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Schwyzer Lucia L Department of Neurosurgery, Kantonsspital Aarau, Aarau, - - 2015
To evaluate the subjective outcome and quality of life (QoL) of patients who suffered from aneurysmal subarachnoid hemorrhage and underwent endovascular coiling or microsurgical clipping in a single center. For this retrospective single-center study, we included patients who underwent aneurysm occlusion at the Cantonal Hospital of Aarau between January 2000 ...
Kimura Hidehito H Department of Neurosurgery, Kobe University Graduate School of Medicine, 7-5-1, Kusuniki-cho, Chuo-ku, Kobe, 650-0017, Japan, - - 2015
In order to prevent cerebral vasospasm (VS) following aneurysmal subarachnoid hemorrhage (SAH), we introduced combined enteral nutrition (EN) and parenteral nutrition (PN) with oral cilostazol administration to the postoperative patient after SAH and investigated the effect on VS. After aneurysmal SAH, 130 postoperative patients were enrolled in this study between ...
Colognato R R GeXNano srl, Gerenzano, Varese, Italy - - - 2014
The aim of this study was to develop a pharmacogenetic- (PGx) driven approach for a controlled ovarian hyperstimulation (COH) treatment protocol used for in vitro fertilization procedures. The enrolled patients were genotyped for a single nucleotide polymorphism (SNP) N680S, within the FSHR. Seventy-eight women, who had previously received at least ...
Abrisqueta J J Department of General Surgery, Colorectal Unit, Virgen de la Arrixaca University Clinical Hospital, University of Murcia, Murcia, - - 2014
Postoperative ileus is the most common complication after ileostomy closure with an increase in morbidity, hospital stay, and health care costs. The aim of this study is to assess the utility of a new technique for reducing postoperative ileus after protective ileostomy closure. This is a prospective randomized study registered ...
Whittaker Amy A From the *Sydney Children's Hospital; and †Prince of Wales Hospitals, Randwick; and ‡University of New South Wales, Sydney, New South Wales, - - 2014
It is thought that the function of a damaged kidney will deteriorate further with time because of impaired maturation and compensatory hyperfiltration. The aim of this study was to determine changes in relative renal function (RRF) over time in children with vesicoureteric reflux (VUR) and/or urinary tract infection (UTI) where ...
van Loon Maarten C MC *Department of Otolaryngology-Head and Neck Surgery; †The EMGO Institute for Health and Care Research; and ‡Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The - - 2014
To evaluate the effect of stapedotomy in cochlear implant candidates with far-advanced otosclerosis (FAO). Systematic review of literature and meta-analysis. PubMed, EMBASE, and Cochrane databases were searched for "stapedotomy" and "far-advanced otosclerosis" and their synonyms. The search was carried out on November 28, 2013; no language restrictions were applied. The ...
Lin Tsan-Shiun TS From the Department of Plastic and Reconstructive Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, - - 2014
Venous insufficiency after microsurgical replantation/revascularization remained to be a vexing problem for finger failure, despite the level of amputation. Other than redo the venous anastomosis, alternative methods such as subdermal pocket procedure (SDP) can be used. The aim of this study was to incorporate SDP immediately at the time of ...
Rish Adam A Laserase, Sydney, NSW, - - 2014
A review of 242 facial treatments, in 86 different patients, with polyacrylamide gel (PAAG) was carried out by the author between 2003 and 2013. To evaluate by retrospective study the long-term outcomes of PAAG filling for facial contouring. To quantify adverse events and patient comfort in prior mixing 0.3 mL of ...
Wodack Karin H KH 1Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. 2Department of General, Visceral and Thoracic Surgery, Center of Surgical Sciences, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. 3Laboratory of Pathology, Lübeck, - - 2014
In severe acute pancreatitis, the administration of fluids in the presence of positive fluid responsiveness is associated with better outcome when compared to guiding therapy on central venous pressure. We compared the effects of such consequent maximization of stroke volume index with a regime using individual values of stroke volume ...
Maria Rosario R 1Takeda Pharmaceuticals International Company, Cambridge, Massachusetts, 2Takeda Pharmaceuticals International Company, London, United Kingdom, 3Millennium Pharmaceuticals, Inc., Cambridge, Massachusetts, 4Metrum Research Group LLC, Tariffville, Connecticut, 5Millennium Pharmaceuticals, Inc., a Takeda Company, Cambridge, Massachusetts, 6University of California San Diego and UC San Diego Health System, La Jolla, - - 2014
A relationship between the pharmacokinetics (PK) of tumor necrosis factor antagonists and mucosal healing in patients with ulcerative colitis (UC) or Crohn's disease was recently reported. This analysis examines the relationship between the PK of vedolizumab (VDZ), an α4β7 integrin antagonist, and endoscopic outcomes in patients with UC using population ...
Thomas Walters W 1Hospital for Sick Children, Toronto, Canada, 2Children's Hospital of Eastern Ontario IBD Centre, University of Ottawa, Ottawa, Canada, 3Cincinnati Children's Hospital, Cincinnati, - - 2014
Linear growth impairment is a well recognized feature of Crohn's Disease (CD), although defining it is challenging. Its presence at diagnosis can be indicative of the duration of unrecognized disease, whilst patterns post-diagnosis are reflective of treatment and treatment efficacy. Over the past decade, the awareness of IBD in the ...
Bakker Olaf J OJ The authors' affiliations are listed in the - - 2014
Background Early enteral feeding through a nasoenteric feeding tube is often used in patients with severe acute pancreatitis to prevent gut-derived infections, but evidence to support this strategy is limited. We conducted a multicenter, randomized trial comparing early nasoenteric tube feeding with an oral diet at 72 hours after presentation ...
Schulz-Schüpke Stefanie S Deutsches Herzzentrum München, Technische Universität, Munich, Germany2DZHK, Partner Site Munich Heart Alliance, Munich, - - 2014
The role of vascular closure devices (VCD) for the achievement of hemostasis in patients undergoing transfemoral coronary angiography remains controversial. To compare outcomes with the use of 2 hemostasis strategies after diagnostic coronary angiography performed via transfemoral access-a VCD-based strategy with 2 types of devices, an intravascular device and an ...
Park Se Woo SW Department of Internal Medicine, Institute of Gastroenterology, Hallym University College of Medicine, Seoul, - - 2014
Background and study aims: Rectal nonsteroidal anti-inflammatory drugs have been shown to reduce the incidence of postendoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP). The aim of this study was to determine whether intramuscular diclofenac reduces the risk of PEP. Patients and methods: Patients who underwent ERCP were randomized to receive either ...
Swinkels B M BM Department of Cardiology, St. Antonius Hospital, PO Box 2500, 3435, CM, Nieuwegein, the Netherlands, - - 2014
Although younger patients are supposed to be less susceptible to bleeding complications of mechanical aortic valve replacement (mAVR) than older patients, there is a relative paucity of data on this subject. Therefore, it remains uncertain whether younger patients are really at a lower risk of these complications than older patients. ...
Heesakkers Nicole N Department of Orthopaedic Surgery, Radboud University Medical Centre, Nijmegen, The Netherlands, - - 2014
The purpose of this study is predicting the clinical and radiological long-term outcome and identifying prognostic factors of Legg-Calvé-Perthes disease (LCPD) in Catterall 2 and 3 hips. Sixty hips (59 patients) were diagnosed with LCPD between 1959 to 1974 and were followed prospectively. Forty-two of these 60 hips were classified ...
Weinberg L L Consultant anesthetist, Department of Anesthesia, Austin Hospital, Principal Fellow, Department of Surgery, and Perioperative and Pain Medicine Unit, Melbourne Medical School, The University Melbourne, Melbourne, Victoria, Australia - - - 2014
The acid--base, biochemical and hematological effects of crystalloid solutions have not been comprehensively evaluated in patients with liver resection. Design: Multicenter, prospective, double--blind randomized controlled trial investigating the biochemical effects of Hartmann's solution (HS) or Plasmalyte--148 (PL) in 60 patients undergoing major liver resection. Primary outcome: Base Excess immediately after ...
Scheyer M M Department of General Surgery, State Hospital, 6700, Bludenz, Vorarlberg, - - 2014
Rectoanal repair (RAR), which combines doppler-guided hemorrhoidal artery ligation (HAL) and mucopexy via lifting of the hemorrhoidal prolapse, offers a minimally invasive alternative to conventional hemorrhoidectomy. Patients with grade II hemorrhoids were treated with HAL, and patients with grade III and IV hemorrhoids were treated with the RAR procedure by ...
Lee Todd C - - 2014
Antibiotic use is an important quality improvement target. Nearly 50% of antibiotic use is unnecessary or inappropriate. To combat overuse, the Centers for Disease Control and Prevention (CDC) proposed "time-outs" to reevaluate antibiotics. To optimize antibiotic use through trainee-led time-outs. Before-after study. Internal medicine (2 units, 46 beds) at a ...
Choi In Ah - - 2014
Pelubiprofen is a prodrug of 2-arylpropionic acid with relatively selective effects on cyclooxygenase-2 activity. The aim of this study was to compare the efficacy and safety profiles of pelubiprofen with those of celecoxib in patients with rheumatoid arthritis. This was a 6-week, multicenter, randomized, double-blind, double-dummy, parallel-group, phase III, non-inferiority ...
Yokoyama Kunio K Department of Neurosurgery, Takeda General Hospital, 28-1, Ishidamoriminami-machi, Fushimi, Kyoto, Kyoto, 601-1495, Japan, - - 2014
The influence of vertebral cement augmentation on spinal sagittal balance is unknown. The present study aimed to analyze the changes in total spinal alignment after Kyphoplasty in VCF patients. The study involved 21 VCF patients who underwent Kyphoplasty. In all patients, lateral radiographs of the entire spine were taken preoperatively ...
Park Jaechan J Departments of Neurosurgery - - 2014
OBJECT While the incidence of a recurrent hemorrhage is highest within 24 hours of subarachnoid hemorrhage (SAH) and increases with the severity of the clinical grade, a recurrent hemorrhage can occur anytime after the initial SAH in patients with both good and poor clinical grades. Therefore, the authors adopted a ...
Dhakal Laxmi P LP Department of Critical Care, Mayo Clinic, Jacksonville, FL, - - 2014
Headache after aneurysmal subarachnoid hemorrhage (SAH) is very common and is often described as the "worst headache imaginable." SAH-associated headache can persist for days to weeks and is traditionally treated with narcotics. However, narcotics can have significant adverse effects. We hypothesize that gabapentin (GBP), a non-narcotic neuropathic pain medication, would ...
Chan Noel C NC Thrombosis and Atherosclerosis Research Institute, Hamilton, Canada, - - 2014
In the last decade, major advances in venous thromboembolism (VTE) prophylaxis in orthopaedic surgery have included the development of new anticoagulants that are poised to replace low molecular weight heparins (LMWHs) and improvements in operative and perioperative care that have likely led to a decline in the rates of symptomatic ...
Elman Monica - - 2014
Abstract INTRODUCTION: Since the introduction of fractional technology, various systems were launched to the market. The first generation of fractional RF systems created epidermal ablation with coagulative/necrosis of the dermis with sufficient clinical outcomes, but with some limitations. The aim of this study was to evaluate the efficacy and safety ...
Subaşı Volkan V Physical Medicine & Rehabilitation Clinic, Private Özgüryaşam Physical Medicine & Rehabilitation Clinic, Okan merzeci bulvarı, no:538, Yenişehir/Mersin, Turkey, - - 2014
The aim of the study was to compare the efficacy of kinesiological taping and subacromial injection therapy in patients with subacromial impingement syndrome (SIS). Seventy patients diagnosed with SIS were randomly assigned to group 1 (n = 35, injection group) or group 2 (n = 35, kinesiological taping group). Betamethasone plus prilocaine was injected ...
Niu Junjie J Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, PR - - 2014
The instantaneously recovered stability and strength following vertebral augmentation prevent continuous micro-motion and further collapse of fractured vertebrae. Despite this, during follow-up of our patients, we observed recompression of augmented vertebrae with significant vertebral height loss and aggravation of local kyphotic deformity. To identify the risk factors related to recompression ...
Bülhoff Matthias M Center for Orthopaedics and Trauma Surgery, University of Heidelberg, Heidelberg, - - 2014
Studies evaluating the return to sports and work after shoulder arthroplasty are rare, and there are no studies evaluating return to work after total shoulder arthroplasty (TSA). Patients undergoing TSA will be able to return to their preoperative sports levels and occupations. Case series; Level of evidence, 4. A total ...
Kim Yong Joon YJ Department of Ophthalmology, Soonchunhyang University College of Medicine, Soonchunhyang University Seoul Hospital, Seoul, 140-210, Korea (South), Republic - - 2014
To evaluate the angiographic features of the affected limbus in patients with pterygia and assess limbal reconstruction outcomes after limbal-conjunctival autograft (LCA) transplantation in terms of vascular remodeling. Thirty-one eyes of 31 patients who underwent pterygium excision and LCA transplantation were studied prospectively. Twenty-eight eyes of 28 normal participants were ...
Ekwueme Osa-Eloka Christiandolus - - 2014
Nigeria ranks 10 out of the 22 countries in the world with the highest TB burden. Contact tracing enhances case finding and increases the probability of cure. The purpose of the study is to improve the contact tracing skills of tuberculosis patients at the major TB centre in Enugu State, ...
Brod Meryl - - 2014
Adult Growth Hormone Deficiency (AGHD) is a debilitating condition resulting from tumors, pituitary surgery, radiation of the head, head injury, or hypothalamic-pituitary disease. This qualitative study was conducted to better understand the multi-faceted impacts and treatment effects of GHD on adult patients' daily lives.Seven focus groups and four telephone interviews ...
Chaplin Emma E Centre for Exercise and Rehabilitation Science, NIHR Leicester Respiratory BRU, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom (Ms Chaplin); Pulmonary Rehabilitation Department, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom (Ms Gibb and Drs Sewell and Singh); and Faculty of Health and Life Sciences, Coventry University, Coventry, United Kingdom (Dr - - 2014
The COPD Assessment Tool (CAT) has previously been shown to be a sensitive outcome measure for pulmonary rehabilitation (PR) in a stable population, but its utility in a postexacerbation PR population is unknown. The aim of this study was to investigate any differences in response to the CAT between stable ...
Sureka Sanjoy Kumar SK Sanjay Gandhi Postgraduate Institute of Medical Sciences, Department of Urology and Renal transplantation , Department of Urology and Renal transplantation Sanjay Gandhi Postgraduate Institute of Medical Sciences Raebareli Road, Lucknow-U.P. 216014- INDIA , lucknow, U.P, India , 226014 , : 91-522-249-4110 ; - - 2014
Background: Etiology of orchialgia or testicular pain after laparoscopic donor nephrectomy (LDN) has been found to be related to injury of spermatic plexus during gonadal (testicular) vein (GV) or ureteral ligation. This study was aimed to evaluate and validate the impact of level of ligation of GV & ureter in ...
Dickschas Jörg J Klinik für Orthopädie und Unfallchirurgie, Klinikum Bamberg, - - 2014
Various pathologies of the hip or knee, such as patellofemoral malalignment or femoroacetabular impingement may be caused by a femoral torsional deformity. When diagnosed and analyzed, it is treated by femoral torsional osteotomy. Thirty femoral torsional osteotomies in 25 patients were included, the principal symptoms were patellar dislocation in 15 ...
Teixidor Viñas Mireia M Saint George's Hospital, - - 2014
Morbidly adherent placenta (MAP) is traditionally treated by hysterectomy with expected massive postpartum haemorrhage (PPH). In 2007, we instituted a policy of bilateral prophylactic occlusion balloon catheters placed in both internal iliac arteries followed by caesarean section with non-placental separation and preservation of the uterus. In 2010, the surgical technique ...
Scheid Christof C University Hospital of Cologne, Cologne, - - 2014
Approximately 15% of multiple myeloma (MM) patients exhibit a t(4;14) translocation, which often results in constitutive activation of the receptor tyrosine kinase (RTK) fibroblast growth factor receptor 3 (FGFR3). This study evaluated the efficacy and safety of dovitinib, an RTK inhibitor with in vitro inhibitory activity against FGFR, in patients ...
Nishina Naoshi N Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine , Tokyo , - - 2014
Objectives. To investigate the clinical effectiveness of tocilizumab (TCZ), a monoclonal antibody against the interleukin-6 receptor, in preventing relapse in patients with adult-onset Still's disease (AOSD). Methods. This retrospective study included clinical data from 40 patients who underwent regular follow-up at our institution in June 2013. Among these patients, 10 ...
Mohaddes Maziar M Department of Orthopedics , Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg; the Swedish Hip Arthroplasty Register, Gothenburg , - - 2014
Background and purpose - The use of trabecular metal (TM) cups in revision surgery has increased worldwide during the last decade. Since the introduction of the TM cup in Sweden in 2006, this design has gradually replaced other uncemented designs used in Sweden. According to data from the Swedish Hip ...
Abdel-Ghaffar Hala Saad HS Assisstant professor in Anesthesia and intensive care department, faculty of medicine, Assiut university, - - 2014
To evaluate the risk of peri-operative bleeding and re-intervention with peritonsillar lornoxicam infiltration in pediatric tonsillectomy. Prospective, randomized, double-blinded, placebo-controlled, split-body study. university hospital. 68 patients (7-15 y), ASA I-II scheduled for tonsillectomy divided into two groups (n=34) to receive bilateral peritonsillar saline infiltration (Placebo group), or peritonsillar saline infiltration ...
Mastoris Ioannis I The Zena and Michael A. Wiener Cardiovascular Institute, the Icahn School of Medicine at Mount Sinai, New York, New - - 2014
The first transcatheter aortisc valve replacement (TAVR) was performed in 2002, and has been proven beneficial in inoperable and high-risk patients for open heart surgery. Stroke occurrence after TAVR, both periprocedure and at follow-up, has not been well described. We sought to review incidence, pathophysiology, predictors, prognosis, and current preventive ...
Saliba Issam I Division of Otolaryngology-Head and Neck Surgery, Montreal University Hospital Center (CHUM), University of Montreal, Montreal, Quebec, Canada - - 2014
To compare the effectiveness of the endolymphatic duct blockage (EDB) and the endolymphatic sac decompression (ESD) to control Ménière's disease symptoms and to evaluate their effect on hearing level. Prospective nonblinded randomized study. Tertiary medical center. Fifty-seven patients affected by a refractory Ménière's disease were included out of which 22 ...
Gursu Sarper S Baltalimani Metin Sabanci Bone and Joint Diseases Hospital, Istanbul, Turkey - - 2014
Severe equinovarus foot deformity in adults is a challenging problem. Conservative treatment rarely is effective, and operative options are limited. The aim of this study was to evaluate the results of talectomy and tibiocalcaneal arthrodesis with intramedullary nail fixation for the treatment of severe equinovarus deformity in adults. Twelve patients ...
Silva M G Amila N MG Department of Orthopaedic Surgery, Singapore General Hospital, Singapore - - 2014
The prevalence of tibialis posterior tendon dysfunction (PTTD) is estimated to be as high as 3% to 4% in Western populations, and it is one of the most commonly misdiagnosed conditions of the foot and ankle. Clinical and radiological outcomes were assessed in grade IIB PTTD treated with a medializing ...
Subbu Raj R Institute of Sport Exercise and Health, University College London Hospitals, London, UK - - 2014
Avulsion of the proximal hamstring origin is well documented, and surgical treatment is advocated for complete avulsions. To compare the return to preinjury level of sport and the complexity of surgery in athletes undergoing surgical intervention for complete proximal hamstring avulsions within 6 weeks, 6 months, and after 6 months ...
Calvo Rafael R Orthopaedic Surgery Department, Clínica Alemana Santiago, Santiago, - - 2014
The treatment of anterior cruciate ligament (ACL) injuries in skeletally immature patients is controversial. Current evidence supports the view that surgical techniques restore knee stability and prevent progressive articular damage. However, most of the studies on this topic are small case series or they have short- or medium-term follow-up times. ...
Müller-Stich Beat P BP *Department of General, Visceral and Transplantation Surgery †Institute of Medical Biometry and Informatics ‡Study Center of the German Surgical Society (SDGC) §Department of Internal Medicine I and Clinical Chemistry, University of Heidelberg, Heidelberg, Germany ¶Department of Surgery, Kantonsspital St Gallen, Rorschacher Strasse 95, CH-9007 St Gallen, - - 2014
To compare surgical versus medical treatment of type 2 diabetes mellitus (T2DM) remission and comorbidities in patients with a body mass index (BMI) less than 35 kg/m. Obesity surgery can achieve remission of T2DM and its comorbidities. Metabolic surgery has been proposed as a treatment option for diabetic patients with ...
Tornero Eduard E Department of Traumatology and Orthopaedic Surgery. Hospital Clínic of - - 2014
The aim of this study was to compare the prosthetic joint infection (PJI) rate after total joint arthroplasty in two consecutive periods with different antibiotic prophylaxis: cefuroxime versus cefuroxime plus teicoplanin. We retrospectively reviewed 1897 patients who underwent THA or TKA between March 2010 and February 2013. From March 2010 ...
Han Jinu J Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, - - 2014
To investigate long-term strabismus surgical outcomes and visual prognosis in preadolescent ocular myasthenia gravis (OMG). The medical records of all patients with preadolescent onset OMG who underwent strabismus surgery were reviewed. Thirteen patients met the study inclusion criteria. The main outcomes, including ocular alignment, number of surgeries, and visual acuity ...
Koyama Yutaka Y Department of Cardiovascular Surgery, Toyohashi Heart Center, 21-1 Gobutori, Oyama-cho, Toyohashi, Aichi, 441-8530, Japan, - - 2014
As transcatheter aortic valve implantation (TAVI) may become a potential treatment for high-risk patients with aortic stenosis (AS), evaluation of outcomes after open aortic valve replacement (AVR) in elderly patients is warranted. We documented early and late outcomes after isolated AVR in octogenarians compared with younger age groups. From January ...
Matsuyama Hideyasu H Department of Urology, Graduate School of Medicine, Yamaguchi University, Ube, Yamaguchi, - - 2014
To determine the feasibility of vesicourethral anastomosis using running suture during retropubic radical prostatectomy and to compare the surgical outcomes of vesicourethral anastomosis using running suture with those of the standard interrupted suture technique. A total of 60 patients undergoing radical prostatectomy from 2010 to 2012 at the Yamaguchi University ...
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