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Xiao Zhibo - - 2013
: Excessive collagen deposition causes hypertrophic scarring after dermal wound repair. It can be functionally and cosmetically debilitating to many patients. A direct approach to the control of scar tissue formation is pharmacological regulation of collagen synthesis and deposition. Some studies reported that hepatocyte growth factor (HGF) plays an important ...
Nelson Danielle - - 2013
Abstract Androgen replacement therapy for male hypogonadism may be prescribed utilizing intramuscular, oral or more recently, topical formulations. With topical formulations, there is a risk of person-to-person transmission if appropriate precautions are not taken. We describe two cases of virilization in pre-pubertal children following passive transfer of paternal topical testosterone. ...
Adas Gokhan G Department of Surgery, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, 34147 Istanbul, - - 2013
To investigate the role of growth hormone (GH), hyperbaric oxygen therapy (HBOT) and combined therapy on the intestinal neomucosa formation of the gastric serosa. Forty-eight male Wistar-albino rats, weighing 250-280 g, were used in this study. The rats were divided into four groups (n = 12): Group 1, control, gastric ...
Tolenaar Jip L - - 2013
BACKGROUND: Aortic growth rate in acute type B aortic dissection (ABAD) is a significant predictor for aortic complications and death. To improve the overall outcome, radiologic predictors might stratify patients who benefit from successful medical management vs those who require intervention. This study investigated whether the number of identifiable entry ...
Doro Daniele - - 2013
PURPOSE: To report the outcomes of choroidal nevi monitoring and to compare the detection of ultrasonographic hollowness, a risk factor of malignant transformation, from a B-scan with results from an A-scan examination. DESIGN: Retrospective cohort study. METHODS: Standardized A- and B-scan echography and ophthalmoscopy in 358 consecutive patients with median ...
Tsovolou Eirini-Charikleia - - 2013
Evidence from a recent randomized study of our group suggests that intravenous clarithromycin resulted in earlier resolution of ventilator-associated pneumonia. The need to understand the mechanism of action of clarithromycin guided to the study of a model of experimental empyema by multidrug-resistant Pseudomonas aeruginosa in 40 rabbits. Animals were randomized ...
Pendleton Albert Martin - - 2013
The purpose of this study was to evaluate the effectiveness and complication rate of guided growth for the treatment of patients with a moderate leg-length discrepancy. The authors retrospectively reviewed all patients treated with guided growth for a moderate leg-length discrepancy at their institution between October 2004 and December 2010. ...
Kuang Anna A - - 2013
Whether cranial vault remodeling surgery for nonsyndromic, isolated sagittal suture synostosis affects the patency of initially normal, unaffected sutures is unknown. The influence of coronal and lambdoidal suture patency after cranial vault remodeling on the trajectory of subsequent cranial growth is also unknown. Disruption of normal sutural anatomy during cranial ...
Sulu Barlas - - 2013
Shark cartilage has anti-inflammatory, analgesic, anti-angiogenic, anti-tumoral, and immunomodulatory properties. We studied the effect of shark cartilage on the healing of colonic anastomoses, which are among the gastrointestinal system anastomoses that most commonly cause leakage. Rabbits were divided into two groups of seven as the study and control groups. A ...
Kulkarni Atul P - - 2013
Infectious complications of invasive procedures affect patient outcomes adversely. Choice of antiseptic solution at the time of insertion is one of the major factors affecting their incidence. This study was undertaken to compare efficacy of chlorhexidine 2% and povidone iodine 10% for skin disinfection prior to placement of epidural and ...
Koh In Jun IJ Department of Orthopaedic Surgery, Uijeongbu St Mary's Hospital, Gyunggido, - - 2013
The use of total knee arthroplasty (TKA) has increased substantially in most Western countries. However, the trends in TKA use and changes in demographic characteristics of patients having TKA in Korea remain unclear. We documented the trends in TKA use and in the demographics of patients undergoing TKA in Korea ...
Chen Jing J Department of Ophthalmology, Guangzhou General Hospital of Guangzhou Command, Guangzhou, China. - - 2013
To observe the influence of flap-on or flap-off Epipolis laser in situ keratomileusis (epi-LASIK) on the release of transforming growth factor-β1 (TGF-β1) in tear fluid and corneal haze formation. Thirty patients (60 eyes) with myopia underwent epi-LASIK surgery with epithelial flap repositioning (flap-on) in the right eyes and epithelial flap ...
Driscoll Matthew M Scott and White Memorial Hospital, Temple, TX, - - 2013
Ankle valgus is encountered in children with a variety of congenital musculoskeletal disorders, including multiple hereditary exostoses (MHE). Guided growth with temporary distal tibial medial hemiepiphysiodesis (DTMH) may correct the deformity; however, exostoses about the ankle commonly observed in MHE patients may hinder correction and increase the risk of recurrence. ...
Lykissas Marios G - - 2013
The purpose of this study was to compare the safety and effectiveness of three mechanical devices (percutaneous transphyseal screws, tension band plates, and staples) for the correction of limb length discrepancies in growing children and adolescents. Thirty-nine consecutive patients treated with epiphysiodesis for limb length discrepancy were retrospectively reviewed. No ...
Hangge Patrick T PT Division of Cardiology, The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, - - 2013
Hypoplastic left heart syndrome (HLHS) is associated with significant mortality and morbidity. Fetal head growth abnormalities have been identified in a subset of HLHS fetuses, but it is unclear whether specific patterns of maladaptive growth affect clinical outcomes. We hypothesized that poor fetal head growth is associated with an increased ...
Appelman N - - 2013
BackgroundThe beneficial effects of recombinant human growth hormone (rhGH) therapy in growth hormone deficient (GHD) adults are well-established in the short-term. However, data documenting the effects during prolonged follow-up are relatively scarce.ObjectiveTo evaluate the reported effects of rhGH replacement (≥5 years) in GHD adults on biochemical and anthropometric parameters, quality ...
Sharma Richa - - 2013
Aim: To assess if residual drops of unims can be used after single use to cut down economic load. Setting: Laboratory setting. Materials and Methods: This study was done to determine the possibility of multi-use of such unims. Ten unims of Acuvail (ketorolac tromethamine 0.45%) were opened simultaneously to culture ...
Uhlman Matthew A - - 2013
The incidence of small renal masses (≤ 4 cm) has increased over the past three decades. Partial nephrectomy remains the standard for treatment of such lesions, but increased attention is being given to patients who may benefit from active surveillance, given the low risk of metastatic spread and traditionally slow ...
Doucet Jean-Charles - - 2013
PURPOSE: The objective was to analyze the effects of growth on the long-term result of maxillary distraction osteogenesis (DO) in cleft lip and palate (CLP). PATIENTS AND METHODS: Retrospective study of 24 CLP cases with long-term follow-up operated for maxillary DO using the Polley and Figueroa technique: 10 patients were ...
Dhingra Rajan - - 2013
OBJECTIVES: This study aimed to determine the effect of antioxidant (AO) supplementation on surrogate markers of fibrosis in patients with chronic pancreatitis (CP). METHODS: In a randomized, placebo (PL)-controlled trial, patients with CP were randomized to groups that were given PL or AO for 3 months. Outcome measures were change ...
Barutca Seda Asfuroğlu - - 2013
BACKGROUND: The long-term goal of cleft palate repair is to provide normal maxillary growth and speech capacity. However, most surgical repairs of cleft palate result in areas of bone denudation on lateral aspects of the hard palate. It is widely acknowledged that palatal bone denudation and subsequent scar contracture resulting ...
Maas Matthew B - - 2013
To evaluate the incidence, characteristics, and clinical consequences of delayed intraventricular hemorrhage (dIVH). Patients with primary intracerebral hemorrhage (ICH) were enrolled into a prospective registry between December 2006 and February 2012. Patients were managed, and serial neuroimaging obtained, per a structured protocol. Initial and delayed IVH were identified on imaging, ...
Moursy Essam ElDin S EE Urology Department, Sohag Faculty of Medicine, Sohag, Egypt. Electronic address: - - 2013
To evaluate outcomes of adolescent varicocele in the case of surgical versus conservative management. 173 adolescent patients presenting with varicocele were evaluated clinically and sonographically to define varicocele grade and testicular volume. The patients were divided into 2 groups: A (53) with testicular size discrepancy >20% and bilateral varicoceles; B ...
Moal Bertrand B NYU Hospital for Joint Diseases, 306 E. 15th St, Suite 1F, New York, NY 10003, - - 2013
Non-fusion treatment for adolescent idiopathic scoliosis generates interest due to the potential for growth preservation and mobility. Using an established porcine scoliotic model, this study aims to evaluate the global alignment and the morphology of the spine with and without application of a non-fusion corrective tether. At 12 weeks of ...
Kemp Anna - - 2013
PURPOSE:: To determine the risk of thromboembolic and gastrointestinal bleeding events in the 12 months after injections of bevacizumab or ranibizumab compared with photodynamic therapy and a nontreated community sample. METHODS:: Hospital and death records were examined for 1,267 patients treated with vascular endothelial growth factor inhibitor and 399 patients ...
Rizkala Emad - - 2013
OBJECTIVE: To assess the long-term occurrence of hydroceles and varicocele recurrence in patients receiving lymphatic sparing laparoscopic varicocelectomy (LSLV) compared to those receiving plain laparoscopic varicocelectomy (PLV), and also to assess the growth of testicular volume postoperatively. METHODS: We employed a standard three-trocar configuration. The spermatic vessels were identified in ...
Xu Yi - - 2013
The aim of this study was to analyze the accurate three-dimensional positions and positional changes of the lip and nose in patients with unilateral cleft lip and palate. Sixty-three patients with unilateral complete cleft lip and palate (UCLP) and 96 patients with isolated cleft palate were retrospectively enrolled. Facial casts ...
Kar Bikash Ranjan - - 2013
Nevus depigmentosus is a congenital hypomelanotic condition for which no effective treatments are available. The hypopigmentation is permanent and enlarges in proportion with growth in the person. Here, I report a patient of nevus depigmentosus on whom we performed suction blister grafting and the resultant pigmentation was satisfactory even at ...
Latalski Michał - - 2013
Introduction. The aim of treating children with early onset scoliosis is to guide the growth of the spine until the patients reach skeletal maturity. Regardless of its aetiology, progressive early-onset scoliosis requires multiple-stage surgery, usually at 6 to 12 months' intervals. However, precise coordination of the timing of each consecutive ...
Buonocore Daniela - - 2013
Androgenetic alopecia (AGA) is the most common cause of hair loss among males, characterized by progressive thinning of the scalp hairs and defined by various patterns. The main factors underling hair loss in AGA are genetic predisposition and increased sensitivity of the hair follicles to androgens, leading to a shortening ...
Nadjmi N - - 2013
A two-stage palatal repair using a modification of Furlow palatoplasty is presented. The authors investigate the speech outcome, fistula formation and maxillary growth. In a prospective, successive cohort study, 40 nonsyndromic patients with wide cleft palate were operated on between March 2001 and June 2006 by a single surgeon. 10 ...
Fodor Mariann - - 2013
OBJECTIVES:: The release of different cytokines and mediators in tears of patients with keratoconus (KC) wearing contact lenses (CLs) may contribute to the pathology of KC. METHODS:: Cohort study was established in patients with KC wearing rigid gas permeable (RGP) CL (group I), patients with ametropia wearing silicone hydrogel (Si-Hi) ...
Mets Joseph M - - 2013
BACKGROUND: FACTORS ASSOCIATED WITH OBSTRUCTION OF THE CAVOPULMONARY PATHWAY IN PATIENTS WITH A LATERAL TUNNEL (LT) INTRACARDIAC FONTAN CONNECTION AND OUTCOMES OF PERCUTANEOUS STENT IMPLANTATION FOR THIS COMPLICATION HAVE NOT BEEN CHARACTERIZED.METHODS AND RESULTS: BETWEEN 1999 AND 2011, 51 PATIENTS UNDERWENT STENT IMPLANTATION FOR LT PATHWAY STENOSIS AT A MEDIAN ...
Fernández-Sarmiento J Andrés - - 2013
The use of plasma rich in growth factors (PRGF) has been proposed to improve the healing of Achilles tendon injuries, but there is debate about the effectiveness of this therapy. The objective of the present study was to evaluate the histological effects of PRGF, which is a type of leukocyte-poor ...
Ralls Matthew W MW Section of Pediatric Surgery, Department of Surgery and the C.S, Mott Children's Hospital, University of Michigan, 1540 E. Hospital Dr., SPC 4211, Ann Arbor, MI 48109-4211, - - 2013
Distraction-induced intestinal growth may be a novel treatment for short bowel syndrome. Longitudinal, distractive tension created by the application of force creates a significant challenge: to produce adequate force, yet not cause perforation at the fixation points. This paper describes our development of a coupling strategy to allow for successful ...
Abouammoh Marwan A - - 2013
To study the effect of intravitreal ranibizumab on idiopathic epiretinal membranes (ERMs). A retrospective cohort study on a consecutive series of ranibizumab intravitreal injections for epiretinal membranes was performed. Four cases were identified by reviewing a claims database linked to electronic medical records. All patients received a total of three ...
Xie Xiaoxing X Department of Arthroscopic Surgery, Sixth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, - - 2013
Autologous platelet-rich plasma (PRP) has been investigated as a potential promoter of tendon healing that affects the anterior cruciate ligament (ACL) graft maturation process. However, the influence of PRP on revascularization and reinnervation during the ACL graft remodeling has never been investigated. We randomly assigned healthy and mature beagles to ...
Brunocilla Eugenio - - 2013
PURPOSE: To provide our experience with active surveillance in patients incidentally diagnosed with small renal masses and show the results of long-term follow-up. PATIENTS AND METHODS: We retrospectively evaluated a cohort of 42 patients diagnosed with small renal mass (≤4 cm in diameter). All patients had clinical and radiological follow-up every ...
Salah Nermin - - 2013
Abstract Objective: To study growth response to growth hormone (GH) treatment in growth hormone-deficient (GHD) patients. Patients and methods: In total, 477 GHD children were included in the study. Patients were followed up for a minimum of 1 year and up to 6 years, anthropometric assessment was performed every 3 ...
Metzler Philipp - - 2013
Fronto-orbital advancement (FOA) is the most common technique used to correct plagiocephaly and trigonocephaly. The aim of this study was to investigate the cranial vault growth following FOA and to compare the growth pattern to the normal standard. Fifty-two Swiss children (25 with anterior plagiocephaly and 27 with trigonocephaly) between ...
Seery Thomas J - - 2013
OBJECTIVE: The aim of this study was to analyze our experience with the cryopreserved femoral vein homograft in comparison with standard biomaterials for neoaortic reconstruction in the Norwood stage 1 operation. METHODS: All patients who underwent the Norwood operation from September 2004 to April 2011 were analyzed retrospectively (n = 107). Patients ...
Gubitosi Adelmo - - 2013
A 62 y.o. male with tight fimosis, swelling, redness, pain on palpating and necrosis of the penis and scrotum was admitted in our clinic, (FGSI = 6) with periferic vasculopathy; and diabetes mellitus type II and he was in dialysis treatment before the hospitalization. The patient was HCV affected. In ...
Kumar Sharanya Ajit - - 2013
Aim: The aim of this study was to determine any skeletal morphologic features evident on a pretreatment lateral cephalogram that may be used to predict improvement in the sagittal relationship during functional appliance therapy in Class II patients and compare changes between cases with and without a favorable response to ...
Rubins Robert P - - 2013
Gingival recession is a challenging defect for clinicians to treat effectively. A number of recent systematic reviews have identified the connective tissue graft (CTG) in combination with coronally advanced flaps (CAFs) as the most consistently effective treatment for Miller Class I and II defects across all outcome measures. Recent advances ...
Kömür Baran - - 2013
The aim of this study was to compare the Phemister technique (permanent epiphysiodesis) with temporary epiphysiodesis with stapling and evaluate the degree of epiphyseal plate activity following staple removal using radiographic, scintigraphic and histopathologic methods and to investigate whether bone scintigraphy could provide clues on expected physis activity. This study ...
Tee Meng Hun - - 2013
We studied asymptomatic primary schoolchildren in northeastern Malaysia with light to moderate trichuriasis to determine the effect of albendazole treatment on growth rates and TNF-alpha levels. Thirty-seven schoolchildren aged 6-7 years with stool samples positive for Trichuris trichiura and negative for other geohelminths and protozoa were randomized to receive albendazole ...
Liu Huihui - - 2013
Resina Draconis (RD) is a type of dragon's blood resin obtained from Dracaena cochinchinensis (Lour.) S.C. Chen (Yunnan, China). It has been used as a medicine since ancient times by many cultures. The ethanolic extract of Resina Draconis (RDEE) was evaluated for its wound-healing activity using excision and incision wound ...
Oltramari-Navarro Paula Vanessa Pedron - - 2013
Skeletal Class III malocclusion, with its unpredictable and unfavorable nature, has been characterized by a growth pattern with doubtful prognosis regarding orthodontic mechanics, even when performed early. For a long time, Class III malocclusion was regarded as a synonym of mandibular prognathism, regardless of the affected skeletal structures. Mandibular growth, ...
Christoforidis John B - - 2013
To investigate the effect of intravitreal bevacizumab and ranibizumab on wound tension and by histopathology during cutaneous wound healing in a rabbit model and to compare this effect to placebo intravitreal saline controls 1 and 2 weeks following intravitreal injection. A total of 120 New Zealand white rabbits were randomly ...
Ruiz-Moneo Pedro - - 2013
The aim of this study was to determine whether addition of plasma rich in growth factors (PRGF) improves functional and structural outcomes after arthroscopic repair of full-thickness rotator cuff tears. The study design was independent (investigator-sponsored), randomized in parallel groups, double-blind, and controlled with a conventional surgical technique clinical trial. ...
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