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Solman Lea L Department of Dermatology, Great Ormond Street Hospital for Children, London, - - 2014
To assess the safety and efficacy of systemic propranolol for the treatment of complicated infantile haemangiomas. Retrospective review of case notes of paediatric patients treated with propranolol for complicated infantile haemangiomas. Tertiary care children's hospital. All paediatric patients with complicated infantile haemangiomas who commenced treatment with propranolol from July 2008 ...
Valdés Luis L Pulmonology Department, Instituto de Investigaciones Sanitarias de Santiago (IDIS), Santiago de Compostela, - - 2014
Yellow nail syndrome (YNS) can be associated with a pleural effusion (PE) but the characteristics of these patients are not well defined. We performed a systematic review across four electronic databases for studies reporting clinical findings, PE characteristics, and most effective treatment of YNS. Case descriptions and retrospective studies were ...
Persson Saga S Saga Persson, Peter Elbe, Ioannis Rouvelas, Mats Lindblad, Koshi Kumagai, Lars Lundell, Magnus Nilsson, Jon A Tsai, Division of Surgery, Karolinska Institutet and GastroCentrum, Department of Clinical Sciences, Intervention and Technology, Karolinska University Hospital Huddinge, 141 86 Stockholm, - - 2014
To investigate possible predictors for failed self-expandable metallic stent (SEMS) therapy in consecutive patients with benign esophageal perforation-rupture (EPR). All patients between 2003-2013 treated for EPR at the Karolinska University Hospital, a tertiary referral center, were studied with regard to initial management with SEMS. Patients with malignancy as an underlying ...
Qi Xing-Shun XS Xing-Shun Qi, Wei-Rong Ren, Dai-Ming Fan, Guo-Hong Han, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an 710000, Shaanxi Province, - - 2014
To evaluate the frequency of use of various treatment modalities for Budd-Chiari syndrome (BCS) in China by conducting a preliminary survey of relevant literature. All papers regarding the treatment of BCS in Chinese patients were identified by searching PubMed, Chinese Scientific and Technological Journal, and China National Knowledge Infrastructure databases. ...
Razavi Mahmood K MK Vascular and Interventional Specialists of Orange County, Heart and Vascular Center, St. Joseph Hospital, Orange, CA 92868. Electronic address: - - 2014
The need for specialty devices to improve the technical outcome of endovascular interventions is dependent on the rate of early failure in such procedures. This meta-analysis assessed procedural outcomes of such interventions to elucidate the rate of early procedural failures and the need for such specialty devices. MEDLINE and EMBASE ...
Ramirez-Castaneda Juan J Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, - - 2014
Most long-term studies of the efficacy and safety profile of botulinum toxin (BoNT) in the treatment of dystonia are limited by lack of objective assessments, relatively small sample size, or short follow-up periods. We present one of the longest follow-up studies of BoNT treatment. This is a retrospective, longitudinal study ...
Wei Hongquan H Department of Otolaryngology, First Hospital of China Medical University, Shenyang, Liaoning, China. Electronic address: - - 2014
This study was aimed at understanding the histopathologic changes that occur in the nasal mucosa of patients with perennial allergic rhinitis after high-intensity focused ultrasound (HIFU) treatment. Biopsy specimens of the inferior turbinate mucosa were taken from 11 PAR patients before, immediately after and 1 y after HIFU treatment. Morphometric ...
Gioacchini F M FM Otolaryngology Department, University Hospital of Modena, Modena, Italy. Electronic address: - - 2014
The aim of the present review was to analyze the main clinical signs and symptoms observed in patients with thyroglossal duct cysts (TGDCs). Secondarily we investigated the outcomes following the different types of treatment of TGDCs in children and adults. Three selected strings were run on the PubMed database to ...
Spiegl Ulrich J UJ Steadman Philippon Research Institute, Vail, Colorado, - - 2014
The purposes of this study were (1) to construct a theoretical Markov decision model to compare the total remaining quality-adjusted life-years following either arthroscopic management (AM) or total shoulder arthroplasty (TSA) for the treatment of glenohumeral osteoarthritis and (2) to determine the possible effects of age on the preferred treatment ...
Alvares Ronaldo Alvarenga - - 2014
We have observed different clinical responses to botulinum toxin A (BTX-A) in patients who had similar urodynamic parameters before the procedure. Furthermore, some bladders evaluated by cystography and cystoscopy during the procedure had different characteristics that could influence the outcome of the treatment. The aim of this study was to ...
Bartorelli Antonio L AL Centro Cardiologico Monzino, Department of Clinical Sciences and Community Health, Cardiovascular Section, University of Milan, - - 2014
Objectives. To characterize the treatment of complex bifurcation lesions (BL) with the Tryton Bifurcation Stent (TBS) paired with an everolimus-eluting stent (EES). Background. Complex BL are associated with higher procedural complications and poorer long-term outcomes. The TBS is a dedicated side-branch (SB) stent designed to be used in conjunction with ...
Chung Jae Ho JH Departments of *Otolaryngology-Head and Neck Surgery and †Neurology, School of Medicine, Hanyang University, Seoul, - - 2014
To investigate adjuvant effect and safety of intratympanic steroid for the treatment of Bell's palsy. Prospective, investigator blinded, randomized study. Tertiary referral center. Patients who received treatment for Bell's palsy from December 2007 to March 2011 were randomly divided into two groups. The control group (n = 17) was treated ...
Fulton Zachary Z *University of New Mexico School of Medicine †Department of Orthopedics, University of New Mexico ‡Department of Orthopedics, Division of Pediatric Orthopaedics, University of New Mexico, UNM Carrie Tingley Hospital, Albuquerque, - - 2014
Talipes equinovarus is the most common congenital lower limb abnormality. Decreased calf size has been found to have negative impacts on patients' subjective appraisals of long-term outcomes. This study compares calf circumference ratios in 2 groups of patients with unilateral clubfoot, those treated according to the Ponseti method and those ...
Johnson Bobby L BL 3rd Department of Surgery, Division of Colorectal Surgery, College of Medicine, University of Cincinnati, Cincinnati, OH, - - 2014
Sacral neuromodulation (SNM) was approved by the FDA for the treatment of fecal incontinence (FI) in 2011, and previous industry-sponsored trials have shown excellent clinical outcomes. The purpose of this study is to examine clinical outcomes of patients treated during our initial experience with SNM. A prospective database of patients ...
Mathiesen O O Section of Acute Pain Management, Rigshospitalet, Copenhagen University Hospital, Copenhagen, - - 2014
Post-operative pain affects millions of patients worldwide and the post-operative period has high rates of morbidity and mortality. Some of this morbidity may be related to analgesics. The aim of this review was to provide an update of current knowledge of adverse events (AE) associated with the most common perioperative ...
Clinton Rebecca R Texas Scottish Rite Hospital for Children, Dallas, - - 2014
The purpose of this study is to evaluate all cases of tibial deficiency seen at a single institution from 1975 to 2012, to classify these cases by the Jones classification if possible, to evaluate for associated anomalies, and to review the surgical treatments provided to these patients. Ninety-five patients (125 ...
Lee Hun H The Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, 50 Yonseiro, Seodaemun-gu, Seoul, 120-752, South - - 2014
To assess tear cytokine levels and clinical outcomes in moderate and severe meibomian gland dysfunction (MGD) after 2 months of treatment with topical loteprednol etabonate and eyelid scrubs with warm compresses versus eyelid scrubs with warm compresses alone. Randomized controlled trial METHODS: Patients with moderate and severe MGD were randomized ...
Passero Bindu A BA Department of Pharmacy and Department of Apheresis, Albany Medical Center, Albany, New - - 2014
There is a paucity of medical literature regarding the efficacy of lock solutions in preventing catheter thrombosis. Traditionally, heparin has been used as the anticoagulant of choice for catheter locking, but it has many adverse effects associated with its use. Sodium citrate 4% is an attractive alternative to heparin. Our ...
Topazio Luca - - 2014
Bacillus Calmette-Guerin (BCG) is considered the most effective treatment to reduce recurrence and progression of non-muscle invasive bladder cancer (NMIBC) but can induce local side effects leading to treatment discontinuation or interruption. Aim of this exploratory study is to investigate if the sequential administration of Hyaluronic acid (HA) may reduce ...
Sohn Hyung Rae - - 2014
The durability of off-treatment virologic responses has not been fully elucidated in chronic hepatitis B (CHB) patients who have previously achieved complete virologic suppression with nucleos(t)ide analog (NA) therapy. This study aimed to assess off-treatment virologic relapse rates and to characterize the outcomes of subsequent re-treatment in CHB patients who ...
Bhayana Shaveta S Department of Ophthalmology, Government Medical College Hospital, Chandigarh, India, - - 2014
The aim of the study was to compare intravitreal bevacizumab (IVB) and posterior subtenon triamcinolone (PST) as an adjunct to laser treatment in diffuse diabetic macular edema (Diffuse DME). Prospective-randomized control trial of 30 eyes of 30 diabetic patients having Diffuse DME with maximum retinal thickness (MRT) was more than ...
Jens Sjoerd S Department of Radiology, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands, - - 2014
This study was designed to study the outcome of infrainguinal revascularization in patients with critical limb ischemia (CLI) in an institution with a preference towards endovascular intervention first in patients with poor condition, unfavourable anatomy for surgery, no venous material for bypass, and old age. A prospective, observational cohort study ...
Xu Da-Peng DP From the Departments of *Oral and Maxillofacial Surgery, China Medical University, Shenyang; and †Department of Oral and Maxillofacial Surgery, He Fei Stomatological Hospital, Hefei, PR - - 2014
The objective of this study was to investigate the therapeutic effects and safety of intralesional injection of high concentration of bleomycin A5 for huge (more than 5 cm in diameter) macrocystic lymphatic malformations (LMs) in the cervical region. Thirty-two patients with huge macrocystic LMs were treated with percutaneous injection of ...
de Sa Darren D Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, - - 2014
Hip arthroscopy is becoming a common technique for the diagnosis and treatment of ligamentum teres pathologic conditions. This systematic review aims to determine the indications/contraindications, treatments, and surgical outcomes for management of ligamentum teres injuries. We searched EMBASE, MEDLINE, and PubMed databases from 1946 to November 28, 2013 for all ...
Chan Kevin K Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON, - - 2014
We conducted a meta-analysis of randomized trials to compare delayed vs early motion therapy on function after arthroscopic rotator cuff repair. We searched 4 electronic databases (Medline, Embase, Cochrane, and Physiotherapy Evidence Database [PEDro]). The methodologic quality of the included studies was assessed, and the relevant data were extracted. Data ...
Patwardhan V R VR Division of Gastroenterology, Beth Israel Deaconess Medical Center, Boston, MA, - - 2014
The treatment of HBeAg-negative chronic hepatitis B (CHB) is considered to be open-ended, with no guidelines for treatment cessation. To evaluate biochemical and virological relapse requiring retreatment in noncirrhotic HBeAg-negative CHB in patients who stopped treatment following a period of prolonged viral suppression with nucleotides/nucleosides. We performed a single-centre retrospective ...
Brochard C C Service des Maladies de l'Appareil Digestif, CHU Pontchaillou, Université de Rennes 1, Rennes, France; Services d'Explorations Fonctionnelles Digestives, CHU Pontchaillou, Université de Rennes 1, Rennes, - - 2014
The natural history of nonfistulising perianal Crohn's disease (PCD) remains unknown. To assess the long-term outcome of anorectal strictures. All outcomes of PCD patients with anorectal stricture followed in a single unit from 2005 to 2013 were reviewed, as well as subsequent therapeutic management. Cumulative incidence of stricture healing (disappearance ...
Queille-Roussel C C Centre de Pharmacologie Clinique Appliquée à la Dermatologie, Hôpital L'Archet 2, Nice, - - 2014
Topical therapy remains the mainstay in the treatment of mild-to-moderate psoriasis vulgaris, and calcipotriol plus betamethasone dipropionate gel is a first-line treatment approved for the scalp and body.(1) This gel is preferred over the ointment formulation as it is easier and less time-consuming to apply.(2) Short-contact therapy, whereby the product ...
Zhao Hui H Intensive Care Unit, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine , Hangzhou 310016 , - - 2014
Abstract Purpose To assess the effects of hypothermia and normothermia treatments for sudden cardiac arrest (SCA) on brain injury recovery in rabbit models. Methods Cardiopulmonary resuscitation (CPR) was implemented on apnea-induced SCA rabbit models. Fifty survived rabbits were then randomly received hypothermia (n = 25, 32 -34 °C) or normothermia treatment ...
Dray Xavier X APHP Lariboisière Hospital and Sorbonne Paris Cité Paris 7 University, Paris, - - 2014
Background and study aims: The traditional endoscopic treatment for gastric antral vascular ectasia (GAVE) is argon plasma coagulation, but results are not always positive. Radiofrequency ablation (RFA) is a new endoscopic therapy that may be an attractive option for the treatment of GAVE. The aim of this study was to ...
Wiedel Anna-Paulina AP *Department of Oral and Maxillofacial Surgery, Skane University hospital, Malmö, Sweden, - - 2014
Summary OBJECTIVE : To compare the effectiveness of fixed and removable orthodontic appliances in correcting anterior crossbite with functional shift in the mixed dentition. Consecutive recruitment of 64 patients who met the following inclusion criteria: early to late mixed dentition, anterior crossbite with functional shift, moderate space deficiency in the ...
Lee Li-Wan LW Department of Dentistry, Taipei City Hospital, Renai Branch, Taipei, - - 2014
Traumatic injury often results in pulp necrosis of immature permanent incisors in children. This study compared clinical outcomes for 40 necrotic immature permanent incisors treated with calcium hydroxide [Ca(OH)2] or mineral trioxide aggregate (MTA) apexification/apexogenesis. Forty necrotic open-apex incisors from 40 children aged 6.5-10 years were divided evenly into four ...
Caliskan Eray E Department of Obstetrics and Gynecology, Kocaeli University, Kocaeli, - - 2014
The aim of this study was to demonstrate the effects of tubal surgery and antituberculosis treatments in patients with genital tuberculosis. A total of 38 infertile women who had been diagnosed with pelvic tuberculosis and who had had laparoscopy and hysteroscopy were recruited into the study. All women with female ...
Akhavan Setareh S Gynecology and Obstetrics Department, School of Medicine, Tehran University of Medical Sciences, Tehran, - - 2014
Zinc sulfate is beneficial in the treatment of epithelial warts. We conducted this study to compare the efficacy of combination therapy of oral zinc sulfate with conventional treatments in the treatment of vulvar warts. This study was a randomized controlled trial. The sample size was 42 in each group. Women ...
Hong Sang Duk SD Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 135-710, - - 2014
In this retrospective cohort study, we tried to evaluate the compliance of continuous positive airway treatment (CPAP) in the patients with or without previous surgical treatment to OSAS. Retrospective study with prospectively collected data was performed. Eighty-six consecutive OSAS patients who decided to try CPAP were enrolled, and data regarding ...
Nhama Abel - - 2014
Mozambique adopted artemisinin-based combination therapy (ACT) for the treatment of uncomplicated Plasmodium falciparum malaria in the year 2006, and since 2009 artemether-lumefantrine (AL) and artesunate-amodiaquine (ASAQ) have been proposed as alternative first-line treatments. A multicentre study was conducted in five sites across the country to assess the in vivo efficacy ...
Hashemian Farnaz F Department of Otolaryngology, Hamadan University of Medical Sciences, Hamadan, - - 2014
Chronic rhinosinusitis is a common disease which causes persisting inflammatory conditions of one or more sinuses. This study was designed to evaluate the effect of thyme honey nasal spray as an adjunctive medication on chronic rhinosinusitis after functional endoscopic sinus surgery. This was a randomized, placebo controlled, double-blind clinical study. ...
Miclotte Annelie A Dentistry, Department of Oral Health Sciences-Orthodontics, KU Leuven and Dentistry UZ Leuven, Kapucijnenvoer 7, 3000, Leuven, Belgium, - - 2014
The present study aims to compare mandibular third molar position in relation to the mandibular ramus, mandibular third molar angulation, potential impaction and nerve involvement in orthodontic treated versus untreated subjects. The sample consisted of 300 panoramic radiographs 119 males (mean age 16.9 years); 181 females (mean age 16.8 years), contrasting an ...
Ogura Yuichiro Y Department of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, - - 2014
To evaluate efficacy and safety of intravitreal aflibercept (IVT-AFL) in Japanese patients with wet age-related macular degeneration (wAMD) from the VIEW 2 trial. In this double-masked study, patients were randomised to: 0.5 mg IVT-AFL every 4 weeks (0.5q4); 2 mg IVT-AFL every 4 weeks (2q4); 2 mg IVT-AFL every 8 weeks (2q8) after 3 monthly injections; ...
Banerjee Soma S Department of Stroke Medicine, Clinical Neurosciences, Department of Interventional Radiology, Stem Cell Transplant Unit, and Department of Haematology, Imperial College Healthcare National Health Services Trust, London, United Kingdom; Departments of Surgery and Haematology, Faculty of Medicine, Imperial College London, London, United Kingdom; Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand; National Hospital for Neurology and Neurosurgery, University College London Hospitals National Health Services Foundation Trust, London, United Kingdom; Institute of Neurology, University College London, London, United Kingdom - - 2014
Treatment with CD34+ hematopoietic stem/progenitor cells has been shown to improve functional recovery in nonhuman models of ischemic stroke via promotion of angiogenesis and neurogenesis. We aimed to determine the safety and feasibility of treatment with CD34+ cells delivered intra-arterially in patients with acute ischemic stroke. This was the first ...
Liu Nannan N Department of Specific Diagnosis, General Hospital of Shenyang Military Area Command, 83 Wenhua Road, Shenhe District, Shenyang, 110016, - - 2014
The objectives of this study are to explore the clinical effects of treatment with tirofiban for high-risk non-ST-segment elevation acute coronary syndrome (NSTE ACS) during peri-operative intervention operation period and to improve the level of clinical treatment. Ninety cases of high-risk NSTE ACS patients were randomly selected from January 2011 ...
Chen Y-H YH 1] Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan [2] College of Medicine, Chang Gung University, Taoyuan, - - 2014
PurposeTo evaluate the refractive outcomes in children treated after intravitreal injection of bevacizumab (IVB) for retinopathy of prematurity (ROP).MethodsA retrospective, bi-centre study of 34 patients (64 eyes) was conducted. The patients were divided into three groups, patients received intravitreal IVB (IVB group), patients received combined IVB and laser treatment (IVB+Laser ...
Boey Gerald E GE *Both the authors are affiliated with the Arbutus Laser Centre, Vancouver, British Columbia, - - 2014
Previous clinical studies have investigated cryolipolysis for noninvasive reduction of fat in abdomens, outer thighs, flanks, and backs. This study investigated feasibility of cryolipolysis for inner thigh treatment. This pilot study evaluated a cryolipolysis flat cup vacuum applicator for treatment of inner thigh fat. A prototype vacuum applicator was used ...
Kim Yong Sang YS Center for Stem Cell and Arthritis Research, Department of Orthopaedic Surgery, Yonsei Sarang Hospital, Seoul, - - 2014
Marrow stimulation for the treatment of osteochondral lesions of the talus (OLTs) is controversial in patients with poor prognostic factors of OLTs. Currently, mesenchymal stem cells (MSCs) are expected to biologically augment the treatment of OLTs. To compare the clinical and magnetic resonance imaging (MRI) outcomes between an injection of ...
Ndoye I I Conseil national de lutte contre le Sida du Sénégal, Dakar, - - 2014
The ANRS Cohort 1215 brought together the first 400 patients receiving antiretroviral treatments through the government program for ARV treatment in Senegal. These people, infected with HIV-1, began their treatment between 1998 and 2002; they were treated with 2 NRTI + 1 PI or NNRTI. This prospective observational cohort received ...
Price Jennifer C JC Division of Gastroenterology and Hepatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, - - 2014
In 2011, the FDA approved telaprevir (TVR) and boceprevir (BOC) for use with pegylated interferon and ribavirin to treat hepatitis C virus (HCV) genotype 1. We aimed to evaluate the real-world application, tolerability, and effectiveness of TVR- and BOC-based HCV treatment in a large integrated care setting. We utilized Northern ...
Akwaa Frank F School of Medicine, University of Rochester, Rochester, New York, - - 2014
Abstract Background Venous thromboembolism (VTE) comprises both deep vein thrombosis and pulmonary embolism. VTE is a leading cause of morbidity and mortality worldwide and its increasing incidence and prevalence are a major health concern. The primary medical objective during the acute phase of VTE treatment is to prevent thrombus extension ...
Baulac Michel M Hospital Pitié-Salpêtrière, Paris, - - 2014
To investigate the long-term safety and maintenance of efficacy of monotherapy with once-daily zonisamide versus twice-daily controlled-release carbamazepine for partial seizures in adults with newly diagnosed epilepsy. Long-term, double-blind, extension study, conducted in patients completing a phase III noninferiority trial comparing zonisamide and carbamazepine monotherapy. Patients continued their randomized treatment, ...
Kleinstueck F S FS Spine Center, Schulthess Klinik, Lengghalde 2, 8008, Zurich, Switzerland, - - 2014
Few studies have examined the effectiveness of surgical treatment for adult degenerative scoliosis (ADS) using validated patient-orientated outcome instruments. This study reports patient outcomes in a large, consecutive series of patients being treated for ADS by simple decompression (D), short fusion (SF), or long fusion (LF). Our local spine surgery ...
Matsagkas Miltiadis M Department of Surgery-Vascular Surgery Unit, Medical School, University of Ioannina, Ioannina, Greece. Electronic address: - - 2014
This study evaluated and compared the midterm results of endovascular aortic aneurysm repair with the Endurant (Medtronic Inc, Santa Rosa, Calif) stent graft system in off-label use in patients with short (<10 mm) proximal aortic necks and in patients treated according to device-specific instructions for use. This was a case-control (2:1) ...
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