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Results 301 - 350 of 9713
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Milinkovic I I Department of Periodontology, Belgrade School of Dentistry, Belgrade, - - 2014
Gingival recession is defined as soft and hard tissue displacement resulting in root surface exposure. The optimal outcome of gingival recession treatment is complete, predictable and long-lasting root coverage with a significant level of tissue regeneration. Tissue engineering, which applies active regeneration principles, presents the contemporary treatment approach in the ...
Tomomatsu N N Department of Maxillofacial Surgery, Tokyo Medical and Dental University, - - 2014
Odontogenic maxillary sinusitis (OMS) is an inflammatory disease caused by the spread of dental inflammation into the sinus. The long-term administration of antibiotic medicine and/or treatment of the causative tooth are the usual initial treatments. These initial treatments are not always effective, and the reason is not well understood. The ...
Hornung B R BR Pelvic Floor Service, Department of General Surgery, University Hospital South - - 2014
Sacral nerve stimulation (SNS) is effective for some patients with faecal incontinence. Before insertion of a costly implant, percutaneous nerve evaluation (PNE) is undertaken to identify patients likely to report success from SNS. The aim of this study was to determine whether variables of anal sphincter function measured by anal ...
Lizaur-Utrilla Alejandro A Department of Orthopaedic Surgery, Elda University Hospital, Elda, Alicante, - - 2014
The aim was to identify patient-related predictors of treatment failure after primary total knee arthroplasty for osteoarthritis. Treatment failure included surgical revision or clinical failure, which was defined by less than 70 in any score of the Knee Society. Prospective follow-up was performed in 412 consecutive patients with a minimum ...
Uyeturk Ugur U Abant Izzet Baysal University Faculty of Medicine, Department Of Urology , A.I.B.U. Uroloji Bolu , Bolu, Turkey , 14000 ; - - 2014
Objective:Mitomycin C (MMC), bevacizumab, and 5-fluorouracil (5-FU) are frequently used in cancer treatment. Each of these agents also exhibits antiproliferative properties in different tissues. We compared the efficacy of MMC, bevacizumab, and 5-FU for the prevention of urethral stricture (US). Materials and Methods: Forty male rabbits with traumatized urethras were ...
Ziemlewicz Timothy J TJ Department of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, E3/366, Madison, WI, 53792-3252, USA, - - 2014
This study was designed to explore the safety and efficacy of percutaneous microwave (MW) ablation as an alternative treatment for symptomatic giant hepatic hemangiomas. Patients (n = 7; 6 females, 1 male; mean age = 44 years) with symptomatic, giant hemangiomas (n = 8) were treated with ultrasound-guided percutaneous MW ablation and followed for a mean of ...
Dos Santos Aretha Aliny Ramos AA a Master's student, Graduate Program in Dentistry, Federal University of Paraíba, João Pessoa, PB, - - 2014
Abstract Objective: To test the hypothesis that treatment time, debris/biofilm, and oral pH have an influence on the physical-chemical properties of orthodontic brackets and arch wires. Materials and Methods: One hundred twenty metal brackets were evaluated. They were divided into four groups (n  =  30) according to treatment time: group ...
Turk Aquilla S AS Department of Radiology and Radiological Sciences, Medical University of South Carolina, Charleston, South Carolina, - - 2014
The use of mechanical thrombectomy for the treatment of acute ischemic stroke has significantly advanced over the last 5 years. Few data are available comparing the cost and clinical and angiographic outcomes associated with available techniques. The aim of this study is to compare the cost and efficacy of current endovascular ...
Lee Young-Jun YJ From the Department of Medical Imaging (Y.-J.L., K.G.T., G.S., T.K.), and Division of Neurosurgery (T.K.), Toronto Western Hospital, University of Toronto, Ontario, Canada; Department of Radiology, Hanyang University Hospital, Hanyang University College of Medicine, Seoul, Korea (Y.-J.L.); and Service de Neuroradiologie, CHU Bicêtre, Le Kremlin Bicêtre Cedex, France - - 2014
As a result of the rarity of spinal cord arteriovenous malformations (AVM), there are only a few series available that describe clinical features, outcome after treatment, and natural history of these lesions. In this article, we aim to describe our experience with both nidus- and fistulous-type spinal cord AVMs. Forty-four ...
Song In-Ho IH From the Department of Rheumatology and the Department of Radiology, Charité Medical University, Campus Charité Mitte, Berlin; German Rheumatism Research Center, Berlin, Germany; Division of Rheumatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Pfizer; Schlosspark-Klinik; Endokrinologikum, Berlin, Germany. Supported by an unrestricted grant from Pfizer. Pfizer provided financial support and provided the study drug etanercept. I-H. Song, Rheumatology, Charité Medical University; K-G. Hermann, Department of Radiology, Charité Medical University; H. Haibel, Rheumatology, Charité Medical University; C.E. Althoff, Department of Radiology, Charité Medical University; D. Poddubnyy, Rheumatology, Charité Medical University; J. Listing; A. Weiß, German Rheumatism Research Center; B. Buß, Rheumatology, Charité Medical University; B. Freundlich, Division of Rheumatology, University of Pennsylvania; E. Lange, Pfizer; R. Alten, Schlosspark-Klinik; M. Rudwaleit, Rheumatology, Charité Medical University, and Endokrinologikum; J. Sieper, Rheumatology, Charité Medical University. Address correspondence to Dr. J. Sieper, Charité, Campus Benjamin Franklin, Med. Clinic I, Rheumatology, Hindenburgdamm 30, 12203 Berlin, Germany. E-mail: joachim.sieper@charite.de. Accepted for publication May 15, - - 2014
In patients with early active axial spondyloarthritis (axSpA) with a disease duration of < 5 years, the longterm efficacy of 3 years of continuous etanercept (ETN) treatment was assessed. In a previously reported ESTHER trial, patients with axSpA were randomized to treatment with ETN (n = 40) versus sulfasalazine (SSZ; ...
Takamura Yoshihiro Y Ophthalmology, University of Fukui, 23-3 Matsuoka, Eiheiji-cho, Yoshida-gun, Fukui, 910-1193, Japan - - 2014
Purpose:This study aimed to investigate whether targeted retinal photocoagulation (TRP) for non-perfusion areas (NPAs) could have preventive effect for the recurrence of diabetic macular edema (DME) after intravitreal injection of bevacizumab (IVB). Methods:Eyes in the IVB group received 1.25 mg IVB and eyes in the IVB+TRP group received 1.25 mg ...
Metelmann Hans-Robert HR Department of Oral and Maxillofacial Surgery/Plastic Surgery, Medical School, Greifswald University, Greifswald, - - 2014
The acceleration of wound healing is a major surgical concern. A triterpene extract from birch bark (Betulae cortex) experimentally enhances keratinocyte differentiation in vitro and accelerates wound healing ex vivo. We conducted an open, blind-evaluated, controlled, prospective, randomized (1:1) phase II clinical trial in patients requiring split-thickness skin graft transplantation ...
Collet Jean-Philippe JP ACTION Study Group, Institut de Cardiologie Hôpital Pitié-Salpêtrière (APHP), Université Paris 6, INSERM, Paris, - - 2014
Optimum duration of dual antiplatelet treatment (DAPT) after coronary stenting remains uncertain, with an unknown efficacy to safety ratio of extended treatment leading to discrepancies between international guidelines and clinical practice. We assessed whether DAPT continuation beyond 1 year after coronary stenting is beneficial. This analysis was a planned extension ...
Kang Ho Min HM Department of Otorhinolaryngology, School of Medicine, Kyung Hee University, Seoul, - - 2014
The effectiveness of antiviral agents for the treatment of Bell's palsy is uncertain. We evaluated whether a steroid with an antiviral agent (S+A group) provided better recovery outcomes than a steroid alone (S group) in patients with Bell's palsy. A total of 1342 patients diagnosed with Bell's palsy who visited ...
Azevedo C C Medicina de Produção Leiteira Veterinária Lda. (MPLVET), Tocha, - - 2014
The main aims of the present study were to compare the pregnancy rate (PR), regular returns-to-estrus, and calving interval of a CO-Synch + controlled internal drug release (CIDR) device, commonly used to synchronize ovulations in beef cows, with the classical Ovsynch protocol in high-producing dairy cows. Holstein-Friesian cows (n = 128) from six commercial ...
Pro Michael J MJ Department of Glaucoma, Wills Eye Hospital , Philadelphia, PA , USA - - 2014
ABSTRACT Purpose: The current standard adjunctive agent used in primary trabeculectomy is mitomycin C (MMC), but it is associated with well known complications. The objective of this study is to test the feasibility of the anti-vascular endothelial growth factor (anti-VEGF) agent ranibizumab for adjunctive use instead of MMC (0.4 mg/ml). Materials ...
Fouka Evangelia E Department of Pneumonology, General Hospital G.Papanikolaou, Aristotle University of Thessaloniki, Exohi, 57010, Thessaloniki, Greece, - - 2014
Th17 cells play a crucial role in neutrophilic inflammation and tissue injury in non-cystic fibrosis (non-CF) bronchiectasis. Clarithromycin demonstrates anti-inflammatory and immunomodulatory properties but the effect of long-term clarithromycin prophylaxis on the Th17 response in non-CF bronchiectasis is still unexplored. Th17 response was studied in 22 patients with stable non-CF ...
Taal Walter W Department of Neuro-oncology, Erasmus MC Cancer Institute, Rotterdam, - - 2014
Treatment options for recurrent glioblastoma are scarce, with second-line chemotherapy showing only modest activity against the tumour. Despite the absence of well controlled trials, bevacizumab is widely used in the treatment of recurrent glioblastoma. Nonetheless, whether the high response rates reported after treatment with this drug translate into an overall ...
Selleslag Dominik D AZ Sint-Jan, Brugge-Oostende, - - 2014
This post hoc analysis evaluated romiplostim self-administration (SA group) versus romiplostim administration by a healthcare provider in a clinical setting (HCP group) in patients with chronic immune thrombocytopenia (ITP). Outcomes from 3 ITP trials allowing self-administration in patients achieving a stable romiplostim dose for ≥3 consecutive weeks were compared. Evaluations ...
Markantoni Vasiliki V Department of Dermatology and Venereology, Hospital "Andreas Sygros", Athens, - - 2014
Dyshidrotic hand eczema is a common condition, which can be resistant to various treatments. Although a number of etiologic factors are involved in the pathogenesis of dyshidrotic eczema, hyperhidrosis is assumed to play a significant role. Oxybutynin is an alternative treatment for hyperhidrosis. We present the cases of two patients ...
Puzzilli Fabrizio F Department of Neurosurgery, "Sandro Pertini" Hospital, Rome, - - 2014
Interspinous distraction devices provide an effective treatment for patients suffering from lumbar spinal stenosis and/or degenerative disk disease. The aim of this multicenter study was the prospective evaluation of patients treated for symptomatic lumbar spinal stenosis with interspinous process decompression (IPD) implants compared with a population of patients managed with ...
Traversi Claudio C Department of Medicine, Surgery and Neuroscience, University of Siena, Viale Bracci 1, 53100, Siena, - - 2014
To evaluate the long-term efficacy of bevacizumab in the treatment of choroidal neovascularization (CNV) secondary to pathological myopia. In this retrospective single-center non-comparative study the medical records of 29 eyes from 29 patients with naïve CNV secondary to high myopia and at least 42 months of follow up were reviewed. All ...
Naini Farhad B FB *Department of Orthodontics, Kingston and St George's Hospital and Medical School, - - 2014
Summary BACKGROUND : The nasolabial angle, particularly its lower component, i.e. the upper lip inclination (ULI), is an important keystone in treatment planning. Normative data for this parameter are not available. A quantitative evaluation of the aesthetic impact of ULI on perceived attractiveness and threshold values of desire for treatment ...
Al-Khateeb Susan N SN Department of Preventive Dentistry, Faculty of Dentistry, Jordan University of Science and Technology, Irbid, Jordan - - 2014
Summary OBJECTIVES : The aim of this study was to determine the occlusal bite force (OBF) changes, at the incisal and molar regions, after orthodontic treatment with functional appliance therapy in preadolescent subjects. OBF was measured for patients (17 females and 16 males) before and after the treatment with Andresen ...
Hurford Robert R Stroke and Vascular Research Centre, Institute of Cardiovascular Sciences, University of Manchester, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Manchester, UK Comprehensive Stroke Centre, Greater Manchester Neurosciences Centre, Salford Royal NHS Foundation Trust, Manchester, - - 2014
Orolingual angio-oedema is a recognised complication of tissue plasminogen activator (tPA) for ischaemic stroke. We investigated its incidence, clinical characteristics and relationship with other factors in patients receiving tPA at a UK centre. 530 consecutive patients (median age 70 years) receiving tPA treatment for confirmed ischaemic stroke were included. Cases were ...
Ahmad Hesham M HM Department of Dermatology and Venereology, Faculty of Medicine, Minia University, Minia, - - 2014
Many medications are available for treatment of pediculosis capitis including ivermectin. Our aim is to compare the efficacy and safety of topical versus oral ivermectin in treatment of pediculosis capitis. Sixty-two patients with proved head lice infestation were included and divided into group I (31 patients; received single topical application ...
Karsai S S Clinic for Dermatology, Darmstadt, Germany; University Hospital Greifswald, Dept. of Dermatology, Greifswald, - - 2014
Pulsed dye laser (PDL) treatments have been suggested to be a safe and effective therapeutic approach for treating basal cell carcinomas. Robust supporting evidence is, however, lacking due to inconsistent design of available studies. To evaluate the PDL's efficacy and safety in treating superficial basal cell carcinoma (sBCC) at low-risk ...
Franeková Janka - - 2014
Abstract Background: Galectin-3 is an emerging biomarker of heart failure and of myocardial fibrosis risk. Monitoring of galectin-3 is essential during treatment with galectin-3 inhibitors. The aim of our study was to assess long-term biological variability in a specific group of unhealthy subjects. Methods: The biological variability of galectin-3 was ...
Zhao Jialiang J Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, 1, Shuai Fu Yuan, Dongcheng District, Beijing, 100730, China, - - 2014
To evaluate the efficacy and safety of monthly ranibizumab 0.5 mg in Chinese patients with subfoveal choroidal neovascularization (CNV) secondary to neovascular age-related macular degeneration (nAMD). A 12-month open-label single-arm multicenter phase III study that included treatment-naïve (study eye) patients with primary/recurrent subfoveal CNV secondary to AMD. Patients (N = 114) aged ≥50 years ...
Richardson Monica L ML Stanford University School of Medicine, Stanford, - - 2014
To determine whether conservative or surgical therapy is more cost effective for the initial treatment of stress urinary incontinence. We created a decision tree model to compare costs and cost effectiveness of three strategies for the initial treatment of SUI: a) continence pessary b) pelvic floor muscle therapy c) mid-urethral ...
Murina Filippo F Outpatient Department of Vulvar Disease, V. Buzzi Hospital-ICP-University of Milan, Milan, - - 2014
To compare the efficacy of the short-term application of clobetasol propionate 0.05% (CLB) and mometasone furoate 0.05% (MMF) in the treatment of vulvar lichen sclerosus (VLS). This study was a retrospective review of 96 women who were diagnosed with lichen sclerosus with a follow-up of at least 1 year. Of ...
Yamamoto Erica E Pediatric Gastroenterology Division, Escola Paulista de Medicina, Universidade Federal de São - - 2014
AIM:: to estimate the rate of clinical and endoscopic relapse after initial treatment of erosive peptic esophagitis in children and adolescents. 24 patients (2.1 to 16.4 year-old, mean ± SD: 9.9 ± 3.1; M:F 3) with healed endoscopic erosive esophagitis and without GERD-predisposing conditions were followed up for 4 to 32.9 months (mean 20.8 yrs ± 10.6). ...
Tremaine Anne Marie AM *Department of Dermatology and Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; †Goldman, Butterwick, Fitzpatrick, Groff & Fabi: Cosmetic Laser Dermatology, San Diego, - - 2014
Despite being the gold standard for lower extremity reticular vein treatment, few studies have yet evaluated foam sclerotherapy for hand veins. This retrospective study evaluates the safety and efficacy of foam sclerotherapy for reticular veins of the dorsal hands. A telephone-based questionnaire was used for patient self-assessment of overall improvement, ...
Yun Woo Jin WJ *All the authors are affiliated with the Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, - - 2014
Recently, intense pulsed light (IPL) and low-fluence Q-switched neodymium-doped yttrium aluminum (LF-QS-Nd:YAG) laser have been successfully used to treat melasma. To evaluate the effectiveness and safety of combined novel fractionated IPL (IPL-F) with LF-QS-Nd:YAG laser in patients with melasma. Twelve patients underwent 6 treatment sessions of concomitant IPL-F and LF-QS-Nd:YAG ...
Işik Selda S Department of Dermatology, Faculty of Medicine, Çanakkale Onsekiz Mart University, Çanakkale, - - 2014
Anogenital warts are caused by human papillomavirus (HPV), over 30 types of which are infectious for the anogenital tract. Without treatment, warts may regress spontaneously, remain unchanged, or increase in number and size. This study compared the efficacy of a topical 5% potassium hydroxide (KOH) solution with that of a ...
Chandrashekar Byalakere Shivanna BS Rajiv Gandhi University of Health Sciences, Karnataka, India; Diplomate of National Board, New Delhi, - - 2014
It is reported that patients on oral isotretinoin have greater risk of developing scars and delayed wound healing with invasive procedures. It is recommended that these procedures be resumed 6-12 months after the last dose of oral isotretinoin. To assess and compare the safety and look for delayed wound healing, during ...
Haas Alex Nogueira AN Periodontology Department, School of Dentistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, - - 2014
Properly performed daily mechanical biofilm control is the most important prevention strategy for periodontal diseases. However, proper mechanical biofilm control is not performed effectively by the majority of the population, mainly due to lack of motivation and of manual dexterity. Local biofilm retention factors may aggravate home oral hygiene quality. ...
Zhang Yifei Y Rui-jin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, - - 2014
We recently demonstrated a beneficial effect of metformin compared with glipizide in type 2 diabetic patients regarding cardiovascular outcomes for 3-year treatment in the SPREAD-DIMCAD study. However, the potential mechanism for the clinical effects remains unclear. Here, we performed a comprehensive lipidomics study to evaluate the different lipid metabolites in ...
Troeltzsch Markus - - 2014
Objective: To investigate the efficacy of conservative dental treatment (occlusal splint and pharmacologic therapy) and invasive therapy (prosthetic restorations) in the treatment of tension-type headache (TTH). Method and Materials: The study sample was composed of 70 patients who presented with symptomatic TTH and were assigned to three treatment groups according ...
Sanchis Jose María - - 2014
Objective: A study was designed to measure of the incidence of bisphosphonate-related osteonecrosis of the jaws (BRONJ) following tooth extraction in patients receiving or who have received intravenous bisphosphonates (Zometa, zoledronic acid). Method and Materials: A prospective cohort study was made of 36 patients subjected to 62 tooth extractions. All ...
Dungan Kathleen M KM The Ohio State University, Columbus, OH, USA. Electronic address: - - 2014
Dulaglutide and liraglutide, both glucagon-like peptide-1 (GLP-1) receptor agonists, improve glycaemic control and reduce weight in patients with type 2 diabetes. In a head-to-head trial, we compared the safety and efficacy of once-weekly dulaglutide with that of once-daily liraglutide in metformin-treated patients with uncontrolled type 2 diabetes. We did a ...
Tagalakis Vicky V Centre for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada. Electronic address: - - 2014
Few studies have assessed treatment patterns of acute venous thromboembolism (VTE) in a real-world population. We aimed to describe anticoagulant treatment patterns for acute VTE using healthcare databases of Québec, Canada. We used linked healthcare databases of the province of Québec, Canada to identify all incident cases of deep vein ...
Sadiq Saghir Ahmed SA Manchester Royal Eye Hospital, Oculoplastics, Orbital and Lacrimal - - 2014
Abstract Background: Botulinum toxin A (BTXA) injection to the levator palpebrae superioris muscle to induce a protective ptosis can adversely cause reduced upgaze due to diffusion of BTXA to the superior rectus muscle. Purpose: To compare the incidence of reduced upgaze in trascutaneous versus transconjunctival administration of BTXA to induce ...
Kinon Bruce J BJ Eli Lilly and Company, Indianapolis, IN, - - 2014
The risk of persistent tardive dyskinesia (TD) was compared in patients with acute psychosis or agitation aged 55 years or older who were treated with olanzapine (OLZ) or conventional antipsychotic (CNV) drug therapy. Patients without TD were randomized to treatment with OLZ (2.5-20 mg/d; n = 150) or CNV (dosed ...
Shin Joo Young JY *Department of Ophthalmology, Seoul National University Hospital, Seoul, South Korea; and †Sensory Organs Institute, Medical Research Center, Seoul National University, Seoul, South - - 2014
To evaluate the visual outcome of optical coherence tomography-based ranibizumab monotherapy in Korean patients with retinal angiomatous proliferation and identify prognostic factors of visual outcome. A prospective single-arm clinical study of 31 retinal angiomatous proliferation patients who underwent 3 consecutive monthly intravitreal ranibizumab injections was conducted. Additional treatment was given ...
Chiu Chun-Chieh CC Department of Physical Medicine and Rehabilitation, Wan Fang Hospital, Taipei Medical University, - - 2014
To determine the probability of spontaneous disc regression among each type of lumbar herniated disc, using a systematic review. Medline, Cochrane Library, CINAHL, and Web of Science were searched using key words for relevant original articles published before March 2014. Articles were limited to those published in English and human ...
Ozcan Altan A AA *Faculty of Medicine, Department of Ophthalmology, Çukurova University, Adana, Turkey; and †Department of Ophthalmology, Adana Numune Training and Research Hospital, Adana, - - 2014
To report our experience in the treatment of intraepithelial neoplasia of the conjunctiva using topical bevacizumab. Ten eyes of 10 patients with conjunctival neoplasia received 25 mg/mL bevacizumab topically. Changes in the lesions were documented weekly using digital photography. After topical treatment, excisional biopsy was performed. The mean age of ...
Caúla André Luis AL Department of Periodontology, School of Dentistry, Rio de Janeiro State University, Rio de Janeiro, - - 2014
To determine the influence of non-surgical mechanical periodontal treatment on inflammatory markers related to risk for cardiovascular disease. A total of 64 patients with severe chronic periodontitis was randomly subjected to immediately periodontal treatment (test group, n = 32) or delayed periodontal treatment, without treatment during the study period (control ...
John Anitha S AS Division of Cardiology, Children's National Medical Center, George Washington University School of Medicine, Washington, DC; Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota. Electronic address: - - 2014
Patients with protein-losing enteropathy (PLE) following the Fontan operation have a reported 50% mortality at 5 years after diagnosis. The aim of this study was to review outcomes in patients with PLE following the Fontan operation. From 1992 to 2010, 42 patients (55% male) with PLE following the Fontan operation ...
Wiedel Anna-Paulina AP a Research Fellow, Department of Oral and Maxillofacial Surgery, Skane University Hospital, Malmö, - - 2014
Abstract Objective: To compare and evaluate the stability of correction of anterior crossbite in the mixed dentition by fixed or removable appliance therapy. Material and Methods: The subjects were 64 consecutive patients who met the following inclusion criteria: early to late mixed dentition, anterior crossbite affecting one or more incisors, ...
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