Search Results
Results 501 - 550 of 11589
< 6 7 8 9 10 11 12 13 14 15 16 >
Scheid Christof C University Hospital of Cologne, Cologne, - - 2014
Approximately 15% of multiple myeloma (MM) patients exhibit a t(4;14) translocation, which often results in constitutive activation of the receptor tyrosine kinase (RTK) fibroblast growth factor receptor 3 (FGFR3). This study evaluated the efficacy and safety of dovitinib, an RTK inhibitor with in vitro inhibitory activity against FGFR, in patients ...
Nishina Naoshi N Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine , Tokyo , - - 2014
Objectives. To investigate the clinical effectiveness of tocilizumab (TCZ), a monoclonal antibody against the interleukin-6 receptor, in preventing relapse in patients with adult-onset Still's disease (AOSD). Methods. This retrospective study included clinical data from 40 patients who underwent regular follow-up at our institution in June 2013. Among these patients, 10 ...
Mohaddes Maziar M Department of Orthopedics , Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg; the Swedish Hip Arthroplasty Register, Gothenburg , - - 2014
Background and purpose - The use of trabecular metal (TM) cups in revision surgery has increased worldwide during the last decade. Since the introduction of the TM cup in Sweden in 2006, this design has gradually replaced other uncemented designs used in Sweden. According to data from the Swedish Hip ...
Abdel-Ghaffar Hala Saad HS Assisstant professor in Anesthesia and intensive care department, faculty of medicine, Assiut university, - - 2014
To evaluate the risk of peri-operative bleeding and re-intervention with peritonsillar lornoxicam infiltration in pediatric tonsillectomy. Prospective, randomized, double-blinded, placebo-controlled, split-body study. university hospital. 68 patients (7-15 y), ASA I-II scheduled for tonsillectomy divided into two groups (n=34) to receive bilateral peritonsillar saline infiltration (Placebo group), or peritonsillar saline infiltration ...
Mastoris Ioannis I The Zena and Michael A. Wiener Cardiovascular Institute, the Icahn School of Medicine at Mount Sinai, New York, New - - 2014
The first transcatheter aortisc valve replacement (TAVR) was performed in 2002, and has been proven beneficial in inoperable and high-risk patients for open heart surgery. Stroke occurrence after TAVR, both periprocedure and at follow-up, has not been well described. We sought to review incidence, pathophysiology, predictors, prognosis, and current preventive ...
Saliba Issam I Division of Otolaryngology-Head and Neck Surgery, Montreal University Hospital Center (CHUM), University of Montreal, Montreal, Quebec, Canada - - 2014
To compare the effectiveness of the endolymphatic duct blockage (EDB) and the endolymphatic sac decompression (ESD) to control Ménière's disease symptoms and to evaluate their effect on hearing level. Prospective nonblinded randomized study. Tertiary medical center. Fifty-seven patients affected by a refractory Ménière's disease were included out of which 22 ...
Gursu Sarper S Baltalimani Metin Sabanci Bone and Joint Diseases Hospital, Istanbul, Turkey - - 2014
Severe equinovarus foot deformity in adults is a challenging problem. Conservative treatment rarely is effective, and operative options are limited. The aim of this study was to evaluate the results of talectomy and tibiocalcaneal arthrodesis with intramedullary nail fixation for the treatment of severe equinovarus deformity in adults. Twelve patients ...
Silva M G Amila N MG Department of Orthopaedic Surgery, Singapore General Hospital, Singapore - - 2014
The prevalence of tibialis posterior tendon dysfunction (PTTD) is estimated to be as high as 3% to 4% in Western populations, and it is one of the most commonly misdiagnosed conditions of the foot and ankle. Clinical and radiological outcomes were assessed in grade IIB PTTD treated with a medializing ...
Subbu Raj R Institute of Sport Exercise and Health, University College London Hospitals, London, UK - - 2014
Avulsion of the proximal hamstring origin is well documented, and surgical treatment is advocated for complete avulsions. To compare the return to preinjury level of sport and the complexity of surgery in athletes undergoing surgical intervention for complete proximal hamstring avulsions within 6 weeks, 6 months, and after 6 months ...
Calvo Rafael R Orthopaedic Surgery Department, Clínica Alemana Santiago, Santiago, - - 2014
The treatment of anterior cruciate ligament (ACL) injuries in skeletally immature patients is controversial. Current evidence supports the view that surgical techniques restore knee stability and prevent progressive articular damage. However, most of the studies on this topic are small case series or they have short- or medium-term follow-up times. ...
Müller-Stich Beat P BP *Department of General, Visceral and Transplantation Surgery †Institute of Medical Biometry and Informatics ‡Study Center of the German Surgical Society (SDGC) §Department of Internal Medicine I and Clinical Chemistry, University of Heidelberg, Heidelberg, Germany ¶Department of Surgery, Kantonsspital St Gallen, Rorschacher Strasse 95, CH-9007 St Gallen, - - 2014
To compare surgical versus medical treatment of type 2 diabetes mellitus (T2DM) remission and comorbidities in patients with a body mass index (BMI) less than 35 kg/m. Obesity surgery can achieve remission of T2DM and its comorbidities. Metabolic surgery has been proposed as a treatment option for diabetic patients with ...
Tornero Eduard E Department of Traumatology and Orthopaedic Surgery. Hospital Clínic of - - 2014
The aim of this study was to compare the prosthetic joint infection (PJI) rate after total joint arthroplasty in two consecutive periods with different antibiotic prophylaxis: cefuroxime versus cefuroxime plus teicoplanin. We retrospectively reviewed 1897 patients who underwent THA or TKA between March 2010 and February 2013. From March 2010 ...
Walls Raymond J RJ Department of Orthopaedic Surgery, James Connolly Memorial Hospital, Blanchardstown, Dublin, Ireland; Department of Orthopaedic Surgery, Cappagh National Orthopaedic Hospital, Finglas, Dublin, Ireland. Electronic address: - - 2014
A tourniquet may potentiate rare and devastating arterial complications after total knee replacement (TKR) in patients with peripheral vascular disease (PVD). Most prior studies that evaluated peripheral arterial blood flow primarily used the ankle-brachial index (ABI). We assessed the prevalence and risk factors for PVD in a cohort undergoing TKR. ...
Han Jinu J Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, - - 2014
To investigate long-term strabismus surgical outcomes and visual prognosis in preadolescent ocular myasthenia gravis (OMG). The medical records of all patients with preadolescent onset OMG who underwent strabismus surgery were reviewed. Thirteen patients met the study inclusion criteria. The main outcomes, including ocular alignment, number of surgeries, and visual acuity ...
Koyama Yutaka Y Department of Cardiovascular Surgery, Toyohashi Heart Center, 21-1 Gobutori, Oyama-cho, Toyohashi, Aichi, 441-8530, Japan, - - 2014
As transcatheter aortic valve implantation (TAVI) may become a potential treatment for high-risk patients with aortic stenosis (AS), evaluation of outcomes after open aortic valve replacement (AVR) in elderly patients is warranted. We documented early and late outcomes after isolated AVR in octogenarians compared with younger age groups. From January ...
Matsuyama Hideyasu H Department of Urology, Graduate School of Medicine, Yamaguchi University, Ube, Yamaguchi, - - 2014
To determine the feasibility of vesicourethral anastomosis using running suture during retropubic radical prostatectomy and to compare the surgical outcomes of vesicourethral anastomosis using running suture with those of the standard interrupted suture technique. A total of 60 patients undergoing radical prostatectomy from 2010 to 2012 at the Yamaguchi University ...
Gilard Martine - - 2014
The currently recommended duration of dual antiplatelet therapy (DAPT) in drug-eluting stent (DES) recipients is 12 months, to reduce the risk of late stent thrombosis, particularly in acute coronary syndrome. It was hypothesized that antiplatelet treatment with DAPT for 6 versus may be non-inferior to DAPT for 24 months in ...
Perkins Gavin D GD Warwick Clinical Trials Unit, University of Warwick, Coventry, UK; Heart of England NHS Foundation Trust, Birmingham, UK. Electronic address: - - 2014
Mechanical chest compression devices have the potential to help maintain high-quality cardiopulmonary resuscitation (CPR), but despite their increasing use, little evidence exists for their effectiveness. We aimed to study whether the introduction of LUCAS-2 mechanical CPR into front-line emergency response vehicles would improve survival from out-of-hospital cardiac arrest. The pre-hospital ...
Yoshimura Shinichiro S Department of Anesthesiology and Medical Crisis Management, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, Japan, - - 2014
It is recommended that the period of fasting before elective surgery should be shortened to facilitate a rapid recovery by preventing catabolism. We examined the effects of a short period of fasting on metabolism by performing indirect calorimetry (IC) under general anesthesia. A prospective observational study involving 26 consecutive patients ...
Al-Moraissi E A EA Department of Oral and Maxillofacial Surgery, Faculty of Oral and Dental Medicine, Cairo University, Cairo, Egypt; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Thamar University, Thamar, Yemen. Electronic address: - - 2014
The aim of this study was to compare the clinical and radiological outcomes of mandibular angle fractures (MAFs) managed with three-dimensional (3D) miniplates and standard miniplates (according to Champy's principles). A prospective, randomized, controlled clinical study was carried out on 20 patients with MAFs, divided into two groups. Group A ...
Srinivasa Sanket S Department of Surgery, South Auckland Clinical School, Middlemore Hospital, University of Auckland, Auckland, New Zealand. Electronic address: - - 2014
Introduction: Goal-Directed Fluid Therapy (GDFT) has been previously shown to decrease complications and hospital length of stay in major colorectal surgery but the data are not specific to rectal surgery and may be potentially outdated. This study investigated whether GDFT provides clinical benefits in patients undergoing major elective rectal surgery. ...
Bunnell Avianne P AP University of Central Florida College of Medicine, Orlando - - 2014
Endovenous thermal ablation has emerged as an alternative therapy for the treatment of chronic superficial venous insufficiency (CVI) of the lower extremities. Recanalization, or anatomic failure, of a vein following endovenous radiofrequency ablation (RFA) has been described, albeit an infrequent occurrence. This study was performed to demonstrate risk factors associated ...
Fitridge Robert A RA Discipline of Surgery, The University of Adelaide, The Queen Elizabeth Hospital, 28 Woodville Road, Woodville South, SA 5011, Australia. Electronic address: - - 2014
To review trends in patient selection and early death rate for patients undergoing elective endovascular repair of infrarenal abdominal aortic aneurysms (EVAR) in three countries. For this study, audit data from 4163 patients who had undergone elective infrarenal EVAR were amalgamated. The data originated from Australia, Canada (Ontario), and England ...
Chaudhry Tahseen T Royal Orthopaedic Hospital, Bristol Road, Birmingham, UK. Electronic address: - - 2014
To report the results of a technique of soft tissue stabilization for palmar midcarpal instability using a palmaris longus graft. In patients' symptomatic wrists with palmar midcarpal instability that had failed conservative management, we used a dorsal approach and stabilized the hamate and triquetrum by reconstructing the dorsal triquetrohamate ligament. ...
Martín Giral E E Departamento de Glaucoma, Servicio de Oftalmología, Hospital Universitario de Fuenlabrada, Madrid, España. Electronic address: - - 2014
The objective of this study is to compare the efficacy and safety of bevacizumab versus mitomycin C as an adjuvant anti-scarring agent in Trabeculectomy. A prospective, comparative, non-randomized, interventional study was conducted on a case series. A total of 49 eyes of 45 patients with uncontrolled glaucoma were recruited: 22 ...
Cano-Ortiz A A Sección Córnea, Superficie Ocular Y Refractiva, Hospital La Arruzafa, Córdoba, - - 2014
To evaluate the effectiveness of deep anterior lamellar keratoplasty (DALK) using Melles technique (technique B) in patients with advanced keratoconus versus a classic technique, penetrating keratoplasty (technique A). Retrospective descriptive comparative study between technique A and technique B in homogeneous groups. Best corrected visual acuity (Snellen test decimal scale) was ...
Fariña R R Maxillofacial Surgery, Hospital del Salvador, Santiago, Chile; Maxillofacial Surgery, Hospital San Borja Arriarán, Santiago, Chile; Oral and Maxillofacial Surgery, Universidad de Chile, Santiago, Chile. Electronic address: - - 2014
The purpose of this study was to measure the changes in facial, occlusal, and skeletal relationships in patients with active unilateral condylar hyperplasia whose sole treatment was a low condylectomy. A retrospective observational descriptive study was conducted. All patients had undergone a low condylectomy as the sole or initial surgical ...
Jirschele K K Division of Urogynecology, University of Chicago/NorthShore University HealthSystem, 9650 Gross Point Road, Suite 3900, Skokie, IL, 60076, USA, - - 2014
Hysterectomy is often part of pelvic organ prolapse repair. However, this may offer no benefit when compared to uterine preservation. We aimed to prospectively evaluate a minimally invasive bilateral sacrospinous hysteropexy using polypropylene mesh. We hypothesized that anatomic success and patient satisfaction can be achieved with this technique. Women with ...
Wilczynski M M Department of Cardiac Surgery, Medical University of Silesia, Katowice, Poland - - - 2014
This randomized prospective clinical trial aimed to evaluate safety and efficacy of preoperative use of eptifibatide in high risk patients with non--ST--segment elevation acute coronary syndrome (NSTE--ACS), requiring urgent coronary artery bypass graft surgery (CABG). A total of 140 patients with NSTE--ACS eligible for urgent surgical revascularization received either eptifibatide ...
Buldu Ibrahım I Department of Urology, School of Medicine, University of Mevlana, Konya, Turkey, - - 2014
To investigate whether aging affects surgical outcomes by comparing the results of two patient groups undergoing PNL: those over 60 and those under 60. A retrospective screen was made for patients undergoing conventional PNL surgery for renal stones performed in two separate centers between 2010 and 2013. 520 patients included ...
Suzuki Satoshi S Division of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe, Hyogo, Japan, - - 2014
Our purpose was to evaluate the perioperative safety of laparoscopic-assisted distal gastrectomy (LADG) in elderly patients with clinical stage I gastric cancer. From 527 consecutive patients who underwent distal gastrectomy for gastric cancer from 2000 to 2011, 38 elderly patients (aged 75 years or older) with clinical stage I disease who ...
Czarnywojtek Agata - - 2014
INTRODUCTION Treatment of Amiodarone-Induced Thyrotoxicosis (AIT) is still a difficult problem; it requires the cooperation of both endocrinologists and cardiologists. Unfortunately, even today AIT is related to increased mortality.  OBJECTIVES The aim of this study was to assess and compare the efficacy of radioidine (RAI) therapy for type II AIT in patients ...
Karefylakis Christos C Division of Internal Medicine, Department of Endocrinology, Örebro University Hospital, 70185, Örebro, Sweden, - - 2014
Bariatric surgery has gained wide acceptance as treatment for severe obesity and is associated with decreased overall mortality. The aims of this study were to evaluate the prevalence of anemia long term after Roux-en-Y gastric bypass (RYGB) and to search for factors predicting anemia. All 745 patients who underwent RYGB ...
Sczepaniak John P JP Sczepaniak Health and Medical Enterprises, 6871 Eberhart St., San Diego, CA, 92115, - - 2014
Weight loss after bariatric surgery is commonly reported as either a percentage of initial body weight (%IBW) or 100 % minus %IBW which is a percentage of total weight loss (%TWL). These are basically equivalent expressions. Weight loss is also reported as %EWL or as a percentage of excess body mass ...
Choi B J BJ Lee Eye Clinic, Pusan, Republic of - - 2014
PurposeComparison of visual acuity, refractive, and wavefront outcomes associated with optimized prolate ablation (OPA) and optical path difference custom aspheric treatment (OPDCAT) algorithms for correction of myopia exceeding 8 diopters (D).Patients and MethodsPatients were randomly assigned to have photorefractive keratectomy (PRK) with OPA (n=32) or OPDCAT (n=21) algorithms. Visual acuity, ...
Choi G J GJ Department of Anaesthesiology and Pain Medicine, Chung-Ang University College of Medicine, Seoul, - - 2014
This study aimed to compare emergence agitation following sevoflurane and desflurane anaesthesia in adults undergoing orthognathic surgery. The hypothesis was that there might be a difference in the incidence of emergence agitation following sevoflurane and desflurane anaesthesia considering the difference in blood solubility and speed of recovery between the two. ...
Schweren L J S LJ Department of Psychiatry, University Medical Center Groningen, University of Groningen, Huispostcode CC10, 9700, VB, Groningen, The Netherlands, - - 2014
Meta-analyses suggest normalizing effects of methylphenidate on structural fronto-striatal abnormalities in patients with attention-deficit/hyperactivity disorder (ADHD). A subgroup of patients receives atypical antipsychotics concurrent with methylphenidate. Long-term safety and efficacy of combined treatment are unknown. The current study provides an initial investigation of structural brain correlates of combined methylphenidate and ...
Jovanovic Dijana B DB Faculty of Medicine, University of Belgrade , Belgrade , Serbia - - 2014
Abstract Background/Aim: Besides peritonitis, the most common complication, indicators of chronic inflammation are also present in patients treated by peritoneal dialysis. The aim of this study was to analyze the predictive value of inflammatory parameters on mortality of continuous ambulatory peritoneal dialysis (CAPD) patients. Methods: Eighty-seven patients (57 males), aged ...
Petrov George G Department of Internal Medicine/Cardiology, German Heart Institute Berlin, Augustenburger Platz 1, 13353, Berlin, - - 2014
The effectiveness of stress cardiac magnetic resonance (CMR) as a gatekeeper for coronary angiography (CA) has been established. Level five HTA studies according to the hierarchical model of diagnostic test evaluation are not available. This cohort study included 1,158 consecutive patients (mean age 63 ± 11 years, 42 % women) presenting at our institution ...
Hsu C-I CI Graduate Institute of Clinical Pharmacy, College of Medicine, National Taiwan University, Taipei, - - 2014
The study aimed to compare the adherence and persistence among newly diagnosed hypertensive patients using fixed-dose (FDC) and free combinations (FC) of angiotensin receptor blocker (ARB)/thiazide diuretic using Taiwan's National Health Insurance Research Database. General linear regression and Kaplan-Meier analyses were used to estimate the impact of FDC on adherence ...
Jang Young-Eun YE Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 110-744, South - - 2014
Dexmedetomidine is a useful anesthetic adjuvant for general anesthesia. We determined whether preoperative dexmedetomidine administration could reduce the half maximal effective concentration (EC50) of propofol for successful i-gel insertion without muscle relaxants. Thirty-seven patients were randomly allocated to one of two groups. In the dexmedetomidine group (n = 19), dexmedetomidine (1 µg/kg) was ...
Melberg Tor T Department of Cardiology, Stavanger University Hospital, Stavanger, Norway - - 2014
Early discharge after uncomplicated primary percutaneous coronary intervention (PPCI) is common but the evidence supporting this practice is lacking. We therefore performed a randomized, prospective trial comparing outcomes in low risk PPCI randomized to early discharge or usual care. Over a two years period, all surviving PPCI patients at a ...
Tzoulis Ploutarchos P Centre for Neuroendocrinology, Royal Free Campus, University College Medical School, London, - - 2014
Hyponatraemia is associated with significant morbidity and mortality. The objectives of this study were to evaluate the investigation and management of hyponatraemia and to assess the use of different therapeutic modalities and their effectiveness in routine practice. This multicentre, retrospective, observational study was conducted at three acute NHS Trusts in ...
Hsu Yao-Chun YC Graduate Institute of Clinical Medicine, China Medical University, Taichung, Taiwan Department of Internal Medicine, E-Da Hospital, Kaohsiung, Taiwan Center for Database Research, E-Da Hospital, Kaohsiung, Taiwan School of Medicine, I-Shou University, Kaohsiung, - - 2014
To elucidate the association between antiviral therapy and extrahepatic outcomes in individuals infected with HCV. This nationwide cohort study screened 293 480 Taiwanese residents with HCV infection and excluded those with substantial comorbidity. A total of 12 384 eligible patients who had received pegylated interferon plus ribavirin between 1 October 2003 and ...
Mori Hirohito H Hirohito Mori, Hideki Kobara, Shintaro Fujihara, Noriko Nishiyama, Tae Matsunaga, Maki Ayaki, Tatsuo Yachida, Joji Tani, Hisaaki Miyoshi, Asahiro Morishita, Tsutomu Masaki, Departments of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa 761-0793, - - 2014
To investigate the effects of gastric lavage with 2000 mL of saline in laparoscopic and endoscopic cooperative surgery. Twenty two patients who were diagnosed with a gastric gastrointestinal stromal tumor were enrolled. In former term, irrigations of the stomach were conducted whenever it was necessary, not systematically (Non systemic lavage ...
Dietrich Christoph G CG Christoph G Dietrich, Manuela Alavi, Department of Medicine, Bethlehem Hospital, Teaching Hospital of Aachen University RWTH, 52222 Stolberg, Rhineland, - - 2014
To investigate the effect of Lactobacillus-containing commercially available probiotic formulations in Germany during antibiotic treatment with an analysis of cost-efficiency. In an observational study, we analyzed the frequency of bowel movements from 258 patients with infections in a primary care hospital in western Germany; 107 of the patients were offered ...
Jung Yoon Suk YS Yoon Suk Jung, Dong Il Park, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul 110-746, South - - 2014
To compare efficacy, patient compliance, acceptability, satisfaction, safety, and adenoma detection rate of sodium phosphate tablets (NaP, CLICOLON(TM)) to a standard 4 L polyethylene glycol (PEG) solution for bowel cleansing for adults undergoing colonoscopy. In this multicenter, randomized, prospective, investigator-blind study, the relatively young (19-60 years) healthy outpatients without comorbidity ...
Jie Hong-Ying HY Hong-Ying Jie, Ji-Lu Ye, Department of Intensive Care Unit, Taizhou People's Hospital, Medical School of Nantong University, Taizhou 225300, Jiangsu Province, - - 2014
To investigate the effect of perioperative restricted fluid therapy on circulating CD4(+)/CD8(+) T lymphocyte ratio, percentage of regulatory T cells (Treg) and postoperative complications in patients with colorectal cancer. A total of 185 patients met the inclusion criteria and were included in the randomized clinical trial. These patients were divided ...
Lee Junhyun J Department of Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of - - 2014
Background: Radical gastrectomy for gastric cancer is one of the most invasive procedures in gastrointestinal surgery. A few studies have found that an enhanced recovery after surgery (ERAS) protocol is useful in radical gastrectomy. The aim of this study was to evaluate the appropriate indication and feasibility of an ERAS ...
Rodriguez-Merchan E Carlos EC aDepartment of Orthopaedic Surgery bDepartment of Rehabilitation and Physical Medicine cDepartment of Haematology, La Paz University Hospital, Madrid, - - 2014
The purpose of this study is to describe the results of arthroscopic ankle debridement (AAD) with the aim of determining whether it is possible to avoid or delay ankle fusion or total ankle replacement for advanced haemophilic arthropathy of the ankle in young patients. In a 12-year period (2000-2011), 24 ...
< 6 7 8 9 10 11 12 13 14 15 16 >