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Bene M Del MD S. Gerardo Hospital, Department of Plastic, Hand Surgery and Reconstructive Microsurgery, Monza, - - 2014
Background: Digital ulcers (DUs) occur in up to 50% of patients with Systemic Sclerosis (SSc). DUs are painful, recurring and lead to functional disability. Management of DUs includes pharmacologic and local therapy, the healing process is slow and the ulcer can become infected or evolve to gangrene. Autologous fat grafting ...
Yu Myeong Sang MS Department of Otolaryngology, Konkuk University School of Medicine, Chungju, - - 2014
The purpose of this study was to investigate the effect of aerosolized fibrin sealant (FS) compared with that of polyvinyl acetal sponge packing on hemostasis and wound healing after functional endoscopic sinus surgery (FESS). We conducted a prospective randomized controlled trial of the use of aerosolized FS in 41 consecutive ...
Baillargeon Emilie E Division of Urology, McGill University, Montreal, - - 2014
We sought to determine whether the use of preoperative antibiotics is effective in reducing postoperative wound infections and urinary tract infections (UTI) in hypospadias repair. We retrospectively reviewed all hypospadias repairs performed at the Montreal Children's Hospital between March 2009 and September 2012. All types of primary hypospadias repairs and ...
Hemmati Ali Asghar AA School of Pharmacy, The Physiology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR - - 2014
Wound healing is a complicated and integrated process. Researches have indicated the wound healing effects of calcium channel blockers in animal models in recent years. The aim of this study was to evaluate the wound-healing activity of amlodipine as a calcium channel blocker and combination of amlodipine with phenytoin on ...
Mohajeri Gholamreza G Department of Thoracic Surgery, Isfahan University of Medical Sciences, Isfahan, - - 2014
Kiwifruit (Actindia Deliciosa) is demonstrated to have antibacterial and pro-angiogenic effects. It also contains proteolytic enzymes (actinidin) and ascorbic acid. In this study, the effects of Kiwifruit on neuropathic diabetic foot ulcer healing in clinical settings were evaluated. In this randomized clinical trial of 37 patients (17 in experimental and ...
You Tae-Min TM Assistant Professor, Department of Advanced General Dentistry, Dental Hospital, Dankook University, Cheonan, South - - 2014
To evaluate the change in mandibular second-molar (M2) angulation in orthodontic treatment with premolar extraction and lower third molar (M3). Panoramic radiographs were evaluated in 3 groups of 129 participants: (1) control, no orthodontic treatment (n = 65); (2) extraction, orthodontic treatment with premolar extraction (n = 30); and (3) nonextraction, orthodontic ...
Honnegowda Thittamaranahalli Muguregowda TM Department of Plastic Surgery and Burns, Kasturba Medical College, Manipal, Karnataka, - - 2014
Healing ability of nonhealing chronic ulcers can be assessed by estimating hydroxyproline, total protein and enzymatic antioxidants such as glutathione peroxidase (GPx), glutathione S-transferase (GST) in the granulation tissue. A total of 34 patients were analysed from two groups: Limited access dressing (LAD) group (n = 17) and conventional dressing ...
Samuels Joshua J Dept. of Biomedical Eng., Drexel Univ., Philadelphia, - - 2014
We report the results of a second clinical pilot study (n = 19) involving treatment of chronic wounds (venous ulcers) using novel, fully wearable ultrasound array applicator operating at 20 kHz and generating pressure amplitudes close to 55 kPa (about 100 mW/cm(2), Sptp). The applicator was designed as compact, tether-free, device that ...
Alsalleeh Fahd F Department of Surgical Specialties, College of Dentistry, University of Nebraska Medical Center, Lincoln, Nebraska; Department of Restorative Dental Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia. Electronic address: - - 2014
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a well-known complication caused by amino-bisphosphonate therapy. We document one case of BRONJ associated with oral administration of methotrexate, a known immunosuppressive drug used to treat rheumatoid arthritis. A 66-year-old woman was referred for evaluation and endodontic surgery of recently re-treated tooth 13. ...
MacFarlane Robert J RJ Department of Trauma and Orthopaedics, Macclesfield District General Hospital, East Cheshire NHS Trust, Victoria Road, Macclesfield SK10 3BL, - - 2014
Introduction. Debate exists amongst surgeons regarding the ideal suture material for skin closure in carpal tunnel decompression (CTD). This study compares wound related complications, patient satisfaction, and functional outcome following open carpal tunnel decompression in patients undergoing wound closure with either of two common absorbable and nonabsorbable suture types. Materials ...
Khater Mohammad M MM Ophthalmology Department, Tanta University Hospital, Tanta, El Gharbia Governorate, - - 2014
The purpose of this study was to evaluate the effect of use of contact lenses to improve visual outcome after repair of traumatic corneal wounds. Two groups of patients (n=30 each) with traumatic full thickness corneal wounds were entered into this study. All cases were caused by sharp objects such ...
Lindner Tobias T Department of Orthopaedics, University Medicine Rostock, 18057 Rostock, - - 2014
Numerous studies have shown reduction of periprosthetic bone mineral density (BMD) after hip replacement. The effect on the whole limb, however, is still unexplored. This study's objective was to analyse the postoperative development of BMD and muscle strength of the limb after total hip replacement (THR) and to determine links ...
D'Aquino S - - 2013
Preharvest infections or conidia load on fruit surface by Penicillium digitatum, P. italicum, Alternaria citri and other filamentous fungi can cause important postharvest losses of citrus fruit. Reduction in pruning frequency occurred in the last decade together with un-picked yield that eventually rots on the trees have increased the risk ...
Asplund D - - 2012
Extralevator abdominoperineal excision (APE) for low rectal tumours has been introduced to achieve improved local radicality. Fewer positive margins and intraoperative perforations have been reported compared with standard APE. The aim of this retrospective study was to compare short-term complications and results of the two techniques in our institution. Consecutive ...
Dhanani Jayesh J Department of Intensive Care Medicine, Prince Charles Hospital, Brisbane, Queensland, Australia. - - 2013
The study objective was to investigate the effect of renal failure on intermediate-term survival in cardiac surgery patients. All patients aged 18 years or older undergoing coronary artery bypass grafting, valvular surgery, thoracic aortic surgery, or a combination of these from January 1, 2002 to December 1, 2005 were included. ...
Buethe David D - - 2012
PURPOSE: We evaluated the ability of renal tumor complexity, as assessed by the R.E.N.A.L. (radius, exophytic, nearness to collecting system, anterior/posterior and location) nephrometry scoring system, to predict the functional efficacy of nephron sparing surgery. MATERIALS AND METHODS: We evaluated 42 patients who presented with an anatomically (32) or a ...
Chou Yu-Hsiang - - 2012
Relatively little is known about the long-term outcomes of different histologic types of primary glomerulonephritis in Asian populations. From 1993 to 2006, 987 patients undergoing renal biopsy were studied, and 580 patients (mean age=44.4 years, male=58.5%) with the four most common forms of glomerulonephritis (membranous nephropathy, focal and segmental glomerulosclerosis, ...
Gulati Sonia S College of nursing, AIIMS, New Delhi, 110029 - - 2014
To compare the healing of chronic wounds with honey dressing vs. Povidone iodine dressing in adult subjects with chronic wounds of ≥6 weeks of duration, attending wound care clinic in Surgical Out Patient Department of All India Institute of Medical Sciences, Surgical Out Patient Department of Jai Prakash Narayan Apex Trauma ...
Wada Yukihiro Y Nephrology Department of Internal Medicine, Showa University Northern Yokohama Hospital, Chigasaki-chuo 35-1, Tsuzuki, Yokohama 224-8503, Japan. - - 2013
Immunoglobulin (Ig) A nephropathy (IgAN) is characterized by mesangial deposits of IgA1 and C3, often with co-deposits of IgG. We attempted to clarify the clinical significance of mesangial IgG deposition in patients with IgAN. We retrospectively reviewed 57 patients who were diagnosed with IgAN on the basis of pathological examination ...
Tiryaki Sibel - - 2012
OBJECTIVE: To evaluate the clinical course of multicystic dysplastic kidney (MCDK) and to reveal any criteria indicating spontaneous involution. MATERIAL METHODS: Hospital records of patients with MCDK followed in two different institutions in 1994-2009 were reviewed and data were analyzed regarding involution. RESULTS: Records of 96 patients were reviewed, of ...
Jiang Wen-Ling - - 2012
Objective: To explore the association of urinary podocyte excretion and renal expression of podocyte-specific marker podocalyxin (PCX) with clinicopathological changes in immunoglobulin A nephropathy (IgAN). Methods: Morning urine samples from IgAN patients and healthy controls were collected. The expression of glomerular PCX was quantified in 50 IgAN patients diagnosed by ...
Kawamura Tetsuya - - 2012
Background: A multicenter case-control study on IgA nephropathy (IgAN) was conducted to develop an evidence-based clinicopathologic classification of IgAN for predicting long-term renal outcome. Methods: Two hundred and eighty-seven patients including those with isolated hematuria or very mild proteinuria were enrolled. During a median follow-up of 9.3 years after biopsy, ...
Tsuboi Kazuya K Department of Hematology, Nagoya Central Hospital, Nagoya, Japan. - - 2012
Fabry disease is a rare, X-linked, inherited lysosomal storage disorder that can be treated with the enzymes agalsidase alfa (Replagal) and agalsidase beta (Fabrazyme). Currently, there is a global shortage of agalsidase beta, and this has increased global demand for agalsidase alfa. We assess the feasibility of switching patients on ...
Maeda Isseki - - 2012
BACKGROUND: Indication of tonsillectomy in IgA nephropathy is controversial. The purpose of this study was to examine the efficacy of tonsillectomy on remission and progression of IgA nephropathy.METHODS: We conducted a single-center 7-year historical cohort study in 200 patients with biopsy-proven IgA nephropathy. Study outcomes were clinical remission defined as ...
Abbas Ahmed - - 2012
BackgroundPrevious studies have demonstrated that fibrates have an effect on creatinine concentrations. The pattern of change with fibrates in estimated glomerular filtration rate (eGFR), widely used in clinical practice, has not been previously described.MethodsData was retrospectively collected from 132 consecutive case notes of patients started on fibrates in a lipid ...
Simmons Matthew N - - 2012
PURPOSE: We used what is to our knowledge a new method to estimate volume loss after partial nephrectomy to assess the relative contributions of ischemic injury and volume loss on functional outcomes. MATERIALS AND METHODS: We analyzed the records of 301 consecutive patients who underwent conventional partial nephrectomy between 2007 ...
Nakasone Yutaka - - 2012
BackgroundPotential drawbacks of percutaneous radiofrequency ablation (RFA) for renal cell carcinoma (RCC) include local recurrence after RFA due to a limited ablation area, massive hemorrhage induced by kidney puncture, and difficulty in visualizing the tumor at CT-guided puncture.PurposeTo evaluate retrospectively the technical success, effectiveness, and complications elicited in patients with ...
Deville Jason - - 2012
Abstract The National Kidney Foundation's (NKF) Kidney Disease Outcomes Quality Initiative (KDOQI) definition of chronic kidney disease (CKD), stages 3-5, requires 2 estimated glomerular filtration rates (eGFRs) <60 ml/min/1.73 m(2) more than 3 months apart. By requiring 2 eGFRs, the NKF definition reduced identification of people without chronic disease, which may have ...
Tan Wah Lay - - 2012
Removal of teeth results in both horizontal and vertical changes of hard and soft tissue dimensions. The magnitude of these changes is important for decision-making and comprehensive treatment planning, with provisions for possible solutions to expected complications during prosthetic rehabilitation. To review all English dental literature to assess the magnitude ...
Taunton Michael J - - 2012
Pelvic discontinuity is an increasingly common complication of THA. Treatments of this complex situation are varied, including cup-cage constructs, acetabular allografts with plating, pelvic distraction technique, and custom triflange acetabular components. It is unclear whether any of these offer substantial advantages. We therefore determined (1) revision and overall survival rates, ...
Joner Michael - - 2012
Despite advances in contemporary stent technology, in-stent restenosis (ISR) remains the major limitation following revascularization procedures. We developed a porcine model of ISR to specifically investigate the preclinical outcomes of a novel drug-eluting balloon (DEB) in this particular setting. Fifteen pigs received bare metal stents in each of the major ...
Park Jin-Young - - 2012
PURPOSE: The follow-up results of bony union after an arthroscopic bony Bankart repair have not been reported. We studied follow-up computed tomography (CT) arthrograms to evaluate radiographic healing of bony Bankart fragments. METHODS: Among 41 patients who underwent arthroscopy for a bony Bankart lesion between July 2006 and May 2009, ...
Chellan G - - 2012
Aim:  To test the hypothesis that fluconazole plus standard care is superior to the standard care for diabetic foot wounds infected with deep-seated fungal infections. Methods:  We carried out a randomized, controlled, open-label, parallel-arm study in 75 patients with both fungal and bacterial infections in deep tissues of diabetic foot ...
Pasek Jarosław - - 2012
Chronic venous insufficiency, as well as crural vein ulceration, developing at its background, poses a serious clinical problem. Treatment is costly and lengthy. Intense development of physical medicine allows to reduce the time of treatment, as well as to improve the life quality in numerous soft tissue ailments, including wounds ...
Henderson James - - 2012
BACKGROUND: Wounds deprived of innervation fail to heal normally, and hypertrophic scars may be abnormally innervated. Manipulation of wounds alters the subsequent degree of scarring, and isoforms of transforming growth factor beta (TGFβ) are well established in this role, whilst TGFβ3 is undergoing clinical trials as an antiscarring agent for ...
Azuma N - - 2012
The aim of the study is to determine factors affecting ischaemic wound healing and role of the angiosome concept in bypass surgery. Single-centre, retrospective clinical study. A total of 249 consecutive critical ischaemic limbs with tissue loss in 228 patients who underwent distal bypasses from 2003 to 2009 were reviewed. ...
Fleissig Yoram - - 2012
A 58-year-old woman presented to the Oral and Maxillofacial Surgery Clinic experiencing severe limited mouth opening and exposed bone in the socket of the right mandibular third molar 8 months following the extraction of the tooth. The patient had been treated during the year before her presentation with sunitinib, an ...
Labropoulos Nicos - - 2012
Plastic surgeons are often approached for wound management and closure of chronic venous ulcers that fail to heal despite multimodal management. The authors present a retrospective analysis of a large series of venous ulcers to determine factors predicting nonhealing and recurrence. Consecutive patients with chronic venous ulcers (≥ 2-cm diameter) ...
Elliott Crb - - 2012
Objective  To report on the outcome of wounds to the hindlimb of racehorses, and horses with the intended use of racing, where both the long digital extensor (LoDE) and lateral digital extensor (LaDE) tendons had been completely transected. Design  Retrospective case series. Methods  Records of all horses admitted with hindlimb ...
Dhar S - - 2012
Conventional open heart surgery with cardiopulmonary bypass (CPB) are associated with transient post-operative renal dysfunction which is caused by systemic inflammatory response induced by CPB. Corticosteroids are administered to attenuate the systemic inflammatory response. The purpose of this study was to compare the effects of pre-bypass and post-bypass methylprednisolone on ...
Walgenbach Klaus J - - 2011
BACKGROUND: Wound drainage and seroma formation following abdominoplasty remain significant concerns to both surgeons and patients due to the resulting increased need for patient follow-up and delays in returning to normal function. While a number of approaches are used to reduce wound drainage and seroma formation, there is still no ...
Jeong Woo-Jin - - 2011
From the oncological point of view, discrimination between the normal healing process and a pathological condition following laser surgery of the larynx is important in the management of possible residual/recurrent disease. However, the wound-healing process following laser surgery of the larynx is not well understood, especially regarding the gross morphological ...
Kim S H - - 2011
This study evaluated the early recovery process of the palatal wounds of dogs using bismuth subgallate. Five healthy adult male dogs underwent eight 5-mm partial-thickness punch biopsies in two paired columns on the palatal mastigatory mucosa. For the haemostasis, one side received moistened gauze pressure (test group 1), and the ...
Opletalová Kristina - - 2011
OBJECTIVE: To study the efficacy of bagged larvae on wound debridement compared with conventional treatment. DESIGN: Randomized, multicenter, controlled, prospective phase 3 trial with blinded assessment of outcome measures by a single observer. SETTING: Two hospital referral centers in Caen and Lyon, France. Patients  Random sampling of 119 patients with ...
Chen Q - - 2011
BACKGROUND: The postoperative scaring, ostial stenosis, and adhesions after functional endoscopic sinus surgery for chronic rhinosinusitis remains a majorproblem. This study was designed to evaluate two new hyaluronan (HA) hydrogels for neo-ostium antistenosis and promoting wound healing in a rabbitmaxillary sinus model.METHODS: The anterior wall of the maxillary sinus of ...
Romero-Cerecero Ofelia - - 2011
The aerial parts of the species AGERATINA PICHINCHENSIS, popularly known as "axihuitl", have been empirically used in Mexico for wound-healing purposes. The evaluation of an extract from A. PICHINCHENSIS (in an IN VIVO model) demonstrated its capacity to reduce, in a significant manner, the time required for wound healing in ...
Carney Christopher M - - 2011
Background: The objective of this study was to compare root defect coverage results and healing responses of bilateral recession defects treated with acellular dermal matrix with and without recombinant human platelet derived growth factor. Methods: Seventeen patients with 40 bilateral gingival recession defects were compared. Each defect was 2 mm ...
Thoma Daniel S - - 2011
AIM: To test whether a collagen matrix (CM) can improve early wound healing and aesthetics, and decrease wound sensitivity compared with spontaneous healing. METHODS: In 15 volunteers, 6-mm punch biopsies were harvested at both palatal sites. A CM was sutured in one site; the other one was left untreated (control). ...
Simsek Serife - - 2011
OBJECTIVE:: The aim of the study is to investigate the effectiveness of the controlled slow-release granulocyte-monocyte colony-stimulating factor (GM-CSF) system in burn wound healing. MATERIAL AND METHODS:: In vivo effect of controlled slow-release GM-CSF from chitosan gel on burn wound healing was evaluated on 18 Wistar-Albino rats, weighing between 250 ...
Siah C J - - 2011
Objective: To perform a comparative assessment of the efficacy of total occlusive ionic silver-containing dressing (TOISD) combination vs no dressing after colorectal surgery. Method: The surgical sites from both groups were swabbed and sent for culture and sensitivity upon wound closure (superficial incisional skin surface) in the operating theatre, as ...
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