Search Results
Results 1 - 50 of 1955
1 2 3 4 5 6 7 8 9 10 >
Zhong Wen W Department of Urology, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, - - 2014
Introduction: Mini percutaneous nephrolithotomy (mini-PCNL) and retrograde intrarenal surgery (RIRS) are well-established techniques with little morbidity. The combined use of standard PCNL and the mini-PCNL or the RIRS technique was evaluated and compared to investigate their own role in the management of staghorn calculi in solitary kidney. Materials and Methods: ...
Petek-Balc─▒ Belgin B 1Department of Neurology, Haseki Educational and Research Center , Istanbul , - - 2014
ABSTRACT Background: In a previous study, we had evaluated short-term effects of interferon beta-1a (IFNB-1a) 44 μg s.c. three times per week treatment on serum levels of IFN-gamma (IFNG), IL-23, IL-17, IL-10, IL-9, IL-4 and TGF-beta (TGFB) and found a reduction only in IL-17 and IL-23 levels after 2 months of ...
Makris Mike M Department of Cardiovascular Science, University of Sheffield; Sheffield Haemophilia and Thrombosis Centre, University of - - 2014
Vitamin K antagonists have been the main oral anticoagulants in use worldwide for more than 50 years. They are highly effect in preventing recurrence of venous thromboembolism and thrombotic stroke in patients with atrial fibrillation (1, 2). Despite this high degree of efficacy they have a number of limitations including ...
Al-Hashel Jasem J Department of Neurology, Ibn Sina Hospital, P.O. Box 25427, 13115, Safat, - - 2014
Fingolimod is an oral sphingosine-1-phosphate-receptor modulator, which has demonstrated efficacy in clinical trials and has recently been approved for multiple sclerosis (MS) treatment in Kuwait. Post-marketing studies are important to demonstrate real-life efficacy and safety. The objective of this study was to examine the efficacy and safety of fingolimod treatment ...
Tuleasca Constantin C Functional and Stereotactic Neurosurgery Unit, INSERM U 751, Assistance Publique-Hôpitaux de Marseille, Marseille, - - 2014
Background: Trigeminal neuralgia (TN) related to multiple sclerosis (MS) is more difficult to manage pharmacologically and surgically. Objective: This article aims to evaluate the safety and efficacy of Gamma Knife surgery (GKS) in this special group of patients. Methods: Between July 1992 and November 2010, 43 cases with more than ...
Park Hyoung-Chul HC Department of Surgery, Hallym University College of Medicine, 896 Pyeongchon-dong, Dongan-gu, Anyang, 431-070, Republic of - - 2014
Most patients with acute right colonic uncomplicated diverticulitis can be managed conservatively. The aim of this study was to assess the clinical and radiologic risk factors for recurrence in patients with right colonic uncomplicated diverticulitis. The present survey included 469 patients who were successfully managed conservatively for the first episode ...
Giallafos Ilias I First Cardiac Department, University of Athens, Athens, University of Athens, Athens, - - 2014
Atrial fibrillation (AF) is common in patients with systemic sclerosis (SSc) and is associated with significant morbidity, mortality, and healthcare expenditures. The aim of this study was to prospectively determine the incidence and the independent predictors of AF in this patient population. Forty-nine patients (age 50.15 ± 9.25 years, 87.8% ...
Clerico Marinella M Division of Neurology, Department of Clinical and Biological Sciences, University of Turin, San Luigi Gonzaga University Hospital, Orbassano, - - 2014
The evaluation of therapeutic choices is needed after 24 doses of natalizumab in patients with multiple sclerosis (MS). To evaluate the effect of therapeutic choices on the mean annualized relapse rate and on magnetic resonance imaging MS activity after 24 doses of natalizumab in patients with relapsing-remitting MS. The TY-STOP ...
Siddiqui Adnan H AH From the Departments of Neurosurgery and Radiology, The Jacobs Neurological Institute (A.H.S., Y.K., M.L.H., E.I.L., L.N.H.), and the Departments of Neurology (R.Z., R.H.B.B., D.W.H., B.W.-G.), Biostatistics (J.Y.), and Pharmaceutical Sciences (M.R.), University at Buffalo, State University of New York; and the Buffalo Neuroimaging Analysis Center (R.Z., K.L.M., V.V., C.L.K., D.P.R., K.D., E.C.), NY. asiddiqui@ubns.com - - 2014
We report the results of the investigation of safety and efficacy of venous angioplasty in patients with multiple sclerosis (MS) with findings of extracranial venous anomalies, considered hallmarks of chronic cerebrospinal venous insufficiency (CCSVI), in a 2-phase study (ClinicalTrials.gov NCT01450072).METHODS: Phase 1 was an open-label safety study (10 patients); phase ...
Rupprecht Martin M *Department of Pediatric Orthopaedics, The Altona Children's Hospital Departments of †Orthopaedics ‡Trauma-, Hand-, and Reconstructive Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, - - 2014
Temporary screw epiphysiodesis of the distal tibia is employed to correct ankle valgus deformity in patients with a wide spectrum of underlying etiologies. For patients with hereditary multiple exostosis it is unclear whether a rebound phenomenon may play a role after screw removal (SR) and successful management of ankle valgus ...
Lubelski Daniel D Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio, USA Cleveland Clinic; Center for Spine Health, Cleveland Clinic, Cleveland, Ohio, USA Department of Neurological Surgery, Cleveland Clinic, Cleveland, Ohio, - - 2014
Differentiating between MS and CS can be difficult because of their overlapping symptoms. While studies have shown preoperative imaging criteria that are predictive of outcomes in either MS or CS individually, no studies have investigated these factors in patients that have concurrent MS and CS. To investigate the associations between ...
van Pesch Vincent V Neurology Department, Cliniques Universitaires St-Luc, Avenue Hippocrate 10, 1200, Woluwe-Saint-Lambert, Belgium, - - 2014
Natalizumab (Tysabri(®)) is highly efficacious in controlling disease activity in relapsing multiple sclerosis (MS) patients. As it is one of the more recent therapies for MS, there remains a need for long-term safety and efficacy data of natalizumab in a clinical practice setting. The Tysabri observational program (TOP) is an ...
Ha Kee-Yong KY Department of Orthopaedic Surgery, Seoul St. Mary's Hospital College of Medicine, The Catholic University of Korea, Seoul, - - 2014
Study Design. Retrospective cohort studyObjective. To investigate the fate of sclerosis and anterior osteophytes in the fused segments after instrumented lumbar fusion for degenerative lumbar disorders.Summary of Background Data. Sclerosis and osteophytosis are well-known radiographic findings, but little is known of their significance with regard to spontaneous resorption after spine ...
Yoong Philip P Department of Radiology, Nuffield Orthopaedic Centre, Windmill Road, Headington, Oxford, OX3 7LD, UK, - - 2014
To assess whether there is a significant difference in the ischiofemoral space in patients with multiple hereditary exostoses affecting the proximal femora compared to normal patients. Ischiofemoral impingement is an increasingly recognized cause of hip and buttock pain. This causes narrowing of the ischiofemoral space resulting in an abnormal quadratus ...
Mohanty Sanghamitra S Texas Cardiac Arrhythmia Institute, St. David's Medical Center, Austin, Texas; College of Natural Sciences, University of Texas at Austin, - - 2014
Metabolic syndrome (MS) and obstructive sleep apnea (OSA) are well-known independent risk factors for AF recurrence. This study evaluated ablation-outcome in AF patients with coexistent MS and OSA and influence of life-style modifications (LSM) on arrhythmia-recurrence. We included 1257 AF patients undergoing first catheter ablation [30% paroxysmal AF]. Patients having ...
Fernandes Daniela Alves DA Neuroimaging Laboratory, Hospital de Clínicas, 2° Floor, MRI Unit, Rua Vital Brasil, 251, University of Campinas, UNICAMP, Cidade Universitária Zeferino Vaz, 13083-888 Campinas, SP, - - 2014
This study aimed to evaluate long-term atrophy in contralateral hippocampal volume after surgery for unilateral MTLE, as well as the cognitive outcome for patients submitted to either selective transsylvian amygdalohippocampectomy (SelAH) or anterior temporal lobe resection (ATL). We performed a longitudinal study of 47 patients with MRI signs of unilateral ...
Papanastassiou Ioannis D ID Neurosurgical Department, H. Lee Moffitt Cancer Center, Tampa, FL, USA. ; General Oncological Hospital "Agioi Anargyroi", Athens, - - 2014
Retrospective comparative study and technical note. To determine if there is a difference in clinical and radiographic parameters between unilateral and bilateral kyphoplasty in a uniform cancer population and to stress the importance of preoperative planning. While unipedicular kyphoplasty is gaining popularity, a few comparative studies have reported on superior ...
Biondo G G Unit of Dermatology and Cosmetology, San Raffaele Scientific University Institute, Milan, - - 2014
Tuberous sclerosis (TS) is a genodermatosis characterized by facial angiofibromas (FAs). These tumours cause aesthetic disfigurement and obstruction of vision, and haemorrhage when traumatized, which can lead to emotional distress and relationship difficulties. We report the case of a 35-year-old patient with extensive TS-associated FAs that were treated with an ...
Batlle Montserrat M Clinical Haematology Department, Institut Català d'Oncologia-Hospital Germans Trias i Pujol, José Carreras Research Institute, Badalona, - - 2014
Oral mucositis (OM) is a common complication of conditioning regimens with high dose melphalan (HDmel). This retrospective cohort study analyzes the impact of oral cryotherapy (OC) or room temperature saline rinses on the prevention of OM in patients with multiple myeloma (MM) or lymphoid neoplasias submitted to autologous stem cell ...
Gueguen Antoine A Department of Neurology, Fondation Ophtalmologique A. de Rothschild, Paris, - - 2014
To characterise recurrence of multiple sclerosis (MS) inflammatory activity during the year following natalizumab (NTZ) cessation. Thirty-two patients with MS were included in a monocentric cohort study. Data were collected prospectively during and after NTZ, with serial clinical and MRI evaluations. The first relapse occurring after interrupting NTZ was the ...
Reinink Hendrik H Department of Otorhinolaryngology-Head and Neck Surgery, University Medical Center Utrecht, the - - 2014
To evaluate the effect of repeated application of the Epley maneuver on patient-reported symptom relief and resolution of nystagmus in patients with posterior benign paroxysmal positional vertigo (p-BPPV). PubMed, Embase, and the Cochrane Library. A systematic search was conducted. Studies reporting original study data were included. Relevance and risk of ...
Rossi Silvia S Clinica Neurologica, Dipartimento di Medicina dei Sistemi, Università Tor Vergata, & Centro Europeo per la Ricerca sul Cervello (CERC)/Fondazione Santa Lucia, Rome, - - 2014
Natalizumab (NTZ) discontinuation leads to multiple sclerosis (MS) recurrence, but represents the only known strategy to limit the risk of progressive multifocal leukoencephalopathy (PML) in JCV seropositive patients. Here, we compared the clinical and imaging features of three groups of patients who discontinued NTZ treatment. We treated 25 patients with ...
Hoepner Robert R St Josef-Hospital, Ruhr-University, - - 2014
Risks of natalizumab (NAT) therapy have to be weighed against disease recurrence after stopping NAT. The objective of this paper is to identify risk factors for recurrence of relapses after switching from NAT to fingolimod (FTY) in relapsing-remitting multiple sclerosis (RRMS). Patients (n = 33) were treated with NAT for ...
Baldi Eleonora E Neurology Unit, Department of Neuroscience/Rehabilitation, Azienda Ospedaliera-Universitaria S. Anna, Ferrara, - - 2014
Abstract Objective: Fingolimod (FTY) is licensed as a disease-modifying treatment in highly active Relapsing-Remitting Multiple Sclerosis. The aim of the study was to evaluate the efficacy and safety of FTY in a real-life setting and to explore the possible role of clinical and MRI parameters, including previous treatment type, in ...
Napolitano Mariasanta M aHematology Unit, Thrombosis and Hemostasis Reference Regional Center, University of Palermo, Palermo bDivision of Endovascular and Vascular Surgery, Clinic GEPOS Telese Terme, Benevento, Italy cFaculty of Medicine, University of Campobasso, Campobasso dDivision of Neurology, Second University of Naples (SUN), Napoli, - - 2014
We performed a monocentric observational prospective study to evaluate coagulation activation and endothelial dysfunction parameters in patients with multiple sclerosis undergoing endovascular treatment for cerebro-spinal-venous insufficiency. Between February 2011 and July 2012, 144 endovascular procedures in 110 patients with multiple sclerosis and chronical cerebro-spinal venous insufficiency were performed and they ...
Kim J H JH Division of Infectious Diseases, Department of Internal Medicine, University of Utah, Salt Lake City, Utah, - - 2014
Levofloxacin is routinely used for the prevention of invasive bacterial infections during autologous peripheral blood stem cell transplantation (APBSCT). However, increasing rates of bacterial sepsis were noted at our institution among multiple myeloma (MM) patients undergoing outpatient APBSCT with melphalan-based chemotherapy and levofloxacin prophylaxis. We assessed the impact of a ...
Kang Ho Won HW Department of Urology, College of Medicine, Chungbuk National University, Cheongju, Republic of - - 2014
To characterize the clinical and metabolic abnormalities of patients presenting with multiple stones and determine their risk of new stone formation. This retrospective case-controlled study consisted of 911 patients who had ureter stones for the first time and 107 age- and sex-matched patients without stones. The patients were classified into ...
Lee Dong Yeon DY *Division of Pediatric Orthopaedics, Seoul National University Children's Hospital, Seoul †Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Seongnam, Republic of - - 2014
Hereditary multiple exostoses (HME) patients frequently present with ankle valgus deformity and marked fibular shortening. Loss of the lateral buttress may cause translational talus instability (TTI) that manifests as ankle pain after physical exercise, medial clear space widening on plain radiographs, and gross translational movement of the talus within the ...
Cohen Mikael M Department of Neurology, University Hospital of Nice, Nice, - - 2014
The safety and efficacy of switching from natalizumab to fingolimod have not yet been evaluated in a large cohort of patients with multiple sclerosis (MS) to our knowledge. To collect data from patients with MS switching from natalizumab to fingolimod. The Enquête Nationale sur l'Introduction du Fingolimod en Relais au ...
Lee Hwa H From the *Department of Ophthalmology, Korea University College of Medicine, Ansan; †Department of Ophthalmology, KEPCO Medical Center, Seoul; and ‡Department of Ophthalmology, Dongguk University Ilsan Hospital, Goyang, South - - 2014
This study was undertaken to evaluate the clinical characteristics and efficacy of the lateral tarsal strip (TS) and medial spindle procedure (MS). We conducted a retrospective chart review of the patients who underwent TS and MS between September 2008 and July 2011 by a single surgeon (S.H.B.). Data were collected ...
Jackson Graham H GH University of Newcastle, Newcastle-upon-Tyne, - - 2014
Bisphosphonates are recommended in patients with osteolytic lesions secondary to multiple myeloma. We report on the safety of bisphosphonate therapy with long-term follow-up in the Medical Research Council Myeloma IX study. Patients with newly diagnosed multiple myeloma were randomised to zoledronic acid (ZOL; 4 mg intravenously every 21-28 d) or clodronate (CLO; ...
Hosokawa Yukinari - - 2014
To evaluate the clinical usefulness of estimated glomerular filtration rate (eGFR) divided by functional renal volume (FRV) measured by three-dimensional image reconstruction (eGFR/FRV) for the prediction of functional outcomes after nephrectomy. Eighty-three patients who underwent nephrectomy were enrolled. The FRV of each patient was measured before surgery. Preoperative medical information ...
Moldoveanu C C "Saint John" Emergency Clinical Hospital, Department of - - 2014
A long term, retrospective study was performed aiming to outline a critical comparison concerning the efficacy, safety and durability of the bipolar plasma vaporization (BPV), standard monopolar transurethral resection (TUR) and "cold-knife" "star" transurethral incision (TUI) in secondary bladder neck sclerosis (BNS) cases. Materials & Methods: Of the 126 patients ...
Valenzuela Reuben Mari RM Department of Neurology, University of Illinois College of Medicine, Illinois Neurologic Institute, Department of Medicine, Peoria, United - - 2014
Natalizumab was approved in 2004 by the US Food and Drug Administration (US-FDA) for treatment of multiple sclerosis (MS), however it was temporarily withdrawn after its use was associated with progressive multifocal leukoencephalopathy (PML). Other reported adverse events have included melanoma, primary central nervous system (CNS) lymphoma, and gastrointestinal cryptosporidiosis. ...
Najmi Varzaneh Fatemeh F Sina MS Research Center, Neuroscience Institute, Sina Hospital, Tehran University of Medical Sciences, Tehran, - - 2014
Multiple sclerosis (MS) is a multifaceted disease in which genetic and environmental factors are involved. Although neurodegeneration aspect of MS has major influence in patients' disability, none of the available treatments have been shown to obviously reduce neurodegeneration. Recently, the role of Erythropoietin (EPO) as a neuroprotective and anti-inflammatory agent ...
Lee Seung Yeol SY Department of Orthopaedic Surgery, Mongji Hospital, Kyungki, Republic of - - 2014
Although several studies have reported on the outcomes of rectus femoris transfer (RFT), few have investigated the multiple factors that could affect the results. Therefore, we evaluated the outcomes of RFT and analyzed factors that influence improvement and annual change in knee motion after surgery in patients with cerebral palsy ...
Kaffes Arthur A Royal Prince Alfred Hospital - AW Morrow Gastroenterology and Liver Centre, Missenden Road, Camperdown, Sydney, New South Wales 2050, - - 2014
Post-liver-transplant biliary anastomotic strictures (ASs) are currently managed with repeated endoscopic retrograde cholangiopancreatographies (ERCPs) inserting multiple plastic stents. Fully covered self-expanding metal stents (FCSEMSs) are being increasingly reported in the management of this condition, however no prospective randomized trials have been performed to date. The aim of this study was ...
Deshpande Aniruddha - - 2014
Today's patients are increasingly conscious of personal appearance, and much attention has been focused on denuded roots that are exposed during smiling. These concerns have given rise to numerous approaches for covering denuded root surfaces. Therefore, this study was undertaken to compare the effectiveness of recombinant human platelet-derived growth factor ...
Owman Henrik H Department of Orthopaedics, Clinical Sciences, Malmö, Lund University, Sweden. Electronic address: - - 2014
To examine the association between the relaxation time (T1Gd) of delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) and grade of tibiofemoral joint space narrowing (JSN) and osteophytosis 11 years later, in a cohort of meniscectomized patients. Patients (n = 45) aged 35-50 who had undergone an arthroscopic partial medial meniscectomy 1-6 ...
Müller Patrick P University Hospital Bergmannsheil Bochum, Bochum, NRW Bürkle-de-la-Camp Platz 1 44787, - - 2014
Previously we identified total atrial conduction time (TACT) assessed via PA-TDI interval as a non-invasive marker to reflect the degree of atrial remodeling. The aim of this study was to determine whether PA-TDI interval is an independent predictor of recurrent atrial fibrillation (AF) and if it reflects reverse atrial remodeling ...
Kakar S S Department of Orthopaedic Surgery, Mayo Clinic, Rochester MN, - - 2014
Painful radioulnar convergence following resection of the distal ulna can produce substantial disability and prove a challenging surgical problem, particularly in the revision setting. The purpose of this study was to evaluate the outcome of a series of patients with chronic distal radioulnar joint instability or multiple prior procedures treated ...
Shima Yoshihito Y Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine , 2-2 Yamada-oka, 565-0871, Suita City, Osaka , - - 2014
Abstract Systemic sclerosis (SSc) presents stiffness of extremities due to sclerosis of the tissue especially at fingers, hands, and forearms. Here we report the case of a patient with diffuse cutaneous SSc who was administered anti-interleukin-6 receptor antibody tocilizumab (TCZ). Skin condition of SSc is evaluated by pinching the skin ...
Topart Philippe P Société de Chirurgie Viscérale, Clinique de l'Anjou, 142, avenue de Lattre de Tassigny, 49000 Angers, France. Electronic address: - - 2014
Malabsorptive bariatric procedures require multiple vitamin supplements, especially regarding fat-soluble vitamins. The exact amount required to maintain normal serum concentrations is still largely unknown. Based on the initial postoperative prescription, we assessed the number of adjustments and the amount of vitamins/micronutrients to normalize the biological markers 2 years after the ...
Butzkueven Helmut H Department of Medicine, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, , Melbourne, Victoria, - - 2014
Clinical trials established the efficacy and safety of natalizumab. Data are needed over longer periods of time and in the clinical practice setting. To evaluate long-term safety of natalizumab and its impact on annualised relapse rate and Expanded Disability Status Scale (EDSS) progression in patients with relapsing-remitting multiple sclerosis (RRMS). ...
Scalise Filippo F Cardiac and Vascular Catheterization Laboratory, Policlinico di Monza, Monza, - - 2014
Chronic cerebrospinal venous insufficiency (CCSVI) is a vascular condition characterized by anomalies of the internal jugular veins (IJVs) and/or azygos veins with disturbed flow and formation of collateral venous channels. The presence of CCSVI has been associated with multiple sclerosis (MS). Percutaneous venous angioplasty (PVA) has been proposed to improve ...
Flachenecker Peter P Neurological Rehabilitation Center Quellenhof, Bad Wildbad, - - 2014
Background: Nabiximols (Sativex®), a cannabinoid-based oromucosal spray, is an add-on therapy for patients with moderate to severe multiple sclerosis spasticity (MSS) resistant to other medications. The primary objective was to provide real-life observational data of clinical experience of nabiximols in contrast to formal clinical trials of effectiveness. Methods: This was ...
Frisullo Giovanni G Department of Neurosciences, Catholic University of Rome, - - 2014
Few long-term follow-up data are available on thyroid dysfunction (TD) in multiple sclerosis (MS) patients treated with glatiramer acetate (GA) or with interferon-beta (IFNb). In a cohort of 787 relapsing-remitting MS (RRMS) patients whom were followed up for 8 years, we observed an increased prevalence of TD and thyroid autoimmunity ...
Wójcik Maciej M Department of Cardiology, Kerckhoff Heart and Thorax Center, Bad Nauheim, Germany; Department of Cardiology, Medical University of Lublin, Lublin, - - 2014
Catheter ablation (CA) of atrial fibrillation (AF) is now established therapeutic option. Multiple procedures (MPs) are often needed to achieve the satisfactory outcome. The aim of the study was to assess the outcome after MPs in AF patients categorized to risk-score groups. We followed a cohort of consecutive 911 (69% ...
Macrae Phoebe - - 2014
PURPOSE This study examined the effects of chin-down swallowing on laryngeal vestibule closure. It also investigated the technique's rehabilitative impact, by assessing the stability of effects across multiple trials and after-effects in neutral swallows on cessation of the technique METHOD Duration of laryngeal vestibule closure (dLVC) was measured with videofluoroscopy ...
Kira Jun-Ichi - - 2014
A 6-month phase 2 study of fingolimod demonstrated efficacy and safety in Japanese patients with relapsing-remitting multiple sclerosis (MS). Here we report a 6-month observational extension that evaluated efficacy and safety in patients who received fingolimod continuously for 12 months or who switched from placebo to fingolimod. Of 147 patients ...
1 2 3 4 5 6 7 8 9 10 >