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Results 251 - 300 of 4684
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Mundis Gregory - - 2012
: This study analyzes the prevalence and risk factors for the development of PJK following lumbar PSO. The hypothesis was that PJK would develop early in the postoperative period at high rates in this population undergoing dramatic sagittal plane realignment, and that risk factors based on baseline and follow-up radiographs ...
Patil Arun-Angelo - - 2012
: The conventional procedure of hippocampectomy can impair memory. Furthermore, the hippocampus is the main source of stem cells. On the other hand, multiple hippocampal transection (MHT) can disrupt seizure circuits without loss of function or stem cells. In this presentation therefore, the authors will present long term outcomes in ...
Gourdine-Shaw Monique C - - 2012
Certain complex foot deformities can be corrected surgically with a U-osteotomy. This osteotomy is indicated for patients with a uniform deformity of the entire foot relative to the tibia, preexisting stiffness and/or fusion of the subtalar joint, and a pain-free ankle joint. The goal is to create a plantigrade foot ...
Choy-Shan Alana - - 2012
The purpose of this study was to assess the impact of rosiglitazone on survival in patients with diabetes mellitus (DM) and coronary artery disease (CAD). We carried out a drug-exposure analysis in 801 patients with DM and CAD in a cardiac catheterization laboratory registry (490 patients treated with a percutaneous ...
Chalouhi Nohra - - 2012
OBJECTIVE: Aneurysmal subarachnoid hemorrhage (SAH) is relatively uncommon in young adults. There is a paucity of data pertaining to the management of aneurysmal SAH in young patients, especially with endovascular therapy. METHODS: We reviewed all SAH patients under the age of 35 years treated at Jefferson Hospital for Neuroscience, Philadelphia, ...
Choi Wilson W - - 2012
A sutureless ward reduction (SWR) protocol was implemented in the neonatal intensive care unit of a tertiary level hospital in 1999. Although the short-term outcomes associated with SWR have been documented, the long-term outcomes are unknown. Retrospective data were collected from the medical records of all neonates with gastroschisis from ...
Charalambous Charalambos P - - 2012
Early posttraumatic elbow contractures may be treated with a combination of manipulation with the patient under anesthesia followed by bracing.Extrinsic contractures of the elbow may be treated with open or arthroscopic release, whereas intrinsic and combined contractures may require tissue release as well as partial or total arthroplasty.
Maeng Michael - - 2012
This study sought to examine the 3-year clinical outcomes in patients treated with the Endeavor (Medtronic, Santa Rosa, California) zotarolimus-eluting stent (ZES) or the Cypher (Cordis, Johnson & Johnson, Warren, New Jersey) sirolimus-eluting stent (SES) in routine clinical practice. The long-term clinical outcome in patients treated with ZES in comparison ...
Fehlings Michael G - - 2012
: While cervical spondylotic myelopathy (CSM) is the most common cause of spinal cord impairment worldwide, little is known regarding international variations in clinical presentation, management and outcomes of this condition. To address this key issue, we undertook a prospective multicenter study of CSM patients undergoing surgical treatment. : 486 ...
Brady Boyce Brenda A - - 2012
Background Nurses noted that the rate of phlebitis was high when intravenous amiodarone was infused via a peripheral site. Hospital policy recommends a central vascular catheter, but this method is often not feasible because the drug is administered in emergent situations for short periods. Objective To determine the rate and ...
Pinto Nigel - - 2012
Background: This study was designed to identify factors associated with return to work and quality of life in patients undergoing primary coronary artery bypass at age <50 years. Methods: 172 patients <50-years old underwent primary coronary artery bypass between January 2000 and December 2006. Predictors of return to work were ...
Seet Raymond C S - - 2012
Background: Symptomatic intracranial hemorrhage (SICH) is a devastating complication of intravenous thrombolysis treatment that is associated with high mortality. Clinical trials, stroke registries and cohort studies employ different case definitions to identify stroke patients with SICH following intravenous thrombolysis. We systematically reviewed the reported rates of SICH following intravenous thrombolysis ...
Forbes Jonathan - - 2012
: Dorsal root entry-zone (DREZ) lesioning is an important tool in the neurosurgeon's armamentarium for treatment of medically-refractory chronic pain syndromes associated with deafferentation of neurons located in the superficial Rexed layers of the spinal cord. The objective of this study was to retrospectively review the past 15 years of ...
Dyer Kenneth C - - 2012
Long-term changes in the dentitions of orthodontic patients have been studied. However, most studies in the literature report findings after only a few years posttreatment. In this study, we examined records an average of 24 years after active treatment. The purpose was to answer 2 questions: (1) does irregularity increase ...
Nordström Dan - - 2012
OBJECTIVE: To study the efficacy of anakinra versus disease-modifying antirheumatic drugs (DMARD) in refractory adult-onset Still's disease (AOSD). METHODS: In a 24-week study, 22 patients with AOSD taking prednisolone ≥ 10 mg/day received anakinra (n = 12) or DMARD (n = 10). The primary endpoint was achievement of remission. RESULTS: ...
Miller Ronald D - - 2012
BACKGROUND: Blood hemoglobin (Hb) can be continuously monitored utilizing noninvasive spectrophotometric finger sensors (Masimo SpHb). SpHb is not a consistently accurate guide to transfusion decisions when compared with laboratory Co-Oximetry (tHb). We evaluated whether a finger digital nerve block (DNB) would increase perfusion and, thereby, improve the accuracy of SpHb. ...
Harwin Steven F - - 2012
Revision total hip arthroplasty (THA) is associated with greater blood loss than primary THA. Jehovah's Witnesses will not accept transfusions of blood or blood products and are thus at an increased risk for complications due to perioperative anemia. The purpose of this study was to report the clinical outcomes, radiographic ...
Yang Isaac - - 2012
: Vestibular schwannoma (VS) is a skull base tumor most commonly in the CP angle. Hearing loss commonly occurs in varying degrees as a result of VS and can have a significant and lasting impact on quality of life. In this study, we compare the long term clinical outcomes of ...
Torres Silvio - - 2012
Introduction. Magnesium sulfate is a calcium antagonist that inhibits bronchial smooth muscle contraction promoting bronchodilation. It is used for the management of acute severe asthma in children; however most of the studies have been performed in adults. Objective. To evaluate the effectiveness of intravenous magnesium sulfate for the treatment of ...
Kim Tae Young - - 2012
Background: The efficacy and proper doses of steroid pulse therapy in patients with immunoglobulin A nephropathy (IgAN) have not been established. We therefore investigated the effects of methylprednisolone (MP) pulse therapy in patients with histologically active IgAN and established renal impairment at the time of treatment. Methods: We assessed 22 ...
Zhang Fan - - 2012
To assess the clinical and urodynamic results of sigmoidocolocystoplasty in patients with neurogenic bladder dysfunction. We retrospectively reviewed 78 augmentation enterocystoplasty cases in our database from 2005 to 2011 to identify 47 patients who had undergone sigmoidocolocystoplasty alone or combined with ureter reimplantation. The indications for surgery and postoperative complications ...
Al Asmari Abdulrahman K - - 2012
To study the clinical aspects and frequency of scorpion stings in Riyadh region of Saudi Arabia. Clinical aspects and frequency of scorpion sting cases reporting to 2 referral hospitals in the Riyadh region of Saudi Arabia were analyzed during May 2006 to April 2008. Data on demographic status, date and ...
Hörburger David - - 2012
Studies showing the effectiveness of therapeutic hypothermia (32-34°C) in postcardiac arrest patients have been criticized because of patients with elevated body temperature (>37.5°C) in the noncooled control group. Thus, the effects of spontaneous normothermia (<37.5°C) compared with mild therapeutic hypothermia were studied. Retrospective chart review from 1991 to 2010. Witnessed ...
Azizi Fereidoun - - 2012
There is no general agreement as to which treatment is best for hyperthyroidism. The objective of this study is to investigate the effectiveness of continuous methimazole (MMI) treatment and to compare the results of neuropsychological testing in patients receiving long-term continuous MMI to those on replacement thyroxine following radioiodine-induced (RAI) ...
Feldman Steven R - - 2012
Acne profoundly affects patients' lives, but the effect of treatment is not fully characterized. The purpose of this study was to explore patients' experiences and viewpoints regarding treatment for mild to moderate acne vulgaris. This was an open-label, single-center study of 30 patients with mild to moderate acne vulgaris, treated ...
Plotkin Scott R - - 2012
Early studies suggest that bevacizumab treatment can result in tumor shrinkage and hearing improvement for some patients with neurofibromatosis type 2 (NF2). The aim of this study was to report extended follow-up in a larger cohort of similarly treated patients. Retrospective study. Tertiary referral center Thirty-one consecutive NF2 patients who ...
Chastek Benjamin - - 2012
Treatment patterns, including persistence, gaps in therapy, switching, and discontinuation, were examined in patients with psoriatic arthritis (PsA) who received the tumor necrosis factor (TNF)-blockers etanercept or adalimumab. This retrospective study utilized administrative claims data from a United States commercial health plan. Adults (age 18-64 years) with PsA who started ...
Tonelli Francesco - - 2012
Various blockers of tumor necrosis factor-α are available for treatment of Crohn's disease. Randomized controlled trials have demonstrated the effects of systemic therapy with adalimumab, a fully humanized monoclonal antibody against tumor necrosis factor-α. The aim of this study was to investigate the effectiveness and safety of local injection of ...
Golfam M - - 2012
The objective of the present study was to evaluate the incidence, time of onset, and extent of hemoglobin, testosterone, and erythropoietin changes in patients with localized prostate cancer receiving either radiation alone or radiation combined with total androgen blockade (tab). The study enrolled 35 patients (median age: 69 years) with ...
Kim Tae-Hun - - 2012
Prolonged usage of extracorporeal membrane oxygenation (ECMO) may induce multi-organ failure. This study is aimed to evaluate prognostic factors in the patients with ECMO. Also, the prognosis of ECMO with Kidney Injury Network Scoring system is studied. From May 2005 to July 2011, 172 cases of ECMO were performed. The ...
Pandya Amit G - - 2012
To determine the efficacy and safety of deferasirox (an oral iron-chelating agent approved to reduce iron stores in patients with chronic iron overload due to blood transfusions) in a pilot trial for the treatment of patients with porphyria cutanea tarda (PCT), the most common of the porphyrias and often difficult ...
Pérez-Legaz Juan - - 2012
Application of nitroglycerin (glyceryl trinitrate) ointment with perianal administration is a widely used treatment for chronic anal fissure. However, headache occurs after application in 20% to 70% patients and leads to withdrawal in 10% of patients. The aim of the study was to investigate whether endoanal application of the ointment ...
Cornely Oliver A - - 2012
Recurrence of Clostridium difficile infection (CDI) occurs in approximately 25% of successfully treated patients. Two phase 3 randomized, double-blind trials were conducted at 154 sites in the United States, Canada, and Europe to compare fidaxomicin vs vancomycin in treating CDI. Patients with CDI received fidaxomicin 200 mg twice daily or ...
Louie Thomas J - - 2012
The microflora-sparing properties of fidaxomicin were examined during the conduct of a randomized clinical trial comparing vancomycin 125 mg 4 times per day versus fidaxomicin 200 mg twice per day for 10 days as treatment of Clostridium difficile infection (CDI). Fecal samples were obtained from 89 patients (45 received fidaxomicin, ...
Boonen Bert - - 2012
Patient-specific templating total knee arthroplasty (TKA) is a new method for alignment of a total knee arthroplasty that uses disposable guides. We present the results of the first 40 consecutive patients who were operated on using this technique. In this case-control study, we compared blood loss, operation time, and alignment ...
Holman Katherine M - - 2012
Serologic tests for syphilis results at the time of diagnosis are the basis for evaluating response to syphilis therapy. After treatment, however, serologic tests for syphilis titers may continue to increase for several weeks. We evaluated rapid plasma reagin (RPR) titer variation during the 14 days after therapy using data ...
Halpin Chris - - 2012
To report the pretreatment and posttreatment population characteristics and the overall stability of the audiologic outcomes found during the Sudden Hearing Loss Clinical Trial (ClinicalTrials.gov: Identifier NCT00097448). Multicenter, prospective randomized noninferiority trial of oral versus intratympanic (IT) steroid treatment of sudden sensorineural hearing loss (SSNHL). Fifteen academically based otology practices. ...
Wagemakers Harry P A - - 2012
Prognosis of persistent complaints after knee injury is based on secondary care populations. In a primary care setting, however, no studies have addressed this issue. To identify possible predictors of persistent complaints 1 year after a knee injury. These predictors are important for guiding the GP's therapeutic management, and giving ...
Brown Joshua B - - 2012
Helicopter transport (HT) is an important component of American trauma care, but prospectively identifying patients that would benefit from this resource remains difficult. The objective of this study was to assess the role of the National Trauma Triage Protocol (NTTP) in selecting patients that would benefit from HT. Subjects transported ...
Roldán V V Hematology and Medical Oncology Unit, Hospital Universitario Morales Meseguer, University of Murcia, Murcia, - - 2012
There are limited data on the prognostic role of biomarkers in anticoagulated patients with atrial fibrillation (AF). We evaluated the prognostic value of high sensitivity TnT (hsTnT) and high-sensitivity interleukin-6 (hsIL6) in a large cohort of AF patients taking oral anticoagulant therapy (OAC) as both biomarkers have been associated with ...
Fox Matthew P MP Center for Global Health and Development, Boston University, 801 Massachusetts Ave., Boston, MA 02118, USA. - - 2012
To measure rates and predictors of virologic failure and switch to second-line antiretroviral therapy (ART) in South Africa. : Observational cohort study. We included ART-naive adult patients initiated on public sector ART (January 2000 to July 2008) at 5 sites in South Africa who completed ≥6 months of follow-up. We ...
Yi Rang - - 2012
BackgroundUnilateral biliary metallic stent placement in the lobe with patent portal vein seemed to be a safe and effective palliative treatment of patients with contralateral portal vein occlusion caused by advanced hilar malignancy, obviating bilateral stent placement in these patients, because the hepatic lobe with portal vein occlusion ceases to ...
García-Ramos S E - - 2012
OBJECTIVE: To analyse whether the change of antiretroviral therapy to efavirenz/emtricitabine/tenofovir in a single daily dose (EETu) increases adherence and maintains effectiveness, and establish the cost increase caused by the change. METHODS: An observational, retrospective, and intra-subject study, performed in the outpatient dispensing unit. The study period was 1 year ...
Wong George Kwok Chu - - 2012
ObjectiveIdentification of patients with aneurysmal subarachnoid haemorrhage (aSAH) with cognitive impairment is important for patient management (medical treatment, cognitive rehabilitation and social arrangements). The Montreal Cognitive Assessment (MoCA) is currently recommended over the Mini-Mental State Examination (MMSE) by the US National Institute of Neurological Disorder, in the chronic post-stroke setting. ...
Caudle Abigail S - - 2012
INTRODUCTION: The ACOSOG Z0011 trial has been described as practice-changing. The goal of this study was to determine the impact of the trial on surgeon practice patterns at our institution. METHODS: This is a review of practice patterns comparing the year before release of Z0011 to the year after an ...
Schuette Albert J - - 2012
BACKGROUND: Epsilon aminocaproic acid (EACA) has been used in the past to prevent cerebral aneurysm rerupture. Recent studies have indicated that short-term treatment with EACA can lower rebleeding rates without significantly increasing ischemic or thrombotic complications or permanent shunt rates. The goal of this study is to determine the efficacy ...
Dávalos Antoni - - 2012
BACKGROUND AND PURPOSE: The purpose of this study was to evaluate safety and efficacy of the Solitaire FR device in the treatment of patients with acute ischemic stroke secondary to large artery occlusion. METHODS: We conducted a retrospective study of consecutive patients presenting with acute ischemic stroke treated with Solitaire ...
Khokhar Arif - - 2012
INTRODUCTION: Patients undergoing knee arthroplasty are at high risk of developing post-operative deep vein thrombosis (DVT) or a pulmonary embolus (PE). Despite best efforts, the best prophylaxis for thromboembolic disease remains controversial. This article aims to update the reader on the newest guidelines concerning venous thromboembolism (VTE) prophylaxis for elective ...
Cho Sung Do - - 2012
PURPOSE: Unsteady ambulation shortly after total knee arthroplasty (TKA) may cause falling. Postural sway may predict the risk of falling. This prospective single-blinded observational study therefore evaluated the effects of TKA on single-limb standing balance (SLSB) and factors related to change in SLSB. METHODS: Patients with varus deformity and medial ...
Gao Jun - - 2012
OBJECTIVE: We aimed to assess the feasibility, safety, and efficacy of radiofrequency (RF) ablation for the treatment of large (≥5 cm in greatest diameter) hepatic hemangiomas. METHODS: Thirty-six patients (15 male, 21 female; mean age 50 years) with 41 hepatic hemangiomas ≥5 cm in diameter were enrolled and treated with ...
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