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Cojutti Piergiorgio P Institute of Clinical Pharmacology, Azienda Ospedaliero-Universitaria Santa Maria della Misericordia, Udine, Italy Department of Experimental and Clinical Medical Sciences, University of Udine, Udine, - - 2014
To report on linezolid exposure in a paediatric population who routinely underwent therapeutic drug monitoring (TDM) for dosage optimization and to assess the factors affecting interpatient variability. We performed a retrospective study of patients whose plasma Cmin and Cmax levels were measured during linezolid treatment. Adequate exposure was defined as ...
Jalalian Rozita R Department of Cardiology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, IR - - 2014
Atrial Fibrillation (AF) is a common complication after open heart surgery and is frequently associated with increased hospital stay, complications, and mortality rates. The effect of β-blockers on prevention of supraventricular arrhythmias has been confirmed in several prospective randomized studies. This clinical trial aimed to compare the preventive effects of ...
Konerman Monica A MA Division of Gastroenterology, University of Michigan Health System, 3912 Taubman Center, 1500 East Medical Center Drive, SPC 5362, Ann Arbor, MI 48109, - - 2014
Large-volume paracentesis (LVP) can be time and labor intensive depending on the amount of ascites removed and the method of drainage. Wall suction has been adopted as the preferred method of drainage at many centers, though the safety and benefits of this technique have not been formally evaluated. The primary ...
Peles Einat E a Epidemiologist, The Dr. Miriam and Sheldon G. Adelson Clinic for Drug Abuse Treatment and Research, Tel Aviv Sourasky Medical Center; Sackler Faculty of Medicine , Tel Aviv University , Tel Aviv , - - 2014
Abstract Minority status is associated with mental and physical morbidity, substance dependence, and poor outcomes. To compare characteristics and treatment outcomes between patients from two minority groups in Israel (Christians and Muslims) and patients from the majority population (Jews) in methadone maintenance treatment (MMT), we prospectively studied all patients admitted ...
Ahmed Sheikh Sohail SS From the Department of Pediatrics, Riley Hospital for Children at Indiana University Health, Indiana University School of Medicine, and the Department of Biostatistics, Indiana University School of Medicine, - - 2014
Autism and autism spectrum disorders (A/ASD) represent a family of neurodevelopmental conditions that are associated with overactive, difficult-to-control behaviors. Sedating these patients for magnetic resonance imaging (MRI) poses challenges. Children with A/ASD were examined against clinical controls to determine the effectiveness and safety of intravenous (IV) dexmedetomidine for deep sedation. ...
Xie Guogang G Department of Respiratory Medicine, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai 200080, - - 2014
The Global Initiative for Chronic Obstructive Lung Disease (GOLD) presented a new ABCD group classification of chronic obstructive pulmonary disease (COPD). We aimed to examine the association of spirometric classification and the new GOLD classification with exacerbations, and to compare symptoms in different ways. We investigated 848 patients with stable ...
Vidović Bojana B University of Belgrade, Faculty of Pharmacy, Department of Bromatology, Belgrade, - - 2014
The purpose of this study was to examine the effects of alpha-lipoic acid (LA) supplementation on oxidative stress markers in patients with schizophrenia. Eighteen (18) medicated patients with schizophrenia and 38 healthy controls received daily supplements of LA (500 mg/day) for three months. At baseline, 45th and 90th days of ...
Faridi Pouya P Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy and Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, - - 2014
Kidney stones are one of the most common disorders of the urinary tract and cause a great deal of morbidity and economic loss. Because of the side effects and costs of current interventional procedures, researchers are interested in finding medicinal therapies. In this regard, some reports have focused on traditional ...
Fadel Fatina I - - 2014
Achieving dry weight after hemodialysis (HD) is critical as chronic fluid over-load can result in left ventricular hypertrophy, while small fluid shifts may result in intra-dialytic morbid events (IME). In the pediatric population, estimating dry weight can be difficult due to growth while on dialysis. Continuous non-invasive monitoring of the ...
Dogra Sunil S Department of Dermatology, PGIMER, Chandigarh, - - 2014
Postacne scarring is disfiguring, both physically as well as psychologically. Over the past two decades, multiple modalities for treatment of acne scars have emerged and microneedling with dermaroller is one of them. To evaluate the efficacy and safety of microneedling treatment for atrophic facial acne scars. Thirty-six patients (female - ...
Rudnick Benjamin B The Philadelphia Hand Center, P.C, Thomas Jefferson University, Philadelphia, PA - - 2014
Scaphoid excision and four-corner arthrodesis (FCA) is an acceptable motion sparing procedure used to treat wrist arthritis. Recently, a locking dorsal circular plate composed of polyether-ether-ketone has been introduced (Xpode®; TriMed Inc.). The purpose of this study is to assess the efficacy of this specific plate design with regard to ...
Wong Justin C JC Department of Orthopedic Surgery, Thomas Jefferson University, 1020 Walnut Street, College Building Rm 516, Philadelphia, PA 19107 - - 2014
Although injury to the collateral ligaments of the metacarpophalangeal joint (MPJ) of the fingers is less common than corresponding injuries in the thumb, similar disability may result from chronic untreated injuries. We evaluated injury characteristics and the outcome after primary repair of subacute to chronic grade III collateral ligament injuries ...
Sheikh Emran E 201 Route 17 North 11th Floor, Rutherford, NJ 07070 - - 2014
Stenosing tenosynovitis or trigger finger is a common clinical condition regularly treated with steroid injections. Varied success is reported at early time points following injection. We present a prospective, randomized IRB-approved study to confirm these findings at a long-term follow-up. Adult patients presenting with symptoms of stenosing tenosynovitis who agreed ...
Henry Mark M Hand and Wrist Center of Houston, 1200 Binz Street, 13th Floor, Houston, TX 77004 - - 2014
With advanced Kienböck's disease, hyaline cartilage delamination or bone fragmentation render the lunate unsalvageable. Common surgical options are proximal row carpectomy, scaphotrapeziotrapezoid fusion, scaphocapitate fusion, or total wrist fusion. The purpose of this study was to prospectively evaluate the clinical and radiographic outcomes of one alternative: lunate prosthetic replacement arthroplasty ...
Means K R KR Jr The Curtis National Hand Center, MedStar Union Memorial Hospital, 3333 North Calvert Street, Baltimore, MD 21218 - - 2014
There is limited published information about long-term outcomes and recurrence rates following single-portal endoscopic carpal tunnel release. We reviewed symptom and function outcomes from a prospectively collected database of patients who underwent single-portal endoscopic carpal tunnel release at a minimum of 8 years follow-up. Out of 207 patients in the original ...
Terzis Julia K JK Department of Plastic Surgery, New York University Medical Center, New York, NY USA ; International Institute of Reconstructive Microsurgery, 27-28 Thomson Ave., Long Island City, NY 11101 - - 2014
Scapular position and size deficiency is evident in obstetric brachial plexus paralysis (OBPP) patients due to the absence of balanced muscular forces acting on the scapula. Scapula stabilization (SS) procedures aim to restore a balanced musculature and anatomic position and to augment shoulder function and enhance developmental potential. Retrospective chart ...
Yaffe Mark A MA Department of Orthopedic Surgery, Northwestern University Feinberg School of Medicine, 676 N. St. Clair, Suite 1350, Chicago, IL 60611 - - 2014
The purpose of the present study is to evaluate a single surgeon's short, intermediate, and long-term clinical, functional, and radiographic outcomes with a trapeziectomy with flexor carpi radialis (FCR) suspension arthroplasty without tendon interposition (LRSA). Twenty-one patients underwent 26 FCR suspension arthroplasties without tendon interposition by a single senior surgeon. ...
Cobb Tyson K TK Orthopaedic Specialists, Inc, 3385 Dexter Court, Davenport, IA 52807 - - 2014
The objective was to evaluate recovery characteristics of patients undergoing endoscopic cubital tunnel release (ECuTR) by determining the following: (1) return to work (RTW) times following ECuTR compared with RTW times of patients that underwent anterior transposition of the ulnar nerve (ATUN), (2) satisfaction rates and factors affecting satisfaction, (3) ...
Hsu Chih-Chieh CC Gastrointestinal Stromal Tumor Team, Department of Surgery, Chang Gung Memorial Hospital, Linkou, Taiwan, - - 2014
Imatinib mesylate (IM) is effective in metastatic gastrointestinal stromal tumor (GIST) patients; however, disease progression eventually occurs due to IM resistance or intolerance. Treatment options include IM escalation or a direct shift to sunitinib, but comparison of these strategies is required. This study included 91 out of 214 metastatic GIST ...
Bateman D N DN National Poisons Information Service (Edinburgh) & Royal Infirmary of Edinburgh , Edinburgh , - - 2014
Abstract Background. On 3 September 2012, the licensed indication for acetylcysteine was changed in the United Kingdom (UK) so that all patients with a plasma paracetamol concentration above a "100 mg/L" (4 h post ingestion) nomogram treatment line after an acute paracetamol (acetaminophen) overdose should be treated. This is a ...
Pennington N N NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals Trust, - - 2014
Total hip replacement (THR) is successful and performed commonly. Component placement is a determinant of outcome. Influence of surgeon handedness on component placement has not been considered previously. This study was a radiographic assessment of component positioning with respect to handedness. Early data from 160 patients are reported. Overall, 160 ...
Banglawala Sarfaraz M SM Division of Rhinology and Sinus Surgery, Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, - - 2014
The impact of intraoperative hydrodebrider sinus irrigation (HSI) during endoscopic sinus surgery (ESS) on postoperative inflammation, endoscopy, and patient-reported outcomes has not been studied. A clinical trial of 12 patients with symmetric chronic rhinosinusitis were prospectively randomized to HSI on one side after undergoing bilateral ESS. The contralateral side was ...
Lee Doh Young DY Department of Otorhinolaryngology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South - - 2014
There have been very few studies on the prognosis of postviral olfactory dysfunction. The aim of the study was to evaluate its long-term prognosis and factors influencing the prognosis. This study included patients who were diagnosed with postviral olfactory dysfunction at least one year ago in a Smell and Taste ...
Toomey Paul P Florida Hospital Tampa, Tampa, Florida, - - 2014
Transoral incisionless fundoplication (TIF) was U.S. Food and Drug Administration-approved in 2007 to treat gastroesophageal reflux disease (GERD), but comparative data are lacking. This study was undertaken to compare outcomes for patients with GERD undergoing TIF versus laparoscopic Nissen or Toupet fundoplications. We undertook a case-controlled study of three cohorts ...
Kaliyadan Antony A Jefferson Heart Institute, 925 Chestnut Street, Mezzanine, Philadelphia, PA 19107 USA. - - 2014
A serious long-term complication of drug-eluting stent (DES) implantation is the occurrence of very late stent thrombosis (VLST) beyond 1 year after implantation. While VLST has been observed as late as 3 to 5 years following the initial procedure, it remains unknown whether DES thrombosis is a finite phenomenon that ...
Lee Michael S MS UCLA Medical Center, 100 Medical Plaza, Suite 630, Los Angeles, CA 90095 USA. - - 2014
Although percutaneous coronary intervention with everolimus-eluting stent (EES) implantation for native coronary artery disease has favorable results compared to first-generation drug-eluting stents, outcomes with EES for the treatment of in-stent restenosis (ISR) are unknown. The Xience V USA is a prospective multicenter registry evaluating outcomes in patients treated with EES. ...
Kasel Albert M AM Department of Cardiovascular Disease, Deutsches Herzzentrum München, Lazarettstraße 36, 80636 Munich, Germany. - - 2014
To provide a simplified, standardized methodology for a successful transfemoral transcatheter aortic valve replacement (TAVR) procedure with the Sapien XT valve in patients with severe aortic stenosis (AS). TAVR is currently reserved for patients with severe, symptomatic AS who are inoperable or at high operative risk. In many institutions, TAVR ...
Cheung Kin W KW Department of Orthopaedics and Traumatology, Prince of Wales Hospital, Shatin - Hong - - 2014
Avascular necrosis (AVN) of the hip may have extensive involvement of the proximal femur which may affect boney ingrowth into cementless femoral stems. From 1994 to 2004, 182 total hip arthroplasties (in 144 patients, 117 AVN hips and 65 non-AVN hips) were performed using hydroxyapatite coated femoral stems. All patients ...
Kawamura Hideki H 1 Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Sapporo, - - 2014
Abstract Laparoscopic gastrectomy has the advantage of early recovery at the initial phase after surgery. However, there are only few reports of mid- or long-term observations of patients' quality of life. In all, 254 Stage IA or IB [laparoscopy-assisted distal gastrectomy (LADG): 177, open distal gastrectomy (ODG): 77] patients were ...
Boulle Andrew A Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; Department of Health, Provincial Government of the Western Cape, Cape Town, South - - 2014
High early mortality in patients with HIV-1 starting antiretroviral therapy (ART) in sub-Saharan Africa, compared to Europe and North America, is well documented. Longer-term comparisons between settings have been limited by poor ascertainment of mortality in high burden African settings. This study aimed to compare mortality up to four years ...
Duracinsky Martin - - 2014
Facial lipoatrophy is a frequently reported condition associated with use of antiretroviral (ARV) drugs. Poly-L-lactic acid (PLLA) acid has been used to correct facial lipoatrophy in people with HIV since 2004 both in Europe and the United States. The objective of this study was to establish, in real life conditions ...
O'Neil G Ab GA Fresh Start Recovery Programme, - - 2014
It has been reported that the average overdose mortality rate for patients detoxing from methadone in the UK, is 46pt/1000py in the first month following detox (Cornish et al, 2010). This highlights the need to provide safe and effective detox services alongside the provision and high quality sustained release naltrexone ...
Touzeau D D Clinique Liberte, - - 2014
this study assesses the effectiveness of buprenorphine/naloxone combination in reducing intravenous (IV) misuse of buprenorphine in opioid-dependent patients. 158 patients >= 18 years, who misused buprenorphine intravenously >= 4 times/week and treated for opioid dependency with buprenorphine ( >= 2 mg/day dose) for >= 3 months were included in a multicenter, ...
Sarnoff Deborah S - - 2014
Cervicofacial aging is often characterized by a combination of skin and subcutaneous tissue laxity, midfacial deflation, an accumulation of excess submental fat, an obtuse cervicomental angle, jowls, and rhytides of the face and neck. Traditional treatment, and the "gold standard" against which other treatments are compared, is a facelift.<BR /> ...
Ottens Thomas H TH From the Department of Anesthesiology (T.H.O., J.M.D., A.-M.C.S., C.J.K.), Department of Epidemiology, Julius Center for Epidemiology and Primary Care (L.M.P.), Department of Cardiothoracic Surgery (M.P.B.), and Intensive Care Medicine (D.v.D.), University Medical Center, Utrecht, The Netherlands; Department of Anesthesiology, Isala Clinics, Zwolle, The Netherlands (A.P.N.); Department of Anesthesiology, Erasmus University Medical Center, Rotterdam, The Netherlands (W.J.d.G.); and Department of Cardiology, University Medical, Utrecht, The Netherlands - - 2014
Cardiac surgery can be complicated by postoperative cognitive decline (POCD), which is characterized by impaired memory function and intellectual ability. The systemic inflammatory response that is induced by major surgery and cardiopulmonary bypass may play an important role in the etiology of POCD. Prophylactic corticosteroids to attenuate the inflammatory response ...
Doan Quynh - - 2014
ABSTRACTIntroduction:Emergency department (ED) crowding is a significant problem in Canada and has been associated with decreased quality of care in general and pediatric emergency departments (PEDs). Although boarding of admitted patients in the ED is the main contributor to adult ED overcrowding, factors involved in PED crowding may be different. ...
Al-Hindi Adel A AA Planning & Development Department, Maternity and Children's Hospital, PO Box 4230, Buraidah 51491, Al-Qassim, Kingdom of Saudi Arabia. E-mail. - - 2014
To evaluate the effectiveness of implementation of the pediatric Canadian Triage and Acuity Scale (Ped-CTAS) for children visiting the pediatric emergency department (ED). This cross-sectional study evaluated all children presented to the ED during a 9-day period in March 2010. The Ped-CTAS triage system was used. Triage performance was analyzed ...
Uzun Alper A Clinic of Cardiovascular Surgery, Ankara Education and Research Hospital, Ankara-Turkey. - - 2014
Prosthetic vascular access is the other choice when the superficial venous system is inadequate to perform a simple radio-cephalic and brachio-cephalic fistula. This paper reports the outcomes of a prospective cohort study of 54 patients who underwent either saphenous vein (SVI Group, n=29) or PTFE graft (PTFE Group, n=25) interposition ...
Leppert Kimberly K Kimberly Leppert, MSN, RN, CNOR, ONC, Graduate Student, Seattle Pacific University, Seattle, - - 2014
At a Pacific Northwest hospital completing more than 500 total joint procedures annually, operating room and unit orthopaedic nurses questioned the notable differences in the drain and transfusion practices of orthopaedic surgeons performing total hip arthroplasty (THA). The nurses also questioned the hematocrit outcomes of the primary THA patients receiving ...
Ahmed Asim A Department of Pulmonology, Fatima Memorial Hospital, - - 2014
To assess the utility of liver function tests (LFTs) for early recognition and prediction of severity of Dengue fever in hospitalized patients. An analytical study. Services Institute of Medical Science and Fatima Memorial Hospital, Lahore, from September - December 2010. Admitted cases of Dengue fever were divided into 3 groups; ...
Karabacak Osman Raif OR Department of Urology, Ministry of Health Ankara Diskapi Yildirim Beyazit Education and Research Hospital, Ankara, - - 2014
To evaluate the efficacy of subureteral injection types in patients with middle- to high-grade vesicoureteral reflux (VUR). Between June 1999 and September 2010, subureteral dextranomer was applied at our clinic to 149 patients (214 refluxing ureters) with grades II, III, and IV VUR. Group 1 consisted of 54 patients (80 ...
Siablis Dimitris D Interventional Radiology Department, Patras University Hospital, Patras, - - 2014
This study sought to report the results of a prospective randomized controlled trial comparing paclitaxel-coated balloons (PCB) versus drug-eluting stents (DES) in long infrapopliteal lesions. DES have an established role in the treatment of short infrapopliteal lesions, whereas there is increasing evidence for the use of PCB in longer below-the-knee ...
Deng Xiaoqian X Xiaoqian Deng, MD, Resident, Department of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, - - 2014
Objective : We aimed to compare the anesthetic characteristics between total intravenous anesthesia (TIVA) using propofol-remifentanil with target control infusion (TCI) and volatile induction and maintenance anesthesia (VIMA) using sevoflurane and sufentanyl for patients undergoing laparoscopic cholecystectomy. A total of 120 patients undergoing laparoscopic cholecystectomy were randomly assigned to two ...
Zhang Zhen Z Zhen Zhang, Department of Surgery, Mengyin People's Hospital, Shandong Province, 276200, P. R. - - 2014
To compare the clinical efficacy and surgical effects of the anterior low small incision and the traditional incision in the treatments of thyroid adenomas. Eighty cases of thyroid adenoma patients were randomly divided into a control group and an experimental group. Forty patients in the control group received the traditional ...
Saracino A A Basilicata Referral Center for Transplantation Hospital of Matera, Matera, Italy. Electronic address: - - 2014
The single-nucleotide polymorphisms (SNPs) of the Multidrug resistance 1 (MDR1) gene have been associated with changes in the pharmacokinetics of cyclosporine (CsA) and tacrolimus (FK506). Our aim was investigate the influence of MDR1 SNPs on long-term graft survival in a population of kidney transplant recipients. We retrospectively analyzed 154 patients; ...
Quaglia M M Nephrology and Transplant Unit, Department of Translational Medicine, "Maggiore della Carità" University Hospital and Interdisciplinary Research Center Autoimmune Disease (IRCAD), "A. Avogadro" University, Novara, Italy. Electronic address: - - 2014
The Immuknow assay (IKA; Cylex) is a T-cell immune function assay that evaluates immunoreactivity in immunocompromised patients. The aim of this study was to analyze IKA values in a cohort of kidney transplantation (KT) recipients to investigate correlations between single-time point low IKA values and their trend over time with ...
Agaçayak K S KS Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Dicle University, Diyarbakir, - - 2014
Background: Bisphosphonate (BP)-related osteonecrosis of the jaw (BRONJ) disease is rare, but there are serious side-effects of BP therapy in patients. In some patients, surgery is needed and could not be cured. A standard test is not available showing the risk of jaw osteonecrosis in routine use. The measurement of ...
Valentín Isa I - - 2014
This study was intended to determine the incidence rate of warfarin-related adverse events (e.g., bleeding) in Puerto Ricans and whether a genetic association between warfarin pharmacogenes and any of these adverse events was observed over the initiation period (i.e., the first 90 days of therapy). We conducted an observational, retrospective ...
Kim Tae Yeob TY 0000-0001-7978-5303 Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University, Guri, - - 2014
This study aimed to assess and compare sarcopenia with other prognostic factors for predicting long-term mortality in cirrhotic patients with ascites. Clinical data of 65 among 89 patients with measurement of all parameters were consecutively collected. Sarcopenia was evaluated as right psoas muscle thickness measurement divided by height (PMTH) (mm/m). ...
Kim Wonki W 0000-0001-7197-2366 Department of Neurosurgery, Seoul National University College of Medicine, Seoul, - - 2014
We investigated the effect of propofol and fentanyl on microelectrode recording (MER) and its clinical applicability during subthalamic nucleus (STN) deep brain stimulation (DBS) surgery. We analyzed 8 patients with Parkinson's disease, underwent bilateral STN DBS with MER. Their left sides were done under awake and then their right sides ...
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