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Kang Ho Won HW Department of Urology, College of Medicine, Chungbuk National University, Cheongju, Republic of - - 2014
To characterize the clinical and metabolic abnormalities of patients presenting with multiple stones and determine their risk of new stone formation. This retrospective case-controlled study consisted of 911 patients who had ureter stones for the first time and 107 age- and sex-matched patients without stones. The patients were classified into ...
Lee Dong Yeon DY *Division of Pediatric Orthopaedics, Seoul National University Children's Hospital, Seoul †Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Seongnam, Republic of - - 2014
Hereditary multiple exostoses (HME) patients frequently present with ankle valgus deformity and marked fibular shortening. Loss of the lateral buttress may cause translational talus instability (TTI) that manifests as ankle pain after physical exercise, medial clear space widening on plain radiographs, and gross translational movement of the talus within the ...
Cohen Mikael M Department of Neurology, University Hospital of Nice, Nice, - - 2014
The safety and efficacy of switching from natalizumab to fingolimod have not yet been evaluated in a large cohort of patients with multiple sclerosis (MS) to our knowledge. To collect data from patients with MS switching from natalizumab to fingolimod. The Enquête Nationale sur l'Introduction du Fingolimod en Relais au ...
Lee Hwa H From the *Department of Ophthalmology, Korea University College of Medicine, Ansan; †Department of Ophthalmology, KEPCO Medical Center, Seoul; and ‡Department of Ophthalmology, Dongguk University Ilsan Hospital, Goyang, South - - 2014
This study was undertaken to evaluate the clinical characteristics and efficacy of the lateral tarsal strip (TS) and medial spindle procedure (MS). We conducted a retrospective chart review of the patients who underwent TS and MS between September 2008 and July 2011 by a single surgeon (S.H.B.). Data were collected ...
Jackson Graham H GH University of Newcastle, Newcastle-upon-Tyne, - - 2014
Bisphosphonates are recommended in patients with osteolytic lesions secondary to multiple myeloma. We report on the safety of bisphosphonate therapy with long-term follow-up in the Medical Research Council Myeloma IX study. Patients with newly diagnosed multiple myeloma were randomised to zoledronic acid (ZOL; 4 mg intravenously every 21-28 d) or clodronate (CLO; ...
Hosokawa Yukinari - - 2014
To evaluate the clinical usefulness of estimated glomerular filtration rate (eGFR) divided by functional renal volume (FRV) measured by three-dimensional image reconstruction (eGFR/FRV) for the prediction of functional outcomes after nephrectomy. Eighty-three patients who underwent nephrectomy were enrolled. The FRV of each patient was measured before surgery. Preoperative medical information ...
Moldoveanu C C "Saint John" Emergency Clinical Hospital, Department of - - 2014
A long term, retrospective study was performed aiming to outline a critical comparison concerning the efficacy, safety and durability of the bipolar plasma vaporization (BPV), standard monopolar transurethral resection (TUR) and "cold-knife" "star" transurethral incision (TUI) in secondary bladder neck sclerosis (BNS) cases. Materials & Methods: Of the 126 patients ...
Valenzuela Reuben Mari RM Department of Neurology, University of Illinois College of Medicine, Illinois Neurologic Institute, Department of Medicine, Peoria, United - - 2014
Natalizumab was approved in 2004 by the US Food and Drug Administration (US-FDA) for treatment of multiple sclerosis (MS), however it was temporarily withdrawn after its use was associated with progressive multifocal leukoencephalopathy (PML). Other reported adverse events have included melanoma, primary central nervous system (CNS) lymphoma, and gastrointestinal cryptosporidiosis. ...
Najmi Varzaneh Fatemeh F Sina MS Research Center, Neuroscience Institute, Sina Hospital, Tehran University of Medical Sciences, Tehran, - - 2014
Multiple sclerosis (MS) is a multifaceted disease in which genetic and environmental factors are involved. Although neurodegeneration aspect of MS has major influence in patients' disability, none of the available treatments have been shown to obviously reduce neurodegeneration. Recently, the role of Erythropoietin (EPO) as a neuroprotective and anti-inflammatory agent ...
Lee Seung Yeol SY Department of Orthopaedic Surgery, Mongji Hospital, Kyungki, Republic of - - 2014
Although several studies have reported on the outcomes of rectus femoris transfer (RFT), few have investigated the multiple factors that could affect the results. Therefore, we evaluated the outcomes of RFT and analyzed factors that influence improvement and annual change in knee motion after surgery in patients with cerebral palsy ...
Kaffes Arthur A Royal Prince Alfred Hospital - AW Morrow Gastroenterology and Liver Centre, Missenden Road, Camperdown, Sydney, New South Wales 2050, - - 2014
Post-liver-transplant biliary anastomotic strictures (ASs) are currently managed with repeated endoscopic retrograde cholangiopancreatographies (ERCPs) inserting multiple plastic stents. Fully covered self-expanding metal stents (FCSEMSs) are being increasingly reported in the management of this condition, however no prospective randomized trials have been performed to date. The aim of this study was ...
Deshpande Aniruddha - - 2014
Today's patients are increasingly conscious of personal appearance, and much attention has been focused on denuded roots that are exposed during smiling. These concerns have given rise to numerous approaches for covering denuded root surfaces. Therefore, this study was undertaken to compare the effectiveness of recombinant human platelet-derived growth factor ...
Yang Chin-Yu CY Division of Reconstructive Microsurgery, Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung University, Collage of Medicine, Taoyuan, Taiwan; Division of Plastic and Reconstructive Surgery, Stanford University Medical Center, Palo Alto, Calif.; and Molecular Imaging Center, Chang Gung Memorial Hospital, Taoyuan, - - 2014
This study was aimed to establish a consistent lower limb lymphedema animal model for further investigation of the mechanism and treatment of lymphedema. Lymphedema in the lower extremity was created by removing unilateral inguinal lymph nodes followed by 20, 30, and 40 Gy (groups IA, IB, and IC, respectively) radiation ...
Owman Henrik H Department of Orthopaedics, Clinical Sciences, Malmö, Lund University, Sweden. Electronic address: - - 2014
To examine the association between the relaxation time (T1Gd) of delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) and grade of tibiofemoral joint space narrowing (JSN) and osteophytosis 11 years later, in a cohort of meniscectomized patients. Patients (n = 45) aged 35-50 who had undergone an arthroscopic partial medial meniscectomy 1-6 ...
Müller Patrick P University Hospital Bergmannsheil Bochum, Bochum, NRW Bürkle-de-la-Camp Platz 1 44787, - - 2014
Previously we identified total atrial conduction time (TACT) assessed via PA-TDI interval as a non-invasive marker to reflect the degree of atrial remodeling. The aim of this study was to determine whether PA-TDI interval is an independent predictor of recurrent atrial fibrillation (AF) and if it reflects reverse atrial remodeling ...
Kakar S S Department of Orthopaedic Surgery, Mayo Clinic, Rochester MN, - - 2014
Painful radioulnar convergence following resection of the distal ulna can produce substantial disability and prove a challenging surgical problem, particularly in the revision setting. The purpose of this study was to evaluate the outcome of a series of patients with chronic distal radioulnar joint instability or multiple prior procedures treated ...
Shima Yoshihito Y Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine , 2-2 Yamada-oka, 565-0871, Suita City, Osaka , - - 2014
Abstract Systemic sclerosis (SSc) presents stiffness of extremities due to sclerosis of the tissue especially at fingers, hands, and forearms. Here we report the case of a patient with diffuse cutaneous SSc who was administered anti-interleukin-6 receptor antibody tocilizumab (TCZ). Skin condition of SSc is evaluated by pinching the skin ...
Topart Philippe P Société de Chirurgie Viscérale, Clinique de l'Anjou, 142, avenue de Lattre de Tassigny, 49000 Angers, France. Electronic address: - - 2014
Malabsorptive bariatric procedures require multiple vitamin supplements, especially regarding fat-soluble vitamins. The exact amount required to maintain normal serum concentrations is still largely unknown. Based on the initial postoperative prescription, we assessed the number of adjustments and the amount of vitamins/micronutrients to normalize the biological markers 2 years after the ...
Scalise Filippo F Cardiac and Vascular Catheterization Laboratory, Policlinico di Monza, Monza, - - 2014
Chronic cerebrospinal venous insufficiency (CCSVI) is a vascular condition characterized by anomalies of the internal jugular veins (IJVs) and/or azygos veins with disturbed flow and formation of collateral venous channels. The presence of CCSVI has been associated with multiple sclerosis (MS). Percutaneous venous angioplasty (PVA) has been proposed to improve ...
Butzkueven Helmut H Department of Medicine, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, , Melbourne, Victoria, - - 2014
Clinical trials established the efficacy and safety of natalizumab. Data are needed over longer periods of time and in the clinical practice setting. To evaluate long-term safety of natalizumab and its impact on annualised relapse rate and Expanded Disability Status Scale (EDSS) progression in patients with relapsing-remitting multiple sclerosis (RRMS). ...
Flachenecker Peter P Neurological Rehabilitation Center Quellenhof, Bad Wildbad, - - 2014
Background: Nabiximols (Sativex®), a cannabinoid-based oromucosal spray, is an add-on therapy for patients with moderate to severe multiple sclerosis spasticity (MSS) resistant to other medications. The primary objective was to provide real-life observational data of clinical experience of nabiximols in contrast to formal clinical trials of effectiveness. Methods: This was ...
Frisullo Giovanni G Department of Neurosciences, Catholic University of Rome, - - 2014
Few long-term follow-up data are available on thyroid dysfunction (TD) in multiple sclerosis (MS) patients treated with glatiramer acetate (GA) or with interferon-beta (IFNb). In a cohort of 787 relapsing-remitting MS (RRMS) patients whom were followed up for 8 years, we observed an increased prevalence of TD and thyroid autoimmunity ...
Wójcik Maciej M Department of Cardiology, Kerckhoff Heart and Thorax Center, Bad Nauheim, Germany; Department of Cardiology, Medical University of Lublin, Lublin, - - 2014
Catheter ablation (CA) of atrial fibrillation (AF) is now established therapeutic option. Multiple procedures (MPs) are often needed to achieve the satisfactory outcome. The aim of the study was to assess the outcome after MPs in AF patients categorized to risk-score groups. We followed a cohort of consecutive 911 (69% ...
Macrae Phoebe - - 2014
PURPOSE This study examined the effects of chin-down swallowing on laryngeal vestibule closure. It also investigated the technique's rehabilitative impact, by assessing the stability of effects across multiple trials and after-effects in neutral swallows on cessation of the technique METHOD Duration of laryngeal vestibule closure (dLVC) was measured with videofluoroscopy ...
Kira Jun-Ichi - - 2014
A 6-month phase 2 study of fingolimod demonstrated efficacy and safety in Japanese patients with relapsing-remitting multiple sclerosis (MS). Here we report a 6-month observational extension that evaluated efficacy and safety in patients who received fingolimod continuously for 12 months or who switched from placebo to fingolimod. Of 147 patients ...
Prosperini Luca L S. Andrea Hospital, Sapienza University, Rome, - - 2014
Objectives: To investigate whether clinical and magnetic resonance imaging (MRI) outcomes of patients with multiple sclerosis (MS) who required a reduction of administration frequency of interferon-beta (IFNB) were similar to those of patients who did not. Methods: We identified three subgroups of patients under treatment for 24 months with subcutaneous ...
Wu Xingchen - - 2014
Objective: To evaluate the prognostic value of the cortical N-acetyl aspartate to creatine ratio (NAA/Cr) in early relapsing-remitting multiple sclerosis (RRMS). Methods: Sixteen patients with newly diagnosed RRMS were studied by serial MRI and MR spectroscopic imaging (MRSI) once every 6 months for 24 months. Clinical examinations, including the expanded ...
Ascherio Alberto A Harvard School of Public Health, Boston, - - 2014
IMPORTANCE It remains unclear whether vitamin D insufficiency, which is common in individuals with multiple sclerosis (MS), has an adverse effect on MS outcomes. OBJECTIVES To determine whether serum concentrations of 25-hydroxyvitamin D (25[OH]D), a marker of vitamin D status, predict disease activity and prognosis in patients with a first ...
Kim Yong-Kyu YK Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South - - 2014
To investigate the incidence and the clinical factors associated with the occurrence of multiple subretinal fluid (SRF) blebs after successful rhegmatogenous retinal detachment (RD) repair. Retrospective, observational case series METHODS: We retrospectively investigated the medical records of 185 eyes of 184 patients who had undergone successful RD surgery either vitrectomy ...
Shinozaki Satoshi S Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, - - 2014
GI bleeding secondary to small-intestine vascular lesions (SIVLs) is associated with rebleeding despite initial hemostasis by endotherapy applied at double-balloon endoscopy (DBE). To evaluate the long-term outcomes of DBE endotherapy of SIVL (as described by the Yano-Yamamoto classification). The impact of repeat DBE endotherapy for recurrent bleeding also was assessed. ...
Kul S S Department of Cardiology, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey. Electronic address: - - 2014
Metabolic syndrome (MS) is associated with cardiovascular mortality and morbidity in patients with acute coronary syndrome. The purpose of this study was to evaluate the impact of MS on long-term clinical outcomes in patients with pure non-ST segment myocardial infarction (NSTEMI) or unstable angina pectoris (USAP). We prospectively enrolled 310 ...
Shen Yonghua Y Department of Gastroenterology, The Affiliated Drum Tower Hospital of Nanjing University, Medical School, PR - - 2014
Refractory chronic pancreatitis has been proposed as a challenge for endoscopists following routine single plastic stenting. However, data on the efficacy and safety of further endoscopic stenting are still controversial. The current systematic review aimed to assess the efficacy and safety of placement of fully covered self-expandable metal stent (FCSEMS) ...
Korchounov A A Clinic of Neurology, Marienhospital Kevelaer, Kevelaer, - - 2014
Relapses in MS may affect the acquisition and maintenance of employment due to associated neurological deficits. Several disease modifying drugs (DMD) like interferons or glatiramer reduce the frequency of relapses and decrease their severity in MS. To investigate the influence of DMD on employment prevalence and employment rate with relapsing ...
Kamm Christian P CP Department of Neurology, Inselspital, University Hospital Bern and University of Bern, Bern, - - 2014
Statins have anti-inflammatory and immunomodulatory properties in addition to lipid-lowering effects. To report the 12-month extension of a phase II trial evaluating the efficacy, safety and tolerability of atorvastatin 40 mg/d added to interferon beta-1b (IFNB-1b) in relapsing-remitting multiple sclerosis (RRMS). In the randomized, multicenter, parallel-group, rater-blinded core study, 77 ...
Bryant Ayesha S AS Division of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, Ala. Electronic address: - - 2014
The objective of the present study was to determine the long-term fate and factors of compensatory hyperhidrosis (CH) in patients who have undergone video-assisted thoracoscopic sympathotomy for focal hyperhidrosis. The same quality-of-life survey was administered 6 months postoperatively and then annually to all patients who underwent Video-assisted thoracoscopic sympathotomy for ...
Schulze Maximilian M 1 Department of Diagnostic Radiology, Eberhard Karls University, Hoppe-Seyler-Strasse 3, 72076 Tübingen, - - 2014
OBJECTIVE. The objective of our study was to assess the frequency, location, extent, and patterns of bone sclerosis occurring in patients with multiple myeloma (MM) during bortezomib-based therapy. MATERIALS AND METHODS. From June 2003 through December 2011, 593 whole-body reduced-dose MDCT studies were performed of 79 consecutive patients receiving bortezomib. ...
Ngcozana Tanaka T Royal Free Hospital, London, - - 2014
Two patients with scleroderma and recurrent digital ulcers (DUs) were treated with bosentan for 6 months. Treatment was associated with a reduction in the number of new DUs; however, DUs recurred on treatment discontinuation. This case report illustrates the positive response of digital vasculopathy to bosentan and describes the benefits ...
Foocharoen Chingching - - 2014
To determine if there is any significant difference in the clinical characteristics and mortality between early-and late-referred systemic sclerosis (SSc). An historical cohort study was performed among referred-SSc patients at Srinagarind Hospital between January 2006 and December 2010. 'Early referrals'occurred during the edematous phase while 'late referrals' occurred after that. ...
Dalgas Ulrik U Department of Sport Science , University of Aarhus, Aarhus, Denmark. - - 2014
To examine the aerobic intensity level and pacing pattern during the 6-min walk test (6MWT) in persons with multiple sclerosis, taking into account time of day, fatigue, disability level and multiple sclerosis subtype. Cross-sectional study. Eighty multiple sclerosis patients (Expanded Disability Status Scale, EDSS ≤ 6.5). Participants performed the 6MWT at ...
Cardaropoli Daniele - - 2014
Multiple adjacent recession defects were treated in 32 patients using a coronally advanced flap (CAF) with or without a collagen matrix (CM). The percentage of root coverage was 81.49% ± 23.45% (58% complete root coverage) for CAF sites (control) and 93.25% ± 10.01% root coverage (72% complete root coverage) for ...
Ferrazzi Anna A Unit of Dermatology, University of Padua, Padova, - - 2014
A 54-year-old woman developed psoriasis on the plantar surface of her feet after 2 weeks of thalidomide 100 mg daily for the treatment of multiple IgG myeloma. She did not have any previous history of psoriasis. Thalidomide was immediately stopped and topical treatment with calcipotriol ointment and β-methasone valerate was started. Psoriasis ...
Sajad Wani W Department of Plastic Surgery, SKIMS, Srinagar, Jammu and Kashmir 190011, - - 2014
Background. Groin and perineal burn contracture is a rare postburn sequel. Such postburn contractures causes distressing symptoms to the patients and in the management of these contractures, both functional and cosmetic appearance should be the primary concern. Aims. To study the outcome of surgical treatment (STSG and multiple Z-plasties) in ...
Lin Hui H Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, - - 2014
Aims. We attempted to establish some guidelines for the selection of transmural stents during endoscopic drainage of PFCs by retrospective review of the clinical data obtained from three tertiary hospitals. Patients and Methods. Clinical data of 93 patients with attempted endoscopic drainage of symptomatic PFCs were obtained through chart review ...
Melea Pelagia I PI Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Alexandra General Hospital, 80 Vas. Sofias Avenue, 11528 Athens, - - 2014
The use of intravenous bisphosphonates (pamidronate or zoledronic acid) is the cornerstone for the management of multiple myeloma-(MM-) related bone disease. However, osteonecrosis of the jaw (ONJ) is a rare, but sometimes difficult to manage, adverse effect of bisphosphonates therapy. A retrospective review of all MM patients who were treated ...
Fiandra Christian C Radiation Oncology Departmen, University of Torino,Turin, Italy. - - 2014
The aim of this study is to evaluate the accuracy of daily prostate localization with ultrasound imaging of various radiation oncologists with nonhomogeneous expertise. For ten patients who underwent radical radiotherapy for localized prostate cancer, 11 radiation oncologists reviewed daily ultrasound scans acquired during three different treatment sessions. The average ...
Kong Moonkyoo M Department of Radiation Oncology, Kyung Hee University Medical Center, Kyung Hee University School of Medicine, Seoul, Republic of - - 2014
There have not yet been any published studies on the effects of laughter therapy on radiation-induced dermatitis in breast cancer patients treated with radiotherapy (RT). We assessed the effectiveness of laughter therapy in preventing radiation dermatitis in patients with breast cancer. Thirty-seven patients were prospectively enrolled in this study. Eighteen ...
Zucchelli G G Department of Biomedical and Neuromotor Sciences, Bologna University, - - 2013
The aim of this study was to compare short and long terms root coverage and aesthetic outcomes of the coronally advanced flap (CAF) alone or in combination with a connective tissue graft (CTG) for the treatment of multiple gingival recessions. 50 patients with multiple (≥2) adjacent gingival recessions (≥ 2mm) ...
Nagashima Koichi K 1Arrhythmia Unit, Cardiovascular Division, Brigham and Women's Hospital, Boston, - - 2013
-In the absence of overt structural heart disease most left ventricular outflow tract (LVOT) ventricular tachycardias (VTs) have a focal origin and are benign. We hypothesized that multiple morphologies (MM) of inducible LVOT VT may indicate a scar-related VT that can mimic idiopathic VT. -Of 54 consecutive patients referred for ...
Fioramonti Paolo P Department of Plastic and Reconstructive and Aesthetic Surgery, Sapienza University of Rome, Viale del Policlinico 155, 00161, Rome, - - 2013
Tuberous sclerosis, an autosomal dominant neurocutaneous syndrome seen in approximately 1 in 6,000 people worldwide, is characterized by the appearance of hamartomas in multiple organs. The classic clinical triad consists of angiofibromas, epilepsy, and developmental delay. Dermatologic disorder is one of the main characteristics. Angiofibromas, a common form of presentation, ...
Desai Aravind S - - 2013
Stiffness following total knee arthroplasty is a disabling complication. One of the management options of stiffness includes manipulation under anaesthesia, but no real consensus exist on appropriate timing of intervention, and the timing and results of the manipulation under anaesthesia (MUA) are under debate in the literature. Our aim was ...
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