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Frederiksen Henrik H Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark; Department of Haematology, Odense University Hospital, Odense, - - 2014
Studies have reported a 1·3- to 2·2-fold higher mortality rate among patients with primary immune thrombocytopenia (ITP) compared to the general population. However, long-term mortality estimates as well as cause-specific mortality data are sparse. In our population-based cohort of adult patients with newly diagnosed ITP and up to 37 years of ...
Kim Young Dae YD Department of Neurology, Yonsei University College of Medicine, Seoul, - - 2014
Although early neurological deterioration (END) during the acute stroke period is known to be associated with poor functional outcomes, there is little data regarding the impact of END on long-term outcomes according to the characteristics of END. The aim of this study was to investigate whether there are differences in ...
Linke Axel A Department of Internal Medicine and Cardiology, University of Leipzig Heart Center, Struempellstrasse 39, 04289 Leipzig, - - 2014
Transcatheter aortic valve implantation has become an alternative to surgery in higher risk patients with symptomatic aortic stenosis. The aim of the ADVANCE study was to evaluate outcomes following implantation of a self-expanding transcatheter aortic valve system in a fully monitored, multi-centre 'real-world' patient population in highly experienced centres. Patients ...
Erturk Mehmet M Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Department of Cardiology, Istanbul, - - 2014
Peripheral arterial occlusive disease (PAOD), which is common in male gender and elderly population, is related with increased cardiovascular mortality and morbidity. Neutrophil to lymphocyte ratio (NLR) has been found to be an independent predictor of cardiovascular mortality in atherosclerosis. The aim of the present study was to investigate the ...
Alvin Matthew D MD *Cleveland Clinic Center for Spine Health, Cleveland Clinic, Cleveland, Ohio, USA †Case Western Reserve University School of Medicine, Cleveland, Ohio ‡Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio, USA §Department of Neurosurgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA ∥Department of Neurological Surgery, Cleveland Clinic, Cleveland, Ohio, - - 2014
Retrospective 1-year cost-utility analysis. To determine the cost effectiveness of anterior cervical discectomy and fusion with plating (ACDFP) in comparison to posterior cervical foraminotomy (PCF) for patients with single-level cervical radiculopathy. Cervical radiculopathy due to cervical spondylosis is commonly treated by either PCF or ACDFP for patients who are refractory ...
Darmon Michael M 1 Medical ICU, Saint-Etienne University Hospital, Avenue Albert Raymond, Saint-Priest en Jarez, 42270, France; Jacques Lisfranc Medical School, Saint-Etienne University, Saint-Etienne, France 2 University of Grenoble 1 (Joseph Fourier) Integrated Research Center U 823 - Albert Bonniot Institute, Grenoble University Hospital, Grenoble, France 3 Polyvalent ICU, Grenoble University Hospital, BP217, 38043 Grenoble Cedex 9, France 4 Department of Physiology, Cochin University Hospital, APHP, 75005, Paris, France 5 Surgical ICU, Mondor University Hospital, APHP, 94000, Créteil, France 6 Medical ICU, University Hospital St Louis, 1 Avenue Claude Vellefaux, 75010, Paris, France 7 Medical ICU, Bichat University Hospital, Paris, France; Paris-7 University, Paris, France 8 Medical-Surgical ICU, Avicenne University Hospital, Bobigny, France; Paris-13 University, Bobigny, France 9 Polyvalent ICU, Groupe Hospitalier St Joseph, 145 Rue Raymond Losserand 75014, Paris, France 10 Medical ICU, Gabriel Montpied University Hospital, 58 Rue Montalembert, 63003 Clermont Ferrand Cedex 1, France 11 Polyvalent ICU, Gonesse General Hospital, 25 Rue Bernard Fevrier, 95500, Gonesse, France 12 Intensive care unit, Centre Hospitalier Andrée Rosemon, Av des Flamboyants, BP 6006 97306, Cayenne, France 13 Medical ICU, Hospices Civils de Lyon, Edouard Herriot University Hospital, F-69003 Lyon, France; Lyon University, Lyon-Est Medical School, F-69008, Lyon, France 14 Surgical ICU, Antoine Béclère University Hospital 157 Rue de la Porte de Trivaux, 92141, Clamart Cedex, France 15 Polyvalent ICU, Centre Hospitalier Sud Essonne Dourdan-Etampes - Siège, 26 Avenue Charles de Gaulle, 91150, Etampes, France 16 Medical-Surgical ICU, Hyeres hospital, Hyeres, Frances 17 Surgical ICU, Edouard Herriot University Hospital, Hospices Civiles de Lyon, Lyon, - - 2014
Increasing evidence suggests that dysnatraemia at ICU admission may predict mortality. Little information is available, however, on the potential effect of dysnatraemia correction.Patients and MethodsObservational multicentre cohort study in patients admitted between 2005 and 2012 to 18 French ICUs. Hyponatraemia and hypernatraemia were defined as serum sodium concentration < 135 ...
Caceres Manuel M Division of Cardiothoracic Surgery, Cedars Sinai Medical Center, Los Angeles, CA, - - 2014
Aortic root surgery is transitioning to aortic valve sparing (AVS), but little is known about the relative early outcomes of AVS versus composite graft-valve replacement (CVR). This study assessed mortality differences for AVS versus CVR to guide future practice decisions. From January 2000 to June 2011, 31 747 patients had ...
Ahmadi Zainab - - 2014
The prognostic role of the arterial blood gas tension of carbon dioxide (PaCO2) in severe Chronic Obstructive Pulmonary Disease (COPD) remains unknown. The aim of this study was to estimate the association between PaCO2 and mortality in oxygen-dependent COPD. National prospective study of patients starting long-term oxygen therapy (LTOT) for ...
Firempong Alexander O - - 2014
Objectives: Septic shock (SS) and respiratory failure (RF) are serious complications after neurosurgical procedures. Research is limited in studying racial/ethnic disparities in incidence and mortality of SS and RF. The study aimed to determine the racial variation in incidence and mortality from SS and RF among elective neurosurgical patients in ...
Thorsen Kenneth K Department of Gastrointestinal Surgery, Stavanger University Hospital, PO Box 8100, 4068, Stavanger, Norway, - - 2014
Mortality rates in perforated peptic ulcer (PPU) have remained unchanged. The aim of this study was to compare known clinical factors and three scoring systems (American Society of Anesthesiologists (ASA), Boey and peptic ulcer perforation (PULP)) in the ability to predict mortality in PPU. This is a consecutive, observational cohort ...
Ashebo Gedeon Yohannes - - 2014
Information is needed on the expected durability of insecticidal nets under operational conditions. The persistence of insecticidal efficacy is important to estimate the median serviceable life of nets under field conditions and to plan for net replacement. Deltamethrin residue levels were evaluated by the proxy method of x-ray fluorescence spectrometry ...
Unbehaun Axel A Deutsches Herzzentrum Berlin, Berlin, - - 2014
A major limitation of transcatheter aortic valve implantation (TAVI) is that its long-term outcomes are still unknown. The purpose of this study was to evaluate survival up to 5 years after implantation and to identify predictors of follow-up mortality in a large cohort of patients who underwent exclusively a transapical ...
O'Byrne Michael - - 2014
Nonvariceal upper gastrointestinal bleeding (NVUGIB) is associated with significant mortality. To examine several factors that may impact the mortality and 30-day rebleed rates of patients presenting with NVUGIB. A retrospective study of the charts of patients admitted to hospital in either the Saskatoon Health Region (SHR) or Regina Qu'Appelle Health ...
Tadros Rami O RO Division of Vascular Surgery, Department of Surgery, The Ichan School of Medicine at Mount Sinai, New York, NY. Electronic address: - - 2014
There have been four eras in the development of endovascular aneurysm repair (EVAR): physician-made grafts, early industry devices, intermediary commercial endografts, and modern stent grafts. This study analyzes differences in outcomes between these four groups and the impact of device evolution and increased physician experience. From 1992 to 2012, 1380 ...
Hennig A A Sagarmatha Choudhary Eye Hospital, Lahan, - - 2014
PurposeTo compare the outcomes of phacoemulsification with either a 2.5-mm clear corneal incision and a foldable intraocular lens (IOL) or a 5-mm sclerocorneal tunnel incision and a rigid polymethyl methacrylate (PMMA) IOL.MethodsIn a prospective, randomised clinical trial of phacoemulsification cataract surgery, 1200 patients received either a foldable hydrophilic acrylic IOL ...
Sebag Frédéric A FA Department of Cardiology, Henri Mondor Hospital (Assistance Publique-Hôpitaux de Paris), Creteil, - - 2014
To evaluate the prognostic impact of QRS width in patients with low-flow/low-gradient aortic stenosis (LF/LGAS). Among 88 consecutive patients referred to our institution for LF/LGAS from September 1994 to March 2007, baseline demographic, clinical, echocardiographic, and electrocardiographic data were collected. This population was divided into two groups according to baseline ...
Tuttle John R JR Department of Orthopaedics, Brown University Alpert School of Medicine, Providence, Rhode - - 2014
The purpose of this study was to provide a cost-benefit analysis of topical tranexamic acid (TXA) in primary total hip and knee arthroplasty patients. A retrospective cohort of 591 consecutive patients, 311 experimental and 280 control, revealed a transfusion rate reduction from 17.5% to 5.5%, increased postoperative hemoglobin, and decreased ...
Rollins K E KE Cambridge Vascular Unit, Box 201, Level 6, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, CB2 0QQ, - - 2014
Emergency endovascular repair (EVAR) for ruptured abdominal aortic aneurysm (rAAA) may have lower operative mortality rates than open surgical repair. Concerns remain that the early survival benefit after EVAR for rAAA may be offset by late reinterventions. The aim of this study was to compare reintervention rates and cost-effectiveness of ...
Lalmohamed Arief A Utrecht University and University Medical Center Utrecht, Utrecht, The - - 2014
Total hip arthroplasty (THA) and total knee arthroplasty (TKA) are effective procedures for patients with moderate-to-severe osteoarthritis. Mortality rates after THA and TKA may have changed because of new surgical techniques, improvement of peri- and postoperative care, and performance of surgery in older patients having multiple comorbidities. However, data on ...
Johnson Matthew S MS Department of Otolaryngology, University of Nebraska Medical Center, Omaha, Nebraska, - - 2014
To evaluate the utility of a modified frailty index as an indicator of postoperative mortality in patients undergoing tracheostomy. Case series with chart review. Tertiary care veterans hospital. A chart review was conducted of consecutive tracheostomies performed between April 2007 and September 2012. A modified frailty index consisting of 11 ...
Carrasco-Chinchilla Fernando F Unidad del Corazón, Hospital Clínico Universitario Virgen de la Victoria, Málaga, España. Electronic address: - - 2014
Mortality from left-sided infective endocarditis remains very high. The aim of this study was to assess the impact of a multidisciplinary alert strategy (AMULTEI), based on clinical, echocardiographic and microbiological findings, implemented in 2008 in a tertiary hospital. Cohort study comparing our historical data series (1996-2007) with the number of ...
Blanchette Lisa M LM Lisa M. Blanchette, Pharm.D., is Infectious Diseases Clinical Pharmacy Specialist, Novant Health Presbyterian Medical Center, Charlotte, NC. Paul Huiras, Pharm.D., BCPS, is Surgical Intensive Care Unit Clinical Pharmacy Specialist; and Stella Papadopoulos, Pharm.D., BCPS, is Administrative Director, Clinical and Academic Affairs, Boston Medical Center, Boston, - - 2014
Results of a study comparing clinical and cost outcomes with the use of standardized versus custom-prepared parenteral nutrition (PN) in an acute care setting are reported. In a retrospective pre-post analysis, nutritional target attainment, electrolyte abnormalities, and other outcomes were compared in patients 15 years of age or older who ...
Satrom Katie K Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA and Department of Energy Management, University of Minnesota, Minneapolis, MN, - - 2014
Neonatal hyperbilirubinemia continues to be a leading cause of morbidity and mortality in resource-limited countries. The aim of this study was to measure the effectiveness of existing phototherapy units at a local hospital in Cameroon using an irradiance meter. Phototherapy units (n = 4) in one newborn nursery in Cameroon ...
Kissin Dmitry M DM Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia; and the Center for Human Reproduction, New York, New - - 2014
To assess the association between number of embryos transferred and a measure of assisted reproductive technology success that emphasizes good perinatal outcome. We analyzed assisted reproductive technology cycles initiated in 2011 that progressed to fresh embryo transfer among women using autologous oocytes and reported to the U.S. National Assisted Reproductive ...
Liu Yi Y 1] CAS Key Laboratory of Crust-Mantle Materials and Environments, School of Earth and Space Sciences, University of Science and Technology of China, Hefei 230026, China - - 2014
A large and sudden increase in radiocarbon ((14)C) around AD 773 are documented in coral skeletons from the South China Sea. The (14)C increased by ~ 15‰ during winter, and remain elevated for more than 4 months, then increased and dropped down within two months, forming a spike of 45‰ ...
Leboeuf-Yde Charlotte C Research Department, The Spine Center of Southern Denmark, Hospital Lillebælt and Institute of Regional Health Research, University of Southern Denmark, Østre Hougvej 55, DK5500 Middelfart, Denmark. - - 2014
Over one year, the majority of patients with low back pain (LBP) from the secondary care sector could not report a single week without LBP and few could report a non-episode, defined as at least one month without LBP. Presumably, non-episodes would be more common in the general population. The ...
Pozzi M M Division of Cardiac Surgery, Pitié-Salpêtrière Hospital, University "Pierre et Marie Curie", Paris, France; Ph.D. School in Cardiovascular Science, Cardiovascular Surgery Unit, University of Verona Medical School, Verona, Italy. Electronic address: - - 2014
Heart retransplantation (HRT) accounts for 2.6% of heart transplantation (HT) indications. We performed a retrospective analysis of our recent HRT experience. From January 2000 to June 2012, 820 HTs were performed; 798 (97.3%) were primary HTs and 21 (2.5%) 2nd HTs. Indications for HRT included: 57% cardiac allograft vasculopathy, 33% ...
Aleme Adisu A Amhara Regional state Health Bureau, - - 2014
Understanding the feasibility of achieving widespread coverage with Insecticide-Treated Nets has to be preceded by learning how people value the Insecticide-Treated Nets and estimating the potential demand and willingness to pay so that sustainability of the intervention can be assured. The objective of this study was to determine willingness to ...
Blackman Daniel J DJ Department of Cardiology, Leeds Teaching Hospitals, Leeds, - - 2013
To determine whether outcomes from transcatheter aortic valve implantation (TAVI) vary according to access route and valve type in a real-world population. Registry and uncontrolled trial data have found that patients undergoing nonfemoral TAVI have higher early and late mortality. It is not clear whether worse outcomes relate directly to ...
Turney Eric J EJ Department of Vascular Surgery, Cleveland Clinic Lerner College of Medicine at Case Western Reserve University, Cleveland, - - 2013
With more than a decade of use of endovascular aneurysm repair (EVAR), we expect to see a rise in the number of failing endografts. We review a single-center experience with EVAR explants to identify patterns of presentation and understand operative outcomes that may alter clinical management. A retrospective analysis of ...
Nishida Takahiro T Department of Cardiovascular Surgery, Kyushu University Graduate School of Medical Sciences, Fukuoka, - - 2013
The European System for Cardiac Operative Risk Evaluation (EuroSCORE) II was developed to improve the overestimation of surgical risk associated with the original (additive and logistic) EuroSCOREs. The purpose of this study was to evaluate the significance of the EuroSCORE II by comparing its performance with that of the original ...
Ambler Graeme K GK Department of Vascular Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom. Electronic address: - - 2013
Critical limb ischemia (CLI) is a common condition associated with high levels of morbidity and mortality. Most work to date has focused on surgeon-oriented outcomes such as patency, but there is increasing interest in patient-oriented outcomes such as mobility and independence. This study was conducted to determine the effect of ...
Banerjee Amitava - - 2013
ABSTRACT BACKGROUND Patients with chronic kidney disease (CKD) are more likely to develop atrial fibrillation(AF) than individuals with normal renal function, and are more likely to suffer ischaemic stroke(IS)/thromboembolism(TE). No prior study has considered the impact of eGFR on bleeding. We investigated the relationship of eGFR to IS/TE, mortality and ...
Chandrasegaram Manju D MD HPB Department, Flinders Medical Centre, Adelaide, SA, Australia; Department of Surgery, The University of Sydney, Sydney Medical School, Nepean, Penrith, NSW, - - 2013
Portal vein (PV) resection is used increasingly in pancreatic resections. There is no agreed policy regarding anticoagulation. A systematic review was performed to compare studies with an anticoagulation policy (AC+) to no anticoagulation policy (AC-) after venous resection. There were eight AC+ studies (n = 266) and five AC- studies ...
Lalmohamed Arief A Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute of Pharmaceutical Sciences, Utrecht, Netherlands; Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht, - - 2013
Introduction: THR / TKR surgery are effective procedures for patients with moderate-to-severe osteoarthritis. Mortality rates after THR and TKR may have changed because of new surgical techniques, improvement of peri- and postoperative care, and patients having more comorbidity. Data on secular mortality trends are however scarce. The objective was to ...
Zhao Yang Y Eli Lilly and Company, 893S. Delaware St., Indianapolis, IN, 46285, USA. Electronic address: - - 2013
This study examined the association between teriparatide (TPTD) adherence, and healthcare utilization and costs among hip fracture (HFx) patients. Individuals aged 50years and older with an HFx between 1/1/2002-12/31/2010 were identified from a large US administrative claims database. The first HFx date during this period was designated as the index. ...
Cohen S - - 2013
Background/Objective:To assess the conclusiveness of the Cochrane Reviews (CRs) in the field of Nutrition, we tested the hypotheses that: (1) the majority of CRs is inconclusive; (2) the majority of CRs recognizes the need for further and better studies and (3) the ability to reach a conclusion is dependent on ...
Lane Jordan D - - 2013
Object Antibiotic-impregnated shunts have yet to find widespread use in the developing world, largely due to cost. Given potential differences in the microbial spectrum, their effectiveness in preventing shunt infection for populations in low-income countries may differ and has not been demonstrated. This study is the first to compare the ...
Riera M - - 2013
A study was made to explore the possible association between the perioperative transfusion of 1 - 2 red blood cell units and in-hospital morbidity, 30-day mortality, and long-term survival in patients undergoing heart surgery. A prospective observational study was carried out. The ICU of a university hospital. All patients over ...
Wang Hong-Ling HL Department of Gastroenterology, the Research Center for Clinical Study of Intestinal & Colorectal Diseases of Hubei Province, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China, - - 2013
National data show that in China mainland unsedated gastrointestinal (GI) endoscopy has been applied in most hospitals for clinical examination, while sedated GI endoscopy is only performed in some hospitals. The purpose of this study was to compare sedated versus unsedated GI endoscopy regarding cost, safety, degree of comfort, tolerance ...
Combs C Andrew - - 2013
To compare intra-amniotic inflammation versus microbial invasion of the amniotic cavity (MIAC) as predictors of adverse outcome in preterm labor with intact membranes. Interleukin-6 (IL-6) was measured in prospectively collected amniotic fluid from 305 women with preterm labor. MIAC was defined by amniotic fluid culture and/or detection of microbial 16S ...
Ansari Daniel - - 2013
Abstract Objective. Previous studies have identified a significant volume-outcome relationship for hospitals performing pancreaticoduodenectomy (PD). However, scant information exists concerning the effects of increased caseload of PD within the same hospital. Here, we describe the effects of becoming a high-volume provider of PD. Material and methods. The study group comprised ...
Pelavski A - - 2013
Background: Nonagenarian people are increasingly using the emergency services, however, few studies have addressed this population. The goal of this prospective observational study is to determine relevant factors that independently reduce their immediate postoperative and mid-term survival. Methods: We included all the nonagenarians who underwent non-traumatic emergency surgery between 2006-2011. ...
Bjerke-Kroll Benjamin T BT Hospital for Special Surgery, New York, New - - 2013
In a consecutive series of 536 unilateral primary total hip arthroplasties (THAs) and 598 unilateral primary total knee arthroplasties (TKAs), the use of a post-operative drain was associated with $538 additional cost per THA, and $455 for TKA. The use of a drain increased hospital length of stay (LOS) for ...
Myers Robert P - - 2013
Modifications to the Model for End-Stage Liver Disease (MELD) have been proposed to improve prioritization of liver transplant (LT) candidates. Using a U.S. database, we derived a revised MELD including sodium and albumin [5-variable MELD (5vMELD)] that improved prediction of waiting list mortality. Our objectives were to confirm the association ...
Kwatra Gagandeep - - 2013
Aim: We aimed to study the cost of stroke, its predictors, and the impact on social determinants of the family. Settings and Design: This prospective study was done in the Stroke unit and Neurology clinic between April 2009 and October 2011. Materials and Methods: All first ever stroke patients during ...
Kaneko Tsuyoshi - - 2013
Reoperative aortic valve replacement (re-AVR) in octogenarians is considered high risk and therefore might be indicated for transcatheter AVR. The minimally invasive technique for re-AVR limits dissection and might benefit this patient population. We report the outcomes of re-AVR in high-risk octogenarians who might be considered candidates for transcatheter AVR ...
Avramovski P - - 2013
Abstract Background/Aims: The aim of this study was to investigate all-cause and cardiovascular mortality in chronic hemodialysis patients (CHP) and to identify the determinants of mortality predictors. Methods: In this study with 3 years of follow-up period, we studied a cohort of 80 CHPs. Mean age at entry was 59.3 ± 11.8 ...
Chua Paul Y - - 2013
To investigate the effect of socioeconomic deprivation on cornea graft survival in the United Kingdom. Retrospective cohort study. All the recipients (n = 13 644) undergoing their first penetrating keratoplasty (PK) registered on the United Kingdom Transplant Registry between April 1999 and March 2011 were included. Data of patients' demographic details, indications, ...
Sudan Ranjan - - 2013
Ethnic disparities in patterns of utilization and outcomes after Roux-en-Y gastric bypass surgery (RYGB) were examined from Bariatric Outcomes Longitudinal Database. Descriptive statistics were used for demographics of Whites, Blacks, or Hispanics undergoing RYGB with 1 year of follow-up, between June 2007 and October 2011. Multivariate logistic and normal regression models, ...
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