Search Results
Results 301 - 350 of 1411
< 2 3 4 5 6 7 8 9 10 11 12 >
Nyman J - - 2009
Twenty (20) CPB-circuits were randomized to a CO(2) group or a control group. In the CO( 2) group, each circuit was flushed with CO(2) (10L/min) at the top of the venous reservoir for 5 minutes, after which priming fluid was added without interruption of the CO(2) inflow. Control group circuits ...
Demir Tolga - - 2009
BACKGROUND: Cerebral injury is a well-known complication after cardiac surgery with cardiopulmonary bypass (CPB), especially in adult patients. Specific biochemical markers like neuron-specific enolase (NSE) and S-100beta protein were developed previously for early detecting neuronal damage after CPB. Corticosteroids are shown to reduce multisystemic deleterious effects of cardiopulmonary bypass due ...
Luciani Remo - - 2009
Cardiac surgery with cardiopulmonary bypass is associated with a systemic inflammatory response syndrome. The major clinical features of this include a reduction of pulmonary compliance and increased extracellular fluids, with increased pulmonary shunt fraction similar to acute respiratory distress syndrome, thus resulting in prolonged mechanical ventilation time (VAM) and intensive ...
Au Brigham K - - 2009
BACKGROUND: Large-volume blood transfusions have been implicated in the development of hyperkalemia. The purpose of the current study was to determine whether critically injured patients receiving massive transfusions are at an increased risk of hyperkalemia. METHODS: Massive transfusion (MT) cohort, all trauma patients (02/2004-01/2008) taken directly to the OR and ...
Garc??a-Erce J A - - 2009
BACKGROUND: Preoperative anaemia is a major risk factor for allogeneic blood transfusion (ABT) in patients undergoing hip fracture repair. We investigated the efficacy of preoperative recombinant human erythropoietin (rHuEPO) administration for reducing ABT requirements in a series of consecutive hip fracture patients presenting with haemoglobin (Hb) between 10 g/dl and ...
Shander Aryeh - - 2009
BACKGROUND: Transfusion rates remain high in cardiac and orthopedic surgery and differ widely across physician practices in spite of growing knowledge that allogeneic blood transfusion (ABT) is associated with a risk of postoperative infection. METHODS: This prospective observational study compared the timing and incidence of ABT-associated postoperative infections (PIs) in ...
Lisbôa Raquel S - - 2009
This study reports the experimental transmission of Borrelia anserina to domestic chickens by infected Argas (Persicargas) miniatus. Clinical alterations as well as prepatent and patent periods were evaluated. Twenty-seven 67-day-old birds were divided into three groups in a randomized experimental design. The first group was exposed to ticks infected with ...
Qi Zhen-xi - - 2009
OBJECTIVE: To probe into the mechanism of Chinese drugs for promoting blood circulation and eliminating blood stasis in the prevention and treatment of glucocorticoid-induced ischemic necrosis of femoral head. METHODS: Thirty New Zealand adult white rabbits were randomly divided into a normal control group (n=5) and a model group (n=25). ...
Surgenor Stephen D - - 2009
BACKGROUND: Exposure to red blood cell (RBC) transfusions has been associated with increased mortality after cardiac surgery. We examined long-term survival for cardiac surgical patients who received one or two RBC units during index hospitalization. METHODS: Nine thousand seventy-nine consecutive patients undergoing coronary artery bypass graft, valve, or coronary artery ...
Dente Christopher J - - 2009
INTRODUCTION: Transfusion practices across the country are changing with aggressive use of plasma (fresh-frozen plasma [FFP]) and platelets during massive transfusion with current military recommendations to use component therapy at a 1:1:1 ratio of packed red blood cells to FFP to platelets. METHODS: A massive transfusion protocol (MTP) was designed ...
Kiliç D - - 2009
OBJECTIVE: The powerful precept of preoperative risk assessment has been applied to compare the efficacy of leukofiltration techniques for high-risk cohorts with the documentation of broad indicators of systemic inflammation. METHODS: Forty high risk patients were prospectively assigned to four perfusion protocols; the first group (n=10): Polyethyleneoxide (PEO) based heparin ...
Hecht-Dolnik Marketa - - 2009
OBJECTIVE: Hetastarch is an artificial colloid widely used intraoperatively in fluid-replacement regimens. Previous studies have found that the intraoperative administration of hetastarch may increase the risk of postoperative bleeding in patients who undergo coronary artery bypass graft surgery with cardiopulmonary bypass. Previous published reports have not examined this risk in ...
Wang Xianqiang - - 2009
OBJECTIVE: Use of aprotinin has been suspended in cardiac surgery since recent studies reported its risks associated with mortality and other adverse events. This study was to investigate the safety and efficacy of aprotinin through a comparison before and after aprotinin was suspended in cardiac surgery. METHODS: We designed a ...
Shahian Mozhgan - - 2010
OBJECTIVE: To determine the role of intravenous administration of human albumin prior to blood exchange in term neonates for reduction of total serum bilirubin (TSB). DESIGN: Randomized controlled trial. SETTING: Neonatal Unit of Nemazee Hospital, affiliated with Shiraz University of Medical Sciences, southern Iran. PATIENTS: Fifty out-born term neonates with ...
Mehraien A - - 2009
We evaluate the effect of topical application of aprotinin to the heart, pericardia and mediastinum before sternal closure, on early post operative bleeding, blood transfusion requirement and ICU staying time after coronary artery bypass graft surgeries. In a randomized double blinded clinical trial, 128 patients who were scheduled for elective ...
Modan-Moses Dalit - - 2009
PURPOSE: Leptin and interleukin-6 (IL-6) are inversely correlated and associated with decreased survival in critically ill patients. We investigated changes in leptin, IL-6, and troponin in children undergoing open-heart surgery, hypothesizing that IL-6 and troponin will increase after cardiopulmonary bypass (CPB) and will be negatively correlated with leptin. PATIENTS AND ...
Raga Francisco - - 2009
OBJECTIVE: To evaluate the hemostatic efficacy and handling of gelatin-thrombin matrix in abdominal myomectomy. DESIGN: Prospective and randomized trial. SETTING: University teaching hospital. PATIENT(S): Women (n = 50) with uterine fibroids with a uterine size equivalent to > or =16 weeks gestation. INTERVENTION(S): Gelatin-thrombin matrix (FloSeal Matrix; Baxter Healthcare Corp., ...
Turner Jeff M - - 2009
BACKGROUND: There are scant data regarding the relative efficacy of exchange transfusion (XC) versus simple transfusion (ST) for treatment of sickle cell anemia acute chest syndrome (ACS). STUDY DESIGN AND METHODS: Twenty patients who received XC for ACS were compared with 20 ST patients. Hemoglobin (Hb) levels, platelet and white ...
Weis Florian - - 2009
BACKGROUND: Severe systemic inflammation (systemic inflammatory response syndrome) associated with cardiac surgery often leads to a worse short-term and long-term outcome. Stress doses of hydrocortisone have been successfully used to improve outcome of CS. The interleukin (IL)-6 to IL-10 ratio is associated with outcome after trauma and major surgery. OBJECTIVE: ...
Zhao Ju - - 2009
The benefits of pulsatile over nonpulsatile perfusion has been widely debated in pediatric cardiac operations with cardiopulmonary bypass (CPB). To evaluate the role of pulsatile perfusion in pediatric complicated patients with congenital heart disease undergoing open heart surgery, we performed pulsatile CPB and compared several effects with nonpulsatile perfusion. Pediatric ...
Lenoir Brigitte - - 2009
BACKGROUND: The aim of this study was to generate a score based on preoperative characteristics and predictive of the individual probability of allogeneic erythrocyte transfusion in patients undergoing elective thoracolumbar spine surgery. METHODS: Two hundred thirty consecutive patients were retrospectively included over a 15-month period (derivation set). Preoperative independent predictors ...
Zamani Farhad - - 2009
Major thalassemia is one of the most common hemoglobinopathies in many Asian countries including Iran. Pharmacologic agents such as hydroxyurea have been known to enhance the production of fetal hemoglobin, and also an increase in total hemoglobin level has been repeatedly reported during hydroxyurea treatment in patients with sickle cell ...
Leal-Noval Santiago R - - 2010
BACKGROUND: Both surgical insult and red blood cell transfusion (RBCT) induce alterations in type-1/type-2, CD4T-helper cell balance. This study was aimed to determine the influence of RBCT on Th1 and Th2 function immune response in cardiac surgery patients. MATERIAL AND METHODS: Three blood samples were prospectively drawn from 81 cardiac ...
Daryapeyma A - - 2009
The aim of this pilot study was to evaluate the clinical utility of quantitative CD64 measurements to differentiate between systemic inflammation in response to surgical trauma and postoperative bacterial infection. In a consecutive series of 153 patients undergoing elective vascular surgery, peripheral venous blood samples were taken preoperatively on admission ...
Nishio Nobuhiro - - 2009
Although the known clinical courses of non-severe aplastic anemia (NSAA) in children comprise spontaneous resolution, persistent NSAA, or progression to severe aplastic anemia (SAA), only a few published reports have indicated the outcome of transfusion-independent NSAA. We retrospectively evaluated the incidence and time of progression from transfusion-independent to transfusion-dependent NSAA ...
Castiglioni Alessandro - - 2009
To evaluate the clinical results of aortic valve replacement performed with a miniaturized closed circuit extracorporeal circulation (MECC) system and to compare it to standard cardiopulmonary bypass (CPB). One hundred and twenty consecutive patients undergoing isolated aortic valve replacement were randomly assigned to either a miniaturized closed circuit CPB with ...
Arezoomand Majid - - 2009
The full symmetry groups of carbon nanotori are investigated. It is shown that that the symmetry group of a chiral (n1, n2) nanotorus is isomorphic to D(2mq/n), where m and q are the number of lattice points on the torus circumference vector and the number of graphene hexagons in the ...
El Kady Nahla - - 2009
BACKGROUND AND OBJECTIVE: Primary brain tumours may be associated with coagulation disorders, which can pose intraoperative and postoperative management difficulties. Thromboelastography is a useful technique for evaluating coagulability. In this study, we evaluated the perioperative coagulation profile using both standard laboratory work and thromboelastography in paediatric patients undergoing craniotomy for ...
Biancari F - - 2009
OBJECTIVES: The aim of this meta-analysis is to summarise the results of prospective, randomised studies comparing miniaturised (Mini-CPB) versus conventional cardiopulmonary bypass (C-CPB). DESIGN: Meta-analysis of randomised trials. METHODS: After retrieval from literature search of 33 comparative studies, 13 studies have been included in this meta-analysis. RESULTS: There were 562 ...
Iskesen Ihsan - - 2009
BACKGROUND: Cardiopulmonary bypass may lead to many inflammatory responses that may cause myocardial dysfunction after open heart surgery. We aimed to investigate the effect of preoperative pentoxifylline treatment to reduce the occurrence of cardiopulmonary bypass-induced inflammatory response. METHODS: In a prospective, randomized study, 40 patients undergoing coronary artery bypass graft ...
Ghosh S - - 2009
A prospective hospital based blinded study was carried out in an orthopedics department in a medical college hospital of Kolkata, West Bengal, India, with the objective of assessing the role of pre-operative high-sensitivity C-reactive protein (hsCRP) level in predicting postoperative complications in replacement arthroplasty. One hundred and twenty one study ...
Gupta Sampa Dutta - - 2009
Hypomagnesaemia is a common complication after cardiopulmonary bypass (CPB) and predisposes to the development of cardiac arrhythmias. Previous studies showed that intravenous magnesium reduces the incidence of postoperative cardiac arrhythmias but it also inhibits platelet function. Our aim was to compare the postoperative blood loss in patients not receiving magnesium ...
Llewelyn C A CA National Blood Service (NBS)/Medical Research Council Clinical Studies Unit, NHS Blood and Transplant (NHSBT), Cambridge, - - 2009
Previous studies of blood use have used different methods to obtain and classify transfusion indications. Before undertaking a national study of transfusion recipients, a pilot study was performed over 2 months at two teaching and two district general hospitals to match information from hospital transfusion laboratories with clinical coding data ...
Tobian Aaron A R - - 2009
BACKGROUND: Mortality increases as hemoglobin (Hb) levels fall. Among severely anemic patients, the clinical course, cause of death, and whether there are any warning signs before death are unknown. STUDY DESIGN AND METHODS: A retrospective cohort study was performed of surgical patients who refused red blood cell transfusions for religious ...
Tempe Deepak K - - 2009
OBJECTIVE: To evaluate and compare early hemodynamic changes after elective mitral valve replacement (MVR) in patients with severe and mild pulmonary arterial hypertension (PAH). DESIGN: A prospective observational study. SETTING: University-affiliated hospital. PARTICIPANTS: Sixty patients undergoing elective MVR. INTERVENTIONS: The patients were divided into 2 equal groups based on the ...
Feng Jing - - 2009
To develop an intermittent hypoxia/reoxygenation (IH/ROX) rabbit carotid artery model and then investigate the inflammation status of rabbit carotid artery endothelium after IH exposure and its relationship with leptin. After anesthetization, rabbit's right common carotid artery was cleared of surrounding tissue with anatomic microscope, cannulated to its distal part and ...
Zehtabchi Shahriar - - 2009
OBJECTIVES: Coagulopathy is common after severe trauma and occurs very early after the initial insult. Some investigators have suggested early and aggressive treatment of the trauma-induced coagulopathy by transfusion of fresh-frozen plasma (FFP) and packed red blood cells (PRBC) in a 1:1 ratio. This evidence-based emergency medicine (EBM) review evaluates ...
Stager, Andrew Carl
The main purpose of this study was to determine the prognosis after Popliteal Artery Entrapment Syndrome (PAES) surgery for young, active individuals. The hypothesis was that after PAES surgery, full restoration of activity level and sport performance with improvements in exercise-induced leg pain (EILP) and activity tolerance occurs when the ...
Santarpino G - - 2009
AIM: Recent reports have shown anti-inflammatory effects with conventional hemofiltration (CUF) in patients undergoing cardiopulmonary bypass (CPB). The aim of this study was to evaluate the immunological and the hemodynamic response to CUF or metilprednisolone in patients undergoing coronary artery bypass grafting. METHODS: Twenty-four consecutive patients were prospectively randomized to ...
Yanagawa Youichi - - 2009
PURPOSE: The aim of this study was to investigate whether laboratory findings on arrival may be useful in predicting the outcome of out-of-hospital cardiopulmonary arrest (CPA). METHODS: Between January 2005 and September 2007, a medical chart review was retrospectively performed for CPA. The individual medical records were reviewed for the ...
Hudetz Judith A - - 2009
To determine if ketamine attenuates postoperative delirium concomitant with an anti-inflammatory effect in patients undergoing cardiac surgery using cardiopulmonary bypass. A prospective randomized study. A Veterans Affairs medical center. Cardiac surgical patients. Patients at least 55 years of age randomly received placebo (0.9% saline, n = 29) or an intravenous ...
Pehlivan Berrin - - 2009
AIM: To assess the influence of hemoglobin (Hb) levels in locally advanced head and neck cancer (LAHNC) patients treated with surgery and postoperative radiotherapy (PORT). MATERIAL AND METHODS: Pre- and postoperative Hb levels were collected in 79 patients treated with surgery followed by accelerated PORT for LAHNC. Median follow-up was ...
Abrishami Amir - - 2009
PURPOSE: This systematic review aimed to evaluate the efficacy and safety of topical application of antifibrinolytic drugs to reduce postoperative bleeding and transfusion requirements in patients undergoing on-pump cardiac surgery. METHODS: We searched The Cochrane Library, MEDLINE, EMBASE and SCI-EXPANDED for all randomized controlled trials on the topic. Trial inclusion, ...
Choudhary Dharma R - - 2009
OBJECTIVE: To assess the efficacy of wheat grass juice on transfusion requirement in patients with beta thalassemia major. METHODS: Fifty-three patients of thalassemia major with a median age of 16 years were given wheat grass juice tablets. RESULTS: The Mean pre and post wheat grass therapy, the pack cell requirement ...
Gonzalez-Porras J R - - 2009
We have prospectively evaluated the efficacy of an individualized pre-operative blood saving protocol in elective total hip arthroplasty (THA) or total knee arthroplasty (TKA). The primary aim was to obtain a pre-operative haemoglobin (Hb) level of > or =14 g dL(-1). A reduction in requirements for allogeneic transfusion was considered ...
Freilich Daniel - - 2009
BACKGROUND: Vasoactivity has hampered progress of hemoglobin-based oxygen carriers (HBOCs) due to concern for adverse blood pressure responses and secondary complications. A recent formulation, highly polymerized HBOC-201 (Biopure, Cambridge, MA), has been found to be less vasoactive than prior less polymerized formulations, and to improve outcome in animal models of ...
Guzzetta Nina A - - 2009
BACKGROUND: Recent concern about the safety of aprotinin administration to adults has led to its suspension from worldwide markets. However, few studies have examined its safety in pediatric patients. Studies in children evaluating aprotinin's safety have been hindered by the heterogeneity of pediatric patients and the inconsistency of clinical protocols. ...
Dohner M Lynn - - 2009
BACKGROUND: In neonatal intensive care unit (NICU) practice, a small percentage of the patients receive a large proportion of the platelet (PLT) transfusions administered. This study sought to better define this very-high-user group. To accomplish this, records of all NICU patients in a multihospital health care system who, during a ...
Ghazy Tamer - - 2009
The aim of this work was to question the necessity of repeated administration of warm blood cardioplegia in modern cardiac surgery. A consecutive series of 4014 patients underwent cardiosurgical procedures in the period from January 2001 to December 2006 in our centre, where modified Calafiore warm blood-cardioplegic solution was used. ...
Svagzdiene Milda - - 2009
OBJECTIVE: Our study was designed to assess the incidence of atrial fibrillation, changes in serum electrolyte concentrations and urinary electrolyte excretion following coronary artery bypass grafting surgery. MATERIAL AND METHODS: A total of 165 patients who underwent elective coronary artery bypass grafting surgery at the Department of Cardiac Surgery (Heart ...
< 2 3 4 5 6 7 8 9 10 11 12 >