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Mora-Soler A - - 2014
Background: the duodenum is the most common location for ectopic varices. Bleeding is rare, but when it appears, it is massive and difficult to control.Material and methods: retrospective description of five clinical cases of digestive bleeding secondary to duodenal varices that we observed between the years 2011 and 2012, together ...
Navas-López V M - - 2014
Objectives: to describe the efficacy and safety of adalimumab (ADA) in inducing clinical remission and reducing inflammation of intestinal mucosa in children with Crohn´s disease (CD).Methods: we carried out a descriptive, observational study with all patients diagnosed with CD and treated with ADA between January 2007 and March 2013. Disease ...
Kragballe K K Department of Dermatology, Århus University Hospital, Århus, - - 2014
The fixed combination calcipotriol plus betamethasone dipropionate gel is a first-line treatment for psoriasis vulgaris. The objective was to perform a large-scale assessment of tolerability of fixed combination gel (Cal/BD). Analysis was performed on pooled 8-week safety data from nine clinical trials evaluating once-daily Cal/BD treatment of scalp (n = 6) and ...
Aksakalli S S Department of Orthodontics, Faculty of Dentistry, Bezmialem Vakif University, Istanbul, - - 2014
Objectives: To successfully meet expectations on facial esthetics, it is important to understand normal craniofacial growth and the impact of orthodontic treatment thereon. To date, there have been few studies documenting changes in facial esthetics through photography. The objective of this study was to compare facial soft tissue esthetics before ...
Baker Christine C Merial Limited, 115 Transtech Drive, Athens, GA, USA. Electronic address: - - 2014
The efficacy of a novel topical combination of fipronil 8.3% (w/v), (S)-methoprene 10% (w/v), eprinomectin 0.4% (w/v) and praziquantel 8.3% (w/v) (BROADLINE(®)) was tested against adult and immature stages of Ctenocephalides felis fleas in six studies. For that purpose, fleas from different colonies from North America, Germany and South Africa ...
Burdick Stacy S Animal Medical Center, Department of Internal Medicine, 510 E 62nd St, New York, NY - - 2014
Objective-To describe the technique and evaluate short- and long-term outcomes in female dogs after endoscopic-guided laser ablation (ELA) of various vestibulovaginal septal remnants (VVSRs). Design-Retrospective case series. Animals-36 dogs. Procedures-Medical records of dogs with VVSRs that underwent ELA were retrospectively reviewed. All patients underwent complete cystourethrovaginoscopy for diagnosis and treatment. ...
Stanworth Simon J SJ NHS Blood and Transplant/Oxford University Hospitals NHS Trust, John Radcliffe Hospital, Oxford, United Kingdom; Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom; NHSBT/MRC Clinical Studies Unit, NHS Blood and Transplant, Cambridge, United - - 2014
A recent randomized trial compared a policy of no prophylaxis with a policy of prophylactic platelet (PLT) transfusions at counts of fewer than 10 × 10(9) /L in patients with hematologic malignancies. The results suggested the effectiveness of prophylactic PLT transfusions may vary according to patient diagnosis and treatment plan. This article ...
Ogawa Eiichi E Department of General Internal Medicine, Kyushu University Hospital, Fukuoka, - - 2014
Thrombocytopenia (TCP) of chronic hepatitis C patients with cirrhosis has a negative impact on the management of interferon-based treatment. The aim of this study is to evaluate the efficacy and safety of telaprevir (TVR)-based triple therapy for patients who have undergone splenectomy (Spx). This prospective, multicenter study consisted of 80 ...
Harsten Andreas A Department of Anaesthesiology, Hässleholm Hospital, 281 25, Hässleholm, - - 2014
Elective knee and hip arthroplasty are common surgical procedures. Improved anaesthetic and nutritional care has the potential of increasing patient satisfaction and reducing length of hospital stay (LOS). The overall aim of this thesis was to evaluate the effect of perioperative nutrition and different anaesthetic techniques on per- and postoperative ...
Dadu Ramona R Departments of Endocrine Neoplasia and Hormonal Disorders and Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Department of Endocrinology, Diabetes and Metabolism, Baylor College of Medicine, Houston, Texas, - - 2014
Sorafenib has proven efficacy in advanced differentiated thyroid cancer (DTC), but many patients must reduce the dose or discontinue treatment because of toxicity. The tolerability and efficacy of lower starting doses of sorafenib for DTC remain largely unstudied.Methods.We retrospectively examined overall survival, time to treatment failure, time to progression, discontinuation ...
Shen Zhou Z Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277, Jiefang Road, Wuhan, 430022, Hubei, - - 2014
To evaluate the efficacy and safety of combined use of percutaneous drainage and urokinase injection to treat patients with large subcapsular renal hematoma. We retrospectively analyzed the data of 20 patients with large subcapsular renal hematoma who were treated with percutaneous drainage and urokinase at our institutes between 2002 and ...
Simon Dominique D Diabetes Department, Pitié-Salpétrière Hospital, and Pierre et Marie Curie University, Paris, - - 2014
There is an increasing interest for real-life data on drug use in many countries. Reimbursement authorities more and more request observational studies to assess the conditions of use of the products but also to improve knowledge about efficacy and safety in the real world and on a longer term than ...
Viana Lucas M LM Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA; Faculty of Health Sciences, University of Brasilia, Brasilia, Distrito Federal, - - 2014
Hypothesis/Objective: Vertigo attacks in most cases of Meniere's disease are successfully treated with lifestyle changes and medication. However, approximately 6% of patients with Meniere's Disease develop drop attacks, a potentially life-threatening condition. Traditional treatment for drop attacks has been surgical labyrinthecctomy. The objective of this study was to assess the ...
Chen Hong-Lei HL *Department of Gastrointestinal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Tianhe District †Department of Gastrointestinal and Colorectal Surgery, the First Affiliated Hospital, Sun Yat-sen University, Yuexiu District, Guangzhou, Guangdong Province, P.R. - - 2014
The aim of this meta-analysis was to compare the outcomes of Ligasure hemorrhoidectomy and stapled hemorrhoidectomy for prolapsed hemorrhoids. Original studies in any language were searched from MEDLINE database, PubMed, Web of science and the Cochrane Library database, and Wangfang database. Randomized control trials that compared Ligasure hemorrhoidectomy with stapled ...
Rush Ryan B - - 2014
To determine the effectiveness and direct medical costs of treat-and-extend (TAE) intravitreal bevacizumab (IVB) for the treatment of branch retinal vein occlusion (BRVO)-associated macular edema (ME). Retrospective chart review of 52 consecutive patients diagnosed with BRVO-associated ME treated with IVB using a TAE protocol. Mean change in logMAR vision was ...
Ehlken C C Eye Center, Albert-Ludwigs-University, Freiburg, - - 2014
BackgroundAlthough anti-VEGF therapy of exudative AMD with bevacizumab and ranibizumab proved efficacious in the majority of patients, CNV activity does not respond to continued treatment after repeated injections in a considerable amount of patients. These are referred to as nonresponders. A change of the drug to bevacizumab or ranibizumab could ...
Ulrich Martina M Dermatologie am Regierungsviertel, Luisenstr. 54/55, 10117 Berlin, - - 2014
Actinic keratosis (AK) is a common skin disease seen in daily practice. It is associated with a risk of progression to invasive squamous cell carcinoma and can be regarded as a marker of increased risk for non-melanoma skin cancer. The use of a field-directed treatment approach reflects the need to ...
Agard C C Department of Internal Medicine, Hôtel-Dieu University Hospital , Nantes , - - 2014
Objectives: Ischaemic digital ulcers (DUs) are a common complication of systemic sclerosis (SSc). This study aimed to characterize patients with SSc and ongoing DUs treated with the endothelin receptor antagonist bosentan in clinical practice in France. Method: An observational, retrospective, longitudinal study was conducted in 10 French expert centres. Medical ...
Spreen Marlon M Department of Radiology, HagaZiekenhuis, PO box 40551, 2504 LN, The Hague, The Netherlands, - - 2014
In many patients with critical limb ischemia (CLI), transfemoral endovascular recanalization is the preferred treatment. Transpopliteal treatment may be used in patients with inaccessible groins. This retrospective study regards transpopliteal stenting of superficial femoral artery (SFA) occlusions using a 4F system. Eleven patients (4 male and 7 female [mean age ...
Gonda David D DD Division of Neurosurgery - - 2014
Object Using a database that enabled longitudinal follow-up, the authors assessed the long-term outcomes of unruptured cerebral aneurysms repaired by clipping or coiling. Methods An observational analysis of the California Office of Statewide Health Planning and Development (OSHPD) database, which follows patients longitudinally in time and through multiple hospitalizations, was ...
Poordad Fred F From the Texas Liver Institute-University of Texas Health Science Center, San Antonio (F.P.); Henri Mondor Hospital, Assistance Publique-Hôpitaux de Paris, University Paris-Est, INSERM Unité 955, Créteil, France (C.H.); AbbVie, North Chicago, IL (R.T., S.S.L., B.D.S.-T., C.A.C., A.L.C., T.P., B.B.); Digestive Disease Institute, Virginia Mason Medical Center, Seattle (K.V.K.); Johann Wolfgang Goethe University, Frankfurt (S.Z.), Medizinische Hochschule Hannover, Hannover (H.W.), and Universitätsklinikum Leipzig, Leipzig (T.B.) - all in Germany; Institute of Liver Studies, King's College Hospital, London (K.A.); Liver Institute of Virginia, Newport News (M.L.S.); University of British Columbia, Vancouver, Canada (E.M.Y.); and Liver Unit, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Barcelona - - 2014
Background Interferon-containing regimens for the treatment of hepatitis C virus (HCV) infection are associated with increased toxic effects in patients who also have cirrhosis. We evaluated the interferon-free combination of the protease inhibitor ABT-450 with ritonavir (ABT-450/r), the NS5A inhibitor ombitasvir (ABT-267), the nonnucleoside polymerase inhibitor dasabuvir (ABT-333), and ribavirin ...
Freeman Richard K RK Department of Thoracic and Cardiovascular Surgery, St. Vincent Hospital, Indianapolis, Indiana. Electronic address: - - 2014
Patients with severe heart failure often have recurrent pleural effusions that produce dyspnea and shortness of breath. It is unclear whether chemical pleurodesis or the placement of a tunneled pleural catheter that can be used for intermittent pleural drainage produces superior palliation, a shorter hospital stay, and less morbidity. This ...
Heller Robert S RS Cerebrovascular and Endovascular Division, Department of Neurosurgery; - - 2014
Object The benefits of treating intracranial aneurysms in the region of the anterior visual pathways are well understood. However, the adverse effects of endovascular stenting across the ophthalmic artery have received little attention. The authors reviewed their experience with patients who had stents deployed across the ophthalmic artery origin. Methods ...
Hattangadi-Gluth Jona A JA Department of Radiation Medicine and Applied Sciences, University of California San Diego, San Diego, - - 2014
To evaluate the obliteration rate and potential adverse effects of single-fraction proton beam stereotactic radiosurgery (PSRS) in patients with cerebral arteriovenous malformations (AVMs). From 1991 to 2010, 248 consecutive patients with 254 cerebral AVMs received single-fraction PSRS at our institution. The median AVM nidus volume was 3.5 cc (range, 0.1-28.1 cc), 23% ...
Lee Sang Ju SJ Yonsei Star Skin & Laser Clinic, Seoul, - - 2014
Hypertrophic burn scars induce cosmetic and functional complications. Although there are various treatment modalities, an ideal method has not yet been found. Recently, numerous laser treatment modalities have been introduced with encouraging results. To assess the efficacy and safety of combination therapy with laser-cision and pinhole method using a carbon ...
Choi Kyoung Sub KS 1 Graduate School of Yonsei University , Seoul, South Korea - - 2014
Abstract Purpose: To demonstrate that ultraviolet-A (UV-A) and voriconazole combination therapy is more effective than voriconazole single treatment for fungal keratitis. Methods: The in vitro UV-A (375 nm) fungicidal effect was evaluated on Fusarium solani solutions. Each fungal solution was irradiated with different UV-A irradiation doses. Also, a fungal solution containing ...
Mohammadi Ekram E Department of Physiology, Faculty of Biological Sciences, Shaheid Beheshti University , G.C., Tehran , - - 2014
Abstract Background: The purpose of this study was to determine if normobaric hyperoxia (HO) pre-conditioning offers durable neuroprotection against cerebral ischaemia and its effects on NCX1 expression. Methods: Rats were divided into two experimental groups. The first group was exposed to 95% inspired HO for 4 hours/day for 6 consecutive ...
Anakwenze Oke A OA Department of Orthopaedic Surgery, Kaiser Permanente, San Diego, California, U.S.A.. Electronic address: - - 2014
The purpose of this systematic review was to critically examine the outcomes of lateral ulnar collateral ligament reconstruction for posterolateral rotatory instability (PLRI) of the elbow. A systematic review of the literature was performed. Two reviewers assessed and confirmed the methodologic and patient data from the included studies. Frequency-weighted means ...
Woźniak Magdalena Maria MM Department of Pediatric Radiology, Medical University of Lublin, Al. Racławickie 1, 20-059, Lublin, Poland, - - 2014
There are many controversies surrounding the effectiveness of endoscopic treatment of vesicouretheral reflux (VUR) in children, thus it is of highest priority to analyze factors influencing the outcome of therapy and to search for new methods that would increase the success rate and reduce the number of reinjections. The aim ...
Salhofer-Polanyi S S Department of Neurology, Medical University of Vienna, Vienna, - - 2014
To minimize the risk of progressive multifocal leucoencephalopathy (PML), treatment with natalizumab is often stopped after 2 years, but evidence upon rebound of disease activity is limited and controversial. To evaluate effects of natalizumab discontinuation on clinical disease activity within twelve months after cessation. We retrospectively analyzed data of 201 patients ...
Nazir J J Astellas Pharma Europe Ltd, Chertsey, Surrey, - - 2014
Abstract Objective: To carry out a cost-utility analysis comparing initial treatment of patients with overactive bladder (OAB) with solifenacin 5 mg/day versus either trospium 20 mg twice a day or trospium 60 mg/day from the perspective of the German National Health Service. Methods: A decision analytic model with a three ...
Feld Jordan J JJ From the Toronto Centre for Liver Disease, University of Toronto, Toronto (J.J.F.); Digestive Disease Institute, Virginia Mason Medical Center, Seattle (K.V.K.); AbbVie, North Chicago, IL (E.C., J.X., T.P.-M., B.D.-T., L.L., T.P., B.B.); New York University School of Medicine, New York (S.S.); University of Florida College of Medicine, Gainesville (D.R.N.); Gallipoli Medical Research Foundation and School of Medicine, University of Queensland, Brisbane, Australia (D.C.); Karolinska University Hospital Huddinge, Karolinska Institutet, Stockholm (O.W.); and Louisiana Research Center, Shreveport - - 2014
Background The interferon-free combination of the protease inhibitor ABT-450 with ritonavir (ABT-450/r) and the NS5A inhibitor ombitasvir (also known as ABT-267) plus the nonnucleoside polymerase inhibitor dasabuvir (also known as ABT-333) and ribavirin has shown efficacy against the hepatitis C virus (HCV) in patients with HCV genotype 1 infection. In ...
Kowdley Kris V KV From the Digestive Disease Institute, Virginia Mason Medical Center, Seattle (K.V.K.); Henry Ford Health Systems, Detroit (S.C.G.); University of Pennsylvania, Philadelphia (K.R.R.); University of California Davis Medical Center, Sacramento (L.R.), University of California at San Diego Medical Center, San Diego (M.C.), Scripps Clinic, La Jolla (P.J.P.), and Gilead Sciences, Foster City (G.M.S., D.A., E.S., R.H.H., P.S.P., W.T.S., J.G.M.) - all in California; Hofstra North Shore-Long Island Jewish School of Medicine, Manhasset, NY (D.E.B.); Texas Liver Institute and University of Texas Health Science Center, San Antonio (E.L.), and Texas Clinical Research Institute, Arlington (R.G.) - both in Texas; Liver Institute of Virginia, Bon Secours Health System, Richmond and Newport News (M.L.S.), Digestive and Liver Disease Specialists, Norfolk (M.R.), and Metropolitan Liver Diseases, Fairfax (V.R.) - all in Virginia; Center for Liver Diseases, School of Medicine, University of Miami, Miami (E.S.); Quality Medical Research, Nashville (R.H.); Saint Louis University, St. Louis (A.M.D.); Duke University Medical Center, Durham (A.J.M.), and University of North Carolina, Chapel Hill (M.W.F.) - both in North Carolina; and Indianapolis Gastroenterology Research Foundation, Indianapolis - - 2014
Background High rates of sustained virologic response were observed among patients with hepatitis C virus (HCV) infection who received 12 weeks of treatment with the nucleotide polymerase inhibitor sofosbuvir combined with the NS5A inhibitor ledipasvir. This study examined 8 weeks of treatment with this regimen. Methods In this phase 3, ...
Barteselli Giulio G Department of Ophthalmology, Jacobs Retina Center at Shiley Eye Center, University of California San Diego, La Jolla, CA, - - 2014
To evaluate the efficacy of a standardised combination therapy for clinically significant diabetic macular oedema using bevacizumab injections followed by navigated laser photocoagulation to stabilise retinal thickness. In this pilot study we retrospectively reviewed charts and imaging of 23 eyes treated with the standardised combination regimen. Eyes initially received monthly ...
Jia Renbing R Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of - - 2014
IMPORTANCE Low-flow orbital or periorbital venous malformation (OVM) is the most common periorbital vascular lesion that may produce an appearance defect, visual dysfunction, internal hemorrhage, and thrombosis. Intralesional injection of pingyangmycin as a minimally invasive, gentle intervention may have better outcomes in treating low-flow OVMs compared with other currently used ...
Kim Benjamin J BJ Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, 51 N 39(th) St, Philadelphia, PA, 19104. Electronic address: - - 2014
To evaluate transient, large visual acuity (VA) decreases, termed sporadic vision loss, during anti-vascular endothelial growth factor treatment for neovascular age-related macular degeneration (AMD). Cohort within a randomized clinical trial. Setting: Comparison of AMD Treatments Trials (CATT). Study Population: 1185 CATT patients. Main Outcome Measures: incidence of sporadic vision loss ...
Mantel Irmela I Department of Ophthalmology, University of Lausanne, Jules Gonin Eye Hospital, Lausanne, - - 2014
The purpose of this study was to clinically validate an individually planned treatment regimen for neovascular age-related macular degeneration (nAMD), termed, observe and plan. This regimen was based on the predictability of an individual's need for retreatment and aimed to reduce the clinical burden, while obtaining good functional results. This ...
Hernández-Durán Silvia S Neurosurgical Service, Harvard Medical School, Massachusetts General Hospital, 55 Fruit Street, Wang 745, Boston, MA, USA, - - 2014
The purpose of this study was to present a meta-analysis on the safety and efficacy of different endovascular modalities when treating vertebral artery dissections, since ideal treatment remains controversial. We performed a meta-analysis of 39 retrospective studies involving different treatment modalities for vertebral artery dissections in adults and obtained weighted ...
Farr Jack J OrthoIndy, Indianapolis, Indiana, - - 2014
BACKGROUND:Biological repair of cartilage lesions remains a significant clinical challenge because of the lack of natural regeneration and limited treatment options. HYPOTHESIS:Treatment of articular cartilage lesions in the knee with particulated juvenile articular cartilage (PJAC) will result in an improvement in patient symptoms of pain and function and magnetic resonance ...
Luk Lauren L Oregon Sinus Center, Department of Otolaryngology-Head and Neck Surgery, Oregon Health and Science University, Portland, - - 2014
Potassium-titanyl-phosphate (KTP) laser photocoagulation is commonly used for treatment of hereditary hemorrhagic telangiectasia-related epistaxis (HHT-RE). Electrosurgical plasma coagulation (EPC), also known as coblation, has not been rigorously evaluated for HHT-RE. Patients seeking treatment for HHT-RE between September 2010 and September 2012 were prospectively randomized (1:1) to KTP or EPC in ...
Durmus Basak B Department of Pediatric Dentistry, Faculty of Dentistry, Marmara University , Istanbul, Turkey - - 2014
Abstract Objective: The purpose of this study was to assess whether the diode laser (DL) pulpotomy method is a suitable alternative to formocresol (FC) and ferric sulphate (FS) pulpotomies in human primary teeth. Background data: Pulpotomy is the amputation of infected coronal pulp to maintain radicular pulp vitality and function. ...
Awad Samir S SS Baylor College of Medicine, Section of Surgical Critical Care, Houston, - - 2014
Background. Ceftobiprole, the active moiety of ceftobiprole medocaril, is a novel broad-spectrum cephalosporin, with bactericidal activity against a wide range of Gram-positive bacteria, including Staphylococcus aureus (including methicillin-resistant strains) and penicillin- and ceftriaxone-resistant pneumococci, and Gram-negative bacteria, including Enterobacteriaceae and Pseudomonas aeruginosa. Methods. A double-blind, randomized, multicenter study of 781 patients with ...
Hayashi Norio N Kansai Rosai Hospital, Hyogo, - - 2014
In a Japanese Phase II study, the hepatitis C virus NS3/4A protease inhibitor simeprevir demonstrated potent antiviral activity and significantly improved sustained virologic response rates when added to peginterferon α-2a/ribavirin in treatment-naïve patients infected with hepatitis C virus genotype 1. CONCERTO-1 was a Phase III, randomized, double-blind, placebo-controlled trial. Treatment-naïve ...
Andujar-Plata P P Endocrinology Division, Complejo Hospitalario Universitario de Santiago de Compostela, Universidad de Santiago de Compostela, Travesía da Choupana s/n, 15706, Santiago de Compostela, La Coruña, - - 2014
The treatment of adults with GH deficiency (GHD) with human recombinant growth hormone has interindividual variability and several factors influence it. The aims of this study were : 1-to analyze the GH receptor (GHR) genotype in terms of exon 3 deletion GHR (d3-GHR) in adults with GHD; 2-to assess the ...
Schüttler Karl F KF Department of Orthopedics and Rheumatology, University Hospital Marburg, Baldingerstrasse, 35043, Marburg, - - 2014
Meniscal injury resulting in segmental loss of meniscal tissue is a major risk factor for the development of osteoarthritis. Tissue engineering strategies have provided scaffolds for meniscal regeneration in order to establish a treatment option for patients with limited opportunities for meniscal reconstruction. The purpose of this study was to ...
Gögenur Ismail I Department of Surgery, University of Copenhagen, Herlev Hospital, - - 2014
The aim was to examine the effect of perioperative melatonin treatment on clinical cardiac morbidity and markers of myocardial ischemia in patients undergoing elective surgery for abdominal aortic aneurism. Reperfusion injury results in increased cardiac morbidity in patients undergoing surgery for abdominal aortic aneurisms (AAA). A randomized, placebo controlled, clinical ...
Saris Daniel D University Medical Center Utrecht, Utrecht, the - - 2014
BACKGROUND:Randomized controlled trials studying the efficacy and safety of matrix-applied characterized autologous cultured chondrocytes (MACI) versus microfracture (MFX) for treating cartilage defects are limited. PURPOSE:To compare the clinical efficacy and safety of MACI versus MFX in the treatment of patients with symptomatic cartilage defects of the knee. STUDY DESIGN:Randomized controlled ...
Boons Christel Clm - - 2014
The antitumor drug nilotinib has a large inter- and intra individual variability in pharmacokinetics. Adherence to treatment may substantially influence plasma levels and has been recognized as the most important determinant of treatment failure in chronic myeloid leukemia (CML). A better understanding of the various factors contributing to the efficacy ...
Brinjikji Waleed W Department of Radiology, Mayo Clinic, Rochester, Minnesota, - - 2014
Expansion of the endovascular and surgical workforce in the USA might lead to carotid revascularization procedures being carried out at low volume centers. To evaluate trends in the treatment of carotid stenosis at high volume centers in the USA and compare outcomes by hospital volume. Using the Nationwide Inpatient Sample, ...
O'Neill Kevin R KR Washington University, Department of Orthopaedics, St. Louis, Missouri, - - 2014
Study Design. Retrospective review of prospective database.Objective. To investigate the long-term results following extension of previous long spine fusions to the sacrum.Summary of Background Data. Long spine fusions not involving the sacrum may be complicated by distal degeneration and require subsequent extension to the sacrum. The clinical and radiographic outcomes ...
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