Search Results
Results 301 - 350 of 9473
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Zeng Teng T Institute for Viral Hepatitis, Key Laboratory of Molecular Biology for Infectious Diseases, Ministry of Education, Second Affiliated Hospital of Chongqing Medical University, Chongqing, China. - - 2014
To determine whether adefovir (ADV) in combination with entecavir (ETV) is more effective than with lamivudine (LAM) in patients with lamivudine-resistant chronic HBV infection, electronic databases were searched through May 10th, 2013 to obtain relevant trials which met the inclusion criteria. Meta-analysis was performed on randomized controlled trials (RCTs) and ...
Grip O O Uppsala University, Department of Surgical Sciences, Section of Vascular Surgery, Uppsala, Lund University, Department of Clinical Sciences Malmö, - - 2014
Thrombolysis is a common treatment for acute leg ischaemia. The purpose of this study was to evaluate different thrombolytic treatment strategies, and risk factors for complications. This was a retrospective analysis of prospective databases from two vascular centres. One centre used a higher dose of heparin and recombinant tissue plasminogen ...
Peng Ke K Department of Anesthesiology, First Affiliated Hospital of Soochow University, No. 188 Shizi Street, Suzhou 215006, Jiangsu Province, - - 2014
This meta-analysis aimed to systematically collect the current evidence regarding the efficacy and safety of dexmedetomidine (DEX) as an anesthetic adjuvant for patients undergoing intracranial surgery. A systematic literature search of randomized controlled trials (RCT) was conducted to compare DEX with placebo or opioids in patients undergoing intracranial procedures. Hemodynamic ...
O'Brart David Ps DP Keratoconus Research Institute, Department of Ophthalmology, St. Thomas' Hospital, London SE1 7EH, United Kingdom. Electronic address: - - 2014
To investigate 20 year efficacy and safety of Photorefractive Keratectomy (PRK) DESIGN: Long-term observational case series. University Hospital STUDY POPULATION: Forty-two patients (42 eyes) who had as part of a randomized, prospective trial undergone PRK 20 years previously are presented. All had received -3.0 or -6.0 diopter (D) corrections with ...
Calabrese Edward J EJ Department of Public Health, Environmental Health Sciences, Morrill I, N344, University of Massachusetts, Amherst, MA, 01003, USA, - - 2014
This article assesses the therapeutic efficacy of ionizing radiation for the treatment of shoulder tendonitis/bursitis in the USA over the period of its use (human 1936-1961; veterinary 1954-1974). Results from ~3,500 human cases were reported in the clinical case studies over 30 articles, and indicated a high treatment efficacy (>90 %) ...
Zargar Homayoun H Cleveland clinic , 9500 Euclid ave , Cleveland, Ohio, United States, 44125 ; - - 2014
Purpose: To compare the perioperative outcomes of RPN with OPN in solitary kidneys. Methods: Records of 1542 consecutive RPN performed in 5 high volume centres (2007-2013) were reviewed for patients with solitary kidneys. Results were compared with solitary OPN cases performed during the same period. Cases were divided into simple ...
Darvall K A L KA Birmingham University Department of Vascular Surgery, Flat 5 Netherwood House, Solihull Hospital, Lode Lane, Solihull, B91 2JL, - - 2014
The aim was to determine the long-term (5-8 years) outcomes of ultrasound-guided foam sclerotherapy (UGFS) for varicose veins using health-related quality of life (HRQL), patient-reported outcomes (PROMs), patient satisfaction and retreatment rates. Consecutive patients undergoing UGFS between April 2004 and May 2007 were invited for review at least 5 years after treatment. ...
Botsios Spiridon S Center of Vascular Medicine, Angiology and Vascular Surgery, Park Hospital Leipzig, Leipzig, Germany Faculty of Health, Witten/Herdecke University, Witten, Germany - - 2014
Endovascular treatment of the infrarenal abdominal aorta (endovascular repair, EVAR) has emerged as an alternative to open surgery. However, a small subset of patients exists who undergo conversion either in the first 30 postoperative days or later during the course of postoperative surveillance. In the present study, we review our ...
Nakamura Junichi J *Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University †Chiba Children and Adult Orthopaedic Clinic ‡Division of Orthopaedic Surgery, Chiba Children's Hospital, Chiba City, Chiba, - - 2014
The prognosis of Legg-Calvé-Perthes disease (LCPD) in young patients has been accepted as favorable. The purpose of this study was to clarify the outcome of LCPD patients with onset before 6 years of age. From 1989 to 2007, of 332 LCPD patients, 114 hips (in 100 patients) were diagnosed before ...
Tiruveedhula Madhu M *University Hospital Southampton Foundation Trust; Southampton General Hospital †NIHR Research Design Service South Central ‡University of Southampton and Child Health, University Hospital Southampton Foundation Trust, Southampton General Hospital, Southampton, - - 2014
Avascular necrosis (AVN) of the femoral head is an irreversible complication seen in the treatment of developmental dysplasia of hip (DDH) with the Pavlik harness. Its incidence is reported to be low after successful reduction of the hip but high if the hip is not concentrically relocated. We aim to ...
Geisbüsch Christina C From the Departments of Neurology (C.G., D.R., P.A.R., S.N.) and Neuroradiology (C.H.), University of Heidelberg, Heidelberg, - - 2014
Thrombosis of cerebral veins and sinus (cerebral venous thrombosis) is a rare stroke pathogenesis. Pharmaceutical treatment is restricted to heparin and oral anticoagulation with vitamin K antagonists (VKAs). Between January 2012 and December 2013, we recorded data from our patients with cerebral venous thrombosis. The modified Rankin scale was used ...
Bots Michiel L ML From the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands (M.L.B.); Robertson Centre for Biostatistics, University of Glasgow, Glasgow, United Kingdom (I.F., S.M.L.); Department of Pharmacology and INSERM U970, Hôpital Européen Georges Pompidou, Paris, France (S.L.); Department of Neurology and Stroke Center, Hôpital Bichat and INSERM U698, Paris, France (P.J.T.); and Department of Neurology, UMM, University of Heidelberg, Mannheim, Germany (M.G.H.). - - 2014
Thromboxane prostaglandin receptors have been implicated to be involved in the atherosclerotic process. We assessed whether Terutroban, a thromboxane prostaglandin receptor antagonist, affects the progression of atherosclerosis, as measured by common carotid intima-media thickness and carotid plaques. A substudy was performed among 1141 participants of the aspirin-controlled Prevention of Cerebrovascular ...
Wu Nan N Department of Pathology and Internal Medicine, College of Medicine, Ohio State University, Columbus, - - 2014
Thrombotic thrombocytopenic purpura (TTP) requires immediate treatment with plasma exchange (PE) to prevent disease mortality and/or morbidity. Frequently, PE is initiated before blood sample is collected to confirm ADAMTS13 deficiency. However, the effect of PE treatments on the evaluation of ADAMTS13 is uncertain. Moreover, the pertinence of ADAMTS13 activity during ...
Song Zhen Guo ZG Department of Pancreatic Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China; Department of Anesthesiology and Operating Center, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, - - 2014
This study aimed to investigate the efficacy and safety of palliative bypass surgery combined with cryoablation to treat patients with advanced pancreatic cancer and compare them with those of palliative bypass surgery alone. Medical records of 118 patients with advanced pancreatic cancer who received palliative bypass surgery combined with cryoablation ...
Nery Caio C Foot and Ankle Clinic, UNIFESP-Federal University of São Paulo, Escola Paulista de Medicina, São Paulo, SP, Brazil - - 2014
Instability of the lesser metatarsophalangeal (MTP) joints is a common cause of deformity and pain. The purpose of this study was to prospectively evaluate the surgical outcomes for the different grades of plantar plate tears and propose a treatment protocol. Sixty-eight patients (100 MTP joints) were prospectively enrolled and graded ...
Bifulco G G Department of Gynaecology and Obstetrics, and Pathophysiology of Human Reproduction, University of Naples "Federico II," Naples, Italy. Via Pansini 5, 80131 Naples, - - 2014
lymphoceles are among the most common postoperative complications of pelvic lymphadenectomy , with a reported incidence of 1% to 29% in gynecology oncology. Several studies evaluated the effectiveness of biological glues on reducing lymphoceles,but no data on gynecological patients are available.We evaluated the effectiveness of cyanoacrylic glues (n-butyl cyanoacrylate) ( ...
Kepler Christopher K CK Rothman Institute/Thomas Jefferson University, Department of Orthopaedic - - 2014
Study Design. Retrospective ReviewObjective. 1) To describe change in treatment patterns for Degenerative Spondylolisthesis (DS). 2) To report regional variation in treatment of DS. 3) To describe variation in surgeon-reported outcomes for DS based on treatment.Summary of Background Data. Spinal stenosis associated with DS is commonly treated with decompression and ...
Yang Haisong H Department of Orthopedic Surgery, Changzheng Hospital, Shanghai, - - 2014
Study Design. Retrospective case series study.Objective. To clarify the results of a long-term (30 years) follow-up study of artificial disc replacement (ADR) for the treatment of cervical disc disease.Summary of Background Data. The use of the ADR procedure has become widespread over the past 10 years. Its purpose is to ...
Thomas G P GP The Sir Alan Parks Department of Physiology, St Mark's Hospital and Academic Institute, Watford Road, Harrow, Middlesex, HA1 3UJ, - - 2014
Sacral nerve stimulation (SNS) is used as a first-line treatment for faecal incontinence when conservative measures have failed. However, one-third of patients fail to benefit from this treatment. We hypothesised that sacral afferent stimulation can be maximised using pudendal nerve stimulation (PNS) and this may be of benefit in this ...
Li Shuang - - 2014
We investigated the long-term effects and safety of botulinum toxin-A (BTX-A) for treating trigeminal neuralgia (TN). We also studied long-term maintenance of this therapeutic effect. A visual analog scale (VAS) score, pain attack frequency per day, patient's overall response to treatment and side effects during 14-month follow-up were evaluated in ...
Du Y Y The Department of Neurosurgery, The First People's Hospital of Hangzhou, Nanjing Medical University, 261 Huanshan Road, Hangzhou, 310000, - - 2014
Although microvascular decompression (MVD) has become the best surgical treatment for trigeminal neuralgia, it does not achieve 100 % cure rate. Re-exploration of the posterior fossa may carry increased risk over first-time MVD and is not always successful, so other treatments are needed. In this study, we evaluate the effectiveness of ...
Mancini Donato D Department of Orthopaedic Surgery, Federico II University, Naples, - - 2014
This study assesses and compares the clinical outcomes of the arthroscopic matrix-induced autologous chondrocyte implant (MACI) and autologous matrix-induced chondrogenesis (AMIC) techniques for the treatment of acetabular chondral defects between 2 and 4 cm(2) consequent to femoral acetabular impingement. Fifty-seven consecutive patients were treated with the MACI (n = 26) or AMIC (n = 31) ...
Strauss Adam C AC Department of Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA, - - 2014
Radiofrequency ablation (RFA), with or without endoscopic mucosal resection (EMR), has been validated as a safe, effective and durable treatment option for dysplastic Barrett's esophagus. Its durability in eradicating Barrett's-associated intramucosal carcinoma (IMC), however, is unclear. We set out to assess the long-term safety and efficacy of RFA for IMC. ...
Yang YaLi Y Department of Dermatology, Changzheng Hospital, Second Military Medical University, 415 Fengyang Road, Shanghai, - - 2014
To summarize the epidemiology, clinical features, treatment, and outcome of cryptococcal meningitis (CM) in autoimmune hemolytic anemia (AIHA) patients and to provide a reference for the prevention and control of AIHA complicated with CM, we evaluated five cases of CM in patients with AIHA treated in our hospital from 2003 ...
Park Tai Hwan TH Department of Neurology, Seoul Medical Center, Seoul, - - 2014
The safety and efficacy of intravenous tissue plasminogen activator (IV-TPA) in the 3- to 4.5-hour window were largely driven from Western populations, but have not been systematically explored in Korean population. We compared outcomes of acute ischemic stroke patients treated in the 3- to 4.5-hour window versus those in the ...
Tudorache Elena E Department of Paediatric Nephrology, Armand-Trousseau Hospital, APHP, Paris, France; University Pierre and Marie Curie, Paris 6, - - 2014
Henoch Schonlein purpura (HSP) is a common cause of paediatric renal disease in children, representing 10-15% of paediatric glomerulonephritis. This study examined the long-term outcome of biopsy proven HSP nephritis to identify correlations between disease development and treatment. Patients from three French centres were retrospectively analysed. We followed up 142 ...
Keino H H Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, - - 2014
PurposeTo evaluate the effect of infliximab over the initial 4 years of treatment on inflammatory ocular attacks and background retinal/disc vascular leakage in patients with refractory uveoretinitis associated with Behçet's disease.MethodsClinical records of nine patients were retrospectively reviewed. The main outcomes analyzed were frequency of ocular inflammatory attacks, background retinal ...
Gubler Christoph C Clinic of Gastroenterology and Hepatology, University Hospital of Zurich , Zurich , - - 2014
Abstract Objective. Optimal endoscopic treatment of gastric varices is still not standardized nowadays. Actively bleeding varices may prohibit a successful endoscopic injection therapy of Histoacryl® (N-butyl-2-cyanoacrylate). Since 2006, we have treated gastric varices by standardized endoscopic ultrasound (EUS) guided Histoacryl injection therapy without severe adverse events. Material and methods. We ...
Snyder Laura A LA Division of Neurological Surgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, - - 2014
Object Isthmic spondylolysis can significantly decrease functional abilities, especially in adolescent athletes. Although treatment can range from observation to surgery, direct screw placement through the fractured pars, or Buck's procedure, may be a more minimally invasive procedure than the more common pedicle screw-hook construct. Methods Review of surgical databases identified ...
Suhler Eric B EB Portland Veterans Administration Medical Center, Portland, Oregon; Oregon Health & Science University, Department of Ophthalmology/Casey Eye Institute, Portland, Oregon; Department of Public Health and Preventive Medicine, Oregon Health & Science University, Portland, Oregon. Electronic address: - - 2014
To determine whether rituximab, a monoclonal antibody against the B-lymphocyte antigen CD20, is effective in the treatment of refractory noninfectious scleritis. Prospective, dose-ranging, randomized, double-masked phase I/II clinical trial. Twelve patients with noninfectious scleritis refractory to systemic corticosteroid and ≥1 other systemic immunosuppressive agent were enrolled from January 2007 to ...
Komura Kazumasa K Department of Urology, Osaka Medical College, Osaka, Japan. Electronic address: - - 2014
To assess whether bipolar transurethral resection of the prostate using the TURis (Olympus, Tokyo, Japan) system demonstrates comparable efficacy and safety reporting 36 months of follow-up findings. The trial was registered at University hospital Medical Information Network Clinical Trials Registry in Japan (trial number UMIN 000010801). Patients were randomly selected to ...
Carrasco-Chinchilla Fernando F Unidad del Corazón, Hospital Universitario Virgen de la Victoria, Málaga, - - 2014
Symptomatic mitral regurgitation has an unfavorable prognosis unless treated by surgery. However, the European registry of valvular heart disease reports that 49% of patients with this condition do not undergo surgery. Percutaneous treatment of mitral regurgitation with MitraClip(®) has been proved a safe, efficient adjunct to medical treatment in patients ...
Coronel María Lorena ML Servicio de Neumología y Alergia Respiratoria, Institut Clínic del Tòrax, Hospital Clínic, Barcelona, España; División de Insuficiencia Cardíaca e Hipertensión Pulmonar, Instituto de Cardiología de Corrientes, Corrientes, - - 2014
Pulmonary endarterectomy (PE) is the treatment of choice for chronic thromboembolic pulmonary hypertension (CTEPH). The aim of this study was to analyze our experience in the medical and surgical management of CTEPH. We included 80 patients diagnosed with CTEPH between January 2000 and July 2012. Thirty two patients underwent PE ...
Pedrajas J M JM Servicio de Medicina Interna, Hospital Clínico San Carlos, Madrid, España. Electronic address: - - 2014
The Computerized Registry of Patients with Venous Thromboembolism (RIETE) is a prospective registry that consecutively includes patients diagnosed with venous thromboembolism. We compared the clinical presentation and response to anticoagulant treatment in patients with idiopathic venous thromboembolism (IVT) versus secondary venous thromboembolism (SVT, associated with a risk factor). We analyzed ...
Blaschi Wanessa - - 2014
Synchronization of estrus and ovulation is a reproductive technology of paramount importance in modern livestock improvement programs. It has a critical role for the implementation of assisted reproduction technologies that could increase productivity, including artificial insemination and embryo transfer. To this end, the aim of this study was to evaluate ...
Weitoft Tomas - - 2014
Intra-articular glucocorticoid treatment (IAGC) is widely used for symptom relief in arthritis. However, knowledge of factors predicting treatment outcome is limited. The aim of the present study was to identify response predictors of IAGC for knee synovitis in patients with rheumatoid arthritis (RA). In this study 121 RA patients with ...
Chaudry Gulraiz G Vascular Anomalies Center, Boston Children's Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA, 02115, USA, - - 2014
Sclerotherapy is the mainstay of treatment of macrocystic lymphatic malformation (LM), but the response using traditional sclerosants is much less beneficial in microcystic lesions. Intralesional bleomycin has been reported to be effective in microcystic LM; however, its use is limited by concerns about pulmonary fibrosis. The purpose of this study ...
Cavallini A A - - - 2014
Endovenous laser treatment (EVLT) is an accepted form of axial vein ablation for symptomatic venous reflux but its role in the treatment of anterior accessory saphenous vein (AASV) has not been well characterized. The aim of this paper is to show the short--term result of EVLT with a ball--tipped fiber ...
Guarnera G G IDI--IRCCS, Rome, Italy - - - 2014
No study of strong methodology could be found to resolve the controversy of optimal treatment of distal deep venous thrombosis (DDVT). Some inconclusive evidence exists on two approaches to care: anticoagulants and compression therapy or compression therapy and duplex scanning monitoring. Different studies report propagation to popliteal vein in 8% ...
Jevalikar Ganesh - - 2014
Abstract Background: Remission rates with antithyroid drugs (ATDs) in pediatric Graves' disease (GD) are low. Very few studies report long-term follow-up of GD especially into adulthood. Objectives: We studied long-term outcomes of pediatric onset GD, including a follow-up into adulthood and factors associated with need for definitive therapy. Methods: Sixty-five ...
Marinschek Sabine S Department for General Paediatrics and Psychosomatic, Medical University of Graz, Graz, Styria, - - 2014
The Graz model of tube weaning has been internationally recognised as a successful and rapid tube weaning program. Beside the onsite treatment option, a telemedical counselling was specifically developed in 2009. This study aims to show outcomes of this newly invented treatment in a large sample of patients. Our retrospective ...
Raymond J J From the Department of Radiology (J.R., A.W., F.G., D.R.), Centre Hospitalier de l'Université de Montréal and Laboratory of Interventional Neuroradiology (J.R., R.K.), Centre de recherche du Centre Hospitalier de l'Université de Montréal, Notre-Dame Hospital, Montreal, Quebec, Canada; Département de mathématiques et de statistique (M.C.), Université de Montréal, Montreal, Quebec, Canada; Department of Neurological Surgery (S.L.B.), Oregon Health & Science University, Portland, Oregon; Department of Radiology and Medical Imaging (A.J.E.), University of Virginia Health System, Charlottesville, Virginia; Department of Neurosurgery (J.M., B.L.H.), University of Florida, Gainesville, Florida; Departments of Radiology and Neurosurgery (A.S.T., R.D.T.), Medical University of South Carolina, Charleston, South Carolina; Service de Neuroradiologie Diagnostique et Interventionnelle (H.D.), Centre Hospitalier Universitaire de Nantes, Nantes, France; Department of Neurological Surgery (D.F.), Stony Brook University Medical Center, Stony Brook, New York; and Département de Neuroradiologie Diagnostique et Interventionnelle (S.B.), Centre Hospitalier Universitaire de Nancy, Nancy, France. - - 2014
Some patients with large or recurrent aneurysms may be at increased risk of recurrence postcoiling. The Patients Prone to Recurrence after Endovascular Treatment (PRET) trial was designed to assess whether hydrogel coils were superior to platinum coils in these high-risk patients. This article reports periprocedural safety and operator-assessed angiographic results ...
Aagaard E E Department of Oral and Maxillofacial Surgery, Odense University Hospital, Odense, Denmark. Electronic address: - - 2014
This study describes the clinical variables in 61 patients following total alloplastic temporomandibular joint reconstruction (TJR) in which the Biomet Microfixation Patient-Patient-Matched TMJ Implant was used. All patients were classified using the Wilkes classification. The visual analogue scale score for jaw pain intensity, the maximum inter-incisal opening (MIO), and the ...
Filardo Giuseppe G II Orthopaedic and Traumatology Clinic - Biomechanics and Technology Innovation Laboratory, Rizzoli Orthopaedic Institute, Bologna, - - 2014
Chronic Achilles tendinopathy is responsible for a severe reduction in physical performance and persistent pain. There is currently a number of therapeutic options and the local administration of growth factors is an emerging treatment strategy. In particular, platelet-rich plasma (PRP) is a widely used way to provide a local regenerative ...
Lévy Samuel S Aix-Marseille Université, 2 Place Delibes, 13008, Marseille, France, - - 2014
New oral anticoagulants (NOACs) have emerged as an alternative therapy to warfarin in the treatment of arterial and venous thromboembolism and in stroke prevention in patients with non-valvular atrial fibrillation (AF). Three of them, i.e., dabigatran, rivaroxaban, and apixaban, have been approved for clinical use in North America and in ...
Klekamp Jörg J Department of Neurosurgery, Christliches Krankenhaus, Danziger Str. 2, 49610, Quakenbrück, Germany, - - 2014
Basilar invagination is a rare craniocervical malformation which may lead to neurological deficits related to compression of brainstem and upper cervical cord as well as instability of the craniocervical junction. This study presents results of a treatment algorithm developed over a 20-year period focussing on anatomical findings, short-term and long-term ...
Teitelbaum Ezra N EN Department of Surgery, Northwestern University Feinberg School of Medicine, 676 North Saint Clair Street, Chicago, IL, 60611, USA, - - 2014
Peroral esophageal myotomy (POEM) is a new endoscopic operation for the treatment of achalasia. Here, we report 1-year physiologic and symptomatic outcomes following the procedure. POEM patients from a single-institution series who were more than 1 year removed from surgery were studied. Eckardt and GerdQ scores were obtained to assess symptoms. ...
Laver Lior L Department of Orthopaedic Surgery, Sports Medicine Unit, "Meir" Medical Center, The Sackler School of Medicine (Tel-Aviv University), Kfar-Saba, Israel, - - 2014
Syndesmotic sprains are uncommon injuries that require prolonged recovery. The influence of ultrasound-guided injections of platelet-rich plasma (PRP) into the injured antero-inferior tibio-fibular ligaments (AITFL) in athletes on return to play (RTP) and dynamic stability was studied. Sixteen elite athletes with AITFL tears were randomized to a treatment group receiving ...
Tahar Rachida R Unité Mixte de Recherche 216 Mère et Enfant Face aux Infections Tropicales, Institut de Recherche pour le Développement (IRD), Unité de formation et de recherche (UFR) de Pharmacie, 75270 Paris, France Laboratoire de Recherche sur le Paludisme, Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale (OCEAC), B.P. 288, Yaoundé, - - 2014
 Artemisinin-based combination therapies (ACTs) are recommended for the treatment of acute uncomplicated falciparum malaria in many endemic countries. Despite the emergence of artemisinin resistance, few alternative non-ACTs, including atovaquone-proguanil, are currently available.  Plasmodium falciparum-infected Cameroonian children≤5 years old (n=338) were randomized to artesunate-amodiaquine, atovaquone-proguanil, or artesunate-atovaquone-proguanil treatment groups and followed ...
Flachenecker Peter P Neurological Rehabilitation Centre Quellenhof, Bad Wildbad, - - 2014
Background: Nabiximols (Sativex®), in a cannabinoid-based oromucosal spray, is an add-on therapy option for patients with moderate to severe multiple sclerosis spasticity (MSS) resistant to other medications. The study objective was to provide long-term data on clinical outcomes, tolerability, quality of life and treatment satisfaction for MSS patients receiving nabiximols ...
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