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Results 251 - 300 of 4759
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Clark Whalen - - 2012
INTRODUCTION: There is increasing focus on disease-specific outcomes. This study was undertaken to analyze early mortality after pancreaticoduodenectomy as part of a strategy to improve long-term outcome. METHODS: One thousand thirty-one patients who underwent pancreaticoduodenectomy from 1992 to 2010 were studied. Median data are reported. RESULTS: Fifty-eight (5.6 %) patients died ...
Vender Ronald - - 2012
Background: Data investigating the effect of etanercept on work productivity and healthcare resource utilization in Canadian patients in a clinical setting is limited. Objective: The aim of the study was to describe work productivity and healthcare resource utilization in patients with psoriasis prescribed etanercept. Methods: A 12-month, phase IV, non-randomized, ...
Aydin Scott I - - 2012
BACKGROUND: The RIFLE criteria (risk, injury, failure, loss, and end-stage kidney disease) have been used to assess acute kidney injury (AKI) in various populations of critically ill children. There are limited reports of AKI using RIFLE criteria in large pediatric populations undergoing congenital heart disease surgery. METHODS: Records of patients ...
Poi Mun Jye - - 2012
BACKGROUND: Little is known about the role of percutaneous revascularization of the profunda femoral artery (PFA) in patients with amputation stump ischemia who are at risk of hip disarticulation. METHODS: We identified 4 patients who were treated for persistent amputation stump ischemia by PFA percutaneous revascularization over a 3-year period. ...
Lehmann Laura - - 2012
BACKGROUND: Hyper- and hyponatremia are frequently observed in patients after subarachnoidal hemorrhage, and are potentially related to worse outcome. We hypothesized that the fluid regimen in these patients is associated with distinct changes in serum electrolytes, acid-base disturbances, and fluid balance. METHODS: Thirty-six consecutive patients with SAH were randomized double-blinded ...
Sturiale Carmelo Lucio - - 2012
Hemorrhagic contusions (HC) represent a common consequence of traumatic brain injury (TBI) and usually evolve during the first 12 hours after trauma. The relationship between decompressive craniectomy (DC) and evolution of the post-traumatic HC is still unclear. The aim of the present study was to evaluate the impact of DC ...
Shiga Taro - - 2012
Background: Patients with biventricular assist device (BiVAD) placement have a poor prognosis, but preoperative risk factors for the necessity of BiVAD have not been fully elucidated. Methods and Results: Data from 79 patients who received left ventricular assist device (LVAD) between November 2002 and December 2011 were retrospectively reviewed. Overall, 9 patients ...
Isbister Geoffrey K - - 2012
BACKGROUND: Snakebites in snake handlers are an important clinical problem that may differ to bites in the general population. AIM: To investigate the epidemiology and clinical presentation of bites in snake handlers. DESIGN: Prospective observational study. METHODS: Bites in snake handlers recruited as part of the Australian Snakebite Project (ASP) ...
Peolsson Anneli - - 2012
ABSTRACT: Study Design. Prospective randomized study.Objective. To investigate differences in physical functional outcome in patients with radiculopathy due to cervical disc disease (CDD), after structured physiotherapy alone (consisting of neck-specific exercises with a cognitive behavioral approach) versus after anterior cervical decompression and fusion (ACDF) followed by the same structured physiotherapy ...
Ichiyanagi Osamu - - 2012
Abstract Objective. The aim of this study was to assess stone-free rates following extracorporeal shockwave lithotripsy (ESWL) of pure calcium oxalate (CaOx) stones in the proximal ureter. Material and methods. The investigators retrospectively examined 53 patients with 5-10 mm pure CaOx stones in the proximal ureter from the medical archives ...
Charitos Efstratios I - - 2012
OBJECTIVES: Reinterventions after the Ross procedure are a concern for patients and treating physicians. The scope of the present report was to provide an update on the reinterventions observed in the large patient population of the German-Dutch Ross Registry. PATIENTS AND METHODS: From 1988 to 2011, 2023 patients (age, 39.05 ...
Ong K L - - 2012
The costs for treating kypho- and vertebroplasty patients were evaluated at up to 2 years postsurgery. There were no significant differences in adjusted costs in the first 9 months postsurgery, but kyphoplasty patients were associated with significantly lower adjusted treatment costs by 6.8-7.9 % in the remaining periods through 2 years postsurgery. INTRODUCTION: Vertebral ...
Schou Morten M Department of Cardiology and Endocrinology, Frederiksberg University Hospital, DK-2000 Frderiksberg, Denmark. - - 2013
Outpatient follow-up in specialized heart failure clinics (HFCs) is recommended by current guidelines and implemented in most European countries, but the optimal duration of HFC programmes has not been established. Nor is it known whether all or only high-risk patients, e.g. identified by NT-proBNP, might benefit from an extended HFC ...
Power Sarah - - 2012
PURPOSE: Radiologically inserted gastrostomy (RIG) is an established way of maintaining enteral nutrition in patients who cannot maintain nutrition orally. The purpose of this study was to evaluate the safety and efficacy of primary placement of a wide bore button gastrostomy in a large, varied patient population through retrospective review. ...
Biedermann Luc - - 2012
BACKGROUND AND AIMS: A significant fraction of patients with ulcerative colitis (UC) is not sufficiently controlled with conventional therapy or suffers from therapy related side effects. Anthocyanins, highly abundant in bilberries (Vaccinium myrtillus), were shown to have antioxidative and anti-inflammatory effects. We aimed to explore the therapeutic potential of bilberries ...
Osawa Aiko - - 2012
This retrospective study examined the effectiveness of cilostazol in preventing aspiration pneumonia in patients with acute cerebral infarction. The 189 subjects ranged in age from 31 to 95 years and included 57 with small-artery occlusion, 107 with large-artery atherothrombosis, and 25 with other disorders. Patients with cardiogenic cerebral embolism or ...
Chen Shao-Quan - - 2012
BACKGROUND: Traction method is important to stapled haemorrhoidopexy (SH) for its impact on haemorrhoidal prolapse reduction. Single purse string with one-point traction is most commonly used in SH. This traction method often results in an irregular mucosal doughnut with inadequate height, which leads to insignificant and uneven haemorrhoidal prolapse reduction. ...
Chládek J - - 2012
Background  Low-dose oral methotrexate (MTX) is an effective immunosuppressive therapy for chronic plaque psoriasis. However, its use is hampered by the risk of liver fibrosis. Aim  To compare the results of serial measurements of serum fibrosis markers during the remission-induction phase of treatment with MTX to those of patients on ...
Chen Ping-Hsien - - 2012
BACKGROUND & AIMS: Active bleeding is a poor prognostic indicator in patients with acute esophageal variceal bleeding. This study aimed to determine indicators of 6-week re-bleeding and mortality in patients with "active" esophageal variceal bleeding, particularly emphasis on the presenting symptoms and timing of endoscopy to define the treatment strategy. ...
Daïen Claire Immediato - - 2012
BACKGROUND: Cardiovascular mortality is increased in patients with rheumatoid arthritis (RA). RA is associated with an increased left ventricular mass index (LVMI), a strong marker of cardiovascular mortality, and vessel abnormalities. Experimental studies have suggested that tumour necrosis factor α (TNFα) may induce LV hypertrophy. OBJECTIVE: To study the effect ...
Wang Jiawan - - 2012
Post-operative cognitive dysfunction (POCD), especially in elderly patients, has been reported in many studies. Although increasing age, duration of anesthesia, postoperative infections, and respiratory complications were regarded as the risk factors for POCD, no extracerebral diagnostic biomarkers have been identified as indicators of POCD. Ninety-five patients, ages 65-80 years, scheduled for ...
Snipelisky David - - 2012
INTRODUCTION: Although warfarin has traditionally been used for reducing risk of stroke in patients with atrial fibrillation, over the past year, the direct thrombin inhibitor dabigatran has become an accepted alternative. No study has conclusively investigated bleeding risks of patients treated with dabigatran immediately following radiofrequency catheter ablation (RFCA) procedures. ...
Garcia-Lopes Miriam G - - 2012
Background/Aims: Hypovitaminosis D is highly prevalent among patients with chronic kidney disease (CKD) and has been associated with poor outcome. We aimed to test the effect of a protocol of cholecalciferol supplementation on the restoration of vitamin D status and on parathyroid hormone (PTH) levels in patients with CKD. Methods: ...
Pacini Davide - - 2012
BACKGROUND: Little epidemiological information on acute aortic dissection (AAD) is available in the literature. The objective of the present study was to determine the incidence and mortality rates of AAD in the general population and to analyze its clinical features. METHODS: Data from the Emilia-Romagna regional database of hospital admissions ...
- - 2012
BACKGROUND: Dual antiplatelet therapy with clopidogrel and aspirin reduces the presence and number of microembolic signals in patients with large artery disease. However, whether it is effective in patients with intracranial disease alone remains uncertain. We performed a subgroup analysis of the The CLopidogrel plus Aspirin for Infarction Reduction (CLAIR ...
de Buck van Overstraeten Anthony A Department of Abdominal Surgery, University Hospital Gasthuisberg Leuven, Leuven, - - 2012
Crohn's disease (CD) is a chronic inflammatory bowel disease that can affect the entire gastrointestinal tract. Ultimately, up to 70% of all patients will need surgery, despite optimized medical therapy. Moreover, about half of the patients will need redo-surgery because of disease recurrence. The introduction of anti-tumor necrosis factor (TNF) ...
Sardi Gabriel L - - 2012
OBJECTIVES: This study aimed to compare percutaneous coronary intervention (PCI) with direct stenting (DS) to balloon pre-dilatation (PD) for patients undergoing elective PCI to determine whether there is an independent value for DS with regard to clinical outcomes. BACKGROUND: The safety of PCI with DS has been established, but the ...
Claessen Bimmer E - - 2012
BACKGROUND: This study sought to investigate whether there is a differential prognostic effect of successful percutaneous coronary intervention (PCI) of chronic total occlusions (CTO) according to the target vessel the CTO is located in. METHODS: Between 1998 and 2007, a total of 1,791 patients underwent PCI of a CTO at ...
Cam Akin - - 2012
OBJECTIVES: Our aim was to report outcomes of percutaneous stenting of carotid stenosis in patients with previous neck radiation. BACKGROUND: Post-irradiation carotid disease is often extensive and involves atypical areas. Data regarding outcomes of stenting of these lesions are scarce. METHODS: We retrospectively reviewed medical records at our institution from ...
Tobbia Patrick - - 2012
OBJECTIVE: To compare outcomes between US and non-US (OUS) sites in patients with non ST-elevation acute coronary syndromes (NSTEACS) and to evaluate potential reasons for differences in outcomes. BACKGROUND: There are little data comparing outcomes at US versus OUS sites in patients with NSTEACS managed with an invasive strategy. METHODS: ...
Van Mieghem Nicolas M - - 2012
OBJECTIVES: To evaluate survival and cause of death in a consecutive patient cohort undergoing Transcatheter Aortic Valve implantation (TAVI). BACKGROUND: TAVI is a valid treatment option in patients with severe Aortic Stenosis (AS) who are deemed at (very) high operative risk. Because of (non-)cardiac co-morbidities life expectancy in this patient ...
Thomson W L - - 2012
Warfarin is increasingly prescribed in the elderly population for a number of medical conditions. Pre-tibial haematomas are a common cause of morbidity in this group. The aim of the study was to identify the proficiency of INR monitoring at a primary care level in correlation with their recommended INR range ...
Walsh Mark - - 2012
Pallid breath-holding (PBH) is a childhood condition that presents with recurrent syncope. Although typically benign, severe cases can lead to asystole and anoxic seizures. Previous studies have advocated pacemaker placement to abbreviate symptoms. This was a retrospective study of patients treated with fluoxetine for PBH spells. Clinical response, side effects ...
Stryjewski Martin E - - 2012
TD-1792 is a first-in-class glycopeptide-cephalosporin heterodimer that exhibits bactericidal activity against Gram-positive pathogens. We conducted a randomized, double-blind, active-control, phase II trial in patients with complicated skin and skin structure infections caused by suspected or confirmed Gram-positive organisms. Patients 18 to 65 years old were randomized to receive 7 to ...
Scrivo Rossana - - 2012
Screening for latent tuberculosis infection (LTBI) prior to the prescribing of anti-TNF agents and monitoring for infection during treatment are recommended. The feasibility of novel screening tools, including QuantiFERON-TB Gold In-Tube (QFT-GIT), remains unclear in the setting of immunosuppression. The aim of this study was to evaluate the usefulness of ...
Callejas M A - - 2012
BACKGROUND: Involuntary craniofacial erythema, or blushing, due to autonomic dysfunction can be a cause of psychological distress. Although anecdotal reports have suggested that pharmacologic treatments or cognitive behavioral therapy can be used to treat the condition, no rigorous analyses of their efficacy have been reported. OBJECTIVES: To assess the efficacy ...
Himpens Jacques - - 2012
This retrospective study aimed to evaluate the long-term results of the laparoscopic Roux-en-Y gastric bypass (LRYGB) procedure performed at our department of bariatric surgery. The 126 consecutive patients treated by LRYGB between January 1, 2001 and December 31, 2002 were analyzed in August 2011. Seventy-seven patients (61.1 %), including 18 ...
Issa Nidal - - 2012
BACKGROUND: Diverticulosis of the right colon occurs in a small percentage of patients in Western countries. Clinical presentation of right-sided colon diverticulitis is indistinguishable from that of acute appendicitis, and the majority of patients undergo surgical intervention for presumed appendicitis. The liberal use of diagnostic radiological modalities whenever appendicitis was ...
Ong Marcus Eng Hock - - 2012
ABSTRACT: INTRODUCTION: It has been unclear if mechanical cardiopulmonary resuscitation (CPR) is a viable alternative to manual CPR. We aimed to compare resuscitation outcomes before and after switching from manual CPR to load-distributing band (LDB) CPR in a multi-center emergency department (ED) trial. METHODS: We conducted a phased, prospective cohort ...
López-García José S - - 2012
OBJECTIVE: To assess the effect of the use of containers with an adapted sterilizing filter on the contamination of autologous serum eyedrops. DESIGN: Prospective, consecutive, comparative, and randomized study. PARTICIPANTS: Thirty patients with Sjögren syndrome. METHODS: One hundred seventy-six autologous serum containers used in home therapy were studied; 48 of ...
Kumagai Hiroo - - 2012
Background: Our previous placebo-controlled, prospective, double-blind study demonstrated that a new opioid ĸ-receptor agonist, nalfurafine hydrochloride, effectively reduced treatment-resistant pruritus in 337 hemodialysis patients. Thus, we designed this study to evaluate prospectively the efficacy, safety, addiction liability, and pharmacokinetics of nalfurafine given orally for 1 year. Methods: This open-label study ...
Barreras Ferran - - 2012
Purpose: Catheter obstruction or patency inhibition of the venous access cannula is a frequently experienced problem in patients to whom intravenous (IV) solutions are administered. In this study we assessed the efficacy and safety of Securflux® a disposable device with a back-check valve to prevent reflux in IV infusion sets. ...
Oteo-Álvaro Angel - - 2012
Background and Objective: Hip and knee osteoarthritis is highly prevalent in the elderly, and the incidence is estimated to increase in the coming decades. Prior to surgery, symptomatic treatment, starting with non-pharmacological therapies, should be prescribed. Paracetamol (acetaminophen) is the recommended first pharmacological treatment for osteoarthritis. If paracetamol is ineffective, ...
Tamasauskas Arimantas - - 2012
BACKGROUND: Long-term dopamine agonist (DA) therapy is recommended as a first-line approach for the management of microprolactinomas. However, DA therapy may be poorly tolerated by some patients, and therefore some patients continue to prefer surgery over DA therapy. AIM: The aim of our study was to evaluate factors associated with ...
Hunter Christopher L - - 2012
OBJECTIVE: Exhaled end-tidal carbon dioxide (Etco(2)) concentration is associated with lactate levels in febrile patients. We assessed the association of Etco(2) with mortality and lactate levels in patients with suspected sepsis. METHODS: This was a prospective observational study. We enrolled 201 adult patients presenting with suspected infection and 2 or ...
Tam Dong T H DT University of Medicine and Pharmacy of Ho Chi Minh City, Viet - - 2012
Patients with dengue can experience a variety of serious complications including hypovolemic shock, thrombocytopenia, and bleeding. These problems occur as plasma viremia is resolving and are thought to be immunologically mediated. Early corticosteroid therapy may prevent the development of such complications but could also prolong viral clearance. We performed a ...
Sirak John H - - 2012
In accordance with the Cox-Maze paradigm, successful treatment of atrial fibrillation (AF) requires (1) complete posterior left atrial isolation, (2) elimination of corridors for perimitral reentry, (3) elimination of cardiac venous (superior vena cava and coronary sinus) arrhythmogenic foci, (4) complete autonomic denervation, and (5) occlusion or removal of the ...
Organ Michael - - 2012
BACKGROUND:: Patients who develop castration-resistant prostate cancer (CRPCa) typically continue on androgen deprivation therapy (ADT). Whether these patients need to remain on ADT has not been well studied. We conducted a multicenter randomized trial to compare an intermittent versus continuous approach to ADT in CRPCa patients. Overall survival, health-related quality ...
Ciccone Marco Matteo - - 2012
INTRODUCTION: Previous studies support the fact that extracorporeal shockwave (SW) induces angiogenesis and improves symptoms in patients affected by limb ischemia. The aim of this study was to evaluate the effects of SW therapy in patients with peripheral artery disease (PAD). METHODS: Twenty-two patients were enrolled in this study and ...
Jervis-Bardy Joshua - - 2012
OBJECTIVES/HYPOTHESIS: Chronic rhinosinusitis (CRS) recalcitrant to surgery is a frustrating clinical entity. Recently, mupirocin sinonasal rinses have been suggested as an efficacious treatment alternative in these patients where Staphylococuccus aureus infection is demonstrated. To our knowledge, how best to treat this S aureus reservoir has not been previously evaluated in ...
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