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Hall Barry J BJ aDepartment of Gastroenterology, Adelaide and Meath Hospital bDepartment of Gastroenterology, St James's Hospital, Dublin, - - 2014
Mucosal healing is increasingly recognized as an important treatment goal in Crohn's disease (CD). Data from colonic disease shows improved long-term outcomes in patients achieving complete mucosal healing. Little is currently known of this with respect to ileitis, which is increasingly diagnosed using small bowel capsule endoscopy. The study aimed ...
Su Zhongchun Z Institute of Biomedicine, National Engineering Research Center of Genetic Medicine, Key Lab for Genetic Medicine of Guangdong Province, Jinan University, Guangzhou 510632, - - 2014
Current therapy for skin wound healing still relies on skin transplantation. Many studies were done to try to find out ways to replace skin transplantation, but there is still no effective alternative therapy. In this study, decellularized scaffolds were prepared from pig peritoneum by a series of physical and chemical ...
Hensler Daniel D Department of Orthopaedic Surgery, University of Pittsburgh, 3471 Fifth Avenue, Pittsburgh, PA, 15213, - - 2014
Graft healing following anterior cruciate ligament (ACL) reconstruction is a complex process characterized by phases of healing that lead to ACL remodelling. Our hypothesis is that fibrin clot addition to ACL reconstruction will result in advanced graft remodelling and healing when compared to a control group at 12 weeks as observed ...
Notodihardjo Priscilla Valentin PV Department of Plastic and Reconstructive Surgery, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka, 573-1010, Japan, - - 2014
Platelet-rich plasma (PRP) contains numerous growth factors to promote wound healing and angiogenesis. The objective of this study was to explore the efficacy of biodegradable gelatin hydrogel impregnated with PRP releasate (PRPr) in the wound healing process compared with the single application of PRPr prepared from mouse PRP centrifuged by ...
Wang Chen - - 2014
PurposeTotal knee arthroplasty (TKA) is a popular procedure in severe osteoarthritis. But perioperative bleeding remains a problem. Floseal® is a mixture of thrombin and bovine gelatin which can benefit a lot on reducing intraoperative and postoperative bleeding. However, there is no enough evidence judging its safety and efficiency. So a ...
Siqueira Cláudia Patrícia Cardoso Martins CP Health Sciences Center, Universidade Estadual de Londrina, Londrina, Paraná, Brazil, - - 2014
The aim of this study was to evaluate the effects of LED therapy associated with compression therapy on chronic venous leg ulcers (CVUs). The study included CVU patients (n = 17, eight men) who were eligible for Unna's boot treatment. Ulcers were treated on a weekly basis with either LED therapy (625 nm, ...
Mommsen Philipp P Trauma Department, Hannover Medical School (MHH), Hannover, - - 2014
Low-molecular-weight heparins (LMWH), e.g. enoxaparin, represent the standard thromboprophylactic agents in Europe after total hip replacement. The oral direct thrombin inhibitor dabigatran etexilate provides comparable effectiveness and safety. The present study aimed to evaluate the influence of dabigatran etexilate on perioperative blood loss and wound secretion in total hip arthroplasty ...
Chaudhary Bikash B From the *Oncology Department of Oral and Maxillofacial Surgery, the First Affiliated Hospital of Xinjiang Medical University; and †Oncology Department of Oral & Maxillofacial Surgery, the First Affiliated Hospital of Xinjiang Medical University, Stomatology School of Xinjiang Medical University, Urumqi, Xinjiang, P. R. - - 2014
: The aim of the study was to evaluate the efficacy of the buccal fat pad (BFP) in the reconstruction of various intraoral maxillary defects as well as the success, anatomy, healing process, merits, demerits, and complications of this technique. The study was conducted in the Oral and Maxillofacial Surgery ...
Yanazume Shintaro S Department of Obstetrics and Gynecology, Faculty of Medicine, Kagoshima University, Kagoshima, - - 2014
The purpose of this study was to compare prophylactic subcutaneous drainage plus subcuticular sutures versus staples for the risk of wound separation after skin closure following gynecologic malignancy surgery, and to investigate the risk factors of this procedure. Patients were divided into two groups: 120 patients who were treated with ...
Tzaneva Stanislava S *Department of Dermatology, Division of General Dermatology, Medical University Vienna, Vienna, Austria; †Private Practice in Dermatology and Angiology, Vienna, - - 2014
Superficial reflux ablation and revascularization improve the long-term prognosis of venous and arterial leg ulcers but do not solve the problem of protracted healing of large chronic wounds. Skin grafting has been shown to successfully heal chronic leg ulcers. To identify risk factors for ulcer healing and recurrence after shave ...
Kluczynski Melissa A MA Department of Orthopaedics, School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, New - - 2014
Postoperative rehabilitation has been shown to affect healing of the rotator cuff after surgical repair. However, it is unknown whether an early or delayed rehabilitation protocol is most beneficial for healing. To determine whether early versus delayed passive range of motion (PROM) affects rotator cuff (RC) retear rates after surgery. ...
Davies Ce C Gloucestershire Leg Ulcer Service, Cheltenham General Hospital, UK - - 2014
Slough in chronic venous leg ulcers may be associated with delayed healing. The purpose of this study was to assess larval debridement in chronic venous leg ulcers and to assess subsequent effect on healing. All patients with chronic leg ulcers presenting to the leg ulcer service were evaluated for the ...
Najmi Mahtab M International Branch, Shahid Beheshti University of Medical Sciences, Tehran, - - 2014
The purpose of this study was to evaluate the effect of consumption of oral olive oil on clinical outcomes and wound healing of thermally injured patients with hospital stays. One hundred patients (mean age; 33.34±7 years) with 10-20% total body surface area, deep second degree and more burn wounds were ...
Webster Joan J Centre for Clinical Nursing, Royal Brisbane and Women's Hospital, Level 2, Building 34, Butterfield Street, Brisbane, Queensland, Australia, - - 2014
Indications for the use of negative pressure wound therapy (NPWT) are broadening with a range of systems now available on the market, including those designed for use on clean, closed incisions and skin grafts. Reviews have concluded that the evidence for the effectiveness of NPWT remains uncertain, however, it is ...
Choi S Y SY Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South - - 2014
Collagens have long been used in pharmaceuticals and food supplements for the improvement of skin. We evaluated the efficacy of high advanced-collagen tripeptide (HACP) on wound healing and skin recovery. Using an in vitro model, we performed HaCaT cell migration assays and collagen gel contraction assays using HACP concentrations of ...
Doerler Martin M Martin Doerler, MD, is a Dermatology Consultant at the Vein Center, Departments of Dermatology and Vascular Surgery, at Ruhr-University Bochum, Germany. Sabine Eming, MD, is a Professor in the Department of Dermatology at the University of Cologne, Germany. Joachim Dissemond, MD, is a Professor in the Department of Dermatology at the University of Essen, Germany. Anneke Wolter, MD, is a Resident in the Department of Dermatology at the University of Cologne, Germany. Maren Stoffels-Weindorf, MD, is a Resident in the Department of Dermatology at the University of Essen, Germany. Stefanie Reich-Schupke, MD, is the Department Head of the Competence Center for Phlebology and Dermatology, Artemed-Fachklinik Prof. Dr. Dr. Salfeld GmbH & Co. KG, Bad Oeynhausen, Germany. Peter Altmeyer, MD, is the Chief Physician and Professor of Dermatology in the Department of Dermatology, Venereology, and Allergology at Ruhr-University Bochum, Germany. Markus Stücker, MD, is a Professor at the Vein Center in the Departments of Dermatology and Vascular Surgery at Ruhr-University Bochum, - - 2014
To evaluate the efficacy, tolerability, and safety of a novel wound dressing containing epidermal growth factor (EGF) in a collagen-gel matrix on hard-to-heal venous leg ulcers. The authors included 33 hard-to-heal venous leg ulcers found on 31 patients. The EGF-containing dressing was applied 3 times while best practice conservative wound ...
Violette David B DB Jr David B. Violette Jr, MD, is Staff Surgeon, Lewis Gale Medical Center, Salem, Virginia. Dr Violette has disclosed that his institution has received past funding from Cook Biotech for the provision of writing assistance, medicines, equipment, or administrative - - 2014
Intramuscular and subcutaneous injections of foreign bodies have been used for a number of years for a variety of reasons, including medical and cosmetic purposes. The author describes a case of chronic wound complications secondary to intramuscular gold injections for the treatment of rheumatoid arthritis. The lesions were completely excised, ...
Durante C M CM Servizio di Vulnologia, Policlinico Militare "Celio", Roma, Italia - - - 2014
The objective of this multicenter observational clinical study was to evaluate the therapeutic effects of a polyhexanide and propyl betaine-based gel in the treatment of patients of every age, affected by chronic skin wounds. One hundred twenty-four patients (60% females, from 4-day-old to 91-year-old, mean age 59) were treated with ...
Cull David L DL Department of Surgery, University of South Carolina School of Medicine-Greenville, Greenville Health System/University Medical Center, Greenville, SC. Electronic address: - - 2014
The Society for Vascular Surgery (SVS) recently established the Lower Extremity Threatened Limb Classification System, a staging system using Wound characteristic, Ischemia, and foot Infection (WIfI) to stratify the risk for limb amputation at 1 year. Although intuitive in nature, this new system has not been validated. The purpose of the ...
Utsunomiya Makoto M 1 Division of Cardiovascular Medicine, Tokyo Rosai Hospital, Tokyo, - - 2014
Purpose : To determine the predictive value of skin perfusion pressure (SPP) for wound healing after endovascular therapy (EVT). Methods : Between May 2004 and March 2011, 113 consecutive patients (84 men; mean age 71.5±12.5 years) with CLI (123 limbs) underwent successful balloon angioplasty ± stenting (flow from >1 vessel ...
Iida Osamu O 1 Cardiovascular Center, Kansai Rosai Hospital, Amagasaki, - - 2014
Purpose : To investigate the impact of angiosome-oriented revascularization on clinical outcomes in critical limb ischemia (CLI) patients excluding those with both diabetes and wound infection. Methods : Using a retrospective multicenter database, a propensity score matching analysis was performed of 539 consecutive CLI patients (375 men; mean age 71±11 ...
Moran M E ME Assistant Professor; Department of Occupational Therapy Kean University 1000 Morris Avenue Union, New Jersey - - 2014
Digital ulcers are difficult to heal, increasing the chance of infection, gangrene, amputation and limited functional use of hands. They are a complication in scleroderma or systematic sclerosis (SSc) and occur in approximately 50% of patients. This is a systematic review of the evidence supporting the use of non-pharmaceutical therapeutic ...
Tejwani Nirmal C NC Department of Orthopaedics, New York University Hospital for Joint Diseases, New York, NY. - - 2014
We retrospectively compared the outcomes of early functional weight-bearing after use of 2 different approaches (minimally invasive, standard) for surgical repair of the Achilles tendon. We reviewed the cases of 63 consecutive patients who underwent repair of an acute closed Achilles tendon rupture and had follow-up of at least 6 ...
Batinjan Goran G Department of Oral Surgery, School of Dental Medicine, University of Zagreb, Zagreb, Croatia. E-mail. - - 2014
Radiation therapy of the head and neck area has resulted in numerous and undesired effects on the oral cavity tissue. The most frequent and most dangerous complications of radiotherapy of the head and neck area is osteoradionecrosis (ORN). The purpose of this study is to demonstrate the possibility of using ...
Nasr P P Addenbrookes University Hospital NHS Trust, Cambridge, - - 2014
Several studies have claimed ultrasound to be useful and accurate in assessing the healing phase of Achilles tendons after tenotomy during Ponseti treatment for clubfoot deformity. The purpose of our study was to assess the healing process of Achilles tendons ultrasonographically after tenotomy as part of Ponseti clubfoot management and ...
Batinjan G G Department of Oral Surgery, School of Dental Medicine and Clinical Hospital Centre Zagreb, University of Zagreb, Zagreb, Croatia. Electronic address: - - 2014
The objective of this study was to assess the impact of low-level laser therapy on wound swelling, wound temperature changes, and oral health-related quality of life (OHRQoL) after surgical removal of impacted lower third molars. Forty patients with impacted lower third molars requiring surgical removal participated in this study; all ...
Kim Jongseo A - - 2014
Abstract A novel dermal filler based on polycaprolactone (PCL) has been introduced to the aesthetic market. A recently published study has shown that the PCL-based dermal filler induces neocollagenesis in rabbit tissue, a process associated with improvement in the skin's appearance. In this pilot study we investigated if the PCL-based ...
Lim Hyun-Chang - - 2014
Purpose: This study compared the volume stability and bone-forming capacity of biphasic calcium phosphate (BCP) with a high versus a low ratio of β-tricalcium phosphate (β-TCP) relative to hydroxyapatite (HA), ie, 70:30 vs 30:70, in the rabbit sinus model. Materials and Methods: Bilateral sinus windows were created in eight adult ...
Kanematsu Yoshiji Y Department of Orthopaedic Surgery, Tokushima National Hospital, Tokushima, - - 2014
Little Leaguer's shoulder is a syndrome involving the proximal humeral epiphyseal plate. Conservative treatment usually resolves the symptoms. However, there are no reports of a radiographic follow-up study of this disease. The purpose of this study was to show the radiographic healing process of Little Leaguer's shoulder. A total of ...
Wilkie Mark D MD Department of Otorhinolaryngology-Head and Neck Surgery, Countess of Chester Hospital, Chester, United Kingdom - - 2014
Recently, a novel hydroxyapatite-coated concave bone-anchored hearing device abutment was introduced, the first designed specifically to improve outcomes in soft-tissue preservation osseointegrated hearing implant surgery. We sought to evaluate our early experience with this abutment. A single-center case series with planned data collection including patient-reported outcomes. Tertiary referral center. The ...
Hall Barry B Department of Gastroenterology, Adelaide and Meath Hospital, Dublin 24, Ireland. Electronic address: - - 2014
Mucosal healing is increasingly recognised as an important treatment goal in Crohn's disease (CD). Data from colonic disease shows improved long-term outcomes in patients achieving complete mucosal healing. Little is currently known of this with regard to ileitis which is increasingly diagnosed using capsule endoscopy (SBCE). This is the first ...
van den Belt Lotte L Department of Orthopedics, Sint Maartenskliniek, Hengstdal 3, 6574 NA, Nijmegen, The Netherlands, - - 2014
To reduce post-operative length of hospital stay (PLOS) after primary total knee arthroplasty (TKA), the fast-track method was introduced which focusses on mobilising the patient within 2 h after surgery. The aim of this prospective study was to identify the factors that predict PLOS using the fast-track method. In a consecutive ...
Sahin Cihan C Gulhane Military Medical Academy, Haydarpasa Training Hospital, Department of Plastic, Reconstructive and Aesthetic Surgery and Burn Unit, Istanbul, Turkey. Electronic address: - - 2014
The aim of this paper was to report a rare cause of radionecrosis and its long-term results. Iridium-192 ((192)Ir) is commonly used for radiography as a gamma ray source to locate flaws in welds and metal components in gas and oil industry. A 38-year-old man was subjected to radiation unintentionally. ...
Motififard Mahdi M Orthopaedic Department, Kashani Hospital, Isfahan University of Medical Sciences, Isfahan, - - 2014
Total knee arthroplasty (TKA) is one of the most common surgeries performed in orthopedics. The null hypothesis of the present study was that wound closure in extension or flexion does not have any impact on range of motion (ROM) and clinical outcome after TKA. This study was a double-blind prospective ...
Bollero Daniele D Department of General and Specialistic Surgery, Division of Plastic and Reconstructive Surgery, Burn Center, AOU Città della Salute, CTO Hospital, Turin, - - 2014
Negative pressure wound therapy (NPWT) is a treatment to reduce oedema, stimulate granulation tissue formation, remove wound exudate and diminish wound area, thus preparing it for secondary healing, skin grafting or coverage with flaps. The association of instillation to NPWT (NPWTi) is a new method for treating severe wounds, in ...
Ahn Ji-Hyun JH Department of Orthopedic Surgery, Dongguk University Ilsan Hospital, - - 2014
The purpose of this study was to evaluate patients after arthroscopic repair of meniscal horizontal tears with a marrow-stimulating technique through clinical signs and second-look arthroscopy. We retrospectively reviewed a consecutive series of 32 meniscal repairs with horizontal cleavage tears and evaluated them through clinical assessment and second-look arthroscopic examinations. ...
Nordentoft Tyge T Department of Gastrointestinal Surgery 360, Hvidovre Hospital, University of Copenhagen, Copenhagen, - - 2014
Background/Aim: Anastomotic leakage remains a frequent and serious complication in gastrointestinal surgery. In order to reduce its incidence, several clinical and experimental studies on anastomotic sealing have been performed. In a number of these studies, the sealing material has been fibrin glue (FG), and the results in individual studies have ...
De Caridi Giovanni G Cardiovascular and Thoracic Department, "Policlinico G. Martino" Hospital, University of Messina, Messina, - - 2014
The aim of this study is to report our experience about the treatment of complex sternal and thoracic wounds following cardiothoracic surgery, using vacuum-assisted closure (VAC therapy. Twelve patients presenting with sternal (five cases) and thoracic (seven cases) wounds that were difficult to heal were treated through VAC therapy after ...
De Caridi Giovanni G Cardiovascular and Thoracic Department,"Policlinico G. Martino" Hospital, University of Messina, Messina, - - 2014
The aim of this study was to evaluate the results of treatment of venous lower limbs ulcers through the topical application of polynucleotides and hyaluronic acid gel (PNHA): Nucliaskin S™ (Mastelli srl, San Remo, Italy). This study was carried out in 39 consecutive patients who were randomly allocated to two ...
Serena Thomas E TE Clinical Research, SerenaGroup Wound and Hyperbaric Centers, Warren, - - 2014
Venous leg ulcers produce significant clinical and economic burdens on society and often require advanced wound therapy. The purpose of this multi-center, randomized, controlled study is to evaluate the safety and efficacy of 1 or 2 applications of dehydrated human amnion/chorion membrane allograft and multi-layer compression therapy versus multi-layer compression ...
Taggart David P DP Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Oxford, UK - - 2014
The Arterial Revascularization Trial (ART) is a randomized comparison of bilateral internal mammary artery (BIMA) versus single internal mammary artery (SIMA) grafting in coronary artery bypass graft (CABG) surgery and is one of the largest randomized trials of surgery ever conducted. ART is also one of the largest studies of ...
Talha Ahmed A Department of Surgery, Medical Research Institute, Alexandria University, Alexandria, - - 2014
This study was designed to compare the surgical outcomes of haemorrhoidectomy performed by the Ligasure, Harmonic Scalpel with that performed by the conventional diathermy. A total of 180 patients were randomized to Ligasure, Harmonic Scalpel and diathermy haemorrhoidectomy, 60 patients for each group. The operative time, post-operative pain scores, parenteral ...
- - 2014
This study was designed to evaluate the safety and efficacy of a novel, self? cross-linked hyaluronic acid (HA) hydrogel compared with carboxymethylcellulose (CMC) viscous foam in promoting healing when applied after ethmoidectomy. A prospective, randomized, controlled, blinded clinical trial was performed. The study was performed by four surgeons operating in ...
Nelson E Andrea EA School of Healthcare, University of Leeds, Baines Wing, Leeds, UK, LS2 - - 2014
Up to 1% of adults will have a leg ulcer at some time. The majority of leg ulcers are venous in origin and are caused by high pressure in the veins due to blockage or weakness of the valves in the veins of the leg. Prevention and treatment of venous ...
Zölß Christoph C Ambulatorien der Steiermärkischen Gebietskrankenkasse, Fachärztezentrum Graz, Graz, - - 2014
Chronic wounds represent a large and growing segment of health care and add considerably to human suffering and economic burden as populations age. More effective materials, especially those promoting ease of use and economy, are needed to treat this increasing number of patients. A case series conducted at a European ...
Boggio Ricardo Frota RF Department of Cell and Development Biology, Institute of Biomedical Science, University of São Paulo, Av. Prof. Lineu Prestes, 1524, ICB I rooms 306/307, Butantan, São Paulo, SP, 05508-900, Brazil, - - 2014
Skin injuries and the consequent loss of tissue integrity triggers a sequence of cellular and biochemical events that lead to a healed wound. Any failure during this rather sophisticated process may result in pathological scarring. To evaluate the efficacy of topical verapamil as a modulator of the healing process, a ...
Bohn Gregory A GA Gregory A. Bohn, MD, FACS, is Medical Director, The Center for Wound and Hyperbaric Medicine at West Shore Medical Center, Manistee, Michigan. Kimberly Gass, RN, is a Nurse, Trinity Wound Center for Wound and Hyperbaric Medicine, Bettendorf, - - 2014
The purpose of this study was to describe the rate of closure observed in venous leg ulcers during treatment with ovine collagen extracellular matrix dressings and compression. Fourteen patients with 23 wounds were retrospectively evaluated with respect to healing rates, time to closure, and weekly facility charge fees.
Cho Kyu-Sup KS Department of Otorhinolaryngology and Biomedical Research Institute, Pusan National University School of Medicine, Pusan National University Hospital, Yangsan, South - - 2014
Commercial gelatin-based packing materials are available under different names and compositions to be used after endoscopic sinus surgery (ESS). The purpose of this study was to investigate the efficacy of Spongostan and Cutanplast nasal packing on patients' subjective symptoms, hemostasis, and wound healing following ESS. One hundred adult patients with ...
Yamamichi Fukashi F Division of Urology, Department of Organ Therapeutics, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe, - - 2014
The number of open radical prostatectomy (RP) surgeries has been decreasing owing to the spread of laparoscopic and robotic surgery, which has implications for postoperative wound healing. The purpose of this study was to investigate and document the current status of postoperative wound healing and superficial surgical site infection (SSI) ...
Cheng Hsu-Tang HT Department of Surgery, China Medical University Hospital, Taichung, Taiwan School of Medicine, China Medical University, Taichung, Taiwan - - 2014
A best evidence topic in vascular surgery was written according to a structured protocol. The question addressed was whether it is safe and effective to use negative pressure wound therapy (NPWT) for Szilagyi grade III (i.e. the arterial implant proper involved in the infection) peripheral vascular graft infection. Altogether, 69 ...
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