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Vagheggini Guido G Pulmonary Rehabilitation, and Weaning Unit, Auxilium Vitae, - - 2014
The need for prolonged mechanical ventilation (PMV) after cardiac surgery is still a common problem. We hypothesized that subjects who required PMV after a single surgery (either coronary artery bypass grafting or valve surgery) would have better outcomes than those who had experienced both revascularization and valve surgery. We retrospectively ...
Fassl J J Department of Anaesthesia, Surgical Intensive Care, Prehospital Emergency Medicine and Pain Therapy, University Hospital Basel, CH-4031 Basel, - - 2014
Although infusion of fibrinogen concentrate is increasingly used in bleeding patients after cardiac surgery, safety data are scarce. We aimed to evaluate the effect of perioperative administration of fibrinogen concentrate on postoperative morbidity and mortality in patients undergoing cardiac surgery. During a 2 yr study period, 991 patients underwent cardiac ...
Sharma Rajni - - 2014
Background: Endocrinopathies are common in patients with thalassaemia major (TM) despite parenteral iron chelation therapy with deferoxamine. There are only a few studies on the efficacy of oral deferiprone in preventing endocrine dysfunction. Aim: To determine the growth and endocrine complications in children with TM receiving oral iron chelation with ...
Weigand Justin J Division of Pediatric Cardiology, New York-Presbyterian Morgan Stanley Children's Hospital/Columbia University Medical Center, 3959 Broadway, 2 North, New York, NY, 10032-3784, USA, - - 2014
Little is known about preoperative factors affecting postoperative morbidity following anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) repair. This study aimed at identifying predictors of postoperative outcomes, including mortality and left ventricle (LV) normalization. A retrospective, single institution review was conducted on forty-four ALCAPA repairs ...
Hatipoglu Esra E Division of Endocrinology and Metabolism, Department of Internal Medicine, Cerrahpasa Medical School, University of Istanbul, Istanbul, - - 2014
We aimed to evaluate the disease activity of medically controlled patients with acromegaly after withdrawal of somatostatin receptor ligands (SRL). Sixteen patients who were on a stable dose of SRL for more than 2 years and had at least 1 year of remission were included in the study. Five patients were on ...
Kara Orhan Deniz OD Denizli State Hospital , Denizli , Turkey - - 2014
Abstract Introduction: As intensive care units (ICU) have improved, presence of multiple-organ dysfunctions in majority of patients with acute renal failure (ARF) has become clearer. To facilitate multi-organ support, continuous renal replacement therapy (CRRT) techniques have been developed. This study is the one that reports the experience on children including ...
Corkal James C JC Department of Clinical Neurological Sciences, London Health Sciences Centre, University Hospital, Rm. C7-131, 339 Windermere Road, London, ON, N6A 5A5, - - 2014
Healthy subjects with asymptomatic postural tachycardia (≥30 bpm) at baseline were evaluated over a 1-year period to determine whether they developed orthostatic symptoms. Subjects were evaluated at baseline and at 1 year using the autonomic reflex screen and autonomic symptom profile (ASP). Heart rate increment on HUT did not differ at baseline ...
Nunes V S VS Department of Internal Medicine, Botucatu Medical School, Sao Paulo State University/UNESP, Sao Paulo, Brazil, - - 2014
Whether the preoperative use of somatostatin analogues (SA) improves surgical outcomes in acromegaly is still a matter of debate. We conducted a systematic review of randomized, controlled trials that compared the short-term outcomes of preoperative use of SA (Pre-SA) with direct TSS (No-SA) for the treatment of newly diagnosed acromegaly. ...
Tian Mao-Lu ML Institute of Nephritic and Urinary Disease, Guizhou Provincial People's Hospital, Guiyang - - 2014
Urinary alkalinization with sodium bicarbonate infusion can theoretically protect against the mechanisms of acute kidney injury. Controversy exists regarding whether sodium bicarbonate infusion can reduce the incidence of acute kidney injury from cardiac surgery. A meta-analysis was conducted to show the efficacy and safety of perioperative sodium bicarbonate use for ...
Stammet Pascal P Department of Anaesthesia and Intensive Care Medicine, Centre Hospitalier de Luxembourg, 4, rue Barblé, L-1210 Luxembourg. Electronic address: - - 2014
To address the value of continuous monitoring of bispectral index (BIS) to predict neurological outcome after cardiac arrest. In this prospective observational study in adult comatose patients treated by therapeutic hypothermia after cardiac arrest we measured bispectral index (BIS) during the first 24hours of intensive care unit stay. A blinded ...
Xiao Cangsong C Department of Cardiovascular Surgery, the People's Liberation Army General Hospital, Beijing, - - 2014
Robotic technology has been applied to atrial septal defect (ASD) repair for more than 10 years, but the number of cases reported is limited and results of long-term follow-up are not clear. This study reports on a large group of patients who underwent totally robotic ASD repair on an arrested ...
Mercado Moises M Endocrinology Service/Experimental Endocrinology - - 2014
Context: Acromegaly is usually due to the excessive secretion of GH by a pituitary adenoma. It is frequently accompanied by co-morbidities which compromise quality of life and results in elevated mortality rates. Objective: To evaluate mortality and morbidity in patients with acromegaly receiving multimodal care. Setting: Tertiary care center. Design, ...
Kumar Sanjay S SUNY Downstate Medical Center, Brooklyn, NY, USA; Marshfield clinic-weston center, Weston, WI, - - 2014
Takotsubo cardiomyopathy (TTC) is a condition of reversible left ventricular (LV) systolic dysfunction. However, the diastolic function (DF) manifestations of TTC have not been widely investigated. We performed a bicentric study with retrospective analysis of DF in patients with TTC, during onset and at follow-up. Twenty-eight patients with TTC (64 ± 10 years, ...
McNeilly R G RG Department of Anaesthesia, Royal Victoria Hospital, 274 Grosvenor Road, Belfast BT12 6BA, UK. Electronic address: - - 2014
An understanding of heart-circulation interaction is crucial to our ability to guide our patients through an episode of septic shock. Our knowledge has advanced greatly in the last one hundred years. There are, however, certain empirical phenomena that may lead us to question the wisdom of our prevailing treatment algorithm. ...
Camuglia Anthony C AC Mater Health Cardiovascular Unit, South Brisbane, Queensland, Australia; Princess Alexandra Hospital, Department of Cardiology, Queensland, Australia; University of Queensland, Queensland, Australia. Electronic address: - - 2014
Survivors of out-of-hospital cardiac arrest (OHCA) have a high rate of morbidity and mortality. Invasive cardiac assessment with coronary angiography offers the potential for improving outcomes by facilitating early revascularization. The aim of the present study was to review the published data on early coronary angiography for survivors of OHCA, ...
Han Jenny E - - 2014
Simulation training is widely accepted as an effective teaching tool, especially for dealing with high-risk situations. We assessed whether standardized, simulation-based advanced cardiac life support (ACLS) training improved performance in managing simulated and actual cardiac arrests. A total of 103 second- and third-year internal medicine residents were randomized to 2 ...
Kim Do Young do Y Department of Neurosurgery, Gangnam Severance Hospital, Yonsei University College of Medicine Seoul, - - 2014
The clinico-radiologic features of the spontaneous basal ganglia hemorrhage (BGH) may often differ one from another, according to its regional location. Therefore, we attempted to classify the BGH into regional subgroups, and to extrapolate the distinct characteristics of each group of BGH. A total of 103 BGHs were analyzed by ...
Hudson Jordan K C JK Department of Anesthesiology, University of Ottawa, Ottawa, Ontario, Canada. Electronic address: - - 2014
Continuous aspiration of subglottic secretions (CASS) has been found to decrease the incidence of pneumonia in the general intensive care unit (ICU) population, but its benefit in cardiac surgery patients is unclear. The present study aimed to determine whether the routine use of CASS in cardiac surgical patients was associated ...
Fürnkranz Alexander A Cardioangiologisches Centrum Bethanien, Wilhelm Epstein Strasse 4, 60431, Frankfurt aM, - - 2014
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia imposing substantial morbidity and mortality. Catheter-based pulmonary vein isolation (PVI) using radiofrequency current (RFC) has become a standard treatment for drug-resistant and symptomatic paroxysmal AF (PAF). In recent years, the cryoballoon-based technique is increasingly used as a promising alternative with ...
Sepehri Aresh A Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, - - 2014
Current preoperative assessments for cardiac surgery, such as the European System for Cardiac Operative Risk Evaluation II and the Society of Thoracic Surgeons risk score, are limited in their ability to predict postoperative outcomes. This is thought to be due to the reliance on chronological age as a predictor of ...
Badhwar Vinay V Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pa. Electronic address: - - 2014
Prolonged intubation has been implicated in the poor outcomes after adult cardiac surgery. Accelerated postoperative extubation has been a quality focus, but operating room (OR) extubation after cardiopulmonary bypass is rare. We examined the outcomes and direct costs of protocolized OR extubation versus early postoperative intensive care unit (ICU) extubation ...
Press Y K YK Integrated Statistics, 16 Sumner Street, Woods Hole, MA, 02543, - - 2014
Winter flounder Pseudopleuronectes americanus were collected at monthly intervals from December 2009 to May 2011, to describe the pattern and seasonality of oocyte development, including: (1) the group-synchronous transition from primary to secondary oocytes that initiates immediately after spawning, (2) the slow (months) development of vitellogenic oocytes followed by the ...
Panchanathan Karthik K Department of Anthropology,University of Missouri,Columbia,MO - - 2014
Smaldino is right to argue that we need a richer theory of group-level traits. He is wrong, however, in limiting group-level traits to units of cultural selection, which require explanations based on group selection. Traits are best understood when explanations focus on both process (i.e., selection) and product (i.e., adaptation). ...
Caporael Linnda R LR Department of Science and Technology Studies,Rensselaer Polytechnic Institute,Troy, NY - - 2014
Although both a "simple dyad or a population of thousands" are groups, these are, respectively, face-to-face embodied groups and collective symbolic groups. We applaud Smaldino for recognizing and describing the concept of the group-level trait. As an expansion, we propose an evolutionary-developmental model of face-to-face groups that scaffolds theorizing the ...
Gordon Pedro Caldana PC Department of Psychiatry, Faculty of Medicine, University of São Paulo, São Paulo, Brazil, - - 2014
A significant proportion of patients who undergo bariatric surgery fail to achieve enduring weight loss. Previous studies suggest that psychosocial variables affect postoperative outcome, although this subject is still considered unclear. The purpose of this study is to further investigate the impact of psychosocial variables on Roux-en-Y gastric bypass (RYGB) ...
Mandy Anne A Reader, Director of Post Graduate Studies, Centre for Health Research, University of Brighton, Eastbourne, Sussex, United Kingdom. Electronic address: - - 2014
Limited published data exploring patients' emotional recovery after day case foot surgery are available. The aim of the present study was to explore the changes in patient mood from preoperatively to 8 weeks postoperatively after outpatient forefoot surgery. The patients completed the Profile of Mood States-Bipolar™ questionnaire, Speilberger State-Trait Anxiety ...
Tosun Betül B Department of Fundamentals of Nursing, School of Nursing, Gulhane Military Medical Academy, Ankara, - - 2014
The aim of the study was to evaluate the effects of preoperative fasting and fluid limitation in patients undergoing laparoscopic cholecystectomy. Although traditional long-term fasting is not recommended in current preoperative guidelines, this is still a common intervention. Visual analogue scale was used to assess hunger, thirst, sleepiness, exhaustion, nausea ...
Fanelli A A Department of Anesthesia and Pain Therapy, Istituti Ospitalieri di Cremona, Cremona, Italy - - - 2014
Background: This study aims at investigating the effect of a single pre-operative oral administration of morphine sulphate (Oramorph®) on pain after laparoscopic cholecystectomy (LC). Methods: Forty-one ASA I-III patients, aged 18-65 years, undergoing LC were randomly, double-blindly allocated to treatment (N.=20, 30mg Oramorph®, group M) or placebo (N.=21, group P). ...
Vance Jennifer L JL Department of Anesthesiology, University of Michigan Medical School, 1H247 UH Box 5048, 1500 East Medical Center Drive, Ann Arbor, MI 48109, - - 2014
Fast track recovery is a care process goal after cardiac surgery. Intraoperative anesthetic depth may impact recovery, but the impact of brain monitoring on time to extubation and intensive care unit (ICU) length of stay after cardiac surgery has not been extensively studied. Our goal was to determine if BIS-guided ...
Kotila T R - - 2013
The high prevalence of sickle cell disorders and the mild deletional alpha-thalassaemia among Nigerians is well known, but beta-thalassaemia is believed to be almost nonexistent. Beta thalassaemia trait (BTT) was screened for in patients with unexplained recurrent haemolytic anaemia and healthy individuals. beta-thalassaemia trait (BTT) was screened for using MCH ...
Kotila T R TR Department of Haematology, College of Medicine, University of Ibadan, Ibadan, Nigeria. - - 2013
The high prevalence of sickle cell disorders and the mild deletional á-thalassaemia among Nigerians is well known, but â-thalassaemia is believed to be almost nonexistent. Beta thalassaemia trait (BTT) was screened for in patients with unexplained recurrent haemolytic anaemia and healthy individuals. â-thalassaemia trait (BTT) was screened for using MCH ...
Fanelli A - - 2013
Background: This study aims at investigating the effect of a single pre-operative oral administration of morphine sulphate (Oramorph®) on pain after laparoscopic cholecystectomy (LC). Methods: 41 ASA I-III patients, aged 18-65 years, undergoing LC were randomly, double-blindly allocated to treatment (n=20, 30mg Oramorph®, group M) or placebo (n=21, group P). ...
Blumenthal Claire - - 2013
Object It is not known whether adding fusion to lumbar decompression is necessary for all patients undergoing surgery for degenerative lumbar spondylolisthesis with symptomatic stenosis. Determining specific radiographic traits that might predict delayed instability following decompression surgery might guide clinical decision making regarding the utility of up-front fusion in patients ...
Costa Cyrene Piazera Silva - - 2013
The purpose of this study was to evaluate the association between sickle cell anemia (SCA) and pulp necrosis (PN). One hundred thirteen individuals with SCA (ie, the exposed group) from the Supervision of Hematology and Hemotherapy of Maranhão (HEMOMAR), Maranhão, Brazil, and 226 individuals without SCA, the sickle cell trait, ...
Tutuncu Yasemin - - 2012
Long-acting somatostatin analogs are frequently used as adjuvant treatment of acromegaly patients after noncurative surgery. This sudy aims to compare the efficacy of octreotide long-acting release (OCT) and lanreotide Autogel (LAN) in acromegaly patients. Sixty-eight patients not cured by transsphenoidal endoscopic or microscopic pituitary surgery between 2003 and 2009 were ...
Kapoor Kapil - - 2012
Acute kidney injury (AKI) is a serious complication of malaria which has a very high mortality rate. A retrospective analysis of medical record data of children treated for malarial AKI in a paediatric intensive care unit (PICU) was performed in order to evaluate the incidence, poor prognostic factors and outcome ...
Burns Matthew - - 2012
A double-blind phase III malaria prevention trial was conducted in two refugee camps using pre-manufactured insecticide-treated plastic sheeting (ITPS) or untreated polyethylene sheeting (UPS) randomly deployed to defined sectors of each camp. In Largo camp the ITPS or UPS was attached to inner walls and ceilings of shelters, whereas in ...
Brown Joshua B - - 2012
Controversy surrounds the optimal ratios of blood (packed red blood cell [PRBC]), plasma (fresh frozen plasma [FFP]) and platelet (PLT) use for patients requiring massive transfusion (MT) owing to possible survival bias in previous studies. We sought to characterize mortality during the first 24 hours while controlling for time varying ...
- - 2012
The purpose of this multicenter study is to determine the utility of the erythrocyte sedimentation rate, C-reactive protein, and synovial fluid white blood cell (WBC) count and differential for evaluating periprosthetic joint infection (PJI) in patients with a failed unicompartmental knee arthroplasty (UKA). A total of 259 patients undergoing revision ...
Maiga Amelia W - - 2012
Plasmodium falciparum resistance to artemisinins by delayed parasite clearance is present in Southeast Asia. Scant data on parasite clearance after artemisinins are available from Africa, where transmission is high, burden is greatest, and artemisinin use is being scaled up. Children 1-10 years of age with uncomplicated malaria were treated with ...
Kato Tetsuro - - 2012
Malaria is one of the most common and serious infectious diseases in the tropics and subtropics. For high-risk travelers to endemic regions, malaria chemoprophylaxis is recommended. Internationally, atovaquone-proguanil (A/P), mefloquine (MEF), or doxycycline (DOX) are the prescribed malaria chemoprophylactic drugs. However, A/P and DOX are not approved in Japan. Therefore, ...
Gupte Snehalata C - - 2012
Background & objectives: Literature reports several studies on ABO groups and malaria but a study with an adequate sample size and controls is not available. ABO groups are genetically controlled, hence, large sample size and comparison with population frequency is essential. To determine whether malaria infection with variable severity has ...
Cortez M R - - 2012
The effects of azadirachtin and ecdysone on the Trypanosoma cruzi population in the Rhodnius prolixus gut were investigated. T. cruzi were rarely found in the gut compartments of azadirachtin-treated larvae. High parasite numbers were observed in the stomach of the control and ecdysone groups until 10 days after treatment and ...
Valecha Neena - - 2012
BackgroundArtemisinin based combination therapy (ACT) is the first-line treatment for uncomplicated falciparum malaria. The current study assessed the antimalarial efficacy and safety of a combination of 150 mg of arterolane maleate and 750 mg of piperaquine phosphate in comparison to Coartem(®) (artemether and lumefantrine) in patients with acute uncomplicated P. ...
Jans O - - 2012
Background and Objectives  Bleeding and postoperative anaemia after total hip arthroplasty (THA) may trigger transfusion of red blood cells (RBC). However, large observational studies have reported associations between RBC transfusion and increased postoperative morbidity and mortality. As major bleeding or severe postoperative anaemia is intrinsically linked with RBC transfusion, direct ...
Rueangweerayut Ronnatrai R Department of Internal Medicine, Mae Sot General Hospital, Tak, - - 2012
Pyronaridine-artesunate is an artemisinin-based combination therapy under evaluation for the treatment of Plasmodium falciparum and P. vivax malaria. We conducted a phase 3, open-label, multicenter, noninferiority trial that included 1271 patients between 3 and 60 years of age from Asia (81.3%) or Africa (18.7%) with microscopically confirmed, uncomplicated P. falciparum ...
Tan Josenia N M - - 2012
We implemented a protocol incorporating a higher fresh frozen plasma (FFP)/RBC ratio for the management of trauma patients requiring massive transfusion in 2007. This study aims to identify issues that affected the effective deployment of the massive transfusion protocol (MTP) and compare outcome variables with a historic cohort. Data from ...
Fuller Brian M - - 2012
The exact role of packed red blood cell (PRBC) transfusion in the setting of early resuscitation in septic shock is unknown. To evaluate whether PRBC transfusion is associated with improved central venous oxygen saturation (ScvO(2)) or organ function in patients with severe sepsis and septic shock receiving early goal-directed therapy ...
Sharma Surya K - - 2012
Development of insecticide resistance in malaria vectors has been a major problem for achieving effective vector control. Due to limited availability of insecticides, the only option is management of resistance by judiciously using the insecticides and rotating them to maintain their effectiveness. This study was carried out in a malaria ...
Mayxay Mayfong M Wellcome Trust-Mahosot Hospital-Oxford University Tropical Medicine Research Collaboration, Mahosot Hospital, Vientiane, Laos. - - 2012
We conducted an open-label, randomized clinical trial to assess parasite clearance times (PCT) and the efficacy of 4 mg/kg (group 1, n = 22) and 2 mg/kg (group 2, n = 22) of oral artesunate for three days followed by artemether-lumefantrine in patients with uncomplicated Plasmodium falciparum malaria at Xepon ...
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