Search Results
Results 201 - 250 of 9713
< 1 2 3 4 5 6 7 8 9 10 >
Hao Dingjun D aDepartment of Spine Surgery, Honghui Hospital Affiliated of Xi'an Jiaotong University, Xi'an 710054, China bDepartment of General Surgery, No. 417 Hospital of Nuclear Industry, Xi'an 710600, - - 2014
Study Design. A randomized, controlled clinical trial.Objective. This randomized controlled clinical trial was aimed at comparing the clinical outcomes of combined posteroanterior (P-A) fusion and transforaminal thoracic interbody fusion (TTIF) in cases of thoracolumbar fracture-dislocation.Summary of Background Data. The optimal treatment strategy for thoracolumbar fracture-dislocation remains controversial.Methods. Sixty-one patients presenting ...
Shemer A A Department of Dermatology, Chaim Sheba Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel Aviv, - - 2014
Clinical studies regarding complete cure rate of onychomycosis using oral Terbinafine have a very broad range (14-90%) based solely on response to treatment on the big toenail. To evaluate the efficacy of Terbinafine in all affected onychomycotic toenails and, furthermore, to evaluate differences in mycological, clinical and complete cure rate ...
Park Chan Hyuk CH Division of Gastroenterology, Department of Internal Medicine, Severance Hospital, Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Republic of - - 2014
Self-expandable metal stent (SEMS) placement and palliative gastrojejunostomy (GJJ) are palliative treatment options for malignant gastric outlet obstruction. To compare clinical outcomes of palliative treatments for gastric outlet obstruction caused by unresectable gastric cancer. Retrospective study. University-affiliated tertiary-care hospital in the Republic of Korea. Two hundred fifty-six patients with gastric ...
Ong Wee Loon WL William Buckland Radiotherapy Centre, Alfred Health, Melbourne, Australia; Department of Public Health and Primary Care, University of Cambridge, United - - 2014
Erectile function (EF) is commonly affected following prostate cancer treatment. We aim to evaluate the long-term EF following seed brachytherapy (BT) treatment. The study consisted of 366 patients treated with BT at our institution, who completed the IIEF-5 questionnaire and reported no or mild erectile dysfunction (ED) pre-BT. The probability ...
Giles Kristina A KA Section of Vascular and Endovascular Surgery, Department of Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, - - 2014
Bone marrow cell therapy (BMCT) for patients with critical limb ischemia (CLI) is a potential treatment in candidates with poor options for standard revascularization procedures. Whereas clinical trials are ongoing, there are few comparative data to assess its efficacy compared with bypass. Patients with poor revascularization options underwent BMCT between ...
Mariani Lisa - - 2014
The purpose of this retrospective study is to investigate the dentoalveolar and skeletal effects of two distalizing protocols featuring different anchorage systems used in patients with class II malocclusion: the MGBM system (skeletal anchorage) and Pendulum (intraoral anchorage). The sample comprised 57 patients who were assigned to one of the ...
Yri H M HM Danish Headache Center, Department of Neurology, Glostrup Hospital, University of Copenhagen, Glostrup, - - 2014
Our aim was to prospectively describe the course of headache during the first year of idiopathic intracranial hypertension (IIH). Patients with newly diagnosed IIH were consecutively included from December 2010 to June 2013. Treatment according to standard guidelines was initiated. Headache history was obtained by headache diaries and standardized interviews ...
Landewé Robert R Academic Medical Center, Amsterdam, The - - 2014
Objective: A longitudinal integration approach evaluated all radiographic scores assessed over 10 years, rather than only completer data, from 2 studies of adalimumab (ADA) for rheumatoid arthritis (RA). Methods: DE019 (methotrexate [MTX]-inadequate responders, long-standing RA) and PREMIER (MTX-naïve, early RA) had, respectively, 1- or 2-year double-blind periods followed by 9- ...
Chaus George W GW *Department of Orthopaedic Surgery, University of Colorado, Denver †Department of Pediatric Orthopaedic Surgery, Musculoskeletal Research Center, Children's Hospital Colorado, Aurora, - - 2014
Displaced proximal humeral physeal fractures (PHPF) are rare injuries. Because of the lack of comparative studies, treatment has historically been based on surgeon preference. The purpose of this study was to compare treatment outcomes among skeletally immature patients who underwent operative versus nonoperative treatment for Neer-Horwitz (NH) III or IV ...
Pao Jwo-Luen JL *Institute of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, Taiwan †Department of Minimally Invasive Spine Surgery, Far-Eastern Memorial Hospital, New Taipei, Taiwan ‡Department of Orthopedic Surgery, Far-Eastern Memorial Hospital, New Taipei, Taiwan §Department of Mechanical Engineering, College of Engineering, National Taiwan University, Taipei, - - 2014
A retrospective case series study. To investigate the clinical significance of post-decompression facet effusion (PDFE) after microendoscopic decompressive laminotomy (MEDL). The facet joint effusion noted on MRI was considered as an indicator of degeneration of the facet joints and segmental instability. PDFE occurred after MEDL might imply post-decompression segmental instability. ...
Gerding Heinrich H Augenzentrum Klinik Pallas, Olten, Switzerland Department of Ophthalmology, University of Muenster, Muenster, - - 2014
Retinal vein occlusion (RVO) is a common cause of retinal vascular disease, resulting in potentially irreversible loss of vision despite the existence of several therapeutic options. The humanised monoclonal antibody fragment ranibizumab binds to and inhibits vascular endothelial growth factor, a key driver of macular oedema in RVO. In 2010, ...
Dwarakanath Srinivas S Department of Neurosurgery, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore 560029, Karnataka, - - 2014
Surgical management of tremor has evolved over the years with Deep Brain Stimulation (DBS) gradually supplanting lesioning as the mainstay in treatment. In this article, the largest of its kind from our country, we present our experience in the use of lesioning in the management of patients with multietiological tremors. ...
Karabulut Kagan K Department of General Surgery, Ondokuz Mayis University Medical School, Samsun, - - 2014
The aim of this study was to evaluate long-term outcome of the intraoperative and perioperative albendazole (ALB) treatment on the recurrence and/or secondary hydatidosis. One hundred and one patients with hepatic hydatidosis were treated intraoperatively and perioperatively with ALB, in addition to surgery. Perioperative ALB treatment was given in a ...
Otsuki Hideo H Nagakubo hospital, urology, Kunitachi, Japan ; - - 2014
Objectives: To assess the long-term durability of Photoselective Vaporization of the Prostate (PVP) for symptomatic benign prostatic enlargement (BPE) or obstruction (BPO) and treatment efficacy for large BPE. Methods: 457 patients with symptomatic BPE underwent PVP between January 2006 and April 2009. Efficacy was evaluated with IPSS, QOL score, urinary ...
Proctor Steven L - - 2014
Objective: This study sought to compare the effectiveness of the 3 most commonly prescribed maintenance medications in the United States indicated for the treatment of opioid dependence in reducing illicit drug use and retaining patients in treatment. Method: Data were abstracted from electronic medical records for 3,233 patients admitted to ...
Caltik Yilmaz Aysun A Department of Pediatric Nephrology, Dr. Sami Ulus Children Hospital , Ankara , - - 2014
Abstract Background: The prognostic factors, the outcome and the most favorable treatment regimen are not entirely known for children with membranoproliferative glomerulonephritis (MPGN). MPGN is a rarely observed disease more prevalent in adolescents, so we aimed to review the clinical and histological properties, treatments and the outcome of our patients ...
Nucci Paolo P University Eye Clinic San Giuseppe, San Giuseppe Hospital, University of Milan , Milan , Italy - - 2014
Abstract Purpose: To evaluate the five-year stability of frontalis suspension of the upper eyelid with a silicone band for the treatment of severe congenital ptosis in infants. Methods: Chart review of pediatric patients with a follow-up of five years after unilateral frontalis suspension with silicone band was reviewed. Margin-reflex distance ...
Shiber Shachaf S Rabin Medical Center, Beilinson Hospital, Department of Emergency Medicine, Petah Tikva, Israel ; - - 2014
Background: Glucocorticoid (GC) therapy has been shown to prevent Graves' ophthalmopathy (GO) progression following radioiodine (RAI) treatment. However, the optimal regimen is controversial with studies from recent years suggesting the use of lower doses and shorter GC treatment courses. Methods: Systematic review and meta-analysis of randomized controlled trials (RCTs) and ...
Parlar B B Department of Dermatology, University Hospital Bern (Inselspital), University of Bern, Bern, - - 2014
Telangiectasias of the lower extremities are very common. There are no blinded, randomized, controlled clinical trials comparing laser modalities with the gold standard sclerotherapy, while the few available studies encompass small patients cohorts. This prospective, randomized, open-label trial compares the efficacy of sclerotherapy with polidocanol vs. long-pulsed neodymium-doped yttrium aluminium ...
Moore Grant H GH Department of Oculoplastic Surgery, Jules Stein Eye Institute, UCLA, Los Angeles, CA, - - 2014
An 87-year-old man with a history of relapsing polychondritis presented to the emergency department after 4 days of worsening left periorbital swelling and erythema. On examination, he demonstrated clinical features consistent with orbital cellulitis and was treated with a trial of intravenous antibiotics. His condition did not improve over the ...
Hill T L TL The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, - - 2014
Benign urethral obstructions (BUO) in dogs result in substantial morbidity because of challenges with conventional therapies. Treatment of malignant urethral obstructions with intraluminal urethral stents is reported to successfully relieve obstructions. To evaluate the efficacy and outcome of urethral stent placement for treatment of BUO in dogs. Eleven client-owned animals ...
Stromps Jan-Philipp JP *Department of Plastic Surgery, Hand Surgery, Burn Center, University Hospital RWTH Aachen, Aachen, Germany; †The Unit of Plastic Surgery, Carmel Medical Center, Haifa, - - 2014
A variety of therapeutic procedures for treating keloids have been previously reported, with varying success and recurrence rates. As a monotherapy, intralesional cryosurgery has yielded convincing clinical results. We combined intralesional cryosurgery with the application of topical silicone gel sheeting. In this retrospective study, which was conducted between 2008 and ...
Rusu Irene M IM *Department of Ophthalmology, New York University School of Medicine, New York, New York; †Vitreous Retina Macula Consultants of New York, New York, New York; ‡Department of Ophthalmology, Columbia University College of Physicians and Surgeons, New York, New York; §Edward S. Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, New York; ¶LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear and Throat Hospital, New York, New York; and **Regeneron, Tarrytown, New - - 2014
To assess for change in intraocular pressure (IOP) in neovascular age-related macular degeneration patients switched to aflibercept after receiving previous treatments of intravitreal bevacizumab or ranibizumab. This is a retrospective chart review of the first 53 patients (53 eyes) treated with at least 2 injections of 2 mg in 0.05 ...
Markley Herbert G HG *New England Regional Headache Center, Worcester, MA †A&A Pain Institute of St. Louis, St. Louis, MO ‡Depomed Inc., Menlo Park, - - 2014
To evaluate the safety and effectiveness of once-daily gastroretentive gabapentin (G-GR) for treatment of PHN in real-world clinical practice. Patients aged ≥18 years were divided into 2 cohorts: patients ≤70 years and patients >70 years. All patients were titrated to 1800 mg G-GR/d over 2 weeks and maintained at that ...
Cornely Oliver A OA Department of Internal Medicine, Clinical Trials Centre Cologne, ZKS Köln, BMBF 01KN1106, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50924 Cologne, Germany - - 2014
To evaluate the efficacy of fidaxomicin treatment, which has a limited effect on the normal gut flora, compared with vancomycin and metronidazole treatment in Clostridium difficile infections (CDIs). A systematic literature review was conducted in July to August 2011 and updated in July 2013. For fidaxomicin versus vancomycin, efficacy was ...
Baudry Clotilde C Department of Gastroenterology, University Hospital of Saint-Louis, Paris, France. Electronic address: - - 2014
After intestinal resection for Crohn's disease, the severity of endoscopic recurrence in the first year following surgery is predictive of clinical outcome. Aim of the study was to assess the impact on clinical recurrence of tailored therapy based on endoscopic findings in the first year following surgery for Crohn's disease. ...
Taha Ashraf G AG Division of Vascular Surgery, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pa; Department of Vascular Surgery, Assiut University, Assiut, - - 2014
Thrombolysis and open surgical revascularization are current options for the treatment of acute limb ischemia (ALI). Despite the several randomized controlled trials comparing the two options, no single treatment can yet be recommended as a universal initial management of ALI. The purpose of this study was to evaluate contemporary endovascular ...
Burri Christian C Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland; Kinshasa School of Public Health, Kinshasa, Democratic Republic of the Congo; Medicines for Malaria Venture, Geneva, - - 2014
Cases of delayed hemolytic anemia have been described after treatment with injectable artesunate, the current World Health Organization-recommended first-line drug for the treatment of severe malaria. A total of 350 patients (215 [61.4%] < 5 years of age and 135 [38.6%] ≥ 5 years of age) were followed-up after treatment ...
Dzakpasu Mawuli M Centre for Water Resources Research, School of Civil, Structural and Environmental Engineering, Newstead Building, University College Dublin, Belfield, Dublin 4, Ireland, - - 2014
Due to the nature of the phosphorus (P) removal mechanisms associated with constructed wetlands, the sustainability of P treatment is usually of high interest. As a result, a 4-year dataset from a typical multi-celled integrated constructed wetland (ICW) located at Glaslough in Co. Monaghan, Ireland was evaluated to determine the ...
Darawankul Budsakorn B Division of Rheumatology, Department of Internal Medicine, Phramongkutklao Hospital and College of Medicine, 315 Rajavithee Road, Bangkok, 10400, Thailand, - - 2014
The purpose of this study was to identify the prevalence and prognostic factors of clinical remission in patients with rheumatoid arthritis (RA). The Thai Army Rheumatoid Arthritis Cohort (TARAC) patients were included if baseline data were available. Clinical remission was defined as 28-joint count disease activity scores (DAS28) <2.6 in ...
Roozeboom M H MH Department of Dermatology, Maastricht University Medical Centre, Maastricht, the Netherlands; GROW Research Institute for Oncology and Developmental Biology, Maastricht University, Maastricht, the - - 2014
A recent non-inferiority randomised controlled trial (RCT) indicated that imiquimod can be considered as superior to methylaminolevulinate photodynamic therapy (MAL-PDT) in treatment of superficial basal cell carcinoma (sBCC). Knowledge of treatment effectiveness in subgroup of patients is of great value in clinical practice to select the most effective treatment for ...
Brandt Alexander Sascha AS Department of Urology, HELIOS Klinikum Wuppertal, University of Witten/Herdecke, Wuppertal, - - 2014
Objective: To evaluate the therapeutic effect of tamoxifen monotherapy in patients with retroperitoneal fibrosis (RPF). Patients and Methods: From 2007 on, 31 patients with idiopathic RPF were treated with tamoxifen monotherapy. Follow-up investigations included magnetic resonance imaging, laboratory measurements, registration of side effects and changes or removal of ureteral stents. ...
Lawitz Eric E Texas Liver Institute, University of Texas Health Science Center, San Antonio, TX, USA. Electronic address: - - 2014
Interferon-free regimens are needed to treat hepatitis C virus (HCV) infections. We investigated the efficacy of combined simeprevir and sofosbuvir. We enrolled patients with chronic HCV genotype 1 infections who had previously not responded to pegylated interferon (peginterferon) and ribavirin or were treatment naive. Patients were randomly assigned in a ...
Manns Michael M Hannover Medical School, Hannover, Germany; German Center for Infection Research (DZIF), Hannover-Braunschweig, Germany. Electronic address: - - 2014
An unmet need exists for interferon-free and ribavirin-free treatments for chronic hepatitis C virus (HCV) infection. In this study, we assessed all-oral therapy with daclatasvir (NS5A replication complex inhibitor) plus asunaprevir (NS3 protease inhibitor) in patients with genotype 1b infection, including those with high unmet needs or cirrhosis, or both. ...
Virgili A A Dipartimento di Scienze Mediche, Sezione di Dermatologia e Malattie Infettive, Università degli Studi di Ferrara, Ferrara, - - 2014
Evidence on the treatment of plasma cell vulvitis (PCV) is scarce and comparative studies are lacking. To assess and compare the effectiveness and safety, on a long-term basis, of three topical interventions for the treatment of PCV. Retrospectively collected efficacy and safety data of a cohort of PCV patients treated ...
Kim Lily H LH Division of Gastroenterology and Hepatology, Stanford University Medical Center, 750 Welch Road, Suite 210, Palo Alto, CA, 94304, USA, - - 2014
Data on usage of antiviral therapy and application of chronic hepatitis B (CHB) management guidelines in different settings are limited. Our goal is to evaluate the proportion of treatment-eligible patients by 6-month follow-up and treatment rate among eligible patients by 12-month follow-up in diverse settings. In this retrospective cohort study, ...
Watanabe Shinya S Katsuta Hospital Mito GammaHouse, - - 2014
Object Recently, an increasing number of patients with brain metastases, even patients over 80 years of age, have been treated with stereotactic radiosurgery (SRS). However, there is little information on SRS treatment results for patients with brain metastases 80 years of age and older. The authors undertook this study to ...
Kollewe Katja K Movement Disorders Section, Department of Neurology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany, - - 2014
Botulinum toxin (BT) therapy is the treatment of choice for blepharospasm (BPS). Currently available BT type A drugs include Botox(®), Dysport(®) and Xeomin(®). Until now, there are few long-term studies on BT therapy for BPS. This is the first long-term study comparing all three major BT drugs. We collected treatment, ...
Lucky M M Wirral University Teaching Hospital NHS Foundation - - 2014
To review outcomes of the treatment of carcinoma in situ of the penis at a large supra-regional penile cancer network, where centralisation has permitted greater experience with treatment outcomes, and suggest treatment strategies. The network penile cancer database which details presentation, treatment and complications was analysed from 2003-10, identifying patients ...
Zhong Shu-Xia - - 2014
Abstract Background. The long-pulsed 1064-nm Nd:YAG laser is effective for treating port-wine stain (PWS). This study evaluated the efficacy and safety of Nd:YAG laser in treating PWS in Chinese patients. Methods. A retrospective study of 130 PWS patients treated with long-pulsed 1064-nm Nd:YAG laser from 2009 to 2011. Results. After ...
Ogura Yuichiro Y Department of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Science, Nagoya, Japan. Electronic address: - - 2014
To evaluate intravitreal aflibercept for treatment of macular edema secondary to central retinal vein occlusion (CRVO). Randomized, double-masked, phase 3 study. 177 patients with macular edema secondary to CRVO were randomized to receive 2 mg intravitreal aflibercept (n=106) or sham (n=71) every 4 weeks for 20 weeks. From weeks 24 ...
Metsaars W P WP Department of Orthopaedics and Walaeus Library, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: - - 2014
To conduct a systematic review and meta-analysis of the literature evaluating treatment outcome for supination deformity in obstetric brachial plexus injury. We included studies on brachial plexus and supination deformity with follow-up of at least one year and quantitative measurements of forearm mean passive pronation and position at rest. Meta-analysis ...
Basura Gregory J GJ Division of Otology/Neurotology, Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann - - 2014
To compare the efficacy of treatments commonly offered to patients with Ménière's disease who fail conservative medical therapy including diuretics and a sodium-restricted diet. This study compared three second-echelon treatments: the Meniett device, endolymphatic sac decompression, and intratympanic gentamicin injections to determine their comparative effectiveness and capacity to mitigate against ...
Navarrete-Sanchis Javier J Department of Ophthalmology, Hospital Universitario de La Ribera, Crtra Corbera, Km. 1, 46600, Alzira, Spain, - - 2014
The aim of this study is to assess whether the outcome of pars plana vitrectomy for the treatment of cystoid non-tractional diabetic macular edema is stable and durable. A prospective longitudinal analysis of central macular thickness and visual acuity was performed, using repeated-measures ANOVA, in 22 subjects with cystoid diabetic ...
Petelin Milan M Department of Oral Medicine and Periodontology, University of Ljubljana, Faculty of Medicine, Hrvatski trg 6, 1000, Ljubljana, Slovenia, - - 2014
The aim of this study was to compare the effect of subgingival ultrasonic scaling followed by repeated (three times) antimicrobial photodynamic therapy (PDT), ultrasonic scaling alone (US), and scaling and root planing with hand instruments (SRP) for initial periodontal treatment. Twenty-seven non-smoking systemically healthy chronic periodontitis patients were included. Residual ...
Kerr Dana D The Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, NH, 03756, - - 2014
Although previous studies have illustrated improvements in surgical cohorts for patients with intervertebral disc herniation, there are limited data on predictors of long-term outcomes comparing surgical and nonsurgical outcomes. We assessed outcomes of operative and nonoperative treatment for patients with intervertebral disc herniation and symptomatic radiculopathy at 8 years from the ...
Mitra D D From the Departments of Neuroradiology (D.M., V.J., A.G.), Neurosurgery (P.M.), and Anesthesiology and Intensive Care (A.V.), Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom; and Institutes of Aging and Health (P.W.) and Neurosciences (B.G.), Newcastle University, Newcastle upon Tyne, United Kingdom. - - 2014
Management of poor-grade subarachnoid hemorrhage is based on limited evidence from small single-center retrospective observational studies. The purpose of this study was to undertake a single-center randomized controlled feasibility trial comparing a strategy of early endovascular aneurysm treatment with treatment after neurologic recovery in this group of patients. Patients with ...
Moradiya Yogesh Y From the Division of Neurosciences Critical Care (Y.M., S.B.M., W.C.Z.), Department of Neurology (D.E.N.-T.), Division of Brain Injury Outcomes (D.F.H.), Johns Hopkins University School of Medicine, Baltimore, MD. - - 2014
Intraventricular thrombolysis (IVT) is a promising treatment in facilitating intraventricular clot resolution after intraventricular hemorrhage. We examined in-hospital outcomes and resource utilization after thrombolysis in patients with intraventricular hemorrhage requiring ventriculostomy in a real-world setting. We identified adult patients with primary diagnosis of nontraumatic intracerebral hemorrhage requiring ventriculostomy from the ...
Akarsu S S Department of Physical Medicine & Rehabilitation, Haydarpaşa Training Hospital, İstanbul, Turkey - - 2014
The aim of this study was to determine the efficacy of single versus repetitive injection of lignocaine into the carpal tunnel for the management of carpal tunnel syndrome. The 42 patients included were randomly assigned to two Groups: group 1 was injected with 4 mL of 1% lignocaine once and ...
Drobne David D University Hospitals Leuven, Department of Gastroenterology, Leuven, - - 2014
The addition of immunomodulators increases the efficacy of maintenance therapy with infliximab, for up to 1 year, in patients with Crohn's disease who have not been previously treated with immunomodulators. However, there are questions about the effect of withdrawing immunomodulator therapy from these patients. We studied the effects of treatment ...
< 1 2 3 4 5 6 7 8 9 10 >