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Dowman J K - - 2012
Early liver transplant (LT) has been advocated for patients with cystic fibrosis liver disease (CFLD) and evidence of deterioration in nutritional state and respiratory function to prevent further decline. However, the impact of single LT on long-term respiratory function and nutritional status has not been adequately addressed. We performed a ...
Zeng Dexin - - 2011
Recent studies have shown a positive correlation between the degree of severity of OA and the number of apoptotic chondrocytes. The purpose of our study was to determine the effect of therapeutic ultrasound on apoptosis in articular cartilage of rabbits with knee osteoarthritis (KOA). Thirty 3-month New Zealand White rabbits ...
Ghosh Partha S - - 2011
OBJECTIVE:: We studied neurological complications (NC) after liver transplantation (LT) in children. METHODS:: We performed an IRB-approved retrospective review of LT patients ≤ 21 years over a period of 30 years (1980-2010). NC were classified as early (within 3 months post-LT) and delayed (beyond 3 months post-LT). RESULTS:: Of 65 ...
Dimar John R JR - - 2011
A major sequelae of lumbar fusion is acceleration of adjacent-level degeneration due to decreased lumbar lordosis. We evaluated the effectiveness of 4 common fusion techniques in restoring lordosis: instrumented posterolateral fusion, translumbar interbody fusion, anteroposterior fusion with posterior instrumentation, and anterior interbody fusion with lordotic threaded (LT) cages (Medtronic Sofamor ...
O'Shaughnessy Brian A - - 2011
ABSTRACT: Study Design: Retrospective clinicoradiographic analysis.Objective: To compare the upper thoracic (UT) and lower thoracic (LT) spine as the upper-instrumented vertebra (UIV) in primary fusions to the sacrum for adult scoliosis.Summary of Background Data: The optimal level at which a fusion to the sacrum is terminated proximally for adult scoliosis ...
Brandman Danielle - - 2011
BACKGROUND: Hepatic encephalopathy (HE) does not enhance the prediction of model of end-stage liver disease (MELD) wait-list mortality, but its influence on post-liver transplantation (LT) morbidity and mortality is largely unknown. AIMS: To examine the association between severe pre-LT HE and peri-LT serum sodium levels as well as post-LT length ...
Xia Lu - - 2011
The aim of this study is to observe the effect of different treatment time of millimeter wave (MMW) on chondrocyte apoptosis, caspase-3, caspase-8, and matrix metalloproteinase-13 (MMP-13) in rabbit knee osteoarthritis induced by anterior cruciate ligament transection (ACLT). Thirty-two New Zealand White rabbits were randomly assigned into 4 groups: millimeter ...
Gahan Kelly - - 2011
Objective: The objective of this study was to compare the frequency of first attempt success between basic life support (BLS) first responder initiated King LT-D placement and paramedic initiated endotracheal intubation (ETI) among patients experiencing out-of-hospital cardiac arrest (OOHCA). Methods: In 2009 a large, urban EMS agency modified their out-of-hospital, ...
Botser Itamar B - - 2011
The ligamentum teres (LT) anatomy has been known for many years. While its functionality remains debatable, it is well recognized that the LT can be a source of pain in the hip joint. In 1997, a landmark publication by Gray and Villar established a classification for LT tears and increased ...
Li Qi-Yong - - 2011
Background/Aims: Differentiating surgical jaundice from non-surgical jaundice is of vital importance after liver transplantation (LT) and endoscopic retrograde cholangiopancreatography (ERCP) is not effective for all anastomotic stricture (AS) cases. In the present study, we aim to determine the optimal indication of ERCP treatment for AS after LT. Methodology: Twenty-eight jaundice ...
Ardiles Victoria - - 2011
Bile duct injury (BDI) is a severe complication that may arise during the surgical treatment of benign disease and a few patients will develop end-stage liver disease (ESLD) requiring a liver transplant (LT). Objective: Analyse the experience using LT as a definitive treatment of BDI in Argentina. A national survey ...
Alli Oluseun - - 2011
The benefits of dual antiplatelet therapy are counterbalanced by the increased incidence of gastrointestinal (GI) complications. The aim of this study was to determine the frequency of GI bleeding, identify the predictors associated with the increased bleeding, and determine the short-term and long-term outcomes. This was an observational, case-control cohort ...
Lin Chun-Ju - - 2011
Reactive macular edema can occur following photodynamic therapy (PDT) in patients who have undergone fluorescein angiography (FA) on the same day. It might be better not to perform PDT on the same day of FA to avoid side effects. The safety interval between FA and PDT should be at least ...
Zundel Sabine - - 2011
OBJECTIVE: To demonstrate a rare case of urological pathology, we report a combination of a single kidney and ureteral atresia. The treatment concept and outcome are outlined. PATIENT AND METHOD: Antenatal ultrasound had revealed urinary ascites which lead to caesarean section in the 34th gestational week. Persisting anuria was confirmed ...
Whitson Matthew J - - 2011
To assess prospectively the bleeding risk attributable to gastroduodenal biopsy in subjects taking antiplatelet medications. No prospective data exist regarding the bleeding risk attributable to endoscopic biopsy in patients taking antiplatelet agents. A majority of Western endoscopists withdraw antiplatelet agents before upper endoscopy, despite expert guidelines to the contrary. We ...
Zaina Fabio - - 2011
The SPoRT (acronym: Symmetrical, Patient-oriented, Rigid, Three-dimensional, active) concept of bracing is a new way to build braces based on our 20 years of experience and the biomechanical principles of scoliosis correction, inclusive of the Sibilla and Sforzesco braces. The concept always requires a custom brace, which is made according ...
Pigot F - - 2011
As little data is available about secondary bleeding after proctological surgery, we conducted a specific survey. Patients operated between November 2008 and April 2009 were prospectively included. Patients were followed until last visit (day 21-28). Severity of bleeding was low (at home stay), moderate (hospitalisation for observation), or severe (transfusion, ...
Berntorp E - - 2011
Summary.  Despite improvements in therapy that has greatly enhanced the treatment of patients with haemophilia with inhibitors, they are still at risk of poorer outcomes including haemophilic arthropathy and long-term disability. The objective of this review is to consider clinical data on the effect of rapid control of bleeding episodes ...
Nishida Osamu - - 2011
Sustained high-efficiency daily diafiltration using a mediator-adsorbing membrane (SHEDD-fA) is an effective, intensive modality for sepsis treatment. Here we describe the effectiveness of SHEDD-fA, which makes the best use of three principles: dialysis, filtration and adsorption, for mediator removal in the treatment of severe sepsis. SHEDD-fA was initiated after adequate ...
Jeong Woo-Jin - - 2011
Objective. Tissue eosinophilia is a hallmark of nasal polyposis. However, there is no universally accepted definition for eosinophilic nasal polyp. The aims of this study were to histologically analyze the inflammatory cell population in the nasal polyp and propose the concept of eosinophilic allergic polyp (EAP), a simple and objective ...
Chen Tsung-Hsing - - 2010
To evaluate the efficacy of endoscopic diagnosis and therapy for jejunal diverticular bleeding. From January 2004 to September 2009, 154 patients underwent double-balloon enteroscopy (DBE) for obscure gastrointestinal bleeding. Ten consecutive patients with jejunal diverticula (5 males and 5 females) at the age of 68.7 ± 2.1 years (range 19- ...
Muensterer O J - - 2011
Bleeding is a dreaded complication of extracorporeal membrane oxygenation (ECMO). At our institution, we use a bleeding protocol (BP) with or without ε-amino caproic acid (ACA) for certain prophylactic or therapeutic indications. Subjectively, we have felt that placing a child on bleeding protocol shortens the circuit life because of clot ...
Hu Ming-Luen - - 2010
To identify the predictors of rebleeding after initial hemostasis with epinephrine injection (EI) in patients with high-risk ulcers. Recent studies have revealed that endoscopic thermocoagulation, or clips alone or combined with EI are superior to EI alone to arrest ulcer bleeding. However, the reality is that EI monotherapy is still ...
Zanon Ezio - - 2011
Reports of intracerebral hemorrhage (ICH) in patients with hemophilia B are relatively rare. We describe the first clinical results of the use of a monoclonal antibody purified factor IX (FIX) concentrate (Mononine) after an ICH and the long-term outcome of prophylaxis with this product to prevent recurrences. A 44-year-old male ...
DE Podestá Haje D - - 2011
Summary.  There is a lack of publications concerning the use of primary prophylaxis in developing countries. The aim of this study was to evaluate the effectiveness of primary prophylaxis therapy in preventing the development of arthropathy in children with severe haemophilia A or B. From January 1999 to April 2009, ...
Millner Russell W J - - 2011
Objective: To explore the effectiveness of Omni-Stat(®) (Chitosan) in a model of major haemorrhage in the presence of clotting dysfunction. Method: A total of 12 major femoral artery bleeds in moderately heparinised swine treated with Omni-Stat(®) (Chitosan) were compared with five control bleeds. Results: Haemostasis was successfully achieved at first ...
Beyer R - - 2010
  Muscle haematomas (MH) represent 10-25% of all bleeds in patients with severe haemophilia. We performed a cross-sectional survey on current practice in the management of MH with participation from 22 consultants. The respondents reported 492 MH/year, corresponding an average of 25/centre, mostly associated with trauma. Iliopsoas (55%), calf (18%) ...
Oldenburg J - - 2010
  Postauthorization safety surveillance of factor VIII (FVIII) concentrates is essential for assessing rare adverse event incidence. We determined safety and efficacy of ADVATE [antihaemophilic factor (recombinant), plasma/albumin-free method, (rAHF-PFM)] during routine clinical practice. Subjects with differing haemophilia A severities and medical histories were monitored during 12 months of prophylactic ...
Spira J - - 2010
  Recombinant activated factor VIIa (FVIIa) is a bypassing agent used to treat bleeding episodes in haemophilia patients with inhibitors to factor VIII (FVIII) and factor IX. The pharmacological effect of FVIIa is short-lived and therefore with the recommended dose of 90 μg kg(-1), a bleeding episode is treated with ...
Ferri Emanuele - - 2011
Argon plasma coagulation (APC) is a new surgical procedure based on a conductive plasma of ionized argon between an activating electrode and a tissue surface. It is a good alternative for tonsillectomy because of its effective hemostasis and limited penetration depth of the coagulation beam. The aim of this prospective, ...
Katsinelos Panagiotis - - 2010
To prospectively compare partially covered vs uncovered sphincterotome use on post-endoscopic biliary sphincterotomy (ES) hemorrhage and other complications. All patients referred for therapeutic endoscopic retrograde cholangiopancreatography (ERCP) were randomly assigned to undergo ES either with a partially covered or an uncovered sphincterotome. Both patient and technical risk factors contributing to ...
Monte Andrew A - - 2010
To describe 3 episodes of low-molecular-weight heparin (LMWH) overdose in 2 patients and discuss the clinical presentations, outcomes, and therapeutic options. The first patient, a 35-year-old female, presented after an intentional overdose of 72,000 units of dalteparin. The peak measured anti-Xa activity was 6.2 U/mL at 7.5 hours postinjection. No ...
Ahmed T M - - 2010
Therapeutic angiography with embolization is fast becoming the preferred treatment modality for major bleeding in the lower gastrointestinal (LGI) tract. The aim of this study was to determine the long term outcome and complications of percutaneous coil embolization (PCE) and its efficacy as definitive therapy in patients with major LGI ...
Albu Silviu - - 2010
OBJECTIVE: To find out whether the constant preoperative use of a topical corticoid (mometasone furoate [MF]) could really improve the operative field quality and decrease bleeding during endoscopic sinus surgery (ESS). STUDY DESIGN: Double-blind, randomized controlled trial. SETTING: Tertiary referral center. SUBJECTS AND METHODS: Seventy patients with chronic rhinosinusitis (CRS) ...
Heiser Clemens - - 2010
OBJECTIVES/HYPOTHESIS: Persistent taste disturbance is a rare complication after tonsillectomy and mainly documented by case reports or a few retrospective and prospective trials with a limited number of patients. None could clarify frequency, time course, or prognosis of long-lasting dysgeusia after tonsillectomy. The aim of the study was to provide ...
Bowyer A - - 2011
Introduction:  An isolated prolongation to the activated partial thromboplastin time (APTT) can be caused by the presence of the lupus anticoagulant or an intrinsic or contact factor deficiency, of which only deficiencies of factors VIII, IX or XI are associated with bleeding. Our local protocol states that further investigation of ...
Fan Hongguang - - 2010
Upper gastrointestinal (GI) hemorrhage is a serious complication of coronary artery bypass grafting (CABG). The aim of this study was to retrospectively investigate the risk factors and prevention of upper GI bleeding after CABG. This study followed 6316 coronary patients who underwent CABG from 1998 to 2005. The perioperative parameters ...
Scaglione Giuseppe - - 2011
The influence of aging on video capsule endoscopy (VCE) in obscure gastrointestinal bleeding (OGIB) has never been prospectively assessed. To demonstrate if age is a risk factor for incomplete VCE examination in a setting of ongoing hospitalization for OGIB and if it affects the yield of VCE. Forty-eight consecutive patients ...
Kim Sung Hyun - - 2010
OBJECTIVE: To present bismuth subgallate as a simplified and efficient method for promoting hemostasis at palatal donor sites, as evaluated by measuring hemostasis time and delayed bleeding. METHOD AND MATERIALS: Ten patients received the bismuth subgallate paste as a topical hemostatic agent, while another 10 patients received moistened gauze pressure. ...
Hayes Helen M - - 2010
Gastrointestinal (GI) bleeding in ventricular assist devices (VADs) has been reported with rotary devices. The pathophysiological mechanisms and treatments are in evolution. We performed a retrospective review of GI bleeding episodes for all VADs implanted at our institution. Five male patients experienced GI bleeding-age 63.6 ± 3.64 years. VAD type ...
Elbarouni Basem - - 2010
BACKGROUND: Although randomized controlled trials support the use of intensive medical and invasive therapies for non-ST segment elevation acute coronary syndromes (NSTE-ACS), major bleeding is a serious treatment complication. We sought to determine the temporal trend of in-hospital major bleeding among patients with NSTE-ACS, in relation to the evolving management ...
Greenspoon Joshua - - 2010
Recommendations in managing patients with nonvariceal upper gastrointestinal bleeding were recently updated, addressing resuscitation, risk assessment and pre-endoscopic care, endoscopy, pharmacotherapy, and secondary prophylaxis. Initial adequate resuscitation and risk stratification using validated scales remain critical. Intravenous erythromycin improves visualization when likely to find blood in the stomach. Pre-endoscopic proton pump ...
Chiu Philip W Y - - 2010
To review recent literature (2009-2010) on acute nonvariceal upper gastrointestinal hemorrhage. There is a decreasing trend in the incidence and hospitalization for acute nonvariceal upper gastrointestinal hemorrhage worldwide, with significant improvement in rebleeding and mortality. One study showed that Glasgow-Blatchford score was superior to Rockall score in predicting the need ...
Berntorp Erik - - 2010
The nonactivated prothrombin complex concentrate (PCC) Octaplex (Octapharma PPGmbH, Vienna, Austria) has been used successfully for the treatment of congenital and acquired coagulation factor deficiencies and associated bleeding. The aims of this study were to assess retrospectively whether Octaplex is an effective treatment option for haemophilia A patients with high-titre ...
Dahl O E - - 2010
Anticoagulants are effective for the prevention of venous thromboembolism (VTE) but cause bleeding. Interpretation of the risks and benefits of new anticoagulant regimens for VTE prevention is complicated by a lack of standardized definitions and reporting of bleeding. We reviewed the reporting of bleeding in randomized controlled trials of new ...
Politi Luigi - - 2011
Background: Despite the increasing use of transradial techniques for cardiac percutaneous procedures, none of the strategies commonly utilized for hemostasis has been able to reduce the occurrence of radial artery occlusion (RAO). The aim of this study was to evaluate the occurrence of 24-hour RAO and the rate of bleeding ...
Liou W-S - - 2011
Summary.  This study compared secondary prophylaxis treatment with on-demand treatment for severe haemophilia A in Taiwan. Fifty patients from one medical centre were evaluated over a 5-year period. Differences in annual bleed rates and factor VIII (FVIII) utilization were assessed between patients receiving secondary prophylaxis and patients receiving FVIII concentrates ...
Tang Yu - - 2010
Active hemorrhage arising from hepatic injury can be life-threatening and require immediate attention. At present, nonoperative management of abdominal solid organ injuries has become the usual method of care. The purpose of this study was to determine whether hemocoagulase injection alone guided by contrast-enhanced ultrasonography (CEUS) could control active bleeding ...
Malik Rena - - 2010
To evaluate the efficacy of local compression and topical epinephrine in controlling perioperative bleeding during open radical retropubic prostatectomy (ORRP) and its impact on the degree of urinary extravasation on initial postoperative cystogram. Between September 2005 to March 2009, 476 men underwent ORRP performed by a single surgeon. Group 1 ...
Brown Colin - - 2010
Vascular malformation of the gastrointestinal tract is an uncommon cause for gastrointestinal bleeding. Traditionally, gastroenterologists prefer to use endoscopic modalities like argon plasma coagulation and electrocoagulation to treat accessible lesions. The role of somatostatin analogues (octreotide) in preventing recurrent bleeding in these patients is unclear. The use of pharmacological treatments ...
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