Search Results
Results 1 - 50 of 2278
1 2 3 4 5 6 7 8 9 10 >
Strong Amy L AL From the *Center for Stem Cell Research and Regenerative Medicine, Tulane University, School of Medicine, New Orleans, Louisiana; and †Baton Rouge General Medical Center, - - 2014
The treatment of full thickness skin wounds commonly associated with large burns continues to represent a challenging clinical entity. The current treatment for large TBSA burns is split thickness autologous skin grafting; however, this treatment often results in poor textural durability, hypertrophic scarring, and fibrotic contractures. In this case report, ...
Mori Hirohito H Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Kita-gun, Miki-cho, Kagawa, 761-0793, Japan, - - 2014
Comparative studies on wound surface treatments after endoscopic mucosal resection (EMR) of 10- to 20-mm colorectal polyps have not been reported. We conducted a prospective trial of postoperative hemorrhage prevention measures after EMR of such polyps. Of 138 patients (397 polyps) who had undergone EMR, 62 patients (148 polyps) with ...
Jockenhöfer Finja F Department of Dermatology, Venereology and Allergology, University Hospital of Essen, Essen, - - 2014
Numerous comorbidities and cofactors have been known to influence wound healing processes. In this multicentre study, clinical data of 1 000 patients with chronic leg ulcers from ten specialised dermatological wound care centers were analysed. The patient cohort comprised 567 females and 433 males with an average age of 69·9 years. The ...
Kwon Chang-Il CI Digestive Disease Center, CHA University, Seongnam, Republic of - - 2014
Various bio-sheet grafts have been attempted either to accelerate healing of artificial ulcers or to prevent adverse events after endoscopic submucosal dissection (ESD), but neither prospective nor mechanistic studies were available. To evaluate the substantial effect of a bio-sheet graft on artificial ulcer healing and its feasibility as an endoscopic ...
Zhang Wei - - 2014
BackgroundThe aim of this study is to evaluate the effects of tourniquet release before wound closure for hemostasis or after wound closure in cemented total knee arthroplasty (TKA).MethodsWe conducted a meta-analysis and review work on relevant clinical outcomes to evaluate the effects of the timing of tourniquet release in cemented ...
Nolff M C MC Dr. Mirja Christine Nolff, Ludwig-Maximilians-University, Clinic for Small Animal Surgery and Reproduction, Veterinärstrasse 13, 80539 Munich, Germany, E-mail: - - 2014
Objectives: To evaluate negative pressure wound therapy (NPWT) for treatment of complicated wounds in dogs. Study type: Retrospective multicentre study. Materials and methods: Dogs (n = 50) undergoing open wound treatment were classified according to treatment method used: bandage (Group A, n = 7), NPWT (Group B, n = 18), ...
Taniguchi Noboru N Department of Orthopaedic Surgery, University of Miyazaki, Miyazaki, Japan; Institute of Medical Science, Tokyo Medical University, Tokyo, Japan. Electronic address: - - 2014
Bone marrow stimulation (BMS) at the footprint of arthroscopic rotator cuff repair has not been fully evaluated according to the preoperative tear size and surgical technique. In this study, we investigated the effect of BMS on cuff repair integrity after an arthroscopic surface-holding (ASH) repair. A total of 111 patients ...
Biter L Ulas LU Sint Franciscus Gasthuis, Department of Surgery, Rotterdam, the - - 2014
Pilonidal sinus disease is associated with significant morbidity after surgical treatment with regard to wound healing. Recent case studies suggested that negative-pressure wound therapy as primary treatment following surgical excision may shorten the duration of wound healing. The purpose of this randomized controlled trial was to evaluate the role of ...
Toledo-Piza Ana Rita de AR Ana Rita de Toledo-Piza, PhD, is a Postdoctoral Scientist, and Durvanei Augusto Maria, PhD, MSc, is a Scientific Researcher; both at the Laboratory of Biochemistry and Biophysics, Butantan Institute, São Paulo, - - 2014
Phyllocaulis boraceiensis mucus has been studied as a potential source of new natural compounds that are capable of inducing proliferation and remodeling tissue. The aim of this study was to evaluate the clinical aspects of healing in the wounded mouse skin, which was treated with an ointment that was composed ...
Conway Janet D - - 2014
The authors compared the results of treating nonunion with either bone morphogenetic protein (BMP)-7 or BMP-2. Between 2001 and 2009, 214 limb segments were treated for nonunion with either BMP-7 or BMP-2 at the authors' institution. Sixty-three subjects received 76 units of BMP-7. Radiographic healing occurred in 70% of limb ...
Kempton Laurence B LB 1Carolinas Medical Center, Department of Orthopaedic Surgery 2Carolinas Medical Center, Department of General - - 2014
1. To determine whether negative pressure dressings (NPD) are superior to conventional compressive dressings (CD) for split-thickness skin grafts (STSG) placed on healthy, low-risk wounds. 2. To determine cost difference of NPD versus CD. Retrospective SETTING:: Level I Trauma Center PATIENTS/PARTICIPANTS:: 195 traumatic wounds treated with STSG. Patients were assigned ...
Karanasos Antonios A Department of Interventional Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, the - - 2014
Although recent observations suggest a favorable initial healing process of the everolimus-eluting bioresorbable vascular scaffold (BVS), little is known regarding long-term healing response. This study assessed the in vivo vascular healing response using optical coherence tomography (OCT) 5 years after elective first-in-man BVS implantation. Of the 14 living patients enrolled in the ...
Tracey Alexandra K AK Department of Veterinary Clinical Sciences College of Veterinary Medicine (Tracey, Alcott, Schleining, Safayi, Hostetter, Reinertson), and Department of Genetics, Development, and Cell Biology (Zaback), Iowa State University, Ames, Iowa 50011, - - 2014
Topical oxygen therapy (TOT) has been used in human medicine to promote healing in chronic wounds. To test the efficacy and safety of TOT in horses, an experimental wound model was created by making 1 standardized dermal wound on each limb of 4 healthy horses (n = 16). Each wound ...
Fenech M M Higher Specialist - - 2014
Guidelines for swab use at our centre cover lower-limb wounds, ulcers and postoperative wound infections but not all types of wound. The objective of this study was to assess current practices in wound management at Mater Dei Hospital and to identify areas for improvement. Wound swabs received at the microbiology ...
Xie Youzhuan Y Shanghai Key Laboratory of Orthopaedic Implant, Department of Orthopaedic Surgery, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200011, People's Republic of - - 2014
A variety of bone substitutes have been successfully used to fill PEEK cages in cervical interbody fusion in order to avoid the complications related to bone harvesting from the donor site. However, no controlled study has previously been conducted to compare the effectiveness of PEEK interbody cages containing calcium sulphate/ ...
Zelen Charles M CM Professional Education and Research Institute, Roanoke, VA, - - 2014
A prospective, randomised, controlled, parallel group, multi-centre clinical trial was conducted at three sites to compare the healing effectiveness of treatment of chronic lower extremity diabetic ulcers with either weekly applications of Apligraf® (Organogenesis, Inc., Canton, MA), EpiFix® (MiMedx Group, Inc., Marietta, GA), or standard wound care with collagen-alginate dressing. ...
Stahl Hans-Christian - - 2014
BackgroundA previously published proof of principle phase IIa trial with 113 patients from Kabul showed that bipolar high-frequency (HF) electro-cauterization (EC) of cutaneous leishmaniasis (CL) ulcers and subsequent moist wound treatment (MWT) closed 85% of all Leishmania (L.) tropica lesions within 60 days.MethodsA three-armed phase IIb, randomized and controlled clinical trial ...
Nzanzu J J Bruxelles, - - 2014
Autologous iliac crest bone graft has been long considered the gold standard for spine fusion but is associated with various adverse effects. New sources, such as adipose derived mesenchymal stem cells (AMSCs) have recently emerged and demonstrated to be an alternative for bone tissue engineering. Our purpose is to analyze ...
Arai Makoto M Makoto Arai, Tomoaki Matsumura, Kenichiro Okimoto, Arata Oyamada, Keiko Saito, Shoko Minemura, Daisuke Maruoka, Takeshi Tanaka, Tomoo Nakagawa, Tatsuro Katsuno, Osamu Yokosuka, Department of Gastroenterology and Nephrology (K1), Graduate School of Medicine, Chiba University, Chiba 260-8670, - - 2014
To investigate the optimum period of treatment for post endoscopic submucosal dissection (ESD) ulcers. Patients who underwent ESD for gastric cancer were randomized to two groups and treated with esomeprazole 20 mg per day for 4 wk (4W group) or 2 wk (2W group). At 4 wk after ESD, we ...
Banov Daniel D Professional Compounding Centers of America (PCCA), 9901 South Wilcrest Drive, Houston, TX, 77099, USA, - - 2014
Wounding affects the integrity of the skin and can ultimately result in skin scarring. Current therapeutic goals of wound treatment focus on the reduction of scar formation and severity. However, scar formation itself varies not only between individuals based on factors such as ethnicity, but also within an individual based ...
Singer Adam John AJ Department of Emergency Medicine, Stony Brook University, Stony Brook, New - - 2014
Minor abrasions and skin tears are usually treated with gauze dressings and topical antibiotics requiring frequent and messy dressing changes. We describe our experience with a low-cost, cyanoacrylate-based liquid dressing applied only once for minor abrasions and skin tears. We conducted a single-center, prospective, noncomparative study in adult emergency department ...
Gokce S M SM Dental Sciences Centre, Department of Orthodontics, Gulhane Military Medical Academy, Etlik, Ankara, Turkey. Electronic address: - - 2014
The aim of this study was to evaluate the effects of local administration of human amniotic fluid (HAF) on newly formed bone obtained by mandibular distraction osteogenesis (DO) with histomorphometry. A unilateral mandibular osteotomy at the left corpus was performed in 32 adult male rabbits. After a 5-day latency period, ...
Ma Wen-Jie WJ Wen-Jie Ma, Yong Zhou, Rui-Hua Xu, Anuj Shrestha, Fu-Yu Li, Alex Lorance, Qin Yang, Yong-Qiong Zhang, Ting Jiang, Huan Feng, Nan-Sheng Cheng, Department of Hepatobiliary Surgery, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, - - 2014
To compare the effectiveness of needle-free incision suture closure with butterfly tape and traditional secondary suturing techniques in treating incision infection. Two hundred and twenty-three patients with incision infection following hepatobiliary surgery at a tertiary hospital were randomly divided into three groups: 90 patients were closed by needle-free incision suture ...
Kubota Akio A Department of Pediatric Surgery, Osaka Medical Center and Research Center for Maternal and Child Health, 840 Murodo-cho, Izumi, Osaka, 594-1101, Japan, - - 2014
Our previous experimental study of perforated peritonitis in rats proved that peritoneal lavage with strong acid electrolyzed water (SAEW) has no adverse effects, reduces the bacteria count in the ascitic fluid more effectively than saline, and increases the survival rate significantly. Thus, we conducted a randomized controlled study, applying SAEW ...
Calder James D F JD Chelsea & Westminster Hospital, London, UK Fortius Clinic, London, - - 2014
Achilles tendinopathy is a serious and frequently occurring problem, especially in elite athletes. Recent research has suggested a role for the plantaris tendon in non-insertional Achilles tendinopathy. To assess whether excising the plantaris tendon improved the symptoms of Achilles tendinopathy in elite athletes. This prospective consecutive case series study investigated ...
Kojima Sachi S Department of Ophthalmology, Kumamoto University, Kumamoto, - - 2014
Posttrabeculectomy changes in bleb parameters measured using 3-dimensional (3-D) anterior-segment optical coherence tomography (OCT) remain uncharacterized and might be related to postsurgical intraocular-pressure (IOP) control. To evaluate time-dependent posttrabeculectomy changes in filtering bleb parameters using 3-D anterior-segment OCT. This prospective observational study was conducted at Kumamoto University Hospital, Kumamoto, Japan. ...
Lou Zhengcai Z Department of Otorhinolaryngology, The Affiliated YiWu Hospital of Wenzhou Medical College , Yiwu , - - 2014
Abstract Objective: The aim of this study was to determine the optimum time for direct application of basic fibroblast growth factor (bFGF) on large traumatic tympanic membrane perforations (TMPs). Study design: Prospective clinical study. Setting: Tertiary University Hospital. Methods: Ninety-three patients, with traumatic TMPs greater in extent than 25% of ...
Dias Stephanie Botti Fernanandes SB Division of Periodontics, College of Dentistry - FOSJC, UNESP - State University of São Paulo, Av. Eng. Francisco José Longo, 777, São José dos Campos, SP, 12245-000, - - 2014
Among the available techniques to treat gingival recession, connective tissue graft (CTG) presents more foreseeability and better results in the long term. However, this technique causes morbidity and discomfort in the palatine region due to graft removal at that site. The aim of this clinical trial was to evaluate the ...
Käser S A SA Department of General, Visceral, Vascular, and Thoracic Surgery, Hospital of Baselland, affiliated to the University of Basel, Rheinstrasse 26, 4410, Liestal, - - 2014
Off-midline procedures seem to be the best method of primary wound closure after excision of a pilonidal sinus. Primary wound closure with a Limberg flap was compared to secondary wound healing. From January 2006 to July 2012, 102 patients with given informed consent (mean age 28 years, men 81 %) who had ...
Joo Jayne J Department of Dermatology, University of California Davis Medical Center, - - 2014
Purse-string suture is a closure method that purportedly reduces the scar area compared with second intention healing. Randomized clinical trials comparing these 2 methods appear to be limited or absent. To determine if purse-string suture improves cosmetic outcome, healing time, and scar to defect area compared with second intention healing ...
Mintline Erin M EM Department of Animal Science, University of California, Davis, USA, - - 2014
Previous studies have shown that surgical castration wounds take between 10 and 61 d to heal. The objectives of this work were to describe healing, inflammation, lying behavior and serum concentration of substance P after surgical castration in beef calves and to evaluate the effect of a possible intervention, a ...
Filippelli Sergio S Department of Pediatric Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital, IRCCS, Rome, - - 2014
To analyze the effectiveness and the results of the use of a vacuum-assisted closure (VAC) system for the treatment of complex sternal wounds in newborns after cardiac surgery. From May 2008 until December 2012, six patients developed post-sternotomy wound problems (large defects of epithelialization or mediastinitis), which were treated with ...
Hall Barry J BJ aDepartment of Gastroenterology, Adelaide and Meath Hospital bDepartment of Gastroenterology, St James's Hospital, Dublin, - - 2014
Mucosal healing is increasingly recognized as an important treatment goal in Crohn's disease (CD). Data from colonic disease shows improved long-term outcomes in patients achieving complete mucosal healing. Little is currently known of this with respect to ileitis, which is increasingly diagnosed using small bowel capsule endoscopy. The study aimed ...
Su Zhongchun Z Institute of Biomedicine, National Engineering Research Center of Genetic Medicine, Key Lab for Genetic Medicine of Guangdong Province, Jinan University, Guangzhou 510632, - - 2014
Current therapy for skin wound healing still relies on skin transplantation. Many studies were done to try to find out ways to replace skin transplantation, but there is still no effective alternative therapy. In this study, decellularized scaffolds were prepared from pig peritoneum by a series of physical and chemical ...
van Leen M M Avoord Zorg en Wonen, Etten-Leur, the - - 2014
To record and assess the application and the progression of wound healing in patients who received Sorbion sachet S or Sorbion Sana wound dressings. A convenience sample of patients with chronic wounds was recruited from nursing homes or community wound clinics in the Netherlands and the UK. Wound surface area ...
Stephen-Haynes J J Professional Development Unit, Birmingham City - - 2014
This article assesses the use of BeneHold Thin Absorbent Skin Adhesive (TASA) wound dressings in a large UK primary care organisation. These wound dressings are thin (0.12mm), breathable, transparent, and are able to absorb and retain wound exudate. This non-comparative evaluation was undertaken to explore the clinical advantages this differentiated ...
You H J HJ Clinical Instructor, Department of Plastic Surgery, Korea University College of Medicine, Seoul, - - 2014
Diabetic foot ulcers (DFUs) often pose a treatment problem. Bioengineered skin substitutes have been reported to result in accelerated diabetic wound healing. The purpose of this clinical trial was to evaluate the efficacy and safety of the autologous fibroblast-hyaluronic acid complex for treating DFUs. A stratified, randomised, controlled, multicentre study ...
Habesoglu Mehmet M From the Department of Otorhinolaryngology, Umraniye Training and Research Hospital, Istanbul, - - 2014
Our objective was to demonstrate the effects of platelet-rich fibrin (PRF) for the healing of acute ear drum perforation. Thirty-two patients with acute traumatic ear drum perforations were randomly separated into 2 groups. In group 1 (n = 14), PRF was used for the repair of ear drum perforation; in ...
Norris Ray R Clinical Nurse Specialist, Tissue Viability, South West Essex Community Services, North East London NHS Foundation - - 2014
Acute wounds will generally heal independently of any interventions, whereas chronic wounds are chronic for a reason and are unlikely to successfully heal without intervention. In the treatment of venous leg ulcers, the gold standard will always be compression therapy. However, many wounds still do not heal despite best practice. ...
Cai Elijah Zhengyang EZ Department of Surgery, National University Health System, - - 2014
The combination of polycaprolactone and hyaluronic acid creates an ideal environment for wound healing. Hyaluronic acid maintains a moist wound environment and accelerates the in-growth of granulation tissue. Polycaprolactone has excellent mechanical strength, limits inflammation and is biocompatible. This study evaluates the safety and efficacy of bio-conjugated polycaprolactone membranes (BPM) ...
Loaec E E Service ORL-CCF, hôpital d'instruction des armées Clermont-Tonnerre, rue Colonel-Fontferrier, CC 41, 29241 Brest, France. Electronic address: - - 2014
Pharyngocutaneous fistula is a well-known complication of head and neck cancer surgery. The purpose of this study was to determine the value of negative-pressure wound therapy (NPWT) for the treatment of these fistulas. NPWT is used in many fields of medicine, but its use in otorhinolaryngology has been rarely reported. ...
Kim Hyun Woo HW *Department of Dermatology, Hanyang University College of Medicine, Seoul, Korea; †Department of Dermatology, Asan Medical Center, Seoul, - - 2014
Because acne scarring is associated with substantially reduced quality of life, early initiation of effective treatment is desirable. In previous reports, isotretinoin treatment was associated with increased scarring after cosmetic procedures, such as laser treatment, dermabrasion, and chemical peeling. To evaluate wound healing after ablative carbon dioxide (CO2) fractional resurfacing ...
Inan Bekir - - 2014
IntroductionStraight sternotomy is the most common access for open heart surgery. Techniques have been proposed for maximizing sternal stability in high-risk patients. This trend implies a growing need for newer surgical techniques. The aim of this experimental study in the sheep model is to evaluate median vs. S shaped sternotomy ...
Akinci Melih M Department of General Surgery, Diskapi Teaching and Research Hospital, Ankara, 06110, Turkey. Electronic address: - - 2014
Background: The effect of the timing of the second laparotomy on wound healing is not clear. In an experimental study in rats, we aimed to investigate the effect of timing on wound healing after reoperations on the same surgical site. Material and methods: Forty-eight rats were divided into four groups. ...
Wang Lian-Zhao LZ *All the authors are affiliated with Department of Plastic and Reconstructive Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, - - 2014
Chest keloids are challenging to surgeons because of their high recurrence rate. To investigate the effectiveness of the subcutaneous super-tension-reduction suture technique with postoperative electron-beam irradiation in the treatment of chest keloids. Forty-five patients with chest keloids underwent excision. To minimize the wound-closing tension, subcutaneous super-tension-reduction suture was used. The ...
Calori G M GM C.O.R. Reparative Orthopaedic Surgery Department, Orthopaedic Institute Gaetano Pini, University of Milan, Italy. Electronic address: - - 2014
Non-union of long bones is a significant consequence of fracture treatment. The ideal classification for non-union of long bones would give sufficient significant information to the orthopaedic surgeon to enable good management of the treatment required and to facilitate the creation of comparable study groups for research purposes. The Non-Union ...
Sarıtaş Tuba Berra TB Department of Anesthesiology and Reanimation, Meram Medical School, Necmettin Erbakan University, Konya, - - 2014
Gabapentinoids are effective adjunct drugs for reducing postoperative pain. However, the effects of gabapentinoids on wound healing have not been evaluated yet. In this study we evaluated their effects on wound healing. A total of 17 male Wistar-Albino rats, 250-350 g, were divided into three groups randomly: control group (n = 5, 2 ml ...
Grover G G Department of Vascular Surgery, Derriford Hospital, Plymouth, UK - - 2014
Ultrasound-guided foam sclerotherapy is a minimally invasive treatment option used for ablation of axial and perforator reflux for chronic venous ulceration. Active ulceration presents a significant health burden in both the primary and secondary care setting. The objective of this study is to determine ulcer healing rates at 24 weeks ...
Demetrashvili Zaza Z Department of Surgery of Tbilisi State Medical University, 33, Vazha-Pshavela ave., 0177 Tbilisi, Georgia; Department of General Surgery of Kipshidze Central University Hospital, 29, Vazha-Pshavela ave., 0160 Tbilisi, Georgia. Electronic address: - - 2014
Purpose: The aim of the present clinical study was to compare early and late outcomes after inguinal hernia repair with the heavyweight mesh (HW) and lightweight mesh (LW) during a 3 year follow-up period. Methods: 226 patients were randomized into LW and HW mesh groups, both of which underwent unilateral ...
Gwak Heui-Chul HC Department of Orthopaedics, Busan Paik Hospital, College of Medicine, Inje University, Busan, South - - 2014
The purpose of this study was to evaluate the extension of delamination and the cuff integrity after arthroscopic repair of delaminated rotator cuff tears. Sixty-five patients with delaminated rotator cuff tears were retrospectively reviewed. The delaminated tears were divided into full-thickness delaminated tears and partial-thickness delaminated tears. To evaluate the ...
1 2 3 4 5 6 7 8 9 10 >