Search Results
Results 1 - 50 of 2866
1 2 3 4 5 6 7 8 9 10 >
Her Ae-Young AY Division of Cardiology, Department of Internal Medicine, School of Medicine, Kangwon National University, Chuncheon, South - - 2014
We sought to investigate the effect of ward-to-cath lab blood pressure (BP) differences on long-term clinical outcomes in patients undergoing percutaneous coronary intervention (PCI) with drug-eluting stent (DES). There are limited data available on the association between PCI with DES and BP differences on long-term clinical outcomes. This study enrolled ...
Bangalore Sripal S New York University School of Medicine, New York, - - 2014
Background: The safety of drug eluting stents (DES) vs. bare metal stents (BMS) in the perioperative setting, a heightened state of inflammation and thrombosis is not well defined. Methods: All adults undergoing NCS within 1 year following percutaneous coronary intervention (PCI) in Massachusetts between April 1, 2004 and September 30, ...
Ieguchi Makoto M Department of Orthopedic Surgery, Yodogawa Christian Hospital, Osaka - - 2014
Extra-articular resection is necessary to obtain a wide margin for primary osteosarcomas invading the knee joint, and the limb is often reconstructed using a prosthesis. Here, outcomes of extra-articular and intra-articular procedures were compared. Between 1999 and 2012, 14 patients with osteosarcoma underwent extra-articular excision (n = 6; ages 23-65 ...
Lund Lars H LH Karolinska Institutet, Department of Medicine, Stockholm, Sweden; Karolinska University Hospital, Department of Cardiology, Stockholm, - - 2014
The prevalence of cardiovascular and non-cardiovascular co-morbidities and their relative importance for outcomes in heart failure with preserved ejection fraction (HFPEF) remain poorly characterized. This study aimed to investigate this. The Karolinska-Rennes (KaRen) Study was a multinational prospective observational study designed to characterize HFPEF. Inclusion required acute HF, defined by ...
Savage Stephanie A SA From the Division of Trauma & Critical Care, University of Tennessee Health Science Center, Memphis, - - 2014
The practice of 1:1 transfusion, administering packed red blood cells (PRBCs) with fresh frozen plasma (FFP), has been associated with improved survival. However, the reported ratios are the result of mathematical averages over 24 hours and do not necessarily represent concurrent administration. Using critical administration thresholds (CAT+) of more than ...
Qian Jie J Department of Cardiology, FuWai Hospital, National Center for Cardiovascular Diseases, Beijing, - - 2014
Aims: To compare stent strut coverage using optical coherence tomography (OCT) at three-month follow-up between a PLGA-polymer with electro-grafting base layer sirolimus-eluting stent (SES) (BuMA) and a PLA-polymer SES (EXCEL). Methods and results: This prospective, single-centre, non-inferiority randomised BuMA-OCT trial enrolled patients with de novo coronary artery lesions, treated with ...
Dattolo Pietro P Nephrology and Dialysis Unit, SM Annunziata Hospital, Florence, Italy, - - 2014
The optimal timing of dialysis initiation is still unclear. We aimed to ascertain whether a strict clinical follow-up can postpone need for dialysis in chronic kidney disease (CKD) stage 5 patients. We reviewed records of all consecutive adult patients attending our conservative CKD stage 5 outpatient clinic from 2001 to ...
Lee Melissa G Y MG Department of Cardiac Surgery, The Royal Children's Hospital, Melbourne, Victoria, Australia; Department of Pediatrics, University of Melbourne, Melbourne, Victoria, Australia; Murdoch Childrens Research Institute, Melbourne, Victoria, - - 2014
The purpose of this study was to determine the rate of reinterventions from birth to adulthood after end-to-side anastomosis technique for interrupted and hypoplastic aortic arches. Multicenter data have shown that more than half of patients require arch reintervention in the 2 decades after repair. The follow-up of 170 consecutive ...
Conrad Mark F MF Division of Vascular and Endovascular Surgery, Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Mass. Electronic address: - - 2014
Although level 1 evidence supports carotid endarterectomy (CEA) for stroke prevention in patients with asymptomatic severe carotid artery stenosis (ASCAS; >70%), medical therapy alone has been promulgated by some as equally effective. The goal of this study was to determine the natural history of medically treated patients with ASCAS. Patients ...
Klintmalm G B GB Annette C. and Harold C. Simmons Transplant Institute, Baylor University Medical Center, Dallas, - - 2014
This exploratory phase II study evaluated the safety and efficacy of belatacept in de novo adult liver transplant recipients. Patients were randomized (N = 260) to one of the following immunosuppressive regimens: (i) basiliximab + belatacept high dose [HD] + mycophenolate mofetil (MMF), (ii) belatacept HD + MMF, (iii) belatacept low dose [LD] + MMF, (iv) tacrolimus + MMF, or (v) tacrolimus ...
Généreux Philippe P Columbia University Medical Center and Cardiovascular Research Foundation, New York, NY, - - 2014
Aims: We sought to describe the incidence, predictors, and impact of adverse neurological events (NE) in a non-ST-segment elevation acute coronary syndromes (NSTEACS) population undergoing percutaneous coronary intervention (PCI), coronary artery bypass grafting (CABG), or medical therapy (MT). Methods and results: 13,819 patients with moderate and high-risk NSTEACS were enrolled ...
Svensson Lars G LG Cleveland Clinic, Cleveland, Ohio; PARTNER Publication Office, New York, New York, and Cleveland, Ohio. Electronic address: - - 2014
Patients with severe aortic stenosis (AS) who were deemed too high risk or inoperable for conventional aortic valve replacement (AVR) in the PARTNER (Placement of Aortic Transcatheter Valves) trial were randomized to transcatheter aortic valve replacement (TAVR) versus AVR (PARTNER-A arm) or standard therapy (PARTNER-B arm). This study compared when ...
Wilcox Robert R Faculty of Medicine & Health Sciences, Cardiovascular Medicine, Nottingham, - - 2014
Abstract Background In TRITON-TIMI 38, patients with acute coronary syndromes were treated with prasugrel or clopidogrel, with acetylsalicylic acid, for a median of 14.5 (maximum of 15) months. Based on this trial, the EU label for prasugrel recommends treatment for up to 12 months and excludes patients with prior stroke/TIA. ...
Bhama Prabhat K PK Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Boston, - - 2014
Background Free tissue transfer is a reliable method for reconstruction of head and neck defects. With the growing number of octogenarians in the population, it is important to understand how these patients respond to these procedures. Methods Through a retrospective chart review of patients who underwent a free-flap reconstruction from 2000 to ...
Heeley Emma L EL The George Institute for Global Health, Sydney Medical School, University of Sydney, Sydney, - - 2014
Antihypertensive drugs are useful in the prevention of stroke; however, much debate surrounds which class of agent provides the most benefit post-stroke. The aim of this study was to examine the impact of different classes of antihypertensive agent on stroke outcome using data from the ChinaQUEST study, a prospective, hospital-based ...
Liu Xue-Hua XH Department of Intensive Care Unit, TianJin People's Hospital , TianJin, China - - 2014
Aim: The aim of this study was to identify whether mannose-binding lectin (MBL) and C-reactive protein (CRP) may be used as clinical biomarkers for predicting outcome of community-acquired pneumonia (CAP) by tracking serum MBL and CRP level changes during a time course. Methods: One hundred four patients with CAP and ...
Shi Guocheng G Department of Cardiothoracic Surgery, Shanghai Children's Medical Center, Heart Center, Shanghai Jiaotong University School of Medicine, Shanghai, - - 2014
Interrupted aortic arch (IAA) is a complicated congenital heart disease requiring an individualized management strategy. We reported the results for surgical repair of IAA with associated anomalies. This was a retrospective review of 119 patients undergoing one-stage biventricular repair of IAA with associated lesions at the median age of 18 ...
Fontana Robert J RJ Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, MI, - - 2014
The long-term clinical outcomes in initial survivors with acute liver failure (ALF) are not well known. The aim of the current study is to provide an overview of the 2 year clinical outcomes amongst initial survivors and liver transplant (LT) recipients that were alive 3 weeks after enrollment in the ...
Hidaka Nobuhiro - - 2014
Abstract Objective: We aimed to investigate the clinical characteristics and postnatal outcomes of fetuses with congenital diaphragmatic hernia (CDH) and additional anomalies. Materials and methods: We reviewed the charts of fetuses with CDH managed between 2005 and 2013. Patients were divided into complex and isolated groups based on the presence ...
Moonesinghe S R SR UCL/UCLH Surgical Outcomes Research Centre, Department of Anaesthetics, University College Hospital, London NW1 2BU, UK UCL Centre for Anaesthesia, University College Hospital, London NW1 2BU, UK National Institute for Academic Anaesthesia's Health Services Research Centre, Royal College of Anaesthetists, 35 Red Lion Square, London WC1R 4SG, UK - - 2014
Previous studies have suggested that there may be long-term harm associated with postoperative complications. Uncertainty exists however, because of the need for risk adjustment and inconsistent definitions of postoperative morbidity. We did a longitudinal observational cohort study of patients undergoing major surgery. Case-mix adjustment was applied and morbidity was recorded ...
Lee Cheol Whan CW Department of Medicine, Asan Medical Center, University of Ulsan, Seoul, - - 2014
We investigated the temporal patterns of drug-eluting stents (DES) failure and its relationship with clinical outcomes in patients with DES failure. Time to DES failure is widely variable, but little information is available on the temporal patterns of DES failure and its impact on clinical outcomes. The angiographic patterns of ...
Wu Cynthia C Department of Medicine, University of Alberta, Edmonton, Alberta, Canada. Electronic address: - - 2014
The frequency and case fatality of venous thromboembolism (VTE) and major bleeding during the initial 3months of therapy in those treated for symptomatic VTE with either direct oral anticoagulants (DOACs) or vitamin K antagonists (VKA) are important clinically relevant outcomes. We sought to measure it during the initial months of ...
Dvir Danny D St Paul's Hospital, Vancouver, British Columbia, - - 2014
Owing to a considerable shift toward bioprosthesis implantation rather than mechanical valves, it is expected that patients will increasingly present with degenerated bioprostheses in the next few years. Transcatheter aortic valve-in-valve implantation is a less invasive approach for patients with structural valve deterioration; however, a comprehensive evaluation of survival after ...
Kuwaki Hiroshi H Second Department of Internal Medicine, University of Occupational and Environmental Health, School of Medicine, Kitakyushu, - - 2014
This study sought to examine left atrial (LA) mechanics and the prognostic impact of patients with echocardiographic findings of E/A ratio ≤0.75, deceleration time (DcT) of mitral E-wave >140 ms, but E/ε' ≥10. Traditional diastolic dysfunction (DD) grading system could not classify every patient into a specific group. We considered the group ...
Callaghan John J JJ Department of Orthopaedic Surgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, 01029 JPP, Iowa City, IA, 52242, USA, - - 2014
Long-term evaluation of knee arthroplasty should provide relevant information concerning the durability and performance of the implant and the procedure. Because most arthroplasties are performed in older patients, most long-term followup studies have been performed in elderly cohorts and have had low patient survivorship to final followup; the degree to ...
Speziale Francesco F Vascular and Endovascular Surgery Unit, "Sapienza" University of - - 2014
Endovascular aneurysm repair (EVAR) has fast become the therapeutic strategy of choice for abdominal aortic aneurysms (AAA). Nowadays, the most important limit to the effectiveness of this technique is represented by complex anatomical situations, especially regarding the morphology of the proximal sealing zone. The aim of the present study was ...
Hunt Linda P LP Musculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Bristol, - - 2014
Understanding the risk factors for early death after knee replacement could help to reduce the risk of mortality after this procedure. We assessed secular trends in death within 45 days of knee replacement for osteoarthritis in England and Wales, with the aim of investigating whether any change that we recorded ...
Murakami Hironori H Division of Cardiology, Cardiovascular Center, Teine Keijinkai Hospital, Sapporo, Japan. Electronic address: - - 2014
The prevalence of severe sclerotic aortic stenosis (ScAS) in those at least ≧80 years old has been increasing in Japan; however, the prognosis of these Japanese patients without surgical treatment has not been reported. Ninety consecutive patients with medically treated severe ScAS were prospectively studied. To assess further event-free survival ...
Larsen Jacob M JM Department of Cardiology and Center for Cardiovascular Research, Aalborg University Hospital. Electronic address: - - 2014
Recalled St Jude Medical Riata defibrillator leads are prone to insulation failures with externalized conductors (EC). Longitudinal studies are needed to guide lead management. To describe the dynamic nature of EC and the association with electrical abnormalities and lead extraction outcomes. A nationwide cohort established in 2012 of 295 patients ...
Feng Yunlin Y Division of Nephrology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu 610072, - - 2014
Cystatin-C (CysC) has been demonstrated as a sensitive and reliable biomarker to predict the onset of acute kidney injury (AKI). However, few studies concerned about the relationship between CysC and the outcomes of AKI. To determine whether CysC elevation prior to definite diagnosis of AKI is related to higher prevalence ...
Ogihara Toshio T aMorinomiya University of Medical Sciences, Osaka bKeio University, Tokyo cOsaka University Graduate School of Medicine, Osaka dSapporo Medical University, Hokkaido eDokkyo Medical University fShin-Oyama City Hospital, Tochigi gTohoku University Graduate School of Medicine, Miyagi hEhime University Graduate School of Medicine, Ehime iKurume University School of Medicine, Fukuoka jUniversity of the Ryukyus School of Medicine, Okinawa kSaitama Medical University, Saitama lAsahi Rousai Hospital, Aichi mYokohama City University Graduate School of Medicine, Kanagawa nSapporo Nishimaruyama Hospital, Hokkaido oTokyo Medical University, Tokyo pKawasaki Medical School, Okayama qKanazawa University Hospital, Ishikawa, - - 2014
The aim of the present study was to compare the cardiovascular effects of olmesartan, an angiotensin II receptor blocker, combined with a calcium channel blocker (CCB) or a diuretic, in a prospective, randomized, open-label, blinded endpoint trial. Japanese hypertensive patients aged at least 65 to less than 85 years with ...
Ugare G U GU Department of Surgery, University of Calabar Teaching Hospital, Calabar, - - 2014
Aims and objectives: The objective of the following study is to analyze the trauma type (causes), injury pattern and factors that may have contributed to death within 72 h of admission into our emergency department (E.D). Materials and Methods: An 18 month prospective observational study, done from April 2009 to ...
Spargias Konstantinos K Departments of Transcatheter Heart Valves, Hygeia Hospital, Athens, - - 2014
Transcatheter aortic valve replacement (TAVR) is now an established treatment for certain patients with severe aortic valve stenosis (AS). However, as the number of patients screened for TAVR increases, many are found to have absolutely no option for peripheral artery access. Transaortic valve replacement (TAoVR) has been proposed as a ...
Hahn Rebecca T RT Columbia University Medical Center/New York Presbyterian Hospital, New York, New York. Electronic address: - - 2014
This study sought to characterize the patients receiving post-implantation balloon dilation (PD) following transcatheter aortic valve replacement (TAVR) and evaluate procedural outcomes in the PARTNER (Placement of Aortic Transcatheter Valve) I trial. Following TAVR, PD has been used to treat paravalvular regurgitation. The PARTNER I trial cohort A (n = 304) and ...
Serra-Grima Ricard R Department of Cardiology, Hospital de la Santa Creu i Sant Pau, IIb-Sant Pau, Universitat Autónoma de Barcelona, Barcelona, - - 2014
Analyze the prevalence, clinical characteristics, and long-term outcome of early repolarization pattern (ERP) in elite athletes during professional activity and after retirement. ERP is considered a benign variant of the ECG, more frequent in athletes. However, prospective studies suggested that ERP is associated with an increased risk of sudden cardiac ...
Fokkema Margriet M *Department of Vascular Surgery, University Medical Center Utrecht, The Netherlands †Department of Vascular and Endovascular Surgery, Beth Israel Medical Center, Boston, MA ‡Experimental Cardiology Laboratory, University Medical Center Utrecht, Utrecht, the Netherlands §Interuniversity Cardiology Institute of the Netherlands, Utrecht, the Netherlands; and ¶Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The - - 2014
To study perioperative results and restenosis during follow-up of carotid artery stenting (CAS) versus carotid endarterectomy (CEA) for restenosis after prior ipsilateral CEA in an individual patient data (IPD) meta-analysis. The optimal treatment strategy for patients with restenosis after CEA remains unknown. A comprehensive search of electronic databases (Medline, Embase) ...
Nassar George M GM Dialysis Access Management Centers, Nephrology Dialysis and Transplantation Associates, The Kidney Institute & Houston Methodist Hospital, Weill Cornell University, Houston, - - 2014
Arteriovenous grafts (AVGs) suffer from high thrombosis rates. It is not known whether placement of stent grafts at the venous anastomosis (VA) of thrombosed AVGs would impact future thrombosis. This is a retrospective study evaluating a group of AVGs that underwent endovascular thrombectomy with placement of a stent graft at ...
Mazilu L L "OVIDIUS" University of Constanta, Faculty of General Medicine, CONSTANTA, - - 2014
Secondary prevention of thromboembolic disease in cancer patients with oral anticoagulants is a challenging issue, due to the particular liver biology in this high-risk category of subjects. To compare novel oral anticoagulant dabigatran vs acenocumarol administered in patients with malignant disease and deep vein thrombosis. We randomized 46 patients with ...
Dillier Roger R German Heart Center Munich, Technical University, Munich, Germany - - 2014
-This study aimed to evaluate the safety of continuous periprocedural rivaroxaban administration during left atrial RFA in comparison with uninterrupted oral vitamin K antagonist (VKA) administration. Data about the use of rivaroxaban in the setting of left atrial radiofrequency catheter ablation (RFA) procedures are lacking. -The study cohort included 544 ...
Siempos Ilias I II Department of Medicine, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; First Department of Critical Care Medicine and Pulmonary Services, Evangelismos Hospital, University of Athens Medical School, Athens, Greece; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medical College, New York, NY, USA. Electronic address: - - 2014
Delay of tracheostomy for roughly 2 weeks after translaryngeal intubation of critically ill patients is the presently recommended practice and is supported by findings from large trials. However, these trials were suboptimally powered to detect small but clinically important effects on mortality. We aimed to assess the mortality benefit of ...
Boulware David R DR From the University of Minnesota, Minneapolis (D.R.B., D.B.M., M.A.R., K.H.H., D.A.W., R.R., J.R., M.W.L., K.N., T.L.B., P.R.B.); the Infectious Disease Institute (D.B.M., A.M., H.W.N., D.A.W., R.R., J.R., M.W.L., A.K., Y.C.M.) and School of Medicine, College of Health Sciences (D.B.M.), Makerere University, Kampala, and Mbarara University of Science and Technology, Mbarara (C.M., K.T.) - both in Uganda; the University of Cape Town, Cape Town, South Africa (C.S., F.T., G.M.); Johns Hopkins School of Medicine, Baltimore (Y.C.M.); the Mucosal and Vaccine Research Program Colorado (MAVRC), University of Colorado Denver, Aurora, and Denver Veterans Affairs Medical Center, Denver (E.N.J.); and Imperial College London, London - - 2014
Cryptococcal meningitis accounts for 20 to 25% of acquired immunodeficiency syndrome-related deaths in Africa. Antiretroviral therapy (ART) is essential for survival; however, the question of when ART should be initiated after diagnosis of cryptococcal meningitis remains unanswered. We assessed survival at 26 weeks among 177 human immunodeficiency virus-infected adults in ...
Bisdas Theodosios T Department of Vascular Surgery, St. Franziskus Hospital and University Clinic of Muenster, Muenster, Germany. Electronic address: - - 2014
Several studies have confirmed the excellent early performance of the Endurant (Medtronic Endovascular, Santa Rosa, Calif) endoprosthesis to treat abdominal aortic aneurysms (AAAs). However, data about the long-term durability of the device are still lacking. We conducted this prospective two-center single-arm study to assess the late outcomes of the endograft ...
van Laar Jacob M JM Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United - - 2014
High-dose immunosuppressive therapy and autologous hematopoietic stem cell transplantation (HSCT) have shown efficacy in systemic sclerosis in phase 1 and small phase 2 trials. To compare efficacy and safety of HSCT vs 12 successive monthly intravenous pulses of cyclophosphamide. The Autologous Stem Cell Transplantation International Scleroderma (ASTIS) trial, a phase ...
Brunkwall J J Department of Vascular and Endovascular Surgery, University Clinics, University of Cologne, Cologne, Germany. Electronic address: - - 2014
Uncomplicated acute type B aortic dissection (AD) treated conservatively has a 10% 30-day mortality and up to 25% need intervention within 4 years. In complicated AD, stent grafts have been encouraging. The aim of the present prospective randomised trial was to compare best medical treatment (BMT) with BMT and Gore ...
Sánchez-Recalde Angel A Servicio de Cardiología, Hospital Universitario La Paz, Madrid, Spain. Electronic address: - - 2014
Percutaneous closure of paravalvular leakage is an alternative to surgery in high-risk patients, but its use has been limited by a lack of specific devices. More appropriate devices-like the Amplatzer Vascular Plug III-have recently been developed, but information about their efficacy and safety is still scarce. The objective of the ...
Sánchez-Recalde Angel A Servicio de Cardiología, Hospital Universitario La Paz, Madrid, España. Electronic address: - - 2014
Percutaneous closure of paravalvular leakage is an alternative to surgery in high-risk patients, but its use has been limited by a lack of specific devices. More appropriate devices-like the Amplatzer Vascular Plug III-have recently been developed, but information about their efficacy and safety is still scarce. The objective of the ...
Lee Hsin-Fu HF Cardiovascular Division, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou, Taoyuan, - - 2014
Dilated inferior vena cava (IVC) is prevalent among patients with heart failure (HF), but whether its presence predicts worsening renal function (WRF) or adverse outcomes is unclear. This cohort study analyzed patients with left ventricular ejection fraction <40 % and repeated hospitalizations (≥2 times) for HF between August 2009 and August ...
Christersson Christina C Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, - - 2014
D-dimer is related to adverse outcome in arterial and venous thromboembolic diseases. To evaluate the predictive value of D-dimer for stroke, other cardiovascular event and bleedings, in patients with atrial fibrillation (AF) treated with oral anticoagulation with apixaban or warfarin; and to evaluate the relationship between the D-dimer levels at ...
Ohno Yohei Y Department of Cardiology, Ferrarotto Hospital, University of Catania, Via Citelli 29, Catania 95124, Italy Department of Cardiology, University of Tokai School of Medicine, Isehara, - - 2014
The aim of this study was to evaluate the association of baseline tricuspid regurgitation (TR) on the outcomes after percutaneous mitral valve repair (PMVR) with the MitraClip system. Data from 146 consecutive patients with functional mitral regurgitation (MR) were obtained. Two different groups, dichotomized according to the degree of pre-procedural ...
Hwang Ho Young HY Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul, Republic of - - 2014
Previous studies have compared the outcomes of mitral annuloplasty with those of mitral valve replacement in patients with functional mitral regurgitation. However, data comparing the results of tricuspid annuloplasty (TAP) with those of tricuspid valve replacement (TVR) in patients with functional tricuspid regurgitation (FTR) have been scarce. We evaluated whether ...
1 2 3 4 5 6 7 8 9 10 >