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Sebag Frédéric A FA Department of Cardiology, Henri Mondor Hospital (Assistance Publique-Hôpitaux de Paris), Creteil, - - 2014
To evaluate the prognostic impact of QRS width in patients with low-flow/low-gradient aortic stenosis (LF/LGAS). Among 88 consecutive patients referred to our institution for LF/LGAS from September 1994 to March 2007, baseline demographic, clinical, echocardiographic, and electrocardiographic data were collected. This population was divided into two groups according to baseline ...
Tuttle John R JR Department of Orthopaedics, Brown University Alpert School of Medicine, Providence, Rhode - - 2014
The purpose of this study was to provide a cost-benefit analysis of topical tranexamic acid (TXA) in primary total hip and knee arthroplasty patients. A retrospective cohort of 591 consecutive patients, 311 experimental and 280 control, revealed a transfusion rate reduction from 17.5% to 5.5%, increased postoperative hemoglobin, and decreased ...
Rollins K E KE Cambridge Vascular Unit, Box 201, Level 6, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, CB2 0QQ, - - 2014
Emergency endovascular repair (EVAR) for ruptured abdominal aortic aneurysm (rAAA) may have lower operative mortality rates than open surgical repair. Concerns remain that the early survival benefit after EVAR for rAAA may be offset by late reinterventions. The aim of this study was to compare reintervention rates and cost-effectiveness of ...
Lalmohamed Arief A Utrecht University and University Medical Center Utrecht, Utrecht, The - - 2014
Total hip arthroplasty (THA) and total knee arthroplasty (TKA) are effective procedures for patients with moderate-to-severe osteoarthritis. Mortality rates after THA and TKA may have changed because of new surgical techniques, improvement of peri- and postoperative care, and performance of surgery in older patients having multiple comorbidities. However, data on ...
Carrasco-Chinchilla Fernando F Unidad del Corazón, Hospital Clínico Universitario Virgen de la Victoria, Málaga, Spain. Electronic address: - - 2014
Mortality from left-sided infective endocarditis remains very high. The aim of this study was to assess the impact of a multidisciplinary alert strategy (AMULTEI), based on clinical, echocardiographic and microbiological findings, implemented in 2008 in a tertiary hospital. Cohort study comparing our historical data series (1996-2007) with the number of ...
Johnson Matthew S MS Department of Otolaryngology, University of Nebraska Medical Center, Omaha, Nebraska, - - 2014
To evaluate the utility of a modified frailty index as an indicator of postoperative mortality in patients undergoing tracheostomy. Case series with chart review. Tertiary care veterans hospital. A chart review was conducted of consecutive tracheostomies performed between April 2007 and September 2012. A modified frailty index consisting of 11 ...
Blanchette Lisa M LM Lisa M. Blanchette, Pharm.D., is Infectious Diseases Clinical Pharmacy Specialist, Novant Health Presbyterian Medical Center, Charlotte, NC. Paul Huiras, Pharm.D., BCPS, is Surgical Intensive Care Unit Clinical Pharmacy Specialist; and Stella Papadopoulos, Pharm.D., BCPS, is Administrative Director, Clinical and Academic Affairs, Boston Medical Center, Boston, - - 2014
Results of a study comparing clinical and cost outcomes with the use of standardized versus custom-prepared parenteral nutrition (PN) in an acute care setting are reported. In a retrospective pre-post analysis, nutritional target attainment, electrolyte abnormalities, and other outcomes were compared in patients 15 years of age or older who ...
Satrom Katie K Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA and Department of Energy Management, University of Minnesota, Minneapolis, MN, - - 2014
Neonatal hyperbilirubinemia continues to be a leading cause of morbidity and mortality in resource-limited countries. The aim of this study was to measure the effectiveness of existing phototherapy units at a local hospital in Cameroon using an irradiance meter. Phototherapy units (n = 4) in one newborn nursery in Cameroon ...
Kissin Dmitry M DM Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia; and the Center for Human Reproduction, New York, New - - 2014
To assess the association between number of embryos transferred and a measure of assisted reproductive technology success that emphasizes good perinatal outcome. We analyzed assisted reproductive technology cycles initiated in 2011 that progressed to fresh embryo transfer among women using autologous oocytes and reported to the U.S. National Assisted Reproductive ...
Liu Yi Y 1] CAS Key Laboratory of Crust-Mantle Materials and Environments, School of Earth and Space Sciences, University of Science and Technology of China, Hefei 230026, China - - 2014
A large and sudden increase in radiocarbon ((14)C) around AD 773 are documented in coral skeletons from the South China Sea. The (14)C increased by ~ 15‰ during winter, and remain elevated for more than 4 months, then increased and dropped down within two months, forming a spike of 45‰ ...
Leboeuf-Yde Charlotte C Research Department, The Spine Center of Southern Denmark, Hospital Lillebælt and Institute of Regional Health Research, University of Southern Denmark, Østre Hougvej 55, DK5500 Middelfart, Denmark. - - 2014
Over one year, the majority of patients with low back pain (LBP) from the secondary care sector could not report a single week without LBP and few could report a non-episode, defined as at least one month without LBP. Presumably, non-episodes would be more common in the general population. The ...
Pozzi M M Division of Cardiac Surgery, Pitié-Salpêtrière Hospital, University "Pierre et Marie Curie", Paris, France; Ph.D. School in Cardiovascular Science, Cardiovascular Surgery Unit, University of Verona Medical School, Verona, Italy. Electronic address: - - 2014
Heart retransplantation (HRT) accounts for 2.6% of heart transplantation (HT) indications. We performed a retrospective analysis of our recent HRT experience. From January 2000 to June 2012, 820 HTs were performed; 798 (97.3%) were primary HTs and 21 (2.5%) 2nd HTs. Indications for HRT included: 57% cardiac allograft vasculopathy, 33% ...
Aleme Adisu A Amhara Regional state Health Bureau, - - 2014
Understanding the feasibility of achieving widespread coverage with Insecticide-Treated Nets has to be preceded by learning how people value the Insecticide-Treated Nets and estimating the potential demand and willingness to pay so that sustainability of the intervention can be assured. The objective of this study was to determine willingness to ...
Ingle Lee L 0000-0001-6155-5577 Department of Sport, Health & Exercise Science, University of Hull, 104 Don Building, Cottingham Road, Kingston upon Hull, HU7 6RX, - - 2014
Background. The 6-minute walk test (6-MWT) is used to assess patients with chronic heart failure (CHF). The prognostic significance of the 6-MWT distance during long-term followup (>5 years) is unclear. Methods. 1,667 patients (median [inter-quartile range, IQR]) (age 72 [65-77]; 75% males) with heart failure due to left ventricular systolic ...
Champunot Ratapum - - 2014
To assess the cost effectiveness of an initial ICU admissionforpatients with severe sepsis or those in septic shock following the initial resuscitation in the emergency department. Mortality data was generated through retrospective data obtained from 1,048 adult patients with severe sepsis or in septic shock from one tertiary care and ...
Sato Takuya - - 2014
The aim of this study was to assess the outcome of salvage esophagectomy with less extensive lymphadenectomy, which we have performed since 2003 to improve high mortality and morbidity of standard salvage esophagectomy. We retrospectively compared the surgical outcome of 15 patients who underwent standard salvage esophagectomy via right thoracotomy ...
Rowińska-Zakrzewska Ewa E - - 2014
In 2012 the incidence rate of tuberculosis in Poland was 19.6/100,000 but these was great variability between regions concerning notification rates (from 10.9/100,000 to 30.2/100,000). The aim of the study was to assess whether there are elements that might confirm that these differences are true. To answer this question, we ...
Thomas Dustin M DM Cardiology Service MCHE-MDC, Brooke Army Medical Center, 3551 Roger Brooke Drive, San Antonio, TX 78234-6200, - - 2014
Background. We evaluated the incidence of mortality and myocardial infarction (MI) in endovascular repair (EVAR) as compared to open aneurysm repair (OAR) in both elective and ruptured abdominal aortic aneurysm (AAA ) setting. Methods. We analyzed the rates of 30-day mortality, 30-day MI, and hospital length of stay (LOS) based ...
Noreikaitė Aurelija A Institute of Physiology and Pharmacology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania. Electronic address: - - 2014
The aim of this study was to identify a cyclosporine therapeutic range for kidney recipients. The cyclosporine exposure level was based on the calculation of the mean area under the concentration-time curve AUC(0-12). The AUC(0-12) was estimated using a Bayesian estimator and a 3-point limited sampling strategy. Cyclosporine exposure levels ...
Blackman Daniel J DJ Department of Cardiology, Leeds Teaching Hospitals, Leeds, - - 2013
To determine whether outcomes from transcatheter aortic valve implantation (TAVI) vary according to access route and valve type in a real-world population. Registry and uncontrolled trial data have found that patients undergoing nonfemoral TAVI have higher early and late mortality. It is not clear whether worse outcomes relate directly to ...
Turney Eric J EJ Department of Vascular Surgery, Cleveland Clinic Lerner College of Medicine at Case Western Reserve University, Cleveland, - - 2013
With more than a decade of use of endovascular aneurysm repair (EVAR), we expect to see a rise in the number of failing endografts. We review a single-center experience with EVAR explants to identify patterns of presentation and understand operative outcomes that may alter clinical management. A retrospective analysis of ...
Nishida Takahiro T Department of Cardiovascular Surgery, Kyushu University Graduate School of Medical Sciences, Fukuoka, - - 2013
The European System for Cardiac Operative Risk Evaluation (EuroSCORE) II was developed to improve the overestimation of surgical risk associated with the original (additive and logistic) EuroSCOREs. The purpose of this study was to evaluate the significance of the EuroSCORE II by comparing its performance with that of the original ...
Ambler Graeme K GK Department of Vascular Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom. Electronic address: - - 2013
Critical limb ischemia (CLI) is a common condition associated with high levels of morbidity and mortality. Most work to date has focused on surgeon-oriented outcomes such as patency, but there is increasing interest in patient-oriented outcomes such as mobility and independence. This study was conducted to determine the effect of ...
Banerjee Amitava - - 2013
ABSTRACT BACKGROUND Patients with chronic kidney disease (CKD) are more likely to develop atrial fibrillation(AF) than individuals with normal renal function, and are more likely to suffer ischaemic stroke(IS)/thromboembolism(TE). No prior study has considered the impact of eGFR on bleeding. We investigated the relationship of eGFR to IS/TE, mortality and ...
Chandrasegaram Manju D MD HPB Department, Flinders Medical Centre, Adelaide, SA, Australia; Department of Surgery, The University of Sydney, Sydney Medical School, Nepean, Penrith, NSW, - - 2013
Portal vein (PV) resection is used increasingly in pancreatic resections. There is no agreed policy regarding anticoagulation. A systematic review was performed to compare studies with an anticoagulation policy (AC+) to no anticoagulation policy (AC-) after venous resection. There were eight AC+ studies (n = 266) and five AC- studies ...
Lalmohamed Arief A Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute of Pharmaceutical Sciences, Utrecht, Netherlands; Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht, - - 2013
Introduction: THR / TKR surgery are effective procedures for patients with moderate-to-severe osteoarthritis. Mortality rates after THR and TKR may have changed because of new surgical techniques, improvement of peri- and postoperative care, and patients having more comorbidity. Data on secular mortality trends are however scarce. The objective was to ...
Zhao Yang Y Eli Lilly and Company, 893S. Delaware St., Indianapolis, IN, 46285, USA. Electronic address: - - 2013
This study examined the association between teriparatide (TPTD) adherence, and healthcare utilization and costs among hip fracture (HFx) patients. Individuals aged 50years and older with an HFx between 1/1/2002-12/31/2010 were identified from a large US administrative claims database. The first HFx date during this period was designated as the index. ...
Cohen S - - 2013
Background/Objective:To assess the conclusiveness of the Cochrane Reviews (CRs) in the field of Nutrition, we tested the hypotheses that: (1) the majority of CRs is inconclusive; (2) the majority of CRs recognizes the need for further and better studies and (3) the ability to reach a conclusion is dependent on ...
Lane Jordan D - - 2013
Object Antibiotic-impregnated shunts have yet to find widespread use in the developing world, largely due to cost. Given potential differences in the microbial spectrum, their effectiveness in preventing shunt infection for populations in low-income countries may differ and has not been demonstrated. This study is the first to compare the ...
Riera M - - 2013
A study was made to explore the possible association between the perioperative transfusion of 1 - 2 red blood cell units and in-hospital morbidity, 30-day mortality, and long-term survival in patients undergoing heart surgery. A prospective observational study was carried out. The ICU of a university hospital. All patients over ...
Wang Hong-Ling HL Department of Gastroenterology, the Research Center for Clinical Study of Intestinal & Colorectal Diseases of Hubei Province, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China, - - 2013
National data show that in China mainland unsedated gastrointestinal (GI) endoscopy has been applied in most hospitals for clinical examination, while sedated GI endoscopy is only performed in some hospitals. The purpose of this study was to compare sedated versus unsedated GI endoscopy regarding cost, safety, degree of comfort, tolerance ...
Combs C Andrew - - 2013
To compare intra-amniotic inflammation versus microbial invasion of the amniotic cavity (MIAC) as predictors of adverse outcome in preterm labor with intact membranes. Interleukin-6 (IL-6) was measured in prospectively collected amniotic fluid from 305 women with preterm labor. MIAC was defined by amniotic fluid culture and/or detection of microbial 16S ...
Ansari Daniel - - 2013
Abstract Objective. Previous studies have identified a significant volume-outcome relationship for hospitals performing pancreaticoduodenectomy (PD). However, scant information exists concerning the effects of increased caseload of PD within the same hospital. Here, we describe the effects of becoming a high-volume provider of PD. Material and methods. The study group comprised ...
Pelavski A - - 2013
Background: Nonagenarian people are increasingly using the emergency services, however, few studies have addressed this population. The goal of this prospective observational study is to determine relevant factors that independently reduce their immediate postoperative and mid-term survival. Methods: We included all the nonagenarians who underwent non-traumatic emergency surgery between 2006-2011. ...
Bjerke-Kroll Benjamin T BT Hospital for Special Surgery, New York, New - - 2013
In a consecutive series of 536 unilateral primary total hip arthroplasties (THAs) and 598 unilateral primary total knee arthroplasties (TKAs), the use of a post-operative drain was associated with $538 additional cost per THA, and $455 for TKA. The use of a drain increased hospital length of stay (LOS) for ...
Myers Robert P - - 2013
Modifications to the Model for End-Stage Liver Disease (MELD) have been proposed to improve prioritization of liver transplant (LT) candidates. Using a U.S. database, we derived a revised MELD including sodium and albumin [5-variable MELD (5vMELD)] that improved prediction of waiting list mortality. Our objectives were to confirm the association ...
Kwatra Gagandeep - - 2013
Aim: We aimed to study the cost of stroke, its predictors, and the impact on social determinants of the family. Settings and Design: This prospective study was done in the Stroke unit and Neurology clinic between April 2009 and October 2011. Materials and Methods: All first ever stroke patients during ...
Kaneko Tsuyoshi - - 2013
Reoperative aortic valve replacement (re-AVR) in octogenarians is considered high risk and therefore might be indicated for transcatheter AVR. The minimally invasive technique for re-AVR limits dissection and might benefit this patient population. We report the outcomes of re-AVR in high-risk octogenarians who might be considered candidates for transcatheter AVR ...
Avramovski P - - 2013
Abstract Background/Aims: The aim of this study was to investigate all-cause and cardiovascular mortality in chronic hemodialysis patients (CHP) and to identify the determinants of mortality predictors. Methods: In this study with 3 years of follow-up period, we studied a cohort of 80 CHPs. Mean age at entry was 59.3 ± 11.8 ...
Chua Paul Y - - 2013
To investigate the effect of socioeconomic deprivation on cornea graft survival in the United Kingdom. Retrospective cohort study. All the recipients (n = 13 644) undergoing their first penetrating keratoplasty (PK) registered on the United Kingdom Transplant Registry between April 1999 and March 2011 were included. Data of patients' demographic details, indications, ...
Sudan Ranjan - - 2013
Ethnic disparities in patterns of utilization and outcomes after Roux-en-Y gastric bypass surgery (RYGB) were examined from Bariatric Outcomes Longitudinal Database. Descriptive statistics were used for demographics of Whites, Blacks, or Hispanics undergoing RYGB with 1 year of follow-up, between June 2007 and October 2011. Multivariate logistic and normal regression models, ...
Aksoy Olcay - - 2013
Assessment of patients with aortic stenosis (AS) and impaired left ventricular function remains challenging. Aortic valve calcium (AVC) scoring with computed tomography (CT) and fluoroscopy has been proposed as means of diagnosing and predicting outcomes in patients with severe AS. Severity of aortic valve calcification correlates with the diagnosis of ...
Paone Gaetano - - 2013
This study examined the relationship between transfusion of 1 or 2 units of red blood cells (RBCs) and the risk of morbidity and mortality after isolated on-pump coronary artery bypass grafting (CABG). A total of 22,785 consecutive patients underwent isolated on-pump CABG between January 1, 2008, and December 31, 2011 ...
Abbass Mohammad Ali - - 2013
Although the safety of hepatic resection has improved, it is still a highly morbid procedure. A retrospective cohort of 375 patients undergoing hepatectomy (2004 to 2012) was done. All procedures were performed by a single surgeon at a tertiary center. To help identify trends over time, two subgroups were identified: ...
Doussau Adélaïde - - 2013
During on-pump cardiac surgery, hemorrhagic complications occur frequently. Fresh-frozen plasma (FFP) is widely transfused to provide coagulation factors. Yet, no randomized clinical trial has demonstrated its benefits on mortality. We assessed the relationship between therapeutic transfusion of FFP and 30-day mortality in cardiac surgery patients suffering from excessive bleeding in ...
Azab Basem - - 2013
Neutrophil lymphocyte ratio (NLR) is a predictor of major adverse cardiovascular outcomes. Our study explores the value of NLR in predicting long-term mortality after minimally invasive coronary artery bypass surgery (MICS) via lateral left-thoracotomy versus conventional sternotomy coronary artery bypass grafting (CABG) surgery. A total of 1126 consecutive patients (729 ...
Ohkura Yasuo Y Department of Hepatobiliary-Pancreatic and Transplant Surgery, Mie University School of Medicine, Tsu, Mie, - - 2013
The aim of this study was to evaluate the benefit of technetium-99m galactosyl human serum albumin ((99m) Tc-GSA) scintigraphy instead of the indocyanine green retention rate at 15 min (ICGR15) in the patients scheduled for hepatectomy, paying special attention to the factors causing the discrepancy between the ICGR15 and the hepatic ...
Singh Jasvinder A - - 2013
To examine whether racial disparities in usage and outcomes of total knee and total hip arthroplasty (TKA and THA) have declined over time. We used data from the US Medicare Program (MedPAR data) for years 1991-2008 to identify four separate cohorts of patients (primary TKA, revision TKA, primary THA, revision ...
Tanoue Yoshihisa - - 2013
The operative validity of aortic valve replacement (AVR) for high-risk patients with impaired left ventricular (LV) function is controversial. We measured LV contractility, afterload, and efficiency by use of transthoracic echocardiography data obtained before, after, and approximately 1 year after isolated AVR for 335 patients with aortic stenosis (AS group; n = 160), ...
Richardson Arthur J - - 2013
There is an inverse relationship between hospital and surgeon volume and mortality in many types of complex surgery. The aim of this paper is to investigate the volume effect on outcomes of liver surgery. A systematic review and meta-analysis was performed. A literature search was conducted using Medline and EMBASE ...
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