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Results 401 - 450 of 9714
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Ezquiaga Elena E University Hospital La Princesa, Universidad Autónoma de Madrid, Madrid, Spain, - - 2014
Bipolar disorder is a highly recurrent disease which requires long-term treatment. Dropout is a major problem, poorly understood. The objectives of this study were to know the risk of dropout of a cohort of bipolar patients under ambulatory treatment and to identify the clinical profile of patients more likely to ...
Young Simon W SW 836 Peary Lane, Foster City, San Mateo, CA 94404. E-mail address: - - 2014
The rate of Achilles tendon ruptures is increasing, but there is a lack of consensus on treatment of acute injuries. The purpose of this trial was to compare outcomes of weight-bearing casts with those of traditional casts in the treatment of acute Achilles tendon ruptures.METHODS: Eighty-four patients with an acute ...
Yıldızgören Mustafa Turgut MT Department of Physical Medicine and Rehabilitation, Ankara Occupational Diseases Hospital, Ankara, Turkey, - - 2014
Effects of retinoic acid on collagen synthesis and cartilage have previously been shown. However, its effects on cartilage and tendons in humans have not been studied yet. Therefore, in order to provide a morphologic insight, the aim of this study was to measure femoral cartilage, Achilles and supraspinatus tendon thicknesses ...
Roth Eli M EM The Sterling Research Group, Cincinnati, OH, USA. Electronic address: - - 2014
Efficacy and safety of alirocumab were compared with ezetimibe in hypercholesterolemic patients at moderate cardiovascular risk not receiving statins or other lipid-lowering therapy. In a Phase 3, randomized, double-blind, double-dummy study (NCT01644474), patients (low-density lipoprotein cholesterol [LDL-C] 100-190mg/dL, 10-year risk of fatal cardiovascular events ≥1%-<5% [systemic coronary risk estimation]) were ...
Coutinho J M JM Department of Neurology of the Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands, - - 2014
Patients with recent cerebral venous sinus thrombosis (CVT) should be fully anticoagulated with heparin as soon as the diagnosis is confirmed, even in the presence of cerebral hemorrhagic venous infarcts. Fixed-dose subcutaneous low-molecular-weight heparins (LMWH) in therapeutic dosage have a better safety profile and are probably more effective than dose-adjusted ...
Schwitters A A *Epidemic Intelligence Service, Division of Global HIV/AIDS, Center for Global Health, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, - - 2014
<sec id="st1"> <title>BACKGROUND</title> The Uganda Prisons Service (UPS) is responsible for the health of approximately 32 500 inmates in 233 prisons. In 2008 a rapid UPS assessment estimated TB prevalence at 654/100 000, three times that of the general population (183/100 000). Although treatment programs exist, little is known about treatment completion in ...
Hayashi Minoru M From the *Department of Plastic and Reconstructive Surgery, †Advanced Medical Emergency and Critical Care Center, and ‡Department of Diagnostic Pathology, Japanese Maebashi Red Cross Hospital, Maebashi, Gunma; §Department of Research and Development, J-TEC, Gamagori, Aichi; and ∥Department of Plastic and Reconstructive Surgery, Showa University School of Medicine, Tokyo, - - 2014
: In Japan, the cultured epithelial autografts "JACE" was accepted as a health insurance adaptation from January 1, 2009. We examined the extensive burn wounds in 8 patients by using a combination of autograft and JACE. After debridement, we managed the wound bed preparation by using artificial dermis. The wound ...
Cranston Ross D RD From the *Department of Medicine, University of Pittsburgh, Pittsburgh, PA; †University of Pittsburgh Medical Center, Pittsburgh, PA; ‡Statistics Consulting Laboratory, Department of Biostatistics, Graduate School of Public Health, Pittsburgh, PA; and §Department of Pathology at Magee-Womens Hospital, Pittsburgh, - - 2014
To assess the efficacy of topical 80% trichloroacetic acid (TCA) to treat internal anal high-grade squamous intraepithelial lesions (HSILs) in HIV-positive individuals. All patients who attended the University of Pittsburgh Anal Dysplasia Clinic for treatment of biopsy-proven internal anal HSIL with topical TCA between July 1, 2009, and June 30, ...
Aguilar-Olivos Nancy N Medica Sur Clinic & Foundation, Mexico City, - - 2014
Background. Carvedilol appears to be more effective than propranolol in the treatment of portal hypertension in cirrhotic patients. Aim. To compare the effects of carvedilol vs. propranolol on systemic and splanchnic haemodynamics and to evaluate the adverse events associated with these treatments. Material and methods. We performed a systematic review ...
Shiffman Mitchell L ML Liver Institute of Virginia, Bon Secours Health System, Richmond and Newport News, Virginia, - - 2014
Background and aims. The histologic hallmarks of chronic HCV include inflammation and fibrosis. The impact of interferon therapy on liver histology was evaluated. Material and methods. The study population consisted of 348 patients with chronic HCV who underwent a baseline liver biopsy, received either no treatment or a single course ...
Gao Jun J *Department of Hepatobiliary Surgery, Beijing Chao-yang Hospital Affiliated to Capital Medical University, Beijing †Department of General Surgery, Zhanhua People's Hospital §Department of Gastroenterology, Dezhou People's Hospital, Shandong ‡Department of General Surgery, Chaoyang Central Hospital, Liaoning, - - 2014
Radiofrequency (RF) ablation is an accepted nonsurgical treatment of hepatic hemangiomas, but with an appreciable complication rate. Our study aimed to assess the safety and efficacy of RF ablation, administered with either multitined expandable electrodes or with internally cooled cluster electrodes, in the treatment of large (≥10 cm diameter) hepatic ...
Barnes C C Haemophilia Treatment Centre, Royal Children's Hospital, Parkville, Vic., - - 2014
Immune tolerance induction (ITI) is the preferred management of haemophilia A patients who develop high titre inhibitors against factor VIII. However, the optimal ITI regimen, predictors of ITI outcome and definitions of successful and unsuccessful ITI remain unclear. The aim of this project was to develop a consensus on the ...
Bergman Michael M Department of Internal Medicine "C" (MB, DD, NB, YO, HS), Rabin Medical Center, Hasharon Hospital, Petah-Tiqva, Israel; Sackler School of Medicine (MB, DD, NB, YO, HS), Tel-Aviv University, Ramat Aviv, Israel; and Division of Nephrology, Department of Medicine (ZZB), Beth Israel Medical Center, Albert Einstein School of Medicine of Yeshiva University, New York, New - - 2014
Oral anticoagulants (OAC) are effective in the prevention of thromboembolic events but are underused. The 1st year following the beginning of vitamin K antagonists is associated with higher bleeding rate, especially in patients with international normalized ratio (INR) of >4, leading to discontinuation of OAC. We hypothesized that the decision ...
DU Jun-Dong JD Departments of Heptapobiliary Surgery, The First Affiliated Hospital to General Hospital of PLA, Beijing 100048, P.R. - - 2014
The current study explored the effects of intensive insulin therapy (IIT) combined with low molecular weight heparin (LMWH) anticoagulant therapy on severe acute pancreatitis (SAP). A total of 134 patients with SAP that received treatment between June 2008 and June 2012 were divided randomly into groups A (control; n=33), B ...
Sandler Jonathan J Consultant orthodontist, Chesterfield Royal Hospital, Chesterfield, United Kingdom. Electronic address: - - 2014
The objective of this 3-arm parallel randomized clinical trial was to compare the effectiveness of temporary anchorage devices (TADs), Nance button palatal arches, and headgear for anchorage supplementation in the treatment of patients with malocclusions that required maximum anchorage. This trial was conducted between August 2008 and February 2013 in ...
Rocha Roberto R Adjunct professor, Department of Dentistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina, - - 2014
This case report describes the treatment and long-term follow-up care of a patient diagnosed with cleidocranial dysplasia who had multiple impacted permanent and supernumerary teeth. The aim of the treatment was to provide an adequate esthetic and functional reconstruction of the occlusion with good periodontal care. The patient was treated ...
Aiba Hisaki H Department of Orthopaedic Surgery, Nagoya City University, Nagoya, Aichi, Japan Department of Orthopaedic Surgery, Tosei General Hospital, Seto, Aichi, Japan - - 2014
Background: Osteoid osteoma is one type of benign bone tumor that may respond to conservative treatment. Patients and Methods: A retrospective study of 11 patients with osteoid osteoma was performed. Initially, patients were treated with non-steroidal anti-inflammatories (NSAIDs), unless they continued to have intolerable pain, or if the patient requested ...
Nicolas Florence F Department of Gynecology, CHU Anne de Bretagne, Rennes, Brittany, - - 2014
Objectives: To assess cervical regeneration after large loop excision of the transformation zone (LLETZ) by ultrasound (US) measurements of cervical length (CL) before conization as well as in the postoperative short- and long-term and to identify factors affecting regeneration. Patients and Methods: This was a prospective observational study including patients ...
Xu Jing - - 2014
Background and purpose: Thrombolytic treatment criteria vary significantly between China and the USA. We reviewed current intravenous (IV) thrombolytic therapy practices in China and the USA to determine the most appropriate. Methods: We conducted a systematic review of studies that used IV recombinant tissue plasminogen activator (rt-PA) therapy in China ...
Simavli Hüseyin H 1 Ophthalmology Clinic, Izzet Baysal State Hospital , Bolu, Turkey - - 2014
Abstract Purpose: To evaluate the inhibitory effects of propranolol, a nonselective and lipophilic β-adrenergic receptor blocker, on alkali-induced corneal neovascularization (NV). Methods: Corneal NV was induced in 24 eyes of 24 Wistar rats using NaOH. Following alkali burn, animals were randomized into 4 groups according to topical treatment. Group I ...
Middleton C C Royal National Orthopaedic Hospital, The Shoulder and Elbow Service, Brockley Hill, Stanmore, Middlesex, HA7 4LP, - - 2014
Inherent disadvantages of reverse shoulder arthroplasty designs based on the Grammont concept have raised a renewed interest in less-medialised designs and techniques. The aim of this study was to evaluate the outcome of reverse shoulder arthroplasty (RSA) with the fully-constrained, less-medialised, Bayley-Walker prosthesis performed for the treatment of rotator-cuff-deficient shoulders ...
Gajendran Varun K - - 2014
The authors report the case of a 65-year-old, right-hand-dominant man who had severe Dupuytren's disease with multiple cords and flexion contractures of the metacarpophalangeal and proximal interphalangeal joints of both hands and underwent repeated collagenase injections for treatment. Collagenase has been shown to be safe and effective in the treatment ...
Farhat Patrícia Bahls de Almeida PB Department of Dentistry, Universidade Estadual de Ponta Grossa (UEPG) , Paraná, Brazil - - 2014
Abstract Objective: This study determined the efficacy of LED-laser treatment and the control of sensitivity caused by in-office bleaching. Background data: Auxiliary power sources (halogen light, arc plasma, LED, LED-laser, and laser) are used in in-office teeth bleaching techniques to accelerate the redox reaction of the whitening gel to increase ...
Zheng Jun J Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, - - 2014
The management of perioperative period for patients with spontaneous intracerebral hemorrhage affects the prognosis. Elevated blood pressure is common in the patients with spontaneous intracerebral hemorrhage and related to a poor outcome. However, study on antihypertensive treatment for surgical patients with spontaneous intracerebral hemorrhage is insufficient. To determine if the ...
Levin Adriane A - - 2014
Although biologic therapies have been shown to be more effective than traditional systemic therapies in clinical trials for the treatment of psoriasis, the drug survival time and reasons for discontinuation of biologics in clinical practice have not been compared with those of conventional systemic therapies.<BR /> Retrospective, cross-sectional.<BR /> All ...
Kohorst John J - - 2014
Treatment of hidradenitis suppurativa has been studied, but treatment strategies and outcomes have not been reported for a large community-based group of patients.<BR /> We sought to determine the treatments most commonly prescribed and the performance of all systemic and surgical treatments used in hidradenitis suppurativa patients in Olmsted County, ...
Swelem Amal Ali - - 2014
Purpose: This study investigated changes in oral health-related quality of life (OHRQoL) in partially edentulous patients treated with removable dental prostheses (RDPs), fixed dental prostheses (FDPs), fixed-removable (combined) restorations (COMBs), and implant-supported fixed prostheses (ISFPs). Materials and Methods: A total of 200 patients (30 to 50 years old) were enrolled: ...
Xia Lei L From the *Department of Neurosurgery, XinHua Hospital (The Cranial Nerve Disease Center of Shanghai), Shanghai JiaoTong University School of Medicine, Shanghai, China; and †Institute of Neurosurgery, Catholic University of Rome, Rome, - - 2014
Microvascular decompression has been now accepted worldwide as a reasonable treatment for trigeminal neuralgia, yet, as a functional operation in the cerebellopontine angle, this process may be risky and the postoperative outcomes might not be good enough sometimes. To assess the effectiveness and safety of microvascular decompression for treatment of ...
Kuismanen Kirsi K Department of Obstetrics and Gynaecology and School of Medicine and - - 2014
The purpose of our study was to find out whether transurethral injections of autologous adipose stem cells (ASCs) are an effective and a safe treatment for female stress urinary incontinence (SUI). We treated five SUI patients with ASCs combined with bovine collagen gel and saline. Prior to the treatment, the ...
O'Callaghan Adrian A Department of Vascular and Endovascular Surgery, Cleveland Clinic Foundation, Cleveland, - - 2014
Endovascular options for the treatment of proximal thoracic and arch disease have evolved over the years. In this manuscript, we review the midterm results of fenestrated compared with chimney configurations for proximal aortic aneurysm disease. We performed an analysis of all patients with chimney grafts or custom fenestrated endografts used for ...
Munang Melinda M Birmingham Heartlands Hospital, Department of Infection and Tropical Medicine - - 2014
Background: There have been few studies on risk factors and treatment outcomes of isoniazid (H)-resistant tuberculosis (TB) and optimal treatment regimens are debated. Aim: To identify risk factors for H-resistant TB, describe treatment regimens and compare these to national guidelines and describe short-term outcomes of H-resistant TB in Birmingham, United ...
Yi Yong Jin YJ Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of - - 2014
Evening administration of the conventional immediate-release (IR) formulation of simvastatin is recommended because of its short half-life (1.9 hours). In a healthy population, morning administration of a controlled-release (CR) formulation of simvastatin was shown to have equivalent lipid-lowering efficacy and a safety profile similar to that of evening doses of ...
Kissin Eugene Y EY Division of Rheumatology, Boston University School of Medicine, Boston, Massachusetts. Electronic address: - - 2014
The European League Against Rheumatism (EULAR) recently updated its recommendations on the management of rheumatoid arthritis (RA) with synthetic and disease-modifying antirheumatic drugs (DMARDs), motivated by the availability of new treatment options over the past 3 or 4 years. Modifications since 2010 include the removal of the recommendation of the ...
Yarboro Douglas D DD The Wound Care Center of Northern Hospital of Surry County, Mount Airy, NC; email: dougyarboro@ - - 2014
Transcutaneous electrical nerve stimulation (TENS) is used to alleviate muscle pain, and there is some evidence it may affect healing in chronic wounds. An 80-year-old male patient with a chronic left lower extremity wound and a history of peripheral arterial disease, type 2 diabetes, hypertension, chronic obstructive pulmonary disease, and ...
Sanatkhani Majid M Oral and Maxillofacial Diseases Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, - - 2014
Oral Lichen Planus (OLP) is a chronic mucocutaneous disease with an immunological etiology. This study was conducted to evaluate the effect of cedar honey in the treatment of erosive- atrophic OLP. Thirty patients with a confirmed clinical and histopathologic diagnosis of OLP participated in this randomized clinical trial in Mashhad ...
Selid Paul D - - 2014
To compare treatment of exudative age-related macular degeneration (AMD) with bevacizumab versus aflibercept in terms of central retinal thickness (CRT) and best corrected visual acuity (BCVA). A retrospective cohort study examining changes in CRT and BCVA over 12 months of follow-up in 111 patients treated with bevacizumab and 91 treated ...
Nambiar Arjun A Department of Urology, Morriston Hospital, Swansea, United - - 2014
This chapter focuses on the position of botulinum toxin type A in the treatment pathway for overactive bladder (OAB) and neurogenic lower urinary tract dysfunction associated with neurogenic detrusor overactivity (NDO), and the recommendations of the major international guideline groups. Recommendations of different guideline groups may vary, especially when evidence ...
Ebnezar John J Ebnezar Orthopedic Center, Bengaluru, Karnataka, - - 2014
OA Knee is the most common arthritis. Knee replacement Surgeries are being done increasingly in the present times. This has led to the violation of the standard indications and when knees are replaced ignoring other co - musculoskeletal conditions it results in the surgery failing early. This is about a ...
Anchala Praveen R - - 2014
Spinal metastatic lesions are a common occurrence among oncology patients and contribute to significant morbidity. Treatment options have been limited in their effectiveness and scope to this point. This study aims to report the safety and efficacy of radiofrequency ablation (RFA) of malignant spinal lesions using a novel RFA bipolar ...
Park Sang Woo SW Department of Radiology, Konkuk University Hospital, Konkuk University School of Medicine, Seoul 143-729, - - 2014
To compare the efficacy and adverse effects of endovenous foam sclerotherapy (EFS) and liquid sclerotherapy (ELS) using a microcatheter for the treatment of varicose tributaries. From December 2007 to January 2009, patients with venous reflux in the saphenous vein were enrolled. The foam or liquid sclerosant was injected through a ...
Noaiseh Ghaith G Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. - - 2014
There are currently no head-to-head comparisons of sialagogues for Primary Sjögren's syndrome (pSS). We compared the tolerability and side effect profile of pilocarpine and cevimeline in patients with pSS and determined clinical, laboratory and pathological variables associated with therapeutic failure. We retrospectively reviewed the use of pilocarpine and cevimeline in ...
Vidal G G Neurology, Radiology and Neurosurgery, Ochsner Clinic Foundation, New Orleans, LA, - - 2014
Most patients with large vessel occlusion (LVO) present with high NIHSS, and it has been shown that initial NIHSS is a predictor of outcomes in patient with acute ischemic stroke. The usefulness of neuroendovascular reperfusion has been a controversial topic. The aim of this study was to compare the outcomes ...
Chalouhi N N Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, PA, - - 2014
Stenting techniques such as stent-assisted coiling and flow diversion are increasingly used for treatment of intracranial aneurysms. In previous reports, patients were pretreated were aspirin and clopidogrel prior to the intervention for prevention of thromboembolic complications. Prior studies also often rely on aspirin response and P2Y assessment, which often delays ...
Park M M Neurological Surgery, Barrow Neurological Institute, Phoenix, AZ, - - 2014
The Pipeline Embolization Device (PED, eV3 Neurovascular, Irvine, California) has increased the ability of the neurointerventionalist to treat progressively more difficult cerebrovascular pathology. We sought to determine the efficacy of the PED in the treatment of the most recalcitrant of aneurysms, those aneurysms recurring after previous treatments. We retrospectively queried ...
Turk A A 3rd NeuroEndovascular Surgery, Medical University of South Carolina, Charleston, SC, - - 2014
The use of mechanical thrombectomy for treatment of acute ischemic stroke has significantly advanced over the last 5 years. Little data is available analysing the cost relative to the clinical and angiographic outcomes. The aim of this study is to analyze the cost and efficacy of current stroke therapy. A ...
Pierot L L Radiology, Hôpital Maison-Blanche, Reims, - - 2014
To evaluate the feasibility, safety, and efficacy of endovascular treatment with flow diverters (FD) in patients with recanalised and multitreated aneurysms, in a retrospective, multicenter, single-arm study. The study included 29 patients with 29 recanalised aneurysms who were treated by FDs (Silk or Pipeline device). Per and post procedural complications ...
Alexander M M Radiology, Santa Clara Valley Medical Center, San Jose, CA, - - 2014
Endovascular treatment of intracranial atherosclerotic disease is controversial, and optimal treatment remains unclear. Acute ischemic stroke (AIS) due to thrombosis of an in situ stenosis has undergone little investigation. Infarction from such disease in the posterior circulation causes pronounced morbidity. We reviewed outcomes of patients undergoing endovascular treatment of AIS ...
Robert T T Interventional Neuroradiology, Rothschild Foundation Hospital, Paris, - - 2014
Arteriovenous malformations (AVM) of the corpus callosum were rare lesions, accounting for 9-11% of brain AVMs. Microsurgical resection of such lesions remained difficult regarding deep location and possible neuropsychological disasters of extended callosal resection. The introduction of endovascular and radiation therapies fundamentally changed the outcome of these lesions. Since 1995, ...
Alexander M M Radiology, University of Washington, Seattle, CA, - - 2014
Intracranial atherosclerotic disease (ICAD) is often stratified by degree of stenosis. Additional features such as patient demographics and symptom characteristics also affect lesion behavior and response to treatment. This study compares stratification by degree of narrowing to these additional features. Retrospective analysis was performed on patients at 4 hospitals with ...
Chowdhary A A Director of Neurosurgery and Neuro-Interventional Surgery, Overlake Hospital, Bellevue, WA, - - 2014
Radiation exposure during an angiographic procedure may present a significant health risk to patients. The goal of this multicenter case study (CARE) is to compare such exposure in patients treated with the novel Penumbra Coil 400™ System (PC 400) vs. conventional coils. The PC 400 coils are a new generation ...
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