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Khatchadourian Karine - - 2013
To describe patient characteristics at presentation, treatment, and response to treatment in youth with gender dysphoria. A retrospective chart review of 84 youth with a diagnosis of gender dysphoria seen at BC Children's Hospital from 1998-2011. Of the 84 patients, 45 (54%) identified as female-to-male (FtM), 37 (44%) as male-to-female ...
Bernardini Francesco P - - 2013
The forehead/brow complex, the temporal region, the upper eyelid, the zygomatic area, the lower eyelid, and the cheek comprise the periocular esthetic unit. The combination of variable degrees of tissue descent and fat deflation of the component parts of the unit determine its appearance with age. The authors report the ...
Koul Roshan - - 2012
Myasthenia gravis is an autoimmune neuromuscular disorder caused by circulating antibodies that block acetylcholine receptors at the postsynaptic neuromuscular junction. A wide range of symptomatic therapy with acetylcholinesterase inhibitors and immunotherapy such as corticosteroids, azathioprine, cyclosporine, mycophenolate mofetil, plasmapheresis, and intravenous immunoglobulin has been used in the treatment of myasthenia gravis, ...
Cramer Gregory D - - 2012
The purpose of this study was to use previously validated methods to quantify and relate 2 phenomena associated with chiropractic spinal manipulative therapy (SMT): (1) cavitation and (2) the simultaneous gapping (separation) of the lumbar zygapophyseal (Z) joint spaces. This was a randomized, controlled, mechanistic clinical trial with blinding. Forty ...
Gill I P S - - 2012
We present a series of 35 patients (19 men and 16 women) with a mean age of 64 years (36.7 to 75.9), who underwent total hip replacement using the ESKA dual-modular short stem with metal on-polyethylene bearing surfaces. This implant has a modular neck section in addition to the modular ...
Nakasone Satoshi - - 2012
The purpose of this study was to retrospectively investigate the incidence of initial polar gaps and their effect on clinical results in Birmingham Hip Resurfacing cups. A total of 151 hips in 134 patients who underwent hip resurfacing at a mean age of 50 years were examined. The mean follow-up ...
García-Aparicio L - - 2012
PURPOSE: We describe the efficacy of dilation of the ureterovesical junction to treat primary obstructive megaureter. MATERIALS AND METHODS: A total of 13 patients with primary obstructive megaureter were treated from May 2008 to December 2010. Of these patients 8 were diagnosed prenatally and the others were diagnosed after a ...
Femenía Francisco - - 2012
A 34-week premature neonate presented with drug-refractory permanent junctional incessant tachycardia and haemodynamic compromise. The patient underwent successful radiofrequency catheter ablation using a single-catheter approach. The child remains in sinus rhythm, without pharmacological treatment, 2 years after the procedure.
Szakál Orsolya - - 2012
Abstract Objective: Gastric-arterial partial CO(2) pressure gap (P(g-a)CO(2) gap) measured by gastric tonometry may detect the disturbance of splanchnic perfusion. Since in the neonatal age it is very difficult to follow up the circulatory condition with frequent acid-base examinations, we wanted to compare the P(g-a)CO(2) gap with an alternative gap ...
Al-Ali Firas - - 2012
BackgroundDespite increased recanalization rates in the treatment of acute ischemic stroke, the percentage of patients with a good clinical outcome of all those treated has not risen above 50%. This 50% barrier may be broken by improving the criteria for treatment selection. This study investigated the addition of the capillary ...
Strandberg Erika - - 2012
BACKGROUND: The interplay between mechanical dilatation, resorption, and arterial response following implantation of bioresorbable scaffolds is still poorly understood. METHODS AND RESULTS: Long-term geometric changes in porcine coronary arteries in relation to gradual degradation of bioresorbable scaffolds were assessed in comparison with bare metal stents (BMS). Intravascular ultrasound (IVUS)-derived lumen, ...
Choi Jae Duck - - 2012
PURPOSE: We determined the effects of warm ischemia time on the recovery of renal function after partial nephrectomy under pneumoperitoneum. MATERIALS AND METHODS: In this prospective study 37 consecutive patients who underwent laparoscopic partial nephrectomy or robot-assisted partial nephrectomy between June 2008 and May 2009 to remove a single cT1 ...
Graversen Joseph A - - 2012
OBJECTIVE: To evaluate the effect that a safety wire (SW) had on insertion force and direct ureteral trauma using ureteral access sheaths (UAS) in an ex vivo porcine model. MATERIAL AND METHODS: UASs were advance into 20 fresh ex vivo porcine kidney-ureters, either with or without SWs. The average and ...
Hocini Mélèze M Hôpital Cardiologique du Haut Lévêque Université Victor Segalen Bordeaux II, Bordeaux, Pessac, France. - - 2012
To evaluate the safety and outcomes of mitral isthmus (MI) linear ablation with temporary spot occlusion of the coronary sinus (CS). CS blood flow cools local tissue precluding transmurality and bidirectional block across MI lesion. In a randomized, controlled trial (CS-occlusion = 20, Control = 22), MI ablation was performed ...
Cocchiarella Antonio - - 2012
Extensive research in the past decade has confirmed that the adult brain maintains some plasticity, including neural cell birth, migration and integration. Pre-clinical data strongly suggest that phosphodiesterase type 5 (PDE5) inhibitors promote cerebral neovascularization and neurogenesis. Animal studies of cerebral stroke suggest potential regenerative benefits following treatment with sildenafil ...
Verma Rajesh - - 2012
A teenage girl presented with progressively worsening neck and occipital pain since 8 months ago that was associated with restriction of neck movements, low to moderate grade fever, anorexia and weight loss followed by gradually progressive quadriparesis since 3 months ago. Neurological examination revealed spastic quadriparesis without cranial nerve palsy. MRI of ...
Vajda Zsolt - - 2012
Balloon dilatation and deployment of a self-expanding stent is a safe treatment for intracranial atherosclerotic stenoses. The significant recurrence rate might be related to the high radial force of the Wingspan stent. To evaluate the procedural safety and stenosis recurrence rate by the use of a stent with reduced radial ...
Pearson Scott - - 2011
To the Editor: The investigators in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation study (ROCKET AF; ClinicalTrials.gov number, NCT00403767) (Sept. 8 issue)(1) reported that rivaroxaban was noninferior to warfarin in preventing stroke or ...
- - 2011
To the Editor: The investigators in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation study (ROCKET AF; ClinicalTrials.gov number, NCT00403767) (Sept. 8 issue)(1) reported that rivaroxaban was noninferior to warfarin in preventing stroke or ...
Rosenstein Robert - - 2011
To the Editor: The investigators in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation study (ROCKET AF; ClinicalTrials.gov number, NCT00403767) (Sept. 8 issue)(1) reported that rivaroxaban was noninferior to warfarin in preventing stroke or ...
Rose Adam - - 2011
To the Editor: The investigators in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation study (ROCKET AF; ClinicalTrials.gov number, NCT00403767) (Sept. 8 issue)(1) reported that rivaroxaban was noninferior to warfarin in preventing stroke or ...
Sakai T - - 2011
BACKGROUND: /st>Intraoperative pulmonary thromboembolism (PTE) is an often overlooked cause of mortality during adult liver transplantation (LT) with diagnostic challenge. The goals of this study were to investigate the incidence, clinical presentation, and outcome of PTE and to identify risk factors or diagnostic predictors for PTE. METHODS: /st>Four hundred and ...
Niessner Alexander - - 2011
To the Editor: The investigators in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation study (ROCKET AF; ClinicalTrials.gov number, NCT00403767) (Sept. 8 issue)(1) reported that rivaroxaban was noninferior to warfarin in preventing stroke or ...
Bagul Atul - - 2011
OBJECTIVE: To analyze the effects of a right-sided-complex laparoscopic live donor nephrectomy, defined as bifurcation of the right renal artery behind the inferior vena cava. Right-sided laparoscopic live donor nephrectomy is now a widely accepted procedure when complex anatomy is encountered on the left. TECHNICAL CONSIDERATIONS: The present retrospective case ...
Fernández-Ortega Juan Francisco - - 2011
A proportion of patients surviving severe Traumatic Brain Injury (TBI) present symptoms suggestive of excessive sympathetic discharge, here termed Paroxysmal Sympathetic Hyperactivity (PSH). Aims: 1) To describe the clinical associations and radiological findings of PSH, its incidence and features in subjects with severe TBI in the Intensive Care Unit (ICU). ...
Szendro G - - 2011
Femoro above knee popliteal bypass using synthetic graft is a well recognized revascularization procedure in patients with severe lower limb ischemia with either critical limb ischemia (CLI), limiting claudication (IC) or with acute limb ischemia (ALI).Occasionally the patient's general condition would mandate a short and minimally invasive procedure. When endovascular ...
Moretti Claudio - - 2011
Aims: This new generation of DES has attempted to improve clinical safety by avoiding the presence of polymers. The present preclinical in vivo study was designed to investigate the safety profile of Cre8™ stent. This is a new coronary stent based on Amphilimus™, a sirolimus formulated with a polymer-free amphiphilic ...
Tenser Matthew S - - 2011
Intracranial large-vessel ischemia is associated with poor clinical outcome and increased mortality. Early reperfusion of ischemic tissue remains the goal of treatment of stroke. Intravenous tissue plasminogen activator (IV tPA) has been shown to improve clinical outcomes for patients who experience ischemic stroke, but it has been shown to be ...
Christoforidis Gregorgy - - 2011
Background and PurposeSignificant 24 h improvement is the strongest indicator of functional recovery following thrombolytic treatment for acute ischemic stroke. This study sought to analyze factors contributing to rapid neurological improvement (RNI) following intra-arterial thrombolytic treatment (IATT).MethodsAngiograms and clinical information derived from consecutive patients receiving treatment initiated within 6 h ...
Chen Ying-Hsien - - 2011
OBJECTIVES: Asymptomatic critical internal carotid artery (ICA) stenosis may lead to cognitive impairment. Carotid stenting (CS) may improve cerebral perfusion, but its impact on neuro-cognitive function has been controversial. METHODS: We prospectively enrolled 34 asymptomatic patients with unilateral ICA stenosis or occlusion, in whom CS was attempted. Computed tomography cerebral ...
Pedrini Luciano - - 2012
Guidelines do not include cerebral oximetry among monitoring for carotid endarterectomy (CEA). The purpose of this study was to evaluate the reliability of near-infrared spectroscopy (NIRS) in the detection of clamping ischemia and in the prevention of clamping-related neurologic deficits using, as a cutoff for shunting, a 20% regional cerebral ...
Powers William J - - 2011
Patients with symptomatic atherosclerotic internal carotid artery occlusion (AICAO) and hemodynamic cerebral ischemia are at high risk for subsequent stroke when treated medically. To test the hypothesis that extracranial-intracranial (EC-IC) bypass surgery, added to best medical therapy, reduces subsequent ipsilateral ischemic stroke in patients with recently symptomatic AICAO and hemodynamic ...
Alonso de Leciñana María M Stroke Unit, Department of Neurology, University Hospital Ramón y Cajal, IRYCIS, Universidad de Alcalá de Henares, Madrid, Spain. - - 2012
Safety and efficacy of intravenous thrombolysis in stroke patients with recent transient ischemic attack are hotly debated. Patients suffering transient ischemic attack may present with diffusion-weighted imaging lesions, and although normal computed tomography would not preclude thrombolysis, the concern is that they may be at higher risk for hemorrhage post-thrombolysis ...
Kleinman Jonathan T - - 2012
Previous studies of pediatric intracerebral hemorrhage have investigated isolated intraparenchymal hemorrhage. The authors investigated whether detailed assessment of intraventricular hemorrhage enhanced outcome prediction after intracerebral hemorrhage. They prospectively enrolled 46 children, full-term to 17 years, median age 2.7 years, with spontaneous intraparenchymal hemorrhage and/or intraventricular hemorrhage. Outcome was assessed with ...
Fukuoka Takuya - - 2011
Patent foramen ovale (PFO) is an important etiology of ischemic stroke in young adults. We investigated factors contributing to recurrent ischemic stroke in patients with PFO. Subjects comprised 47 patients (mean age, 56.8 ± 14.2 years; range 23-74 years) with ischemic stroke due to PFO who were admitted to our hospital between April 2007 ...
Lima Brian - - 2011
The use of selective cerebral perfusion with warmer temperatures during circulatory arrest has been increasingly used for arch replacement over concerns regarding the safety of deep hypothermic circulatory arrest (DHCA). However, little data actually exist on outcomes after arch replacement and DHCA. This study examines modern results with DHCA for ...
Kasahara Yukiko - - 2012
Prior use of antiplatelet agents improves stroke outcome in patients undergoing thrombolytic therapy as shown by reduced arterial reocclusion, although the risk of cerebral hemorrhage can be increased. The effect of cilostazol, an antiplatelet drug that improves endothelial function through upregulation of intracellular cAMP, on cerebral hemorrhage after thrombolytic therapy ...
Giampalma Emanuela - - 2011
In liver transplantation (LT), biliary strictures (BS) are one of the most common complications. The aim of this study was to evaluate the efficacy of percutaneous treatment in the management of post-LT BS. From 1999 to 2007, 48 patients underwent percutaneous treatment of post-transplant BS. We divided the population into ...
DeCroos Francis Char - - 2011
PURPOSE/AIMS: This study investigates the efficacy of intravitreal bevacizumab (IVB) for cystoid macular edema (CME) secondary to central retinal vein occlusion (CRVO). Subgroup analysis was performed comparing early (within 90 days of CRVO onset) and late treatment (after 90 days) as well as perfused and ischemic subgroups. Retrospective review of ...
Pennekamp Claire W A - - 2011
PURPOSE OF REVIEW: The benefit of carotid endarterectomy (CEA) in patients with symptomatic severe carotid stenosis is highly dependent on the perioperative stroke rate. Cerebral monitoring plays an important role in reducing the perioperative stroke rate as it allows detection of the main causes of perioperative stroke, being embolism, intraoperative ...
Lupinacci Renato Arioni - - 2011
PURPOSE: To study outcomes and functional results of a telescopic straight ileo-anal anastomosis. METHODS: Thirty-six mongrel dogs were submitted to total proctocolectomy and telescopic straight ileo-anal anastomosis (ileal mucosa-submucosa pulled-through the rectal cuff). They were divided in 3 groups, sacrificed after one, two or eight weeks after the initial procedure. ...
Tütün Ufuk - - 2011
Background: Postoperative pulmonary dysfunction following cardiopulmonary bypass (CPB) usually develops secondary to the inflammatory process with contact activation, hypothermia, operative trauma, general anesthesia, atelectasis, pain, and pulmonary ischemia/reperfusion due to crossclamping. The aim of the present study was to evaluate the effects of an on-pump, normothermic, and beating-heart technique and ...
Carlson Andrew P - - 2011
The Carotid Occlusion Surgery Study (COSS) was an improvement over the Extracranial-Intracranial Bypass Study, which did not utilize physiological selection. To assess possible reasons for early closure of the COSS trial, we reviewed COSS methods used to identify high-risk patients and compared results with separate quantitative data. Increased oxygen extraction ...
Whittaker Peter - - 2011
Contrast medium administration during imaging and therapeutic procedures can cause renal injury, partly due to ischemia. Therefore, we hypothesized that brief ischemia and reperfusion episodes applied at a distant site - multiple balloon inflations and deflations during angioplasty - may serve as a remote-conditioning (RC) stimulus and thereby protect against ...
Turk Aquilla - - 2011
BackgroundTraditional treatment in acute ischemic stroke is based on time criteria when administering intravenous and intra-arterial therapies. However, recent evidence suggests that image-based criteria may be useful for selecting patients for intra-arterial interventions. The use of CT perfusion (CTP)-based criteria, regardless of time from symptom onset, in patient selection for ...
Olweny Ephrem O - - 2011
PURPOSE: In pre-clinical studies, acute erythropoietin (EPO) administration has been shown to mitigate the deleterious effects of ischemia/reperfusion injury. We reviewed our clinical experience with intraoperative EPO administration as a potential renoprotective agent during laparoscopic partial nephrectomy (LPN). METHODS: Patients who underwent LPN at our institution between August 2008 and ...
Calleja Ana I - - 2011
Insulin resistance (IR) may not only increase stroke risk, but could also contribute to aggravate stroke prognosis. Mainly through a derangement in endogenous fibrinolysis, IR could affect the response to intravenous thrombolysis, currently the only therapy proved to be efficacious for acute ischemic stroke. We hypothesized that high IR is ...
Algra Selma O - - 2011
OBJECTIVE: Deep hypothermic circulatory arrest (DHCA) and antegrade cerebral perfusion (ACP) are 2 cardiopulmonary bypass techniques applied in aortic arch repair. In recent literature, cerebral effects of both techniques have received most attention, whereas the consequences for other organs have not been thoroughly investigated. Therefore, in this study, the impact ...
Abreu Leonardo de Albuquerque Dos Santos Lde - - 2011
Purpose: The aim of the study was to compare the effects of renal ice slush hypothermia and the use of trimetazidine in the protection against ischemia/reperfusion (I/R) injury. Materials and Methods: Fifteen farm pigs were submitted to left kidney ischemia and right nephrectomy during the same procedure. Animals were divided ...
Avaro Jean-Philippe - - 2011
BACKGROUND:: To evaluate the feasibility of aortic balloon catheter occlusion in intra-abdominal hemorrhage. METHODS:: Effects of transfemoral diaphragmatic aortic balloon occlusion (ABO) have been evaluated in 25 pigs. The animals were submitted to incontrollable hemorrhage by a splenic trauma. Group 1 (n = 9) received fluid resuscitation with normal saline ...
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