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Results 101 - 150 of 1630
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Olweny Ephrem O - - 2011
PURPOSE: In pre-clinical studies, acute erythropoietin (EPO) administration has been shown to mitigate the deleterious effects of ischemia/reperfusion injury. We reviewed our clinical experience with intraoperative EPO administration as a potential renoprotective agent during laparoscopic partial nephrectomy (LPN). METHODS: Patients who underwent LPN at our institution between August 2008 and ...
Calleja Ana I - - 2011
Insulin resistance (IR) may not only increase stroke risk, but could also contribute to aggravate stroke prognosis. Mainly through a derangement in endogenous fibrinolysis, IR could affect the response to intravenous thrombolysis, currently the only therapy proved to be efficacious for acute ischemic stroke. We hypothesized that high IR is ...
Algra Selma O - - 2011
OBJECTIVE: Deep hypothermic circulatory arrest (DHCA) and antegrade cerebral perfusion (ACP) are 2 cardiopulmonary bypass techniques applied in aortic arch repair. In recent literature, cerebral effects of both techniques have received most attention, whereas the consequences for other organs have not been thoroughly investigated. Therefore, in this study, the impact ...
Abreu Leonardo de Albuquerque Dos Santos Lde - - 2011
Purpose: The aim of the study was to compare the effects of renal ice slush hypothermia and the use of trimetazidine in the protection against ischemia/reperfusion (I/R) injury. Materials and Methods: Fifteen farm pigs were submitted to left kidney ischemia and right nephrectomy during the same procedure. Animals were divided ...
Avaro Jean-Philippe - - 2011
BACKGROUND:: To evaluate the feasibility of aortic balloon catheter occlusion in intra-abdominal hemorrhage. METHODS:: Effects of transfemoral diaphragmatic aortic balloon occlusion (ABO) have been evaluated in 25 pigs. The animals were submitted to incontrollable hemorrhage by a splenic trauma. Group 1 (n = 9) received fluid resuscitation with normal saline ...
Zenonos Georgios - - 2011
BACKGROUND:: Despite abundant published support of patch angioplasty during carotid endarterectomy(CEA), primary-closure is still widely used. The reasons underlying the persistence of primary closure are not quite evident in the literature. OBJECTIVE:: To present our experience with primary closure in CEA, and provide a rationale for its persistent wide use. ...
Corcos Leonardo - - 2011
BACKGROUND Endovenous laser ablation (EVLA) was performed in the treatment of great and small saphenous veins (GSVs, SSVs), perforating veins (PVs), and varicose collaterals (VCs). OBJECTIVE To verify the outcome in PVs and VCs. MATERIALS AND METHODS Four hundred eighty-two limbs of 306 patients were studied. EVLA was performed on ...
Misselt A J AJ Division of Vascular and Interventional Radiology, Mayo Clinic, Rochester, MN, - - 2012
We present the midterm clinical outcomes and predictors of balloon angioplasty and stent placement in atherosclerotic femoropopliteal (FP) arterial disease. Between January 2002 and August 2006, 155 patients (men = 56%; 71.4 ± 10.5 years) underwent 171 FP angioplasty or stent for claudication (n = 82, 54%) or critical limb ...
Ntaios G - - 2011
Background: We aimed to analyze the rate and time distribution of pre- and post-morbid cerebrovascular events in a single ischemic stroke population, and whether these depend on the etiology of the index stroke. Methods: In 2,203 consecutive patients admitted to a single stroke center registry (ASTRAL), the ischemic stroke that ...
Albers Gregory W - - 2011
The goal of the Stroke Treatment Academic Industry Roundtable (STAIR) meetings is to advance the development of acute and restorative stroke therapies. Summary of Review- At the STAIR VII recommendations for strategies to maximize the use of intravenous thrombolytics through targeting public education, and the refinement of current treatment exclusion ...
Akbal E - - 2011
Ankaferd Blood Stopper (ABS) is an herbal extract that enhances mucosal healing. The aim of this study was to investigate the efficacy of ABS on the healing of the esophagus and prevention of stricture development after esophageal caustic injuries in rats. The study included 50 rats. Rats were divided into ...
Wu Yi-Ming - - 2011
The objective of this study was to evaluate the incidence of symptomatic and clinically silent embolic following carotid angioplasty and stent placement (CAS) with and without the use of an embolic protection device (EPD). Between January 2006 and April 2009, 76 patients with carotid stenosis underwent 79 CAS procedures (three ...
Schrijver A - - 2011
This study evaluates the short-term outcome of ultrasound-accelerated thrombolysis in patients with lower extremity ischemia caused by thromboembolic occlusions. A retrospective cohort study was conducted from December 2008 to May 2011 of 57 patients (42 men; median age, 66±11 years) undergoing 62 episodes of ultrasound-accelerated thrombolysis for thromboembolic arterial occlusions ...
Tarlov Nicholas - - 2011
Background Stenting of symptomatic intracranial atherosclerosis remains under investigation, yet this option to potentially avert subsequent stroke has been offered at select centers under humanitarian device exemption and off-label use for several years. Methods Retrospective case series of consecutive patients undergoing stenting with Wingspan and balloon mounted coronary stents for ...
Andriessen Teuntje - - 2011
Changes in the demographics, approach and treatment of Traumatic Brain Injury (TBI) patients require regular evaluation of epidemiologic profiles, injury severity classification and outcomes. This prospective multicenter study provides detailed information on TBI related variables of 508 moderate-severe TBI patients. Variability in epidemiology and outcome is examined by comparing our ...
Budic I - - 2011
Pneumatic tourniquets are widely used in pediatric extremity surgery to provide a bloodless field and facilitate dissection. This prospective study was carried out to examine possible effect of different anesthesia techniques on oxidative stress and endothelial dysfunction connected with ischemia-reperfusion injury during extremity operations at children's age. Patients were randomized ...
Tuncer Serhan - - 2011
The effects of piracetam on flap survival, ischemia-reperfusion (I/R) injury, and vascular endothelial growth factor (VEGF) expression were evaluated in this study. Unipedicled epigastric flap model was used in 36 rats and was evaluated within 4 groups. The flap was elevated and untreated in Group 1. Postoperative piracetam treatment was ...
Imberti R - - 2011
BACKGROUND:Surgery of spontaneous supratentorial intracerebral hemorrhage (ICH), especially if performed early, can be complicated by rebleeding, a condition that can worsen the outcome. We evaluated the effect of recombinant activated factor VII (rFVIIa) on postoperative rebleeding. METHODS:In this randomized, open-label, single-blinded study, 21 patients with spontaneous supratentorial ICH diagnosed by ...
Shaikh A K - - 2011
A randomized clinical trial was conducted to asses the effects of dexamethasone on brain oedema following acute ischemic stroke in the departments of Medicine of different hospitals from July, 2003 to December, 2006. A total of 60 patients were included in the study. They were divided into two groups keeping ...
Sobrino Tomás - - 2011
The increase in circulating endothelial progenitor cells (EPCs) is associated with a better outcome in patients with acute ischemic stroke. CDP-choline (citicoline) increases brain plasticity after experimental stroke. Therefore, we study if citicoline treatment could increase the EPC concentration after ischemic stroke. Forty-eight patients with a first-ever non-lacunar ischemic stroke ...
Tafreshi Gilda - - 2012
There is diurnal variation for cardiac arrest and sudden cardiac death. Stroke may show a similar pattern. We assessed whether strokes presenting during a particular time of day or night are more likely of vascular etiology. To compare emergency department stroke codes arriving between 22:00 and 8:00 hours (LuNAR strokes) ...
Brown Cathleen - - 2011
Background: Foot positioning before heel strike has been attributed to chronic ankle instability injury mechanics, and may play a role in developing and perpetuating chronic ankle instability. Purpose: This study was undertaken to determine if a group of individuals with mechanical instability (MI) or a group with functional instability (FI) ...
Simmons Matthew N - - 2011
PURPOSE: The percent of functional volume preservation is a primary determinant of functional outcome after partial nephrectomy. We assessed what is to our knowledge a novel method to estimate the percent of functional volume preservation to assess its effect on functional outcomes. MATERIALS AND METHODS: We studied the glomerular filtration ...
Faulkner Stuart S Institute for Women's Health, University College London, London, - - 2011
Additional treatments for therapeutic hypothermia are required to maximize neuroprotection for perinatal asphyxial encephalopathy. We assessed neuroprotective effects of combining inhaled xenon with therapeutic hypothermia after transient cerebral hypoxia-ischemia in a piglet model of perinatal asphyxia using magnetic resonance spectroscopy (MRS) biomarkers supported by immunohistochemistry. Thirty-six newborn piglets were randomized ...
Wind J - - 2011
BACKGROUND: Donation after cardiac death (DCD) expands the pool of donor kidneys, but is associated with warm ischaemic injury. Two methods are used to preserve kidneys from controlled DCD donors and reduce warm ischaemic injury: in situ preservation using a double-balloon triple-lumen catheter (DBTL) inserted via the femoral artery and ...
Deguchi I - - 2011
Background:  This study evaluated the usefulness of MR angiography (MRA)-diffusion-weighted imaging (DWI) mismatch in neuroendovascular therapy over 3 h after onset of acute cerebral infarction. Methods:  The subjects were 14 cases (age, 73 ± 8.4 years) who had an anterior circulation deficit on DWI/MRA on arrival and underwent neuroendovascular therapy over 3 h after onset. ...
Day Jason S - - 2011
Object Endovascular treatment of acute ischemic stroke delivers direct therapy at the site of an occluded cerebral artery and can be employed beyond the 3-4.5-hour window limit set for intravenous recombinant tissue plasminogen activator. In this paper, the authors report their experience with various endovascular therapies in acute ischemic stroke. ...
Ding Weiwei - - 2011
: Temporary intravascular shunts (TIVS) have been used as a damage control surgery (DCS) adjuncts in superior mesenteric artery (SMA) injuries, both experimentally and clinically. However, no study to date has evaluated the relationship between shunt indwelling time and resultant endothelial cell (EC) injury. We hypothesized that prolonged use of ...
Moharir Mahendranath D MD Division of Neurology, The Hospital for Sick Children, Toronto, Ontario, Canada. - - 2011
Neonatal cerebral sinovenous thrombosis is a frequent contributor to neonatal mortality and morbidity. Treatment is controversial, and reported clinical outcomes vary widely. Newborns with radiologically confirmed neonatal cerebral sinovenous thrombosis from 1992 to 2009 were prospectively followed in our Children's Stroke Clinic for standardized outcomes, including the Pediatric Stroke Outcome ...
Lemoine S - - 2011
Background: Remifentanil and sufentanil are widely used opioids during general anaesthesia for cardiac and non-cardiac surgery. This study was conducted to evaluate the hypothesis that the continuous administration of remifentanil and sufentanil, at clinically relevant concentrations, could provide protection of human myocardium, in vitro, against hypoxia-reoxygenation injury. Method: Isometrically contracting ...
Reichenberger Matthias A - - 2011
Enhancement of flap survival through extracorporeal shock wave treatment (ESWT) is a promising new technique; however, no attempt has been made to define the optimal time point and frequency of ESWT to optimize treatment with ESWT for ischemic indications. Twenty-eight male Wistar rats were randomized into 4 groups and an ...
Hwang Jinyoung - - 2011
OBJECTIVE:: The aim of this study was to investigate the effect of retrograde autologous priming (RAP) of the cardiopulmonary bypass (CPB) circuit on cerebral oxygenation. DESIGN:: A retrospective cohort study. SETTING:: A university hospital. PARTICIPANTS:: Ninety-four patients undergoing CPB. INTERVENTIONS:: CPB was primed with a RAP technique in the RAP ...
Zhang Caojin - - 2011
Aim: To evaluate the feasibility, safety and efficacy of the Spider™ patent foramen ovale (PFO) occluder for the treatment of PFOs in an animal model. Method: The foramen ovale was punctured to establish an animal model of a PFO. Under fluoroscopic guidance, the PFO was occluded with the Spider PFO ...
Rodríguez-Leor Oriol - - 2011
INTRODUCTION AND OBJECTIVES: In primary angioplasty, the interval between first medical contact (FMC) and reperfusion should be less than 120minutes. The time to reperfusion varies depending on where FMC is established. Recent studies suggest longer times in patients presenting in off-hours. The objective is to evaluate the time intervals between ...
Schöffl Volker - - 2011
OBJECTIVE:: Shoulder problems, especially SLAP (superior labral anterior-posterior) lesions, are frequent in rock climbers. Although various SLAP repair methods demonstrate 75% to 97% good functional outcomes in general population, the results in overhead athletes are inconsistent and the question whether a primary tenodesis is more efficient arises. DESIGN:: Prospective cohort ...
Le Duff Michel J - - 2011
The evolution of patient sporting activities after hip resurfacing has not yet been studied. A scoring algorithm to quantify sporting activity was developed to compare type of activity, frequency, duration, and overall activity level in the early postoperative period and at mid- to long-term follow-up. Quantification of sporting activity is a ...
Urabe Y - - 2011
Background Many athletes have foot deformity of hallux-valgus. These deformities lead to decrease of foot function and sports performance. The authors were developed a new device for decrease the angle of hallux-valgus. This device was socks and in use underwear in sports activity and daily living. Objective The purpose of ...
Ardern Clare L - - 2011
Background An athlete's intention to return to sport following anterior cruciate ligament (ACL) injury is a major indication for surgical intervention. Purpose The purpose of this review was to determine postoperative return-to-sport outcomes after ACL reconstruction surgery. Study design Meta-analysis and systematic review Methods Electronic databases including Medline, Embase, SPORTDiscus ...
Golant Alexander - - 2011
BACKGROUND: Shoulder arthroplasty has become more prevalent, and patients undergoing shoulder arthroplasty are becoming more active. Recommendations for return to athletic activity have not recently been updated and do not consider the newest arthroplasty options. METHODS: A survey was distributed to 310 members of the American Shoulder and Elbow Surgeons, ...
Cummins Justin S - - 2011
We studied National Trauma Data Bank data to determine the effectiveness of car safety devices in reducing mortality and injury severity in 184,992 patients between 1988 and 2004. Safety device variables were seat belt used plus air bag deployed; only seat belt used; only air bag deployed; and, as explicitly ...
Koca Kenan - - 2011
The aim of this study was to investigate the effects of ischemic preconditioning (IPC) and N-acetylcysteine (NAC) on oxidative stress resulting from tourniquet-induced ischemia-reperfusion (IR) period in arthroscopic knee surgery. Forty-five patients who had arthroscopic knee surgery for meniscal and chondral lesions and for pathologic medial plica were included in ...
Delise Pietro - - 2011
Frequent ventricular premature beats (VPBs) may be discovered during preparticipation screening in asymptomatic apparently healthy athletes. Some authors hypothesize that they may be a manifestation of 'athlete's heart' and suggest a deconditioning period, which should document a regression of arrhythmias, to exclude a concealed disease. To test this hypothesis, we ...
Ansari Saeed - - 2011
In recent years, endovascular self-expanding stents have become a viable option for neurointerventionalists treating acute ischemic stroke. Timely intervention for stroke could mean the difference between complete recovery and significant morbidity or death. Since 2006, a handful of clinical trials have demonstrated the potential of self-expanding stents in dependably achieving ...
Limtungturakul Sarawut - - 2011
We assessed the efficacy and safety of catheter directed thrombolysis in the patients with acute limb ischemia who have been treated with catheter directed thrombolysis. From the ACC/AHA 2005 Practice Guidelines for the Management of Patients with Peripheral Arterial Disease, Catheter-based thrombolysis is an effective and beneficial therapy and is ...
Namdari Surena - - 2011
Purpose: Females are at greater risk than males for sustaining an anterior cruciate ligament (ACL) tear. Performance outcomes and attrition rates associated with ACL injury and reconstruction in Women's National Basketball Association (WNBA) athletes are unclear. The purpose of this study was to compare athletes who underwent ACL reconstruction with ...
Genovese Eugenio - - 2011
PURPOSE: To compare morphological, power Doppler, and contrast-enhanced ultrasound (CEUS) features of the Achilles tendon between asymptomatic athletes and athletes who had undergone surgical repair of a previous rupture. METHODS: Twenty-four athletes were divided in two groups (A and B). Group A included 14 patients with a median age of ...
Hsu Wellington K - - 2011
BACKGROUND CONTEXT: Although clinical outcomes after lumbar disc herniations (LDHs) in the general population have been well studied, those in elite professional athletes have not. Because these athletes have different measures of success, studies on long-term outcomes in this patient population are necessary. PURPOSE: This study seeks to define the ...
Ricotti Leonardo - - 2011
Static balance in young athletes is an important ability that has a relevant influence on their present and future sport performances, as well as on the reduction in risk of injury. The present study reports data collected on three homogeneous groups of 9 years-old athletes (n=10 for each group), whose ...
Pradeep A R - - 2011
Background: A large amount of calculus may hamper the efficacy of daily oral hygiene and thereby accelerate plaque formation. Salivary concentrations of orthophosphate and pyrophosphate are important in preventing calculus formation. Activity of orthophosphate, pyrophosphate, and pyrophosphatase was studied in whole saliva in calculus-forming groups and plaque-forming groups. Methods: The ...
Kean Crystal O - - 2011
Prospective cohort with historical controls. To examine the effects of a 12-week preoperative high-intensity resistance training program on postoperative outcomes. The primary goals of high tibial osteotomy (HTO) are to decrease pain and improve overall function during activities of daily living and participation in sport and recreation in relatively young, ...
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