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Chen Cheng-Hsu - - 2014
Background/Purpose Retention of excess iron from transfused blood in organs in patients with renal anemia may lead to various systemic complications. Iron chelating agents such as deferasirox (DFX) decrease such iron overload. This study assessed the efficacy, safety, and tolerability of DFX in hemodialysis (HD) patients with iron overload. Methods ...
Heffron Sean P SP Department of Medicine, Leon H. Charney Division of Cardiology, New York University, New York, NY 10016, USA. Electronic address: - - 2014
Obesity, metabolic syndrome (MS) and dyslipidemia are independent risk factors for cardiovascular disease. Bariatric surgery is increasingly recognized as an effective intervention for improving each of these risk factors. There are sparse data on the long-term durability of metabolic changes associated with bariatric surgery, in particular with laparoscopic gastric banding ...
Palmerini Tullio T aDipartimento Cardio-Toraco-Vascolare, Policlinico S. Orsola, Bologna bDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy cColumbia University Medical Center, New York-Presbyterian Hospital, The Cardiovascular Research Foundation, New York, New York, - - 2014
Compared with bare metal stents (BMS), first-generation drug-eluting stents (DES) have significantly reduced the risk of ischemia-driven target vessel revascularization, but have been associated with an increased risk of very late (beyond 1 year) stent thrombosis. Second-generation DES have been developed using different platforms, alternative drugs, and either more biocompatible ...
Larrosa Jose M JM Miguel Servet University Hospital, Instituto Aragonés de Ciencias de la Salud, Zaragoza, - - 2014
To compare the diagnostic performance of different segmentations of the nerve fiber layer (NFL) thickness measurements using an artificial neural network and to define the optimal number of sectors with best diagnostic ability for glaucoma diagnosis. A total of 117 glaucoma patients and 123 normal subjects were included in the ...
Tan Colin Sh CS National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore Fundus Image Reading Center, National Healthcare Group Eye Institute, Singapore, - - 2014
To propose a novel classification system for polypoidal choroidal vasculopathy (PCV), and compare the clinical outcomes among PCV subtypes. Consecutive treatment-naive patients with symptomatic PCV were managed over 5 years. PCV subtypes were classified based on indocyanine green angiography (ICGA) and fluorescein angiography (FA) characteristics. Among 107 patients, 3 PCV subtypes ...
Harris Pamela S PS 1 Kansas City Hospice and Palliative Care , Kansas City, - - 2014
Abstract Objective: To determine whether it is possible to predict, at the time of hospice enrollment, which patients will die within 6 months. Design: Electronic health record-based retrospective cohort study. Setting: Patients admitted to 10 hospices in the CHOICE network (Coalition of Hospices Organized to Investigate Comparative Effectiveness). Participants: Hospice ...
Taenzer Andreas H AH From the *Departments of Anesthesiology and Pediatrics, Children's Hospital at Dartmouth, Lebanon, and The Geisel School of Medicine at Dartmouth, Hanover, New Hampshire; †Department of Anesthesiology, University of Wisconsin School of Medicine and Public Health, American Family Children's Hospital, Madison, Wisconsin; ‡Department of Anesthesiology & Pain Medicine, University of Washington, and Seattle Children's Hospital, Seattle, Washington; §Department of Pediatric Anesthesiology, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University, Chicago, Illinois; ║Departments of Anesthesiology and Pediatrics, Children's Hospital of Colorado, University of Colorado School of Medicine, Aurora, Colorado; #Axio Research, Seattle, Washington; and **Department of Anesthesiology, Pain and Perioperative Medicine, The Lucile Packard Children's Hospital at Stanford, Stanford University, Stanford, - - 2014
The impact of the patient state at time of placement of regional blocks on the risk of complications is unknown. Current opinion is based almost entirely on case reports, despite considerable interest in the question. Analyzing more than 50,000 pediatric regional anesthesia blocks from an observational prospective database, we determined ...
Kwok Chun Shing - - 2014
The usefulness of time-limited consecutive data collection compared to continuous consecutive data collection in conditions which show seasonal variations is unclear. The objective of this study is to assess whether one month of admission data can be representative of data collected over two years in the same hospitals. We compared ...
Mortara Andrea A Department of Clinical Cardiology and Heart Failure, Policlinico di Monza, - - 2014
In the recent Italian Network on Heart Failure (IN-HF) Outcome registry, including 1,855 patients with acute heart failure (AHF), we reviewed the use of inotropes and their prognostic implication on in-hospital and 12-month mortality. IN-HF Outcome is a prospective, multicenter, observational, study involving 61 Italian cardiology centers. AHF patients have ...
Badawy D A DA Infection Control Directorate, Ministry of Health, Kuwait; Infection Control Office, Ibn Sina Hospital, Ministry of Health, Kuwait. Electronic address: - - 2014
Embedding dialysis surveillance scheme is associated with reductions in blood stream infection and antimicrobial consumption .The aim of this study was to establish baseline dialysis events (DE) rates; hospitalization, intravenous (IV) antibiotics start or a positive blood culture stratified by vascular access category and comparisons to published National Healthcare Safety ...
Kim Hun-Sung HS Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. ; Institute of Catholic Ubiquitous Health Care, The Catholic University of Korea, Seoul, - - 2014
We aimed to assess the efficacy of the smartphone-based health application for glucose control and patient satisfaction with the mobile network system used for glucose self-monitoring. Thirty-five patients were provided with a smartphone device, and self-measured blood glucose data were automatically transferred to the medical staff through the smartphone application ...
Koulikov Dmitry D Department of Urology, Roswell Park Cancer Institute, Buffalo, New - - 2014
To determine whether the pattern of low detectable prostate-specific antigen (PSA) during the first 3 years of follow-up after radical prostatectomy (RP) is a predictor for subsequent biochemical recurrence (BCR). An institutional database was queried to identify 1136 patients who underwent open retropubic RP (ORP) or robot-assisted RP (RARP) 1/5/1993 ...
Bowman Jessica L JL Section of Cardiology, Nationwide Children's Hospital, Ohio State University, Columbus, Ohio; Division of Pediatric Cardiology, Mayo Clinic College of Medicine, Rochester, Minnesota. Electronic address: - - 2014
Surgical repair of partial atrioventricular septal defects (AVSD) has been successful for more than 60 years. However, recent data from the Pediatric Heart Network show that 31% of patients have moderate or severe left atrioventricular valve regurgitation (LAVVR) at follow-up. Previously, our institution found that only 9% of patients had more ...
Afghani Elham E Division of Gastroenterology, Johns Hopkins Medical Institutions, Baltimore, Maryland, - - 2014
Background and study aims: Placement of a pancreatic stent is recommended for the prevention of pancreatitis after endoscopic retrograde cholangiopancreatitis (ERCP) among high-risk patients. However, it is not known whether there is a particular feature of the pancreatic stent that is associated with a lower incidence of post-ERCP pancreatitis (PEP). ...
Donnino Michael W MW 1Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA. 2Department of Medicine, Division of Critical Care, Beth Israel Deaconess Medical Center, Boston, MA. 3Research Center for Emergency Medicine, Aarhus University, Aarhus, Denmark. 4Department of Emergency Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA. 5Department of Emergency Medicine, Virginia Commonwealth University Health System, Richmond, VA. 6Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA. 7Department of Anesthesia Critical Care, Division of Critical Care, Beth Israel Deaconess Medical Center, Boston, - - 2014
Rate of lactate change is associated with in-hospital mortality in post-cardiac arrest patients. This association has not been validated in a prospective multicenter study. The objective of the current study was to determine the association between percent lactate change and outcomes in post-cardiac arrest patients. Four-center prospective observational study conducted ...
Dal Molin Alberto A 1 School of Nursing, Biella Hospital, Avogadro University, Biella - - - 2014
The aim of this systematic review was to assess the efficacy of heparin flushing in the lock of central venous catheters. We searched MEDLINE and CINAHL databases. Eligible studies were randomized controlled trials evaluating the use of heparin versus normal saline or other solution in the flushing of central catheter ...
Eftekhari Kian K Scheie Eye Institute, Department of Ophthalmology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, - - 2014
The aim of this study is to determine if oral fluoroquinolone exposure is associated with an increased hazard for having a retinal tear or detachment. A retrospective cohort study was performed using individuals who met inclusion criteria from The Health Improvement Network database. Cohorts were created for individuals who had ...
Lin Po-Yen PY Department of Dentistry, School of Dentistry, National Yang-Ming University, Taipei, - - 2014
Pulpotomy is a common procedure to treat asymptomatic reversible pulpitis in primary molars. The aim of this study is to undertake a systematic review and a network meta-analysis to compare the clinical and radiographic outcomes of different pulpotomy procedures in primary molars. Data: Three authors performed data extraction independently and ...
Bonnin Philippe P Sorbonne-Paris-Cité, AP-HP, Lariboisiere hospital, Department of Clinical-Physiology - Functional-Investigations, Paris-Diderot University, Paris, France; Sorbonne-Paris-Cité, INSERM, U965, Paris-Diderot University, Lariboisiere Hospital, Paris, - - 2014
Determine the effect of repeated intravitreal injections of ranibizumab (0.5 mg; 0.05 ml) on retrobulbar blood flow velocities (BFVs) using ultrasound imaging quantification in twenty patients with exudative age-related macular degeneration treated for 6 months. Visual acuity (ETDRS), central macular thickness (OCT), peak-systolic, end-diastolic and mean-BFVs in central retinal (CRA), temporal posterior ciliary ...
Kagan Richard J RJ From the *Shriners Hospitals for Children-Cincinnati, Ohio; and the †Department of Surgery, University of Cincinnati College of Medicine, - - 2014
Existing practice guidelines designed to minimize invasive catheter infections and insertion-related complications in general intensive care unit patients are difficult to apply to the burn population. Burn-specific guidelines for optimal frequency for catheter exchange do not exist, and great variation exists among institutions. Previously, the practice was to follow a ...
Lesar Christopher J CJ Department of Surgery, University of Tennessee College of Medicine, Chattanooga, Chattanooga, TN. Electronic address: - - 2014
Carotid endarterectomy (CEA) is often completed with general anesthesia and routine shunting; however, shunting is only required in a small group of at-risk patients to maintain adequate cerebral perfusion. Selective shunting during CEA is performed to normalize cerebral hemodynamics for patients determined to be at risk. Eversion CEA with selective ...
Huang Qingling Q Department of Radiology, Nanjing Brain Hospital Affiliated to Nanjing Medical University, Nanjing, - - 2014
Brain tumor patients often associated with losses of the small-world configuration and neurocognitive functions before operations. However, few studies were performed on the impairments of frontal lobe low-grade gliomas (LGG) after tumor resection using small-world network features. To detect differences in the whole brain topology among LGG patients before and ...
Horie Nobutaka N Department of Neurosurgery, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki 852-8501, - - 2014
Volume management is critical for assessment of cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH). This multicenter prospective cohort study compared the impact of surgical clipping versus endovascular coiling on postoperative hemodynamics and pulmonary edema in patients with SAH. Hemodynamic parameters were measured for 14 days using a transpulmonary thermodilution system. ...
Beudel Martijn M Department of Neurology and Clinical Neurophysiology, Medisch Spectrum Twente , Enschede , Netherlands ; Department of Neurology, University Medical Centre Groningen , Groningen , - - 2014
Post-anoxic encephalopathy (PAE) has a heterogenous outcome which is difficult to predict. At present, it is possible to predict poor outcome using somatosensory evoked potentials in only a minority of the patients at an early stage. In addition, it remains difficult to predict good outcome at an early stage. Network ...
Jacomella Vincenzo V Clinic for Angiology, University Hospital Zurich, Zurich, - - 2014
In patients suffering from symptomatic peripheral artery disease (PAD), percutaneous revascularization is the treatment of choice. However, restenosis may occur in 10 to 60% in the first year depending on a variety of factors. Small dense low density lipoprotein (sdLDL) particles are associated with an increased risk for cardiovascular events, ...
Tsuchiya Tomonori T Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan. - - 2013
The issue on timing and number of bile sampling for exfoliative bile cytology is still unsettled. A total of 100 patients with cholangiocarcinoma undergoing resection after external biliary drainage were randomized into two groups: a 2-day group where bile was sampled five times per day for 2 days; and a ...
Adams Katie K Department of Colorectal Surgery, King's College Hospital, Denmark Hill, London, SE5 9RS, UK, - - 2013
Anastomotic leaks greatly increase both morbidity and mortality amongst colorectal patients. Earlier detection of leaks leads to improved patient outcomes; however, diagnosis often proves difficult due to heterogeneous presentation and varied differential diagnosis. The purpose of the study was to create an artificial neural network (ANN) capable of accurately identifying ...
Finkelstein Renato R Infectious Diseases Unit, Technion, Israel Institute of Technology, Haifa, - - 2014
Objective. To evaluate the effect of an optimized policy for antibiotic prophylaxis on surgical site infection (SSI) rates in cardiac surgery. Design. Prospective cohort study. Setting. Tertiary medical center in Israel. Methods. SSIs were recorded during a 10-year study period and ascertained through routine surveillance using the National Healthcare Safety Network (NHSN) methodology. Multivariable ...
Fitz-Gerald Alison Louise - - 2013
To compare operating time, intraoperative blood loss, postoperative analgesia, and length of hospital stay using ultrasonic shears vs traditional suture ligature in vaginal hysterectomy. Randomized controlled trial (Canadian Task Force classification I). Gynecology units within a single health network, university hospital. Forty women requiring vaginal hysterectomy because of benign disease. ...
Solaymani-Dodaran Masoud - - 2013
Iranian Registry of Clinical Trials (IRCT) commenced its activities as a member of WHO registry network on fourth of December 2008. We explored the progress it has made within its first four years both in terms of quantity of registrations as well as its timeliness. We downloaded all the approved ...
Zhao Jian - - 2013
The transmural biodegradable polycaprolactone/poly(D,L-lactic/glycolic acid) (PCL/PLGA) scaffold is a promising modality for diffuse coronary atherosclerosis cases that are not suitable for bypass grafting. The purpose of this study was to evaluate the long-term performance of the PCL/PLGA scaffold in vivo in the setting of polymer and heparin degradation. After mechanical drilling ...
Nunn Martha E - - 2013
Bayesian network meta-analysis of root coverage procedures: ranking efficacy and identification of best treatment. Buti J, Baccini M, Nieri M, La Marca M, Pini-Prato GP. J Clin Periodontol 2013;40(4):372-86. Martha E. Nunn, DDS, PhD, Takanari Miyamoto, DDS, MSD, PhD PURPOSE/QUESTION: What is the ranking efficacy and identification of the best ...
Lee Joo Yong - - 2013
Abstract Objective: To conduct a meta-analysis of studies that compared transperitoneal (TP) and extraperitoneal (EP) robot-assisted radical prostatectomy (RARP). Materials and Methods: PubMed, the Cochrane Library, and EMBASE online databases were searched for studies released prior to June 2012. References were manually reviewed, and two researchers independently extracted the data. ...
Kulkarni Abhaya V - - 2013
Object The Hydrocephalus Clinical Research Network (HCRN), which comprises 7 pediatric neurosurgical centers in North America, provides a unique multicenter assessment of the current outcomes of CSF shunting in nonselected patients. The authors present the initial results for this cohort and compare them with results from prospective multicenter trials performed ...
Tang Peter P Allegheny Health Network, Pittsburgh, - - 2013
Background Proximal row carpectomy (PRC) is a useful treatment option for wrist arthritis, but the operation is contraindicated when there is arthritis of the capitate head. We describe a technique that involves resurfacing of a capitate that has focal chondrosis, using an osteochondral graft harvested from the resected carpal bones. ...
Kim Romina - - 2013
Abstract Purpose . To describe effective retention strategies in a clinical trial with a high risk, low-income, and vulnerable patient population with serious mental illness. Design . Follow-up assessments were conducted for a randomized clinical tobacco treatment trial at 3, 6, and 12 months postbaseline. Initial follow-up rates of <40% ...
Landoni G - - 2013
/st>Many studies have compared desflurane, isoflurane, sevoflurane, total i.v. anaesthesia (TIVA), or all in cardiac surgery to assess their effects on patient survival. /st>We performed standard pairwise and Bayesian network meta-analyses; the latter allows indirect assessments if any of the anaesthetic agents were not compared in head-to-head trials. Pertinent studies ...
García-Vázquez Elisa - - 2013
Background: Coagulase-negative staphylococci (CoNS) are common contaminants in blood cultures (BC). A prospective study of patients with ≥ 2 blood culture sets and at least 1 positive CoNS BC was performed to develop an algorithm to assist in determining the clinical significance of CoNS bacteraemia. Methods: A single reviewer examined ...
Metrot Julien - - 2013
To investigate the time-related changes in motor performance of the ipsilesional upper-limb in subacute post-stroke patients by using clinical and kinematic assessments. Observational, longitudinal, prospective, monocentric study. Physical Medicine and Rehabilitation Department PARTICIPANTS: 19 stroke patients (mean age 62.9) were included less than thirty days after a first unilateral ischemic/hemorrhagic ...
Porcaro Antonio B - - 2013
Aim: To investigate the potential of preoperative serum total testosterone (TT) in contributing to the definition of separate prostatectomy Gleason score (pGS) groups of the prostate cancer (PCa) population. Materials and Methods: The data of 220 patients operated on for PCa were retrospectively reviewed. No patient had previously received 5α-reductase ...
Fang Yi - - 2013
Background and objectives: The effective dose of radioiodine ablation for patients with differentiated thyroid cancer (DTC) after thyroidectomy was unclear, so we tried to find out which activity is the best using the methods of direct comparison and network meta-analyses. Methods: Direct comparison and network meta-analyses were conducted by ADDIS ...
Mitchell Stephen A - - 2013
The novel oral anticoagulants (NOACs) apixaban, dabigatran, and rivaroxaban have been recently indicated for stroke prevention in patients with atrial fibrillation (AF) . Due to a lack of direct head-to-head trials comparing the NOACs, the current systematic review and network meta-analysis (NMA) were conducted to assess their relative efficacy and ...
Chatterjee Saurav - - 2013
BACKGROUND: We attempted to evaluate if an oral-only regimen was as effective in preventing postoperative atrial fibrillation (POAF) after cardiac surgery, in comparison to a regimen that included intravenous (IV) administration using a network meta-analysis of available data, and also attempted to assess if preoperative administration at least 1 day ...
Suzuki Mihoko - - 2013
PURPOSE: To investigate changes in fundus autofluorescence (FAF) during 3 years of follow-up in patients with polypoidal choroidal vasculopathy (PCV). DESIGN: Retrospective study. METHODS: We retrospectively reviewed the charts of 48 eyes of 47 patients (35 men, 12 women; mean age, 69.9 ± 7.1 years) with treatment-naïve PCV for whom FAF and indocyanine green ...
Hernández-Díaz Sonia - - 2013
BACKGROUND: Few studies have evaluated the prevention of upper gastrointestinal complications (UGIC; bleeding or perforation) in patients with uncomplicated peptic ulcer (PU). We assessed the effect of proton pump inhibitors (PPI) in a non-randomized setting. To maximize exchangeability of exposed and unexposed groups we restricted the study to patients with ...
Buti Jacopo J Department of Public Health, University of Florence, Florence, Italy. - - 2013
The aim of this work was to conduct a Bayesian network meta-analysis (NM) of randomized controlled trials (RCTs) to establish a ranking in efficacy and the best technique for coronally advanced flap (CAF)-based root coverage procedures. A literature search on PubMed, Cochrane libraries, EMBASE, and hand-searched journals until June 2012 ...
Aslan Belma Işιk - - 2013
Aim: The purpose of this prospective study was to determine the number of contacts in centric occlusion during retention with modified and full-coverage thermoplastic Essix retainers. Methods: This research was based on 36 patients who were randomly assigned to wear either modified (18 patients) or full-coverage (18 patients) Essix retainers. ...
Stanganelli Ignazio - - 2013
Objective: Small- and intermediate-sized congenital nevi (SCN and ICN) undergo periodic clinical monitoring or surgical excision. We analyzed the management of SCN and ICN in the Italian hospital network. Methods: A nationwide survey of a representative sample of centers was conducted. Data were analyzed grouping centers by melanoma incidence into ...
Mori Hirohito - - 2013
The antiseptic effect of gastric irrigation before endoscopic submucosal dissection (ESD) has not yet been reported. The aim of the randomized prospective study is to evaluate the antiseptic effects of gastric irrigation of saline solution before ESD by evaluating bacterial count. This prospective randomized controlled trial included 50 patients diagnosed ...
Rathod Krishnaraj S KS Department of Cardiology, Barts and the London NHS Trust, London, - - 2013
Timely delivery of primary percutaneous coronary intervention (PPCI) is the treatment of choice for ST-segment elevation myocardial infarction (STEMI). Optimum delivery of PPCI requires an integrated network of hospitals, following a multidisciplinary, consultant-led, protocol-driven approach. We investigated whether such a strategy was effective in providing equally effective in-hospital and long-term ...
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