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Results 251 - 300 of 9476
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Anchala Praveen R - - 2014
Spinal metastatic lesions are a common occurrence among oncology patients and contribute to significant morbidity. Treatment options have been limited in their effectiveness and scope to this point. This study aims to report the safety and efficacy of radiofrequency ablation (RFA) of malignant spinal lesions using a novel RFA bipolar ...
Admani Shehla S Division of Pediatric and Adolescent Dermatology, Rady Children's Hospital-San Diego and University of California at San Diego School of Medicine, San Diego, - - 2014
Infantile hemangiomas are benign vascular tumors seen in 4.5 percent of neonates and infants. While most infantile hemangiomas can be managed with active nonintervention, a subset of patients will require more aggressive management. Here the authors review the use of beta-blockers in the treatment of infantile hemangiomas, including oral, topical, ...
Park Sang Woo SW Department of Radiology, Konkuk University Hospital, Konkuk University School of Medicine, Seoul 143-729, - - 2014
To compare the efficacy and adverse effects of endovenous foam sclerotherapy (EFS) and liquid sclerotherapy (ELS) using a microcatheter for the treatment of varicose tributaries. From December 2007 to January 2009, patients with venous reflux in the saphenous vein were enrolled. The foam or liquid sclerosant was injected through a ...
Noaiseh Ghaith G Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. - - 2014
There are currently no head-to-head comparisons of sialagogues for Primary Sjögren's syndrome (pSS). We compared the tolerability and side effect profile of pilocarpine and cevimeline in patients with pSS and determined clinical, laboratory and pathological variables associated with therapeutic failure. We retrospectively reviewed the use of pilocarpine and cevimeline in ...
Vidal G G Neurology, Radiology and Neurosurgery, Ochsner Clinic Foundation, New Orleans, LA, - - 2014
Most patients with large vessel occlusion (LVO) present with high NIHSS, and it has been shown that initial NIHSS is a predictor of outcomes in patient with acute ischemic stroke. The usefulness of neuroendovascular reperfusion has been a controversial topic. The aim of this study was to compare the outcomes ...
Chalouhi N N Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, PA, - - 2014
Stenting techniques such as stent-assisted coiling and flow diversion are increasingly used for treatment of intracranial aneurysms. In previous reports, patients were pretreated were aspirin and clopidogrel prior to the intervention for prevention of thromboembolic complications. Prior studies also often rely on aspirin response and P2Y assessment, which often delays ...
Park M M Neurological Surgery, Barrow Neurological Institute, Phoenix, AZ, - - 2014
The Pipeline Embolization Device (PED, eV3 Neurovascular, Irvine, California) has increased the ability of the neurointerventionalist to treat progressively more difficult cerebrovascular pathology. We sought to determine the efficacy of the PED in the treatment of the most recalcitrant of aneurysms, those aneurysms recurring after previous treatments. We retrospectively queried ...
Turk A A 3rd NeuroEndovascular Surgery, Medical University of South Carolina, Charleston, SC, - - 2014
The use of mechanical thrombectomy for treatment of acute ischemic stroke has significantly advanced over the last 5 years. Little data is available analysing the cost relative to the clinical and angiographic outcomes. The aim of this study is to analyze the cost and efficacy of current stroke therapy. A ...
Pierot L L Radiology, Hôpital Maison-Blanche, Reims, - - 2014
To evaluate the feasibility, safety, and efficacy of endovascular treatment with flow diverters (FD) in patients with recanalised and multitreated aneurysms, in a retrospective, multicenter, single-arm study. The study included 29 patients with 29 recanalised aneurysms who were treated by FDs (Silk or Pipeline device). Per and post procedural complications ...
Alexander M M Radiology, Santa Clara Valley Medical Center, San Jose, CA, - - 2014
Endovascular treatment of intracranial atherosclerotic disease is controversial, and optimal treatment remains unclear. Acute ischemic stroke (AIS) due to thrombosis of an in situ stenosis has undergone little investigation. Infarction from such disease in the posterior circulation causes pronounced morbidity. We reviewed outcomes of patients undergoing endovascular treatment of AIS ...
Robert T T Interventional Neuroradiology, Rothschild Foundation Hospital, Paris, - - 2014
Arteriovenous malformations (AVM) of the corpus callosum were rare lesions, accounting for 9-11% of brain AVMs. Microsurgical resection of such lesions remained difficult regarding deep location and possible neuropsychological disasters of extended callosal resection. The introduction of endovascular and radiation therapies fundamentally changed the outcome of these lesions. Since 1995, ...
Alexander M M Radiology, University of Washington, Seattle, CA, - - 2014
Intracranial atherosclerotic disease (ICAD) is often stratified by degree of stenosis. Additional features such as patient demographics and symptom characteristics also affect lesion behavior and response to treatment. This study compares stratification by degree of narrowing to these additional features. Retrospective analysis was performed on patients at 4 hospitals with ...
Chowdhary A A Director of Neurosurgery and Neuro-Interventional Surgery, Overlake Hospital, Bellevue, WA, - - 2014
Radiation exposure during an angiographic procedure may present a significant health risk to patients. The goal of this multicenter case study (CARE) is to compare such exposure in patients treated with the novel Penumbra Coil 400™ System (PC 400) vs. conventional coils. The PC 400 coils are a new generation ...
Lee Min Seok MS Sophie-Marceau Women's Clinic, Daegu, South - - 2014
Vaginal relaxation syndrome (VRS) is both a physical and psychological problem for women and often their partners. Recently the 2940 nm Er:YAG laser has attracted attention for VRS treatment. The current study evaluated the clinical efficacy of this nonsurgical laser procedure. Thirty postpartum females with VRS or vaginal atrophy, ages ...
Walker Paul C - - 2014
This study was designed to evaluate the long-term results using the technique of canal wall reconstruction (CWR) tympanomastoidectomy with mastoid obliteration in the treatment of chronic otitis media with cholesteatoma. Institutional review board-approved retrospective case review. Tertiary referral center. Retrospective review was performed on consecutive patients undergoing CWR tympanomastoidectomy with ...
Min Jang Hwan JH Department of Plastic and Reconstructive Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, - - 2014
For patients with full thickness skin defects, autologous Split-thickness skin grafts (STSG) are generally regarded as the mainstay of treatment. However, skin grafts have some limitations, including undesirable outcomes resulting from scars, poor elasticity, and limitations in joint movement due to contractures. In this study, we present outcomes of Matriderm ...
Joyce Kenneth Michael KM Department of Plastic and Reconstructive Surgery, Galway University Hospital, Galway, - - 2014
Proximal interphalangeal joint (PIPJ) dislocations represent a significant proportion of hand clinic visits and typically require frequent follow-ups for clinical assessment, orthotic adjustments, and physiotherapy. There are a large number of treatment options available for PIPJ dislocations, yet no prospective or controlled studies have been carried out, largely due to ...
Cunningham Daniel J - - 2014
Background : We hypothesized that needling of a pedal wart creates local inflammation and a subsequent cell-mediated immune response (CMIR) against human papillomavirus. The primary objective of this study was to investigate whether needling to induce a CMIR against human papillomavirus is an effective treatment for pedal warts compared with ...
Fernández Maria Luz González - - 2014
Background : We sought to assess the biomechanical characteristics of the feet of patients with Charcot neuro-osteoarthropathy and to determine reulceration rates before and after personalized conservative orthotic treatment. Methods : A longitudinal prospective study was performed in 35 patients with Charcot's foot. Although some patients had a history of ...
van den Bos R R RR Department of Dermatology, Erasmus MC University Medical Centre, - - 2014
The aim was to compare endovenous laser ablation (EVLA) and endovenous steam ablation (EVSA) for great saphenous varicose veins in a non-inferiority study. Patients with primary great saphenous vein reflux were randomized to EVLA (940 nm) or EVSA (SVS™). Primary outcomes were treatment success (vein obliteration) at 52 weeks, and Venous Clinical ...
Sunseri Whitney W 1Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania; 2Department of Pediatrics, Connecticut Children's Medical Center, Hartford, Connecticut; 3Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada; 4Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, ON, Canada; 5Department of Pediatrics, I.W.K. Health Center, Halifax, NS, Canada; 6Pediatric Gastroenterology, Goryeb Children's Hospital, Morristown, New Jersey; 7Department of Pediatrics, Nationwide Children's Hospital, Columbus, Ohio; 8Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; 9Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin; 10Section of Gastroenterology/Hepatology/Nutrition, Riley Hospital for Children, Indianapolis, Indiana; 11Department of Gastroenterology, Dayton Children's, Dayton, Ohio; 12Division of Pediatric Gastroenterology, Nutrition and Liver Diseases, Hasbro Children's Hospital, Providence, Rhode Island; 13Department of Pediatrics, Russell Children's Hospital, Birmingham, Alabama; 14Division of Pediatric Gastroenterology and Nutrition, Johns Hopkins University School of Medicine, Baltimore, Maryland; 15Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Medical Center, Cincinnati, Ohio; 16Department of Pediatrics, University of North Carolina, Chapel Hill, North Carolina; and 17Department of Pediatrics, Cohen Children's Medical Center, New Hyde Park, New - - 2014
Methotrexate (MTX) use as an alternative to thiopurines in the treatment of Crohn's disease (CD) in children is increasing. This study was undertaken to assess safety and efficacy of MTX in children with CD. Patients treated with MTX with a minimum of 1-year follow-up were identified in the Pediatric IBD ...
Chavoustie Steven E SE 1Segal Institute for Clinical Research, North Miami, FL; 2TMC Life Research, Inc., Houston, TX; 3Atlanta North Gynecology, P.C., Roswell, GA; 4Downtown Women's Health Care, Denver, CO; 5Prosoft Clinical, Wayne, PA; 6Department of Obstetrics, Gynecology and Reproductive Sciences and the Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA; and 7Department of Obstetrics and Gynecology, Drexel University, Philadelphia, - - 2014
Metronidazole vaginal gel (MVG) 0.75% is a US Food and Drug Administration-approved, 5-day treatment for bacterial vaginosis (BV). This study tested the hypothesis that a shorter treatment course at a higher dose (MVG 1.3%) would yield similar efficacy to 5 days of MVG 0.75%. This phase 2, multicenter, randomized, controlled, ...
DeMartini Julie K JK 1Korey Stringer Institute, University of Connecticut, Storrs, CT 2Falmouth Hospital, Falmouth, - - 2014
Investigate the effectiveness (speed of cooling and survival rates) of cold water immersion (CWI) in the treatment of exertional heat stroke (EHS) patients. Secondly, to compare cooling rates based on gender, age, and initial rectal temperature (Tr). Eighteen years of finish line medical tent patient records were obtained from the ...
Judd William R WR Saint Joseph Hospital, Lexington, KY, USA - - 2014
Studies evaluating the clinical effectiveness of sepsis screening tools and methods to improve the time from diagnosis to antibiotic administration are needed to improve sepsis-related outcomes. To evaluate the clinical and economic impact of a sepsis quality improvement initiative to improve early recognition and treatment of sepsis. A retrospective observational ...
Grzechocinska Barbara B 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, - - 2014
Uterine fibroids are the most common benign tumors in women of reproductive age. Evidence suggest that ovarian steroid hormones, in particular, progesterone play a major role in promoting leiomyoma development and growth. For the last years there was an extensive research on selective progesterone receptor modulators and their use in ...
Bechtler Matthias M Medizinische Klinik C, Klinikum Ludwigshafen, Ludwigshafen, - - 2014
Endoscopic bougienage seems to be the most effective therapy for dysphagia in esophageal intramural pseudodiverticulosis (EIPD), but nothing is known about the long-term success of this treatment option. This report presents long-term results for 21 of 22 patients with EIPD who were treated with bougienage. A total of 103 sessions ...
Martinez-Escala M Estela ME Department of Dermatology, Hospital del Mar, Parc de Salut Mar, Institut Municipal d'Investigació Mèdica, Barcelona, - - 2014
Cold contact urticaria is the second most common subtype of physical urticaria. Cold stimulation standardized tests are mandatory to confirm the diagnosis. The aim of this study is to define the utility of determining thresholds (critical time and temperature) in assessment of the clinical course of typical acquired cold contact ...
Robard L L Service ORL, CHU Côte-de-Nacre, avenue de la Côte-de-Nacre, 14033 Caen cedex 9, France. Electronic address: - - 2014
Osteoradionecrosis (ORN) is a severe, generally irreversible complication of radiotherapy due to failure of healing. The pentoxifylline-tocopherol combination decreases the superficial fibrosis induced by radiotherapy. Potentiation by Clodronate (PENTOCLO) appears to be effective in ORN of the mandible. The objectives of this study were to evaluate the efficacy and safety ...
Bright Ralph - - 2014
Chronic migraines and tension-type headaches are debilitating diseases affecting 1.4 to 2.2% of the population with both quality of life and economic implications. To date, the pain associated with migraine and tension-type headaches has been controlled with a range of medications, with varying levels of success. In addition, the side-effect ...
Osborn David James DJ Department of Urology, Vanderbilt University Medical Center, Nashville, - - 2014
The purpose of this study was to find the rate of urinary retention in clinical practice after treatment with onabotulinumtoxinA (BTN/A) for refractory overactive bladder (OAB) symptoms and determine factors that predict this outcome. This is a retrospective study of BTN/A for treatment of non-neurogenic, refractory OAB symptoms. Patients were ...
An A-Yue AY Anorectal Department, China-Japan Friendship Hospital, Beijing, 100029, China, - - 2014
To compare the effect of An's Shaobei Injection () with Xiaozhiling Injection () in patients with internal hemorrhoids of grade I-III. This cohort study included 1,520 internal hemorrhoids patients with grade I-III who were scheduled for liquid injection treatment from July 2003 to July 2009. The cohort included patients who ...
Küçükerdönmez Cem C * These authors contributed equally to the - - 2014
To compare the outcomes after switching between bevacizumab and ranibizumab therapy due to poor treatment effect in neovascular age-related macular degeneration (AMD). This is a retrospective review of patients with neovascular AMD with first treatment using intravitreal bevacizumab (group 1) or ranibizumab (group 2) who switched to the other drug ...
Tracey Robert W RW Department of Orthopaedic Surgery, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue, Building 19, Bethesda, MD 20889, - - 2014
Several studies have established the short-term safety and efficacy of cervical disc arthroplasty (CDA) as compared to anterior cervical discectomy and fusion (ACDF). However, few single-center comparative trials have been performed, and current studies do not contain large numbers of patients. We retrospectively reviewed all patients from a single military ...
Palazzuoli Alberto - - 2014
Intravenous loop diuretics are a cornerstone of therapy in acutely decompensated heart failure (ADHF). We sought to determine if there are any differences in clinical outcomes between intravenous bolus and continuous infusion of loop diuretics. Subjects with ADHF within 12 hours of hospital admission were randomly assigned to continuous infusion ...
Deeks Emma D ED Adis, Level 1, The Warehouse Way, Northcote 0627; Private Bag 65901, Mairangi Bay 0754, Auckland, New Zealand, - - 2014
Ranibizumab (Lucentis(®)) is the first inhibitor of vascular endothelial growth factor (VEGF)-A licensed for the treatment of visual impairment due to choroidal neovascularization (CNV) secondary to pathologic myopia (i.e. myopic CNV). The drug inhibits biologically active isoforms of VEGF-A and is administered via intravitreal injection, with the number of treatments ...
Hwang Sena S Division of Endocrinology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, 120-752, Republic of - - 2014
There are scarce reports regarding a functional prognostic value of thyroid-stimulating autoantibody (TSAb) levels using a thyroid-stimulating hormone receptor chimera (Mc4) in Graves' disease (GD) in iodine sufficient area. The aim of this study was to investigate whether Mc4-TSAb can predict GD remission/relapse after antithyroid drug (ATD) treatment and to ...
Ghobrial George M GM -Department of Neurological Surgery, Thomas Jefferson University Hospital, 909 Walnut St., 3(rd) floor, Philadelphia, PA - - 2014
To identify surgical practice patterns in the literature for non-pediatric syringomyelia by systematic review and to determine: (1) What is the best clinical practice of CSF diversion that will maximize clinical improvement and/or the lowest recurrence rate? (2) Does arachnolysis, rather than CSF diversion, lead to prolonged times to clinical ...
Alushi Brunilda B aDivision of Cardiology, University of Turin, San Giovanni Battista Hospital, Turin, Italy bDivision of Cardiology, Maria Vittoria Hospital, Turin, Italy cDivision of Cardiology, Cardinal Massaia Hospital, Asti, Italy dDepartment of Neuroscience, San Giovanni Battista Hospital, Turin, - - 2014
There is still controversy regarding the benefit of percutaneous closure of patent foramen ovale (PFO) among patients with cryptogenic stroke. Here we aimed to evaluate the factors associated with treatment choice and predictors of adverse events in patients with cryptogenic stroke or transient ischemic attack (TIA) and PFO. Of 418 ...
van Hessem Lotte L Departments of aOrthopaedic Surgery bResearch, Sint Maartenskliniek, Nijmegen cDepartment of Orthopaedic Surgery, VU University Medical Centre, Amsterdam, The - - 2014
Nonoperative management of juvenile idiopathic scoliosis (JIS) has been reported to be less effective than that of infantile idiopathic scoliosis. The goal of this study was to analyse the results of casting and/or bracing in JIS. Clinical data from seven patients with JIS, treated with casting followed by bracing (n=3) ...
Triantos Christos C Christos Triantos, Maria Kalafateli, Department of Gastroenterology, University Hospital of Patras, 26500 Patras, - - 2014
Variceal bleeding is a life threatening situation with mortality rates of at least 20%. Prophylactic treatment with non-selective beta blockers (NSBBs) is recommended for patients with small varices that have not bled but with increased risk for bleeding. The recommended treatment strategies on primary prevention of variceal bleeding in patients ...
Akin Melih M Pediatric Surgery Department, Sisli Etfal Education and Training Hospital, Istanbul, - - 2014
We aimed to compare the success rates of the double hydrodistention implantation technique (HIT) and the HIT with a polyacrylate/polyalcohol copolymer (PPC) for the treatment of primary vesicoureteral reflux (VUR) with a new nonbiodegradable tissue-augmenting substance (Vantris, Promedon, Cordoba, Argentina). Between January 2011 and December 2012, fifty-two children who underwent ...
Caminal M M Divisió de Teràpies Avançades/XCELIA, Banc de Sang i Teixits, Edifici Dr. Frederic Duran i Jordà, Passeig Taulat, 116, 08005, Barcelona, - - 2014
Clinical translation of emerging technologies aiming at cartilage resurfacing is hindered by neither the appropriate scaffold design nor the optimal cell source having been defined. Here, critical-sized, chondral-only focal defects were created in sheep and treated with clinical-grade, co-polymeric poly-lactide:polyglycolic acid scaffolds either alone or seeded with 3.3 × 10(6) ± 0.4 × 10(6) autologous bone ...
Yamamoto S S Division of Vascular Surgery, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, - - 2014
To evaluate the outcomes of surgical revascularization for critical limb ischemia in patients with end-stage renal disease (ESRD). From 2004 to 2010, 184 patients with 213 critically ischaemic limbs caused by arteriosclerosis were admitted to The University of Tokyo Hospital. The outcomes of primarily surgical revascularization-based treatments were retrospectively compared ...
Chen Leonard N - - 2014
Purpose: Urinary incontinence (UI) following prostate radiotherapy is a rare toxicity that adversely affects a patient's quality of life. This study sought to evaluate the incidence of UI following stereotactic body radiation therapy (SBRT) for prostate cancer. Between February, 2008 and October, 2010, 204 men with clinically localized prostate cancer ...
McKenna Gerald G Cork University Dental School and Hospital, University College Cork, Ireland. Electronic address: - - 2014
This study aimed to compare two different tooth replacement strategies for partially dentate older patients; namely functionally orientated treatment according to the principles of the shortened dental arch (SDA) and conventional treatment using removable partial dentures (RPDs) using a randomised controlled clinical trial. The primary outcome measure for this study ...
Yap Desmond Y H DY Division of Nephrology, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong - - 2014
Although nucleotide/side analogues improve the clinical outcome of hepatitis B surface antigen positive (HBsAg+) kidney transplant recipients (KTR), a significant proportion of subjects have developed resistance to Lamivudine (LAM). We retrospectively analyzed the efficacy and tolerability of entecavir (ETV) in HBsAg+ KTR at Queen Mary Hospital during 2005-2013. 21 patients ...
Gawriołek Krzysztof K Prosthetic Department, Oral Rehabilitation Clinic, Poznan University of Medical Sciences, Poznan, Poland. Electronic address: - - 2014
The aim of this study was to analyze the efficacy of Myorelaxation Therapy in temporomandibular disorders on the basis of mandibular movement measurements, reported functional impairment and clinical findings. To ascertain the mandibular movements 78 women were investigated. The first group consisted of 32 consecutive patients (23.3±4.8 years) suffering from ...
Kibleur Yves Y Lucane Pharma, 172 rue de Charonne, 75011, Paris, France, - - 2014
The aim of this study was to describe a nationwide system for pre-marketing follow-up (cohort temporary utilization authorization [ATU] protocol; i.e., 'therapeutic utilization') of a new taste-masked formulation of sodium phenylbutyrate (NaPB) granules (Pheburane(®)) in France and to analyze safety and efficacy in this treated cohort of patients with urea ...
Ileri Zehra Z a Assistant Professor, Department of Orthodontics, Faculty of Dentistry, Selçuk University, Konya, - - 2014
Abstract Objective: To investigate the short-term effects of the asymmetric rapid maxillary (ARME) appliance on the vertical, sagittal, and transverse planes in patients with true unilateral posterior crossbite. Materials and Methods: Subjects were divided into two groups. The treatment group was comprised of 21 patients with unilateral posterior crossbite (mean ...
Kim Jung Hoon JH Department of Radiology, Institute of Radiation Medicine, Seoul National University College of Medicine, 101 Daehangno, Jongno-gu, Seoul, 110-744, Republic of Korea, - - 2014
To assess therapeutic efficacy of gemcitabine and HIFU for a mouse model of pancreatic cancer, and the role of DCE-US for predicting early treatment response compared with pathology. In 48 PANC-1- nude mice (G1, HIFU_higher power [n = 14]; G2, gemcitabine [n = 12]; G3, combined gemcitabine and HIFU_low power [n = 12]; and G4, control ...
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