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Mora-Soler A - - 2014
Background: the duodenum is the most common location for ectopic varices. Bleeding is rare, but when it appears, it is massive and difficult to control.Material and methods: retrospective description of five clinical cases of digestive bleeding secondary to duodenal varices that we observed between the years 2011 and 2012, together ...
Navas-López V M - - 2014
Objectives: to describe the efficacy and safety of adalimumab (ADA) in inducing clinical remission and reducing inflammation of intestinal mucosa in children with Crohn´s disease (CD).Methods: we carried out a descriptive, observational study with all patients diagnosed with CD and treated with ADA between January 2007 and March 2013. Disease ...
Galvão Violeta Régnier VR Division of Clinical Immunology and Allergy, University of São Paulo Medical School, Rua Doutor Bacelar, 747 ap 81, Vila Clementino, 04026-001, São Paulo, SP, Brazil, - - 2014
Perioperative anaphylaxis is a life-threatening condition with an estimated prevalence of 1:3,500 to 1:20,000 procedures and a mortality rate of up to 9 %. Clinical presentation involves signs such as skin rash, urticaria, angioedema, bronchospasm, tachycardia, bradycardia, and hypotension. Prompt recognition and treatment is of utmost importance to the patient's prognosis, ...
Saulyte Trakymiene Sonata S Faculty of Medicine, Vilnius University, Vilnius, Lithuania; Centre for Pediatric Hematology/Oncology, Children's Hospital, Affiliate of Vilnius University Hospital Santariskiu Klinikos, Vilnius, - - 2014
There are two main modes of replacement therapy for haemophilia patients: either to stop bleeding (on-demand) or regular infusions of clotting factor to prevent bleeds (prophylaxis). Fifty yr of clinical experience have provided evidence of the superiority of prophylaxis by showing a reduction in bleeds and development of arthropathy. Prophylaxis has ...
Cestaro G G Unit of General Specialistic and Mini‑invasive Surgery Federico II University of Naples, Naples, Italy - - - 2014
This prospective study was done to evaluate the efficacy of commercial fibrin glue application in the healing of patients with fistulas-in-ano from a short follow up period (one year). This randomized clinical trial of 26 patients was performed during the period from January 2012 to July 2012. Nineteen men and ...
Liang W T WT Department of Vascular Surgery Xuanwu Hospital, Capital Medical University Xicheng District, Beijing, P. R. China - - - 2014
Laparoscopic Nissen fundoplication (LNF) and Stretta radiofrequency (RF) are used as main alternative strategies to manage medication-refractory GERD. This study was therefore prospectively evaluated outcomes of patients with refractory GERD 5 years after LNF or Stretta RF. A total of 215 consecutive patients with refractory GERD underwent LNF (N.=102) and ...
Arimoto Atsushi A Department of Ophthalmology, Kanazawa Medical University, Ishikawa, - - 2014
The aim of this study was to investigate the efficacy of 2% rebamipide suspension in treatment of keratoconjunctivitis sicca (KCS) in patients with Sjögren syndrome (SS) with or without punctal occlusions. Thirty patients with SS, diagnosed based on the presence of autoantibodies and/or focus score >1 on lip biopsies, with ...
Gungor Ugurlucan F F Department of Obstetrics and Gynecology Division of Urogynecology, Istanbul University Istanbul Medical School, Istanbul, Turkey - - - 2014
Aim of the study was to compare the effects of outpatient clinic-based versus home-based intravaginal electrical stimulation (ES) for the treatment of urinary incontinence. Women applying with the complaint of urinary incontinence and offered ES treatment were divided into outpatient clinic-based or home-based ES. Patients were instructed about home-based ES ...
Xing Shuxing S Second Department of Orthopedics, Ürümqi General Hospital, Lanzhou Command, Ürümqi, Xinjiang 830000, P.R. - - 2014
The aim of the present study was to investigate the effects of various decellularization methods on the histological and biomechanical properties of rabbit tendons. In total, six chemical reagents, including 1% t-octyl-phenoxypolyethoxyethanol (Triton-X 100), 0.5% sodium dodecyl sulfate (SDS), 1% tri-n-butyl phosphate (TnBP), 1% Triton-X 100 + 0.5% SDS, 1% ...
Pierce John Thomas - - 2014
Traditionally, microvascular decompression (MVD) for treating trigeminal neuralgia (TN) has been performed using a microscope. Endoscopic microvascular decompression (E-MVD) is a newly accepted variation of this procedure. The endoscope improves the field of vision, and facilitates an easier dissection and placement of Teflon. It provides the advantage of better visualizing ...
Smith Justin S - - 2014
Adults with spinal deformity present with pain and disability. Our objective was to compare outcomes for op and nonop treatment for adult spinal deformity (ASD) based on a prospective, multicenter patient population. Multicenter, prospective analysis of consecutive ASD patients. Inclusion criteria: age >18 year and ASD. Propensity scores were used ...
Yang Wuyang - - 2014
Previous studies have suggested that deep and posterior fossa locations are associated with propensity to hemorrhage and poor functional outcomes in brain arteriovenous malformation (AVM) patients. Few studies have stratified risks within these locations. We therefore sought to clarify hemorrhage risk and functional outcome variations in AVMs that share the ...
Rodrigues Tiago T Departamento de Neurorradiologia, Hospital de Santo António, Centro Hospitalar do Poro, Largo Prof. Abel Salazar, 4099-001, Porto, Portugal, - - 2014
To report the epidemiological features, clinical presentation, angiographic characteristics and therapeutic options, success and complication rates in patients with dural carotid cavernous fistulas (dural CCFs). Retrospective evaluation of patients followed in our institution between January of 2005 and September of 2013. There were 38 patients, 76 % females, with an average ...
Ortmaier Reinhold R Unfallchirurgie und Sporttraumatologie, Paracelsus medizinische Universität, Salzburg, Austria, - - 2014
We set out to compare osteosynthesis using the minimally invasive, semi-rigid, Humerusblock to reverse shoulder arthroplasty (RSA) for primary fracture treatment in three- and four-part fractures in patients over 65 years old. In the study period from 2008 to 2011, we conducted a matched-pair analysis of 25 patients treated with ...
Souteyrand Geraud G Department of Cardiology, Clermont-Ferrand University Hospital, Clermont-Ferrand, - - 2014
Aims: To assess whether a strategy of invasive management without stents in selected acute coronary syndrome (ACS) patients with a large thrombus burden (LTB) might be feasible and safe. Methods and results: We performed a prospective non-randomised observational cohort study of invasive treatment decisions guided by optical coherence tomography (OCT) ...
Bektas Hüseyin H Clinic for General, Visceral and Transplant Surgery, Medical University of Hannover, 30625, Hannover, - - 2014
This randomized, controlled, single-blinded multicenter study evaluated the efficacy of latest-generation fibrin sealant containing synthetic aprotinin as fibrinolysis inhibitor as supportive treatment for hemostasis after elective partial hepatectomy. Adult subjects undergoing resection of at least one liver segment were assigned to treatment with fibrin sealant or manual compression with a ...
Payette Alexis - - 2014
Context: Hemoperfusion (HP) or dialysis is occasionally used following carbamazepine (CBZ) toxicity but it remains unclear which is the most efficient modality. We describe a case of severe CBZ intoxication treated with different extracorporeal modalities during which CBZ toxicokinetics were compared. Case details: A 58-year-old man was transferred to our ...
Kim Bum Joon BJ Departments of Radiology - - 2014
Object Endovascular procedures are one of the important treatment options for steno-occlusive arteries in ischemic stroke patients. However, embolic complications after such procedures are always a concern. The authors investigated the association between serial change of residual platelet reactivity and silent embolic cerebral infarction (SECI) after endovascular treatment. Methods Ischemic ...
Nayak Atul A Department of Chemical Engineering, Loughborough University , Loughborough , - - 2014
Abstract A study that combines microneedles (MNs) and sonophoresis pre-treatment was explored to determine their combined effects on percutaneous delivery of lidocaine from a polymeric hydrogel formulation. Varying ratios of carboxymethylcellulose and gelatine (NaCMC/gel ranges 1:1.60-1:2.66) loaded with lidocaine were prepared and characterized for zeta potential and particle size. Additionally, ...
Wiman Eriksson Eva E Department of Dental Sleep Medicine, Postgraduate Dental Education Center, Örebro, - - 2014
This 10-year follow-up prospective study aimed to evaluate the effects of treatment with a mandibular protruding device (MPD) on respiratory parameters and subjective symptoms in patients with obstructive sleep apnea (OSA) or snoring. Seventy-seven consecutive patients diagnosed with OSA or snoring were treated with an MPD. At baseline and the ...
Frazzitta Giuseppe G "Moriggia-Pelascini" Hospital, Gravedona ed Uniti, Italy Fondazione Europea Ricerca Biomedica FERB, "S. Isidoro" Hospital, Trescore Balneario, Italy - - 2014
Background. Although physical exercise improves motor aspects of Parkinson's disease (PD), it is not clear whether it may also have a neuroprotective effect. Objective. In this 2-year follow-up study, we determined whether intensive exercise in the early stages of the disease slows down PD progression. Methods. Forty newly diagnosed patients ...
Arduc Ayse A From the *Department of Endocrinology and Metabolism, Ministry of Health, Ankara Numune Research and Training Hospital, Ankara, Turkey; †National Institute of Diabetes and Digestive and Kidney Diseases, Diabetes, Endocrine and Obesity Branch, National Institutes of Health, Bethesda, Maryland; ‡Faculty of Medicine, Department of Internal Medicine, Duzce University, Duzce, Turkey; §Department of Nuclear Medicine, Ministry of Health, Ankara Numune Research and Training Hospital, Ankara, Turkey; and ¶Faculty of Medicine, Department of Endocrinology and Metabolism, Hitit University, Corum, - - 2014
Radioactive Iodine therapy (RAIT) plays a major role in the treatment of hyperthyroidism. In addition to the thyroid gland, significant amounts of radioactive iodine are maintained in the stomach. The aim of this study was to determine if RAIT has any effect on Helicobacter pylori infection, based on the C ...
Gifford Paul - - 2014
To investigate changes to corneal surface aberrations and vision between PresbyLASIK and LASIK for correction of presbyopia using the MEL 80 platform (Carl Zeiss Meditec, Jena, Germany). The retrospective data of 31 patients who underwent PresbyLASIK (the PresbyLASIK group) between January 2009 and November 2011 and 20 matched patients who ...
Meyborg M M Division of Vascular Medicine, Department of Cardiovascular Medicine, Münster, Germany - - - 2014
Recanalization of long segmental occlusions of femoropopliteal arteries can be achieved by angioplasty and implantation of nitinol stents with high procedural success rates. However, due to recurrent in--stent restenoses (ISR) some patients need repeated interventions and their intermediate success rates are uncertain. Patients who were treated in our center from ...
De Rui M M Department of Medicine DIMED, Geriatrics Division, University of Padova, Italy - - - 2014
The high cost of cholinesterase inhibitors (ChEIs) makes it crucial for the clinician to accurately identify subjects who will benefit from treatment. In Italy ChEI efficacy is assessed after 3 months, but this time interval may not be enough to know whether to continue or abandon the treatment. The aim ...
Sedivá Lucie L Department of Cardiology, Na Homolce Hospital, Roentgenova 2, Prague 5 150 30, Czech Republic - - 2014
Durable isolation of the pulmonary veins (PVs) remains the cornerstone of treatment for paroxysmal atrial fibrillation (PAF) and is also used in the treatment of some patients with persistent atrial fibrillation. Visually guided laser ablation (VGLA) has been proven to be safe and effective as a treatment for atrial fibrillation ...
Uyeturk Ugur U Abant Izzet Baysal University Faculty of Medicine, Department Of Urology , A.I.B.U. Uroloji Bolu , Bolu, Turkey , 14000 ; - - 2014
Objective:Mitomycin C (MMC), bevacizumab, and 5-fluorouracil (5-FU) are frequently used in cancer treatment. Each of these agents also exhibits antiproliferative properties in different tissues. We compared the efficacy of MMC, bevacizumab, and 5-FU for the prevention of urethral stricture (US). Materials and Methods: Forty male rabbits with traumatized urethras were ...
Ziemlewicz Timothy J TJ Department of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, E3/366, Madison, WI, 53792-3252, USA, - - 2014
This study was designed to explore the safety and efficacy of percutaneous microwave (MW) ablation as an alternative treatment for symptomatic giant hepatic hemangiomas. Patients (n = 7; 6 females, 1 male; mean age = 44 years) with symptomatic, giant hemangiomas (n = 8) were treated with ultrasound-guided percutaneous MW ablation and followed for a mean of ...
Dos Santos Aretha Aliny Ramos AA a Master's student, Graduate Program in Dentistry, Federal University of Paraíba, João Pessoa, PB, - - 2014
Abstract Objective: To test the hypothesis that treatment time, debris/biofilm, and oral pH have an influence on the physical-chemical properties of orthodontic brackets and arch wires. Materials and Methods: One hundred twenty metal brackets were evaluated. They were divided into four groups (n  =  30) according to treatment time: group ...
Turk Aquilla S AS Department of Radiology and Radiological Sciences, Medical University of South Carolina, Charleston, South Carolina, - - 2014
The use of mechanical thrombectomy for the treatment of acute ischemic stroke has significantly advanced over the last 5 years. Few data are available comparing the cost and clinical and angiographic outcomes associated with available techniques. The aim of this study is to compare the cost and efficacy of current endovascular ...
Lee Young-Jun YJ From the Department of Medical Imaging (Y.-J.L., K.G.T., G.S., T.K.), and Division of Neurosurgery (T.K.), Toronto Western Hospital, University of Toronto, Ontario, Canada; Department of Radiology, Hanyang University Hospital, Hanyang University College of Medicine, Seoul, Korea (Y.-J.L.); and Service de Neuroradiologie, CHU Bicêtre, Le Kremlin Bicêtre Cedex, France - - 2014
As a result of the rarity of spinal cord arteriovenous malformations (AVM), there are only a few series available that describe clinical features, outcome after treatment, and natural history of these lesions. In this article, we aim to describe our experience with both nidus- and fistulous-type spinal cord AVMs. Forty-four ...
Song In-Ho IH From the Department of Rheumatology and the Department of Radiology, Charité Medical University, Campus Charité Mitte, Berlin; German Rheumatism Research Center, Berlin, Germany; Division of Rheumatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Pfizer; Schlosspark-Klinik; Endokrinologikum, Berlin, Germany. Supported by an unrestricted grant from Pfizer. Pfizer provided financial support and provided the study drug etanercept. I-H. Song, Rheumatology, Charité Medical University; K-G. Hermann, Department of Radiology, Charité Medical University; H. Haibel, Rheumatology, Charité Medical University; C.E. Althoff, Department of Radiology, Charité Medical University; D. Poddubnyy, Rheumatology, Charité Medical University; J. Listing; A. Weiß, German Rheumatism Research Center; B. Buß, Rheumatology, Charité Medical University; B. Freundlich, Division of Rheumatology, University of Pennsylvania; E. Lange, Pfizer; R. Alten, Schlosspark-Klinik; M. Rudwaleit, Rheumatology, Charité Medical University, and Endokrinologikum; J. Sieper, Rheumatology, Charité Medical University. Address correspondence to Dr. J. Sieper, Charité, Campus Benjamin Franklin, Med. Clinic I, Rheumatology, Hindenburgdamm 30, 12203 Berlin, Germany. E-mail: joachim.sieper@charite.de. Accepted for publication May 15, - - 2014
In patients with early active axial spondyloarthritis (axSpA) with a disease duration of < 5 years, the longterm efficacy of 3 years of continuous etanercept (ETN) treatment was assessed. In a previously reported ESTHER trial, patients with axSpA were randomized to treatment with ETN (n = 40) versus sulfasalazine (SSZ; ...
Takamura Yoshihiro Y Ophthalmology, University of Fukui, 23-3 Matsuoka, Eiheiji-cho, Yoshida-gun, Fukui, 910-1193, Japan - - 2014
Purpose:This study aimed to investigate whether targeted retinal photocoagulation (TRP) for non-perfusion areas (NPAs) could have preventive effect for the recurrence of diabetic macular edema (DME) after intravitreal injection of bevacizumab (IVB). Methods:Eyes in the IVB group received 1.25 mg IVB and eyes in the IVB+TRP group received 1.25 mg ...
Metelmann Hans-Robert HR Department of Oral and Maxillofacial Surgery/Plastic Surgery, Medical School, Greifswald University, Greifswald, - - 2014
The acceleration of wound healing is a major surgical concern. A triterpene extract from birch bark (Betulae cortex) experimentally enhances keratinocyte differentiation in vitro and accelerates wound healing ex vivo. We conducted an open, blind-evaluated, controlled, prospective, randomized (1:1) phase II clinical trial in patients requiring split-thickness skin graft transplantation ...
Collet Jean-Philippe JP ACTION Study Group, Institut de Cardiologie Hôpital Pitié-Salpêtrière (APHP), Université Paris 6, INSERM, Paris, - - 2014
Optimum duration of dual antiplatelet treatment (DAPT) after coronary stenting remains uncertain, with an unknown efficacy to safety ratio of extended treatment leading to discrepancies between international guidelines and clinical practice. We assessed whether DAPT continuation beyond 1 year after coronary stenting is beneficial. This analysis was a planned extension ...
Pro Michael J MJ Department of Glaucoma, Wills Eye Hospital , Philadelphia, PA , USA - - 2014
ABSTRACT Purpose: The current standard adjunctive agent used in primary trabeculectomy is mitomycin C (MMC), but it is associated with well known complications. The objective of this study is to test the feasibility of the anti-vascular endothelial growth factor (anti-VEGF) agent ranibizumab for adjunctive use instead of MMC (0.4 mg/ml). Materials ...
Fouka Evangelia E Department of Pneumonology, General Hospital G.Papanikolaou, Aristotle University of Thessaloniki, Exohi, 57010, Thessaloniki, Greece, - - 2014
Th17 cells play a crucial role in neutrophilic inflammation and tissue injury in non-cystic fibrosis (non-CF) bronchiectasis. Clarithromycin demonstrates anti-inflammatory and immunomodulatory properties but the effect of long-term clarithromycin prophylaxis on the Th17 response in non-CF bronchiectasis is still unexplored. Th17 response was studied in 22 patients with stable non-CF ...
Taal Walter W Department of Neuro-oncology, Erasmus MC Cancer Institute, Rotterdam, - - 2014
Treatment options for recurrent glioblastoma are scarce, with second-line chemotherapy showing only modest activity against the tumour. Despite the absence of well controlled trials, bevacizumab is widely used in the treatment of recurrent glioblastoma. Nonetheless, whether the high response rates reported after treatment with this drug translate into an overall ...
Traversi Claudio C Department of Medicine, Surgery and Neuroscience, University of Siena, Viale Bracci 1, 53100, Siena, - - 2014
To evaluate the long-term efficacy of bevacizumab in the treatment of choroidal neovascularization (CNV) secondary to pathological myopia. In this retrospective single-center non-comparative study the medical records of 29 eyes from 29 patients with naïve CNV secondary to high myopia and at least 42 months of follow up were reviewed. All ...
Naini Farhad B FB *Department of Orthodontics, Kingston and St George's Hospital and Medical School, - - 2014
Summary BACKGROUND : The nasolabial angle, particularly its lower component, i.e. the upper lip inclination (ULI), is an important keystone in treatment planning. Normative data for this parameter are not available. A quantitative evaluation of the aesthetic impact of ULI on perceived attractiveness and threshold values of desire for treatment ...
Al-Khateeb Susan N SN Department of Preventive Dentistry, Faculty of Dentistry, Jordan University of Science and Technology, Irbid, Jordan - - 2014
Summary OBJECTIVES : The aim of this study was to determine the occlusal bite force (OBF) changes, at the incisal and molar regions, after orthodontic treatment with functional appliance therapy in preadolescent subjects. OBF was measured for patients (17 females and 16 males) before and after the treatment with Andresen ...
Hurford Robert R Stroke and Vascular Research Centre, Institute of Cardiovascular Sciences, University of Manchester, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Manchester, UK Comprehensive Stroke Centre, Greater Manchester Neurosciences Centre, Salford Royal NHS Foundation Trust, Manchester, - - 2014
Orolingual angio-oedema is a recognised complication of tissue plasminogen activator (tPA) for ischaemic stroke. We investigated its incidence, clinical characteristics and relationship with other factors in patients receiving tPA at a UK centre. 530 consecutive patients (median age 70 years) receiving tPA treatment for confirmed ischaemic stroke were included. Cases were ...
Franeková Janka - - 2014
Abstract Background: Galectin-3 is an emerging biomarker of heart failure and of myocardial fibrosis risk. Monitoring of galectin-3 is essential during treatment with galectin-3 inhibitors. The aim of our study was to assess long-term biological variability in a specific group of unhealthy subjects. Methods: The biological variability of galectin-3 was ...
Zhao Jialiang J Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, 1, Shuai Fu Yuan, Dongcheng District, Beijing, 100730, China, - - 2014
To evaluate the efficacy and safety of monthly ranibizumab 0.5 mg in Chinese patients with subfoveal choroidal neovascularization (CNV) secondary to neovascular age-related macular degeneration (nAMD). A 12-month open-label single-arm multicenter phase III study that included treatment-naïve (study eye) patients with primary/recurrent subfoveal CNV secondary to AMD. Patients (N = 114) aged ≥50 years ...
Richardson Monica L ML Stanford University School of Medicine, Stanford, - - 2014
To determine whether conservative or surgical therapy is more cost effective for the initial treatment of stress urinary incontinence. We created a decision tree model to compare costs and cost effectiveness of three strategies for the initial treatment of SUI: a) continence pessary b) pelvic floor muscle therapy c) mid-urethral ...
Murina Filippo F Outpatient Department of Vulvar Disease, V. Buzzi Hospital-ICP-University of Milan, Milan, - - 2014
To compare the efficacy of the short-term application of clobetasol propionate 0.05% (CLB) and mometasone furoate 0.05% (MMF) in the treatment of vulvar lichen sclerosus (VLS). This study was a retrospective review of 96 women who were diagnosed with lichen sclerosus with a follow-up of at least 1 year. Of ...
Yamamoto Erica E Pediatric Gastroenterology Division, Escola Paulista de Medicina, Universidade Federal de São - - 2014
AIM:: to estimate the rate of clinical and endoscopic relapse after initial treatment of erosive peptic esophagitis in children and adolescents. 24 patients (2.1 to 16.4 year-old, mean ± SD: 9.9 ± 3.1; M:F 3) with healed endoscopic erosive esophagitis and without GERD-predisposing conditions were followed up for 4 to 32.9 months (mean 20.8 yrs ± 10.6). ...
Tremaine Anne Marie AM *Department of Dermatology and Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; †Goldman, Butterwick, Fitzpatrick, Groff & Fabi: Cosmetic Laser Dermatology, San Diego, - - 2014
Despite being the gold standard for lower extremity reticular vein treatment, few studies have yet evaluated foam sclerotherapy for hand veins. This retrospective study evaluates the safety and efficacy of foam sclerotherapy for reticular veins of the dorsal hands. A telephone-based questionnaire was used for patient self-assessment of overall improvement, ...
Yun Woo Jin WJ *All the authors are affiliated with the Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, - - 2014
Recently, intense pulsed light (IPL) and low-fluence Q-switched neodymium-doped yttrium aluminum (LF-QS-Nd:YAG) laser have been successfully used to treat melasma. To evaluate the effectiveness and safety of combined novel fractionated IPL (IPL-F) with LF-QS-Nd:YAG laser in patients with melasma. Twelve patients underwent 6 treatment sessions of concomitant IPL-F and LF-QS-Nd:YAG ...
Zhang Yifei Y Rui-jin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, - - 2014
We recently demonstrated a beneficial effect of metformin compared with glipizide in type 2 diabetic patients regarding cardiovascular outcomes for 3-year treatment in the SPREAD-DIMCAD study. However, the potential mechanism for the clinical effects remains unclear. Here, we performed a comprehensive lipidomics study to evaluate the different lipid metabolites in ...
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