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Paldor Iddo I Department of Neurosurgery, Hadassah-Hebrew University Medical Center, POB 12000, Jerusalem 91120, - - 2014
Randomized controlled trials have demonstrated the efficacy of decompressive craniectomy in substantially decreasing mortality and improving functional outcome in middle cerebral artery infarction. The role of intracranial pressure (ICP) monitoring following decompressive craniectomy for stroke has not been well studied. We present a retrospective review of our experience with postoperative ...
Mandavia R R Academic Section of Vascular Surgery, Imperial College London, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, UK. Electronic address: - - 2014
Thrombolysis is effective in improving clinical outcome in the treatment of acute ischaemic stroke. However, thrombolysis results in low recanalisation rates, particularly in the event of carotid occlusion. Carotid intervention is indicated in stroke resulting from significant carotid atherosclerosis, but intervention soon after thrombolysis may be associated with increased risks. ...
Moosavian Hamid Reza HR Department of Clinical Science, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran, - - 2014
We sought to determine the effect of ischemic preconditioning (IPC) and hirudotherapy (leech therapy) on cutaneous pedicle flaps after they underwent prolonged ischemia (global ischemia) in a mouse model. Twenty cutaneous pedicle flaps were elevated in 20 mice, and the animals were randomized into four groups: sham, control, IPC and ...
Schmitz Marie Louise ML From the Department of Neurology, Aarhus University Hospital, Aarhus C, Denmark (M.L.S., C.Z.S., G.A.); Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus N, Denmark (H.H., S.P.J.); Department of Neurology, Bispebjerg Hospital, Copenhagen, Denmark (H.C.); Department of Neurology, Roskilde Hospital, Roskilde, Denmark (K.E.); Department of Neurology, Holstebro Hospital, Holstebro, Denmark (K.G.); Department of Neurology, Glostrup Hospital, Glostrup, Denmark (H.I.); Department of Neurology, Odense University Hospital, Odense C, Denmark (C.M.); Department of Neurology, Esbjerg Hospital, Esbjerg, Denmark (M.-J.R.); and Department of Neurology, Aalborg University Hospital, Aalborg, Denmark (K.V.). - - 2014
Data on long-term outcome after intravenous tissue-type plasminogen activator (tPA) in ischemic stroke are limited. We examined the risk of long-term mortality, recurrent ischemic stroke, and major bleeding, including intracranial and gastrointestinal bleeding, in intravenous tPA-treated patients when compared with intravenous tPA eligible but nontreated patients with ischemic stroke. We ...
Campos-Pires Rita R 1Anaesthetics, Pain Medicine and Intensive Care Section, Department of Surgery and Cancer, Imperial College London, London, United Kingdom. 2Department of Anaesthesiology, Medical Center of Johannes Gutenberg University, Mainz, Germany. 3Department of Anaesthesiology, Klinikum Hanau, Hanau, Germany. 4Mouse Behavioral Outcome Unit, Focus Program Translational Neurosciences, Johannes Gutenberg University, Mainz, Germany. 5Department of Life Sciences, Imperial College London, London, United - - 2014
To determine the neuroprotective efficacy of the inert gas xenon following traumatic brain injury and to determine whether application of xenon has a clinically relevant therapeutic time window. Controlled animal study. University research laboratory. Male C57BL/6N mice (n = 196). Seventy-five percent xenon, 50% xenon, or 30% xenon, with 25% ...
Pan Yuesong Y Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases (NCRC-ND), Beijing, - - 2014
Stroke Prognostication using Age and NIH (National Institutes of Health) Stroke Scale (SPAN)-100 is a simple and easy-to-use tool for assessing the outcomes of ischemic stroke after thrombolysis. To explore its application, we evaluated SPAN-100's prognostic value in predicting 3- and 12-month outcomes in general ischemic stroke patients. We applied ...
Cho Won-Sang WS From the Departments of Neurosurgery (W.-S.C., J.E.K., C.H.K., S.P.B., H.-S.K., Y.J.S., J.S.B., C.W.O.), Radiology (C.-H.S.), and Nuclear Medicine (J.C.P.), Seoul National University College of Medicine, Seoul, - - 2014
The surgical outcomes of adult moyamoya disease are rarely reported. We aimed to evaluate the long-term outcomes of combined revascularization surgery in patients with adult moyamoya disease. Combined revascularization surgery consisting of superficial temporal artery-middle cerebral artery anastomosis with encephalodurogaleosynangiosis was performed on 77 hemispheres in 60 patients. Clinical, angiographic, ...
Gomes Helbert Minuncio Pereira HM University Nove de Julho, São Paulo, SP, - - 2014
The negative result of a research does not always indicate failure, and when the data do not permit a proper conclusion, or are contrary to the initial project, should not simply be discarded and archived. To report failure after performing experimental model of liver ischemia and reperfusion normothermic, continuous or ...
Arias Eric J EJ Department of Neurological - - 2014
Object Most patients with asymptomatic intracranial aneurysms treated with endovascular methods are closely observed overnight in an intensive care unit setting for complications, including ischemic and hemorrhagic stroke, cardiac dysfunction, and groin access complications. The purpose of this study was to analyze the timing, nature, and rate of in-house postoperative ...
Ares Oscar O Orthopedic Department, Hospital Clinic Barcelona, University of Barcelona, Barcelona, - - 2014
Drainages in primary knee arthroplasty remain unclear. Our aim is to analyze variables that may affect bleeding in knee arthroplasty (age, drained volume, and ischemia time). We included 188 knee arthroplasties, divided into three groups: conventional approach for total knee arthroplasty (TKA), minimally invasive total knee arthroplasty (MIS), and unicompartmental ...
Douvali Maria M 2nd Department of Ophthalmology, Attikon Hospital, Athens, - - 2014
Purpose: To evaluate the impact of macular ischemia on the functional and anatomical outcome after intravitreal injections of ranibizumab for the treatment of diabetic macular edema (DME). Procedures: Participants were 49 patients with diabetes mellitus, divided into two groups based on the presence of ischemia on fluorescein angiography: (i) nonischemic ...
McAlpine Heidi H Melbourne Brain Centre, Royal Melbourne Hospital, Melbourne, - - 2014
Early neurological recovery after intravenous thrombolysis (IVT) is associated with favorable outcome after acute ischemic stroke. Leukoaraiosis, a marker of chronic ischemia, is a possible negative predictive factor of early recovery. However, its negative attenuating effects remain inadequately studied, leading to uncertainty in the prediction of outcomes after IVT. We ...
Hu Sheng-Li SL Department of Neurosurgery, Southwest Hospital, Third Military Medical University, Gaotanyan 29, Shapingba District, Chong-Qing, 400038, People's Republic of - - 2014
Neurosurgical operations may result in surgical injury which would lead to postoperative neurological deficits. Hyperbaric oxygen preconditioning (HBO-PC) may be beneficial for such people. However, the exact mechanism underlying HBO-PC is not well known yet. The aim of this study is to explore the role of osteopontin (OPN) in HBO-PC-induced ...
Asaithambi Ganesh G Department of Neurology, University of Florida College of Medicine, Gainesville, Florida. Electronic address: - - 2014
The American Heart Association/American Stroke Association (AHA/ASA) recommended an expansion of the time window for acute ischemic stroke (AIS) reperfusion with intravenous (IV) recombinant tissue plasminogen activator (rt-PA) from 3 to 4.5 hours after symptom onset. We examine rates of IV and intra-arterial (IA) reperfusion before and after the recommendations to ...
Jones Helen H Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK - - 2014
Ischaemic preconditioning has well-established cardiac and vascular protective effects. Short interventions (one week) of daily ischaemic preconditioning episodes improve conduit and microcirculatory function. This study examined whether a longer (eight weeks) and less frequent (three per week) protocol of repeated ischaemic preconditioning improves vascular function. Eighteen males were randomly allocated ...
Triebel Kristen L KL Department of Neurology, Division of Neuropsychology, University of Alabama at Birmingham (UAB), Birmingham, - - 2014
To investigate recovery of medical decision-making capacity (MDC) over six-months in persons with traumatic brain injury (TBI) stratified by injury severity. Longitudinal study comparing controls and TBI patients one month after injury (T1) and six-months after injury (T2). Inpatient TBI rehabilitation unit and outpatient neurology department. 60 controls and 91 ...
Ahmad Ansari Muhammad Zubair AM Department of Cardiac Surgery, Ch. Pervaiz Elahi Institute of Cardiology, Multan, - - 2014
To evaluate the impact of remote ischemic preconditioning (RIPC) on clinical outcome, biological markers of myocardial injury, and its safety in patients undergoing on-pump coronary artery bypass grafting (CABG). This study was conducted at Ch. Pervaiz Elahi Institute of Cardiology (CPEIC) in Multan. The study took place from March 2012 ...
Girardi Leonard N LN Department of Cardiothoracic Surgery, Weill Cornell Medical College, New York, NY. Electronic address: - - 2014
The best adjunct for cerebral protection during aortic arch reconstruction remains controversial. Retrograde cerebral perfusion (RCP) as an adjunct to profound hypothermic circulatory arrest (PHCA) extends the tolerable period of brain ischemia by flushing emboli and air from the cerebral circulation while maintaining hypothermia. We examined our experience with RCP ...
Khatchadourian Karine - - 2013
To describe patient characteristics at presentation, treatment, and response to treatment in youth with gender dysphoria. A retrospective chart review of 84 youth with a diagnosis of gender dysphoria seen at BC Children's Hospital from 1998-2011. Of the 84 patients, 45 (54%) identified as female-to-male (FtM), 37 (44%) as male-to-female ...
Bernardini Francesco P - - 2013
The forehead/brow complex, the temporal region, the upper eyelid, the zygomatic area, the lower eyelid, and the cheek comprise the periocular esthetic unit. The combination of variable degrees of tissue descent and fat deflation of the component parts of the unit determine its appearance with age. The authors report the ...
Koul Roshan - - 2012
Myasthenia gravis is an autoimmune neuromuscular disorder caused by circulating antibodies that block acetylcholine receptors at the postsynaptic neuromuscular junction. A wide range of symptomatic therapy with acetylcholinesterase inhibitors and immunotherapy such as corticosteroids, azathioprine, cyclosporine, mycophenolate mofetil, plasmapheresis, and intravenous immunoglobulin has been used in the treatment of myasthenia gravis, ...
Cramer Gregory D - - 2012
The purpose of this study was to use previously validated methods to quantify and relate 2 phenomena associated with chiropractic spinal manipulative therapy (SMT): (1) cavitation and (2) the simultaneous gapping (separation) of the lumbar zygapophyseal (Z) joint spaces. This was a randomized, controlled, mechanistic clinical trial with blinding. Forty ...
Gill I P S - - 2012
We present a series of 35 patients (19 men and 16 women) with a mean age of 64 years (36.7 to 75.9), who underwent total hip replacement using the ESKA dual-modular short stem with metal on-polyethylene bearing surfaces. This implant has a modular neck section in addition to the modular ...
Nakasone Satoshi - - 2012
The purpose of this study was to retrospectively investigate the incidence of initial polar gaps and their effect on clinical results in Birmingham Hip Resurfacing cups. A total of 151 hips in 134 patients who underwent hip resurfacing at a mean age of 50 years were examined. The mean follow-up ...
García-Aparicio L - - 2012
PURPOSE: We describe the efficacy of dilation of the ureterovesical junction to treat primary obstructive megaureter. MATERIALS AND METHODS: A total of 13 patients with primary obstructive megaureter were treated from May 2008 to December 2010. Of these patients 8 were diagnosed prenatally and the others were diagnosed after a ...
Femenía Francisco - - 2012
A 34-week premature neonate presented with drug-refractory permanent junctional incessant tachycardia and haemodynamic compromise. The patient underwent successful radiofrequency catheter ablation using a single-catheter approach. The child remains in sinus rhythm, without pharmacological treatment, 2 years after the procedure.
Szakál Orsolya - - 2012
Abstract Objective: Gastric-arterial partial CO(2) pressure gap (P(g-a)CO(2) gap) measured by gastric tonometry may detect the disturbance of splanchnic perfusion. Since in the neonatal age it is very difficult to follow up the circulatory condition with frequent acid-base examinations, we wanted to compare the P(g-a)CO(2) gap with an alternative gap ...
Al-Ali Firas - - 2012
BackgroundDespite increased recanalization rates in the treatment of acute ischemic stroke, the percentage of patients with a good clinical outcome of all those treated has not risen above 50%. This 50% barrier may be broken by improving the criteria for treatment selection. This study investigated the addition of the capillary ...
Strandberg Erika - - 2012
BACKGROUND: The interplay between mechanical dilatation, resorption, and arterial response following implantation of bioresorbable scaffolds is still poorly understood. METHODS AND RESULTS: Long-term geometric changes in porcine coronary arteries in relation to gradual degradation of bioresorbable scaffolds were assessed in comparison with bare metal stents (BMS). Intravascular ultrasound (IVUS)-derived lumen, ...
Choi Jae Duck - - 2012
PURPOSE: We determined the effects of warm ischemia time on the recovery of renal function after partial nephrectomy under pneumoperitoneum. MATERIALS AND METHODS: In this prospective study 37 consecutive patients who underwent laparoscopic partial nephrectomy or robot-assisted partial nephrectomy between June 2008 and May 2009 to remove a single cT1 ...
Graversen Joseph A - - 2012
OBJECTIVE: To evaluate the effect that a safety wire (SW) had on insertion force and direct ureteral trauma using ureteral access sheaths (UAS) in an ex vivo porcine model. MATERIAL AND METHODS: UASs were advance into 20 fresh ex vivo porcine kidney-ureters, either with or without SWs. The average and ...
Hocini Mélèze M Hôpital Cardiologique du Haut Lévêque Université Victor Segalen Bordeaux II, Bordeaux, Pessac, France. - - 2012
To evaluate the safety and outcomes of mitral isthmus (MI) linear ablation with temporary spot occlusion of the coronary sinus (CS). CS blood flow cools local tissue precluding transmurality and bidirectional block across MI lesion. In a randomized, controlled trial (CS-occlusion = 20, Control = 22), MI ablation was performed ...
Cocchiarella Antonio - - 2012
Extensive research in the past decade has confirmed that the adult brain maintains some plasticity, including neural cell birth, migration and integration. Pre-clinical data strongly suggest that phosphodiesterase type 5 (PDE5) inhibitors promote cerebral neovascularization and neurogenesis. Animal studies of cerebral stroke suggest potential regenerative benefits following treatment with sildenafil ...
Verma Rajesh - - 2012
A teenage girl presented with progressively worsening neck and occipital pain since 8 months ago that was associated with restriction of neck movements, low to moderate grade fever, anorexia and weight loss followed by gradually progressive quadriparesis since 3 months ago. Neurological examination revealed spastic quadriparesis without cranial nerve palsy. MRI of ...
Vajda Zsolt - - 2012
Balloon dilatation and deployment of a self-expanding stent is a safe treatment for intracranial atherosclerotic stenoses. The significant recurrence rate might be related to the high radial force of the Wingspan stent. To evaluate the procedural safety and stenosis recurrence rate by the use of a stent with reduced radial ...
Pearson Scott - - 2011
To the Editor: The investigators in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation study (ROCKET AF; ClinicalTrials.gov number, NCT00403767) (Sept. 8 issue)(1) reported that rivaroxaban was noninferior to warfarin in preventing stroke or ...
- - 2011
To the Editor: The investigators in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation study (ROCKET AF; ClinicalTrials.gov number, NCT00403767) (Sept. 8 issue)(1) reported that rivaroxaban was noninferior to warfarin in preventing stroke or ...
Rosenstein Robert - - 2011
To the Editor: The investigators in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation study (ROCKET AF; ClinicalTrials.gov number, NCT00403767) (Sept. 8 issue)(1) reported that rivaroxaban was noninferior to warfarin in preventing stroke or ...
Rose Adam - - 2011
To the Editor: The investigators in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation study (ROCKET AF; ClinicalTrials.gov number, NCT00403767) (Sept. 8 issue)(1) reported that rivaroxaban was noninferior to warfarin in preventing stroke or ...
Sakai T - - 2011
BACKGROUND: /st>Intraoperative pulmonary thromboembolism (PTE) is an often overlooked cause of mortality during adult liver transplantation (LT) with diagnostic challenge. The goals of this study were to investigate the incidence, clinical presentation, and outcome of PTE and to identify risk factors or diagnostic predictors for PTE. METHODS: /st>Four hundred and ...
Niessner Alexander - - 2011
To the Editor: The investigators in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation study (ROCKET AF; ClinicalTrials.gov number, NCT00403767) (Sept. 8 issue)(1) reported that rivaroxaban was noninferior to warfarin in preventing stroke or ...
Bagul Atul - - 2011
OBJECTIVE: To analyze the effects of a right-sided-complex laparoscopic live donor nephrectomy, defined as bifurcation of the right renal artery behind the inferior vena cava. Right-sided laparoscopic live donor nephrectomy is now a widely accepted procedure when complex anatomy is encountered on the left. TECHNICAL CONSIDERATIONS: The present retrospective case ...
Fernández-Ortega Juan Francisco - - 2011
A proportion of patients surviving severe Traumatic Brain Injury (TBI) present symptoms suggestive of excessive sympathetic discharge, here termed Paroxysmal Sympathetic Hyperactivity (PSH). Aims: 1) To describe the clinical associations and radiological findings of PSH, its incidence and features in subjects with severe TBI in the Intensive Care Unit (ICU). ...
Szendro G - - 2011
Femoro above knee popliteal bypass using synthetic graft is a well recognized revascularization procedure in patients with severe lower limb ischemia with either critical limb ischemia (CLI), limiting claudication (IC) or with acute limb ischemia (ALI).Occasionally the patient's general condition would mandate a short and minimally invasive procedure. When endovascular ...
Moretti Claudio - - 2011
Aims: This new generation of DES has attempted to improve clinical safety by avoiding the presence of polymers. The present preclinical in vivo study was designed to investigate the safety profile of Cre8™ stent. This is a new coronary stent based on Amphilimus™, a sirolimus formulated with a polymer-free amphiphilic ...
Tenser Matthew S - - 2011
Intracranial large-vessel ischemia is associated with poor clinical outcome and increased mortality. Early reperfusion of ischemic tissue remains the goal of treatment of stroke. Intravenous tissue plasminogen activator (IV tPA) has been shown to improve clinical outcomes for patients who experience ischemic stroke, but it has been shown to be ...
Christoforidis Gregorgy - - 2011
Background and PurposeSignificant 24 h improvement is the strongest indicator of functional recovery following thrombolytic treatment for acute ischemic stroke. This study sought to analyze factors contributing to rapid neurological improvement (RNI) following intra-arterial thrombolytic treatment (IATT).MethodsAngiograms and clinical information derived from consecutive patients receiving treatment initiated within 6 h ...
Chen Ying-Hsien - - 2011
OBJECTIVES: Asymptomatic critical internal carotid artery (ICA) stenosis may lead to cognitive impairment. Carotid stenting (CS) may improve cerebral perfusion, but its impact on neuro-cognitive function has been controversial. METHODS: We prospectively enrolled 34 asymptomatic patients with unilateral ICA stenosis or occlusion, in whom CS was attempted. Computed tomography cerebral ...
Pedrini Luciano - - 2012
Guidelines do not include cerebral oximetry among monitoring for carotid endarterectomy (CEA). The purpose of this study was to evaluate the reliability of near-infrared spectroscopy (NIRS) in the detection of clamping ischemia and in the prevention of clamping-related neurologic deficits using, as a cutoff for shunting, a 20% regional cerebral ...
Powers William J - - 2011
Patients with symptomatic atherosclerotic internal carotid artery occlusion (AICAO) and hemodynamic cerebral ischemia are at high risk for subsequent stroke when treated medically. To test the hypothesis that extracranial-intracranial (EC-IC) bypass surgery, added to best medical therapy, reduces subsequent ipsilateral ischemic stroke in patients with recently symptomatic AICAO and hemodynamic ...
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