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Results 251 - 300 of 9400
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Park Tai Hwan TH Department of Neurology, Seoul Medical Center, Seoul, - - 2014
The safety and efficacy of intravenous tissue plasminogen activator (IV-TPA) in the 3- to 4.5-hour window were largely driven from Western populations, but have not been systematically explored in Korean population. We compared outcomes of acute ischemic stroke patients treated in the 3- to 4.5-hour window versus those in the ...
Tudorache Elena E Department of Paediatric Nephrology, Armand-Trousseau Hospital, APHP, Paris, France; University Pierre and Marie Curie, Paris 6, - - 2014
Henoch Schonlein purpura (HSP) is a common cause of paediatric renal disease in children, representing 10-15% of paediatric glomerulonephritis. This study examined the long-term outcome of biopsy proven HSP nephritis to identify correlations between disease development and treatment. Patients from three French centres were retrospectively analysed. We followed up 142 ...
Keino H H Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, - - 2014
PurposeTo evaluate the effect of infliximab over the initial 4 years of treatment on inflammatory ocular attacks and background retinal/disc vascular leakage in patients with refractory uveoretinitis associated with Behçet's disease.MethodsClinical records of nine patients were retrospectively reviewed. The main outcomes analyzed were frequency of ocular inflammatory attacks, background retinal ...
Gubler Christoph C Clinic of Gastroenterology and Hepatology, University Hospital of Zurich , Zurich , - - 2014
Abstract Objective. Optimal endoscopic treatment of gastric varices is still not standardized nowadays. Actively bleeding varices may prohibit a successful endoscopic injection therapy of Histoacryl® (N-butyl-2-cyanoacrylate). Since 2006, we have treated gastric varices by standardized endoscopic ultrasound (EUS) guided Histoacryl injection therapy without severe adverse events. Material and methods. We ...
Snyder Laura A LA Division of Neurological Surgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, - - 2014
Object Isthmic spondylolysis can significantly decrease functional abilities, especially in adolescent athletes. Although treatment can range from observation to surgery, direct screw placement through the fractured pars, or Buck's procedure, may be a more minimally invasive procedure than the more common pedicle screw-hook construct. Methods Review of surgical databases identified ...
Suhler Eric B EB Portland Veterans Administration Medical Center, Portland, Oregon; Oregon Health & Science University, Department of Ophthalmology/Casey Eye Institute, Portland, Oregon; Department of Public Health and Preventive Medicine, Oregon Health & Science University, Portland, Oregon. Electronic address: - - 2014
To determine whether rituximab, a monoclonal antibody against the B-lymphocyte antigen CD20, is effective in the treatment of refractory noninfectious scleritis. Prospective, dose-ranging, randomized, double-masked phase I/II clinical trial. Twelve patients with noninfectious scleritis refractory to systemic corticosteroid and ≥1 other systemic immunosuppressive agent were enrolled from January 2007 to ...
Komura Kazumasa K Department of Urology, Osaka Medical College, Osaka, Japan. Electronic address: - - 2014
To assess whether bipolar transurethral resection of the prostate using the TURis (Olympus, Tokyo, Japan) system demonstrates comparable efficacy and safety reporting 36 months of follow-up findings. The trial was registered at University hospital Medical Information Network Clinical Trials Registry in Japan (trial number UMIN 000010801). Patients were randomly selected to ...
Carrasco-Chinchilla Fernando F Unidad del Corazón, Hospital Universitario Virgen de la Victoria, Málaga, - - 2014
Symptomatic mitral regurgitation has an unfavorable prognosis unless treated by surgery. However, the European registry of valvular heart disease reports that 49% of patients with this condition do not undergo surgery. Percutaneous treatment of mitral regurgitation with MitraClip(®) has been proved a safe, efficient adjunct to medical treatment in patients ...
Coronel María Lorena ML Servicio de Neumología y Alergia Respiratoria, Institut Clínic del Tòrax, Hospital Clínic, Barcelona, España; División de Insuficiencia Cardíaca e Hipertensión Pulmonar, Instituto de Cardiología de Corrientes, Corrientes, - - 2014
Pulmonary endarterectomy (PE) is the treatment of choice for chronic thromboembolic pulmonary hypertension (CTEPH). The aim of this study was to analyze our experience in the medical and surgical management of CTEPH. We included 80 patients diagnosed with CTEPH between January 2000 and July 2012. Thirty two patients underwent PE ...
Pedrajas J M JM Servicio de Medicina Interna, Hospital Clínico San Carlos, Madrid, España. Electronic address: - - 2014
The Computerized Registry of Patients with Venous Thromboembolism (RIETE) is a prospective registry that consecutively includes patients diagnosed with venous thromboembolism. We compared the clinical presentation and response to anticoagulant treatment in patients with idiopathic venous thromboembolism (IVT) versus secondary venous thromboembolism (SVT, associated with a risk factor). We analyzed ...
Blaschi Wanessa - - 2014
Synchronization of estrus and ovulation is a reproductive technology of paramount importance in modern livestock improvement programs. It has a critical role for the implementation of assisted reproduction technologies that could increase productivity, including artificial insemination and embryo transfer. To this end, the aim of this study was to evaluate ...
Weitoft Tomas - - 2014
Intra-articular glucocorticoid treatment (IAGC) is widely used for symptom relief in arthritis. However, knowledge of factors predicting treatment outcome is limited. The aim of the present study was to identify response predictors of IAGC for knee synovitis in patients with rheumatoid arthritis (RA). In this study 121 RA patients with ...
Chaudry Gulraiz G Vascular Anomalies Center, Boston Children's Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA, 02115, USA, - - 2014
Sclerotherapy is the mainstay of treatment of macrocystic lymphatic malformation (LM), but the response using traditional sclerosants is much less beneficial in microcystic lesions. Intralesional bleomycin has been reported to be effective in microcystic LM; however, its use is limited by concerns about pulmonary fibrosis. The purpose of this study ...
Cavallini A A - - - 2014
Endovenous laser treatment (EVLT) is an accepted form of axial vein ablation for symptomatic venous reflux but its role in the treatment of anterior accessory saphenous vein (AASV) has not been well characterized. The aim of this paper is to show the short--term result of EVLT with a ball--tipped fiber ...
Guarnera G G IDI--IRCCS, Rome, Italy - - - 2014
No study of strong methodology could be found to resolve the controversy of optimal treatment of distal deep venous thrombosis (DDVT). Some inconclusive evidence exists on two approaches to care: anticoagulants and compression therapy or compression therapy and duplex scanning monitoring. Different studies report propagation to popliteal vein in 8% ...
Jevalikar Ganesh - - 2014
Abstract Background: Remission rates with antithyroid drugs (ATDs) in pediatric Graves' disease (GD) are low. Very few studies report long-term follow-up of GD especially into adulthood. Objectives: We studied long-term outcomes of pediatric onset GD, including a follow-up into adulthood and factors associated with need for definitive therapy. Methods: Sixty-five ...
Marinschek Sabine S Department for General Paediatrics and Psychosomatic, Medical University of Graz, Graz, Styria, - - 2014
The Graz model of tube weaning has been internationally recognised as a successful and rapid tube weaning program. Beside the onsite treatment option, a telemedical counselling was specifically developed in 2009. This study aims to show outcomes of this newly invented treatment in a large sample of patients. Our retrospective ...
Raymond J J From the Department of Radiology (J.R., A.W., F.G., D.R.), Centre Hospitalier de l'Université de Montréal and Laboratory of Interventional Neuroradiology (J.R., R.K.), Centre de recherche du Centre Hospitalier de l'Université de Montréal, Notre-Dame Hospital, Montreal, Quebec, Canada; Département de mathématiques et de statistique (M.C.), Université de Montréal, Montreal, Quebec, Canada; Department of Neurological Surgery (S.L.B.), Oregon Health & Science University, Portland, Oregon; Department of Radiology and Medical Imaging (A.J.E.), University of Virginia Health System, Charlottesville, Virginia; Department of Neurosurgery (J.M., B.L.H.), University of Florida, Gainesville, Florida; Departments of Radiology and Neurosurgery (A.S.T., R.D.T.), Medical University of South Carolina, Charleston, South Carolina; Service de Neuroradiologie Diagnostique et Interventionnelle (H.D.), Centre Hospitalier Universitaire de Nantes, Nantes, France; Department of Neurological Surgery (D.F.), Stony Brook University Medical Center, Stony Brook, New York; and Département de Neuroradiologie Diagnostique et Interventionnelle (S.B.), Centre Hospitalier Universitaire de Nancy, Nancy, France. - - 2014
Some patients with large or recurrent aneurysms may be at increased risk of recurrence postcoiling. The Patients Prone to Recurrence after Endovascular Treatment (PRET) trial was designed to assess whether hydrogel coils were superior to platinum coils in these high-risk patients. This article reports periprocedural safety and operator-assessed angiographic results ...
Aagaard E E Department of Oral and Maxillofacial Surgery, Odense University Hospital, Odense, Denmark. Electronic address: - - 2014
This study describes the clinical variables in 61 patients following total alloplastic temporomandibular joint reconstruction (TJR) in which the Biomet Microfixation Patient-Patient-Matched TMJ Implant was used. All patients were classified using the Wilkes classification. The visual analogue scale score for jaw pain intensity, the maximum inter-incisal opening (MIO), and the ...
Filardo Giuseppe G II Orthopaedic and Traumatology Clinic - Biomechanics and Technology Innovation Laboratory, Rizzoli Orthopaedic Institute, Bologna, - - 2014
Chronic Achilles tendinopathy is responsible for a severe reduction in physical performance and persistent pain. There is currently a number of therapeutic options and the local administration of growth factors is an emerging treatment strategy. In particular, platelet-rich plasma (PRP) is a widely used way to provide a local regenerative ...
Lévy Samuel S Aix-Marseille Université, 2 Place Delibes, 13008, Marseille, France, - - 2014
New oral anticoagulants (NOACs) have emerged as an alternative therapy to warfarin in the treatment of arterial and venous thromboembolism and in stroke prevention in patients with non-valvular atrial fibrillation (AF). Three of them, i.e., dabigatran, rivaroxaban, and apixaban, have been approved for clinical use in North America and in ...
Klekamp Jörg J Department of Neurosurgery, Christliches Krankenhaus, Danziger Str. 2, 49610, Quakenbrück, Germany, - - 2014
Basilar invagination is a rare craniocervical malformation which may lead to neurological deficits related to compression of brainstem and upper cervical cord as well as instability of the craniocervical junction. This study presents results of a treatment algorithm developed over a 20-year period focussing on anatomical findings, short-term and long-term ...
Teitelbaum Ezra N EN Department of Surgery, Northwestern University Feinberg School of Medicine, 676 North Saint Clair Street, Chicago, IL, 60611, USA, - - 2014
Peroral esophageal myotomy (POEM) is a new endoscopic operation for the treatment of achalasia. Here, we report 1-year physiologic and symptomatic outcomes following the procedure. POEM patients from a single-institution series who were more than 1 year removed from surgery were studied. Eckardt and GerdQ scores were obtained to assess symptoms. ...
Laver Lior L Department of Orthopaedic Surgery, Sports Medicine Unit, "Meir" Medical Center, The Sackler School of Medicine (Tel-Aviv University), Kfar-Saba, Israel, - - 2014
Syndesmotic sprains are uncommon injuries that require prolonged recovery. The influence of ultrasound-guided injections of platelet-rich plasma (PRP) into the injured antero-inferior tibio-fibular ligaments (AITFL) in athletes on return to play (RTP) and dynamic stability was studied. Sixteen elite athletes with AITFL tears were randomized to a treatment group receiving ...
Tahar Rachida R Unité Mixte de Recherche 216 Mère et Enfant Face aux Infections Tropicales, Institut de Recherche pour le Développement (IRD), Unité de formation et de recherche (UFR) de Pharmacie, 75270 Paris, France Laboratoire de Recherche sur le Paludisme, Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale (OCEAC), B.P. 288, Yaoundé, - - 2014
 Artemisinin-based combination therapies (ACTs) are recommended for the treatment of acute uncomplicated falciparum malaria in many endemic countries. Despite the emergence of artemisinin resistance, few alternative non-ACTs, including atovaquone-proguanil, are currently available.  Plasmodium falciparum-infected Cameroonian children≤5 years old (n=338) were randomized to artesunate-amodiaquine, atovaquone-proguanil, or artesunate-atovaquone-proguanil treatment groups and followed ...
Flachenecker Peter P Neurological Rehabilitation Centre Quellenhof, Bad Wildbad, - - 2014
Background: Nabiximols (Sativex®), in a cannabinoid-based oromucosal spray, is an add-on therapy option for patients with moderate to severe multiple sclerosis spasticity (MSS) resistant to other medications. The study objective was to provide long-term data on clinical outcomes, tolerability, quality of life and treatment satisfaction for MSS patients receiving nabiximols ...
Boccon-Gibod Laurent L Membre de l'Académie de Chirurgie, Expert près les Tribunaux, Paris, - - 2014
Guidelines for prostate cancer treatment suggest that intermittent androgen deprivation (IAD) can be considered for certain patients. To evaluate the efficacy and safety of degarelix as IAD for one or more treatment cycle(s) in prostate cancer patients requiring androgen deprivation. This open-label uncontrolled multicenter study included patients with prostate-specific antigen ...
Lohrer Heinz H Institute for Sports Medicine Frankfurt am Main , Otto-Fleck-Schneise 10, 60528, Frankfurt/Main, Germany, - - 2014
The results of operative treatment for recalcitrant midportion Achilles tendinopathy and recalcitrant retrocalcaneal bursitis were evaluated using the patient administered, disease specific, and validated VISA-A-G questionnaire. A cohort of 89 patients was prospectively followed. These patients underwent operations for sport induced midportion Achilles tendinopathy (39 procedures) or retrocalcaneal bursitis (55 ...
Cakir Volkan V Ataturk Training and Research Hospital, Department of Radiology, Division of Ä°nterventional Radiology, Katip Celebi University, Izmir, Turkey, - - 2014
The purpose of this study was to compare the efficacy of percutaneous aspiration thrombectomy (PAT) followed by standard anticoagulant therapy, with anticoagulation therapy alone, for the treatment of acute proximal lower extremity deep vein thrombosis. In this randomised, prospective study, 42 patients with acute proximal iliofemoral deep vein thrombosis documented ...
Dapul Geraldine G Department of Physical Medicine and Rehabilitation Oakwood, School of Medicine, Wayne State University, Dearborn, MI, - - 2014
Severe tetanus remains a serious issue in less developed countries, leading to prolonged hospitalization due to prolonged neuromuscular contraction of muscles. We present a case of severe tetanus in the United States that was successfully managed with intrathecal baclofen. A 42-year-old male without tetanus vaccination history presented to the emergency ...
Neggers S J C M M SJ Department of Medicine, Endocrinology section, Pituitary Center Rotterdam, Erasmus University Medical Center Rotterdam, the - - 2014
Background: Treatment for acromegaly patients with long-acting somatostatin receptor ligands (LA-SRIFs) does often not result in complete normalization of insulin-like growth factor 1 (IGF-I). Addition of pegvisomant, a growth hormone receptor antagonist (PEGV), could improve this, however the literature has not described long-term follow-up. Objective: To assess long-term efficacy and ...
Bayoumi A M AM Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia. Electronic address: - - 2014
Temporomandibular joint (TMJ) dislocation is an excessive forward movement of the condyle beyond the articular eminence with complete separation of the articular surfaces and fixation in that position. This study was conducted to assess autologous blood injection to the TMJ for the treatment of chronic recurrent TMJ dislocation. Fifteen patients ...
Monk Bradley J BJ Creighton University School of Medicine and University of Arizona Cancer Center at St Joseph's Hospital, Phoenix, AZ, USA. Electronic address: - - 2014
Angiogenesis is a valid target in the treatment of epithelial ovarian cancer. Trebananib inhibits the binding of angiopoietins 1 and 2 to the Tie2 receptor, and thereby inhibits angiogenesis. We aimed to assess whether the addition of trebananib to single-agent weekly paclitaxel in patients with recurrent epithelial ovarian cancer improved ...
Takeuchi Masaru M Department of Ophthalmology, National Defense Medical College, Tokorozawa, Japan. Electronic address: - - 2014
To evaluate the long-term efficacy and safety of infliximab for the treatment of uveitis in Behçet's disease (BD). Retrospective multicenter study using a questionnaire. A total of 164 consecutive patients with BD treated with infliximab for more than 1 year were studied. The mean age at initiation of infliximab treatment ...
Fokkenrood H J P HJ Department of Vascular Surgery, Catharina Hospital, Eindhoven, The Netherlands; CAPHRI Research School, Maastricht University, Maastricht, The - - 2014
International guidelines recommend supervised exercise therapy (SET) as primary treatment for intermittent claudication (IC). The aim of this study was to calculate treatment costs in patients with IC and to estimate nationwide annual savings if a stepped care model (SCM, primary SET treatment followed by revascularization in case of SET ...
Mavropoulou Antonia A Department of Veterinary Sciences, University of Parma, Via del Taglio 10, Parma 43126, - - 2014
This study shows that a combination of doxycycline (10mg/kg/sid for 30 days) and ivermectin (6μg/kg/every 15 days for 6 months) is well tolerated for the treatment of canine heartworm disease (HWD). Monthly echocardiography showed that 84% of treated dogs either progressively improved parameters indicative of pulmonary hypertension or, following slight ...
Moojen Dirk Jan F DJ Department of Orthopaedic Surgery and Traumatology , Joint Research, Onze Lieve Vrouwe Gasthuis , - - 2014
Background - Treatment of an acute total hip arthroplasty (THA) infection aims at control of the infection with retention of the implant by surgical debridement and antibiotic treatment. There is no clear evidence whether a single surgical debridement is sufficient or whether multiple procedures are necessary for optimal treatment. Methods ...
Turgutalp Kenan K Department of Internal Medicine, Division of Nephrology, Mersin University , Mersin , Turkey - - 2014
Abstract Background: Novel biomarkers are needed to predict the response to treatment in patients with nephrotic syndrome (NS) due to primary glomerulonephritides (PGN). We aimed to test the predictive value of red blood cell distribution width (RDW) for estimation of response to therapy in adult patients with NS. Study design, ...
Yang Rong R The affiliated drum tower hospital of Nanjin University, school of medicine, Urology, Nanjing, Jiangsu, China ; - - 2014
Purpose: To analyze the feasibility, safety and therapeutic effects of retroperitoneoscopic-guided cool-tip radiofrequency ablation (RCRFA) used for the treatment of adrenocortical aldosteronoma. Patients and methods: We performed a retrospective comparasion of RCRFA (n=12) and laparoscopic partial adrenalectomy (LPA) (n=26) in the patients with solitary aldosterone-producing adenoma in our center from ...
Foucrier Arnaud A From the *Department of Anesthesiology and Critical Care, University Pierre et Marie-Curie-Paris 6, Assistance Publique-Hôpitaux de Paris, Paris, France; †Hospital Pitié-Salpétrière, Paris, France; ‡Department of Anaesthesia, Perioperative Research Group, University of KwaZulu-Natal, Pietermarizburg, South Africa; §The Perioperative Research Group, Population Health Research Institute, Hamilton, Ontario, Canada; ‖Biostatistical and Clinical Epidemiology Department, Faculty of Medicine, Nimes University Hospital, Montpellier 1 University, Montpellier, France; and ¶Departments of Anesthesia & Clinical Epidemiology and Biostatistics, Michael DeGroote School of Medicine, Faculty of Health Sciences, McMaster University and Population Health Research Institute, David Braley Cardiac, Vascular and Stroke Research Institute, Perioperative Medicine and Surgical Research Unit, Hamilton, Ontario, - - 2014
Acute cardiac events are a frequent cause of morbidity after vascular surgery. The impact of early evidence-based treatment for patients with an acute cardiac event after vascular surgery on long-term postoperative outcomes has not been extensively studied. We hypothesized that providing appropriate evidence-based treatment to patients with elevated postoperative cardiac ...
Li Julius J South Texas Veterans Health Care System, San Antonio, TX, USA The University of Texas at Austin College of Pharmacy, Austin, TX, USA Pharmacotherapy Education and Research Center, University of Texas Health Sciences Center San Antonio, San Antonio, TX, USA - - 2014
Contrary to prior case reports describing occasional clinical failures with cefazolin for methicillin-susceptible Staphylococcus aureus (MSSA) infections, recent studies demonstrated no difference in outcomes between cefazolin and antistaphylococcal penicillins for the treatment of MSSA bacteremia. While promising, these studies had low frequencies of high inoculum infections, such as endocarditis. This ...
Tawfik Abeer Attia AA Dermatology Unit, Department of Medical Applications of Lasers, National Institute of Laser Enhanced Sciences, Cairo University, Giza, - - 2014
Pulsed dye laser has been used successfully in the treatment of nail psoriasis. Intense pulsed light (IPL) has been used in the treatment of plaque psoriasis using a 550-nm filter. To study the efficacy of IPL in the treatment of nail psoriasis. Twenty patients with finger and toe nail psoriasis ...
Tsze Daniel S DS Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, New York - - 2014
We present the case of a 3-month-old girl who had unrepaired Tetralogy of Fallot who presented to the emergency department with an acute hypoxic episode. The patient was hyperpneic and cyanotic, with an initial oxygen saturation of 56%. She did not respond to knee-to-chest positioning. A single dose of intranasal ...
Franco Matheus Cavalcante MC Matheus Cavalcante Franco, Gustavo Flores Gomes, Frank Shigeo Nakao, Gustavo Andrade de Paulo, Angelo Paulo Ferrari Jr, Ermelindo Della Libera Jr, Digestive Endoscopy Unit, Division of Gastroenterology, Federal University of São Paulo, São Paulo 04023-900, - - 2014
To evaluate the efficacy and safety of undiluted N-butyl-2 cyanoacrylate plus methacryloxysulfolane (NBCM) as a prophylactic treatment for gastric varices (GV) bleeding. This prospective study was conducted at a single tertiary-care teaching hospital between October 2009 and March 2013. Patients with portal hypertension (PH) and GV, with no active gastrointestinal ...
Ridderstråle Martin M Steno Diabetes Center, Gentofte, Denmark. Electronic address: - - 2014
Metformin is the recommended first-line pharmacotherapy for patients with type 2 diabetes. There is no consensus on the optimum second-line pharmacotherapy. We compared the efficacy and safety of the sodium glucose cotransporter 2 inhibitor empagliflozin and the sulfonylurea glimepiride as add-on to metformin in patients with type 2 diabetes. In ...
Wang Tang-Chuan TC Department of Otolaryngology, China Medical University Hospital, Taichung, - - 2014
The purpose of the study was to perform a systematic review and meta-analysis of the literature to compare the efficacy (and other postoperative outcomes) of nonabsorbable versus absorbable nasal packing after functional endoscopic sinus surgery (FESS) for the treatment of chronic rhinosinusitis. Studies were considered for inclusion if they were ...
Nutman Amir A Division of Epidemiology, Tel Aviv- Sourasky Medical Center, Tel-Aviv, - - 2014
Carbapenem-resistant Acinetobacter baumannii (CRAB) is an increasingly common nosocomial pathogen. We sought to identify clinical and microbiological predictors of 14-day mortality among patients with CRAB bacteremia. This case-control study included all adult patients in one Israeli hospital with CRAB on blood culture between July 2008 and June 2011. Cases were ...
Hayashi Nobukazu N Department of Dermatology, Toranomon Hospital, Tokyo, - - 2014
The efficacy of adapalene for acne treatment has been established. However, because of local adverse reactions, a fair number of patients discontinue adapalene treatment before experiencing its effects. To examine the usefulness of moisturizers concomitant with adapalene on adherence to treatment and its therapeutic effects in patients, 100 patients with ...
Rintoul Robert C RC Department of Thoracic Oncology, Papworth Hospital, Cambridge, - - 2014
Malignant pleural mesothelioma incidence continues to rise, with few available evidence-based therapeutic options. Results of previous non-randomised studies suggested that video-assisted thoracoscopic partial pleurectomy (VAT-PP) might improve symptom control and survival. We aimed to compare efficacy in terms of overall survival, and cost, of VAT-PP and talc pleurodesis in patients ...
Roussin A A Internal and Vascular Medicine, Centre Hospitalier de l'Université de Montréal, Montreal, Canada - - - 2014
Deep vein thrombosis (DVT) is a manifestation of venous thromboembolism (VTE) and accounts for most venous thromboembolic events. Although DVT is not directly lifethreatening, thrombi in the proximal veins of the leg can embolize to the lungs to form a pulmonary embolism, which may prove rapidly fatal. If untreated, DVT ...
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