Search Results
Results 1 - 50 of 1640
1 2 3 4 5 6 7 8 9 10 >
Sugaya N N Department of Epidemiology and Public Health, Graduate School of Medicine, Yokohama City University, Japan Addictive Substance Project, Tokyo Metropolitan Institute of Medical - - 2014
The present prospective randomized controlled study investigated the effect of ifenprodil, a G-protein-activated inwardly rectifying potassium (GIRK) channel inhibitor, on alcohol reuse in patients with alcohol dependence. The participants were 50 outpatients with alcohol dependence who were assigned to two groups: ifenprodil group (administered ifenprodil for 3 months) and control ...
Kim Dong Wook DW *Department of Neurology, Konkuk University School of Medicine; and †Department of Neurology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South - - 2014
Zonisamide (ZNS) is an antiepileptic drug with a broad spectrum of action mechanisms. Although ZNS is usually indicated for the adjunctive treatment of partial seizures in Western countries, it has long been used for partial and generalized seizures as monotherapy or adjunctive treatment in South Korea and Japan. The present ...
Gabriel Wendy M WM The University of Tennessee Medical Center Knoxville, TN, USA The University of Tennessee Health Science Center, College of Pharmacy, Knoxville, TN, - - 2014
Much debate exists on the optimal medication for posttraumatic seizure prophylaxis after traumatic brain injury (TBI). There is some evidence that levetiracetam (LEV) could be neuroprotective and provide long-term benefits in this patient population. The primary objective was to compare the Glasgow Outcome Scale-Extended (GOS-E) 6 months or more after ...
Gallo A S AS Minimally Invasive Surgery Department, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA, - - 2014
It has been published that patients who underwent gastric bypass surgery have impaired alcohol metabolism, predisposing them to higher rates of intoxication and DUI arrests. Yet the impact of laparoscopic sleeve gastrectomy (LSG) on alcohol metabolism and in particular the long-term effects are still unclear. We hypothesized that LSG does ...
Kelleher Maureen E ME William R. Pritchard Veterinary Medical Teaching Hospital, University of California-Davis, Davis, - - 2014
To determine if application of silver sodium zirconium phosphate polyurethane semi-occlusive foam (SPF) dressing would improve measures of wound healing and decrease bacterial contamination compared with a non-adherent, absorbent dressing applied to wounds created on the distal aspect of the equine limb. Controlled randomized experimental study. Adult Quarter Horse and ...
Raz Guy G 28 Truscott Street, North Ryde, NSW 2113, Australia. E-mail address: - - 2014
Osteochondral defects of the knee in young, active patients represent a challenge to the orthopaedic surgeon. Our study examined long-term outcomes of the use of fresh allograft for posttraumatic osteochondral and osteochondritis dissecans defects in the distal aspect of the femur.METHODS: We reviewed the cases of sixty-three patients who underwent ...
Inoue Manabu M From the Department of Neurology, Stanford Stroke Center, Stanford University Medical Center, CA (M.I., J.-M.O., M. Mlynash); Department of Neurology, Purpan University Hospital, Toulouse, France (J.-M.O., J.-F.A.); Department of Neurology and Stroke Centre, Bichat University Hospital, APHP, Paris, France (E.M., P.A., M. Mazighi); INSERM U-1148, Laboratory of Vascular Translational Science and Paris-Diderot University, Paris, France (J.L., E.M., P.A., M. Mazighi); and Department of Biostatistics, EA2694, UDSL, Université Lille Nord de France, CHU Lille, France - - 2014
In acute ischemic stroke patients treated by intravenous thrombolysis, a diffusion-weighted imaging (DWI) Alberta Stroke Program Early Computed Tomography Score (ASPECTS) is an independent factor of functional outcomes. Our aim was to assess the impact of pretreatment DWI-ASPECTS on outcomes after endovascular therapy, with a specific emphasis on recanalization. We ...
Yoo Albert J AJ From Massachusetts General Hospital, Boston, MA (A.J.Y., Z.A.C., O.A.B., R.G.G.); Medical College of Wisconsin, Milwaukee, WI (O.O.Z.); University of Calgary, Calgary, AB, Canada (M.G., A.M.D., B.K.M.); Penumbra Inc, Alameda, CA (E.M., D.U., H.B., S.P.S., - - 2014
The efficacy of intra-arterial treatment remains uncertain. Because most centers performing IAT use noncontrast CT (NCCT) imaging, it is critical to understand the impact of NCCT findings on treatment outcomes. This study aimed to compare functional independence and safety among patients undergoing intra-arterial treatment stratified by the extent of ischemic ...
Maingard Julian J Melbourne Brain Centre, Royal Melbourne Hospital, Parkville, VIC, - - 2014
Intra-arterial (IA) therapy for stroke is an increasingly utilised management approach for acute ischaemic stroke. We aimed to correlate radiological characteristics and recanalisation success with radiological and functional outcomes at 90days in patients treated with IA therapy. This was a single centre, retrospective study investigating the correlation between pre-procedural Computed ...
Gu Jia-Xiang JX Hand and Foot Surgery Department, The People Hospital of Subei, Affiliated Clinical College of Yangzhou University, No. 98, The West Nangtong Road, Yangzhou, 225001, Jiangsu, People's Republic of - - 2014
This study illustrates aesthetic and sensory reconstruction of finger pulp defects with free toe flaps from the lateral aspect of the great toe or the medial aspect of the second toe. Between August 2007 and July 2010, free toe flaps were harvested and used for 21 fingers of 21 patients. ...
Huang D H DH Department of Neurology, The First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, - - 2014
This study aimed to investigate the prevalence and treatment gaps of epilepsy, as well as the clinical effects, drug safety, and retention rates of sodium valproate (VPA) for treating epilepsy. Physicians received supervised training to use the survey form recommended by the Chinese Association Against Epilepsy while screening for suspected ...
Jaimes Rafael R 3rd The George Washington University, 2300 I St NW Ross Hall Room 456, Washington D.C 20037, - - 2014
Epidural lipomatosis (EL) is an increase of adipose tissue, normally occurring in the epidural space, sufficient to distort the thecal sac and compress neural elements. There is a lack of knowledge of risk factors, impact on patient's symptoms, and its possible association with epidural steroid injections. History, physical examination, patient ...
Favacho Bernard Costa - - 2013
Gastric neoplasia is a heterogeneous and multifactorial disease and its incidence and mortality vary widely based on geographic location. Approximately 60% of the diagnoses of patients from occidental countries were made on the stages III and IV. The best treatment still is to realize a surgical procedure. Identify the epidemiological ...
Hwang Hyung Sik HS Department of Neurosurgery, Dongtan Sacred Heart Hospital, College of Medicine, Hallym University, Hwaseong, - - 2013
The objective of this study was to investigate changes in the posterior cranial fossa in patients with symptomatic Chiari malformation type I (CMI) compared to a control group. We retrospectively reviewed clinical and radiological data from 12 symptomatic patients with CMI and 24 healthy control subjects. The structures of the ...
Phuttharak Warinthorn - - 2013
To determine whether the Alberta Stroke Program Early CT Scores (ASPECTS) can predict posttreatment functional outcomes in hyperacute stroke patients who receive recombinant tissue-type plasminogen activator (rt-PA) treatment within 4.5 h. We studied 162 patients treated with rt-PA within 4.5 h of clinical onset. Of those, 29 patients (17.90 %) received rt-PA treatment ...
Giannini Sandro - - 2013
Autologous chondrocyte implantation (ACI) is an established procedure in the ankle providing satisfactory results. The development of a completely arthroscopic ACI procedure in the ankle joint made the technique easier and reduced the morbidity. The purpose of this investigation was to report the clinical results of a series of patients ...
McDonald Lcdr Lucas S - - 2013
PROXIMAL ASPECT OF BICEPS  ➤ Tenodesis of the long head of the biceps may offer improved cosmesis, improved strength, and diminished activity-related pain compared with tenotomy, although comparative studies have shown similar outcomes in some patient populations. DISTAL ASPECT OF BICEPS  ➤ Operative treatment of both partial and complete distal ...
Strbian Daniel D Department of Neurology, University of Helsinki, Helsinki, Finland. - - 2013
To evaluate the impact of extensive baseline ischemic changes on functional outcome after thrombolysis of basilar artery occlusion (BAO), and to study the effect of time to treatment in the absence of such findings. We prospectively evaluated 184 consecutive patients with angiography-proven BAO. The majority of patients received intravenous alteplase ...
Garofolo Stephen - - 2013
OBJECTIVE: To (1) evaluate the normal extraosseous blood supply of the cranial aspect of the canine radius and (2) to compare the effects of minimally invasive (MIPO) and open plating technique on its preservation. STUDY DESIGN: Experimental cadaveric study. SAMPLE POPULATION: Adult canine thoracic limbs (n = 36) obtained from cadavers weighing ...
Vissers M M - - 2013
Our previous study showed that 6 months after total hip arthroplasty (THA) or total knee arthroplasty (TKA), patients reported having less difficulty with daily activities, showed better functional capacity, and performed activities in their natural environment faster compared to preoperatively. However, their actual daily activity level was not significantly improved. ...
Ohrndorf S - - 2013
Objective. The main objective of this study was to evaluate the 7-joint ultrasound (US7) score by detailed joint region analysis of an arthritis patient cohort. Methods. The US7 score examines the clinically most affected wrist, MCP and PIP II, III, MTP II, and V joints for synovitis, tenosynovitis/paratenonitis, and erosions. ...
Gyebre Y M C YM Department of Otolaryngology (ENT) and Cervico-Facial Surgery (CFS), "Yalgado Ouedraogo" University Hospital (CHU-YO), 03 BP 7022, Ouagadougou 03, Burkina Faso ; Faculty of Health Sciences (FHS), 03 BP 7021, Ouagadougou 03, Burkina - - 2013
Objectives. The aim of this study was to analyze the epidemiological and clinical aspects of chronic otitis media and its therapeutic processes in our context. Patients and Methods. In a prospective study over a period of 1 year (March 2009-February 2010), 79 patients with chronic otitis media have been cared ...
Horhoianu I A - - 2012
OBJECTIVE AND RATIONALE: The purpose of this study is to evaluate the degree of fibroid shrinkage which well correlates with symptom regression, and thus to assess the effectiveness of the procedure. 31 patients were included in the trial after selection. All the patients were thoroughly evaluated before embolization, the following ...
Aoki Junya - - 2012
BACKGROUND AND PURPOSE: In patients with middle cerebral artery trunk occlusion we investigated whether the diffusion-weighted imaging- the Alberta Stroke Program Early Computed Tomography Score (DWI-ASPECTS) predicts short-term neurological recovery after intravenous recombinant tissue plasminogen activator administration, and investigated how DWI-ASPECTS relates to clinical outcome. METHODS: Dramatic recovery was defined ...
Lee Jun Seok - - 2012
Fungal ball in paranasal sinus was reported to be rare, but these days we have encountered numerous cases. We retrospectively analyzed the data of 4,485 patients with chronic rhinosinusitis (CRS) who underwent sinus surgery from 1999 to 2010. Patients were categorized into group A (patients from 1999 to 2004) and ...
Sasaki Hiroyoshi - - 2012
ABSTRACT: We evaluated the effects of presurgical nasoalveolar molding (NAM) with an orthopedic appliance and compared them with a passive orthopedic method (Hotz plate, HP), focusing on the naris morphology and width of the alveolar and palate cleft gap. The subjects were 28 unilateral complete cleft lip and palate patients ...
Costalat V - - 2012
BACKGROUND AND AIMS: New thrombectomy devices allow successful and rapid recanalization in acute ischemic stroke. Nevertheless prognostics factors need to be systematically analyzed in the context of these new therapeutic strategies. The aim of this study was to analyze prognostic factors related to clinical outcome following Solitaire FR thrombectomy in ...
Furman Michael B - - 2012
Objectives.  We identify the contrast volumes needed to reach specific landmarks during S1 transforaminal epidural injections (S1-TFEIs). Design.  Prospective, nonrandomized, observational human study. Setting.  Academic/private pain management practice. Subjects.  Forty-two patients undergoing S1-TFEIs were investigated. Thirty-seven patients were included in this study. Interventions.  S1-TFEIs were performed using contrast-enhanced fluoroscopic visualization. ...
Markun Leslie C - - 2012
: Treatment with deep brain stimulation (DBS) of the globus pallidus internus in children with DYT1 primary torsion dystonia is highly effective; however, individual response to stimulation is variable, and a greater understanding of predictors of long-term outcome is needed. : To report the long-term outcomes of subjects with young-onset ...
Di Napoli Mario - - 2012
OBJECTIVES:We examined the C-reactive protein (CRP) response after spontaneous intracerebral hemorrhage (sICH) and its relationship to outcome. We additionally characterized early brain localization of CRP. METHODS:In this prospective, multicenter, international, collaborative, longitudinal study with cross-sectional immunohistochemical analysis of brain tissue, 223 patients (M/F: 132/91) were recruited during the 2010 calendar ...
Mukesh M - - 2012
A study of interobserver variation in the segmentation of the post-operative clinical target volume (CTV) and organs at risk (OARs) for parotid tumours was undertaken. The segmentation exercise was performed as a baseline, and repeated after 3 months using a segmentation protocol to assess whether CTV conformity improved. Four head ...
Andropoulos Dean B DB Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA. - - 2013
In this study we report magnetic resonance imaging (MRI) brain injury and 12-month neurodevelopmental outcomes when regional cerebral perfusion (RCP) is used for neonatal aortic arch reconstruction. Fifty-seven neonates receiving RCP during aortic arch reconstruction were enrolled in a prospective outcome study. RCP flows were determined by near-infrared spectroscopy and ...
Erb Jessica L - - 2012
Irreversible brain damage and death are common outcomes after cardiac arrest, even when resuscitation is initially successful. Chances for both survival and a good neurologic outcome are improved when mild hypothermia is induced shortly after reperfusion. Unfortunately, this treatment is often omitted from advanced cardiac life support protocols. The authors ...
Wu Hemmings - - 2012
OBJECTIVE: Anorexia nervosa (AN) is a complex and severe, sometimes life-threatening psychiatric disorder with high relapse rates under standard treatment. After decades of brain lesioning procedure offered as the last resort, deep brain stimulation (DBS) came under investigation in the last few years as a treatment option for severe and ...
Franzini Angelo - - 2012
OBJECTIVE: To describe our Institutional experience with Deep Brain Stimulation ( DBS) employed for treatment of aggressive and disruptive behaviour refractory to conservative treatments METHODS: With stereotactic methodology and under general anaesthesia, 7 patients ( from 2002 to 2010) were submitted to DBS of posterior hypothalamic ( pHyp) region, bilaterally, ...
Vaneckova M - - 2012
Aim: To determine whether corpus callosum atrophy predicts future clinical deterioration in multiple sclerosis. Methods: In 39 multiple sclerosis patients the area of corpus callosum in the sagittal plane, T(2) and T(1) lesion volumes, brain parenchymal fraction and brain atrophy were determined at baseline and 1 year after treatment initiation. ...
Eriksson Evert A - - 2012
Utilization of brain tissue oxygenation (pBtO(2)) is an important but controversial variable in the treatment of traumatic brain injury. We hypothesize that pBtO(2) values over the first 72 hours of monitoring are predictive of mortality. Consecutive, adult patients with severe traumatic brain injury and pBtO(2) monitors were retrospectively identified. Time-indexed ...
Lannes Marcelo - - 2012
INTRODUCTION: For the treatment of cerebral vasospasm, current therapies have focused on increasing blood flow through blood pressure augmentation, hypervolemia, the use of intra-arterial vasodilators, and angioplasty of proximal cerebral vessels. Through a large case series, we present our experience of treating cerebral vasospasm with a protocol based on maintenance ...
Han Jung Ho - - 2012
PURPOSE: To identify the effect of brain atrophy on the development of symptomatic communicating hydrocephalus (SCHCP) after stereotactic radiosurgery (SRS) for sporadic unilateral vestibular schwannomas (VS). METHODS AND MATERIALS: A total of 444 patients with VS were treated with SRS as a primary treatment. One hundred eighty-one patients (40.8%) were ...
Zhao Yongqing - - 2012
OBJECTIVE: To explore the incidence, types of onset, and risk factors of posttraumatic epilepsy (PTE). METHODS: This is a retrospective follow-up study of patients discharged from the Affiliated Hospital of the Medical College of the Chinese People's Armed Police Forces between September 2004 and September 2008 with a diagnosis of ...
Magraner M - - 2012
OBJECTIVE: To assess the evolution of brain atrophy and its relationship with inflammatory activity in RRMS patients treated with natalizumab. METHODS: Eighteen RRMS patients were prospectively followed up for 18 months after starting natalizumab therapy. Patients were monitored monthly and assessed for signs of relapses, adverse events or disability increase. ...
Sämann P G - - 2012
BACKGROUND AND PURPOSE:MRI markers of neuroaxonal damage in MS have emerged as critical long-term predictors of MS-related disability. Here we investigated the potential of whole-brain diffusivity and brain volume for the prediction of cross-sectional disability and short- to medium-term clinical evolution.MATERIALS AND METHODS:In this multimodal prospective longitudinal MRI study of ...
Talving Peep - - 2012
To validate previous findings of the effects of erythropoiesis-stimulating agent (ESA) administration following severe traumatic brain injury. Prospective observational study of all patients with severe traumatic brain injury admitted to the surgical intensive care unit (SICU) at our institution from January 1, 2009, to December 31, 2010 (head Abbreviated Injury ...
Parkhutik Vera - - 2012
BACKGROUND AND PURPOSE: The long-term benefit of radiosurgery of brain arteriovenous malformations (AVM), especially nonhemorrhagic cases, is controversial. We calculated hemorrhage rates pre- and posttreatment and analyzed the risk factors for bleeding based on cases followed at our site. METHODS: One hundred eight patients, age 36±17 years, 56 men. The ...
Tanoue Koji - - 2012
Aim:  The aim of this study was to evaluate the value of early radiological investigations in predicting the long-term neurodevelopmental outcome of patients with inflicted traumatic brain injury (ITBI). Methods:  In 28 patients with ITBI, radiological investigations were performed during the acute phase of injury (0-3 days) and during the ...
Favilla Christopher G - - 2012
A major concern regarding ventralis intermedius nucleus deep brain stimulation for essential tremor has been the loss of surgical efficacy over time in a minority of patients. Some experts have ascribed the worsening tremor to tolerance, while other evidence has suggested that disease progression may play a role. Suboptimal lead ...
Greiner Hansel M - - 2012
To determine vigabatrin's effectiveness and the prevalence of symptomatic visual impairment (i.e., impairment affecting the ability to perform everyday activities) associated with its therapy in pediatric epilepsy, we retrospectively reviewed medical records of 156 patients receiving vigabatrin at Cincinnati Children's Medical Center from 1998-2010. In addition to demographics and vigabatrin ...
Oliveira Carol - - 2012
OBJECTIVE:Patients with pediatric intestinal failure (IF) depend on parenteral nutrition for growth and survival, but are at risk for complications, such as catheter-related bloodstream infections (CRBSIs). CRBSI prevention is crucial, as sepsis is an important cause of IF-associated liver disease and mortality. We aim to estimate the pooled effectiveness and ...
Montes Felix R - - 2012
Antifibrinolytic agents are used during cardiac surgery to minimize bleeding and reduce exposure to blood products. Several reports suggest that tranexamic acid (TA) can induce seizure activity in the postoperative period. To examine factors associated with postoperative seizures in patients undergoing cardiac surgery who received TA. University-affiliated hospital. Case-control study. ...
Alkan Alpay - - 2012
To search brain perfusion MRI (pMRI) changes in Behcet's disease (BD) with or without neurological involvement. The pMRI were performed in 34 patients with BD and 16 healthy controls. Based on neurologic examination and post-contrast MRI, 12 patients were classified as Neuro-Behcet (group 1, NBD) and 22 patients as BD ...
1 2 3 4 5 6 7 8 9 10 >