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Sobaniec Stefan - - 2013
The study objective was clinical assessment of the efficacy of photodynamic therapy (PDT) in the treatment of oral lichen planus (OLP). There were 23 patients aged 31-82 included in the study with oral lichen planus diagnosed clinically and histopathologically. In all patients photodynamic therapy was performed with the use of ...
Shousha Mootaz M University of Alexandria, Alexandria, Egypt. - - 2012
Anterior cervical decompression and fusion is a well-established procedure for the treatment of cervical spinal canal stenosis. In this study, we evaluated the necessity of spinal instrumentation after four-level anterior cervical decompression and cage fusion. From January 2006 until August 2008, 25 patients (8 females and 17 males) (mean age ...
Hassan A E - - 2012
BACKGROUND AND PURPOSE:Endovascular treatment for acute ischemic stroke consists of various mechanical and pharmacologic modalities used for recanalization of arterial occlusions. We performed this study to determine the relationship among procedure time, recanalization, and clinical outcomes in patients with acute ischemic stroke undergoing endovascular treatment.MATERIALS AND METHODS:We analyzed data from ...
Cole Brian J - - 2012
BACKGROUND:This is an analysis of the prospective Study of the Treatment of Articular Repair (STAR) to evaluate the effectiveness of autologous chondrocyte implantation (ACI) in a subset of adult patients with osteochondritis dissecans (OCD) knee lesions. HYPOTHESIS:Autologous chondrocyte implantation can improve clinical outcomes in patients with at least 1 chronic ...
Haneya Assad - - 2012
BACKGROUND: Cardiopulmonary resuscitation (CPR) using extracorporeal life support (ECLS) system has been successfully used to support patients with in- and out-of-hospital cardiac arrest (IHCA, OHCA) when conventional measures have failed. The purpose of the current study is to report on our experience with extracorporeal CPR in non-postcardiotomy patients. METHODS: We ...
Baudry Camille - - 2012
CONTEXT: Alternatives to transsphenoidal pituitary surgery may be required in Cushing's disease (CD), as a first- or second-line treatment. Mitotane is a potent anti cortisolic but has been rarely investigated in the treatment of CD. OBJECTIVE: Evaluation of the efficacy and tolerance of mitotane in CD patients. DESIGN AND SETTING: ...
Hoashi Takaya - - 2012
BACKGROUND: We aimed to reveal late clinical features of patients with pulmonary atresia with intact ventricular septum (PA/IVS) or critical pulmonary stenosis (cPS) after biventricular repair (BVR) based on preoperative right ventricular (RV) end-diastolic volume (RVEDV) findings. METHODS: Since 1985, 23 of 73 patients with PA/IVS (n = 22) or ...
Shirakabe Akihiro - - 2012
BACKGROUND AND PURPOSE: The role of an arterial blood gas analysis in acute heart failure (AHF) remains unclear. The acid-base balance could help to treat AHF, and it might help to distinguish different types of AHF, while it might be associated with the AHF prognosis. The present study was conducted ...
Berger Julien - - 2012
We evaluated the morbidity of nephrectomy in patients older than age 80 years. Between June 2002 and March 2011, 2,530 patients underwent surgery for renal tumor at 5 French academic centers. Of these patients 180 (7.1%) were age 80 years or older, including 22 (12%) and 158 (88%) who underwent ...
Soize S - - 2012
BACKGROUND AND PURPOSE:The best approach between general anesthesia and conscious sedation to perform mechanical thrombectomy remains unknown. The goal of our study was to evaluate the feasibility, safety, and efficacy of mechanical thrombectomy under conscious sedation in patients with acute ischemic stroke, using the Solitaire FR device, in a prospective, ...
Szanyi Jana - - 2012
OBJECTIVE: The aim of this pilot study was to evaluate the efficacy of visual evoked potentials (VEPs) in the monitoring of visual function during a high-dose intravenous steroid pulse therapy and apheresis treatment of severe Graves' ophthalmopathy (GO). Patients and Research Design: Nine patients with severe and active GO were ...
Zitzmann Michael - - 2012
Introduction.  Morbidity/mortality is higher in men with below-normal serum testosterone. Restoring testosterone to normal is beneficial. Aim.  Assessment of safety and effectiveness of injectable long-acting testosterone undecanoate (TU) in hypogonadal men in daily clinical practice. Methods.  An international, multicenter, one-arm, prospective observational study in 23 countries. Main Outcome Measures.  Parameters ...
Pong Amanda W - - 2012
Purpose:  Glut 1 deficiency syndrome (DS) is defined by hypoglycorrhachia with normoglycemia, acquired microcephaly, episodic movements, and epilepsy refractory to standard antiepileptic drugs (AEDs). Gold standard treatment is the ketogenic diet (KD), which provides ketones to treat neuroglycopenia. Our purpose is (1) to describe epilepsy phenotypes in a large Glut ...
Omokawa Shohei - - 2012
We evaluated the responsiveness of patient-derived questionnaires and physical findings in evaluating recovery after treatment of ulnocarpal abutment syndrome. Patients were assessed at their initial visit to our clinic and again 3 months after the treatment. At each visit, patients completed a Short Form-36, the Japanese Society for Surgery of ...
Jeromel Miran - - 2012
BACKGROUND: Endovascular mechanical revascularization (thrombectomy) is an increasingly used method for intracranial large vessel recanalization in acute stroke. The purpose of the study was to analyze the recanalization rate, clinical outcome, and complication rate in our stroke patients treated with mechanical revascularization. METHODS: A total of 57 patients with large ...
Kanzaki Takeyuki - - 2012
To assess the long-term safety and efficacy of tacrolimus (TAC) used in combination with oral methotrexate (MTX) in patients with rheumatoid arthritis (RA) whose disease remains active despite treatment with MTX alone. The clinical courses of 24 RA patients who received TAC added to MTX from a single center were ...
Koivusalo A I - - 2012
BACKGROUND AND AIM: Paediatric rectal prolapse (RP) is rarely a diagnostic problem and resolves often spontaneously. We studied whether the assessment of recurrent RP (RP), postoperative relapsed RP (RRP) or anorectal discomfort without RP (ARD) benefits from dynamic defecography (DD) and describe DD findings in relation with outcome. PATIENTS AND ...
Erdag Mehmet Ali - - 2012
The objective of this study is to establish the role of risk factors in the etiology of pharyngocutaneous fistula formation after total laryngectomy. A retrospective study was performed for patient, disease and treatment-related factors, and also factors related to pathology specimen. Logistic regression analysis revealed that fistula development ratio was ...
Fischer-Levancini C - - 2012
INTRODUCTION: Nail involvement is common in psoriasis and has a considerable impact on patient quality of life. Its clinical presentation depends on which part of the nail is affected: the bed or the matrix. Fifty percent of patients report associated pain. In this study, we analyzed the safety and effectiveness ...
Goldberg Ythan H - - 2012
Background: Despite the 2008 revision of a previously issued black box warning of the US Food and Drug Administration against the use of perflutren ultrasound contrast agents, the warning still reports fatalities having occurred following their administration. We sought to assess 1-day mortality associated with contrast use across a wide ...
Rogers Lindsay S - - 2012
The aim of this study was to evaluate Fontan peri-operative outcomes for 771 consecutive patients. Since the initial description by Fontan, mortality associated with the Fontan operation has declined substantially. However, postoperative effusions remain a significant challenge. Effusions are a key determinant of postoperative length-of-stay and have been shown to ...
Wolf Brian R - - 2012
Total hip arthroplasty is a common surgical procedure, but little is known about longitudinal trends in associated adverse outcomes. Our objective was to describe long-term trends in demographics, comorbidities, and adverse outcomes for older patients who underwent primary and revision total hip arthroplasty. We identified a retrospective, observational cohort of ...
Ahmed Mustafa I MI Department of Medicine and Cardiovascular Disease, University of Alabama, Birmingham, AL, - - 2012
The purpose of the study was to evaluate the effect of long-term β(1)-aderergic receptor (AR) blockade on left ventricular (LV) remodeling and function in patients with chronic, isolated, degenerative mitral regurgitation (MR). Isolated MR currently has no proven therapy that attenuates LV remodeling or preserves systolic function. Thirty-eight asymptomatic subjects ...
Sabatowski Rainer R Comprehensive Pain Center (USC), University Hospital Carl Gustav Carus, Dresden, Germany. - - 2012
Prospective evaluation of the long-term efficacy and safety of the 5% lidocaine medicated plaster in patients with post-herpetic neuralgia (PHN). Patients with persisting pain for ≥3 months after acute herpes zoster and a baseline pain intensity of at least 4 on an 11-point numerical rating scale (NRS 0-10) were treated ...
Cetin Mustafa - - 2012
OBJECTIVE: Fragmented QRS complexes (fQRS) are defined as various RSR' patterns in 2 contiguous leads corresponding to a major coronary artery territory. Although the reason of association between fQRS and cardiac events was documented as cardiac fibrosis, the predictive role of fQRS was not studied for postoperative atrial fibrillation (POAF) ...
Fritz12 Jason S - - 2012
ABSTRACT RATIONALE: Six-minute walk distance (6MWD) and brain natriuretic peptide (BNP) levels at baseline and after initiation of treatment have been associated with survival in patients with pulmonary arterial hypertension (PAH). OBJECTIVES: To determine the individual and additive ability of pre- and post-treatment 6MWD and BNP to discriminate 2-year survival ...
Iborra-Moltó Carmelo - - 2012
Introduction: Studies of adherence to fluid restriction show high variability in prevalence data, as different methods of measuring IWG (interdialysis weight gain) and cut-off criteria are used. Objectives: To describe the prevalence of adherence to fluid restriction using daily IWG (criterion:&nbsp;&le;1Kg) and daily IWG adjusted for dry weight (DW) (cut-off ...
Singh Ajay K - - 2012
QUESTIONS Is volume supplementation using 24-hour sodium chloride better than 7-hour sodium bicarbonate for preventing contrast-induced nephropathy (CIN)? Is short-term sodium bicarbonate noninferior to 7-hour sodium bicarbonate? METHODS DESIGN Randomized controlled trial. ClinicalTrials.gov NCT00130598. ALLOCATION Unclear allocation concealment.* BLINDING Unblinded.* FOLLOW-UP PERIOD 48 hours and 90 days. SETTING 3 centers ...
Switzer Jeffrey A - - 2012
BACKGROUND AND PURPOSE: The effectiveness of prothrombin complex concentrate (PCC) products available in the United States that contain low levels of factor VII (3-factor PCC) has not been tested. The purpose of this study was to review our experience with 3-factor PCC (Profilnine) in the setting of warfarin-associated intracranial hemorrhage ...
Du Yi - - 2012
Bilateral acute optic neuritis (AON) is rare in adults in Western countries, but is relatively common in Asian populations. We aimed to document clinical features in Chinese patients with bilateral AON, and to identify factors that are predictive of visual acuity outcome. We reviewed 41 patients (23 males, 18 females; ...
Yukizawa Yohei - - 2012
Fondaparinux (FPX), a selective inhibitor of factor Xa, is widely used for the prophylaxis of venous thromboembolism (VTE) after total joint arthroplasty. However, the association between plasma FPX concentration and adverse events and the occurrence of VTE has not been clarified thus far. We aimed to prospectively evaluate these associations ...
Archdeacon Michael T - - 2012
OBJECTIVE:: To present clinical, radiographic and functional outcomes of patients 70 years and older with a protrusio type acetabulum fracture. DESIGN:: Retrospective case series. SETTING:: Two level 1 trauma centers. PATIENTS:: Between 11/2000 and 12/2009, 39 consecutive patients older than 70 with protrusio acetabulum fractures were enrolled. INTERVENTION:: Open reduction ...
Moriya Mitsutoshi - - 2012
Bipolar hemiarthroplasty (BHA) for idiopathic osteonecrosis of the femoral head (ONFH) is performed at our institution. The purpose of this study was to evaluate the clinical and radiographic findings after BHA for the treatment of steroid -induced ONFH. Thirty-seven hips in 27 patients were assessed (seven men, 11 hips; 20 ...
Choi Seong Jun SJ Department of Otorhinolaryngology, Konyang University, Daejeon, Republic of - - 2012
To identify clinical features and causes of recurrent or persistent benign paroxysmal positional vertigo (BPPV) and to analyze the effectiveness of frequently repeated canalith repositioning procedures (CRPs). Case series with chart review. Academic university hospital. The authors retrospectively reviewed the clinical records of 120 patients who were diagnosed with BPPV ...
Kalil Andre C AC Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198-5400, USA. - - 2012
Drotrecogin alfa (activated) was approved for use in severe sepsis in 2001 on the basis of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis (PROWESS) trial, but controversies about its effectiveness remain. We aimed to assess effectiveness and safety of use of this drug in the past ...
Touma Z - - 2012
Objectives: To determine the frequency and the time to complete recovery identified by Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) and the time to partial recovery identified by the SLEDAI-2K Responder Index 50 (SRI-50) in three laboratory systems over 10 years. Methods: This is a retrospective analysis of the ...
D'Acunto C - - 2012
Over the last years, many different techniques have been utilized to treat age related wrinkles. We describe here two patients with a new type of filler adverse reaction, xanthelasma-like, that appeared after the infiltration of hyaluronic acid in the superficial dermis of the lower eyelids. Case 1 A 49-year-old caucasian ...
Tan P X - - 2012
AIM: Limb-salvage surgery has become the standard of care for extremity osteosarcoma. In this study, we investigated the survival and functional outcomes of patients with osteosarcoma around the knee who were treated with limb-salvage surgery. METHODS: We retrospectively reviewed the clinical data for 120 patients with osteosarcoma around the knee ...
Diab Aliaa A - - 2012
Objective:To investigate the effectiveness of forward head correction on three-dimensional posture parameters and functional level in adolescent idiopathic scoliotic patients.Design:A randomized controlled study with three-month follow-up.Setting:University research laboratory.Subjects:Seventy-six adolescent idiopathic scoliotic patients with Cobb angle ranged from 10° to 30° and craniovertebral angle less than 50° were randomly assigned to ...
O'Donnell Turlough M P - - 2012
We compared a cohort of patients undergoing revision of a minimal resection resurfacing unicompartmental knee arthroplasty (UKA) to total knee arthroplasty (TKA) with a cohort of patients undergoing primary TKA. Both cohorts were matched in terms of age, sex, and body mass index. We collected data on preoperative and postoperative ...
Kurelac Ivan - - 2012
The aim of this study was to analyze the predictive value of CXCL9, CXCL10, and CXCL11 concentrations before and after 4 and 12 weeks of treatment with pegylated interferon-α2b and ribavirin in patients with chronic hepatitis C infected with the hepatitis C virus genotype 1. The study included 46 adult ...
Kallel S S Department of Anesthesiology and Intensive Care, Academic Medical Center Habib Bourguiba, Sfax, Tunisia. - - 2012
Determine the thresholds of procalcitonin (PCT) and N-terminal pro-B-type natriuretic peptide (Nt-pro-BNP) associated with poor prognosis after heart surgery with CPB. Prospective observational study. Academic Medical Center Habib Bourguiba. Adult patients consecutively operated for coronary or valve surgery with CPB, elective or semi-urgent. Serum concentrations of PCT and Nt-pro-BNP were ...
Shlobin Oksana A - - 2012
BACKGROUND: Sildenafil was the only phosphodiesterase-5 inhibitor available for the treatment of pulmonary arterial hypertension (PAH) until the approval and availability of once-daily tadalafil. Since no direct comparative study is likely to be performed between these agents, we sought to evaluate the feasibility of transitioning stable PAH patients from sildenafil ...
Genovese Mark C - - 2012
To evaluate abatacept safety and efficacy over 5 years in patients with rheumatoid arthritis (RA) who had inadequate response to anti-tumor necrosis factor (TNF) therapy in the ATTAIN trial. Patients completing the 6-month, double-blind (DB) placebo-controlled period were eligible to enter the longterm extension (LTE), where all patients received abatacept ...
Yang Rachel L - - 2012
Several treatment options exist for kidney transplant patients with tertiary hyperparathyroidism. However, the decision to endorse observation (OBS), medical therapy, or parathyroidectomy (PTX) remains controversial. We performed a retrospective cohort study of kidney transplant patients with tertiary hyperparathyroidism at a single institution over a 7-year period. Patients were classified by ...
Georgountzou A - - 2012
Aim:  To evaluate the effectiveness, safety and tolerability of propranolol as single agent treatment in patients with problematic, proliferative phase, infantile hemangiomas (IHs). Methods:  Oral propranolol was administered at a dose of 2 mg/kg/day to twenty eight children. Cardiologic evaluation was performed before treatment initiation. Hemodynamic variables and blood glucose ...
Park Do Joon - - 2012
The best treatment option for recurrent papillary thyroid carcinoma (PTC) is reoperation when the recurrent lesion is locoregional. The prognostic significance of serum Tg levels before reoperation and the association between the outcome of reoperation and Tg level remain unclear. Our study aimed to determine the outcomes of patients who ...
Barnes Geoffrey D - - 2012
Total knee arthroplasty (TKA) and total hip arthroplasty (THA) are associated with high rates of venous thromboembolism (VTE). Anticoagulants, such as warfarin, are commonly used to prevent VTE in such patients. The practice and effectiveness of warfarin in real world populations is not well documented. 595 TKA and THA patients ...
Zuraw Bruce L - - 2012
OBJECTIVE: Nanofiltered C1-inhibitor (C1INH-nf) is approved for prophylactic treatment of hereditary angioedema. This study assessed the efficacy and safety of C1INH-nf as prophylactic therapy in a large cohort of patients with hereditary angioedema. METHODS: An open-label multicenter extension study was performed involving 146 subjects with hereditary angioedema who were treated ...
Martins Gerez Fernandes - - 2012
BACKGROUND: Organic inflammatory response is a pathophysiological mechanism present at every coronary artery bypass grafting with extracorporeal circulation (CABG-ECC), the release of inflammatory mediators being one of its defense mechanisms. OBJECTIVE: To assess, in a prospective double-blind randomized and placebo-controlled study, the effects of trimetazidine (Tmz) on the inflammatory response, ...
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