corticosteroids might be a beneficial alternative. We investigated equivalence of naproxen and prednisolone in primary care. METHODS: We did a randomised clinical trial to test equivalence of prednisolone and naproxen for ...
Snir Nimrod - - 2008
PURPOSE: We assessed the efficacy of papaverine hydrochloride, a commonly used smooth muscle relaxant, for the treatment of renal colic as a single agent and in combination with sodium diclofenac. MATERIALS AND METHODS: A prospective, single-blind clinical study was performed at 2 centers. A total of 86 patients with acute ...
Sun Tiffany - - 2008
BACKGROUND: Controversy continues to surround the use of cyclooxygenase (COX)-2 inhibitors in the perioperative period. We designed this randomized, double-blind, placebo-controlled study to examine the hypothesis that administration of celecoxib preoperatively or postoperatively and for 3 days after major plastic surgery would improve pain control and clinically important patient outcomes. ...
Guo Aisong - - 2008
OBJECTIVE: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. METHODS: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. RESULTS: ...
Zhao Yaping - - 2008
OBJECTIVE: To compare the therapeutic effect of acupuncture for gastrointestinal neurosis with that of oral remedy. METHODS: Eighty cases were randomly divided into the following 2 groups. In the treatment group, acupuncture was given for one month at the main points of Zhongwan (CV 12), Zusanli (ST 36), Taichong (LR ...
Anwari Jamil S - - 2008
OBJECTIVE: To compare the opioid sparing effect of meloxicam, diclofenac, and placebo after abdominal hysterectomy. METHODS: This study was conducted at the Riyadh Military Hospital, Riyadh, Kingdom of Saudi Arabia from February 2004 to November 2006. Women of American Society of Anesthesiologist's classification I or II of ages 25-60 years ...
Starkoff, Brooke
The Swisswing® Biomechanical Stimulation Device has been previously used to treat muscle soreness. It is a form of vibration therapy that is beneficial in increasing circulation to treated muscles. Purpose: To determine the effectiveness of the Swisswing® Biomechanical Stimulation device for decreasing biochemical markers of muscle damage and inflammation and ...
Smirnov Grigori - - 2008
OBJECTIVE: To assess the efficacy of etoricoxib in pain treatment during thyroid surgery. DESIGN: Double-blind, placebo-controlled, randomized trial. SETTING: A secondary-level central hospital in Finland. PATIENTS: Sixty-nine consecutive patients (59 women) aged 18 to 70 years who underwent thyroid surgery. INTERVENTIONS: Patients were randomized to receive etoricoxib 120 mg (n ...
Shemer Avner - - 2008
OBJECTIVE: The purpose of this study was to evaluate the efficacy and tolerability of a mucoadhesive patch compared with a pain-relieving oral solution for the treatment of aphthous stomatitis. METHODS: Patients with active aphthous stomatitis were randomly treated either once a day with a mucoadhesive patch containing citrus oil and ...
Asano Sayaka - - 2008
PURPOSE: To compare the effectiveness of a topical nonsteroidal drug (diclofenac 0.1%) and a topical steroidal drug (betamethasone 0.1%) in preventing cystoid macular edema (CME) and blood-aqueous barrier (BAB) disruption after small-incision cataract surgery and foldable intraocular lens (IOL) implantation. SETTINGS: Shohzankai Medical Foundation Miyake Eye Hospital, Tokyo, Japan. METHODS: ...
Wang Xiao-Yun - - 2008
A randomized single-blind trial was conducted to evaluate the efficacy of short-term abdominal acupuncture as a novel treatment for insomnia in Chinese women. Forty-four patients between the ages of 22 and 56 were randomly assigned to an acupuncture (n = 23) and a medication group (n = 21). The acupuncture ...
Karow Jens-Hagen - - 2008
OBJECTIVE: This study was undertaken to answer the question: "Is Arnica D4 as efficacious as diclofenac in relation to symptoms and wound healing after foot surgery?" METHODS: In this randomized double-blinded, parallel-group study (GCP-standard), the efficacy of Arnica D4 10 pillules (taken orally, 3 times per day) and diclofenac sodium, ...
Weiss Hans-Rudolf - - 2008
Today, acupuncture therapy is commonly used for pain control throughout the world, although the putative mechanisms are still unclear. A Pub Med search for the key words "Acupuncture" and "Scoliosis" reveals 3 papers only, not containing any results of studies designed for the treatment of scoliosis with the help of ...
Kose Osman - - 2008
BACKGROUND: Topical diclofenac and imiquimod have been reported to be effective in the treatment of actinic keratosis, but a study to compare these two drugs has not been reported yet. OBJECTIVE: To compare the efficacy and safety of topical 3% diclofenac gel plus hyaluronic acid and 5% imiquimod cream in ...
Quercia O - - 2008
Adverse reactions to nonsteroidal anti-inflammatory drugs (NSAIDs) are a frequently reported problem due to the fact that these molecules are often used for control of pain and inflammation. Although the use of selective inhibitors of cyclooxygenase (COX) 2 helps to prevent some of these adverse reactions, they can have cardiac ...
Nishiike Suetaka - - 2007
STUDY OBJECTIVE: To investigate the analgesic efficacy of preoperative flurbiprofen on postoperative pain after tonsillectomy. DESIGN: Prospective, randomized, nonblinded, non-placebo-controlled study. SETTING: Municipal hospital. PATIENTS: Twenty-five ASA physical status I patients older than 20 years of age, who were scheduled for tonsillectomy. INTERVENTIONS: Patients were randomly allocated to two groups ...
Karabuda Zihni Cuneyt - - 2007
BACKGROUND: The analgesic and anti-inflammatory efficacy of tenoxicam and meloxicam were evaluated in this double-masked, randomized, prospective study by analyzing pain scores and the need for rescue-analgesic agents following dental implant surgery. METHODS: One hundred patients, in whom 241 dental implants were placed, were divided into two groups. For 4 ...
Kayali Cemil - - 2007
OBJECTIVE: To assess the efficacy of paracetamol in comparison with diclofenac sodium. METHODS: Between February - November 2006, a prospective, double blinded, parallel group study of 100 patients suffering from first or second degree lateral ankle sprain within 48-hours of admission in Tepecik Education and Research Hospital, Izmir, Turkey. Patients ...
Nimmaanrat S - - 2007
BACKGROUND: To evaluate the postoperative analgesic efficacy of intravenous tramadol 50 mg administered before anesthetic induction in patients undergoing ambulatory gynecological laparoscopic procedures. METHODS: This was a double-blind randomized, controlled trial conducted in 150 patients. Pain intensity was measured using a verbal numerical rating score at 1, 2, 6, 12, ...
Tuzuner Aysegul Mine - - 2007
PURPOSE: The aim of this study was to compare the postoperative analgesic affects of preoperative use of a synthetic opioid tramadol and a nonsteroidal anti-inflammatory drug diclofenac sodium for postoperative pain, with placebo, in patients undergoing bimaxillary osteotomy. PATIENTS AND METHODS: Thirty-six orthognathic surgery patients who underwent both Le Fort ...
Munishankar B - - 2008
BACKGROUND: Few studies have investigated efficacy and side effects of the combination of diclofenac and paracetamol used for pain relief after major surgery. METHODS: After ethical approval, 78 patients, presenting for elective caesarean section, were recruited to this double-blind trial and randomised to receive one of three analgesic modalities: paracetamol, ...
Heaney Mairead - - 2007
BACKGROUND: Tonsillectomy is a common pediatric surgical procedure resulting in significant postoperative pain. There is ongoing controversy as to the most satisfactory analgesic regimen. Nonsteroidal antiinflammatory drugs (NSAIDs) are an alternative to opioids in this setting. NSAID use in tonsillectomy has been shown to be opioid sparing in the recovery ...
Djaladat Hooman - - 2007
OBJECTIVE: To evaluate the efficacy of aminophylline infusion as a painkiller compared with placebo in patients with acute renal colic. PATIENTS AND METHODS: From March to August 2005, 141 patients with clinical renal colic, who were under 60 years of age, had no history of heart or hepatic failure, asthma, ...
Krueger K - - 2008
OBJECTIVE: A randomised, double-blind study to compare the gastrointestinal (GI) tolerability, safety and efficacy of etoricoxib and diclofenac in patients with rheumatoid arthritis (RA). PATIENTS AND METHODS: A total of 4086 patients (mean age 60.8 years) diagnosed with RA were enrolled and received etoricoxib 90 mg daily (n = 2032) ...
Endres Heinz G - - 2007
Acupuncture treatment is frequently sought for tension-type headache (TTH), but there is conflicting evidence as to its effectiveness. This randomised, controlled, multicentre, patient-and observer-blinded trial was carried out in 122 outpatient practices in Germany on 409 patients with TTH, defined as > or =10 headache days per month of which ...
Haake Michael - - 2007
BACKGROUND: To our knowledge, verum acupuncture has never been directly compared with sham acupuncture and guideline-based conventional therapy in patients with chronic low back pain. METHODS: A patient- and observer-blinded randomized controlled trial conducted in Germany involving 340 outpatient practices, including 1162 patients aged 18 to 86 years (mean +/- ...
Shi Hong-fei - - 2007
OBJECTIVE: To evaluate the clinical effect of Chinese herbs combined with acupuncture (CH-A) in treating chloasma. METHODS: Sixty-one patients with chloasma were randomly assigned to two groups: 30 in the control group and 31 in the treated group. Both groups received conventional treatment with oral intake of vitamin C and ...
Zhang Wenli - - 2007
OBJECTIVE: To observe the therapeutic effects of different acupuncture methods for spastic hemiparalysis due to cerebrovascular disorders. METHODS: 90 cases of spastic hemiparalysis after wind-stroke were randomly divided into a control group of 30 cases, a body acupuncture group of 30 cases and a point-penetrating acupuncture group of 30 cases. ...
Snabes Michael C - - 2007
STUDY OBJECTIVE: To assess the analgesic efficacy of a multidose, multiday regimen of intravenous (IV) parecoxib sodium (parecoxib). DESIGN: Multicenter, randomized, double-blind, placebo-controlled, parallel-group trial. SETTING: Postoperative recovery area and inpatient care facility. PATIENTS: 422 patients who had undergone gynecologic surgery via laparotomy participated (day 1), and 414 patients were ...
Likar Rudolf - - 2007
BACKGROUND: In 2001, a transdermal matrix patch formulation of buprenorphine was approved for the treatment of moderate to severe cancer pain and severe pain that is unresponsive to nonopioid analgesics. The primary recommendation contained in the prescribing information was that transdermal patches be worn for a 3-day period before application ...
Benetello V - - 2007
We compared the clinical efficacy of orally administered valdecoxib and piroxicam for the prevention of pain, trismus and swelling after removal of horizontally and totally intrabony impacted lower third molars. Twenty-five patients were scheduled to undergo removal of symmetrically positioned lower third molars in two separate appointments. Valdecoxib (40 mg) ...
Ghiculescu R A - - 2007
BACKGROUND: I.v. paracetamol has recently become available in Australia for the treatment of pain when the oral or rectal administration route is not accessible. Our primary aim was to assess compliance with prescribing guidelines and our secondary aim to evaluate the safety of i.v. paracetamol use (4 g/day) and the ...
Akyol-Salman Ilknur - - 2007
To compare the anti-inflammatory and analgesic effects of topical pranoprofen 0.1% with diclofenac sodium 0.1% after strabismus surgery, 40 patients were prospectively randomized and assigned into 2 groups. Signs and symptoms of inflammation, as well as intraocular pressure (IOP) of patients, were evaluated at 1 day and 1 and 3 ...
Wang Ruihui - - 2007
OBJECTIVE: To observe the effect of acupuncture therapeutic courses on rheumatoid arthritis. METHOD: Forty-seven patients were treated with acupuncture for 6 courses and at the end of the third and sixth course of treatment, the therapeutic effects of acupuncture on morning rigidity, swelling and pain of joints as well as ...
Wulkow R - - 2007
There are few studies supporting the effective and safe use of laxatives for constipation. This study examined the short-term efficacy and safety of sodium picosulphate in patients with chronic constipation. Patients with a history of chronic constipation for at least 3 months were randomised to receive 7 mg sodium picosulphate ...
Bostanci Seher - - 2007
OBJECTIVE: Chemical matricectomy is performed mainly by two agents: phenol and sodium hydroxide. Both agents have excellent cure rates, but there are no data about the comparison of postoperative healing periods. This study was designed to compare the postoperative morbidity rates of sodium hydroxide and phenol matricectomies. MATERIALS AND METHODS: ...
Hassantash Seyed A - - 2007
Indomethacin is a known immune modulator that inhibits cyclooxygenase. Studies indicate that ketoconazole, a selective lipoxygenase and thromboxane A(2) synthetase inhibitor, can prevent activation of the inflammatory cascade by inhibition of proinflammatory mediators. This study was designed to determine if ketoconazole or indomethacin could reduce the adverse effects of extracorporeal ...
< 4 5 6 7 8 9 10 11 12 13 14 >