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Results 251 - 300 of 4743
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Chen Shao-Quan - - 2012
BACKGROUND: Traction method is important to stapled haemorrhoidopexy (SH) for its impact on haemorrhoidal prolapse reduction. Single purse string with one-point traction is most commonly used in SH. This traction method often results in an irregular mucosal doughnut with inadequate height, which leads to insignificant and uneven haemorrhoidal prolapse reduction. ...
Chládek J - - 2012
Background  Low-dose oral methotrexate (MTX) is an effective immunosuppressive therapy for chronic plaque psoriasis. However, its use is hampered by the risk of liver fibrosis. Aim  To compare the results of serial measurements of serum fibrosis markers during the remission-induction phase of treatment with MTX to those of patients on ...
Chen Ping-Hsien - - 2012
BACKGROUND & AIMS: Active bleeding is a poor prognostic indicator in patients with acute esophageal variceal bleeding. This study aimed to determine indicators of 6-week re-bleeding and mortality in patients with "active" esophageal variceal bleeding, particularly emphasis on the presenting symptoms and timing of endoscopy to define the treatment strategy. ...
Daïen Claire Immediato - - 2012
BACKGROUND: Cardiovascular mortality is increased in patients with rheumatoid arthritis (RA). RA is associated with an increased left ventricular mass index (LVMI), a strong marker of cardiovascular mortality, and vessel abnormalities. Experimental studies have suggested that tumour necrosis factor α (TNFα) may induce LV hypertrophy. OBJECTIVE: To study the effect ...
Wang Jiawan - - 2012
Post-operative cognitive dysfunction (POCD), especially in elderly patients, has been reported in many studies. Although increasing age, duration of anesthesia, postoperative infections, and respiratory complications were regarded as the risk factors for POCD, no extracerebral diagnostic biomarkers have been identified as indicators of POCD. Ninety-five patients, ages 65-80 years, scheduled for ...
Snipelisky David - - 2012
INTRODUCTION: Although warfarin has traditionally been used for reducing risk of stroke in patients with atrial fibrillation, over the past year, the direct thrombin inhibitor dabigatran has become an accepted alternative. No study has conclusively investigated bleeding risks of patients treated with dabigatran immediately following radiofrequency catheter ablation (RFCA) procedures. ...
Garcia-Lopes Miriam G - - 2012
Background/Aims: Hypovitaminosis D is highly prevalent among patients with chronic kidney disease (CKD) and has been associated with poor outcome. We aimed to test the effect of a protocol of cholecalciferol supplementation on the restoration of vitamin D status and on parathyroid hormone (PTH) levels in patients with CKD. Methods: ...
Pacini Davide - - 2012
BACKGROUND: Little epidemiological information on acute aortic dissection (AAD) is available in the literature. The objective of the present study was to determine the incidence and mortality rates of AAD in the general population and to analyze its clinical features. METHODS: Data from the Emilia-Romagna regional database of hospital admissions ...
- - 2012
BACKGROUND: Dual antiplatelet therapy with clopidogrel and aspirin reduces the presence and number of microembolic signals in patients with large artery disease. However, whether it is effective in patients with intracranial disease alone remains uncertain. We performed a subgroup analysis of the The CLopidogrel plus Aspirin for Infarction Reduction (CLAIR ...
de Buck van Overstraeten Anthony A Department of Abdominal Surgery, University Hospital Gasthuisberg Leuven, Leuven, - - 2012
Crohn's disease (CD) is a chronic inflammatory bowel disease that can affect the entire gastrointestinal tract. Ultimately, up to 70% of all patients will need surgery, despite optimized medical therapy. Moreover, about half of the patients will need redo-surgery because of disease recurrence. The introduction of anti-tumor necrosis factor (TNF) ...
Sardi Gabriel L - - 2012
OBJECTIVES: This study aimed to compare percutaneous coronary intervention (PCI) with direct stenting (DS) to balloon pre-dilatation (PD) for patients undergoing elective PCI to determine whether there is an independent value for DS with regard to clinical outcomes. BACKGROUND: The safety of PCI with DS has been established, but the ...
Claessen Bimmer E - - 2012
BACKGROUND: This study sought to investigate whether there is a differential prognostic effect of successful percutaneous coronary intervention (PCI) of chronic total occlusions (CTO) according to the target vessel the CTO is located in. METHODS: Between 1998 and 2007, a total of 1,791 patients underwent PCI of a CTO at ...
Cam Akin - - 2012
OBJECTIVES: Our aim was to report outcomes of percutaneous stenting of carotid stenosis in patients with previous neck radiation. BACKGROUND: Post-irradiation carotid disease is often extensive and involves atypical areas. Data regarding outcomes of stenting of these lesions are scarce. METHODS: We retrospectively reviewed medical records at our institution from ...
Tobbia Patrick - - 2012
OBJECTIVE: To compare outcomes between US and non-US (OUS) sites in patients with non ST-elevation acute coronary syndromes (NSTEACS) and to evaluate potential reasons for differences in outcomes. BACKGROUND: There are little data comparing outcomes at US versus OUS sites in patients with NSTEACS managed with an invasive strategy. METHODS: ...
Van Mieghem Nicolas M - - 2012
OBJECTIVES: To evaluate survival and cause of death in a consecutive patient cohort undergoing Transcatheter Aortic Valve implantation (TAVI). BACKGROUND: TAVI is a valid treatment option in patients with severe Aortic Stenosis (AS) who are deemed at (very) high operative risk. Because of (non-)cardiac co-morbidities life expectancy in this patient ...
Thomson W L - - 2012
Warfarin is increasingly prescribed in the elderly population for a number of medical conditions. Pre-tibial haematomas are a common cause of morbidity in this group. The aim of the study was to identify the proficiency of INR monitoring at a primary care level in correlation with their recommended INR range ...
Walsh Mark - - 2012
Pallid breath-holding (PBH) is a childhood condition that presents with recurrent syncope. Although typically benign, severe cases can lead to asystole and anoxic seizures. Previous studies have advocated pacemaker placement to abbreviate symptoms. This was a retrospective study of patients treated with fluoxetine for PBH spells. Clinical response, side effects ...
Stryjewski Martin E - - 2012
TD-1792 is a first-in-class glycopeptide-cephalosporin heterodimer that exhibits bactericidal activity against Gram-positive pathogens. We conducted a randomized, double-blind, active-control, phase II trial in patients with complicated skin and skin structure infections caused by suspected or confirmed Gram-positive organisms. Patients 18 to 65 years old were randomized to receive 7 to ...
Scrivo Rossana - - 2012
Screening for latent tuberculosis infection (LTBI) prior to the prescribing of anti-TNF agents and monitoring for infection during treatment are recommended. The feasibility of novel screening tools, including QuantiFERON-TB Gold In-Tube (QFT-GIT), remains unclear in the setting of immunosuppression. The aim of this study was to evaluate the usefulness of ...
Callejas M A - - 2012
BACKGROUND: Involuntary craniofacial erythema, or blushing, due to autonomic dysfunction can be a cause of psychological distress. Although anecdotal reports have suggested that pharmacologic treatments or cognitive behavioral therapy can be used to treat the condition, no rigorous analyses of their efficacy have been reported. OBJECTIVES: To assess the efficacy ...
Himpens Jacques - - 2012
This retrospective study aimed to evaluate the long-term results of the laparoscopic Roux-en-Y gastric bypass (LRYGB) procedure performed at our department of bariatric surgery. The 126 consecutive patients treated by LRYGB between January 1, 2001 and December 31, 2002 were analyzed in August 2011. Seventy-seven patients (61.1 %), including 18 ...
Issa Nidal - - 2012
BACKGROUND: Diverticulosis of the right colon occurs in a small percentage of patients in Western countries. Clinical presentation of right-sided colon diverticulitis is indistinguishable from that of acute appendicitis, and the majority of patients undergo surgical intervention for presumed appendicitis. The liberal use of diagnostic radiological modalities whenever appendicitis was ...
Ong Marcus Eng Hock - - 2012
ABSTRACT: INTRODUCTION: It has been unclear if mechanical cardiopulmonary resuscitation (CPR) is a viable alternative to manual CPR. We aimed to compare resuscitation outcomes before and after switching from manual CPR to load-distributing band (LDB) CPR in a multi-center emergency department (ED) trial. METHODS: We conducted a phased, prospective cohort ...
López-García José S - - 2012
OBJECTIVE: To assess the effect of the use of containers with an adapted sterilizing filter on the contamination of autologous serum eyedrops. DESIGN: Prospective, consecutive, comparative, and randomized study. PARTICIPANTS: Thirty patients with Sjögren syndrome. METHODS: One hundred seventy-six autologous serum containers used in home therapy were studied; 48 of ...
Kumagai Hiroo - - 2012
Background: Our previous placebo-controlled, prospective, double-blind study demonstrated that a new opioid ĸ-receptor agonist, nalfurafine hydrochloride, effectively reduced treatment-resistant pruritus in 337 hemodialysis patients. Thus, we designed this study to evaluate prospectively the efficacy, safety, addiction liability, and pharmacokinetics of nalfurafine given orally for 1 year. Methods: This open-label study ...
Barreras Ferran - - 2012
Purpose: Catheter obstruction or patency inhibition of the venous access cannula is a frequently experienced problem in patients to whom intravenous (IV) solutions are administered. In this study we assessed the efficacy and safety of Securflux® a disposable device with a back-check valve to prevent reflux in IV infusion sets. ...
Oteo-Álvaro Angel - - 2012
Background and Objective: Hip and knee osteoarthritis is highly prevalent in the elderly, and the incidence is estimated to increase in the coming decades. Prior to surgery, symptomatic treatment, starting with non-pharmacological therapies, should be prescribed. Paracetamol (acetaminophen) is the recommended first pharmacological treatment for osteoarthritis. If paracetamol is ineffective, ...
Tamasauskas Arimantas - - 2012
BACKGROUND: Long-term dopamine agonist (DA) therapy is recommended as a first-line approach for the management of microprolactinomas. However, DA therapy may be poorly tolerated by some patients, and therefore some patients continue to prefer surgery over DA therapy. AIM: The aim of our study was to evaluate factors associated with ...
Hunter Christopher L - - 2012
OBJECTIVE: Exhaled end-tidal carbon dioxide (Etco(2)) concentration is associated with lactate levels in febrile patients. We assessed the association of Etco(2) with mortality and lactate levels in patients with suspected sepsis. METHODS: This was a prospective observational study. We enrolled 201 adult patients presenting with suspected infection and 2 or ...
Tam Dong T H DT University of Medicine and Pharmacy of Ho Chi Minh City, Viet - - 2012
Patients with dengue can experience a variety of serious complications including hypovolemic shock, thrombocytopenia, and bleeding. These problems occur as plasma viremia is resolving and are thought to be immunologically mediated. Early corticosteroid therapy may prevent the development of such complications but could also prolong viral clearance. We performed a ...
Sirak John H - - 2012
In accordance with the Cox-Maze paradigm, successful treatment of atrial fibrillation (AF) requires (1) complete posterior left atrial isolation, (2) elimination of corridors for perimitral reentry, (3) elimination of cardiac venous (superior vena cava and coronary sinus) arrhythmogenic foci, (4) complete autonomic denervation, and (5) occlusion or removal of the ...
Organ Michael - - 2012
BACKGROUND:: Patients who develop castration-resistant prostate cancer (CRPCa) typically continue on androgen deprivation therapy (ADT). Whether these patients need to remain on ADT has not been well studied. We conducted a multicenter randomized trial to compare an intermittent versus continuous approach to ADT in CRPCa patients. Overall survival, health-related quality ...
Ciccone Marco Matteo - - 2012
INTRODUCTION: Previous studies support the fact that extracorporeal shockwave (SW) induces angiogenesis and improves symptoms in patients affected by limb ischemia. The aim of this study was to evaluate the effects of SW therapy in patients with peripheral artery disease (PAD). METHODS: Twenty-two patients were enrolled in this study and ...
Jervis-Bardy Joshua - - 2012
OBJECTIVES/HYPOTHESIS: Chronic rhinosinusitis (CRS) recalcitrant to surgery is a frustrating clinical entity. Recently, mupirocin sinonasal rinses have been suggested as an efficacious treatment alternative in these patients where Staphylococuccus aureus infection is demonstrated. To our knowledge, how best to treat this S aureus reservoir has not been previously evaluated in ...
Sasajima Y - - 2012
OBJECTIVES: To preoperatively determine candidates at definitive risk of postoperative delirium (POD), we identified relevant factors in patients with arteriosclerosis obliterans who underwent bypass surgery. DESIGN: A prospective cohort study. PATIENTS AND METHODS: 299 patients (age ≥60 years) who underwent bypasses in 1995-2006 were enrolled. Cognitive impairment was assessed by ...
Gu Qiang - - 2012
Aim  To investigate the maternal homocysteine (Hcy), folate, vitamin B(12) and B(6) , and their relations to neural tube defects (NTDs). Methods 30 mothers of NTDs offspring and another 60 mothers of normal children were enrolled as the patient and control groups from Xinjiang, China from Jan 2008 to May ...
Kozma Chris M - - 2012
To examine opioid prescription claims before and after initiation of pregabalin in patients with a diagnosis of diabetic peripheral neuropathy (DPN). This retrospective analysis used a national commercial database of integrated inpatient, outpatient, and prescription claims to identify adults with a DPN diagnosis code within 360 days prior to the ...
Sanelli P C PC Departments of Radiology, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, New York 10065, USA. - - 2013
DCI is a serious complication following aneurysmal SAH and remains a leading cause of morbidity and mortality. Our aim was to evaluate CTP in aneurysmal SAH by using outcome measures of DCI. This was a retrospective study of consecutive patients with SAH enrolled in a prospective institutional review board-approved clinical ...
Kennedy Fiona - - 2012
To present the results of the nonrandomized arm of the Cervical Artery Dissection in Stroke Study (CADISS-NR) trial, comparing anticoagulation and antiplatelets for prevention of recurrent stroke after carotid and vertebral dissection, and perform a meta-analysis of these results with previously published studies comparing the 2 therapeutic strategies. A total ...
Abuchar Adriana - - 2012
Background: Etanercept has been used to treat chronic plaque psoriasis. Previously reported data demonstrated that some patients experienced secondary failure and frequently rotational-switch therapy is used. The re-treatment with etanercept as part of the rotational therapy could be considered as another safe and efficient therapeutic approach. Objective: To evaluate the ...
Baumann F - - 2012
The aim of this paper was to evaluate the efficacy of a novel 4-F compatible self-expanding Nitinol stent for the treatment of long femoro-popliteal obstructions. This retrospective analysis includes patients with femoro-popliteal obstructions ≥120 mm in length, treated with a novel Nitinol stent (Pulsar-18) between February 2010 and December 2011. ...
Elalfy Mohsen S - - 2012
Background: Surgery and intensive factor VIII (FVIII) replacement may be risk factors for development of inhibitors. Objective: To evaluate time and rate of inhibitor development postcircumcision over 12-month period, and to assess bleeding of children with severe hemophilia A after low-dose FVIII replacement and local hemostasis. Patients and Methods: Sixty-one ...
Nomura Osamu - - 2012
OBJECTIVES: Little is known about the relationship between prior treatment with antibiotics and delay of diagnosis and treatment in pediatric acute appendicitis (AA). We have defined a situation requiring more than 48 hours from the onset of symptoms to surgery in pediatric AA as "therapeutic delay." The aim of this ...
Davies Andrew R - - 2012
OBJECTIVE:: Current guidelines recommend enteral nutrition in critically ill adults; however, poor gastric motility often prevents nutritional targets being met. We hypothesized that early nasojejunal nutrition would improve the delivery of enteral nutrition. DESIGN:: Prospective, randomized, controlled trial. SETTING:: Seventeen multidisciplinary, closed, medical/surgical, intensive care units in Australia. PATIENTS:: One ...
Morton Ryan - - 2012
: A paucity of patients with ruptured basilar apex aneurysms have been analyzed with long-term clinical results. : Sixty-one consecutive ruptured basilar apex aneurysms from 2005 to 2011 were retrospectively reviewed. A team-oriented approach was used to decide treatment. Clipping was typically used in younger patients, those with a complex ...
Mohammadi Alireza Mohammad - - 2012
: Trigeminal neuralgia (TN) is relatively frequent in Multiple Sclerosis (MS) patients and procedural treatments are less effective than when used for classical TN. Outcomes from direct comparisons between different procedures for MS-related TN is lacking. In this study, initial pain-free rates (IPFR), duration of pain-free intervals (PFI) and associated ...
Stefanovic Vedran - - 2012
Objective. To analyse the effectiveness of intravenous sulprostone infusion for the treatment of retained placenta without massive primary hemorrhage among patients at a university hospital over a three-year period. Design. Retrospective observational study. Setting. University teaching hospital. Population. 126 consecutive women with placental retention and intravenous sulprostone infusion as primary ...
Düzgün Irem - - 2012
This study aims to compare the efficacy of manual therapy in the frozen shoulder patients with or without diabetes mellitus. Between May 2006 and January 2008, 50 patients (10 males, 40 females; mean age 52±10 years; range 40 to 65 years) orthopedic surgeons referred to the Sports Physiotherapy Unit were ...
Thaci Bart - - 2012
: Patient-filled questionnaires, such as Oswestry Disability Index (ODI) or Neck Disability Index (NDI) have become the mainstay in the evaluation of treatment outcomes in degenerative spine disease (DSD), replacing result-reporting by surgeons. In this study we set to compare patients' and surgeons' assessment of spine treatment outcome in a ...
Slottosch Ingo - - 2012
BACKGROUND: We assessed the short-term outcomes and predictors of 30-d mortality in patients requiring temporary, peripheral extracorporeal membrane oxygenation (ECMO) for postcardiotomy cardiac failure. METHODS: The data were retrospectively obtained using our institutional patient database. All patients who had received peripheral ECMO support after surgery for acquired heart disease from ...
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