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Results 251 - 300 of 4724
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Scrivo Rossana - - 2012
Screening for latent tuberculosis infection (LTBI) prior to the prescribing of anti-TNF agents and monitoring for infection during treatment are recommended. The feasibility of novel screening tools, including QuantiFERON-TB Gold In-Tube (QFT-GIT), remains unclear in the setting of immunosuppression. The aim of this study was to evaluate the usefulness of ...
Callejas M A - - 2012
BACKGROUND: Involuntary craniofacial erythema, or blushing, due to autonomic dysfunction can be a cause of psychological distress. Although anecdotal reports have suggested that pharmacologic treatments or cognitive behavioral therapy can be used to treat the condition, no rigorous analyses of their efficacy have been reported. OBJECTIVES: To assess the efficacy ...
Himpens Jacques - - 2012
This retrospective study aimed to evaluate the long-term results of the laparoscopic Roux-en-Y gastric bypass (LRYGB) procedure performed at our department of bariatric surgery. The 126 consecutive patients treated by LRYGB between January 1, 2001 and December 31, 2002 were analyzed in August 2011. Seventy-seven patients (61.1 %), including 18 ...
Issa Nidal - - 2012
BACKGROUND: Diverticulosis of the right colon occurs in a small percentage of patients in Western countries. Clinical presentation of right-sided colon diverticulitis is indistinguishable from that of acute appendicitis, and the majority of patients undergo surgical intervention for presumed appendicitis. The liberal use of diagnostic radiological modalities whenever appendicitis was ...
Ong Marcus Eng Hock - - 2012
ABSTRACT: INTRODUCTION: It has been unclear if mechanical cardiopulmonary resuscitation (CPR) is a viable alternative to manual CPR. We aimed to compare resuscitation outcomes before and after switching from manual CPR to load-distributing band (LDB) CPR in a multi-center emergency department (ED) trial. METHODS: We conducted a phased, prospective cohort ...
López-García José S - - 2012
OBJECTIVE: To assess the effect of the use of containers with an adapted sterilizing filter on the contamination of autologous serum eyedrops. DESIGN: Prospective, consecutive, comparative, and randomized study. PARTICIPANTS: Thirty patients with Sjögren syndrome. METHODS: One hundred seventy-six autologous serum containers used in home therapy were studied; 48 of ...
Kumagai Hiroo - - 2012
Background: Our previous placebo-controlled, prospective, double-blind study demonstrated that a new opioid ĸ-receptor agonist, nalfurafine hydrochloride, effectively reduced treatment-resistant pruritus in 337 hemodialysis patients. Thus, we designed this study to evaluate prospectively the efficacy, safety, addiction liability, and pharmacokinetics of nalfurafine given orally for 1 year. Methods: This open-label study ...
Barreras Ferran - - 2012
Purpose: Catheter obstruction or patency inhibition of the venous access cannula is a frequently experienced problem in patients to whom intravenous (IV) solutions are administered. In this study we assessed the efficacy and safety of Securflux® a disposable device with a back-check valve to prevent reflux in IV infusion sets. ...
Oteo-Álvaro Angel - - 2012
Background and Objective: Hip and knee osteoarthritis is highly prevalent in the elderly, and the incidence is estimated to increase in the coming decades. Prior to surgery, symptomatic treatment, starting with non-pharmacological therapies, should be prescribed. Paracetamol (acetaminophen) is the recommended first pharmacological treatment for osteoarthritis. If paracetamol is ineffective, ...
Tamasauskas Arimantas - - 2012
BACKGROUND: Long-term dopamine agonist (DA) therapy is recommended as a first-line approach for the management of microprolactinomas. However, DA therapy may be poorly tolerated by some patients, and therefore some patients continue to prefer surgery over DA therapy. AIM: The aim of our study was to evaluate factors associated with ...
Hunter Christopher L - - 2012
OBJECTIVE: Exhaled end-tidal carbon dioxide (Etco(2)) concentration is associated with lactate levels in febrile patients. We assessed the association of Etco(2) with mortality and lactate levels in patients with suspected sepsis. METHODS: This was a prospective observational study. We enrolled 201 adult patients presenting with suspected infection and 2 or ...
Tam Dong T H DT University of Medicine and Pharmacy of Ho Chi Minh City, Viet - - 2012
Patients with dengue can experience a variety of serious complications including hypovolemic shock, thrombocytopenia, and bleeding. These problems occur as plasma viremia is resolving and are thought to be immunologically mediated. Early corticosteroid therapy may prevent the development of such complications but could also prolong viral clearance. We performed a ...
Sirak John H - - 2012
In accordance with the Cox-Maze paradigm, successful treatment of atrial fibrillation (AF) requires (1) complete posterior left atrial isolation, (2) elimination of corridors for perimitral reentry, (3) elimination of cardiac venous (superior vena cava and coronary sinus) arrhythmogenic foci, (4) complete autonomic denervation, and (5) occlusion or removal of the ...
Organ Michael - - 2012
BACKGROUND:: Patients who develop castration-resistant prostate cancer (CRPCa) typically continue on androgen deprivation therapy (ADT). Whether these patients need to remain on ADT has not been well studied. We conducted a multicenter randomized trial to compare an intermittent versus continuous approach to ADT in CRPCa patients. Overall survival, health-related quality ...
Ciccone Marco Matteo - - 2012
INTRODUCTION: Previous studies support the fact that extracorporeal shockwave (SW) induces angiogenesis and improves symptoms in patients affected by limb ischemia. The aim of this study was to evaluate the effects of SW therapy in patients with peripheral artery disease (PAD). METHODS: Twenty-two patients were enrolled in this study and ...
Jervis-Bardy Joshua - - 2012
OBJECTIVES/HYPOTHESIS: Chronic rhinosinusitis (CRS) recalcitrant to surgery is a frustrating clinical entity. Recently, mupirocin sinonasal rinses have been suggested as an efficacious treatment alternative in these patients where Staphylococuccus aureus infection is demonstrated. To our knowledge, how best to treat this S aureus reservoir has not been previously evaluated in ...
Sasajima Y - - 2012
OBJECTIVES: To preoperatively determine candidates at definitive risk of postoperative delirium (POD), we identified relevant factors in patients with arteriosclerosis obliterans who underwent bypass surgery. DESIGN: A prospective cohort study. PATIENTS AND METHODS: 299 patients (age ≥60 years) who underwent bypasses in 1995-2006 were enrolled. Cognitive impairment was assessed by ...
Gu Qiang - - 2012
Aim  To investigate the maternal homocysteine (Hcy), folate, vitamin B(12) and B(6) , and their relations to neural tube defects (NTDs). Methods 30 mothers of NTDs offspring and another 60 mothers of normal children were enrolled as the patient and control groups from Xinjiang, China from Jan 2008 to May ...
Kozma Chris M - - 2012
To examine opioid prescription claims before and after initiation of pregabalin in patients with a diagnosis of diabetic peripheral neuropathy (DPN). This retrospective analysis used a national commercial database of integrated inpatient, outpatient, and prescription claims to identify adults with a DPN diagnosis code within 360 days prior to the ...
Sanelli P C PC Departments of Radiology, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, New York 10065, USA. - - 2013
DCI is a serious complication following aneurysmal SAH and remains a leading cause of morbidity and mortality. Our aim was to evaluate CTP in aneurysmal SAH by using outcome measures of DCI. This was a retrospective study of consecutive patients with SAH enrolled in a prospective institutional review board-approved clinical ...
Kennedy Fiona - - 2012
To present the results of the nonrandomized arm of the Cervical Artery Dissection in Stroke Study (CADISS-NR) trial, comparing anticoagulation and antiplatelets for prevention of recurrent stroke after carotid and vertebral dissection, and perform a meta-analysis of these results with previously published studies comparing the 2 therapeutic strategies. A total ...
Abuchar Adriana - - 2012
Background: Etanercept has been used to treat chronic plaque psoriasis. Previously reported data demonstrated that some patients experienced secondary failure and frequently rotational-switch therapy is used. The re-treatment with etanercept as part of the rotational therapy could be considered as another safe and efficient therapeutic approach. Objective: To evaluate the ...
Baumann F - - 2012
The aim of this paper was to evaluate the efficacy of a novel 4-F compatible self-expanding Nitinol stent for the treatment of long femoro-popliteal obstructions. This retrospective analysis includes patients with femoro-popliteal obstructions ≥120 mm in length, treated with a novel Nitinol stent (Pulsar-18) between February 2010 and December 2011. ...
Elalfy Mohsen S - - 2012
Background: Surgery and intensive factor VIII (FVIII) replacement may be risk factors for development of inhibitors. Objective: To evaluate time and rate of inhibitor development postcircumcision over 12-month period, and to assess bleeding of children with severe hemophilia A after low-dose FVIII replacement and local hemostasis. Patients and Methods: Sixty-one ...
Nomura Osamu - - 2012
OBJECTIVES: Little is known about the relationship between prior treatment with antibiotics and delay of diagnosis and treatment in pediatric acute appendicitis (AA). We have defined a situation requiring more than 48 hours from the onset of symptoms to surgery in pediatric AA as "therapeutic delay." The aim of this ...
Davies Andrew R - - 2012
OBJECTIVE:: Current guidelines recommend enteral nutrition in critically ill adults; however, poor gastric motility often prevents nutritional targets being met. We hypothesized that early nasojejunal nutrition would improve the delivery of enteral nutrition. DESIGN:: Prospective, randomized, controlled trial. SETTING:: Seventeen multidisciplinary, closed, medical/surgical, intensive care units in Australia. PATIENTS:: One ...
Morton Ryan - - 2012
: A paucity of patients with ruptured basilar apex aneurysms have been analyzed with long-term clinical results. : Sixty-one consecutive ruptured basilar apex aneurysms from 2005 to 2011 were retrospectively reviewed. A team-oriented approach was used to decide treatment. Clipping was typically used in younger patients, those with a complex ...
Mohammadi Alireza Mohammad - - 2012
: Trigeminal neuralgia (TN) is relatively frequent in Multiple Sclerosis (MS) patients and procedural treatments are less effective than when used for classical TN. Outcomes from direct comparisons between different procedures for MS-related TN is lacking. In this study, initial pain-free rates (IPFR), duration of pain-free intervals (PFI) and associated ...
Stefanovic Vedran - - 2012
Objective. To analyse the effectiveness of intravenous sulprostone infusion for the treatment of retained placenta without massive primary hemorrhage among patients at a university hospital over a three-year period. Design. Retrospective observational study. Setting. University teaching hospital. Population. 126 consecutive women with placental retention and intravenous sulprostone infusion as primary ...
Düzgün Irem - - 2012
This study aims to compare the efficacy of manual therapy in the frozen shoulder patients with or without diabetes mellitus. Between May 2006 and January 2008, 50 patients (10 males, 40 females; mean age 52±10 years; range 40 to 65 years) orthopedic surgeons referred to the Sports Physiotherapy Unit were ...
Thaci Bart - - 2012
: Patient-filled questionnaires, such as Oswestry Disability Index (ODI) or Neck Disability Index (NDI) have become the mainstay in the evaluation of treatment outcomes in degenerative spine disease (DSD), replacing result-reporting by surgeons. In this study we set to compare patients' and surgeons' assessment of spine treatment outcome in a ...
Slottosch Ingo - - 2012
BACKGROUND: We assessed the short-term outcomes and predictors of 30-d mortality in patients requiring temporary, peripheral extracorporeal membrane oxygenation (ECMO) for postcardiotomy cardiac failure. METHODS: The data were retrospectively obtained using our institutional patient database. All patients who had received peripheral ECMO support after surgery for acquired heart disease from ...
Wang Jin-Hu - - 2012
The management of the contralateral asymptomatic side when a child with initial unilateral inguinal hernia undergoes herniorrhaphy continues to be controversial. Age less than 6 months at initial herniorrhaphy is considered as a high risk factor of the occurrence of metachronous contralateral inguinal hernia (MCIH). We performed herniorraphy for patients ...
Oliveira Rosmari A R A - - 2012
Evaluate the Glasgow outcome scale (GOS) at discharge (GOS-HD) as a prognostic indicator in patients with traumatic brain injury (TBI). Retrospective data were collected of 45 patients, with Glasgow coma scale <8, age 25±10 years, 36 men, from medical records. Later, at home visit, two measures were scored: GOS-HD (according ...
Mistry Rajesh C - - 2012
HYPOTHESIS Controversy exists over the need for prolonged nasogastric decompression after esophagectomy. We hypothesized that early removal of the nasogastric tube would not adversely affect major pulmonary complications and anastomotic leak rates. DESIGN Single-center, parallel-group, open-label, randomized (1:1) trial. SETTING A tertiary referral cancer center with high esophagectomy volume. PATIENTS ...
Eisner Mark D - - 2012
Background. Asthma guidelines emphasize the importance of achieving and maintaining asthma control; however, many patients with moderate to severe asthma fail to achieve adequate control. Objective. This 2-year interim analysis evaluated the longitudinal effects of omalizumab on asthma control in patients treated in real-world clinical practice settings. Methods. EXCELS is ...
Connolly M P - - 2012
Background: In this study we investigate the costs and benefits of topical mesalazine combined with oral mesalazine therapy for active ulcerative colitis (UC), and once daily (OD ) mesalazine 2 grams versus twice daily (BID ) for maintaining UC remission. Methods: Two decision analytic models were constructed to evaluate treatment ...
Ortiz Héctor - - 2012
: Sacral nerve stimulation has been reported as an effective treatment for constipation. : This study aimed to evaluate the therapeutic efficacy of permanent sacral nerve stimulation on the treatment of idiopathic constipation resistant to medical and behavioral management over a median follow-up period of 25.6 (range, 6-96) months. : ...
Dudley Roy W R - - 2012
: In spastic cerebral palsy (CP), damage to the immature brain is non-progressive, but the clinical expression of the disorder changes over time along with the growth and development of the child. Large-scale, population based studies describing the natural history of gross motor development in spastic CP have indicated that ...
Hitchon Patrick W - - 2012
: Choosing the optimal treatment modality for refractory trigeminal neuralgia (TN) is multifactorial, and has not been well defined in the literature. In this review we specifically explore the role of three factors in determining the treatment modality: age, recurrence rate, and cost. : Retrospective chart review of patients who ...
Melton J T K - - 2012
A consecutive series of patients with a hydroxyapatite-coated uncemented total knee replacement (TKR) performed by a single surgeon between 1992 and 1995 was analysed. All patients were invited for clinical review and radiological assessment. Revision for aseptic loosening was the primary outcome. Assessment was based on the Knee Society clinical ...
Lucas Donald J - - 2012
Retrievable IVC filters (R-IVCF) are associated with multiple complications, including filter migration and deep venous thrombosis. Unfortunately, most series of R-IVCF show low retrieval rates, often due to loss to follow-up. This study demonstrates that actively tracking R-IVCF improves retrieval. Trauma patients at one institution with R-IVCF placed between January ...
Mundis Gregory - - 2012
: This study analyzes the prevalence and risk factors for the development of PJK following lumbar PSO. The hypothesis was that PJK would develop early in the postoperative period at high rates in this population undergoing dramatic sagittal plane realignment, and that risk factors based on baseline and follow-up radiographs ...
Patil Arun-Angelo - - 2012
: The conventional procedure of hippocampectomy can impair memory. Furthermore, the hippocampus is the main source of stem cells. On the other hand, multiple hippocampal transection (MHT) can disrupt seizure circuits without loss of function or stem cells. In this presentation therefore, the authors will present long term outcomes in ...
Gourdine-Shaw Monique C - - 2012
Certain complex foot deformities can be corrected surgically with a U-osteotomy. This osteotomy is indicated for patients with a uniform deformity of the entire foot relative to the tibia, preexisting stiffness and/or fusion of the subtalar joint, and a pain-free ankle joint. The goal is to create a plantigrade foot ...
Choy-Shan Alana - - 2012
The purpose of this study was to assess the impact of rosiglitazone on survival in patients with diabetes mellitus (DM) and coronary artery disease (CAD). We carried out a drug-exposure analysis in 801 patients with DM and CAD in a cardiac catheterization laboratory registry (490 patients treated with a percutaneous ...
Chalouhi Nohra - - 2012
OBJECTIVE: Aneurysmal subarachnoid hemorrhage (SAH) is relatively uncommon in young adults. There is a paucity of data pertaining to the management of aneurysmal SAH in young patients, especially with endovascular therapy. METHODS: We reviewed all SAH patients under the age of 35 years treated at Jefferson Hospital for Neuroscience, Philadelphia, ...
Choi Wilson W - - 2012
A sutureless ward reduction (SWR) protocol was implemented in the neonatal intensive care unit of a tertiary level hospital in 1999. Although the short-term outcomes associated with SWR have been documented, the long-term outcomes are unknown. Retrospective data were collected from the medical records of all neonates with gastroschisis from ...
Charalambous Charalambos P - - 2012
Early posttraumatic elbow contractures may be treated with a combination of manipulation with the patient under anesthesia followed by bracing.Extrinsic contractures of the elbow may be treated with open or arthroscopic release, whereas intrinsic and combined contractures may require tissue release as well as partial or total arthroplasty.
Fehlings Michael G - - 2012
: While cervical spondylotic myelopathy (CSM) is the most common cause of spinal cord impairment worldwide, little is known regarding international variations in clinical presentation, management and outcomes of this condition. To address this key issue, we undertook a prospective multicenter study of CSM patients undergoing surgical treatment. : 486 ...
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