Search Results
Results 201 - 250 of 1559
< 1 2 3 4 5 6 7 8 9 10 >
Moldan Matthew M MM Department of Otolaryngology, University of Minnesota, Minneapolis, MN 55455, - - 2013
The epidermal growth factor pathway has been implicated in various tumors, including human papillomavirus (HPV) lesions such as recurrent respiratory papillomatosis (RRP). Due to the presence of epidermal growth factor receptors in RRP, epidermal growth factor receptor (EGFR) inhibitors have been utilized as adjuvant therapy. This case series examines the ...
Campochiaro Peter A PA Departments of Ophthalmology and Neuroscience, Johns Hopkins School of Medicine, Baltimore, Maryland 21287-9277, USA. - - 2013
Central retinal vein occlusion (CRVO) or branch retinal vein occlusion (BRVO) causes hypoperfusion, high levels of vascular endothelial growth factor (VEGF), macular edema, and loss of vision. Many patients also show areas of complete closure of retinal vessels (retinal nonperfusion [RNP]) that increase over time. The objective was to assess ...
Samra Mohamed Abu - - 2012
INTRODUCTION: The human oropharynx and nasopharynx are home of different bacteria and fungi. The initial sterile endotracheal tube (ETT) transfers mechanically the bacteria from the nasopharynx and oropharynx to the sterile tracheobronchial tree. We investigated the efficacy of Neomycin-Bacitracin combination spray in the prevention of this bacterial translocation through its ...
Ozlü Ferda - - 2012
Exposure to parenteral nutrition (PN) is one major factor in the development of cholestasis. The aim of this retrospective study was to compare the effect of these two different PN regimens on PN associated cholestasis. The files of the patients who have received different PN regimens for > 14 days ...
Cha Soo-Min - - 2012
To determine the amount of shortening needed in an ulna to achieve final neutral ulnar variance in adolescents with ulnar impaction syndrome. Radiological and clinical outcomes were evaluated after ulnar shortening and after growth had stopped. From February 2006 to February 2009, we prospectively followed 16 consecutive patients treated with ...
Lou Zhengcai - - 2012
OBJECTIVE: The goal of this study was to evaluate the effects of conservative treatment and fibroblast growth factor (FGF) applied directly or via Gelfoam on the healing of large traumatic tympanic membrane perforations (TMPs) in humans. STUDY DESIGN: Prospective, randomized, controlled trial. METHODS: A randomized prospective analysis was performed between ...
Thakare Kaustubh - - 2012
Increased knowledge of specific cellular responses and functions has led to the development of numerous treatment modalities based on the use of growth factors. This controlled clinical and radiographic study aimed to evaluate the effectiveness of recombinant human platelet-derived growth factor BB (rhPDGF-BB) + Β?tricalcium phosphate (Β-TCP) in the treatment ...
Sanpera Ignacio I - - 2012
: During the last few years, the use of the 8-plate as a technique for hemiepiphysiodesis has gained wide acceptance, as it has been shown that it works in a more physiological way than other methods such as staples or transphyseal screws. It has mechanically been compared with a tension ...
Lafzi Ardeshir - - 2012
The aim of this study was to evaluate the clinical efficiency of the subepithelial connective tissue graft (SCTG) with and without plasma rich in growth factor (PRGF) in the treatment of gingival recessions. Twenty bilateral buccal gingival Miller's Class I and II recessions were selected. Ten of the recessions were ...
Soliman A A Cairo University, Cairo, Egypt. - - 2012
This double-blind trial followed 16 patients with autosomal dominant polycystic kidney disease (ADPKD) who received telmisartan or sirolimus plus telmisartan for 24 months. The 6-month pilot study showed a promising effect of sirolimus. The primary metric of this 2-year study was the change in total kidney volume at 12 and ...
Qin Jian - - 2012
The aim of the present study was to observe the effects of gene‑activated matrix (GAM) on autograft healing of the anterior cruciate ligament. Forty‑eight rabbits were randomly divided into groups A and B. Rabbits were used to construct models of anterior cruciate ligament reconstruction. In group A, transforming growth factor (TGF)‑β1 was ...
Vavken Patrick P Sports Medicine Research Laboratory, Department of Orthopedic Surgery, Children's Hospital Boston, Harvard Medical School, Massachusetts, USA. - - 2013
The objective of this study was to assess the effect of absorbable or nonabsorbable sutures in bioenhanced anterior cruciate ligament (ACL) repair in a skeletally immature pig model on suture tunnel and growth plate healing and biomechanical outcomes. Sixteen female skeletally immature Yorkshire pigs were randomly allocated to receive unilateral, ...
Delmo Walter Eva Maria - - 2012
BACKGROUND: The degree of involvement of left ventricular inflow tract obstruction is the predominant factor determining outcome in Shone's anomaly. In this series of patients with Shone's anomaly, we evaluated the impact of mitral valve (MV) repair strategies performed to correct the components of this anomaly on growth of the ...
Brzana Jessica - - 2012
Acromegaly is associated with serious morbidity and mortality, if not well controlled. Approved somatostatin receptor ligands (SRLs) are a mainstay of medical therapy and exhibit preferential affinity for somatostatin receptor (SSTR) subtype 2. Our objective was to assess whether characteristic features of individual growth hormone (GH)-secreting adenomas at diagnosis, correlated ...
Yao Min - - 2012
Non contact low frequency ultrasound (NCLF-US) devices have been increasingly used for the treatment of chronic non healing wounds. The appropriate dose for NCLF-US is still in debate. The aims of this pilot study were to evaluate the relationship between dose and duration of treatment for subjects with non healing ...
Kim Kyung Im - - 2012
Oral mucositis (OM) is one of the most common and debilitating complications in patients undergoing intensive chemotherapy followed by hematopoietic stem cell transplantation (HSCT). The aim of this study was to evaluate the efficacy and safety of recombinant human epidermal growth factor (rhEGF) oral spray for OM induced by intensive ...
Le Gloan Laurianne - - 2012
BACKGROUND: Many adults with repaired tetralogy of Fallot have had prior Blalock-Taussig shunts. These shunts may theoretically hinder growth and development of the ipsilateral arm. METHODS: We prospectively enrolled consecutive patients with tetralogy of Fallot in a cross-sectional study to measure arm length and assess handgrip strength. Bilateral handgrip strength ...
Fadel Bahaa M - - 2012
OBJECTIVES: In children with aortic valve disease associated with annular hypoplasia or complex multilevel left ventricular outflow tract obstruction, the Ross procedure, combined with a modified Konno-type aortoventriculoplasty, is advocated. We aim to examine the fate of the neoaortic apparatus and assess neoaortic valve function after the modified Ross-Konno procedure. ...
Sekaran P - - 2012
PURPOSE: Proximal hypospadias represents 20% of hypospadias cases and are considered to have a higher incidence of associated urological, non-urological, developmental, Disorders of Sex Development and chromosomal anomalies. The aim of this study was to compare the occurrence of associated anomalies in boys with proximal hypospadias and undescended testis with ...
Xie Xiaoxing - - 2012
BACKGROUND: Autologous platelet-rich plasma (PRP) has been investigated as a potential promoter of tendon healing and has an enhancing effect on the anterior cruciate ligament (ACL) graft maturation process. However, the influence of PRP on the synthesis and degradation of the extracellular matrix during the ACL graft remodeling process has ...
Son Su-Min - - 2012
BACKGROUND: Epiphyseal stapling has been widely used to correct angular deformity. The mechanism, however, has not been well determined. To determine the effect of temporary hemiepiphyseal stapling on the cellular layers of the physis, a histomorphometric study was performed using immature rabbits. METHODS: Distal lateral epiphyseal stapling of the right ...
Yao Yu-Chang - - 2012
Cryopreservation has been widely utilized in livestock and human embryos, which allows for storage of worthy embryos for a long period of time, although it is still uncertain as how long embryos can be cryopreserved in liquid nitrogen. The aims of this study were to evaluate the effects of long-term ...
Spoel Marjolein - - 2012
Respiratory morbidity has been described in patients who underwent repair of esophageal atresia as a neonate. We compared the influence of open thoracotomy or thoracoscopy on lung function, respiratory symptoms, and growth. Functional residual capacity (FRC(p)), indicative of lung volume, and maximal expiratory flow at functional residual capacity (V'max(FRC)), indicative ...
Sancho Juan J - - 2012
: To assess the immediate and long-term clinical results of 2 different surgical procedures for the treatment of asymmetrical multinodular goiter (AMG). : Half of the patients presenting with a single benign thyroid nodule have contralateral subclinical disease. There is a controversy whether these patients should be treated with hemithyroidectomy ...
Manosudprasit Montian - - 2012
The intended aim of treatment in cleft lip and palate patients with growth modification is to improve the relation of jaws by advance the maxilla, restrict the mandible or combination of these. The appliances usually used are face mask or protraction headgear (Delaire and Petit types). Modification of growth is ...
Nørholt S E - - 2012
In juvenile idiopathic arthritis (JIA), temporomandibular joint involvement is a frequent complication leading to deficient mandibular growth. Occurring unilaterally this will give rise to mandibular and maxillary asymmetry that will affect the soft tissue and the muscles and result in complex dentofacial anomaly. In the case of severe dentofacial malformation, ...
Akbarnia Behrooz A - - 2012
ABSTRACT: Study Design: Prospective non-randomized study.Objective: To report the preliminary results of Magnetically Controlled Growing Rod (MCGR) technique in children with progressive early onset scoliosis (EOS).Summary of Background Data: Growing rod (GR) technique is a viable alternative for treatment of EOS. High complication rate is attributed to frequent surgical lengthening. ...
Baulesh David M - - 2012
: Serial casting has demonstrated efficacy for idiopathic early-onset scoliosis (EOS). Results of casting in nonidiopathic (syndromic and congenital) EOS patients have not previously been well described. : A total of 53 patients underwent serial casting for EOS from 2005 to 2010 at a single institution. Deformity was classified as ...
Ugburo Andrew O - - 2012
Abstract Giant fibroadenoma (GFA) may present with breast asymmetry and can be excised with an inframammary incision (IFI) or reduction mammoplasty incision (RMI). This study investigated the clinical presentation and compared excision with the IFI and RMI. All patients with benign breast tumours greater than 5 cm underwent core needle ...
Kraus Tanja - - 2012
In skeletally immature patients, surgical options due to recurrent patella dislocation are limited, because bony procedures bear the risk of growth disturbances. In this retrospective study, we report the long-term functional and radiographic outcome in skeletally immature patients using the modified Grammont surgical technique. Between 1999 and 2004, 65 skeletally ...
Chen Zhi - - 2012
PURPOSE: To compare axial elongation between myopic orthokeratology (OK) contact lens and spectacle wearers, and to investigate the impact of pupil diameter on axial growth in myopic children after OK treatment. METHODS: Fifty-two Chinese children aged 9 to 14 years were enrolled in this study, 27 for the OK group ...
Raluy-Collado David - - 2012
BACKGROUND: The appearance of the 8-plate as a method for hemiepiphysiodesis has renewed the interest for the use of this technique. However, many questions remain unanswered about the way of action of the guided growth method. Although screw length has been said to play no role, to our knowledge, no ...
Lou Zhengcai - - 2012
OBJECTIVE: The goal of this study was to evaluate the effects of conservative treatment and fibroblast growth factor (FGF) applied directly or via Gelfoam on the healing of large traumatic tympanic membrane perforations (TMPs) in humans. STUDY DESIGN: Prospective, randomized, controlled trial. METHODS: A randomized prospective analysis was performed between ...
Gallego Patricia - - 2012
PURPOSE: To determine the effects of intravitreal atropine on scleral growth in the form-deprived chick as an experimental model of myopia. METHODS: Five groups of five chicks were studied from day 0-12 post-hatching. One group remained untreated (C), and four were form-deprived by monocular light diffusers to induce myopia. Two ...
Koh Mark Jean-Aan - - 2012
  We present the case of a 5-year-old boy who presented with systematized epidermal nevus with evidence of epidermolytic hyperkeratosis on skin biopsy. He was otherwise well, with normal growth and development and no evidence of other organ system involvement. He had experienced only mild improvement with potent topical corticosteroids. ...
Fayazzadeh Ehsan - - 2012
Impaired wound healing in ischemic tissues such as skin flaps resulting from inefficient perfusion is one major cause of complications in plastic surgery. In present experimental study, we investigated the effects of fibroblast growth factor-2 (FGF-2 or bFGF) and erythropoietin (EPO) in prevention of skin flap necrosis in rats. 30 ...
Gunel Ugur - - 2012
AIM: The aim of this prospective study was to evaluate the outcome of open reduction and Tönnis acetabuloplasty as the first method of treating developmental dysplasia of the hip (DDH) in children in early childhood at walking age. MATERIALS AND METHODS: Between 2005 and 2009, 34 hips of 34 children ...
Gubitosi Adelmo - - 2012
A 62 y.o. male with tight fimosis, swelling, redness, pain on palpating and necrosis of the penis and scrotum was admitted in our clinic, (FGSI = 6) with periferic vasculopathy; and diabetes mellitus type II and he was in dialysis treatment before the hospitalization. The patient was HCV affected. In ...
Oznurlu Y - - 2012
Detrimental effects of aflatoxin B(1) (AFB(1)) on the embryonic development of broiler tibia and its proximal growth plate were determined by means of histological, histometric and immunohistochemical methods. For this, 420 fertile eggs from parent stocks of Ross 308 broiler chickens were divided into five groups according to the proposed ...
Friedrich Colin - - 2012
OBJECTIVES/HYPOTHESIS: Intraoperative neuromonitoring (IONM) facilitates recurrent laryngeal nerve (RLN) identification, but various studies affirm virtually unchanged postoperative RLN palsy rates. Several authors meanwhile suggest continuous intraoperative neuromonitoring (CIONM) via vagal nerve stimulation (VNS) to improve RLN protection. However, knowledge of side effects of electrical VNS derives mainly from its therapeutic ...
Tajima Masaaki - - 2012
Mechanical stapling for colorectal anastomosis is popular, but the safety of its use for anastomosis in peritonitis is unclear. We evaluated the safety and effectiveness of mechanically stapled vs. hand-sutured anastomosis by comparing wound healing in an animal model of bacterial peritonitis. Male Sprague-Dawley (n=48) rats underwent cecal ligation and ...
Bonafede Machaon - - 2012
Tumor necrosis factor (TNF)-blockers are approved for use in several immune-related conditions, but treatment patterns, such as switching between TNF blockers or restarting treatment after a gap in therapy, are not clearly established. This analysis examined TNF blocker treatment patterns within the first year after initiating treatment with etanercept, adalimumab, ...
Yang Cheng-Tao - - 2012
The aim of this retrospective study was to examine the predictors of discontinuation of anti-tumor necrosis factor (TNF) therapy due to adverse events in Chinese patients with rheumatoid arthritis (RA). Anti-TNF-related adverse events were recorded and analyzed in 217 consecutive patients with RA followed in our institution from 2003 to ...
Mantovani Talita Rafaele D'Agostini - - 2012
Alternative substrates for cryopreservation at -20 °C have been little explored for basidiomycetes and could bring new possibilities of lower cost cryopreservation. Nevertheless, freezing temperatures between -15 and -60 °C are very challenging because they frequently result in cryoinjuries. The objective of this study was to evaluate substrates associated to cryoprotective agents ...
Atzeni Fabiola - - 2012
To evaluate the risk of serious infections (SIs) in RA patients receiving anti-TNF therapy on the basis of the data included in the GISEA register. The study involved 2769 adult patients with long-standing RA (mean age 53.2±13.4 years; mean disease duration 9.0±8.3 years) enrolled in the GISEA register, who had ...
El-Markaby Hussein S - - 2012
PURPOSE:: The aim of this study was to describe cases with severe acute posterior multifocal placoid pigment epitheliopathy treated with tumor necrosis factor (TNF) blocker [Remicade (infliximab)] as regards the improvement of visual acuity, contralateral affection, and prevention of recurrence. METHODS:: We analyzed patients with severe acute posterior multifocal placoid ...
Paccou Julien - - 2012
While remission is possible in patients with ankylosing spondylitis (AS), it is often unclear what attitude should be adopted once remission has occurred. We investigated whether dosage adjustment is an effective means of maintaining remission. This was a retrospective study drawn from clinical situations. Remission was defined using clinical measures ...
Yan Jiun-Lin - - 2013
Radiotherapy is a crucial treatment for acromegalic patients with growth hormone (GH)-secreting pituitary tumors. However, its effect takes time. We retrospectively reviewed the long-term outcome of linear accelerator stereotactic radiosurgery (LINAC SRS) for patients with acromegaly from the perspective of biochemical remission and associated factors. Twenty-two patients presenting with residual ...
Crispim Cibele Aparecida - - 2012
Shiftwork is often associated with metabolic diseases, and in the past few years, several cytokines have been postulated to contribute to various diseases, including insulin resistance. The aim of this study was to compare the concentrations of adiponectin, tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6) in samples of young adult ...
Beck-Peccoz Paolo - - 2012
To describe the rationale and design of PATRO Adults, a postmarketing surveillance study of the long-term efficacy and safety of somatropin (Omnitrope(®)) for the treatment of adult patients with growth hormone deficiency (GHD). PATRO Adults is an observational, multicentre, open, longitudinal, noninterventional study being conducted in hospitals and specialized endocrinology ...
< 1 2 3 4 5 6 7 8 9 10 >