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Results 551 - 600 of 9849
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Marinschek Sabine S Department for General Paediatrics and Psychosomatic, Medical University of Graz, Graz, Styria, - - 2014
The Graz model of tube weaning has been internationally recognised as a successful and rapid tube weaning program. Beside the onsite treatment option, a telemedical counselling was specifically developed in 2009. This study aims to show outcomes of this newly invented treatment in a large sample of patients. Our retrospective ...
Filardo Giuseppe G II Orthopaedic and Traumatology Clinic - Biomechanics and Technology Innovation Laboratory, Rizzoli Orthopaedic Institute, Bologna, - - 2014
Chronic Achilles tendinopathy is responsible for a severe reduction in physical performance and persistent pain. There is currently a number of therapeutic options and the local administration of growth factors is an emerging treatment strategy. In particular, platelet-rich plasma (PRP) is a widely used way to provide a local regenerative ...
Cavallini A A - - - 2014
Endovenous laser treatment (EVLT) is an accepted form of axial vein ablation for symptomatic venous reflux but its role in the treatment of anterior accessory saphenous vein (AASV) has not been well characterized. The aim of this paper is to show the short--term result of EVLT with a ball--tipped fiber ...
Guarnera G G IDI--IRCCS, Rome, Italy - - - 2014
No study of strong methodology could be found to resolve the controversy of optimal treatment of distal deep venous thrombosis (DDVT). Some inconclusive evidence exists on two approaches to care: anticoagulants and compression therapy or compression therapy and duplex scanning monitoring. Different studies report propagation to popliteal vein in 8% ...
Chaudry Gulraiz G Vascular Anomalies Center, Boston Children's Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA, 02115, USA, - - 2014
Sclerotherapy is the mainstay of treatment of macrocystic lymphatic malformation (LM), but the response using traditional sclerosants is much less beneficial in microcystic lesions. Intralesional bleomycin has been reported to be effective in microcystic LM; however, its use is limited by concerns about pulmonary fibrosis. The purpose of this study ...
Rajpathak Swapnil N SN Merck & Co., Inc. Whitehouse Station, NJ. Electronic address: - - 2014
Patients with type 2 diabetes on metformin monotherapy frequently require treatment intensification with another anti-hyperglycemic medication over time. Previous studies have indicated that a high proportion of patients with diabetes have a significant delay in the initiation of oral add-on therapy after metformin alone fails to achieve targeted glycemic control. ...
Lévy Samuel S Aix-Marseille Université, 2 Place Delibes, 13008, Marseille, France, - - 2014
New oral anticoagulants (NOACs) have emerged as an alternative therapy to warfarin in the treatment of arterial and venous thromboembolism and in stroke prevention in patients with non-valvular atrial fibrillation (AF). Three of them, i.e., dabigatran, rivaroxaban, and apixaban, have been approved for clinical use in North America and in ...
Klekamp Jörg J Department of Neurosurgery, Christliches Krankenhaus, Danziger Str. 2, 49610, Quakenbrück, Germany, - - 2014
Basilar invagination is a rare craniocervical malformation which may lead to neurological deficits related to compression of brainstem and upper cervical cord as well as instability of the craniocervical junction. This study presents results of a treatment algorithm developed over a 20-year period focussing on anatomical findings, short-term and long-term ...
Laver Lior L Department of Orthopaedic Surgery, Sports Medicine Unit, "Meir" Medical Center, The Sackler School of Medicine (Tel-Aviv University), Kfar-Saba, Israel, - - 2014
Syndesmotic sprains are uncommon injuries that require prolonged recovery. The influence of ultrasound-guided injections of platelet-rich plasma (PRP) into the injured antero-inferior tibio-fibular ligaments (AITFL) in athletes on return to play (RTP) and dynamic stability was studied. Sixteen elite athletes with AITFL tears were randomized to a treatment group receiving ...
Teitelbaum Ezra N EN Department of Surgery, Northwestern University Feinberg School of Medicine, 676 North Saint Clair Street, Chicago, IL, 60611, USA, - - 2014
Peroral esophageal myotomy (POEM) is a new endoscopic operation for the treatment of achalasia. Here, we report 1-year physiologic and symptomatic outcomes following the procedure. POEM patients from a single-institution series who were more than 1 year removed from surgery were studied. Eckardt and GerdQ scores were obtained to assess symptoms. ...
Boccon-Gibod Laurent L Membre de l'Académie de Chirurgie, Expert près les Tribunaux, Paris, - - 2014
Guidelines for prostate cancer treatment suggest that intermittent androgen deprivation (IAD) can be considered for certain patients. To evaluate the efficacy and safety of degarelix as IAD for one or more treatment cycle(s) in prostate cancer patients requiring androgen deprivation. This open-label uncontrolled multicenter study included patients with prostate-specific antigen ...
Tahar Rachida R Unité Mixte de Recherche 216 Mère et Enfant Face aux Infections Tropicales, Institut de Recherche pour le Développement (IRD), Unité de formation et de recherche (UFR) de Pharmacie, 75270 Paris, France Laboratoire de Recherche sur le Paludisme, Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale (OCEAC), B.P. 288, Yaoundé, - - 2014
 Artemisinin-based combination therapies (ACTs) are recommended for the treatment of acute uncomplicated falciparum malaria in many endemic countries. Despite the emergence of artemisinin resistance, few alternative non-ACTs, including atovaquone-proguanil, are currently available.  Plasmodium falciparum-infected Cameroonian children≤5 years old (n=338) were randomized to artesunate-amodiaquine, atovaquone-proguanil, or artesunate-atovaquone-proguanil treatment groups and followed ...
Flachenecker Peter P Neurological Rehabilitation Centre Quellenhof, Bad Wildbad, - - 2014
Background: Nabiximols (Sativex®), in a cannabinoid-based oromucosal spray, is an add-on therapy option for patients with moderate to severe multiple sclerosis spasticity (MSS) resistant to other medications. The study objective was to provide long-term data on clinical outcomes, tolerability, quality of life and treatment satisfaction for MSS patients receiving nabiximols ...
Bayoumi A M AM Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia. Electronic address: - - 2014
Temporomandibular joint (TMJ) dislocation is an excessive forward movement of the condyle beyond the articular eminence with complete separation of the articular surfaces and fixation in that position. This study was conducted to assess autologous blood injection to the TMJ for the treatment of chronic recurrent TMJ dislocation. Fifteen patients ...
Fokkenrood H J P HJ Department of Vascular Surgery, Catharina Hospital, Eindhoven, The Netherlands; CAPHRI Research School, Maastricht University, Maastricht, The - - 2014
International guidelines recommend supervised exercise therapy (SET) as primary treatment for intermittent claudication (IC). The aim of this study was to calculate treatment costs in patients with IC and to estimate nationwide annual savings if a stepped care model (SCM, primary SET treatment followed by revascularization in case of SET ...
Monk Bradley J BJ Creighton University School of Medicine and University of Arizona Cancer Center at St Joseph's Hospital, Phoenix, AZ, USA. Electronic address: - - 2014
Angiogenesis is a valid target in the treatment of epithelial ovarian cancer. Trebananib inhibits the binding of angiopoietins 1 and 2 to the Tie2 receptor, and thereby inhibits angiogenesis. We aimed to assess whether the addition of trebananib to single-agent weekly paclitaxel in patients with recurrent epithelial ovarian cancer improved ...
Lohrer Heinz H Institute for Sports Medicine Frankfurt am Main , Otto-Fleck-Schneise 10, 60528, Frankfurt/Main, Germany, - - 2014
The results of operative treatment for recalcitrant midportion Achilles tendinopathy and recalcitrant retrocalcaneal bursitis were evaluated using the patient administered, disease specific, and validated VISA-A-G questionnaire. A cohort of 89 patients was prospectively followed. These patients underwent operations for sport induced midportion Achilles tendinopathy (39 procedures) or retrocalcaneal bursitis (55 ...
Dapul Geraldine G Department of Physical Medicine and Rehabilitation Oakwood, School of Medicine, Wayne State University, Dearborn, MI, - - 2014
Severe tetanus remains a serious issue in less developed countries, leading to prolonged hospitalization due to prolonged neuromuscular contraction of muscles. We present a case of severe tetanus in the United States that was successfully managed with intrathecal baclofen. A 42-year-old male without tetanus vaccination history presented to the emergency ...
Cakir Volkan V Ataturk Training and Research Hospital, Department of Radiology, Division of Ä°nterventional Radiology, Katip Celebi University, Izmir, Turkey, - - 2014
The purpose of this study was to compare the efficacy of percutaneous aspiration thrombectomy (PAT) followed by standard anticoagulant therapy, with anticoagulation therapy alone, for the treatment of acute proximal lower extremity deep vein thrombosis. In this randomised, prospective study, 42 patients with acute proximal iliofemoral deep vein thrombosis documented ...
Neggers S J C M M SJ Department of Medicine, Endocrinology section, Pituitary Center Rotterdam, Erasmus University Medical Center Rotterdam, the - - 2014
Background: Treatment for acromegaly patients with long-acting somatostatin receptor ligands (LA-SRIFs) does often not result in complete normalization of insulin-like growth factor 1 (IGF-I). Addition of pegvisomant, a growth hormone receptor antagonist (PEGV), could improve this, however the literature has not described long-term follow-up. Objective: To assess long-term efficacy and ...
Mavropoulou Antonia A Department of Veterinary Sciences, University of Parma, Via del Taglio 10, Parma 43126, - - 2014
This study shows that a combination of doxycycline (10mg/kg/sid for 30 days) and ivermectin (6μg/kg/every 15 days for 6 months) is well tolerated for the treatment of canine heartworm disease (HWD). Monthly echocardiography showed that 84% of treated dogs either progressively improved parameters indicative of pulmonary hypertension or, following slight ...
Takeuchi Masaru M Department of Ophthalmology, National Defense Medical College, Tokorozawa, Japan. Electronic address: - - 2014
To evaluate the long-term efficacy and safety of infliximab for the treatment of uveitis in Behçet's disease (BD). Retrospective multicenter study using a questionnaire. A total of 164 consecutive patients with BD treated with infliximab for more than 1 year were studied. The mean age at initiation of infliximab treatment ...
Li Julius J South Texas Veterans Health Care System, San Antonio, TX, USA The University of Texas at Austin College of Pharmacy, Austin, TX, USA Pharmacotherapy Education and Research Center, University of Texas Health Sciences Center San Antonio, San Antonio, TX, USA - - 2014
Contrary to prior case reports describing occasional clinical failures with cefazolin for methicillin-susceptible Staphylococcus aureus (MSSA) infections, recent studies demonstrated no difference in outcomes between cefazolin and antistaphylococcal penicillins for the treatment of MSSA bacteremia. While promising, these studies had low frequencies of high inoculum infections, such as endocarditis. This ...
Foucrier Arnaud A From the *Department of Anesthesiology and Critical Care, University Pierre et Marie-Curie-Paris 6, Assistance Publique-Hôpitaux de Paris, Paris, France; †Hospital Pitié-Salpétrière, Paris, France; ‡Department of Anaesthesia, Perioperative Research Group, University of KwaZulu-Natal, Pietermarizburg, South Africa; §The Perioperative Research Group, Population Health Research Institute, Hamilton, Ontario, Canada; ‖Biostatistical and Clinical Epidemiology Department, Faculty of Medicine, Nimes University Hospital, Montpellier 1 University, Montpellier, France; and ¶Departments of Anesthesia & Clinical Epidemiology and Biostatistics, Michael DeGroote School of Medicine, Faculty of Health Sciences, McMaster University and Population Health Research Institute, David Braley Cardiac, Vascular and Stroke Research Institute, Perioperative Medicine and Surgical Research Unit, Hamilton, Ontario, - - 2014
Acute cardiac events are a frequent cause of morbidity after vascular surgery. The impact of early evidence-based treatment for patients with an acute cardiac event after vascular surgery on long-term postoperative outcomes has not been extensively studied. We hypothesized that providing appropriate evidence-based treatment to patients with elevated postoperative cardiac ...
Franco Matheus Cavalcante MC Matheus Cavalcante Franco, Gustavo Flores Gomes, Frank Shigeo Nakao, Gustavo Andrade de Paulo, Angelo Paulo Ferrari Jr, Ermelindo Della Libera Jr, Digestive Endoscopy Unit, Division of Gastroenterology, Federal University of São Paulo, São Paulo 04023-900, - - 2014
To evaluate the efficacy and safety of undiluted N-butyl-2 cyanoacrylate plus methacryloxysulfolane (NBCM) as a prophylactic treatment for gastric varices (GV) bleeding. This prospective study was conducted at a single tertiary-care teaching hospital between October 2009 and March 2013. Patients with portal hypertension (PH) and GV, with no active gastrointestinal ...
Moojen Dirk Jan F DJ Department of Orthopaedic Surgery and Traumatology , Joint Research, Onze Lieve Vrouwe Gasthuis , - - 2014
Background - Treatment of an acute total hip arthroplasty (THA) infection aims at control of the infection with retention of the implant by surgical debridement and antibiotic treatment. There is no clear evidence whether a single surgical debridement is sufficient or whether multiple procedures are necessary for optimal treatment. Methods ...
Turgutalp Kenan K Department of Internal Medicine, Division of Nephrology, Mersin University , Mersin , Turkey - - 2014
Abstract Background: Novel biomarkers are needed to predict the response to treatment in patients with nephrotic syndrome (NS) due to primary glomerulonephritides (PGN). We aimed to test the predictive value of red blood cell distribution width (RDW) for estimation of response to therapy in adult patients with NS. Study design, ...
Tawfik Abeer Attia AA Dermatology Unit, Department of Medical Applications of Lasers, National Institute of Laser Enhanced Sciences, Cairo University, Giza, - - 2014
Pulsed dye laser has been used successfully in the treatment of nail psoriasis. Intense pulsed light (IPL) has been used in the treatment of plaque psoriasis using a 550-nm filter. To study the efficacy of IPL in the treatment of nail psoriasis. Twenty patients with finger and toe nail psoriasis ...
Ridderstråle Martin M Steno Diabetes Center, Gentofte, Denmark. Electronic address: - - 2014
Metformin is the recommended first-line pharmacotherapy for patients with type 2 diabetes. There is no consensus on the optimum second-line pharmacotherapy. We compared the efficacy and safety of the sodium glucose cotransporter 2 inhibitor empagliflozin and the sulfonylurea glimepiride as add-on to metformin in patients with type 2 diabetes. In ...
Tsze Daniel S DS Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, New York - - 2014
We present the case of a 3-month-old girl who had unrepaired Tetralogy of Fallot who presented to the emergency department with an acute hypoxic episode. The patient was hyperpneic and cyanotic, with an initial oxygen saturation of 56%. She did not respond to knee-to-chest positioning. A single dose of intranasal ...
Yang Rong R The affiliated drum tower hospital of Nanjin University, school of medicine, Urology, Nanjing, Jiangsu, China ; - - 2014
Purpose: To analyze the feasibility, safety and therapeutic effects of retroperitoneoscopic-guided cool-tip radiofrequency ablation (RCRFA) used for the treatment of adrenocortical aldosteronoma. Patients and methods: We performed a retrospective comparasion of RCRFA (n=12) and laparoscopic partial adrenalectomy (LPA) (n=26) in the patients with solitary aldosterone-producing adenoma in our center from ...
Rintoul Robert C RC Department of Thoracic Oncology, Papworth Hospital, Cambridge, - - 2014
Malignant pleural mesothelioma incidence continues to rise, with few available evidence-based therapeutic options. Results of previous non-randomised studies suggested that video-assisted thoracoscopic partial pleurectomy (VAT-PP) might improve symptom control and survival. We aimed to compare efficacy in terms of overall survival, and cost, of VAT-PP and talc pleurodesis in patients ...
Nutman Amir A Division of Epidemiology, Tel Aviv- Sourasky Medical Center, Tel-Aviv, - - 2014
Carbapenem-resistant Acinetobacter baumannii (CRAB) is an increasingly common nosocomial pathogen. We sought to identify clinical and microbiological predictors of 14-day mortality among patients with CRAB bacteremia. This case-control study included all adult patients in one Israeli hospital with CRAB on blood culture between July 2008 and June 2011. Cases were ...
Hayashi Nobukazu N Department of Dermatology, Toranomon Hospital, Tokyo, - - 2014
The efficacy of adapalene for acne treatment has been established. However, because of local adverse reactions, a fair number of patients discontinue adapalene treatment before experiencing its effects. To examine the usefulness of moisturizers concomitant with adapalene on adherence to treatment and its therapeutic effects in patients, 100 patients with ...
Wang Tang-Chuan TC Department of Otolaryngology, China Medical University Hospital, Taichung, - - 2014
The purpose of the study was to perform a systematic review and meta-analysis of the literature to compare the efficacy (and other postoperative outcomes) of nonabsorbable versus absorbable nasal packing after functional endoscopic sinus surgery (FESS) for the treatment of chronic rhinosinusitis. Studies were considered for inclusion if they were ...
Nappi Rossella E RE * Research Center for Reproductive Medicine, IRCCS Policlinico San Matteo Foundation, University of Pavia , Pavia , - - 2014
Objectives To evaluate the impact of a 91-day extended regimen combined oral contraceptive (150 μg levonorgestrel [LNG]/30 μg ethinylestradiol [EE] for 84 days, followed by 10 μg EE for seven days [Treatment 1]) compared with two traditional 21/7 regimens (21 days 150 μg LNG/30 μg EE [Treatment 2] or 150 ...
Alobaid Adel S AS New York University College of Dentistry, New York, New - - 2014
This retrospective cohort study compared clinical and radiographic outcomes of endodontic treatment performed in immature nonvital permanent teeth by apexification (calcium hydroxide or apical barrier with mineral trioxide aggregate) versus revascularization. A comprehensive chart review was performed to obtain a cohort of previously completed cases with recalls. Clinical and radiographic ...
Vicari Enzo - - 2014
This study was undertaken to evaluate the influence of treatment with rifaximin followed by the probiotic VSL#3 versus no treatment on the progression of chronic prostatitis toward chronic microbial prostate-vesiculitis (PV) or prostate-vesiculo-epididymitis (PVE). A total of 106 selected infertile male patients with bacteriologically cured chronic bacterial prostatitis (CBP) and ...
Roussin A A Internal and Vascular Medicine, Centre Hospitalier de l'Université de Montréal, Montreal, Canada - - - 2014
Deep vein thrombosis (DVT) is a manifestation of venous thromboembolism (VTE) and accounts for most venous thromboembolic events. Although DVT is not directly lifethreatening, thrombi in the proximal veins of the leg can embolize to the lungs to form a pulmonary embolism, which may prove rapidly fatal. If untreated, DVT ...
Wang Yu-Chi YC Department of Neurosurgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University, Taoyuan, Taiwan, - - 2014
Background: Arteriovenous malformation (AVM) is one of the cerebrovascular diseases that bear a high risk of hemorrhage. The treatment modalities include microsurgical resection, endovascular embolization, stereotactic radiosurgery, or combinations that vary widely. Several large series have been reported, while data from Asian populations were few. The aim of this study ...
Shiraishi Manabu M Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma, Omiya-Ku, Saitama, 330-8503, Japan, - - 2014
Waffle procedure, a small grid-like incision of epicardium, is a surgical technique for constrictive pericarditis with epicardial thickening. Yet evidences to endorse this approach for improved outcomes are lacking. The aim of this study is to elucidate better surgical treatment strategy for constrictive pericarditis with epicardial thickening. Twenty-five patients (mean ...
Tuppin Philippe - - 2014
This very large population-based study investigated outcomes after a diagnosis of prostate cancer (PCa) in terms of mortality rates, treatments and adverse effects. Among the 11 million men aged 40 years and over covered by the general national health insurance scheme, those with newly managed PCa in 2009 were followed ...
Anzidei Michele M From the Departments of *Radiological, Oncological and Pathological Sciences, and †Surgery and Transplantation "P. Stefanini," Policlinico Umberto I, Sapienza University of Rome, Rome, - - 2014
The purpose of this study was to evaluate the feasibility of magnetic resonance-guided focused ultrasound (MRgFUS) ablation for pain palliation and local tumor control in selected patients with unresectable primary pancreatic adenocarcinoma. After providing dedicated informed consent, 7 patients with histologically proven unresectable pancreatic adenocarcinoma underwent MRgFUS treatment on a ...
Cunha-Vaz José J Association for Innovation and Biomedical Research on Light and Image, Coimbra, Portugal. Electronic address: - - 2014
To present the safety and efficacy of intravitreal implants releasing 0.2 μg/day fluocinolone acetonide (FAc) in patients with chronic versus nonchronic diabetic macular edema (DME). To assess ocular characteristics, anatomic changes, and re-treatment and ancillary therapies that may explain the differential treatment effect seen with intravitreal implants releasing FAc 0.2 ...
Hobi S S Stefan Hobi, Medizinische Kleintierklinik, Ludwig-Maximilians-Universität, Veterinärstraße 13, 80539 München, Germany, Email: - - 2014
Objectives: Canine atopic dermatitis is a very common disease in small animal practice. Its only specific treatment is allergen immunotherapy. In rush-immunotherapy (RIT) increasing doses of allergen extract are injected subcutaneously in short intervals. Maintenance doses are achieved within one day compared to weeks or months with conventional immunotherapy. The ...
Talab Saman Shafaat SS Department of Urology, Massachusetts General Hospital, Harvard Medical School, Boston, - - 2014
This study aimed evaluate the safety and feasibility of endoscopic potassium titanyl phosphate (KTP) laser application in the management of patients with radiation-induced hemorrhagic cystitis (RHC). We retrospectively reviewed the records of 20 patients with RHC who underwent endoscopic KTP laser ablation of telangiectatic bladder vessels between October 2005 and ...
McNab Alan A AA *Orbital Plastic and Lacrimal Clinic, Royal Victorian Eye and Ear Hospital, †Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, University of Melbourne, Melbourne, Australia; ‡South Australian Institute of Ophthalmology, University of Adelaide, Adelaide, Australia; and §Royal North Shore Hospital, Sydney, - - 2014
Orbital cavernous hemangiomas (OCH) often present as incidentally found asymptomatic lesions, and it has been reported that such lesions do not grow. The authors' own experience has been different. They describe the natural history of OCH in a cohort with asymptomatic incidentally found lesions and compare them with patients with ...
El Zawahry Bakr B Dermatology Department, Cairo University, Giza, - - 2014
Facial freckles are a cosmetic concern to Egyptians, particularly young females. Several therapeutic lines exist with variable response rates and limitations. Fractional carbon dioxide (FCO2) laser provides minimal ablation and therefore less down time and less side effects. The efficacy and safety of this laser technology have still not been ...
Menda Shivali A SA Department of Ophthalmology, University of California San Francisco, 10 Koret Way, San Francisco, CA, 94143, - - 2014
To compare the complication rate and effectiveness of mitomycin C (MMC), Ologen alone, and Ologen with 5-fluorouracil (5-FU) as adjunctives with Ex-PRESS mini shunt for medically uncontrolled glaucoma. Retrospective comparative study of 59 Ex-PRESS mini shunt trabeculectomy operations coupled with Ologen implantation alone, transient MMC application or Ologen implantation with ...
Quéré I I EA 2992, Vascular Medicine Unit, CIC1001 Inserm, CHU de Montpellier, université Montpellier 1, 34295 cedex 5 Montpellier, France. Electronic address: - - 2014
Lymphedema treatment is based on Decongestive Lymphedema Therapy (DLT) with an intensive phase followed by a long-term maintenance phase. This study aimed to observe volume variation over the intensive phase and 6 months later. Prospective multicentre observational study of patients with unilateral lymphedema. The primary objective was to assess lymphedema ...
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