Search Results
Results 451 - 500 of 4684
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Elshoff Lydia - - 2012
Purpose:  In the presurgical evaluation of children and juvenile patients with refractory focal epilepsy, the main challenge is to localize the point of seizure onset as precisely as possible. We compared results of the conventional electroencephalography-functional magnetic resonance imaging (EEG-fMRI) analysis with those obtained with a newly developed method using ...
Fragomen Austin T - - 2012
Ankle arthrodesis may be achieved using the Ilizarov method. Comorbidities, such as diabetes, Charcot neuroarthropathy, osteomyelitis, leg length discrepancy, and smoking, can make an ankle fusion complex and may be associated with lower rates of healing. We asked if (1) smoking and other comorbidities led to lower fusion rates, (2) ...
Ionescu-Ittu Raluca - - 2012
Controversy continues concerning the choice of rhythm control vs rate control treatment strategies for atrial fibrillation (AF). A recent clinical trial showed no difference in 5-year mortality between the 2 treatments. We aimed to determine whether the 2 strategies have similar effectiveness when applied to a general population of patients ...
Peukert Nadine - - 2012
Background: Fractionated photothermolysis (FP) is used for the treatment of facial wrinkles. Objectives: Investigation of effects of different FP treatment parameters in the treatment of facial wrinkles. Patients and methods: In a randomized split-face controlled study 11 patients received 3 FP sessions in 4-week intervals. Keeping the total energy input ...
Said Samir M - - 2012
BACKGROUND: Dronedarone is a new antiarrhythmic agent that has only recently been approved for the therapy of atrial fibrillation (AF). Results regarding a broader spectrum of patients and experience accumulated in clinical practice are still very scarce. Therefore, we prospectively investigated the efficacy and tolerance of dronedarone in a real ...
Dos Santos Juliana Magalhães Reis - - 2012
OBJECTIVE:: To describe the results of endoscopic secondary prophylaxis, alone or in combination with propranolol, used to prevent upper gastrointestinal bleeding (UGIB) in children and adolescents with esophageal varices. METHODS:: This observational study followed 43 patients under 18 years of age who received secondary prophylaxis between August 2001 and December ...
Baker Richard P - - 2012
We identified 45 knees in 42 patients who had an isolated tibial insert exchange for a failed primary knee arthroplasty with a minimum of 2 years of follow-up. The mean age at revision was 68 years, and the mean time to revision was 80 months. Thirty patients completed follow-up questionnaires ...
Artz Neil N Musculoskeletal Research Unit, University of Bristol, Bristol, UK. - - 2013
Total hip replacement (THR) and total knee replacement (TKR) are two common elective orthopaedic procedures, and the provision of physiotherapy for patients after discharge is variable, with evidence for best practice remaining uncertain. To determine the standard physiotherapy service offered to patients following discharge after THR and TKR. A telephone ...
Zibetti Maurizio - - 2012
Duodenal infusion of levodopa/carbidopa gel (Duodopa) is an effective treatment option for advanced Parkinson's disease (PD). Long-term clinical experience up to 16 years suggests that the safety of this procedure is acceptable, while several observational studies showed that Duodopa reduces motor fluctuations and dyskinesias improving patients' quality of life (QoL). The ...
Urso Emanuele D L - - 2012
BACKGROUND: Currently, no guidelines exist for the treatment of patients with multiple colorectal adenomas (MCRAs) (>10 but <100 synchronous nondiminutive polyps of the large bowel). This retrospective study aimed to investigate the clinical and molecular factors related to different treatments for MCRAs. METHODS: Patients with MCRAs were consecutively enrolled from ...
Williamson J Blair - - 2012
Spiral enteroscopy can be safe and effective in the short term for evaluation of obscure GI bleeding, but long-term data are lacking. To assess the long-term clinical outcomes after deep small-bowel spiral enteroscopy performed for obscure GI bleeding. Prospective cohort study. Academic referral center. This study included 78 patients who ...
Kawashiri Shin-Ya - - 2012
We introduced abatacept (ABT) in a very early rheumatoid arthritis (RA) patient with active tenosynovitis of hands defined by musculoskeletal ultrasonography (MSKUS). MSKUS-proven tenosynovitis remarkably improved at 2 months in spite of clinical exacerbation, followed by clinical remission at 5 months. MSKUS abnormalities also disappeared. Although ABT was discontinued due to an ...
Sabatowski Rainer - - 2012
Abstract Objective: Prospective evaluation of the long-term efficacy and safety of the 5% lidocaine medicated plaster in patients with post-herpetic neuralgia (PHN). Research design and methods: Patients with persisting pain for ≥ 3 months after acute herpes zoster and a baseline pain intensity of at least 4 on an 11- ...
Zarraga Ignatius Gerardo E - - 2012
BACKGROUND: -Previous studies have suggested that aldosterone blockade can reduce the incidence of ventricular tachycardia (VT) or ventricular fibrillation (VF) in patients with heart failure (HF). The SPIronolactone to Reduce ICD Therapy (SPIRIT) trial was designed to test the hypothesis that spironolactone reduces the incidence of VT/VF in patients with ...
Rolf Sascha - - 2012
BACKGROUND: -We describe a novel fluoroscopy co-registered 4D catheter tracking technology (MGT) used for treatment of patients with atrial fibrillation (AF). The aim of the study was to investigate (i) feasibility of non-fluoroscopic catheter manipulation within dynamic left atrial chamber models, (ii) integration of the technology into an established electroanatomical ...
Kim Hee Jin - - 2012
Background: Delayed facial palsy (DFP) after microvascular decompression (MVD) in patients with hemifacial spasm (HFS) is not uncommon, but the cause remains unknown. Objectives: To assess whether intraoperative electromyography (EMG) and brainstem auditory evoked potential (BAEP) can predict DFP after MVD. Methods: Between September 2009 and February 2011 we examined ...
Sen Keiiku - - 2012
Aim:  We have examined the risk factors and management processes of the persistent occiput posterior (pOP) position by analyzing medical records from our hospital. Material and Methods:  Medical records and delivery notes from January 2007 to December 2009 were reviewed and 103 patients were identified as having the pOP position ...
Bakker-Dyos Josh - - 2012
We evaluated the use of a cemented constrained acetabular component to treat recurrent or potential instability after hip replacement. Over a seven year period, 109 patients who had undergone 110 operations were identified from hospital records. Patients were reviewed based on clinical and radiological follow-up. Post-operative function and quality of ...
Thompson Eric M - - 2012
Object Vagus nerve stimulation (VNS) is approved by the FDA for the treatment of partial epilepsy in patients older than 12 years. Authors of the current study performed a large retrospective analysis and comparison of VNS outcomes in children with an age ≥ and < 12 years, including those with ...
McGowan Meghan L - - 2012
Objective To analyze the association between concentration, as measured by the Interactive Metronome, and a prolonged second stage of labor in nulliparous patients.Study Design From September 2008 to November 2009, nulliparous women at ≥34 weeks' gestation who were planning to use an epidural were asked to perform a 1-minute Interactive ...
Delgado Acosta F - - 2012
OBJECTIVES: To evaluate the recanalization rate and clinical outcome three months after endovascular treatment for vertebrobasilar occlusion before the placement of stentrievers. MATERIAL AND METHODS: We reviewed all cases of basilar thrombosis treated with endovascular techniques at our center. We reviewed the clinical outcomes with the main objective of determining ...
van Dussen Laura - - 2012
This paper describes the effects of a switch to velaglucerase alfa in a group of adult patients with type 1 Gaucher disease all of whom had previously had their dose reduced as a consequence of the worldwide imiglucerase shortage.Thirty-two patients from two large European Gaucher centers switched to treatment with ...
Lim Alan A - - 2012
ABSTRACT: Patients with congenital craniofacial malformations present with complex challenges for reconstruction. Successful management requires individualized treatment often involving rebuilding the facial skeleton de novo, as well as correcting the overlying soft-tissue deficiencies in the final stages. At the University of California, Los Angeles (UCLA) Craniofacial Clinic, serial autologous fat ...
Harwin Steven F - - 2012
Total knee arthroplasty can be challenging in Jehovah's Witnesses, as these patients do not accept blood transfusions. We reported our experiences with a special blood management protocol for these patients who underwent total knee arthroplasty. There were 124 self-reported Jehovah's Witnesses who had a mean age of 64 years and ...
Erkapic Damir - - 2012
AimsPrevention of sudden cardiac death by means of the implantable cardioverter/defibrillator (ICD) is considered to be a lifelong therapy. However, it is still unresolved if patients who never experienced an appropriate ICD intervention during generator longevity really need to undergo device replacement.Methods and resultsThe INSURE trial was a multicentre prospective ...
Meno H - - 2012
Many patients with hypertension have difficulty achieving their target blood pressure (BP). Therefore combination therapy, for example with an angiotensin II receptor blocker (ARB) and a diuretic, may be recommended. We previously evaluated the efficacy and safety of losartan (LOS) 50 mg - hydrochlorothiazide (HCTZ) 12.5 mg, as well as ...
Kapoor Akshay - - 2012
OBJECTIVES: To evaluate the markers of lymphocyte activation (sIL-2R, IL-6 and TNF α) in the peripheral blood of newly diagnosed patients with celiac disease (CD) and patients with CD on Gluten free diet (GFD) for at least 2 y. The markers were correlated with conventional serological tests Anti-tissue transglutaminase (Anti-TTG) used ...
Rochlin Danielle H - - 2012
BACKGROUND: Surgical treatment for neurogenic thoracic outlet syndrome does not always yield successful outcomes. The purpose of this study was to describe patients with unresolved, recurrent, and/or contralateral symptoms following first rib resection and scalenectomy (FRRS) and to determine therapies for improving their outcomes. METHODS: Data on 161 neurogenic thoracic ...
Ozkan Ugur - - 2012
PURPOSE: We aimed to assess the degree of improvement in chronic venous disease-related symptoms after endovenous laser ablation (EVLA) for saphenous vein insufficiency. MATERIALS AND METHODS: The study was conducted as a single-center, single-arm prospective cohort study. The series was comprised of 55 limbs of 38 patients (24 [63%] females, ...
Lennert Barb - - 2012
Seizures are a hallmark manifestation of tuberous sclerosis complex, yet data characterizing resource utilization are lacking. This retrospective chart review was performed to assess the economic burden of tuberous sclerosis complex with neurologic manifestations. Demographic and resource utilization data were collected for 95 patients for up to 5 years after ...
Mikolajczak S - - 2012
Cidofovir is an antiviral agent used in the therapy of recurrent respiratory papillomatosis (RRP). In this study, we hypothesized that cidofovir is effective in decreasing the viral load of human papillomavirus (HPV). We established a type specific real-time PCR and measured HPV DNA loads. The course of viral load of ...
Boyd Scott B SB Department of Oral and Maxillofacial Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232-2103, USA. - - 2013
To present a new measurement instrument, the Effectiveness of Treatment Apnea-Hypopnea Index (ET-AHI), which the authors developed to determine an estimate of the therapeutic control of obstructive sleep apnea (OSA). The authors retrospectively evaluated a cohort of patients with OSA who initially attempted to use continuous positive airway pressure (CPAP) ...
Mbuba Caroline K CK KEMRI/Wellcome Trust Research Programme, Centre for Geographic Medicine Research (Coast), Kilifi, - - 2012
Many people with epilepsy in low-income countries do not receive appropriate biomedical treatment. This epilepsy treatment gap might be caused by patients not seeking biomedical treatment or not adhering to prescribed antiepileptic drugs (AEDs). We measured the prevalence of and investigated risk factors for the epilepsy treatment gap in rural ...
Morschhauser F - - 2012
BackgroundThis study explored the efficacy and safety of rituximab as treatment of clinical or molecular residual disease after autologous stem-cell transplantation (ASCT) in follicular lymphoma (FL).Patients and methodsForty patients with CD20+ FL and clinically (group A, n = 14) or clono-specific PCR-detectable (group B, n = 25) residual disease persisting 3 months after ASCT ...
Bachour Adel - - 2012
PURPOSE: This study aimed to evaluate the care receiver's satisfaction with the continuous positive airway pressure (CPAP) interfaces. METHODS: A questionnaire with visual analog scales was sent to all our CPAP patients (0 = absolutely unsatisfied, 100 = very satisfied). From the ResMed ResScan program, we obtained the CPAP daily use and air leak ...
Desie Nele - - 2012
OBJECTIVE: The aim of this study was to determine whether intra-abdominal pressure (IAP) monitoring using the FoleyManometer (Holtech Medical, Charlottenlund, Denmark) increases the risk of urinary tract infection (UTI). DESIGN: A retrospective database review was conducted. SETTING: The study was conducted in the 12-bed medical intensive care unit of ZNA ...
Rehnitz Christoph - - 2012
The purpose of this study was to retrospectively evaluate long-term success of CT-guided radiofrequency ablation (RFA) in patients with osteoid osteoma (OO) and osteoblastoma (OB) including tumors in critical locations. Eighty-one CT-guided RFA procedures were performed in 77 patients with OO (65 patients) and OB (12) including 6 spinal and ...
Gil-Nagel Antonio - - 2012
Interim results of two open-label extension studies assessed ezogabine/retigabine safety and tolerability for partial-onset seizures. At data cutoff, 336 (60%) patients received ≥ 12 months' open-label ezogabine/retigabine. The most common TEAEs included dizziness (22%), somnolence (19%), headache (14%), and fatigue (10%). Change in seizure frequency from baseline (median reduction, 53%) ...
Cordemans Colin - - 2012
Achievement of a negative fluid balance in patients with capillary leak is associated with improved outcome. We investigated the effects of a multi-modal restrictive fluid strategy aiming for negative fluid balance in patients with acute lung injury (ALI). In this retrospective matched case-control study, we included 114 mechanically ventilated (MV) ...
Hetts S W - - 2012
BACKGROUND AND PURPOSE:NGAVFs are rare vascular malformations usually presenting in infancy or childhood. We sought to identify clinical and angiographic predictors of clinical outcome for these lesions.MATERIALS AND METHODS:Retrospective review of a neurointerventional data base identified 386 pediatric patients with intracranial AVFs and AVMs, from which a cohort of 25 ...
Pekkola J - - 2012
BACKGROUND AND PURPOSE:Peripheral AVM is a locally aggressive disease with a high tendency to recur; its treatment is complex, especially in the anatomically delicate head and neck area. Here, we report results of ethanol sclerotherapy for head and neck AVM and discuss its potential use for peripheral AVM.MATERIALS AND METHODS:We ...
Haill C F - - 2012
BACKGROUND: Outbreaks of norovirus can have a significant operational and financial impact on healthcare establishments. AIM: To assess whether containment of symptomatic patients in single rooms and bays at the beginning and end of norovirus outbreaks reduced the length of bed closure. METHODS: In 2007, we introduced a new strategy ...
Gulati Ashima - - 2012
There are limited data on the relative efficacy and safety of calcineurin inhibitors and alkylating agents for idiopathic steroid-resistant nephrotic syndrome in children. To clarify this, we compared tacrolimus and intravenous cyclophosphamide therapy in a multicenter, randomized, controlled trial of 131 consecutive pediatric patients with minimal change disease, focal segmental ...
Nakagawa Takayuki - - 2012
OBJECTIVE: To examine the effects of topically applied recombinant human insulin-like growth factor 1 (IGF1) via gelatin hydrogels on alterations in pure-tone audiometry (PTA) in patients with sudden sensorineural hearing loss (SSHL) refractory to systemic steroids. STUDY DESIGN: Retrospective chart review. SETTING: A single university hospital. PATIENTS: Twenty-five patients with ...
Nizič Tea - - 2012
AIM OF THE STUDY: To compare clinical effectiveness and safety of treatment with clarithromycin and amoxicillin in children with solitary erythema migrans (EM). METHODS: Consecutive patients younger than 15 years, referred to our institution in 2004 and 2005 with previously untreated solitary erythema migrans, were included in this prospective study. ...
Reibetanz Joachim - - 2012
PURPOSE: The objective of the present study was to compare the postoperative outcomes between obese and normal-weight patients undergoing single-port cholecystectomy (SPC) for gallstone disease. METHODS: A prospectively maintained SPC-database was retrospectively analyzed, and the outcomes of obese [body mass index (BMI) ≥30 kg/m(2)] and normal-weight patients were compared. All patients ...
Bänsch Dietmar - - 2012
AIMS: Circumferential pulmonary vein isolation (PVI) is the current standard of interventional atrial fibrillation (Afib) therapy. However, recurrence rate of Afib varies considerably after ablation between different series and is mainly attributed to the recovery of pulmonary vein (PV) conduction after initial successful PVI.STUDY HYPOTHESIS: Waiting longer during the initial ...
Cunningham Gregory - - 2012
Background:  Motorcyclists have the highest morbidity and mortality rates of all road users. Little evidence is available to demonstrate how rider, crash and speed influence short- and long-term patient outcomes. Methods:  A prospective study of 208 consecutive crash presentations was undertaken at the Royal Perth Hospital, Western Australia. All motorcycle, ...
Rueth Natasha M - - 2012
BACKGROUND: Esophageal stents provide immediate palliation of malignant dysphagia; however, radiotherapy (RT) is a superior long-term option. We review the outcomes of combined esophageal stenting and RT for patients with malignant dysphagia. METHODS: We retrospectively reviewed patients with esophageal stents placed for palliation of malignant dysphagia from esophageal stricture, esophageal ...
Kim Tae Beom - - 2012
Study Type - Prognosis (cohort) Level of Evidence 2b What's known on the subject? and What does the study add? The second to fourth digit ratio (hereafter the digit ratio) of the right hand is related to the activity of the androgen receptor. Five α-reductase inhibitor (5ARI) reduces the prostate volume ...
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