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Perez Ronen R *Department of Otolaryngology-Head and Neck Surgery, Shaare Zedek Medical Center affiliated with the Hebrew University Medical School, Jerusalem; †EStimME, Tel-Aviv, Israel; and ‡University of Michigan Health System, Otolaryngology -Head and Neck Surgery, Ann Arbor, Michigan, - - 2014
To assess the safety and efficacy of multiple sessions of electrostimulation by a transtympanic needle electrode on the promontory for tinnitus relief. Prospective open, unblinded, uncontrolled clinical trial. Tertiary academic referral center. Ten patients (8 male and 2 female subjects), mean age 50.1 ± 12 years (range, 34-67) with severe ...
Huang Wei-Zhao WZ Cardiothoracic Surgery Department, Zhongshan People's Hospital (Zhongshan Hospital of Sun Yat-sen University), Zhongshan 528403, - - 2014
Methods We retrospectively studied a total of 81 patients with chronic atrial fibrillation who underwent open cardiac surgery with concomitant RF ablation between January 2007 and March 2011. Fifty-eight patients received bipolar RF ablation and 23 received monopolar RF ablation, respectively. The sinus rhythm restoration rate, the procedural duration, the ...
Huang Jinhua J Department of Dermatology, Third Xiangya Hospital, Central South University, Changsha 410013, PR - - 2014
The aim of this study was to investigate the effectiveness of CO2 laser vaporation and topical PDT combination on condylomata acuminate (CA) located in the perianal and external genital area. A total of 119 patients (perianal CA=52 cases and external genital CA=67 cases) with at least one CA lesion>2mm were ...
Pini Rodolfo R Vascular Surgery, University of Bologna, Policlinico S. Orsola-Malpighi, via Massarenti 9, 40138 Bologna, Italy. Electronic address: - - 2014
The best strategy in the treatment for ruptured aortic aneurysm (RAAA) is an ongoing matter of debate. Differently from several retrospective studies, recent randomized controlled trials (RCTs) failed to demonstrate the superiority of endovascular repair (EVAR) over open repair (OPEN). The aim of the present study is to compare 30-day ...
Clotet Bonaventura B IrsiCaixa, Hospital Universitari "Germans Trias i Pujol", Badalona, UAB, Universitat de Vic, Catalonia, Spain. Electronic address: - - 2014
Dolutegravir has been shown to be non-inferior to an integrase inhibitor and superior to a non-nucleoside reverse transcriptase inhibitor (NNRTI). In FLAMINGO, we compared dolutegravir with darunavir plus ritonavir in individuals naive for antiretroviral therapy. In this multicentre, open-label, phase 3b, non-inferiority study, HIV-1-infected antiretroviral therapy-naive adults with HIV-1 RNA ...
Walter Veronika - - 2014
A 48 year old patient with dilated cardiomyopathy and chronic acne inversa underwent implantation of a LVAD system (Heartmate II, Thoratec, USA) March 2011. During 2011 and 2012 the patient was repeatedly readmitted for treatment of driveline infection with MRSA. Colonization was controlled with Linezolid and Rifampicin however reoccurred after ...
Manfredini Fabio - - 2014
Intermittent pneumatic compression (IPC) improves haemodynamics in peripheral arterial disease (PAD), but its effects on foot perfusion were scarcely studied. In severe PAD patients we measured the foot oxygenation changes evoked by a novel intermittent IPC device (GP), haemodynamics and compliance to the treatment. Reference values were obtained by a ...
Schneider A A Department of Surgical Oncology, Centre Paul Strauss, Strasbourg, France, - - 2014
To study the impact of thyroid surgery on obstructive sleep apnea syndrome (OSAS) evaluated by the apnea/hypopnea index (AHI) was studied. Secondary objectives were to evaluate the impact on the positional component of OSAS and to highlight possible predictors of improvement of OSAS after thyroidectomy. Twenty-eight patients with OSAS are ...
Coskun Isa I Department of Cardiovascular Surgery, Baskent University Faculty of Medicine, Dadaloglu mh. 39. Sk. No. 6, 01250, Adana, Turkey, - - 2014
Popliteal artery aneurysms (PAAs) can be treated successfully by surgical and endovascular methods; however, the best treatment strategy for a ruptured PAA has yet to be established. We assessed the clinical results of using saphenous vein interposition to treat ruptured PAAs in our hospital. The subjects of this study were ...
Lohmann-Jensen Rasmus - - 2014
Surgical treatment of osteoarthritis with total knee arthroplasty (TKA) usually takes place in a complete bloodless field using a tourniquet. However, doing the surgery without a tourniquet may reduce muscle damage, post-surgery pain and led to improved functional rehabilitation and mobilization.Methods/design: A prospective, blinded, parallel-group, controlled superiority trial, with balanced ...
Jiang Y-H YH Department of Urology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, - - 2014
Medical treatment is the first choice in the treatment of lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH). This retrospective study investigated the changes of measured parameters after 4-year medical therapy based on the reported quality of life index (QoL-I) in the International Prostate Symptom Score (IPSS) ...
Lequin Michiel B MB Neurosurgical Center Amsterdam, Neurosurgery Spine Clinic, Sint Lucas Andreas Hospital, and Academic Medical Center, Amsterdam, The - - 2014
Object Patients with recurrent sciatica due to repeated reherniation of the intervertebral disc carry a poor prognosis for recovery and create a large burden on society. There is no consensus about the best treatment for this patient group. The goal of this study was to evaluate the 12-month results of ...
Masopust Vaclav V Department of Neurosurgery, 1st Faculty of Medicine, Charles University and Central Military Hospital, Prague, Czech - - 2014
Objectives In the past 10 years, endoscopic resection of pituitary adenomas has become an alternative to microsurgical resection with the additional advantage of increasing the patient's postoperative comfort. This analysis explored whether endoscopic resection can reduce the risk of postoperative neurohypophyseal dysfunction. Design We rated and compared the need to administer desmopressin ...
Ayestaray Benoit B Department of Plastic and Reconstructive Surgery, Sud Francilien Hospital, University Paris Sud XI, Evry, - - 2014
Background Nowadays, lymphaticovenular anastomosis has been recognized as an efficient microsurgical treatment for peripheral lymphedema. The technique based on two end-to-side anastomosis is named π-shaped lymphaticovenular anastomosis. This is the venous flow-sparing technique, in which the distal endothelial cells are not sacrificed. The purpose of this study is to evaluate the ...
Compagno Nicolo' N Padua University, Clinical Immunology and Hematology, - - 2014
Intravenous immunoglobulin replacement therapy represents the standard treatment for hypogammaglobulinemia secondary to B-cell lymphoproliferative disorders. Subcutaneous immunoglobulin infusion is an effective, safe and well-tolerated treatment approach in primary immunodeficiencies but no extensive data are available on their use in secondary hypogammaglobulinemia, a frequent phenomenon occurring after treatment with anti-CD20 monoclonal ...
Mitropoulos Panagiotis G PG 2nd Eye Clinic, "Ophthalmiatrion Athinon" Specialized Eye Hospital , Athens , - - 2014
Abstract Purpose: The purpose of our study was to evaluate the potential efficacy and safety of intravitreal ranibizumab in patients with pseudophakic cystoid macular edema (CME). Methods: This retrospective study comprised 7 eyes with CME treated with intravitreal ranibizumab. Patients were examined at 1 week and 1 month after injection ...
Tosun Aliye A aClinics of Physical Medicine and Rehabilitation, Ankara Atatürk Education and Research Hospital bDepartment of Physical Medicine and Rehabilitation cDepartment of Cardiology, Kırıkkale University Faculty of Medicine dClinics of Radiodiagnostics, Ankara Atatürk Education and Research Hospital, Ankara, - - 2014
Anticoagulant drugs are used to reduce the incidence of thromboembolic events in patients at risk. However, minor and major bleeding complications may occur during anticoagulation therapy. Femoral neuropathy secondary to retroperitoneal hematoma is a well known complication of anticoagulant drugs. However, treatment of these patients is still controversial, both conservative ...
Chao Samuel T ST Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio; Rose Ella Burkhardt Brain Tumor and Neuro-oncology Center, Cleveland Clinic, Cleveland, Ohio. Electronic address: - - 2014
To review the impact of a workflow enhancement (WE) team in reducing treatment errors that reach patients within radiation oncology. It was determined that flaws in our workflow and processes resulted in errors reaching the patient. The process improvement team (PIT) was developed in 2010 to reduce errors and was ...
Capa-Grasa A A Department of Physical and Rehabilitation Medicine, University Hospital La Paz, Madrid, - - 2014
Authors have reported better outcomes, by reducing surgical dissection for carpal tunnel syndromes requiring surgery. Recently, a new sonographically guided technique for ultra minimally invasive (Ultra-MIS) carpal tunnel release (CTR) through 1mm incision has been described. We hypothesized that a clinical trial for comparing Ultra-MIS versus Mini-open Carpal Tunnel Release ...
Simader Christian C Vienna Reading Center, Department of Ophthalmology, Medical University of Vienna, Vienna, - - 2014
To identify the effects of anti-angiogenic therapy in neovascular age-related macular degeneration (AMD) in respect to morphologic type and time course and to identify prognostic factors for visual outcome on the basis of standardized optical coherence tomography (OCT) analysis. Subanalysis of a prospective, 12-month, multicenter, phase IIIb trial (Efficacy and ...
Souder Christopher D CD Department of Orthopedic Surgery, Rady Children's Hospital-San Diego, San Diego, - - 2014
Slipped capital femoral epiphysis (SCFE) can be treated by a variety of methods with the traditional method of in situ pin fixation being most commonly used. More recently, the Modified Dunn (Mod. Dunn) procedure consisting of capital realignment has been popularized as a treatment method for SCFE, particularly for more ...
Terry Michael J MJ From the *Department of Surgery, Section of Plastic and Reconstructive Surgery, Yale University School of Medicine, New Haven, - - 2014
Various surgical treatment modalities have been advocated for the treatment of Dupuytren's disease. However, recurrence following surgical treatment of Dupuytren's disease remains a common problem. Previous studies have demonstrated lower recurrence rates with use of a full-thickness skin graft. We therefore postulated that use of acellular dermal matrix may be ...
Clare S S Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, - - 2014
Long-duration beta-lactam antibiotics are used for empirical treatment in female dogs with uncomplicated bacterial cystitis. However, women with bacterial cystitis are treated with short-duration potentiated sulfonamides because longer courses of beta-lactams result in lower cure and higher recurrence rates. Short-duration potentiated sulfonamide treatment is more efficacious than long-duration beta-lactam treatment ...
Naeem Muhammad M , B-8, Akbar Apartments, Bleak House Road, Civil Lines, Cantt. Karachi, Karachi, 74200, Pakistan, - - 2014
Despite the common occurrence of ankle sprains, no treatment is considered to be the gold standard for the management of such sprains. We assessed functional treatment versus plaster of Paris (POP) for the treatment of lateral ankle sprains, with pain and function employed as the outcome measures. 126 Patients were ...
Altschul David D Center for Endovascular Surgery, Hyman-Newman Institute for Neurology and Neurosurgery, Suite 10G, Mount Sinai-Roosevelt Hospital, 1000 Tenth Ave., New York, NY, 10019, USA, - - 2014
The treatment of deep-seeded pediatric brain arteriovenous malformations (AVMs) remains a challenging task. We describe our experience using a new detachable tip microcatheter in the embolization of brain arteriovenous malformations, pial arteriovenous fistulas, and vein of Galen malformations. We describe the safety and efficacy using a new detachable tip microcatheter ...
Sheppard John D JD Ophthalmology, Eastern Virginia Medical School, Virginia Eye Consultants, 241 Corporate Boulevard, Norfolk, Virginia, 23502, United - - 2014
Introduction: Endogenous anterior uveitis, when untreated, may lead to vision loss. This study compared the safety and efficacy of difluprednate with prednisolone acetate for the treatment of this condition. Methods: This Phase III, double-masked, non-inferiority study randomized patients with mild-to-moderate endogenous anterior uveitis to receive difluprednate 0.05% (n=56) four times ...
Kohashi Keiichi K Department of Internal Medicine and Cardiology, Tama-Nagayama Hospital, Nippon Medical - - 2014
Aims: The effects of eicosapentaenoic acid (EPA) on the levels of inflammatory markers, cardiac function and long-term prognosis in chronic heart failure (CHF) patients with dyslipidemia remain unclear. Methods: A total of 139 CHF patients with a mean left ventricular ejection fraction (LVEF) of 37.6± 8.0% were divided into two ...
Salgado Christopher J CJ DeWitt Daughtry Family Department of Surgery, Division of Plastic, Aesthetic and Reconstructive Surgery, University of Miami Miller School of Medicine, - - 2014
Background:Silicone injection can cause numerous posttreatment complications-including debilitating pain, cellulitis, abscesses, overlying skin compromise, and siliconomas distorting overlying tissues-that can be difficult to manage.Objectives:The authors evaluate liposuction as a treatment for patients experiencing complications from silicone injections to the gluteal region, to both preserve aesthetic appearance and minimize further risk ...
Fedoriw Wasyl W WW Houston Methodist Orthopedics and Sports Medicine, Houston Methodist Hospital, Houston, Texas, - - 2014
BACKGROUND:The published return-to-play (RTP) rates for athletes who have undergone surgical repair of superior labrum anterior-posterior (SLAP) tears vary widely and are generally accepted to be lower in the subset of competitive throwers. The efficacy of nonsurgical treatment for this group is unknown. HYPOTHESIS:Nonsurgical treatment of SLAP tears in professional ...
Seeger J B JB Department of Orthopaedics and Orthopaedic Surgery, University Hospital Giessen and Marburg (UKGM), Klinikstraße 33, 35392, Giessen, Germany, - - 2014
Patients with lateral osteoarthritis of the knee suffer not only from pain but also impaired gait and limited mobility. Common treatment options are total knee replacement and lateral unicompartmental knee arthroplasty (UKA). The domed lateral mobile-bearing Oxford Uni is a new treatment option for patients with isolated osteoarthritis of the ...
Li Mao-Qin MQ Department of Intensive Care, Xuzhou Central Hospital, Xuzhou Hospital Affiliated to School of Medicine, Southeast University, 199 Jie Fang Road Xuzhou, Jiangsu, China, - - 2014
The aim of this study is to investigate whether hemodiafiltration combined with resin-mediated absorption is a better therapy for hyperlipidemic acute pancreatitis. Patients (n = 67) with acute pancreatitis treated in ICU from January 2009 to December 2012 were included in this study. Seven of these 67 cases were diagnosed hyperlipidemic acute ...
Toyama Keiichi K Department of Rehabilitation, Kirishima Rehabilitation Center of Kagoshima University - - 2014
The purpose of this study was to compare the effects of a novel neuromuscular electrical stimulation (NMES) to the effects of conventional treatment in patients with dysphagia after brain injury. In total, 26 patients were non-randomly divided into an experimental group (n = 12) and a control group (n = ...
Wei Yong Y Department of Nephrology, Qianfoshan Hospital, Shandong University, Jinan, - - 2014
This short-term study assessed the efficacy and safety of calcium carbonate combined with calcitonin in the treatment of hypercalcemia in hemodialysis patients. Patients (n = 64) on hemodialysis for chronic kidney disease for more than 6 months were included based on total serum calcium more than 10.5 mg/dL. All patients were randomized (1 : 1) ...
Alexander M D MD From the Department of Radiology, Santa Clara Valley Medical Center, San Jose, California (M.D.A.); Departments of Neurointerventional Surgery (P.M.M.) and Pathology (S.S.), Columbia University, New York, New York; Department of Neurology, California Pacific Medical Center, San Francisco, California (J.D.E.); Department of Medicine, St Luke's-Roosevelt Hospital, New York, New York (T.R.S.); Departments of Neurology (W.S.S.), Radiology and Biomedical Imaging (V.V.H., R.T.H., C.F.D., D.L.C., S.W.H.), and Neurological Surgery (V.V.H., R.T.H., C.F.D.), University of California, San Francisco, - - 2014
Different types of symptomatic intracranial stenosis may respond differently to interventional therapy. We investigated symptomatic and pathophysiologic factors that may influence clinical outcomes of patients with intracranial atherosclerotic disease who were treated with stents. A retrospective analysis was performed of patients treated with stents for intracranial atherosclerosis at 4 centers. ...
Johnson Jeremy L JL The University of Oklahoma College of Pharmacy, Tulsa, OK, - - 2014
It is important to prevent or slow the progression of prediabetes to type 2 diabetes and, therefore, reduce the risk of long-term complications. New therapeutic options will allow more patients to be effectively managed. Although theorized to be effective for prediabetes, dipeptidyl peptidase-4 (DPP-4) inhibitors have not been studied in ...
Steinhoff Bernhard J BJ Epilepsiezentrum Kork, Kehl, Kork, Germany. Electronic address: - - 2014
Perampanel (PER) has been approved by the European Medicines Agency (EMA) for adjunctive treatment of patients with partial-onset seizures from age 12 years on. It has been introduced to the market in Germany and Austria in 2012. This cross-sectional observational study summarizes the clinical experience of nine centers with adjunctive ...
Gönüldaş Burhanettin B Hacettepe University Faculty of Medicine, Department of Otolaryngology - Head & Neck Surgery, Ankara, - - 2014
The aim of this study is to evaluate otolaryngologic problems (upper airway obstruction, obstructive sleep apnea, restriction of mouth opening, middle ear effusion, hearing and breathing problems) and their treatments on mucopolysaccharidoses (MPS) patients and to investigate accumulation of glucosaminoglycans (GAG) in the upper airway biochemically and pathologically. 76 MPS ...
Phoa K Nadine KN Department of Gastroenterology, Academic Medical Center, University of Amsterdam, Amsterdam, the - - 2014
Barrett esophagus containing low-grade dysplasia is associated with an increased risk of developing esophageal adenocarcinoma, a cancer with a rapidly increasing incidence in the western world. To investigate whether endoscopic radiofrequency ablation could decrease the rate of neoplastic progression. Multicenter randomized clinical trial that enrolled 136 patients with a confirmed ...
Ott Oliver J OJ Dept. of Radiation Oncology, University Hospital Erlangen, Universitätsstraße 27, 91054, Erlangen, Germany, - - 2014
The goal of this work was to evaluate the long-term efficacy of two dose-fractionation schedules for radiotherapy of calcaneodynia. Between February 2006 and February 2010, 457 evaluable patients were recruited for this prospective trial. All patients received orthovoltage radiotherapy. One course consisted of 6 fractions/3 weeks. In case of insufficient remission of pain ...
Mawet Marie M * Uteron Pharma Sprl, Grace-Hollogne , - - 2014
Objective To evaluate a new levonorgestrel-releasing intrauterine system (LNG-IUS) called Levosert(®) for the treatment of heavy menstrual bleeding (HMB) in comparison to the reference product Mirena(®). Methods A multicentre, randomised, controlled trial, in non-menopausal women diagnosed with functional HMB (defined as menstrual blood loss [MBL] ≥ 80 mL) randomised to ...
Shear N H NH University of Toronto and Sunnybrook Health Sciences Centre, Toronto, - - 2014
TNF-α inhibitors, including infliximab (IFX), can improve disease control of plaque-type psoriasis. The Real-World Assessment of Long-Term Infliximab Therapy for Psoriasis (REALITY) study evaluated efficacy and safety of maintenance IFX in typical clinical settings. In this prospective, observational, open-label, multicentre study in patients with plaque-type psoriasis, IFX 5 mg/kg was ...
van Rossem C C CC Department of Surgery, Tergooi Hospital, PO Box 10016, 1201 DA Hilversum, The - - 2014
Antibiotic treatment after appendicectomy for complicated appendicitis aims to reduce postoperative infections. However, available data on the duration of treatment are limited. This study compared the difference in infectious complications between two protocols, involving either 3 or 5 days of postoperative antibiotic treatment. This was an observational cohort study of all ...
Yukutake Masanobu M Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University , Hiroshima , - - 2014
Abstract Objective. We retrospectively studied the timing of radiological improvement after steroid therapy in patients with autoimmune pancreatitis (AIP). Material and methods. Patients with AIP (n = 31) received steroids followed by diagnostic imaging within 1 month. Pancreatic swelling, pancreatic and bile duct features, and apparent diffusion coefficient (ADC) were ...
Yang Xinrui X Department of Vascular Surgery, Shanghai Ninth People's Hospital Affiliated to Shanghai JiaoTong University, School of Medicine, and Vascular Center of Shanghai JiaoTong University, Shanghai, - - 2014
The objective of this study was to evaluate the outcomes of the secondary endovascular treatment (SEVT) for symptomatic recurrences in long-segment chronic total occlusion (CTO) of femoropopliteal arteries (FPAs) and to investigate the factors affecting the outcomes. Data of patients undergoing FPA stent implantation for primary, long-segment (>10 cm) CTO lesions ...
Saper Michael M Department of Osteopathic Surgical Specialties, Michigan State University, East Lansing, Michigan, U.S.A.; Mid-Michigan Orthopaedic Institute, East Lansing, Michigan, U.S.A.. Electronic address: - - 2014
To systematically review the literature and characterize the success and failure rates of arthroscopic irrigation and debridement (I & D) in the treatment of septic arthritis after anterior cruciate ligament (ACL) reconstructions. We also aimed to identify which variables affected the failure rate. Five databases (MEDLINE, Ovid, Medscape, Web of ...
Koyama Kazuya K Center for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Japan. Electronic address: - - 2014
To assess the prevalence and risk factors of recurrence of chronic pulmonary aspergillosis (CPA) after discontinuation of antifungal triazoles. We reviewed the medical records of CPA patients who achieved resolution of clinical and radiographic manifestations and stopped taking antifungal triazoles between June 2006 and June 2012 at Tokyo National Hospital. ...
Yachimski Patrick P Division of Gastroenterology, Hepatology & Nutrition, Vanderbilt University Medical Center, Nashville, TN USA. Electronic address: - - 2014
& Aims: Endoscopic intervention or pharmacologic inhibition of cyclooxygenase might be used to prevent progression of Barrett's esophagus (BE) to esophageal adenocarcinoma (EAC). We investigated whether patients with BE prefer endoscopic therapy or chemoprevention of EAC. Eighty-one subjects with nondysplastic BE were given a survey that described 2 scenarios. The ...
Jerosch Joerg J Department of Orthopedics, Trauma Surgery and Sports Medicine, Johanna Etienne Hospital, AM Hasenberg 46, 41462, Neuss, Germany, - - 2014
Humeral resurfacing arthroplasty represents an alternative option to hemiarthroplasty for treatment of cuff tear arthropathy (CTA), with the advantages as follows: suitability for relatively young and high-demand patients because of preservation of bone stock and no loss of length, less invasive surgery, shorter operation time, no risk of periprosthetic stem ...
Ramos Telmo T Department of Orthopedics, Skaraborg Hospital Skövde, 54185, Skövde, Sweden, - - 2014
The aim of this study was to compare the Ilizarov circular fixator (IL) and locked intramedullary nailing (IM). Patients with isolated tibia shaft fractures were randomly allocated to either the IL (n = 31) or IM (n = 27) method. Conventional radiographs, postoperative pain assessment, self-appraisal scores and complications were evaluated. At the clinical ...
Shabtai Lior L International Center for Limb Lengthening, Rubin Institute for Advanced Orthopedics, Sinai Hospital of Baltimore, 2401 West Belvedere Avenue, Baltimore, MD, 21215, - - 2014
Patients with congenital limb shortening can present with joint instability, soft tissue contractures, and significant leg length discrepancy. Classically, lengthening is done with external fixation, which can result in scarring, pin site infection, loss of motion, and pain. We therefore developed an alternative to this approach, a new, controllable, internal ...
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