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Results 401 - 450 of 9702
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Levin Adriane A - - 2014
Although biologic therapies have been shown to be more effective than traditional systemic therapies in clinical trials for the treatment of psoriasis, the drug survival time and reasons for discontinuation of biologics in clinical practice have not been compared with those of conventional systemic therapies.<BR /> Retrospective, cross-sectional.<BR /> All ...
Kohorst John J - - 2014
Treatment of hidradenitis suppurativa has been studied, but treatment strategies and outcomes have not been reported for a large community-based group of patients.<BR /> We sought to determine the treatments most commonly prescribed and the performance of all systemic and surgical treatments used in hidradenitis suppurativa patients in Olmsted County, ...
Swelem Amal Ali - - 2014
Purpose: This study investigated changes in oral health-related quality of life (OHRQoL) in partially edentulous patients treated with removable dental prostheses (RDPs), fixed dental prostheses (FDPs), fixed-removable (combined) restorations (COMBs), and implant-supported fixed prostheses (ISFPs). Materials and Methods: A total of 200 patients (30 to 50 years old) were enrolled: ...
Xia Lei L From the *Department of Neurosurgery, XinHua Hospital (The Cranial Nerve Disease Center of Shanghai), Shanghai JiaoTong University School of Medicine, Shanghai, China; and †Institute of Neurosurgery, Catholic University of Rome, Rome, - - 2014
Microvascular decompression has been now accepted worldwide as a reasonable treatment for trigeminal neuralgia, yet, as a functional operation in the cerebellopontine angle, this process may be risky and the postoperative outcomes might not be good enough sometimes. To assess the effectiveness and safety of microvascular decompression for treatment of ...
Kuismanen Kirsi K Department of Obstetrics and Gynaecology and School of Medicine and - - 2014
The purpose of our study was to find out whether transurethral injections of autologous adipose stem cells (ASCs) are an effective and a safe treatment for female stress urinary incontinence (SUI). We treated five SUI patients with ASCs combined with bovine collagen gel and saline. Prior to the treatment, the ...
O'Callaghan Adrian A Department of Vascular and Endovascular Surgery, Cleveland Clinic Foundation, Cleveland, - - 2014
Endovascular options for the treatment of proximal thoracic and arch disease have evolved over the years. In this manuscript, we review the midterm results of fenestrated compared with chimney configurations for proximal aortic aneurysm disease. We performed an analysis of all patients with chimney grafts or custom fenestrated endografts used for ...
Munang Melinda M Birmingham Heartlands Hospital, Department of Infection and Tropical Medicine - - 2014
Background: There have been few studies on risk factors and treatment outcomes of isoniazid (H)-resistant tuberculosis (TB) and optimal treatment regimens are debated. Aim: To identify risk factors for H-resistant TB, describe treatment regimens and compare these to national guidelines and describe short-term outcomes of H-resistant TB in Birmingham, United ...
Yi Yong Jin YJ Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of - - 2014
Evening administration of the conventional immediate-release (IR) formulation of simvastatin is recommended because of its short half-life (1.9 hours). In a healthy population, morning administration of a controlled-release (CR) formulation of simvastatin was shown to have equivalent lipid-lowering efficacy and a safety profile similar to that of evening doses of ...
Kissin Eugene Y EY Division of Rheumatology, Boston University School of Medicine, Boston, Massachusetts. Electronic address: - - 2014
The European League Against Rheumatism (EULAR) recently updated its recommendations on the management of rheumatoid arthritis (RA) with synthetic and disease-modifying antirheumatic drugs (DMARDs), motivated by the availability of new treatment options over the past 3 or 4 years. Modifications since 2010 include the removal of the recommendation of the ...
Yarboro Douglas D DD The Wound Care Center of Northern Hospital of Surry County, Mount Airy, NC; email: dougyarboro@ - - 2014
Transcutaneous electrical nerve stimulation (TENS) is used to alleviate muscle pain, and there is some evidence it may affect healing in chronic wounds. An 80-year-old male patient with a chronic left lower extremity wound and a history of peripheral arterial disease, type 2 diabetes, hypertension, chronic obstructive pulmonary disease, and ...
Sanatkhani Majid M Oral and Maxillofacial Diseases Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, - - 2014
Oral Lichen Planus (OLP) is a chronic mucocutaneous disease with an immunological etiology. This study was conducted to evaluate the effect of cedar honey in the treatment of erosive- atrophic OLP. Thirty patients with a confirmed clinical and histopathologic diagnosis of OLP participated in this randomized clinical trial in Mashhad ...
Selid Paul D - - 2014
To compare treatment of exudative age-related macular degeneration (AMD) with bevacizumab versus aflibercept in terms of central retinal thickness (CRT) and best corrected visual acuity (BCVA). A retrospective cohort study examining changes in CRT and BCVA over 12 months of follow-up in 111 patients treated with bevacizumab and 91 treated ...
Nambiar Arjun A Department of Urology, Morriston Hospital, Swansea, United - - 2014
This chapter focuses on the position of botulinum toxin type A in the treatment pathway for overactive bladder (OAB) and neurogenic lower urinary tract dysfunction associated with neurogenic detrusor overactivity (NDO), and the recommendations of the major international guideline groups. Recommendations of different guideline groups may vary, especially when evidence ...
Ebnezar John J Ebnezar Orthopedic Center, Bengaluru, Karnataka, - - 2014
OA Knee is the most common arthritis. Knee replacement Surgeries are being done increasingly in the present times. This has led to the violation of the standard indications and when knees are replaced ignoring other co - musculoskeletal conditions it results in the surgery failing early. This is about a ...
Anchala Praveen R - - 2014
Spinal metastatic lesions are a common occurrence among oncology patients and contribute to significant morbidity. Treatment options have been limited in their effectiveness and scope to this point. This study aims to report the safety and efficacy of radiofrequency ablation (RFA) of malignant spinal lesions using a novel RFA bipolar ...
Park Sang Woo SW Department of Radiology, Konkuk University Hospital, Konkuk University School of Medicine, Seoul 143-729, - - 2014
To compare the efficacy and adverse effects of endovenous foam sclerotherapy (EFS) and liquid sclerotherapy (ELS) using a microcatheter for the treatment of varicose tributaries. From December 2007 to January 2009, patients with venous reflux in the saphenous vein were enrolled. The foam or liquid sclerosant was injected through a ...
Noaiseh Ghaith G Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. - - 2014
There are currently no head-to-head comparisons of sialagogues for Primary Sjögren's syndrome (pSS). We compared the tolerability and side effect profile of pilocarpine and cevimeline in patients with pSS and determined clinical, laboratory and pathological variables associated with therapeutic failure. We retrospectively reviewed the use of pilocarpine and cevimeline in ...
Vidal G G Neurology, Radiology and Neurosurgery, Ochsner Clinic Foundation, New Orleans, LA, - - 2014
Most patients with large vessel occlusion (LVO) present with high NIHSS, and it has been shown that initial NIHSS is a predictor of outcomes in patient with acute ischemic stroke. The usefulness of neuroendovascular reperfusion has been a controversial topic. The aim of this study was to compare the outcomes ...
Chalouhi N N Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, PA, - - 2014
Stenting techniques such as stent-assisted coiling and flow diversion are increasingly used for treatment of intracranial aneurysms. In previous reports, patients were pretreated were aspirin and clopidogrel prior to the intervention for prevention of thromboembolic complications. Prior studies also often rely on aspirin response and P2Y assessment, which often delays ...
Park M M Neurological Surgery, Barrow Neurological Institute, Phoenix, AZ, - - 2014
The Pipeline Embolization Device (PED, eV3 Neurovascular, Irvine, California) has increased the ability of the neurointerventionalist to treat progressively more difficult cerebrovascular pathology. We sought to determine the efficacy of the PED in the treatment of the most recalcitrant of aneurysms, those aneurysms recurring after previous treatments. We retrospectively queried ...
Turk A A 3rd NeuroEndovascular Surgery, Medical University of South Carolina, Charleston, SC, - - 2014
The use of mechanical thrombectomy for treatment of acute ischemic stroke has significantly advanced over the last 5 years. Little data is available analysing the cost relative to the clinical and angiographic outcomes. The aim of this study is to analyze the cost and efficacy of current stroke therapy. A ...
Pierot L L Radiology, Hôpital Maison-Blanche, Reims, - - 2014
To evaluate the feasibility, safety, and efficacy of endovascular treatment with flow diverters (FD) in patients with recanalised and multitreated aneurysms, in a retrospective, multicenter, single-arm study. The study included 29 patients with 29 recanalised aneurysms who were treated by FDs (Silk or Pipeline device). Per and post procedural complications ...
Alexander M M Radiology, Santa Clara Valley Medical Center, San Jose, CA, - - 2014
Endovascular treatment of intracranial atherosclerotic disease is controversial, and optimal treatment remains unclear. Acute ischemic stroke (AIS) due to thrombosis of an in situ stenosis has undergone little investigation. Infarction from such disease in the posterior circulation causes pronounced morbidity. We reviewed outcomes of patients undergoing endovascular treatment of AIS ...
Robert T T Interventional Neuroradiology, Rothschild Foundation Hospital, Paris, - - 2014
Arteriovenous malformations (AVM) of the corpus callosum were rare lesions, accounting for 9-11% of brain AVMs. Microsurgical resection of such lesions remained difficult regarding deep location and possible neuropsychological disasters of extended callosal resection. The introduction of endovascular and radiation therapies fundamentally changed the outcome of these lesions. Since 1995, ...
Alexander M M Radiology, University of Washington, Seattle, CA, - - 2014
Intracranial atherosclerotic disease (ICAD) is often stratified by degree of stenosis. Additional features such as patient demographics and symptom characteristics also affect lesion behavior and response to treatment. This study compares stratification by degree of narrowing to these additional features. Retrospective analysis was performed on patients at 4 hospitals with ...
Chowdhary A A Director of Neurosurgery and Neuro-Interventional Surgery, Overlake Hospital, Bellevue, WA, - - 2014
Radiation exposure during an angiographic procedure may present a significant health risk to patients. The goal of this multicenter case study (CARE) is to compare such exposure in patients treated with the novel Penumbra Coil 400™ System (PC 400) vs. conventional coils. The PC 400 coils are a new generation ...
Walker Paul C - - 2014
This study was designed to evaluate the long-term results using the technique of canal wall reconstruction (CWR) tympanomastoidectomy with mastoid obliteration in the treatment of chronic otitis media with cholesteatoma. Institutional review board-approved retrospective case review. Tertiary referral center. Retrospective review was performed on consecutive patients undergoing CWR tympanomastoidectomy with ...
Cunningham Daniel J - - 2014
Background : We hypothesized that needling of a pedal wart creates local inflammation and a subsequent cell-mediated immune response (CMIR) against human papillomavirus. The primary objective of this study was to investigate whether needling to induce a CMIR against human papillomavirus is an effective treatment for pedal warts compared with ...
Fernández Maria Luz González - - 2014
Background : We sought to assess the biomechanical characteristics of the feet of patients with Charcot neuro-osteoarthropathy and to determine reulceration rates before and after personalized conservative orthotic treatment. Methods : A longitudinal prospective study was performed in 35 patients with Charcot's foot. Although some patients had a history of ...
Lee Min Seok MS Sophie-Marceau Women's Clinic, Daegu, South - - 2014
Vaginal relaxation syndrome (VRS) is both a physical and psychological problem for women and often their partners. Recently the 2940 nm Er:YAG laser has attracted attention for VRS treatment. The current study evaluated the clinical efficacy of this nonsurgical laser procedure. Thirty postpartum females with VRS or vaginal atrophy, ages ...
Min Jang Hwan JH Department of Plastic and Reconstructive Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, - - 2014
For patients with full thickness skin defects, autologous Split-thickness skin grafts (STSG) are generally regarded as the mainstay of treatment. However, skin grafts have some limitations, including undesirable outcomes resulting from scars, poor elasticity, and limitations in joint movement due to contractures. In this study, we present outcomes of Matriderm ...
Joyce Kenneth Michael KM Department of Plastic and Reconstructive Surgery, Galway University Hospital, Galway, - - 2014
Proximal interphalangeal joint (PIPJ) dislocations represent a significant proportion of hand clinic visits and typically require frequent follow-ups for clinical assessment, orthotic adjustments, and physiotherapy. There are a large number of treatment options available for PIPJ dislocations, yet no prospective or controlled studies have been carried out, largely due to ...
Thielecke Marlene M Institute of Microbiology and Hygiene, Campus Benjamin Franklin, Charité University Medicine, Berlin, - - 2014
Tungiasis (sand flea disease) is a neglected tropical disease, prevalent in resource-poor communities in South America and sub-Saharan Africa. It is caused by an inflammatory response against penetrated female sand fleas (Tunga penetrans) embedded in the skin of the host. Although associated with debilitating acute and chronic morbidity, there is ...
Admani Shehla S Division of Pediatric and Adolescent Dermatology, Rady Children's Hospital-San Diego and University of California at San Diego School of Medicine, San Diego, - - 2014
Infantile hemangiomas are benign vascular tumors seen in 4.5 percent of neonates and infants. While most infantile hemangiomas can be managed with active nonintervention, a subset of patients will require more aggressive management. Here the authors review the use of beta-blockers in the treatment of infantile hemangiomas, including oral, topical, ...
Kumar A Jana AJ Department of Periodontology, Narayana Dental College and Hospital, Nellore, Andhra Pradesh, - - 2014
The evaluation of clinical and specific microbiological changes associated with chlorhexidine chip in the chronic periodontitis patients. A total of 30 chronic periodontitis patients (aged 20-65 years) having pocket depth of ≥5 mm in molar teeth were selected and randomly divided into following treatment groups: Group 1 - Scaling and ...
Singh Ajit A Department of Orthopaedics, Rohilkhand Medical College, Bareilly, Uttar Pradesh, - - 2014
The objective of this prospective study was assessment of efficacy of bone marrow aspirate (BMA) (containing plasma rich in growth factors and mesenchymal stem cells) injection in treatment of tennis elbow. A total of 30 adult patients of previously untreated tennis elbow were administered single injection of BMA. This concentrate ...
Tosun Ayse Kavasoglu AK Dr. Ayse Kavasoglu Tosun, Gynecology and Obstetrics, Department Istanbul Medeniyet University, Goztepe Education and Research Hospital, Istanbul, - - 2014
To compare the effectiveness and acceptability of LNG-IUD with oral progesterone (norethisterone acetate; NETA) in achieving a reduction in volume of the myomas, hemoglobin levels, satisfaction of the women. This study includes randomized 30 women treated by LNG-IUD and randomized 30 women treated by oral norethisterone (NETA). All these participants ...
Chen Bing B Bing Chen, Department of Obstetrics and Gynaecology, Air Force General Hospital, PLA, Beijing 100142, - - 2014
To compare outcomes of vaginal and abdominal hysterectomy procedures in women with benign gynaecological diseases. This was a prospective study of outcomes of consecutive patients who underwent total vaginal hysterectomy (VH) or abdominal hysterectomy (AH) for benign gynaecological diseases. Patient characteristics before, during, and after the operations were reviewed. Patients ...
Wu Jian Hui JH Jian Hui Wu, Department of Urology, Second Hospital of Tianjin Medical University, Tianjin Institute of Urology, No. 23 Pingjiang Road, Tianjin 300211, - - 2014
Bladder stones in elderly men are commonly associated with bladder outlet obstruction, and many different treatment modalities have been presented for both these conditions. To evaluate the effectiveness and safety of a novel method concerning spontaneous usage of both monopoplar transurethral resection of the prostate and Holmium Laser cystolithotripsy, we compared ...
Tawfik Abeer Attia AA Dermatology Unit, Department of Medical Applications of Lasers, National Institute of Laser Enhanced Sciences, Cairo University, Giza, - - 2014
Pulsed dye laser has been used successfully in the treatment of nail psoriasis. Intense pulsed light (IPL) has been used in the treatment of plaque psoriasis using a 550-nm filter. To study the efficacy of IPL in the treatment of nail psoriasis. Twenty patients with finger and toe nail psoriasis ...
Tanaka Yohei Y *Clinica Tanaka Plastic, Reconstructive Surgery and Anti-aging Center, Matsumoto, Nagano, Japan; †Department of Dermatology, Tokyo Women's Medical University, Tokyo, Japan; ‡Department of Applied Life Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata, - - 2014
A new multisource phase-controlled radiofrequency (MPCRF) device is widely used for skin tightening and rejuvenation in Asia. To evaluate the efficacy of MPCRF objectively and histologically. An MPCRF device with real-time impedance control was evaluated. Ten Japanese patients were treated one side of the face, and the untreated side served ...
M Isa Ahmed A Assisted Conception Unit, Department of Obstetrics and Gynecology, College of Medicine, King Saud University, Riyadh, Saudi - - 2014
Intrauterine Insemination (IUI) remains the first thought of infertility treatment. To compare the stimulation effects and Pregnancy rate (PR) outcomes of two ovulation induction (OI) medications, human-derived menopausal gonadotrophins (hMGH), Merional (MER), and recombinant follicular stimulating hormone (rFSH), Puregon (PUR), in a cohort of Saudi infertile patients, for better predictability ...
Seo Yu-Jin YJ Department of Orthodontics, School of Dentistry, Kyunghee University, Seoul, - - 2014
The purpose of the current report is to present 6-year long-term stability and 10-year follow-up data for an adult patient who was treated with a tongue elevator for relapsed anterior open-bite. The 19-year-old male patient presented with the chief complaint of difficulty in chewing his food. Collectively, clinical and radiographic ...
Aydogdu Ozgu O Izmir University School of Medicine, Department of Urology, Izmir, - - 2014
We compare BIVAP saline vaporization of the prostate with bipolar transurethral resection of the prostate (TURP) in the treatment of benign prostatic hyperplasia. In total, we included 86 patients treated with BIVAP (n = 44) and bipolar TURP (n = 42). The inclusion criteria were maximum urinary flow rate (Qmax) ...
Jowkar Farideh F Department of Dermatology, Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. - - 2014
Hand eczema is a common distressing skin problem. It is an immune reaction to haptens. Thus, substances that inhibit Immune system can be effective in the treatment of hand eczema. In this study, topical fumaric acid 5% cream is compared with topical steroid in the treatment of hand eczema. Patients ...
Deshmukh Radha A RA Department of Oral Medicine and Radiology, Karnataka Lingayat Education Society's, Vishwanath Katti Institute of Dental Sciences, Karnatak Lingayat Education University, Belgaum, Karnataka, - - 2014
Recurrent aphthous stomatitis (RAS) is an unfortunately most common disease occurring in oral cavity. Although the lesion is usually self-limited, its painful presentation, high frequency of occurrence, and multifactorial etiology leads to significant morbidity. So, an efficient therapeutic strategy is needed to provide relief to the patients. To assess and ...
El-Eweedy Sayed M SM Department of Urology, Faculty of Medicine, Al-Azhar University, Cairo, - - 2014
The aim is to evaluate the long-term safety and efficacy of transobturator tape (TOT) procedure in the treatment of women with stress urinary incontinence (SUI) by subjective and objective measures. A total 48 women with SUI underwent the TOT procedure during the period from December 2005 to February 2008. The ...
Patil Santosh S Reader, Dept of Oral Medicine and Radiology, Chattisgarh Dental College Research Institute, Rajnandgaon, Chattisgarh. - - 2014
Oral submucous fibrosis (OSMF) is a potentially malignant disorder predominantly seen in the Indian subcontinent due to areca nut, tobacco and their products. The aim of the present study was to compare the efficacy of oxitard and aloe vera in the management of OSMF. 120 subjects with OSMF were included ...
van den Bos R R RR Department of Dermatology, Erasmus MC University Medical Centre, - - 2014
The aim was to compare endovenous laser ablation (EVLA) and endovenous steam ablation (EVSA) for great saphenous varicose veins in a non-inferiority study. Patients with primary great saphenous vein reflux were randomized to EVLA (940 nm) or EVSA (SVS™). Primary outcomes were treatment success (vein obliteration) at 52 weeks, and Venous Clinical ...
Sunseri Whitney W 1Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania; 2Department of Pediatrics, Connecticut Children's Medical Center, Hartford, Connecticut; 3Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada; 4Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, ON, Canada; 5Department of Pediatrics, I.W.K. Health Center, Halifax, NS, Canada; 6Pediatric Gastroenterology, Goryeb Children's Hospital, Morristown, New Jersey; 7Department of Pediatrics, Nationwide Children's Hospital, Columbus, Ohio; 8Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; 9Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin; 10Section of Gastroenterology/Hepatology/Nutrition, Riley Hospital for Children, Indianapolis, Indiana; 11Department of Gastroenterology, Dayton Children's, Dayton, Ohio; 12Division of Pediatric Gastroenterology, Nutrition and Liver Diseases, Hasbro Children's Hospital, Providence, Rhode Island; 13Department of Pediatrics, Russell Children's Hospital, Birmingham, Alabama; 14Division of Pediatric Gastroenterology and Nutrition, Johns Hopkins University School of Medicine, Baltimore, Maryland; 15Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Medical Center, Cincinnati, Ohio; 16Department of Pediatrics, University of North Carolina, Chapel Hill, North Carolina; and 17Department of Pediatrics, Cohen Children's Medical Center, New Hyde Park, New - - 2014
Methotrexate (MTX) use as an alternative to thiopurines in the treatment of Crohn's disease (CD) in children is increasing. This study was undertaken to assess safety and efficacy of MTX in children with CD. Patients treated with MTX with a minimum of 1-year follow-up were identified in the Pediatric IBD ...
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