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Ke Wang W Department of Urology, Yantai Yuhuangding Hospital , Yantai 264000, - - 2014
Objective: To investigate the safety and feasibility of self-retaining bidirectional barbed absorbable suture application in retroperitoneoscopic partial nephrectomy. Materials and Methods: From Sep 2011 and Aug 2012, 76 cases of retroperitoneoscopic partial nephrectomy were performed at our hospital. The patients were divided into two groups: self-retaining barbed suture (SRBS) group ...
Providência Rui R Département de Rythmologie, Clinique Pasteur, 45 avenue de Lombez, BP 27617, 31076 Toulouse Cedex 3, - - 2014
The recent availability of the novel oral anticoagulants (NOACs) may have led to a change in the anticoagulation regimens of patients referred to catheter ablation of atrial fibrillation (AF). Preliminary data exist concerning dabigatran, but information regarding the safety and efficacy of rivaroxaban in this setting is currently scarce.METHODS AND ...
Cagini Carlo C Department of Ophthalmology, University of Perugia - - - 2014
<p><bold>Purpose:</bold> To verify the efficacy to obtain mydriasis and cardiovascular safety of Mydriasert (ophthalmic insert containing tropicamide and phenylephrine) in diabetic and nondiabetic patients undergoing retinal angiography by comparing it with usually administered eyedrops (tropicamide 1% and phenylephrine 10%).</p><p><bold>Methods:</bold> This was a prospective randomized study. A total of 154 eyes ...
Sakamoto Tetsuya T Teikyo University School of Medicine, Tokyo, - - 2014
A favorable neurological outcome is likely to be achieved in out-of-hospital cardiac arrest (OHCA) patients with ventricular fibrillation or pulseless ventricular tachycardia (VF/VT) on the initial electrocardiogram (ECG). However, in patients without prehospital restoration of spontaneous circulation despite the initial VF/VT, the outcome is extremely low by conventional cardiopulmonary resuscitation ...
Overdevest Ep E 1Department of Extra-corporeal Circulation & Perioperative Blood Management, Catharina Hospital Eindhoven, Eindhoven, The - - 2014
The introduction of new and more advanced technology in healthcare occurs with an increasing speed. Therefore, more attention is needed for safety evaluation of new devices or techniques from an end-user perspective, especially when (inter-) national perfusion safety standards are lacking.A recently increased awareness of the safety risks as a ...
Malinova Vesna V Department of Neurosurgery, Georg-August-University, Robert-Koch-Straße 40, Göttingen, 37075, Germany, - - 2014
The optimal management of spontaneous intracerebral hemorrhage (ICH), especially if deep-seated, remains a matter of discussion. Lysis of the blood clot applying recombinant tissue-type plasminogen activator (rtPA) by an intrahematomal catheter is a minimally invasive treatment option, currently being under investigation in a randomized trial. The center position of the ...
Fesl Gunther G Department of Neuroradiology, Klinikum Grosshadern, University of Munich, Marchioninistr. 15, 81377, Munich, Germany, - - 2014
Multiple endovascular devices have been used for mechanical thrombectomy (MT) in basilar artery occlusion (BAO) for >10 years. Based on a single-center experience during the course of one decade, we present data on safety and efficacy of previous MT devices compared with modern stent retriever and suction thrombectomy. Eighty-one patients (29 ...
Ingole Pranav D PD Lecturer, Department of Oral and Maxillofacial Surgery, Vidya Shikshan Prasarak Mandal Dental College and Research Centre, Nagpur, Maharashtra, India. Electronic address: - - 2014
The aim of the present randomized study was to evaluate the efficacy of intermaxillary fixation screw (IMFS) versus eyelet interdental wiring for intermaxillary fixation (IMF) in minimally displaced mandibular fractures. A total of 50 patients with a minimally displaced mandibular fracture were enrolled, with 25 patients randomly selected for each ...
Duffett Lisa D LD aThrombosis Program, Division of Hematology, Department of Medicine, University of Ottawa bClinical Epidemiology Program, The Ottawa Hospital Research Institute, Ottawa, - - 2014
Data regarding inferior vena cava (IVC) filter use and complications are scarce. This study evaluates the safety and efficacy of IVC filters over a 4-year period at two adult tertiary care hospital sites. A retrospective observational study was conducted of consecutive admitted patients who underwent insertion of an IVC filter ...
Matsunaga Shigeo S Department of Neurosurgery, Yokohama Rosai - - 2014
The long-term outcomes of gamma knife surgery (GKS) in patients with posterior fossa arteriovenous malformations (AVMs) were retrospectively analyzed in 82 patients followed up for more than 5 years to evaluate the efficacy and safety. The median AVM volume at GKS was 0.95 cm(3). The prescribed dose to the AVM ...
Long Anhua A Department of Orthopedics, Chinese PLA General Hospital, Beijing, 100853, People's Republic of - - 2014
Thromboprophylaxis with rivaroxaban has proved effective and safe in patients undergoing hip and knee replacement surgery. As it is unclear whether it is also effective and safe in fracture patients, the aim of the present study was to evaluate the efficacy and safety of rivaroxaban in patients with lower limb ...
Jones Terry M - - 2014
Tinea cruris, a pruritic superficial fungal infection of the groin, is the second most common clinical presentation for dermatophytosis.<BR /> This phase 3 study evaluated the safety and efficacy of topical luliconazole cream 1% in patients with tinea cruris.<BR /> 483 patients were enrolled and 256 male and female patients ...
Martins Raphaël P RP CHU Rennes, Service de Cardiologie et Maladies Vasculaires, Rennes, F-35000, France; Université de Rennes 1, LTSI, Rennes, F-35000, France; INSERM, U1099, Rennes, F-35000, France; INSERM, CIC-IT 804, Rennes, F-35000, France. Electronic address: - - 2014
Compared with the first-generation Arctic Front (ARC-CB), the new Arctic Front Advance (ARC-Adv-CB) cryoballoon increases efficient balloon-tissue contact surface during freezing, which may increase phrenic nerve (PN) palsy (PNP) incidence. To evaluate the safety and efficacy of paroxysmal atrial fibrillation (AF) ablation with the ARC-Adv-CB, and the merits of a ...
Alió Jorge L - - 2014
To compare the efficacy and safety outcomes of bimanual microincision cataract surgery (MICS) versus 2.2-mm coaxial phacoemulsification assisted by Femtosecond LenSx (Alcon-LenSx Inc., Aliso Viejo, CA). This prospective, randomized, observational, comparative case series comprised 50 cataractous eyes of 50 patients receiving femtosecond laser refractive lens surgery followed by a bimanual ...
Alió Jorge L - - 2014
To compare the efficacy and safety outcomes of bimanual microincision cataract surgery (MICS) versus 2.2-mm coaxial phacoemulsification assisted by Femtosecond LenSx (Alcon-LenSx Inc., Aliso Viejo, CA). This prospective, randomized, observational, comparative case series comprised 50 cataractous eyes of 50 patients receiving femtosecond laser refractive lens surgery followed by a bimanual ...
Kasel Albert Markus AM Klinik für Kardiologie und Intensivmedizin, Klinikum Bogenhausen Munich, Germany ; Deutsches Herzzentrum, Technische Universität Munich, - - 2014
Few data is available comparing Edwards SAPIEN XT - SXT (Edwards Lifesciences, Irvine, California) with Medtronic CoreValve - CoV (Medtronic Inc., Minneapolis, Minnesota) in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement (TAVR). We selected consecutive patients undergoing transfemoral TAVR with SXT or CoV at our Institution. Main ...
Shamban Ava A ATS Clinical Research, Santa Monica, - - 2014
Due to advances in detection and treatment, approximately 70 percent of cancer patients are living more than five years after diagnosis. Research indicates that appearance worries are of great concern to cancer survivors impacting their quality of life. This is the first Phase IV investigator-initiated study to investigate the safety ...
Shah Sanjay S Senior Demonstrator, Department of Pharmacology, Government Medical College , Jammu and Kashmir, India - - 2014
To compare the safety and efficacy of Enoxaparin (EX) and Fondaparinux (FD) in patients with Unstable Coronary Artery Disease (UCAD). A prospective, open label, randomized comparative study was designed to study the comparative efficacy and safety of EX and FD in UCAD patients. Recovery, recurrence, major and minor bleeding and ...
Zhu Bin B Department of Critical Care Medicine, Third Affiliated Hospital of Soochow University, Changzhou, China - - 2014
Background The complexity of multiple-item criteria in acute respiratory distress syndrome (ARDS) often causes inconvenience for physicians in the management of patients with severe acute pancreatitis (SAP). We evaluated whether serum SP-A levels in the presence of diffuse alveolar damage (DAD) can be qualitatively assessed for diagnosis of SAP-induced ARDS. ...
Alosh Hassan H Department of Orthopaedic Surgery, Hospital of the University of Pennsylvania, Philadelphia, - - 2013
The number of patients requiring bilateral total knee arthroplasty (TKA) is expected to grow rapidly. While some trials have compared staged with simultaneous TKA, no literature characterizes the subset of staged TKA patients who cancel their second surgery. In this study, we report on the safety and utility of a ...
Wiebe Jens - - 2013
Objective: To evaluate the safety of percutaneous left atrial appendage (LAA) closure with the Amplatzer Cardiac Plug (ACP) in patients with non-valvular atrial fibrillation (AF) who are not eligible for oral anticoagulation with warfarin. Background: Anticoagulation is the treatment of choice for prevention of strokes in patients with AF, but ...
Vakil Kairav - - 2013
Background: The MitraClip® system is a newer percutaneous device that has shown promising results but data on its safety and efficacy in low and high surgical risk populations continues to evolve. We performed a systematic review of the published studies reporting the safety and efficacy of MitraClip® implantation for treatment ...
Knerr Meike - - 2013
Objective. The aim of this study was to evaluate the safety and efficacy of the GORE® Septal Occluder (GSO) at 1-, 6- and 12-month follow-up in patients with a clinical indication for patent foramen ovale (PFO) closure. Background. Limited data are available regarding the safety and efficacy of the GSO ...
Rizzoli Rene - - 2013
To investigate the efficacy and safety of oral fixed-dose combination strontium ranelate 2 g/vitamin D3 1,000 IU daily vs. strontium ranelate 2 g daily for correction of vitamin D insufficiency in osteoporosis. A 6-month international, randomized, double-blind, parallel-group, phase 3 study. 518 men and postmenopausal women aged ≥50 years with ...
Barahona-Guzmán Nayide - - 2013
To assess the feasibility and effectiveness of the International Nosocomial Infection Control Consortium (INICC) multidimensional hand hygiene (HH) approach in Colombia, and analyze predictors of poor HH compliance. An observational, prospective, interventional, before-and-after study was conducted from May 2003 through September 2010 in 10 intensive care units (ICUs) of six ...
Fritsch Gerhard - - 2013
Research suggests that the addition of dexmedetomidine to local anesthetics can prolong peripheral nerve blocks; however, clinical safety data are limited, and interscalene blocks have not been studied. The present study was designed to test the hypothesis that dexmedetomidine added to ropivacaine would safely enhance the duration of analgesia without ...
Fernandez Sierra M Amelia - - 2013
This study aims to estimate the incidence of adverse events (AEs) and avoidable AE in four hospital services before and after applying strategies for patient safety. Retrospective study of two cohorts (2006 and 2009). General Surgery, Internal Medicine, Intensive Care Unit and Oncology services. A sample of 365 patients (2006) ...
Ruff Christian T CT Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. Electronic address: - - 2014
Four new oral anticoagulants compare favourably with warfarin for stroke prevention in patients with atrial fibrillation; however, the balance between efficacy and safety in subgroups needs better definition. We aimed to assess the relative benefit of new oral anticoagulants in key subgroups, and the effects on important secondary outcomes. We ...
Selmon Matthew R - - 2013
Purpose : To evaluate the safety and effectiveness of the optical coherence tomography-guided Ocelot catheter to cross femoropopliteal chronic total occlusions (CTOs). Methods : The CONNECT II study was a prospective, multicenter, non-randomized single-arm study of the safety and effectiveness of the Ocelot catheter in CTO crossing. Key inclusion criteria ...
Kulkarni A G AG Department of Orthopaedics, Bombay Hospital and Medical Research Centre, Mumbai, - - 2013
A 48-year-old woman presented with severe bilateral leg pain, urinary incontinence, and paraparesis following vertebroplasty in another hospital 15 days earlier. Computed tomography and magnetic resonance imaging showed blocks of epidural and intradural cement from T12 to L1 with neurological compression. She underwent corpectomy of L1 and removal of extradural ...
Gültekin Salih Sinan SS Department of Nuclear Medicine, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, - - 2013
Most of the radiopharmaceuticals used in nuclear medicine are excreted via the urinary system. This study evaluated the importance of a reduction in bladder radioactivity for radiation safety. The study group of 135 patients underwent several organ scintigraphies [40/135; thyroid scintigraphy (TS), 30/135; whole body bone scintigraphy (WBS), 35/135; myocardial ...
Selig Christoph - - 2013
Predicting the neurological outcome after cardiopulmonary resuscitation (CPR) is extremely difficult. We tested the hypothesis whether monitoring of bispectral index (BIS) and suppression ratio (SR) could serve as an early prognostic indicator of neurological outcomes after CPR. Cerebral monitoring (BIS, SR) was started as soon as possible after initiation of ...
Naess H - - 2013
To compare short-term outcome and long-term mortality in old and younger patients with ischemic stroke. We hypothesized that short-term outcomes in patients ≥80 and <80 years with no neurological worsening are similar. The National Institute of Health Stroke Scale (NIHSS) was used to assess stroke severity. Short-term outcome was determined by ...
Youssof Sarah - - 2013
Introduction: Despite multiple studies reporting marked benefit of botulinum toxin (BTX) for treatment of cricopharyngeal dysphagia, little is known about its safety for this indication. We examined the safety of cricopharyngeal BTX for dysphagia in oculopharyngeal muscular dystrophy (OPMD). Methods: We reviewed records of patients with OPMD who received cricopharyngeal ...
Mao Wei - - 2013
Screening esophagogastroduodenoscopy (SEGD) is recommended in liver cirrhotic patients while endoscopic variceal ligation (EVL) is used as secondary prophylaxis for esophageal varices. Although sedation is commonly used in gastrointestinal endoscopy, the safety of sedation is unclear for SEGD and EVL in cirrhotic patients. This study was aimed to investigate the ...
Hummel John - - 2013
Persistent and long-standing persistent atrial fibrillation (AF) often requires extensive and/or repeat radiofrequency ablation (RFA) procedures. The Tailored Treatment of Persistent Atrial Fibrillation (TTOP-AF) study assessed the effectiveness and safety of the Phased RF system in a randomized, controlled comparison of medical therapy against phased RFA for management of persistent ...
Mazzoleni S - - 2013
The aim was to compare the efficacy of the electric versus the manual toothbrush in terms of the oral hygiene achieved by patients wearing rapid palatal expanders (RPEs). Forty patients were randomly divided into two groups; one equipped with a manual toothbrush (Group A), the other with an electric toothbrush ...
Baram Ilan - - 2013
To evaluate the initial safety and effectiveness of the intrauterine ball (IUB), a copper intrauterine device that, upon insertion in the uterus, takes a three-dimensional spherical form. Fifteen women were followed for 1 year, with follow-up visits at 1, 3, 6, 9 and 12 months. The physician reported that all ...
Wang Bingsong - - 2013
To evaluate the efficacy and safety of intracameral triamcinolone acetonide in phacotrabeculectomy. Beijing Shijitan Hospital, Capital University of Medical Sciences, Beijing, China. Prospective randomized controlled trial. Patients having combined trabeculectomy and cataract surgery were enrolled from March 2010 through January 2012. The patients were randomly divided into 4 groups. At ...
Bazan Hernan A - - 2013
Increasing evidence supports that urgent carotid endarterectomy (CEA), defined as CEA during the index hospitalization, may be undertaken in select patients with acute carotid-related neurological symptoms to prevent recurrent ischemic events. We aimed to determine the effect of a stroke/vascular neurology service on the volume of urgent CEAs performed and ...
Zhou Jian-Hui - - 2013
A multi-center large scale study is needed to confirm the efficacy and safety of domestic peritoneal dialysis (PD) solutions. Some researchers believe that 6 L/d is enough for adequate dialysis, but there is no multi-center prospective study on Chinese population to confirm this. In this study, we evaluated the efficacy ...
Corriere Matthew A - - 2013
Carotid revascularization, including carotid endarterectomy (CEA) and carotid angioplasty and stenting (CAS), is performed for stroke risk reduction but may also impact cognitive function. Cognitive outcomes observed following carotid revascularization have been inconsistent, and mechanistic relationships with procedural factors are poorly understood. To further explore associations between carotid revascularization and ...
Boulanger Henri - - 2013
<title>ABSTRACT</title> <bold><italic>Purpose:</italic></bold> Our aim was to evaluate the safety and effectiveness of the IRIS® bandage (Nephrokit®) on post-puncture bleeding compared to conventional manual compression. <bold><italic>Methods:</italic></bold> Sixty-four patients, hemodialyzed with an arteriovenous fistula, were enrolled in a 3-week prospective study. Conventional manual compression was used during the first week, the IRIS® ...
Liew A - - 2013
Extended-duration thromboprophylaxis with low molecular weight heparin (LMWH) reduces the frequency of symptomatic venous thromboembolism (VTE) among patients undergoing total hip or knee arthroplasty (1). Recent trials have evaluated the efficacy and safety of the new oral anticoagulants (NOACs), dabigatran etexilate, rivaroxaban and apixaban, for VTE prevention in patients undergoing ...
Lee Tae Rim - - 2013
Several methods have been proposed to evaluate neurological outcome in out-of-hospital cardiac arrest (OHCA) patients. Blood lactate has been recognized as a reliable prognostic marker for trauma, sepsis, or cardiac arrest. The objective of this study was to examine the association between initial lactate level or lactate clearance and neurologic ...
Bae Dong Sik DS Department of Surgery, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, - - 2013
A number of researchers have suggested the use of sodium hyaluronate carboxymethyl cellulose (HA-CMC) membrane for preventing postoperative adhesion. This study evaluated the antiadhesive effect and safety of HA-CMC membrane in thyroidectomy for papillary thyroid cancer. One hundred sixty-two patients who underwent thyroidectomy were prospectively randomized. In the study group ...
Volovat Constantin C Centrul de Oncologie Medicala, Iasi, - - 2013
Recombinant granulocyte colony-stimulating factors (G-CSFs) reduce the incidence and duration of chemotherapy-induced neutropenia and febrile neutropenia when given as adjunct therapy to patients receiving myelosuppressive chemotherapy. Balugrastim is a long-acting G-CSF composed of a genetic fusion between recombinant human serum albumin and G-CSF. We compared the efficacy and safety of ...
Palomba Stefano - - 2013
To compare single-incision mini-slings (SIMS) and retropubic tension free vaginal tape (r-TVT) in terms of the long-term efficacy and safety for the treatment of female stress (SUI) or mixed urinary incontinence (MUI). Prospective multicenter cohort trial (registration number NCT00751088). Canadian Task Force - II SETTINGS: Department of Obstetrics and Gynecology, ...
Lin David M - - 2013
The use of erythropoietin (EPO) and intravenous (IV) iron as bloodless therapeutic modalities is being explored in the current era of restrictive transfusion strategies and perioperative blood management. It is unclear, however, whether the evidence in the literature supports their safety and efficacy in reducing perioperative red cell transfusions. Adhering ...
Gempt Jens - - 2013
Object Brain metastases occur in 10% to 40% of patients harboring cancer. In cases of neurosurgical metastasis resection, all postoperative neurological deterioration should be avoided. Reasons for postoperative deficits can be direct tissue damage due to resection, hemorrhage, venous congestive infarcts, or arterial ischemic events leading to tissue infarction. The ...
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