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Hall Barry J BJ aDepartment of Gastroenterology, Adelaide and Meath Hospital bDepartment of Gastroenterology, St James's Hospital, Dublin, - - 2014
Mucosal healing is increasingly recognized as an important treatment goal in Crohn's disease (CD). Data from colonic disease shows improved long-term outcomes in patients achieving complete mucosal healing. Little is currently known of this with respect to ileitis, which is increasingly diagnosed using small bowel capsule endoscopy. The study aimed ...
Doerler Martin M Martin Doerler, MD, is a Dermatology Consultant at the Vein Center, Departments of Dermatology and Vascular Surgery, at Ruhr-University Bochum, Germany. Sabine Eming, MD, is a Professor in the Department of Dermatology at the University of Cologne, Germany. Joachim Dissemond, MD, is a Professor in the Department of Dermatology at the University of Essen, Germany. Anneke Wolter, MD, is a Resident in the Department of Dermatology at the University of Cologne, Germany. Maren Stoffels-Weindorf, MD, is a Resident in the Department of Dermatology at the University of Essen, Germany. Stefanie Reich-Schupke, MD, is the Department Head of the Competence Center for Phlebology and Dermatology, Artemed-Fachklinik Prof. Dr. Dr. Salfeld GmbH & Co. KG, Bad Oeynhausen, Germany. Peter Altmeyer, MD, is the Chief Physician and Professor of Dermatology in the Department of Dermatology, Venereology, and Allergology at Ruhr-University Bochum, Germany. Markus Stücker, MD, is a Professor at the Vein Center in the Departments of Dermatology and Vascular Surgery at Ruhr-University Bochum, - - 2014
To evaluate the efficacy, tolerability, and safety of a novel wound dressing containing epidermal growth factor (EGF) in a collagen-gel matrix on hard-to-heal venous leg ulcers. The authors included 33 hard-to-heal venous leg ulcers found on 31 patients. The EGF-containing dressing was applied 3 times while best practice conservative wound ...
Violette David B DB Jr David B. Violette Jr, MD, is Staff Surgeon, Lewis Gale Medical Center, Salem, Virginia. Dr Violette has disclosed that his institution has received past funding from Cook Biotech for the provision of writing assistance, medicines, equipment, or administrative - - 2014
Intramuscular and subcutaneous injections of foreign bodies have been used for a number of years for a variety of reasons, including medical and cosmetic purposes. The author describes a case of chronic wound complications secondary to intramuscular gold injections for the treatment of rheumatoid arthritis. The lesions were completely excised, ...
Kim Jongseo A - - 2014
Abstract A novel dermal filler based on polycaprolactone (PCL) has been introduced to the aesthetic market. A recently published study has shown that the PCL-based dermal filler induces neocollagenesis in rabbit tissue, a process associated with improvement in the skin's appearance. In this pilot study we investigated if the PCL-based ...
Lim Hyun-Chang - - 2014
Purpose: This study compared the volume stability and bone-forming capacity of biphasic calcium phosphate (BCP) with a high versus a low ratio of β-tricalcium phosphate (β-TCP) relative to hydroxyapatite (HA), ie, 70:30 vs 30:70, in the rabbit sinus model. Materials and Methods: Bilateral sinus windows were created in eight adult ...
Kanematsu Yoshiji Y Department of Orthopaedic Surgery, Tokushima National Hospital, Tokushima, - - 2014
Little Leaguer's shoulder is a syndrome involving the proximal humeral epiphyseal plate. Conservative treatment usually resolves the symptoms. However, there are no reports of a radiographic follow-up study of this disease. The purpose of this study was to show the radiographic healing process of Little Leaguer's shoulder. A total of ...
Wilkie Mark D MD Department of Otorhinolaryngology-Head and Neck Surgery, Countess of Chester Hospital, Chester, United Kingdom - - 2014
Recently, a novel hydroxyapatite-coated concave bone-anchored hearing device abutment was introduced, the first designed specifically to improve outcomes in soft-tissue preservation osseointegrated hearing implant surgery. We sought to evaluate our early experience with this abutment. A single-center case series with planned data collection including patient-reported outcomes. Tertiary referral center. The ...
Hall Barry B Department of Gastroenterology, Adelaide and Meath Hospital, Dublin 24, Ireland. Electronic address: - - 2014
Mucosal healing is increasingly recognised as an important treatment goal in Crohn's disease (CD). Data from colonic disease shows improved long-term outcomes in patients achieving complete mucosal healing. Little is currently known of this with regard to ileitis which is increasingly diagnosed using capsule endoscopy (SBCE). This is the first ...
van den Belt Lotte L Department of Orthopedics, Sint Maartenskliniek, Hengstdal 3, 6574 NA, Nijmegen, The Netherlands, - - 2014
To reduce post-operative length of hospital stay (PLOS) after primary total knee arthroplasty (TKA), the fast-track method was introduced which focusses on mobilising the patient within 2 h after surgery. The aim of this prospective study was to identify the factors that predict PLOS using the fast-track method. In a consecutive ...
Sahin Cihan C Gulhane Military Medical Academy, Haydarpasa Training Hospital, Department of Plastic, Reconstructive and Aesthetic Surgery and Burn Unit, Istanbul, Turkey. Electronic address: - - 2014
The aim of this paper was to report a rare cause of radionecrosis and its long-term results. Iridium-192 ((192)Ir) is commonly used for radiography as a gamma ray source to locate flaws in welds and metal components in gas and oil industry. A 38-year-old man was subjected to radiation unintentionally. ...
Motififard Mahdi M Orthopaedic Department, Kashani Hospital, Isfahan University of Medical Sciences, Isfahan, - - 2014
Total knee arthroplasty (TKA) is one of the most common surgeries performed in orthopedics. The null hypothesis of the present study was that wound closure in extension or flexion does not have any impact on range of motion (ROM) and clinical outcome after TKA. This study was a double-blind prospective ...
Bollero Daniele D Department of General and Specialistic Surgery, Division of Plastic and Reconstructive Surgery, Burn Center, AOU Città della Salute, CTO Hospital, Turin, - - 2014
Negative pressure wound therapy (NPWT) is a treatment to reduce oedema, stimulate granulation tissue formation, remove wound exudate and diminish wound area, thus preparing it for secondary healing, skin grafting or coverage with flaps. The association of instillation to NPWT (NPWTi) is a new method for treating severe wounds, in ...
Ahn Ji-Hyun JH Department of Orthopedic Surgery, Dongguk University Ilsan Hospital, - - 2014
The purpose of this study was to evaluate patients after arthroscopic repair of meniscal horizontal tears with a marrow-stimulating technique through clinical signs and second-look arthroscopy. We retrospectively reviewed a consecutive series of 32 meniscal repairs with horizontal cleavage tears and evaluated them through clinical assessment and second-look arthroscopic examinations. ...
Nordentoft Tyge T Department of Gastrointestinal Surgery 360, Hvidovre Hospital, University of Copenhagen, Copenhagen, - - 2014
Background/Aim: Anastomotic leakage remains a frequent and serious complication in gastrointestinal surgery. In order to reduce its incidence, several clinical and experimental studies on anastomotic sealing have been performed. In a number of these studies, the sealing material has been fibrin glue (FG), and the results in individual studies have ...
De Caridi Giovanni G Cardiovascular and Thoracic Department, "Policlinico G. Martino" Hospital, University of Messina, Messina, - - 2014
The aim of this study is to report our experience about the treatment of complex sternal and thoracic wounds following cardiothoracic surgery, using vacuum-assisted closure (VAC therapy. Twelve patients presenting with sternal (five cases) and thoracic (seven cases) wounds that were difficult to heal were treated through VAC therapy after ...
De Caridi Giovanni G Cardiovascular and Thoracic Department,"Policlinico G. Martino" Hospital, University of Messina, Messina, - - 2014
The aim of this study was to evaluate the results of treatment of venous lower limbs ulcers through the topical application of polynucleotides and hyaluronic acid gel (PNHA): Nucliaskin S™ (Mastelli srl, San Remo, Italy). This study was carried out in 39 consecutive patients who were randomly allocated to two ...
Serena Thomas E TE Clinical Research, SerenaGroup Wound and Hyperbaric Centers, Warren, - - 2014
Venous leg ulcers produce significant clinical and economic burdens on society and often require advanced wound therapy. The purpose of this multi-center, randomized, controlled study is to evaluate the safety and efficacy of 1 or 2 applications of dehydrated human amnion/chorion membrane allograft and multi-layer compression therapy versus multi-layer compression ...
Taggart David P DP Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Oxford, UK - - 2014
The Arterial Revascularization Trial (ART) is a randomized comparison of bilateral internal mammary artery (BIMA) versus single internal mammary artery (SIMA) grafting in coronary artery bypass graft (CABG) surgery and is one of the largest randomized trials of surgery ever conducted. ART is also one of the largest studies of ...
Talha Ahmed A Department of Surgery, Medical Research Institute, Alexandria University, Alexandria, - - 2014
This study was designed to compare the surgical outcomes of haemorrhoidectomy performed by the Ligasure, Harmonic Scalpel with that performed by the conventional diathermy. A total of 180 patients were randomized to Ligasure, Harmonic Scalpel and diathermy haemorrhoidectomy, 60 patients for each group. The operative time, post-operative pain scores, parenteral ...
- - 2014
This study was designed to evaluate the safety and efficacy of a novel, self? cross-linked hyaluronic acid (HA) hydrogel compared with carboxymethylcellulose (CMC) viscous foam in promoting healing when applied after ethmoidectomy. A prospective, randomized, controlled, blinded clinical trial was performed. The study was performed by four surgeons operating in ...
Nelson E Andrea EA School of Healthcare, University of Leeds, Baines Wing, Leeds, UK, LS2 - - 2014
Up to 1% of adults will have a leg ulcer at some time. The majority of leg ulcers are venous in origin and are caused by high pressure in the veins due to blockage or weakness of the valves in the veins of the leg. Prevention and treatment of venous ...
Zölß Christoph C Ambulatorien der Steiermärkischen Gebietskrankenkasse, Fachärztezentrum Graz, Graz, - - 2014
Chronic wounds represent a large and growing segment of health care and add considerably to human suffering and economic burden as populations age. More effective materials, especially those promoting ease of use and economy, are needed to treat this increasing number of patients. A case series conducted at a European ...
Boggio Ricardo Frota RF Department of Cell and Development Biology, Institute of Biomedical Science, University of São Paulo, Av. Prof. Lineu Prestes, 1524, ICB I rooms 306/307, Butantan, São Paulo, SP, 05508-900, Brazil, - - 2014
Skin injuries and the consequent loss of tissue integrity triggers a sequence of cellular and biochemical events that lead to a healed wound. Any failure during this rather sophisticated process may result in pathological scarring. To evaluate the efficacy of topical verapamil as a modulator of the healing process, a ...
Bohn Gregory A GA Gregory A. Bohn, MD, FACS, is Medical Director, The Center for Wound and Hyperbaric Medicine at West Shore Medical Center, Manistee, Michigan. Kimberly Gass, RN, is a Nurse, Trinity Wound Center for Wound and Hyperbaric Medicine, Bettendorf, - - 2014
The purpose of this study was to describe the rate of closure observed in venous leg ulcers during treatment with ovine collagen extracellular matrix dressings and compression. Fourteen patients with 23 wounds were retrospectively evaluated with respect to healing rates, time to closure, and weekly facility charge fees.
Cho Kyu-Sup KS Department of Otorhinolaryngology and Biomedical Research Institute, Pusan National University School of Medicine, Pusan National University Hospital, Yangsan, South - - 2014
Commercial gelatin-based packing materials are available under different names and compositions to be used after endoscopic sinus surgery (ESS). The purpose of this study was to investigate the efficacy of Spongostan and Cutanplast nasal packing on patients' subjective symptoms, hemostasis, and wound healing following ESS. One hundred adult patients with ...
Yamamichi Fukashi F Division of Urology, Department of Organ Therapeutics, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe, - - 2014
The number of open radical prostatectomy (RP) surgeries has been decreasing owing to the spread of laparoscopic and robotic surgery, which has implications for postoperative wound healing. The purpose of this study was to investigate and document the current status of postoperative wound healing and superficial surgical site infection (SSI) ...
Cheng Hsu-Tang HT Department of Surgery, China Medical University Hospital, Taichung, Taiwan School of Medicine, China Medical University, Taichung, Taiwan - - 2014
A best evidence topic in vascular surgery was written according to a structured protocol. The question addressed was whether it is safe and effective to use negative pressure wound therapy (NPWT) for Szilagyi grade III (i.e. the arterial implant proper involved in the infection) peripheral vascular graft infection. Altogether, 69 ...
Morgaz Juan J Department of Animal Medicine and Surgery, University of Córdoba, Francisco Santisteban Hospital, Campus de Rabanales 14014, Córdoba, Spain. Electronic address: - - 2014
This study compared the post-operative analgesic efficacy of continuous lidocaine administration with that of intramuscular (IM) methadone in dogs undergoing ovariohysterectomy. Thirty-eight dogs were divided randomly into two groups. Following surgery, the lidocaine group (L) received a continuous lidocaine infusion (2 mg/kg/h) through a wound catheter inserted in the pre-peritoneal space; ...
Kenig Jakub - - 2014
The medical literature includes two risk scores predicting the occurrence of abdominal wound dehiscence. These risk indices were validated by the authors on the populations studied. However, whether these scoring systems can accurately predict, abdominal wound dehiscence in other populations remains unclear. A retrospective analysis was performed using the medical ...
Yauw Simon T K ST Department of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address: - - 2014
Anastomotic leakage rates remain unacceptably high, warranting reconsideration of current anastomotic technique. Anastomotic healing may improve by abrading the serosal surface of bowel ends that are invertedly anastomosed, based on the concept that serosal damage evokes inflammatory adherent processes. It is studied if local abrasion leads to stronger anastomoses and ...
Maan Zeshaan N ZN Stanford, Calif. From the Department of Surgery, Stanford University School of - - 2014
Chronic wounds are a major source of morbidity for patients and represent a significant health burden. Implementing noninvasive techniques that accelerate healing of these wounds would provide great benefit. Ultrasound appears to be an effective modality for the treatment of chronic wounds in humans. MIST Therapy is a noncontact, low-frequency ...
McDaniel Jodi C JC Jodi C. McDaniel, PhD, RN, Assistant Professor, College of Nursing, The Ohio State University, Columbus. Kristine K. Browning, PhD, Assistant professor, clinical nursing College of Nursing, The Ohio State University, - - 2014
Chronic wounds are rising in prevalence and creating significant socioeconomic burdens for patients and healthcare systems worldwide. Therefore, it is now more important than ever that clinicians follow evidence-based guidelines for wound care when developing personalized treatment plans for their patients with chronic wounds. Evidence-based guidelines for treating venous leg ...
Sanders Lee L Department of Podiatric Medicine, Temple University, School of Podiatric Medicine, Philadelphia, - - 2014
An estimated 25% of all people with diabetes may experience a foot ulcer in their lifetime, which may lead to serious complications including infection and amputation. A prospective, multicenter, randomized, controlled clinical trial was conducted to compare an in vitro-engineered, human fibroblast-derived dermal skin (HFDS) substitute and a biologically active ...
Nogueira Veruska Cronemberger VC University of Vale do Paraiba, Sao Jose dos Campos, SP, - - 2014
To compare the biomodulatory effects of LED and ultrasound combined with semipermeable dressing in the repair of cutaneous lesions. Eighty-four Wistar rats were submitted to surgical injury (2.5 cm) and divided into four groups (n=21): Group I (control), Group II (LED therapy, LED), Group III (LED therapy + dressing, LED+D) ...
Blanco-Mezquita Tomas T *Department of Ophthalmology, Duke Eye Center, Duke University School of Medicine, Durham, NC; †Department of Ophthalmology, "Instituto Universitario de Oftalmobiología Aplicada" (IOBA), University of Valladolid, Valladolid, Spain; ‡Animal Facilities, University of Valladolid, Valladolid, Spain; §Department of Cell Biology and Pharmacology, University of Valladolid, Valladolid, Spain; and ¶Instituto Oftalmológico Fernández-Vega, Fundación de Investigación en Oftalmología, University of Oviedo, Oviedo, - - 2014
In this study, we investigated the wound-healing process after photorefractive keratectomy with mitomycin C (MMC) in hen corneas. In addition, we evaluated the synergistic effect of ethanol and MMC. Forty-eight adult hens were divided into 3 groups: A: ethanol-assisted debridement plus MMC; B: mechanical debridement plus MMC; and C: mechanical ...
Wu Zhengzheng Z Jinan University, Institute of Biomedicine, Guangzhou, Guangdong, China ; - - 2014
Skin damage is one of common clinical skin diseases, and the main cure is the use of skin graft, especially for large area of skin injury or deep skin damage. However, skin graft demand is far greater than that currently available. In this study, xenogeneic decellularized scaffold was prepared with ...
Son Bong Soo BS Department of Thoracic and Cardiovascular Surgery, Pusan National University Yangsan Hospital, Yangsan, South - - 2014
A 2-3-cm blowhole incision in the supraclavicular or infraclavicular area is widely used to eliminate the presence of subcutaneous air in cases of life-threatening subcutaneous emphysema (SE). However, when the patient is supported by mechanical ventilation, it is difficult to eliminate completely such air because mechanical ventilation leads consistently to ...
Nguyen Trang Q TQ From the *Department of Surgery, Section of Plastic and Reconstructive Surgery, University of Chicago Medicine, Illinois; †Department of Therapy Services, University of Chicago Medicine, Illinois; and ‡Division of Plastic and Reconstructive Surgery, UCLA David Geffen School of Medicine, Los Angeles, - - 2014
Negative pressure wound therapy (NPWT) has revolutionized the management of complicated wounds and has contributed an additional modality for securing split thickness skin grafts (STSG). The standard for NPWT is the vacuum-assisted closure (VAC) device. The authors' institution has accumulated experience using standard gauze sealed with an occlusive dressing and ...
Genuino Glenn Angelo S GA Division of Plastic Surgery, Department of Surgery, Philippine General Hospital, University of the Philippines, Manila, Philippines. Electronic address: - - 2014
Non-extensive superficial partial thickness burns constitute a major proportion of burns. Conventional treatment involves regular changing of absorptive dressings including the application of a topical antimicrobial, commonly silver sulfadiazine. A systematic review has found insufficient evidence to support or refute such antimicrobial prophylaxis. Another review compared silver sulfadiazine dressings with ...
de Mattos Luiz Henrique Lima LH Department of Surgery and Anaesthesiology of Large Animals, Faculty of Veterinary Medicine and Animal Science, UNESP - Univ Estadual Paulista, Distritic of Rubião Junior, s/n, 18618-970, Botucatu, São Paulo, - - 2014
The effect of phototherapy with 890-nm light-emitting diodes (LEDs) on the healing of experimentally induced tendinitis in sheep was evaluated in this study. Partial tenotomies measuring 0.2 cm wide × 0.5 cm long were performed on the second third of the superficial digital flexor tendons of 10 healthy sheep. The animals were divided into ...
Wang Siqun - - 2014
ObjectiveThis study investigated the effect of the knee position during wound closure on early knee function recovery after total knee arthroplasty (TKA).MethodsThis study included 80 primary total knee arthroplasties due to osteoarthritis. The patients were randomized according to the type of wound closure: extension group for full extension and flexion ...
Zeng Ying - - 2014
Abstract Background Imiquimod 5% cream is widely regarded as a safe and effective option when treating recalcitrant warts, owing to the ointments negligible side effects. However, our observations highlighted case of patient incurring severe adverse reactions to the cream's application, although the treatment proved successful in curing recalcitrant warts which ...
Kapila S S Department of Dermatology, Kolling Institute of Medical Research, University of Sydney Royal North Shore Hospital, St Leonards, NSW, - - 2014
Pyoderma gangrenosum (PG) is a systemic disease that presents with cutaneous necrotizing ulceration, producing deep necrotic ulcers, usually with a raised, undermined, violaceous border. Treatment typically involves high dose immunosuppressive drugs, but more recently anti-tumour necrosis factor and monoclonal antibodies have been used. Activated protein C (APC) stimulates wound healing ...
Mak Suzanne So-Shan SS Department of Clinical Oncology, Prince of Wales Hospital, Hong Kong. Electronic address: - - 2014
Wound cleansing should create an optimal healing environment by removing excess debris, exudates, foreign and necrotic material which are commonly present in the wounds that heal by secondary intention. At present, there is no research evidence for whether pressurised irrigation has better wound healing outcomes compared with conventional swabbing practice ...
Jordan Martin C - - 2014
BackgroundBarbed suture material offers the possibility of knotless flexor tendon repair, as suggested in an increasing number of biomechanical studies. There are currently two different absorbable barbed suture products available, V-Loc¿ and Stratafix¿, and both have not been compared to each other with regard to flexor tendon repair. The purpose ...
Zhao Song S Department of Orthopaedics, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, P. R. - - 2014
Rotator cuff tears (RCTs) are a common cause of shoulder pain and disability in middle and older age. Despite improvements in the understanding of this disease process and advances in surgical treatment, rotator cuff (RC) repair failure rates remain high. Insufficient healing capacity is likely the main factor for failure ...
Fox Alice J S AJ Laboratory for Soft Tissue Research, Hospital for Special Surgery, New York, New York, USA foxa@hss.edu - - 2014
Recent studies suggest that fluoroquinolone antibiotics predispose tendons to tendinopathy and/or rupture. However, no investigations on the reparative capacity of tendons exposed to fluoroquinolones have been conducted. Fluoroquinolone-treated animals will have inferior biochemical, histological, and biomechanical properties at the healing tendon-bone enthesis compared with controls. Controlled laboratory study. Ninety-two rats ...
Nitzschke Stephanie L SL From the *U.S. Army Institute of Surgical Research, Fort Sam Houston, Texas;†Uniformed Services University for the Health Sciences, Bethesda, Maryland; ‡Naval Medical Research Unit-San Antonio, Fort Sam Houston, Texas; §University of Texas Health Science Center at San - - 2014
The rate of wound healing and its effect on mortality has not been well described. The objective of this article is to report wound healing trajectories in burn patients and analyze their effects on in-hospital mortality. The authors used software (WoundFlow) to depict burn wounds, surgical results, and healing progression ...
Bene M Del MD S. Gerardo Hospital, Department of Plastic, Hand Surgery and Reconstructive Microsurgery, Monza, - - 2014
Background: Digital ulcers (DUs) occur in up to 50% of patients with Systemic Sclerosis (SSc). DUs are painful, recurring and lead to functional disability. Management of DUs includes pharmacologic and local therapy, the healing process is slow and the ulcer can become infected or evolve to gangrene. Autologous fat grafting ...
Yu Myeong Sang MS Department of Otolaryngology, Konkuk University School of Medicine, Chungju, - - 2014
The purpose of this study was to investigate the effect of aerosolized fibrin sealant (FS) compared with that of polyvinyl acetal sponge packing on hemostasis and wound healing after functional endoscopic sinus surgery (FESS). We conducted a prospective randomized controlled trial of the use of aerosolized FS in 41 consecutive ...
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