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McMillan Alison A Academic Unit of Sleep and Ventilation, National Heart and Lung Institute, Imperial College London, London, UK; Respiratory Disease Biomedical Research Unit at the Royal Brompton Hospital and Harefield NHS Foundation Trust, London, - - 2014
The therapeutic and economic benefits of continuous positive airway pressure (CPAP) for moderate to severe obstructive sleep apnoea (OSA) syndrome have been established in middle-aged people; however, the benefits in older people are unknown. This trial was designed to address this evidence gap. This 12-month, multicentre, randomised trial enrolled patients ...
Liu Jianjun - - 2014
Abstract Objective: To compare the efficacy of IPL (540-950nm) in treating different erythema associated with rosacea. Methods: Thirty-two patients with erythematotelangiectatic rosacea (ETR, n=16) and papulopustular rosacea (PPR, n=16) were recruited. Three treatments of IPL (540-950nm) were administered on the face at 3-weeks intervals. Clinical improvement in erythema was independently ...
Park Hyoung Keun HK Konkuk University, School of Medicine, Urology, Seoul, Korea, Republic of ; - - 2014
Objectives: To minimize stent-related symptoms, the proximal part of the PolarisTM stent is composed of a firm material and its distal part is composed of a soft material. The aim of this study was to compare stent-related symptoms of Polaris and Percuflex stents using and to assess the impacts of ...
Wakefield Thomas W TW University of Michigan, Ann Arbor, MI - - 2014
Patients presenting with DVT in the absence of any identifiable risk factors are said to have an unprovoked or idiopathic DVT. Recurrent events are much more common in these patients (10% vs. ≤ 3% at 1 year) compared to patients with a DVT provoked by a reversible risk factor, and ...
Melson Timothy I TI Institution: Helen Keller Hospital, Sheffield, Alabama, - - 2014
Problems with intravenous patient-controlled analgesia (IV PCA) are well known, including invasive route of delivery and pump programming errors. The primary objective of this study was to evaluate patient satisfaction with a novel sublingual sufentanil PCA system (sufentanil sublingual tablet system 15 mcg with a 20-minute lockout interval; SSTS) to IV ...
Calleja Henry H Christine M. Kleinert Institute for Hand and Microsurgery, Louisville, Kentucky, USA , University of Louisville, Louisville, Kentucky, - - 2014
We compared carpal tunnel release using a radial sided approach (RCTR) with a two-incision approach with regards to complications, grip strength, and functional outcomes. Retrospective chart review was done and data was collected pre-operatively, and post-operatively at six weeks and three months. A total of 32 and 26 patients were ...
Reser Diana D Department for Cardiovascular Surgery, University Hospital Zürich, Zürich, - - 2014
Minimally invasive mitral valve surgery (MIMVS) through a right lateral thoracotomy has emerged as another option in cardiac surgery. We present our single center experience with regards to repair rate and durability of the repair in patients undergoing MIMVS. Between January 2009 and December 2012 a total of 312 consecutive ...
Schroeder Andreas Sebastian AS Department of Pediatric Neurology and Developmental Medicine, Hauner Children's Hospital, University of Munich, Munich, Germany; German Center of Vertigo and Balance Disorders, IFBLMU, University of Munich, Munich, - - 2014
The aim of the study was to evaluate patient-specific determinants of responsiveness to robot-enhanced repetitive treadmill therapy (ROBERT) in patients with early-developed movement disorders. Patients were treated over 12 sessions during a 3-week period. Gross Motor Function Measure-66 (GMFM-66) scores 1 day before ROBERT were compared with scores recorded 1 ...
Artzi Ofir O Department of Dermatology, Chaim Sheba Medical Center, Ramat Gan, - - 2014
Bacterial skin infection is a common dermatologic problem in travelers, which usually resolves without sequela. In contrast, post-travel recurrent furunculosis (PTRF) is a new unique entity of a sequential occurrence of many furuncles seen after returning home from a trip to the Tropics. The objective of this study was to ...
Desch Steffen S Department of Internal Medicine/Cardiology, Angiology, Intensive Care Medicine, University of Luebeck, Luebeck, - - 2014
In patients with left-sided native-valve infective endocarditis (IE), the risk of embolism is increased with a vegetation size ≥10 mm. For this reason-according to guidelines-surgery may be considered in patients with isolated large vegetations (without any other indication for surgery). However, the value of surgery in this patient subset has never ...
Povlsen Bo B London Hand Clinic, London Bridge Hospital, London, - - 2014
The purpose of this study was to compare the initial and final outcome range of motion in the MCP-J and PIP-J of single digit Dupuytren's Contracture treated with either open surgical excision or manipulation after collagenase clostridium histolyticum (CCH; Xiapex) injection. Material: Ten patients in either group. The range of ...
Petersen A H AH National Allergy Research Centre, Copenhagen University Hospital Gentofte, Niels Andersens Vej 65, DK-2900, Hellerup, - - 2014
Hand eczema is recognized as a long-lasting disease with personal and societal repercussions. Long term studies are required to generate information on factors contributing to a poor outcome. The aims of this seven year follow-up study were to evaluate the clinical course of patients with hand eczema, the occupational consequences ...
Uchida Daisuke D *Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences †Department of General Internal Medicine 2, Kawasaki Hospital, Kawasaki Medical School ‡Department of Endoscopy, Okayama University Hospital, Okayama, - - 2014
The treatment of biliary stricture is crucially important for continuing stable chemotherapy for unresectable biliary carcinoma; however, there is no consensus regarding the use of hilar biliary drainage. In this study, we examined the efficacy of endoscopic over 3-branched biliary drainage using self-expandable metallic stents (SEMSs) in patients with unresectable ...
Fernando Ka K Department of Genitourinary Medicine, Staffordshire and Stoke-on-Trent Partnership NHS Trust, Cobridge Community Health Centre, Stoke-on-Trent, UK - - 2014
To assess the outcome of routine sexually transmitted infection re-screening after a three-month interval in unselected patients diagnosed with gonorrhoea. We sought to assess whether this active approach would result in an increase in the number of people attending clinic and subsequently diagnosed with gonorrhoea re-infection, compared with normal re-presentation ...
Siswojo Andy Sisnata AS Department of Anaesthesia, Box Hill Hospital, Box Hill, Victoria, Australia. Electronic address: - - 2014
To investigate whether the pleth variability index (PVI), derived noninvasively from a pulse oximeter probe, would predict fluid responsiveness in patients undergoing noncardiac surgeries. A clinical, prospective, observational study. Operating room of a tertiary care hospital. Twenty-nine adult patients undergoing a range of noncardiac surgeries, requiring general anesthesia, tracheal intubation, ...
Tartaglia F F Department of Surgical Sciences - "Sapienza" University of Rome, Rome, Italy. Electronic address: - - 2014
In the English literature there is no single definition that identifies elderly patients. In our retrospective study, we divided total thyroidectomized patients operated on from 2000 to 2010 in the Department of Surgical Sciences of the "Sapienza" University of Rome, in two groups: group 1 consists of 448 patients over ...
Durst C R CR Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, VA, USA. Electronic address: - - 2014
To compare the complications and outcomes of Neuroform and Enterprise stents in the treatment of unruptured wide-necked aneurysms. Under the auspices of the institutional review board, a review of a prospectively collected patient log identified 130 patients who underwent elective stent-assisted coil embolization of a wide-necked aneurysm, including 53 patients ...
Pezawas Thomas T Department of Cardiology, Medical University of Vienna, Austria. Electronic address: - - 2014
Pulmonary vein isolation (PVI) has become an accepted therapy for patients with atrial fibrillation (AF) and the indications have widened to include non-paroxysmal AF-patients. Maintenance of sinus rhythm after PVI can be adversely affected by clinical or echocardiographic parameters, which should be clearly identified. After baseline clinical and echocardiographic evaluations, ...
Xue Xiao-Dong XD Department of Cardiovascular Surgery, Shenyang Northern Hospital, 83 Wenhua Road, Shenhe District, Shenyang, 110016, Liaoning, - - 2014
Patients with rheumatic heart disease (RHD) often experience persistent atrial fibrillation (AF) associated with adverse atrial structural remodeling (ASR) manifested by atrial fibrosis and left atrial enlargement. The aim of this study was to explore the potential molecular signaling mechanisms for atrial fibrosis and ASR. Twenty RHD patients with persistent ...
Prapasrivorakul S S Department of Colorectal Surgery, Oxford Pelvic Floor Centre, Churchill Hospital, Oxford University Hospitals, Oxford, OX3 7LJ, - - 2014
Prior to implantation of an expensive sacral nerve stimulator, a 'screening phase' is undertaken. This report examines the feasibility of temporary sacral neuromodulation under local anaesthesia in an outpatient setting. We report on our technique, results and patient satisfaction. Percutaneous nerve evaluation was performed in 184 patients using a new ...
Kypta Alexander A Cardiovascular Division, Department of Internal Medicine I, General Hospital Linz, Linz, - - 2014
Device replacements bear many potential risks for patients. Electrocautery should be used cautiously because of heating of the cautery tip which may lead to insulation melting. The PEAK PlasmaBlade™ (Medtronic Inc., Minneapolis, MN, USA) uses a novel technology to cut tissue. The objective of this study was to evaluate if ...
Nomi Takeo T Department of Digestive Disease, Institut Mutualiste Montsouris, Université Paris-Descartes, 42 Boulevard Jourdan, 75014, Paris, France, - - 2014
The incidence of colorectal cancer liver metastases (CRLM) among elderly patients has increased; therefore, older patients are increasingly being considered for hepatic resection. However, data regarding the outcome of laparoscopic major hepatectomy (LMH) in elderly patients are limited. The aim of this study was to evaluate the safety and feasibility ...
Caruso Angelo A Digestive Endoscopy Unit, Baggiovara Hospital, Viale Giardini 1355, 41100, Modena, Italy, - - 2014
Some patients with benign colorectal obstruction do not respond to endoscopic balloon dilation. Fully covered self-expandable metal stents (FCSEMSs) have several potential advantages over non-covered stents, including a higher likelihood of retrieval owing to limited local tissue reaction. However, the efficacy and safety of FCSEMSs in benign colorectal strictures have ...
Zogg Stefanie - - 2014
The Global Initiative for Chronic Obstructive Lung Disease proposed in 2011 a new system to classify chronic obstructive pulmonary disease (COPD) patients into risk groups A-D, which considers symptoms and future exacerbation risk to grade disease severity. The aim of this study was to investigate the agreement between COPD risk ...
Iafrate F F Department of Radiological Oncological and Pathological Sciences, "Sapienza" University of Rome, Rome, Italy, - - 2014
To compare two regimens of reduced bowel preparation and faecal tagging for CT colonography. Single centre, prospective, randomized, noninferiority study, in which 52 consecutive adults underwent routine CT colonography. Patients, following a three-day low-fibre diet, received one of the two reduced preparations: 1-L polyethylene glycol and four tablets of bisacodyl ...
Dubory Arnaud A Tumor and Spine Unit, Orthopaedic Department, Bicêtre University Hospital, AP-HP Paris, 78 Rue du Général Leclerc, 94270, Le Kremlin-Bicêtre, France, - - 2014
To investigate the incidence of surgical-site infection (SSI) and determinate the risk factors of SSI in the context of spinal injury. From February 1, 2011 to July 31, 2011, for a multicentre cohort of patients with acute spinal injury, we prospectively censored those with SSI for at least 12 months. We ...
Leng Xi-Sheng XS Department of Surgery, Peking University People's Hospital, Beijing, China - - 2014
Our purpose was to evaluate ertapenem versus ceftriaxone/metronidazole for prophylaxis of surgical site infections (SSIs) following elective colorectal surgery in Chinese adult patients. Eligible Chinese adults aged 18-80 years scheduled to undergo elective colorectal surgery by laparotomy were randomized to receive a 30 min infusion of 1 g of ertapenem/metronidazole ...
Cocito Dario D Department of Neuroscience, University of Turin, Via Cherasco 15, 10126, Turin, Italy, - - 2014
This multi-center Italian prospective observational study reports the 4 months follow-up data of 87 patients affected by chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and multifocal motor neuropathy (MMN) shifted from intravenous to subcutaneous immunoglobulin treatment. A therapeutic shift from intravenous to subcutaneous immunoglobulin was performed in 87 patients (66 CIDP; 21 MMN) ...
Kim Mia M Department of General, Gastrointestinal, Vascular and Paediatric Surgery, University Hospital Wuerzburg, Oberduerrbacher Str. 6, 97080, Wuerzburg, - - 2014
Reported recurrence rates after perineal rectosigmoidectomy (Altmeier's procedure) in patients with full-thickness rectal prolapse vary from 0-60%. The object of this study was to analyze risk factors for recurrence after this procedure. From May 2004 to December 2012, 63 consecutive patients suffering from full-thickness rectal prolapse undergoing perineal rectosigmoidectomy were ...
Pellino Gianluca G Department of Medical, Surgical, Neurologic, Metabolic and Ageing Sciences, Second University of Naples, Naples, Italy. Electronic address: - - 2014
Restorative proctocolectomy (RP) with ileal pouch-anal anastomosis is the mainstay treatment for intractable or refractory ulcerative colitis (UC). Safety and effectiveness of IPAA in elderly patients are debated. Our aim was to compare surgical outcomes and function of patients undergoing IPAA over 80-year-of-age with those of younger controls. We retrospectively ...
Khan Fatima F Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, - - 2014
The risk of recurrent venous thromboembolism (VTE) must be weighed against the risk of bleeding in deciding to keep patients on extended anticoagulation with vitamin K antagonists (VKAs). Most of the studies of risk of bleeding on VKAs are randomized controlled trials of highly selected patients followed for less than ...
Elmadağ M M Department of orthopaedics and traumatology, School of medicine, Bezmialem Vakıf university, Adnan Menderes Boulevard (Vatan street), 34093 Fatih, İstanbul, - - 2014
The modified Stoppa approach was introduced to manage fracture of the anterior column instead of the ilioinguinal approach to reduce morbidity. However there is no clinical evidence to confirm its efficiency. Therefore this study was designed to ascertain: (1) if the Stoppa approach versus ilioinguinal allows less blood loss, (2) ...
Fu Zhenhong Z Department of Cardiology, Hainai Branch of Chinese People's Liberation Army General Hospital, Sanya, Hainan, People's Republic of China; Department of Cardiology, Chinese People's Liberation Army General Hospital, Beijing, People's Republic of - - 2014
The relationship between hyporesponsiveness to clopidogrel and in stent restenosis (ISR) was analyzed, and the cut-off value of hyporesponsiveness to clopidogrel for ISR was evaluated. Design and Methods 861 consecutive patients enrolled and patients' inhibition rates in arachidonic acid (AA) and adenosine 5'-diphosphate (ADP) pathways were measured by thrombelastography (TEG) ...
Bellomo Rinaldo R Austin Hospital, Heidelberg, Vic., - - 2014
Background and Aims: We aimed to examine the association between daily protein intake (DPI) and outcomes in patients from the Randomized Evaluation of Normal versus Augmented Level (RENAL) trial. Methods: We analyzed the association between DPI and clinical outcomes using multivariable logistic regression, Cox proportional hazards models and time-adjusted analysis. ...
Watanabe Satoru S Department of Laboratory Sciences, Course of Health Sciences, Gunma Graduate School of Health Sciences, Maebashi, - - 2014
Introduction: In some previous studies, vitamin B12 treatment showed immunomodulatory effects and restored the immunological abnormalities in patients with pernicious anemia (PA). In the present study, peripheral blood T cell subsets, including regulatory T cells (Tregs), were examined before and after vitamin B12 treatment in PA patients. Patients and Methods: ...
Liu Ling L Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, - - 2014
Objective: To investigate the effectiveness of the Shikani optical stylet (SOS) and GlideScope video laryngoscope (GVL) for tracheal intubation of thyroid tumor patients with a difficult airway. Subjects and Methods: One hundred and twenty thyroid tumor patients with a difficult airway, who were undergoing elective surgery requiring general anesthesia, were ...
Lisowska Anna A Departament of Cardiology, Medical University of Bialystok, Ul. Skłodowskiej 24A, 15-276, Białystok, Poland, - - 2014
Access-site vascular complications in patients undergoing transradial coronary procedures are rare but may have relevant clinical consequences. The aim of the study was to evaluate: (1) radial artery's (RA) patency immediately after the procedure and in long-term observation, (2) factors influencing the frequency of radial artery's occlusion (RAO) after percutaneous ...
Kodjikian Laurent L Service d'ophtalmologie, Hospices Civils de Lyon, Groupement Hospitalier Nord, Hôpital de la Croix-Rousse, 103 Grande Rue de la Croix-Rousse, F-69317, Lyon Cedex 04, France, - - 2014
Neovascular age-related macular degeneration (AMD) is the main cause of central vision loss among individuals aged 50 years or older in developed countries. The aim of this study was to review systematically the effect of bevacizumab compared to ranibizumab in patients with AMD at 1 year. A systematic review was performed on ...
Dupont-Lucas C C Département de Pédiatrie, Centre Hospitalier Universitaire de Caen, Caen, France; Université de Basse Normandie, Caen, - - 2014
It is reported that 27-54% of paediatric patients with perianal Crohn's disease (CD) do not respond to infliximab (IFX). To identify predictors of response to IFX in paediatric perianal CD. A retrospective cohort study of 101 paediatric patients treated with IFX between 2000 and 2011 for perianal CD in 22 ...
Eren Sabri Baki SB Department of Otorhinolaryngology, Bezmialem Vakif University, Fatih, Istanbul, - - 2014
A prospective endoscopic and radiologic evaluation of long-term outcomes of crushing and crushing with intrinsic stripping, 2 minimally destructive techniques used for the surgical treatment of concha bullosa. Forty-two patients who underwent concha bullosa surgery (a total of 55 conchae surgeries) were included in the study. The patients were allocated ...
Chai-Adisaksopha Chatree C Department of Medicine, McMaster University, Hamilton, ON, - - 2014
Vitamin K antagonists (VKAs) have been the standard of care for treatment of thromboembolic diseases. Novel oral anticoagulants (TSOACs) have been developed and found to be at least non-inferior to VKAs with regards to efficacy but the risk of bleeding with TSOACs remains controversial. We performed a systematic review and ...
Tabrizi Reza R From the *Department of Oral and Maxillofacial Surgery, Shahidbeheshti University of Medical Sciences, Tehran, Iran; and Departments of †Oral and Maxillofacial Radiology and ‡Dentistry, Shiraz University of Medical Sciences, Shiraz, - - 2014
Odontogenic keratocysts (OKCs) have high recurrence potential. The aim of the study is to evaluate the correlation of radiographic features and treatments with the frequency of recurrence in OKCs in the mandible. This is a cohort retrospective study. The size of the lesions was measured on orthopantomography. Radiographic features (unilocular ...
Komar Monika M Department of Cardiac and Vascular Diseases, Institute of Cardiology, Jagiellonian - - 2014
Background:The aim of this study was to prospectively perform ambulatory 24-h ECG monitoring to assess the effects of transcatheter closure of atrial septal defect (ASD).Methods and Results:A total of 235 consecutive subjects (female, n=163; male, n=72; age, 44.6±14.4 years) were enrolled in the study, who were due undergo ASD closure. Holter monitoring ...
Kosiuk Jedrzej J Department of Electrophysiology, Heart Center - - 2014
Background:The incidence of postoperative complications following pacemaker or implantable cardioverter-defibrillator implantations in patients treated with new oral anticoagulation agents has not been studied. Here we present a first comparison of complications after cardiac rhythm device (CRD) implantations in patients with atrial fibrillation (AF) treated with dabigatran or uninterrupted warfarin.Methods and Results:Using a ...
Singh Namita N Departments of *Pediatrics and †Medicine, Cedars-Sinai Medical Center, Los Angeles, California; ‡F. Widjaja Foundation Inflammatory Bowel and Immunobiology Institute, Cedars-Sinai Medical Center, Los Angeles, California; and §Department of Biostatistics, Cedars-Sinai Medical Center, Los Angeles, - - 2014
Low infliximab (IFX) trough levels and high anti-infliximab antibodies (ATI) levels are associated with loss of response to IFX. Optimizing IFX levels to maintain target concentrations before loss of response may improve long-term efficacy. We hypothesized that trough levels at week 14 are predictive of IFX durability. A prospective observational ...
Chen Min M *Department of Gastroenterology & Hepatology, Cleveland Clinic Foundation, Cleveland, Ohio; and †Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan, - - 2014
The response of Crohn's disease (CD) stricture to endoscopic therapy compared with non-CD stricture is unknown. Our aim was to compare the short- and long-term outcomes of endoscopic management of those strictures. All eligible patients with benign non-CD strictures who underwent the endoscopic balloon dilation between January 2002 and September ...
Kotani Yasuhiro Y Division of Cardiovascular Surgery, The Labatt Family Heart Centre, The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Surgery, University of Toronto, Toronto, Ontario, - - 2014
Extended end-to-end anastomosis (EEEA) through a left thoracotomy for coarctation of the aorta (CoA) and tubular hypoplasia of the aortic arch (THAA) leaves an unaugmented hypoplastic proximal aortic arch (PAA) segment, which may increase late reintervention for PAA obstruction. We sought to assess PAA growth and reintervention for PAA obstruction ...
Holubcova Zdenka Z Department of Cardiac Surgery, Charles University in Prague, Faculty of Medicine and University Hospital Hradec Kralove, Hradec Kralove, Czech - - 2014
Background The aim of this study was to compare the dynamics of two inflammatory response biomarkers pentraxin 3 (PTX3) and C-reactive protein (CRP) after cardiac surgery with particular regard to different postoperative clinical manifestation of inflammatory response. Patients and Methods In this study, 42 patients undergoing open heart surgery with the use ...
Shin Jason J JJ Department of Orthopaedics, Royal University Hospital, University of Saskatchewan, Saskatoon, SK, S7N 0W8, Canada, - - 2014
Irreparable ruptures of the subscapularis tendon lead to impaired function of the shoulder and presents a surgically complex problem. Transfer of the pectoralis major tendon has been reported as a possible treatment option. The purpose of this systematic review is to critically examine the outcomes of pectoralis major transfers for ...
Urlings T A J TA Department of Radiology, Medical Center Westeinde, Postbus 432, 2501 CK, The Hague, The Netherlands, - - 2014
The purpose of this study was to objectify and evaluate risk factors for thromboembolic complications after treatment with a Zenith(®) Low Profile Endovascular Graft (Zenith LP). Results were compared with those in the recent literature on endovascular aortic repair (EVAR) and with the thromboembolic complications in the patient group treated ...
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