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Taggart David P DP Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Oxford, UK - - 2014
The Arterial Revascularization Trial (ART) is a randomized comparison of bilateral internal mammary artery (BIMA) versus single internal mammary artery (SIMA) grafting in coronary artery bypass graft (CABG) surgery and is one of the largest randomized trials of surgery ever conducted. ART is also one of the largest studies of ...
Talha Ahmed A Department of Surgery, Medical Research Institute, Alexandria University, Alexandria, - - 2014
This study was designed to compare the surgical outcomes of haemorrhoidectomy performed by the Ligasure, Harmonic Scalpel with that performed by the conventional diathermy. A total of 180 patients were randomized to Ligasure, Harmonic Scalpel and diathermy haemorrhoidectomy, 60 patients for each group. The operative time, post-operative pain scores, parenteral ...
- - 2014
This study was designed to evaluate the safety and efficacy of a novel, self? cross-linked hyaluronic acid (HA) hydrogel compared with carboxymethylcellulose (CMC) viscous foam in promoting healing when applied after ethmoidectomy. A prospective, randomized, controlled, blinded clinical trial was performed. The study was performed by four surgeons operating in ...
Nelson E Andrea EA School of Healthcare, University of Leeds, Baines Wing, Leeds, UK, LS2 - - 2014
Up to 1% of adults will have a leg ulcer at some time. The majority of leg ulcers are venous in origin and are caused by high pressure in the veins due to blockage or weakness of the valves in the veins of the leg. Prevention and treatment of venous ...
Zölß Christoph C Ambulatorien der Steiermärkischen Gebietskrankenkasse, Fachärztezentrum Graz, Graz, - - 2014
Chronic wounds represent a large and growing segment of health care and add considerably to human suffering and economic burden as populations age. More effective materials, especially those promoting ease of use and economy, are needed to treat this increasing number of patients. A case series conducted at a European ...
Boggio Ricardo Frota RF Department of Cell and Development Biology, Institute of Biomedical Science, University of São Paulo, Av. Prof. Lineu Prestes, 1524, ICB I rooms 306/307, Butantan, São Paulo, SP, 05508-900, Brazil, - - 2014
Skin injuries and the consequent loss of tissue integrity triggers a sequence of cellular and biochemical events that lead to a healed wound. Any failure during this rather sophisticated process may result in pathological scarring. To evaluate the efficacy of topical verapamil as a modulator of the healing process, a ...
Bohn Gregory A GA Gregory A. Bohn, MD, FACS, is Medical Director, The Center for Wound and Hyperbaric Medicine at West Shore Medical Center, Manistee, Michigan. Kimberly Gass, RN, is a Nurse, Trinity Wound Center for Wound and Hyperbaric Medicine, Bettendorf, - - 2014
The purpose of this study was to describe the rate of closure observed in venous leg ulcers during treatment with ovine collagen extracellular matrix dressings and compression. Fourteen patients with 23 wounds were retrospectively evaluated with respect to healing rates, time to closure, and weekly facility charge fees.
Cho Kyu-Sup KS Department of Otorhinolaryngology and Biomedical Research Institute, Pusan National University School of Medicine, Pusan National University Hospital, Yangsan, South - - 2014
Commercial gelatin-based packing materials are available under different names and compositions to be used after endoscopic sinus surgery (ESS). The purpose of this study was to investigate the efficacy of Spongostan and Cutanplast nasal packing on patients' subjective symptoms, hemostasis, and wound healing following ESS. One hundred adult patients with ...
Yamamichi Fukashi F Division of Urology, Department of Organ Therapeutics, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe, - - 2014
The number of open radical prostatectomy (RP) surgeries has been decreasing owing to the spread of laparoscopic and robotic surgery, which has implications for postoperative wound healing. The purpose of this study was to investigate and document the current status of postoperative wound healing and superficial surgical site infection (SSI) ...
Cheng Hsu-Tang HT Department of Surgery, China Medical University Hospital, Taichung, Taiwan School of Medicine, China Medical University, Taichung, Taiwan - - 2014
A best evidence topic in vascular surgery was written according to a structured protocol. The question addressed was whether it is safe and effective to use negative pressure wound therapy (NPWT) for Szilagyi grade III (i.e. the arterial implant proper involved in the infection) peripheral vascular graft infection. Altogether, 69 ...
Kenig Jakub - - 2014
The medical literature includes two risk scores predicting the occurrence of abdominal wound dehiscence. These risk indices were validated by the authors on the populations studied. However, whether these scoring systems can accurately predict, abdominal wound dehiscence in other populations remains unclear. A retrospective analysis was performed using the medical ...
Maan Zeshaan N ZN Stanford, Calif. From the Department of Surgery, Stanford University School of - - 2014
Chronic wounds are a major source of morbidity for patients and represent a significant health burden. Implementing noninvasive techniques that accelerate healing of these wounds would provide great benefit. Ultrasound appears to be an effective modality for the treatment of chronic wounds in humans. MIST Therapy is a noncontact, low-frequency ...
McDaniel Jodi C JC Jodi C. McDaniel, PhD, RN, Assistant Professor, College of Nursing, The Ohio State University, Columbus. Kristine K. Browning, PhD, Assistant professor, clinical nursing College of Nursing, The Ohio State University, - - 2014
Chronic wounds are rising in prevalence and creating significant socioeconomic burdens for patients and healthcare systems worldwide. Therefore, it is now more important than ever that clinicians follow evidence-based guidelines for wound care when developing personalized treatment plans for their patients with chronic wounds. Evidence-based guidelines for treating venous leg ...
Sanders Lee L Department of Podiatric Medicine, Temple University, School of Podiatric Medicine, Philadelphia, - - 2014
An estimated 25% of all people with diabetes may experience a foot ulcer in their lifetime, which may lead to serious complications including infection and amputation. A prospective, multicenter, randomized, controlled clinical trial was conducted to compare an in vitro-engineered, human fibroblast-derived dermal skin (HFDS) substitute and a biologically active ...
Blanco-Mezquita Tomas T *Department of Ophthalmology, Duke Eye Center, Duke University School of Medicine, Durham, NC; †Department of Ophthalmology, "Instituto Universitario de Oftalmobiología Aplicada" (IOBA), University of Valladolid, Valladolid, Spain; ‡Animal Facilities, University of Valladolid, Valladolid, Spain; §Department of Cell Biology and Pharmacology, University of Valladolid, Valladolid, Spain; and ¶Instituto Oftalmológico Fernández-Vega, Fundación de Investigación en Oftalmología, University of Oviedo, Oviedo, - - 2014
In this study, we investigated the wound-healing process after photorefractive keratectomy with mitomycin C (MMC) in hen corneas. In addition, we evaluated the synergistic effect of ethanol and MMC. Forty-eight adult hens were divided into 3 groups: A: ethanol-assisted debridement plus MMC; B: mechanical debridement plus MMC; and C: mechanical ...
Wu Zhengzheng Z Jinan University, Institute of Biomedicine, Guangzhou, Guangdong, China ; - - 2014
Skin damage is one of common clinical skin diseases, and the main cure is the use of skin graft, especially for large area of skin injury or deep skin damage. However, skin graft demand is far greater than that currently available. In this study, xenogeneic decellularized scaffold was prepared with ...
Son Bong Soo BS Department of Thoracic and Cardiovascular Surgery, Pusan National University Yangsan Hospital, Yangsan, South - - 2014
A 2-3-cm blowhole incision in the supraclavicular or infraclavicular area is widely used to eliminate the presence of subcutaneous air in cases of life-threatening subcutaneous emphysema (SE). However, when the patient is supported by mechanical ventilation, it is difficult to eliminate completely such air because mechanical ventilation leads consistently to ...
Nguyen Trang Q TQ From the *Department of Surgery, Section of Plastic and Reconstructive Surgery, University of Chicago Medicine, Illinois; †Department of Therapy Services, University of Chicago Medicine, Illinois; and ‡Division of Plastic and Reconstructive Surgery, UCLA David Geffen School of Medicine, Los Angeles, - - 2014
Negative pressure wound therapy (NPWT) has revolutionized the management of complicated wounds and has contributed an additional modality for securing split thickness skin grafts (STSG). The standard for NPWT is the vacuum-assisted closure (VAC) device. The authors' institution has accumulated experience using standard gauze sealed with an occlusive dressing and ...
Genuino Glenn Angelo S GA Division of Plastic Surgery, Department of Surgery, Philippine General Hospital, University of the Philippines, Manila, Philippines. Electronic address: - - 2014
Non-extensive superficial partial thickness burns constitute a major proportion of burns. Conventional treatment involves regular changing of absorptive dressings including the application of a topical antimicrobial, commonly silver sulfadiazine. A systematic review has found insufficient evidence to support or refute such antimicrobial prophylaxis. Another review compared silver sulfadiazine dressings with ...
de Mattos Luiz Henrique Lima LH Department of Surgery and Anaesthesiology of Large Animals, Faculty of Veterinary Medicine and Animal Science, UNESP - Univ Estadual Paulista, Distritic of Rubião Junior, s/n, 18618-970, Botucatu, São Paulo, - - 2014
The effect of phototherapy with 890-nm light-emitting diodes (LEDs) on the healing of experimentally induced tendinitis in sheep was evaluated in this study. Partial tenotomies measuring 0.2 cm wide × 0.5 cm long were performed on the second third of the superficial digital flexor tendons of 10 healthy sheep. The animals were divided into ...
Wang Siqun - - 2014
ObjectiveThis study investigated the effect of the knee position during wound closure on early knee function recovery after total knee arthroplasty (TKA).MethodsThis study included 80 primary total knee arthroplasties due to osteoarthritis. The patients were randomized according to the type of wound closure: extension group for full extension and flexion ...
Zeng Ying - - 2014
Abstract Background Imiquimod 5% cream is widely regarded as a safe and effective option when treating recalcitrant warts, owing to the ointments negligible side effects. However, our observations highlighted case of patient incurring severe adverse reactions to the cream's application, although the treatment proved successful in curing recalcitrant warts which ...
Kapila S S Department of Dermatology, Kolling Institute of Medical Research, University of Sydney Royal North Shore Hospital, St Leonards, NSW, - - 2014
Pyoderma gangrenosum (PG) is a systemic disease that presents with cutaneous necrotizing ulceration, producing deep necrotic ulcers, usually with a raised, undermined, violaceous border. Treatment typically involves high dose immunosuppressive drugs, but more recently anti-tumour necrosis factor and monoclonal antibodies have been used. Activated protein C (APC) stimulates wound healing ...
Mak Suzanne So-Shan SS Department of Clinical Oncology, Prince of Wales Hospital, Hong Kong. Electronic address: - - 2014
Wound cleansing should create an optimal healing environment by removing excess debris, exudates, foreign and necrotic material which are commonly present in the wounds that heal by secondary intention. At present, there is no research evidence for whether pressurised irrigation has better wound healing outcomes compared with conventional swabbing practice ...
Jordan Martin C - - 2014
BackgroundBarbed suture material offers the possibility of knotless flexor tendon repair, as suggested in an increasing number of biomechanical studies. There are currently two different absorbable barbed suture products available, V-Loc¿ and Stratafix¿, and both have not been compared to each other with regard to flexor tendon repair. The purpose ...
Fox Alice J S AJ Laboratory for Soft Tissue Research, Hospital for Special Surgery, New York, New York, USA foxa@hss.edu - - 2014
Recent studies suggest that fluoroquinolone antibiotics predispose tendons to tendinopathy and/or rupture. However, no investigations on the reparative capacity of tendons exposed to fluoroquinolones have been conducted. Fluoroquinolone-treated animals will have inferior biochemical, histological, and biomechanical properties at the healing tendon-bone enthesis compared with controls. Controlled laboratory study. Ninety-two rats ...
Nitzschke Stephanie L SL From the *U.S. Army Institute of Surgical Research, Fort Sam Houston, Texas;†Uniformed Services University for the Health Sciences, Bethesda, Maryland; ‡Naval Medical Research Unit-San Antonio, Fort Sam Houston, Texas; §University of Texas Health Science Center at San - - 2014
The rate of wound healing and its effect on mortality has not been well described. The objective of this article is to report wound healing trajectories in burn patients and analyze their effects on in-hospital mortality. The authors used software (WoundFlow) to depict burn wounds, surgical results, and healing progression ...
Bene M Del MD S. Gerardo Hospital, Department of Plastic, Hand Surgery and Reconstructive Microsurgery, Monza, - - 2014
Background: Digital ulcers (DUs) occur in up to 50% of patients with Systemic Sclerosis (SSc). DUs are painful, recurring and lead to functional disability. Management of DUs includes pharmacologic and local therapy, the healing process is slow and the ulcer can become infected or evolve to gangrene. Autologous fat grafting ...
Yu Myeong Sang MS Department of Otolaryngology, Konkuk University School of Medicine, Chungju, - - 2014
The purpose of this study was to investigate the effect of aerosolized fibrin sealant (FS) compared with that of polyvinyl acetal sponge packing on hemostasis and wound healing after functional endoscopic sinus surgery (FESS). We conducted a prospective randomized controlled trial of the use of aerosolized FS in 41 consecutive ...
Baillargeon Emilie E Division of Urology, McGill University, Montreal, - - 2014
We sought to determine whether the use of preoperative antibiotics is effective in reducing postoperative wound infections and urinary tract infections (UTI) in hypospadias repair. We retrospectively reviewed all hypospadias repairs performed at the Montreal Children's Hospital between March 2009 and September 2012. All types of primary hypospadias repairs and ...
Mohajeri Gholamreza G Department of Thoracic Surgery, Isfahan University of Medical Sciences, Isfahan, - - 2014
Kiwifruit (Actindia Deliciosa) is demonstrated to have antibacterial and pro-angiogenic effects. It also contains proteolytic enzymes (actinidin) and ascorbic acid. In this study, the effects of Kiwifruit on neuropathic diabetic foot ulcer healing in clinical settings were evaluated. In this randomized clinical trial of 37 patients (17 in experimental and ...
You Tae-Min TM Assistant Professor, Department of Advanced General Dentistry, Dental Hospital, Dankook University, Cheonan, South - - 2014
To evaluate the change in mandibular second-molar (M2) angulation in orthodontic treatment with premolar extraction and lower third molar (M3). Panoramic radiographs were evaluated in 3 groups of 129 participants: (1) control, no orthodontic treatment (n = 65); (2) extraction, orthodontic treatment with premolar extraction (n = 30); and (3) nonextraction, orthodontic ...
Honnegowda Thittamaranahalli Muguregowda TM Department of Plastic Surgery and Burns, Kasturba Medical College, Manipal, Karnataka, - - 2014
Healing ability of nonhealing chronic ulcers can be assessed by estimating hydroxyproline, total protein and enzymatic antioxidants such as glutathione peroxidase (GPx), glutathione S-transferase (GST) in the granulation tissue. A total of 34 patients were analysed from two groups: Limited access dressing (LAD) group (n = 17) and conventional dressing ...
Papa G - - 2014
Aim. Purpose of this retrospective comparative study is to evaluate the results of reconstruction of diabetic feet by split thickness skin graft (STSG) and by dermal substitute Integra® covered by STSG in terms of vascularity of the reconstructed wound-bed by measurements of tissue oxygenation (TcPO2). Patients and Methods. 23 patients ...
Alsalleeh Fahd F Department of Surgical Specialties, College of Dentistry, University of Nebraska Medical Center, Lincoln, Nebraska; Department of Restorative Dental Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia. Electronic address: - - 2014
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a well-known complication caused by amino-bisphosphonate therapy. We document one case of BRONJ associated with oral administration of methotrexate, a known immunosuppressive drug used to treat rheumatoid arthritis. A 66-year-old woman was referred for evaluation and endodontic surgery of recently re-treated tooth 13. ...
MacFarlane Robert J RJ Department of Trauma and Orthopaedics, Macclesfield District General Hospital, East Cheshire NHS Trust, Victoria Road, Macclesfield SK10 3BL, - - 2014
Introduction. Debate exists amongst surgeons regarding the ideal suture material for skin closure in carpal tunnel decompression (CTD). This study compares wound related complications, patient satisfaction, and functional outcome following open carpal tunnel decompression in patients undergoing wound closure with either of two common absorbable and nonabsorbable suture types. Materials ...
Khater Mohammad M MM Ophthalmology Department, Tanta University Hospital, Tanta, El Gharbia Governorate, - - 2014
The purpose of this study was to evaluate the effect of use of contact lenses to improve visual outcome after repair of traumatic corneal wounds. Two groups of patients (n=30 each) with traumatic full thickness corneal wounds were entered into this study. All cases were caused by sharp objects such ...
D'Aquino S - - 2013
Preharvest infections or conidia load on fruit surface by Penicillium digitatum, P. italicum, Alternaria citri and other filamentous fungi can cause important postharvest losses of citrus fruit. Reduction in pruning frequency occurred in the last decade together with un-picked yield that eventually rots on the trees have increased the risk ...
Asplund D - - 2012
Extralevator abdominoperineal excision (APE) for low rectal tumours has been introduced to achieve improved local radicality. Fewer positive margins and intraoperative perforations have been reported compared with standard APE. The aim of this retrospective study was to compare short-term complications and results of the two techniques in our institution. Consecutive ...
Dhanani Jayesh J Department of Intensive Care Medicine, Prince Charles Hospital, Brisbane, Queensland, Australia. - - 2013
The study objective was to investigate the effect of renal failure on intermediate-term survival in cardiac surgery patients. All patients aged 18 years or older undergoing coronary artery bypass grafting, valvular surgery, thoracic aortic surgery, or a combination of these from January 1, 2002 to December 1, 2005 were included. ...
Buethe David D - - 2012
PURPOSE: We evaluated the ability of renal tumor complexity, as assessed by the R.E.N.A.L. (radius, exophytic, nearness to collecting system, anterior/posterior and location) nephrometry scoring system, to predict the functional efficacy of nephron sparing surgery. MATERIALS AND METHODS: We evaluated 42 patients who presented with an anatomically (32) or a ...
Chou Yu-Hsiang - - 2012
Relatively little is known about the long-term outcomes of different histologic types of primary glomerulonephritis in Asian populations. From 1993 to 2006, 987 patients undergoing renal biopsy were studied, and 580 patients (mean age=44.4 years, male=58.5%) with the four most common forms of glomerulonephritis (membranous nephropathy, focal and segmental glomerulosclerosis, ...
Gulati Sonia S College of nursing, AIIMS, New Delhi, 110029 - - 2014
To compare the healing of chronic wounds with honey dressing vs. Povidone iodine dressing in adult subjects with chronic wounds of ≥6 weeks of duration, attending wound care clinic in Surgical Out Patient Department of All India Institute of Medical Sciences, Surgical Out Patient Department of Jai Prakash Narayan Apex Trauma ...
Wada Yukihiro Y Nephrology Department of Internal Medicine, Showa University Northern Yokohama Hospital, Chigasaki-chuo 35-1, Tsuzuki, Yokohama 224-8503, Japan. - - 2013
Immunoglobulin (Ig) A nephropathy (IgAN) is characterized by mesangial deposits of IgA1 and C3, often with co-deposits of IgG. We attempted to clarify the clinical significance of mesangial IgG deposition in patients with IgAN. We retrospectively reviewed 57 patients who were diagnosed with IgAN on the basis of pathological examination ...
Tiryaki Sibel - - 2012
OBJECTIVE: To evaluate the clinical course of multicystic dysplastic kidney (MCDK) and to reveal any criteria indicating spontaneous involution. MATERIAL METHODS: Hospital records of patients with MCDK followed in two different institutions in 1994-2009 were reviewed and data were analyzed regarding involution. RESULTS: Records of 96 patients were reviewed, of ...
Jiang Wen-Ling - - 2012
Objective: To explore the association of urinary podocyte excretion and renal expression of podocyte-specific marker podocalyxin (PCX) with clinicopathological changes in immunoglobulin A nephropathy (IgAN). Methods: Morning urine samples from IgAN patients and healthy controls were collected. The expression of glomerular PCX was quantified in 50 IgAN patients diagnosed by ...
Kawamura Tetsuya - - 2012
Background: A multicenter case-control study on IgA nephropathy (IgAN) was conducted to develop an evidence-based clinicopathologic classification of IgAN for predicting long-term renal outcome. Methods: Two hundred and eighty-seven patients including those with isolated hematuria or very mild proteinuria were enrolled. During a median follow-up of 9.3 years after biopsy, ...
Tsuboi Kazuya K Department of Hematology, Nagoya Central Hospital, Nagoya, Japan. - - 2012
Fabry disease is a rare, X-linked, inherited lysosomal storage disorder that can be treated with the enzymes agalsidase alfa (Replagal) and agalsidase beta (Fabrazyme). Currently, there is a global shortage of agalsidase beta, and this has increased global demand for agalsidase alfa. We assess the feasibility of switching patients on ...
Maeda Isseki - - 2012
BACKGROUND: Indication of tonsillectomy in IgA nephropathy is controversial. The purpose of this study was to examine the efficacy of tonsillectomy on remission and progression of IgA nephropathy.METHODS: We conducted a single-center 7-year historical cohort study in 200 patients with biopsy-proven IgA nephropathy. Study outcomes were clinical remission defined as ...
Abbas Ahmed - - 2012
BackgroundPrevious studies have demonstrated that fibrates have an effect on creatinine concentrations. The pattern of change with fibrates in estimated glomerular filtration rate (eGFR), widely used in clinical practice, has not been previously described.MethodsData was retrospectively collected from 132 consecutive case notes of patients started on fibrates in a lipid ...
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