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Yamamoto Naomune N Department of Medicine, Tokyo Women's Medical University, Medical Center East , Tokyo , Japan - - 2014
We evaluated their circadian rhythms using data from electrocardiographic records and examined the change in circadian period related to normal RR intervals for astronauts who completed a long-term (≥6-month) mission in space. The examinees were seven astronauts, five men and two women, from 2009 to 2010. Their mean ± SD age was ...
Phan Kevin K The Collaborative Research (CORE) Group, Macquarie University, Sydney, Australia Westmead Hospital, Sydney Medical School, University of Sydney, Sydney, - - 2014
Simplified maze procedures involving radiofrequency, cryoenergy and microwave energy sources have been increasingly utilized for surgical treatment of atrial fibrillation as an alternative to the traditional cut-and-sew approach. In the absence of direct comparisons, a Bayesian network meta-analysis is another alternative to assess the relative effect of different treatments, using ...
Raj Kishan K Department of Neurology, All India Institute of Medical Sciences, New Delhi, - - 2014
India is a subtropical country with clear seasonal variations in weather conditions. Seasonal and circadian variation in occurrence of subtypes of cerebrovascular disease has been of interest in several studies from different countries and climate zones, but discrepant results have made the conclusions unclear. The aim of the present study ...
Goto Yoshikazu - - 2014
IntroductionThe prognostic significance of conversion from non-shockable to shockable rhythms in patients with initial non-shockable rhythms who experience out-of-hospital cardiac arrest (OHCA) remains unclear. We hypothesized that the neurological outcomes in those patients would improve with subsequent shock delivery following conversion to shockable rhythms, and that the time from initiation ...
Ullah Waqas W Cardiovascular Biomedical Research Unit, St Bartholomew's Hospital, Barts Health NHS Trust, London, - - 2014
Pre-clinical work suggests factors including catheter orientation and contact consistency during individual radiofrequency ablations influence lesion size. Our aim was to investigate factors affecting catheter contact in the left atrium (LA) and their effects on ablation. 2,298 8-second static LA mapping points were studied in 30 patients undergoing ablation for ...
Mehta Jimish M JM Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, - - 2014
(See the commentary by Van Schooneveld and Rupp, on pages 1100-1102 .) Objective. Although prior authorization and prospective audit with feedback are both effective antimicrobial stewardship program (ASP) strategies, the relative impact of these approaches remains unclear. We compared these core ASP strategies at an academic medical center. Design. Quasi-experimental study. Methods. We ...
Dickson Robert R From the *Good Shepherd Health System, Longview, TX; †University of Arkansas School of Medicine Department of Emergency Medicine, Little Rock, AR; and ‡Scott and White Department of Emergency Medicine, Temple, - - 2014
The objective of our study was to evaluate the effect of the STOP STEMI© medical application on door-to-balloon (D2B) time in patients arriving to our emergency department with an acute ST Elevation Myocardial Infarction (STEMI). STOP STEMI© is a novel medical application developed by physicians to improve the coordination and ...
McQuillan Annette A Cardiothoracic Unit, Great Ormond Street Hospital NHS Foundation Trust, London, - - 2014
We developed protocols to handover patients from day to hospital at night (H@N) teams. NHS paediatric specialist hospital. We observed four handover protocols (baseline, Phases 1, 2 and 3) over 2 years. A mixed-method study (observation, interviews, task analysis, prospective risk assessment, document and case note review) explored the impact of ...
Park Semi S Department of Internal Medicine, Graduate School, Yonsei University College of Medicine, Seoul, Korea. ; Center for Health Promotion, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, - - 2014
Obstructive jaundice in patients with hepatocellular carcinoma (HCC) is uncommon (0.5-13%). Unlike other causes of obstructive jaundice, the role of endoscopic intervention in obstructive jaundice complicated by HCC has not been clearly defined. The aim of this study was to evaluate the clinical characteristics of obstructive jaundice caused by HCC ...
Thirumurthy Harsha H Department of Health Policy and Management, Gillings School of Global Public Health, University of North Carolina at Chapel Hill2Carolina Population Center, University of North Carolina at Chapel - - 2014
Novel strategies are needed to increase the uptake of voluntary medical male circumcision (VMMC) in sub-Saharan Africa and enhance the effectiveness of male circumcision as an HIV prevention strategy. To determine whether small economic incentives could increase circumcision prevalence by addressing reported economic barriers to VMMC and behavioral factors such ...
Zacherl Johannes J Department of General Surgery, Herz Jesu Krankenhaus, Vienna, Austria, - - 2014
Both long-term proton pump inhibitor (PPI) use and surgical fundoplication have potential drawbacks as treatments for chronic gastroesophageal reflux disease (GERD). This multi-center, prospective study evaluated the clinical experiences of 69 patients who received an alternative treatment: endoscopic anterior fundoplication with a video- and ultrasound-guided transoral surgical stapler. Patients with ...
Chia Daryl D Ministry of Health Holdings, - - 2014
Intra-procedural acute thrombosis (IPAT) is a complication of endovascular procedures. We aim to identify risk factors for IPAT and compare the outcomes of patients with or without IPAT. Paired T test and χ(2) test were used to identify risk factors and short-term outcomes. Kaplan-Meier survival analysis was used for mid-term ...
Michalek Carina C Geriatric Clinic and Center for Geriatric Medicine, Knappschafts-Krankenhaus, Kliniken Essen-Mitte, Teaching Hospital of the University Duisburg-Essen, Am Deimelsberg 34a, 45276, Essen, - - 2014
The feasibility of applying the Fit fOR The Aged (FORTA) list, a drug classification combining positive and negative labeling of drugs, should be studied in geriatric patients and medication quality and clinical endpoints measured. FORTA labels range from A (indispensable), B (beneficial), C (questionable) to D (avoid). A prospective randomized ...
Brogan Kit K Department of Orthopaedics, Western Sussex NHS trust, Worthing Hospital, Worthing, BN11 2DH, UK, - - 2014
There is growing evidence supporting minimally invasive surgical (MIS) techniques for correction of symptomatic hallux valgus. The aim of this study was to present a hybrid third-generation technique and assess the safety and efficacy from the first 45 procedures. Forty-five consecutive feet underwent a third-generation MIS distal chevron osteotomy with ...
Lee Hannah H Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-Gu, Seoul, 110-744, Korea, - - 2014
During the immediate postoperative period after liver transplantation (LT), postoperative bleeding and vascular complications (stenosis, thrombosis) are the two most common complications that require therapeutic decisions. Doppler ultrasound (DUS) is the established method for screening vascular patency after LT during the immediate postoperative period. The objective of our study was ...
Coscas Raphaël R Service de Chirurgie Vasculaire, Hôpital Universitaire Ambroise Paré, Assistance Publique-Hôpitaux de Paris (AP-HP), Boulogne-Billancourt, France; and Faculté de Médecine Paris-Ile de France-Ouest, UFR des sciences de la santé Simone Veil, Université Versailles Saint-Quentin en Yvelines, Montigny-le-Bretonneux, France. Electronic address: - - 2014
The radial approach is currently gaining popularity in the setting of coronary percutaneous transluminal angioplasty (PTA) because it decreases the incidence of vascular complications. This study reports our initial results with radial access for peripheral PTA. Between November 2011 and January 2014, we performed peripheral PTA in 526 patients. PTA ...
Sathanandam Shyam K SK The Heart Institute for Children, Advocate Hope Children's Hospital, Oak Lawn, Illinois; Department of Pediatrics, University of Tennessee Health Science Center, Memphis, - - 2014
The Sano modification of the Norwood operation is a well-established first step palliation for hypoplastic left heart syndrome (HLHS). Theoretically, the first point of resistance to pulmonary flow should be in the proximal Sano, generating high Doppler flow velocity. Paradoxically, however, some patients have low gradients in the proximal Sano ...
Chen Jerry Yongqiang JY Department of Orthopaedic Surgery, Singapore General Hospital, Outram Road, Academia Building Level 4, Singapore, 119228, Singapore, - - 2014
This study aimed to investigate the accuracy of pinless navigation (BrainLAB(®) VectorVision(®) Knee 2.5 Navigation System) as an intra-operative alignment guide in total knee arthroplasty (TKA). The authors hypothesized that pinless navigation would reduce the proportion of outliers in conventional TKA, without a significant increase in the duration of surgery. ...
Denham James W JW School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia. Electronic address: - - 2014
We investigated whether 18 months of androgen suppression plus radiotherapy, with or without 18 months of zoledronic acid, is more effective than 6 months of neoadjuvant androgen suppression plus radiotherapy with or without zoledronic acid. We did an open-label, randomised, 2 × 2 factorial trial in men with locally advanced prostate cancer ...
Binning Mandy J MJ Capital Health, Capital Institute for Neurosciences, Trenton and Pennington, New - - 2014
TREVO 2 showed the Trevo stent retriever to be more successful for revascularization than Merci for acute stroke intervention in patients treated within 8 hours of symptom onset. These results led to FDA approval of Trevo. To report the first post-market experience with Trevo since FDA approval at a single ...
van Bussel Erik M EM Department of Ophthalmology, University Medical Center Utrecht, Utrecht, the - - 2014
To systematically review the influence of the lag time between macula-off retinal detachment and surgical intervention on postoperative visual acuity as main outcome measure. Systematic review and meta-analysis of articles published from 1995 to October 2013 of patients with macula-off retinal detachment and treated with scleral buckling or pars plana ...
Naito Ryo R Department of Cardiology, Juntendo University Graduate School of Medicine, 2-1-1 Hongo Bunkyo-ku, Tokyo, 113-8421, - - 2014
Advances in percutaneous coronary intervention (PCI) have improved the outcomes of patients with coronary artery diseases. The advent of drug-eluting stents (DES) has dramatically reduced the rate of revascularization. The first-generation DES has yielded the main role of PCI to the second-generation DES; however, many patients had been implanted with ...
Stone Patrick A PA Department of Surgery, Robert C. Byrd Health Sciences Center, West Virginia University, Charleston, USA - - 2014
The purpose of our study was to determine outcomes of patients receiving the LifeStent (Bard Peripheral Vascular, Tempe, AZ) for femoropopliteal peripheral arterial disease in real-world academic practice outside the limitations of an industry supported trial. All patients from 2009 to 2012 at our institution who received a LifeStent during ...
Negredo Eugènia E Lluita contra la Sida Foundation, Germans Trias i Pujol University Hospital, Badalona, Spain Universitat Autònoma de Barcelona, Barcelona, - - 2014
Tenofovir has been associated with a decrease in bone mineral density (BMD). However, data on changes in BMD after discontinuing tenofovir are lacking. We performed a two-centre randomized pilot study in virologically suppressed HIV-infected patients receiving tenofovir with osteopenia/osteoporosis (OsteoTDF study, ClinicalTrials.gov number NCT 01153217). Fifty-four patients were randomly assigned ...
Vergallo Rocco R Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, - - 2014
Objectives: This study aimed to compare the effect of bivalirudin and unfractionated heparin (UFH) on residual thrombus burden assessed by frequency-domain optical coherence tomography (FD-OCT), and on angiographic indices of microvascular obstruction (MVO). Background: The efficacy of bivalirudin to inhibit thrombus formation inside the stent during percutaneous coronary interventions (PCI) ...
Inamura Noboru N Department of Pediatric Cardiology, and Pediatric Surgery, Osaka Medical Center and Research Institute for Maternal and Child Health, 840 Murodo-cho, Izumi, Osaka, 594-1101, Japan, - - 2014
The purpose of this study is to evaluate the outcome of our therapeutic strategy for antenatally diagnosed congenital diaphragmatic hernia (ADCDH). We treated 61 cases of ADCDH according to our strategy. Prostaglandin E1 was required to be maintained the patency of the ductus arteriosus (PDA) in 39 cases (Group I) ...
Meisenberg Barry B DeCesaris Cancer Center, Anne Arundel Medical Center, 2001 Medical Parkway, Annapolis, MD, 21401, USA, - - 2014
Febrile neutropenia (FN) remains a common and dangerous complication of cancer treatment. Guidelines from the Infectious Disease Society of America urge initiating antibiotics within 2 h of presentation. We reviewed our institution's performance to identify areas of needed improvement and to design performance improvement steps. FN management was deconstructed into discrete ...
Karlson Björn - - 2014
The period from the mid-1990s to the mid-2000s saw a rapid increase in long-term sick leave in Sweden, primarily due to mental illness and often related to job burnout. This led to an urge for effective treatment programs that could prevent the often long sick leaves. In 2010 we presented ...
Luley Claus C a Otto-von-Guericke University , Magdeburg , - - 2014
Objective: Mobile technology can improve lifestyle programs, but the monitoring techniques and carer feedback need to be optimized. To this end, we investigated the efficacy of telemonitoring physical activity and nutrition over 12 months in patients with metabolic syndrome in a randomized, parallel-group, open trial. Methods: Screening all over Germany ...
Tao Tao T Tao Tao, Yan-Qing Li, Department of Gastroenterology, Qilu Hospital of Shandong University, Jinan 250012, Shandong Province, - - 2014
To evaluate the effect of cholecystokinin (CCK) during extracorporeal shockwave lithotripsy (ESWL) in the clearance of common bile duct (CBD) stones in endoscopic retrograde cholangiopancreatography (ERCP). Between January 2007 and September 2012, patients with large CBD stones who were treated with ESWL and ERCP were identified retrospectively. Patients were randomized ...
Bariteau Jason T JT Department of Orthopedics, Emory University School of Medicine, Atlanta, GA, - - 2014
Charcot neuroarthropathy in the developed countries is primarily associated with diabetic neuropathy. This study investigated a series of patients with Charcot arthropathy associated with idiopathic peripheral neuropathy to evaluate the natural history in these patients and to evaluate the efficacy of a treatment protocol used for diabetic Charcot joints. The ...
Lampert Brent C BC Division of Cardiovascular Medicine, The Ohio State University Wexner Medical Center, Columbus, OH - - 2014
-Despite low risk of late rejection after heart transplant (HT), surveillance endomyocardial biopsies (EMB) are often continued for years. We assessed the cost-effectiveness of routine EMB beyond 12 months post-HT. -Markov model compared the following surveillance EMB strategies to baseline strategy of stopping EMB 12 months post-HT: 1.) q 4 ...
Kabata Paweł P Department of Surgical Oncology, Medical University of Gdańsk, Smoluchowskiego 17, 80-952, Gdańsk, Poland, - - 2014
Preoperative nutrition is beneficial for malnourished cancer patients. Yet, there is little evidence whether or not it should be given to nonmalnourished patients. The aim of this study was to assess the need to introduce preoperative nutritional support in patients without malnutrition at qualification for surgery. This was a prospective, ...
Petricevic Mate M Department of Cardiac Surgery, University of Zagreb School of Medicine, University Hospital Center Zagreb, Kispaticeva 12, 10000, Zagreb, Croatia, - - 2014
Individual variability in the response to aspirin, has been established by various platelet function assays, however, the clinical relevance of aspirin resistance (AR) in patients undergoing coronary artery bypass grafting (CABG) has to be evaluated. Our working group conducted a randomized controlled trial (NCT01159639) with the aim to assess impact ...
Keene David J DJ Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, - - 2014
Study Design Systematic review and meta-analysis. Objectives To compare early ankle movement versus ankle immobilization after surgery for ankle fracture on clinical and patient-reported outcomes. Background A significant proportion of patients undergoing surgery for ankle fracture experience postoperative complications and delayed return to function. The risks and benefits of movement ...
Quinn Charlene C CC University of Maryland School of Medicine, Baltimore, USA - - 2014
The purpose of this study was to assess effects of a mobile coaching system on glycated hemoglobin (HbA1c) levels in younger versus older patients over 1 year. Participants (n = 118) included adult patients with Type 2 diabetes cared for by community physicians. Intervention patients received mobile phone coaching and ...
Riddle Daniel L DL Departments of Physical Therapy, Virginia Commonwealth University, Richmond, Virginia, USA; Departments of Orthopaedic Surgery, Virginia Commonwealth University, Richmond, Virginia, - - 2014
Objective: We determined outcomes for patients classified as appropriate, inconclusive or inappropriate for total knee arthroplasty (TKA) using a modified version of a validated appropriateness algorithm. Outcome measurement was conceptualized as short-term post-operative change attributable primarily to surgery and rehabilitation (two-months) and as longer term post-operative change and recovery (one- ...
Zhang Yao-Jun YJ Thoraxcenter, Erasmus Medical Center, Rotterdam, the Netherlands; Nanjing First Hospital, Nanjing Medical University, Nanjing, - - 2014
The results of SYNTAX trial have been reported based on "corelab" calculated SS (cSS). It has been shown that reproducibility of SS is better among the core laboratory technicians than interventional cardiologists. Thus, the prognostic value and clinical implication of the "site" SYNTAX SS (sSS) remain unknown. The study sought to ...
Vignoletti Fabio F Department of Periodontology, Faculty of Dentistry, Complutense University of Madrid, Madrid, - - 2014
To evaluate histologically the healing of a xenogeneic collagen matrix (CM) used to augment the width of keratinized tissue around teeth. The gingiva on the buccal aspect of mandibular and maxillary premolars was surgically excised on 12 minipigs. After 1 month of plaque accumulation, the resulting defects were randomly treated by ...
Guo Qiang Q Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan Province, - - 2014
The best available evidence suggests that surgical intervention should be delayed where possible until four weeks after the onset of pancreatitis. Subgroups that may benefit from early or delayed intervention have not been identified. This study reviewed a prospective database with 223 patients of necrotizing pancreatitis who received intervention. A ...
Westin Gregory G GG Division of Vascular and Endovascular Surgery, New York University Medical Center, New York, New York, USA. Electronic address: - - 2014
To evaluate the efficacy of endovascular therapy for maintaining patency and preserving limbs among patients with failing infrapopliteal bypass grafts. We gathered data from a registry of catheter-based procedures for peripheral artery disease. Of 1554 arteriograms performed from 2006 to 2012, 30 patients had interventions for failing bypass vein grafts ...
Blyth Katrina M - - 2014
The impact of patient, surgical and rehabilitation factors on speech and swallowing in the acute phase for patients following tongue and/or floor of mouth cancer surgery has not been reported to date. This study reviewed functional outcomes over a 5 year period at an Australian tertiary hospital. Patient medical files ...
Shenoy Bhamy Hariprasad BH Jasti V Ramanamma Children's Eye Care Centre, LV Prasad Eye Institute, Hyderabad, - - 2014
To evaluate safety profile and surgical outcomes of a novel modification of loop myopexy with silicone band for myopic strabismus fixus (MSF). Retrospective interventional case series. A retrospective chart review of patients who underwent silicone band loop myopexy between January 2008 and December 2012 for MSF at a tertiary eye ...
Oh Jung Suk JS Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 505 Banpo-Dong, Seocho-Ku, Seoul, 137-040, Korea, - - 2014
To evaluate the effectiveness of a mechanical thrombolysis for thrombosed central venous port (CVP). A total of 38 patients (22 women and 16 men, median age of 55 years) were referred to our interventional unit for thrombosed implanted CVPs. The period between CVP implantation and the initial suspicion of mechanical complication ...
Cai Xiangran X Medical Imaging Center, First Affiliated Hospital, Jinan University, Guangzhou, China. Electronic address: - - 2014
To evaluate the impact of reduced-radiation dual-energy (DE) protocols using 320-detector row computed tomography on the differentiation of urinary calculus components. A total of 58 urinary calculi were placed into the same phantom and underwent DE scanning with 320-detector row computed tomography. Each calculus was scanned 4 times with the ...
Zhao Li-Na LN Department of Gastroenterology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong 510120, P.R. - - 2014
Somatostatin has been extensively studied for the prophylaxis of pancreatitis following endoscopic retrograde cholangiopancreatography (ERCP). However, the results remain controversial. The present retrospective cohort study aimed to investigate the efficacy of pre- and post-ERCP somatostatin administration in the prevention of post-ERCP pancreatitis (PEP). All ERCP procedures performed at one hospital ...
Forte Antonio Jorge AJ New Haven, Conn.; and São Paulo, Brazil From the Section of Plastic and Reconstructive Surgery, Yale School of Medicine; and the Department of Plastic Surgery, University of São - - 2014
Midface retrusion is the hallmark of the syndromic dysostoses (i.e., Crouzon and Apert). Lack of forward projection and/or structural deficiency could be responsible, but neither has been adequately assessed three-dimensionally. The authors examined both the cranial base/facial interface and the midface volume to provide an understanding of the etiopathogenesis of ...
Keir Amy A Division of Neonatology, Department of Paediatrics, Faculty of Medicine, University of Toronto, Toronto, Ontario, - - 2014
In this evidenced-based review, we examine the current available literature to help answer the question 'In neonates requiring long-term central access [patient], does removal of the umbilical venous catheter (UVC) on days 5-7 and replacement with a peripherally inserted central catheter line [intervention] compared with leaving the UVC in situ ...
Ireland Claire J CJ Department of Anaesthesia & Intensive Care, Dunedin Hospital, Great King Street, Dunedin, New - - 2014
Major abdominal surgery can be associated with a number of serious complications that may impair patient recovery. In particular, postoperative pulmonary complications (PPCs), including respiratory complications such as atelectasis and pneumonia, are a major contributor to postoperative morbidity and may even contribute to increased mortality. Continuous positive airway pressure (CPAP) ...
Starr Philip A PA Departments of Neurological - - 2014
Object The placement of deep brain stimulation (DBS) leads in adults is traditionally performed using physiological confirmation of lead location in the awake patient. Most children are unable to tolerate awake surgery, which poses a challenge for intraoperative confirmation of lead location. The authors have developed an interventional MRI (iMRI)-guided ...
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