Search Results
Results 451 - 500 of 4700
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Nalamachu Srinivas R - - 2012
CONTEXT: The efficacy and tolerability of once-daily hydromorphone extended release (ER) (OROS(®) hydromorphone ER, Exalgo(®), Mallinckrodt Brand Pharmaceuticals, Inc., Hazelwood, MO) in patients with chronic cancer and noncancer pain have been reported in previous studies. OBJECTIVES: The objective of this analysis was to assess the pooled safety data of OROS ...
Lattimer Christopher R - - 2012
BACKGROUND: Pulsatile flow in deep, perforating veins and varicose veins (VVs) has been described previously to support a hypothesis of arterio-venous (A-V) fistulae in the pathogenesis of VVs. Its presence has also been suggested as a cause of failure of VV treatments. However, A-V communications have never been adequately visualized ...
Fernandez-Nebro A - - 2012
Objective: This study aimed to investigate the effectiveness and safety of single and repeated courses of rituximab in patients with refractory lupus. Methods: LESIMAB is a multicenter, retrospective, longitudinal study of lupus patients who have not responded to standard therapy and have been treated with rituximab. Response rates at six ...
Lin Yiyun - - 2012
BACKGROUND: Constrictive pericarditis is a rare and disabling disease that can result in chronic fibrous thickening of the pericardium. Prompt treatment of constrictive pericarditis is necessary to limit morbidity and mortality. METHODS: We analyzed the clinical details of 51 constrictive pericarditis patients who underwent surgery from January 2005 to December ...
Albarel Frédérique - - 2012
Given the new therapeutic options in acromegaly, it seemed important to evaluate the outcome of operated acromegalic patients today. OBJECTIVE: To analyze the characteristics and short- and long-term surgical outcome of patients who underwent transsphenoidal surgery for a growth hormone (GH)-secreting adenoma in our center and to determine predictive factors ...
Boissonneault Adam - - 2012
PURPOSE: Anterior cruciate ligament deficiency (ACLD) has been considered a contraindication for Oxford unicompartmental knee arthroplasty (UKA) because of the reported higher incidence of failure when implanted in ACLD knees. However, given the potential advantages of UKA over total knee arthroplasty (TKA), we have performed UKA in a limited number ...
Barski D - - 2012
PURPOSE: To retrospectively analyse the intermediate-term outcome of holmium laser ablation of the prostate (HoLAP) of up to 4 years postoperatively in one of the largest series and to define the selection criteria for patients who benefit from potentially lower complications associated with HoLAP. METHODS: Between June 2006 and November 2010, ...
Cadranel J - - 2012
Early evidence suggests the efficacy of voriconazole for chronic pulmonary aspergillosis (CPA). We conducted a prospective, open, multicenter trial to evaluate the efficacy and safety of voriconazole for proven CPA in minimally or non-immunocompromised patients. Patients had CPA confirmed by chest computed tomography (CT) and/or endoscopy, positive Aspergillus culture from ...
Isik Nejat - - 2013
The use of drains in the treatment of syringomyelia has a simple and immediate appeal. Syringopleural shunting in syringomyelia has produced good short-term results, but limited information is available on long-term effects. We analyzed the complications and long-term outcomes after syringopleural shunting for syringomyelia. Fourthy-four patients with large-sized syringomyelia underwent ...
Di Biase Luigi - - 2012
This study investigated the impact on recurrences of 2 different substrate approaches for the treatment of these arrhythmias. Catheter ablation of electrical storms (ES) for ventricular arrhythmias (VAs) has shown moderate long-term efficacy in patients with ischemic cardiomyopathy. Ninety-two consecutive patients (81% male, age 62 ± 13 years) with ischemic ...
Shim Jaemin - - 2012
BACKGROUND: Although radiofrequency catheter ablation (RFCA) for atrial fibrillation (AF) is an effective rhythm control strategy, there is a substantial amount of recurrence. We explored the predictors of AF recurrence after RFCA with consistent ablation strategy. METHODS AND RESULTS: This study included 575 patients (77% male, 56±11years old) with AF ...
Gupta Punkaj - - 2012
BACKGROUND: Identify incidence, etiology, and predictors of extubation failure in neonates and infants who underwent Norwood operation with either a modified Blalock-Taussig shunt (mBTS) or a Sano shunt at a single tertiary care, academic children's hospital. METHODS: Extubation failure for our study was defined as reintubation within 96 hours after ...
Seguy David - - 2012
BACKGROUND: Parenteral nutrition (PN) is still widely preferred to enteral nutrition (EN) in malnourished patients undergoing allogeneic stem-cell transplantation (allo-SCT) after myeloablative conditioning (MAC). The purpose was to determine whether EN improves early outcome after MAC allo-SCT. METHODS: Early outcome was prospectively assessed in patients undergoing MAC allo-SCT. A total ...
Pena Miriam González - - 2012
OBJECTIVES: Middle ear effusion (MEE) is rare among adults but has a higher incidence among Intensive Care Unit (ICU) patients. The aim of this study was to analyze the effect of nasogastric tube on MEE and assess other predisposing factors. METHODS: Prospective observational study, carrying out an otoscopic examination and ...
Holmlund Anders - - 2012
Twenty-two patients with chronic arthritis and ankylosis of the temporomandibular joint (TMJ) were treated by resection of the condyle with osteoarthrectomy and interposition with a temporalis muscle flap. We compared them with 14 patients who were treated by condylectomy and osteoarthrectomy alone. All patients were evaluated prospectively. Most patients had ...
Nakada Teruhiro - - 2012
Objective: To assess the safety and efficacy of hyperbaric oxygen (HBO) for treating radiation cystitis a long-term follow-up study was done in patients with prostate cancer, the second most common malignancy in Japan. Patients and Methods: A total of 38 patients at an age of 68 ± 8 years with ...
Banu Tahmina - - 2012
Introduction The purpose of this study is to describe the experience of managing leech infestation in lower urinary tract from a tropical country.Materials and Methods Medical records (January 2002 to December 2010) of children with history of leech infestation in the urinary system, admitted in the Department of Pediatric Surgery, ...
Elshoff Lydia - - 2012
Purpose:  In the presurgical evaluation of children and juvenile patients with refractory focal epilepsy, the main challenge is to localize the point of seizure onset as precisely as possible. We compared results of the conventional electroencephalography-functional magnetic resonance imaging (EEG-fMRI) analysis with those obtained with a newly developed method using ...
Fragomen Austin T - - 2012
Ankle arthrodesis may be achieved using the Ilizarov method. Comorbidities, such as diabetes, Charcot neuroarthropathy, osteomyelitis, leg length discrepancy, and smoking, can make an ankle fusion complex and may be associated with lower rates of healing. We asked if (1) smoking and other comorbidities led to lower fusion rates, (2) ...
Ionescu-Ittu Raluca - - 2012
Controversy continues concerning the choice of rhythm control vs rate control treatment strategies for atrial fibrillation (AF). A recent clinical trial showed no difference in 5-year mortality between the 2 treatments. We aimed to determine whether the 2 strategies have similar effectiveness when applied to a general population of patients ...
Peukert Nadine - - 2012
Background: Fractionated photothermolysis (FP) is used for the treatment of facial wrinkles. Objectives: Investigation of effects of different FP treatment parameters in the treatment of facial wrinkles. Patients and methods: In a randomized split-face controlled study 11 patients received 3 FP sessions in 4-week intervals. Keeping the total energy input ...
Said Samir M - - 2012
BACKGROUND: Dronedarone is a new antiarrhythmic agent that has only recently been approved for the therapy of atrial fibrillation (AF). Results regarding a broader spectrum of patients and experience accumulated in clinical practice are still very scarce. Therefore, we prospectively investigated the efficacy and tolerance of dronedarone in a real ...
Dos Santos Juliana Magalhães Reis - - 2012
OBJECTIVE:: To describe the results of endoscopic secondary prophylaxis, alone or in combination with propranolol, used to prevent upper gastrointestinal bleeding (UGIB) in children and adolescents with esophageal varices. METHODS:: This observational study followed 43 patients under 18 years of age who received secondary prophylaxis between August 2001 and December ...
Baker Richard P - - 2012
We identified 45 knees in 42 patients who had an isolated tibial insert exchange for a failed primary knee arthroplasty with a minimum of 2 years of follow-up. The mean age at revision was 68 years, and the mean time to revision was 80 months. Thirty patients completed follow-up questionnaires ...
Artz Neil N Musculoskeletal Research Unit, University of Bristol, Bristol, UK. - - 2013
Total hip replacement (THR) and total knee replacement (TKR) are two common elective orthopaedic procedures, and the provision of physiotherapy for patients after discharge is variable, with evidence for best practice remaining uncertain. To determine the standard physiotherapy service offered to patients following discharge after THR and TKR. A telephone ...
Zibetti Maurizio - - 2012
Duodenal infusion of levodopa/carbidopa gel (Duodopa) is an effective treatment option for advanced Parkinson's disease (PD). Long-term clinical experience up to 16 years suggests that the safety of this procedure is acceptable, while several observational studies showed that Duodopa reduces motor fluctuations and dyskinesias improving patients' quality of life (QoL). The ...
Urso Emanuele D L - - 2012
BACKGROUND: Currently, no guidelines exist for the treatment of patients with multiple colorectal adenomas (MCRAs) (>10 but <100 synchronous nondiminutive polyps of the large bowel). This retrospective study aimed to investigate the clinical and molecular factors related to different treatments for MCRAs. METHODS: Patients with MCRAs were consecutively enrolled from ...
Williamson J Blair - - 2012
Spiral enteroscopy can be safe and effective in the short term for evaluation of obscure GI bleeding, but long-term data are lacking. To assess the long-term clinical outcomes after deep small-bowel spiral enteroscopy performed for obscure GI bleeding. Prospective cohort study. Academic referral center. This study included 78 patients who ...
Kawashiri Shin-Ya - - 2012
We introduced abatacept (ABT) in a very early rheumatoid arthritis (RA) patient with active tenosynovitis of hands defined by musculoskeletal ultrasonography (MSKUS). MSKUS-proven tenosynovitis remarkably improved at 2 months in spite of clinical exacerbation, followed by clinical remission at 5 months. MSKUS abnormalities also disappeared. Although ABT was discontinued due to an ...
Zarraga Ignatius Gerardo E - - 2012
BACKGROUND: -Previous studies have suggested that aldosterone blockade can reduce the incidence of ventricular tachycardia (VT) or ventricular fibrillation (VF) in patients with heart failure (HF). The SPIronolactone to Reduce ICD Therapy (SPIRIT) trial was designed to test the hypothesis that spironolactone reduces the incidence of VT/VF in patients with ...
Rolf Sascha - - 2012
BACKGROUND: -We describe a novel fluoroscopy co-registered 4D catheter tracking technology (MGT) used for treatment of patients with atrial fibrillation (AF). The aim of the study was to investigate (i) feasibility of non-fluoroscopic catheter manipulation within dynamic left atrial chamber models, (ii) integration of the technology into an established electroanatomical ...
Kim Hee Jin - - 2012
Background: Delayed facial palsy (DFP) after microvascular decompression (MVD) in patients with hemifacial spasm (HFS) is not uncommon, but the cause remains unknown. Objectives: To assess whether intraoperative electromyography (EMG) and brainstem auditory evoked potential (BAEP) can predict DFP after MVD. Methods: Between September 2009 and February 2011 we examined ...
Sen Keiiku - - 2012
Aim:  We have examined the risk factors and management processes of the persistent occiput posterior (pOP) position by analyzing medical records from our hospital. Material and Methods:  Medical records and delivery notes from January 2007 to December 2009 were reviewed and 103 patients were identified as having the pOP position ...
Bakker-Dyos Josh - - 2012
We evaluated the use of a cemented constrained acetabular component to treat recurrent or potential instability after hip replacement. Over a seven year period, 109 patients who had undergone 110 operations were identified from hospital records. Patients were reviewed based on clinical and radiological follow-up. Post-operative function and quality of ...
Thompson Eric M - - 2012
Object Vagus nerve stimulation (VNS) is approved by the FDA for the treatment of partial epilepsy in patients older than 12 years. Authors of the current study performed a large retrospective analysis and comparison of VNS outcomes in children with an age ≥ and < 12 years, including those with ...
McGowan Meghan L - - 2012
Objective To analyze the association between concentration, as measured by the Interactive Metronome, and a prolonged second stage of labor in nulliparous patients.Study Design From September 2008 to November 2009, nulliparous women at ≥34 weeks' gestation who were planning to use an epidural were asked to perform a 1-minute Interactive ...
Delgado Acosta F - - 2012
OBJECTIVES: To evaluate the recanalization rate and clinical outcome three months after endovascular treatment for vertebrobasilar occlusion before the placement of stentrievers. MATERIAL AND METHODS: We reviewed all cases of basilar thrombosis treated with endovascular techniques at our center. We reviewed the clinical outcomes with the main objective of determining ...
van Dussen Laura - - 2012
This paper describes the effects of a switch to velaglucerase alfa in a group of adult patients with type 1 Gaucher disease all of whom had previously had their dose reduced as a consequence of the worldwide imiglucerase shortage.Thirty-two patients from two large European Gaucher centers switched to treatment with ...
Lim Alan A - - 2012
ABSTRACT: Patients with congenital craniofacial malformations present with complex challenges for reconstruction. Successful management requires individualized treatment often involving rebuilding the facial skeleton de novo, as well as correcting the overlying soft-tissue deficiencies in the final stages. At the University of California, Los Angeles (UCLA) Craniofacial Clinic, serial autologous fat ...
Harwin Steven F - - 2012
Total knee arthroplasty can be challenging in Jehovah's Witnesses, as these patients do not accept blood transfusions. We reported our experiences with a special blood management protocol for these patients who underwent total knee arthroplasty. There were 124 self-reported Jehovah's Witnesses who had a mean age of 64 years and ...
Erkapic Damir - - 2012
AimsPrevention of sudden cardiac death by means of the implantable cardioverter/defibrillator (ICD) is considered to be a lifelong therapy. However, it is still unresolved if patients who never experienced an appropriate ICD intervention during generator longevity really need to undergo device replacement.Methods and resultsThe INSURE trial was a multicentre prospective ...
Meno H - - 2012
Many patients with hypertension have difficulty achieving their target blood pressure (BP). Therefore combination therapy, for example with an angiotensin II receptor blocker (ARB) and a diuretic, may be recommended. We previously evaluated the efficacy and safety of losartan (LOS) 50 mg - hydrochlorothiazide (HCTZ) 12.5 mg, as well as ...
Kapoor Akshay - - 2012
OBJECTIVES: To evaluate the markers of lymphocyte activation (sIL-2R, IL-6 and TNF α) in the peripheral blood of newly diagnosed patients with celiac disease (CD) and patients with CD on Gluten free diet (GFD) for at least 2 y. The markers were correlated with conventional serological tests Anti-tissue transglutaminase (Anti-TTG) used ...
Rochlin Danielle H - - 2012
BACKGROUND: Surgical treatment for neurogenic thoracic outlet syndrome does not always yield successful outcomes. The purpose of this study was to describe patients with unresolved, recurrent, and/or contralateral symptoms following first rib resection and scalenectomy (FRRS) and to determine therapies for improving their outcomes. METHODS: Data on 161 neurogenic thoracic ...
Ozkan Ugur - - 2012
PURPOSE: We aimed to assess the degree of improvement in chronic venous disease-related symptoms after endovenous laser ablation (EVLA) for saphenous vein insufficiency. MATERIALS AND METHODS: The study was conducted as a single-center, single-arm prospective cohort study. The series was comprised of 55 limbs of 38 patients (24 [63%] females, ...
Lennert Barb - - 2012
Seizures are a hallmark manifestation of tuberous sclerosis complex, yet data characterizing resource utilization are lacking. This retrospective chart review was performed to assess the economic burden of tuberous sclerosis complex with neurologic manifestations. Demographic and resource utilization data were collected for 95 patients for up to 5 years after ...
Mikolajczak S - - 2012
Cidofovir is an antiviral agent used in the therapy of recurrent respiratory papillomatosis (RRP). In this study, we hypothesized that cidofovir is effective in decreasing the viral load of human papillomavirus (HPV). We established a type specific real-time PCR and measured HPV DNA loads. The course of viral load of ...
Boyd Scott B SB Department of Oral and Maxillofacial Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232-2103, USA. - - 2013
To present a new measurement instrument, the Effectiveness of Treatment Apnea-Hypopnea Index (ET-AHI), which the authors developed to determine an estimate of the therapeutic control of obstructive sleep apnea (OSA). The authors retrospectively evaluated a cohort of patients with OSA who initially attempted to use continuous positive airway pressure (CPAP) ...
Mbuba Caroline K CK KEMRI/Wellcome Trust Research Programme, Centre for Geographic Medicine Research (Coast), Kilifi, - - 2012
Many people with epilepsy in low-income countries do not receive appropriate biomedical treatment. This epilepsy treatment gap might be caused by patients not seeking biomedical treatment or not adhering to prescribed antiepileptic drugs (AEDs). We measured the prevalence of and investigated risk factors for the epilepsy treatment gap in rural ...
Morschhauser F - - 2012
BackgroundThis study explored the efficacy and safety of rituximab as treatment of clinical or molecular residual disease after autologous stem-cell transplantation (ASCT) in follicular lymphoma (FL).Patients and methodsForty patients with CD20+ FL and clinically (group A, n = 14) or clono-specific PCR-detectable (group B, n = 25) residual disease persisting 3 months after ASCT ...
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