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Chi Yihebali - - 2013
Gambogic acid is a pure active compound isolated from the traditional Chinese medicinal plant gamboge (Garcinia morella Desv.). Based on the preliminary results of a phase I study, this phase IIa study compared the efficacy and safety of different dosage schedules of gambogic acid in patients with advanced malignant tumors. ...
Hjortdal Vibeke Elisabeth - - 2013
OBJECTIVES: We investigated whether open-heart surgery with the use of extracorporeal circulation has an impact on menstrual bleeding. METHODS: The menstrual bleeding pattern was registered in fertile women undergoing open-heart surgery in 2010-12. Haematocrit and 24-h postoperative bleeding were compared with those of men undergoing cardiac surgery. RESULTS: Women (n ...
Boyer Sylvie S INSERM, UMR912 (SESSTIM), Marseille, France. - - 2013
In low-income countries, the use of laboratory monitoring of patients taking antiretroviral therapy (ART) remains controversial in view of persistent resource constraints. The Stratall trial did not show that clinical monitoring alone was non-inferior to laboratory and clinical monitoring in terms of immunological recovery. We aimed to evaluate the costs ...
Vishwanathan K - - 2013
The aim of this study was to measure inter- and intra-observer agreement on the radiographic classification of scapholunate advanced collapse (SLAC) and scaphoid nonunion advanced collapse (SNAC) wrist. Radiographs of 41 patients with SLAC wrist and 47 patients with SNAC wrist were graded on two separate occasions by four orthopaedic ...
Erduran Mehmet - - 2013
PURPOSE: Vertical mattress configuration is the strongest of all other configurations and the repairing devices of meniscus repair. The purpose was whether increasing the inclination angle between two strands of the vertical mattress configuration by increasing the amount of meniscus tissue captured would enhance the initial strength of the construction. ...
Sota Teiji - - 2013
The evolution of 13- and 17-y periodical cicadas (Magicicada) is enigmatic because at any given location, up to three distinct species groups (Decim, Cassini, Decula) with synchronized life cycles are involved. Each species group is divided into one 13- and one 17-y species with the exception of the Decim group, ...
Staar S - - 2013
We assessed the effect of modifying standard Magill forceps on the laryngeal introduction of an Eschmann stylet during nasotracheal intubations with three indirect laryngoscopes (Airtraq™, C-MAC(®) or GlideScope(®) ) in patients with predicted difficult intubation. We allocated 50 participants to each laryngoscope. The stylet was advanced by one forceps followed ...
Han S H - - 2013
During fibreoptic intubation, it is often difficult to advance a tracheal tube over the fibreoptic bronchoscope. We performed a prospective randomised study to investigate the effect of the jaw-thrust manoeuvre on the ability to advance a tracheal tube during oral fibreoptic intubation. After placing the bronchoscope in the trachea, an ...
Lee Yee Han Dave - - 2013
BACKGROUND:All-inside meniscus repair eliminates the need for an extra incision and decreases neurovascular injury risk. Biomechanical testing can help delineate the efficacy of all-inside device use. HYPOTHESIS:There would be no group differences between 4 peripheral meniscus repair techniques and 3 different devices tested. STUDY DESIGN:Controlled laboratory study. METHODS:Equivalent-sized menisci with ...
Collado Serra Argimiro A Department of Urology, Fundación Instituto Valenciano de Oncología, Valencia, Spain. - - 2013
To evaluate the efficacy of the AdVance transobturator male sling in the treatment of male stress urinary incontinence and to identify the preoperative predictors of a successful outcome. All patients were considered for sling placement 1 year after radical prostatectomy or transurethral resection of the prostate. The degree of incontinence ...
Miranda-Filho Demócrito B - - 2013
OBJECTIVE: To estimate the incremental cost of delivering intrathecal tetanus immunoglobulin compared to an intramuscular option. METHODS: To compare the two interventions, costs were estimated using standard cost methodology. Cost categories were personnel, overhead, consumables, antibiotics to treat infection, gases for respiratory assistance and immunoglobulin. Tetanus patients, aged 12 years or ...
Huang Jiwei - - 2013
OBJECTIVE: To evaluate whether remote ischaemic preconditioning (RIPC) reduces renal injury in patients undergoing laparoscopic partial nephrectomy (LPN). PATIENTS AND METHODS: In all, 82 patients undergoing LPN were randomly assigned to either the RIPC or control group, with 40 and 38 patients, respectively completing 6-months follow-up. RIPC was conducted after ...
Wang Yingsong - - 2013
Object Phase contrast-cine MRI (PC-cine MRI) studies in patients with syringomyelia and Chiari malformation Type I (CM-I) have demonstrated abnormal CSF flow across the foramen magnum, which can revert to normal after craniocervical decompression with syrinx shrinkage. In order to investigate the mechanisms leading to postoperative syringomyelia shrinkage, the authors ...
Chan Fuan Chiang - - 2013
We have previously reported that monobloc advancement by distraction osteogenesis resulted in decreased morbidity and greater advancement with less relapse compared with acute monobloc advancement with bone grafting. In this study, we examine the three-dimensional (3D) volumetric soft-tissue changes in monobloc distraction.Patients with syndromic craniosynostosis who underwent monobloc distraction from ...
Ogata Yumi - - 2013
Purpose: The aim of this study was to evaluate the efficacy and morbidity of two periodontal releasing incision techniques in vertical ridge augmentation. Materials and Methods: Twenty-three vertical and horizontal defects (Seibert Class III) were selected to compare the double-flap incision (DFI) to the conventional periosteal releasing incision (PRI). An ...
Polyzos N P - - 2013
STUDY QUESTION: Will sequential administration of highly purified (hp)-HMG after corifollitropin alfa in a GnRH antagonist protocol benefit women with poor ovarian response according to the Bologna criteria? SUMMARY ANSWER: Corifollitropin alfa followed by hp-HMG in a GnRH antagonist protocol results in very promising pregnancy rates, albeit only in young ...
Jyoti Naresh N Assistant Professor, Department of Pharmacology, Chintpurni Medical College , Bungal, District, Pathankot, Punjab-145001, India - - 2013
A serial prescription audit in four cycles (three months each) was conducted at Jhalawar Medical College and Hospital and at Chintpurni Medical College and Hospital for two years, one year in each hospital. One cycle included the prescriptions which were collected by using a digital camera from the outdoor patients ...
Savk E E Adnan Menderes University, Department of Dermatology, Turkey. - - 2013
Adjuvant therapeutic methods are employed when pemphigus vulgaris (PV) fails to be controlled by conventional corticosteroid treatment. The efficacy of double filtration plasmapheresis (DFPP) was investigated in a PV patient with severe, refractory mucosal disease. A total of 3 DFPP cycles, each cycle consisting of 5 double filtration sessions conducted ...
De Cock Erwin - - 2013
Abstract Objective: This time-and-motion study aimed to quantify health-care personnel time associated with routine anaemia-management tasks for maintenance therapy with C.E.R.A. (continuous erythropoietin receptor activator) that treats anaemia with once-monthly injections versus other erythropoiesis -stimulating agents ("Other ESAs"), including shorter-acting ESAs (epoetin alfa, epeotin beta) and darbepoetin alfa. Methods and ...
Panagiotidis Y - - 2013
The use of open carriers for embryo vitrification has raised safety concerns and therefore vitrification in closed systems has been proposed. However, the drop in the cooling rate emerges as a major drawback. The objective of the present study was to compare the efficiency of vitrification in open versus closed ...
Khattab Ahmed A - - 2013
OBJECTIVES: We sought to evaluate the strategy success and short term clinical outcomes of direct stenting via 5 French (F) diagnostic catheters using a novel bare metal stent with integrated delivery system (Svelte Medical Systems, New Providence, New Jersey, USA) and compare the results to a conventionally treated matched group. ...
Badros A Z - - 2013
This phase 2 study assessed the safety, pharmacokinetics, pharmacodynamics, and efficacy of carfilzomib, a selective proteasome inhibitor, in patients with multiple myeloma and varying degrees of renal impairment, including patients on chronic hemodialysis. Patients were grouped by creatinine clearance: >80, 50-80, 30-49, <30 ml/min, and chronic hemodialysis. Carfilzomib was administered on ...
Paradisi Roberto - - 2013
Abstract The long-term effects and tolerability of flutamide (Flu) on the menstrual cycle and the ovulatory function of hyperandrogenic women with or without polycystic ovary syndrome (PCOS) were investigated. The study included 118 white women with the diagnosis of various forms of hyperandrogenism (80 PCOS and 38 non-PCOS patients). Patients ...
Hasegawa Kohei K Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, 326 Cambridge St, Ste 410, Boston, MA 02114, USA. - - 2013
It is unclear whether advanced airway management such as endotracheal intubation or use of supraglottic airway devices in the prehospital setting improves outcomes following out-of-hospital cardiac arrest (OHCA) compared with conventional bag-valve-mask ventilation. To test the hypothesis that prehospital advanced airway management is associated with favorable outcome after adult OHCA. ...
Dieckmann Ralf R Department of Orthopaedics and Tumor Orthopaedics, Münster University Hospital, Albert-Schweitzer-Campus 1, A1, 48149, Münster, Germany. - - 2013
The functional results after reconstruction of the proximal humerus in tumour surgery are poor. Therefore, a reversed proximal humerus replacement was developed in our institution (MUTARS humerus inverse). A low degree of wear on the polyethylene is required because of the patients' youth and demands on shoulder function. A special ...
Denost Quentin Q University Hospital Centre (CHU) Bordeaux, Haut-Lévêque Hospital, Digestive Surgery, Bordeaux, France. - - 2013
The aim of this study was to assess oncological outcomes in patients treated with pancreaticoduodenectomy for advanced pancreatic head adenocarcinoma after preoperative chemoradiotherapy and to compare these with outcomes in patients treated with surgery alone. From 2004 to 2009, patients treated with pancreaticoduodenectomy for pancreatic head adenocarcinoma were included in ...
Elmunzer B Joseph BJ Division of Gastroenterology, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA. - - 2013
A recent large-scale randomized controlled trial (RCT) demonstrated that rectal indomethacin administration is effective in addition to pancreatic stent placement (PSP) for preventing post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) in high-risk cases. We performed a post hoc analysis of this RCT to explore whether rectal indomethacin can replace PSP in ...
Wegehaupt Florian J - - 2013
Abstract Objective. To test the durability of sealants applied for prevention of erosive dentine mineral loss under erosive/abrasive conditions. Methods. Forty-eight bovine dentine samples doped with (32)P were randomly allocated to four groups (1-4). All samples performed a de- and remineralizations pre-cycling (6 × 1 min erosion in HCl: pH ...
Kellokumpu-Lehtinen Pirkko-Liisa PL Department of Oncology, Tampere University Hospital, Tampere, Finland. - - 2013
Docetaxel administered every 3 weeks is a standard treatment for castration-resistant advanced prostate cancer. We hypothesised that 2-weekly administration of docetaxel would be better tolerated than 3-weekly docetaxel in patients with castration-resistant advanced prostate cancer, and did a prospective, multicentre, randomised, phase 3 study to compare efficacy and safety. Eligible ...
Lim Tae Kang - - 2013
The aims of this study were to evaluate the incidence of anchor penetration of the far cortex of the glenoid neck after arthroscopic Bankart repair and to compare the biomechanical properties of anchors in the 4- and 5:30- to 6-o'clock positions on the glenoid. Twelve (6 matched pairs) fresh-frozen human ...
Ajayi Olukunle Adegboye - - 2013
A 20-year-old para 2 woman had a preterm delivery at 25 weeks and 6 days, readmitted to the hospital 25 days after delivery with severe secondary postpartum haemorrhage (PPH). Uncontrolled by initial conservative management, she underwent uterine curettage followed by Bakri balloon tamponade. She later had laparotomy for continued bleeding. ...
Tarniţă Daniela - - 2013
The paper presents a comparative experimental study of flexion-extension movement in normal and osteoarthritic human knee. Measurements were performed on a group of seven healthy subjects and on a group of five patients with OA knees, for which experimental data were acquired for walking cycles on treadmill. Using an electrogoniometer-based ...
Tamura Ryo - - 2013
We have reported good control of atypical genital bleeding when using a cyclic administration of dienogest (repeated 4-week cycles, each consisting of the administration of 2 mg/day of dienogest for 3 weeks, followed by 1 week of drug withdrawal) in patients with endometriosis. Herein, we report the effectiveness of the ...
Han Yi - - 2013
To evaluate the incidence and characteristics of uterine bleeding during postoperative gonadotropin-releasing hormone agonist (GnRHa) treatment combined with the lowest effective dose of estrogen-progestogen add-back therapy in Chinese women of reproductive age with endometriosis. Seventy Chinese women aged 18 to 50 years with stage III or IV endometriosis and treated ...
Marsch S - - 2013
After years of advocating ABC (Airway-Breathing-Circulation), current guidelines of cardiopulmonary resuscitation (CPR) recommend CAB (Circulation-Airway-Breathing). This trial compared ABC with CAB as initial approach to CPR from the arrival of rescuers until the completion of the first resuscitation cycle. 108 teams, consisting of two physicians each, were randomized to receive ...
Hooper Nic - - 2013
In the thought suppression literature the completion of one suppression and one expression phase is called an indulgence cycle. The current study aimed to determine the effects on thought frequency of entering multiple indulgence cycles. Participants were assigned to one of two groups. The repeated suppression group was required to ...
Tsang Bonnie B Department of Surgery, Faculty of Medicine and Dentistry, University of Alberta, 2D WMC, 8440-112 Street NW, Edmonton, AB T6G 2B7, Canada. - - 2013
Advanced Trauma Life Support (ATLS) protocols provide a common approach for trauma resuscitations. This was a quality review assessing compliance with ATLS protocols at a Level I trauma center; specifically whether the presence or absence of a trauma team leader (TTL) influenced adherence. This retrospective study was conducted on adult ...
Woolley S D SD Department of General Surgery, Plymouth, PL6 - - 2013
Pre-operative assessment (POA) is now commonplace and follows established protocols. This audit compares the cost-effectiveness of surgeon-directed (SD) POA compared to the standard practice of protocol-driven (PD) POA. One hundred and fifty-six NHS patients who were referred to a single surgeon during 2009 were allocated to one of three groups. ...
Eftekhar Maryam M Department of Obstetrics and Gynecology, Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, - - 2013
This study compares the microdose flare-up protocol to the ultrashort gonadotropinreleasing hormone (GnRH) agonist flare combined with the fixed multidose GnRH antagonist protocol in poor responders undergoing ovarian stimulation. In this randomized clinical trial, 120 women who were candidates for assisted reproductive techniques (ART) and had histories of one or ...
Rubio Carmen - - 2012
OBJECTIVE: To evaluate the usefulness of preimplantation genetic screening (PGS) using fluorescence in situ hybridization (FISH) for two different indications: repetitive implantation failure (RIF) and advanced maternal age (AMA). DESIGN: Two prospective, randomized controlled trials with patients allocated in two arms: blastocyst transfer on day 5 (group A) or PGS ...
Kasivisvanathan R - - 2012
An epidural catheter breaking in a patient rarely occurs nowadays, with data suggesting an incidence of 1 in 60 000. This low incidence reflects advances in catheter construction and use of more robust synthetic polyamides such as nylon.
Joshi Santosh - - 2012
This study illustrates the status of thelotremoid Graphidaceae in South Korea. The taxonomy and systematics of thelotremoid lichens in the country have recently advanced greatly. Following the earlier known taxa from the group, four new records of the genus Thelotrema are reported and described briefly. An artificial key for all ...
Lombardi G - - 2012
Objective:To evaluate the clinical and urodynamic impact of intravesical electrostimulation (IVES) on incomplete spinal cord injury (SCI) patients suffering from chronic neurogenic non-obstructive urinary retention (N-NOR).Methods:One-hundred and two patients underwent at least 28 consecutive daily IVES sessions because objective evidence of detrusor acontractility instead of hypocontractility was detected. Diary entries ...
Lesimple Thierry - - 2012
Background Several cancer therapies can prolong cardiac repolarization. This study assessed the potential of eribulin to affect cardiac repolarization in patients with advanced solid tumors. Methods In this Phase I, open-label, single-arm study, patients received eribulin mesylate (1.4 mg/m(2); Days 1 and 8 of a 21-day cycle). The primary objective was ...
Junsheng Li - - 2013
To evaluate the impact of testicular sperm aspiration on the clinical outcomes of IVF patients with temporary ejaculation failure (TEF) on the day of oocyte retrieval. A case-control study. University-affiliated IVF center. One hundred eight infertile couples encountering TEF on the day of oocyte retrieval. Testicular sperm aspiration and intracytoplasmic ...
Abdel Mohsen Iman - - 2012
Background: To compare the IVF outcomes of letrozole/antagonist and microdose GnRH agonist flare up protocols in poor ovarian responders undergoing intracytoplasmic sperm injection. Materials and methods: A randomized controlled trial was performed in patients with one or more previous failed IVF cycles in which four or less oocytes were retrieved ...
Valldeoriola Francesc F Neurology Services, Movement Disorders Unit, Hospital Clinic i Provincial, Barcelona, - - 2013
To perform a comparative long-term analysis of the associated healthcare costs for the therapeutic options in advanced Parkinson's Disease (PD): deep brain stimulation (DBS), continuous duodenal levodopa-carbidopa infusion (CDLCI), and continuous subcutaneous apomorphine infusion (CSAI). Resource use associated with the pre-treatment period, procedure, and follow-up was assessed for the three ...
Jiménez-Candil Javier - - 2012
BACKGROUND: Antitachycardia pacing (ATP) fails to terminate 5-25 % of ventricular tachycardias (VT) occurring in ICD patients. We speculated that small fluctuations in VT cycle length (CL) may be related to the efficacy of the subsequent ATP. OBJECTIVE: To determine the relationship between the R-R variations of the last 12 ...
Oh Doo H - - 2012
PURPOSE:: To assess the long-term efficacy, refractive changes, and final visual acuity results from emmetropic presbyopic corrections when using aspheric ablation with the central-saving technique (CST) through the modulation of early wound healing. METHODS:: This study was a prospective comparative study. Twenty-four eyes of 12 patients with emmetropia underwent aspheric ...
Mont Michael A - - 2012
Because total knee arthroplasty is one of the most common orthopaedic procedures, it is important that the medical community continually strive for cost reductions. This prospective controlled trial aimed to determine if cost decreases could be achieved in non-navigated and navigated procedures by replacing traditional saws, cutting blocks, and trials ...
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