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Ascheim Deborah D DD From the Icahn School of Medicine at Mount Sinai, New York, NY (D.D.A., A.C.G., M.K.P., J.L., E.B., E.A.R.); Montefiore-Einstein Heart Center, Bronx, NY (D.G.); University of Texas, Houston (L.A.M.); Cleveland Clinic Foundation, Cleveland, OH (N.S., S.L.); University of Florida, Gainesville (C.T.K., A.S.); National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (N.O.J., W.C.T.-P., M.A.M.); Mesoblast Inc, New York, NY (D.S.); Texas Heart Institute, Houston (D.A.T.); University of Pennsylvania, Philadelphia (J.E.R.); Duke University, Durham, NC (C.M., J.G.R.); Baylor Health Care System, Dallas, TX (T.D., E.E.); Minneapolis Heart Institute Foundation, Minneapolis, MN (B.S., D.F.); Mayo Clinic, Rochester, MN (R.S.); Brigham and Women's Hospital, Boston, MA (P.T.O.); Columbia University Medical Center, New York, NY (Y.N.); and Stanford University, Stanford, CA (Y.J.W.). - - 2014
Allogeneic mesenchymal precursor cells (MPCs) injected during left ventricular assist device (LVAD) implantation may contribute to myocardial recovery. This trial explores the safety and efficacy of this strategy. In this multicenter, double-blind, sham-procedure controlled trial, 30 patients were randomized (2:1) to intramyocardial injection of 25 million MPCs or medium during ...
Lio Antonio A Department of Adult Cardiac Surgery, Fondazione Toscana G. Monasterio, Massa, - - 2014
Mitral valve (MV) surgery for ischaemic mitral regurgitation (IMR) in patients with depressed left ventricular ejection fraction (LVEF) is associated with poor outcomes. The optimal surgical strategy for IMR in these patients remains controversial. The objective of this study was to compare the early mortality and mid-term survival of MV ...
De Bonis Michele M Department of Cardiac Surgery, San Raffaele Scientific Institute, Milan, Italy. Electronic address: - - 2014
To assess the very long-term clinical and echocardiographic results of the edge-to-edge repair for mitral regurgitation (MR) due to isolated prolapse or flail of the anterior leaflet. From 1991 to 2004, 139 patients (age, 54 ± 14.4 years; left ventricular ejection fraction 56% ± 7.8%, New York Heart Association class ...
Roberts S E SE College of Medicine, Swansea University, Swansea, - - 2014
BackgroundThe British merchant fleet has expanded in recent years but it is not known whether this expansion has led to proportionate changes in mortality.AimsTo investigate mortality from accidents and injuries in British merchant shipping, to determine whether this has increased in recent years, to compare fatal accident rates across British ...
Yoo Jae Suk JS Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of - - 2014
Background: The clinical benefit of concomitant atrial fibrillation (AF) ablation at the time of aortic valve replacement (AVR) is uncertain. Methods and Results: A total of 124 patients with AF who underwent AVR with (n=50) or without (n=74) a concomitant maze procedure, between 2000 and 2011, were evaluated. There were no significant ...
Hiraoka Arudo A Department of Cardiovascular Surgery, The Sakakibara Heart Institute of Okayama, Okayama, Japan. Electronic address: - - 2014
Right axillary artery (RAxA) perfusion was introduced for selective antegrade cerebral perfusion in total aortic arch repair to prevent cerebral embolism derived from arterial cannulation. However, the strategic benefits and long-term results regarding the cannulation site remain controversial. We retrospectively compared the outcomes between propensity score-matched patients with and without ...
Iwamoto Yumiko Y Department of Cardiology, Hiroshima Prefectural Hospital, Hiroshima, Japan; Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan. Electronic address: - - 2014
We assessed the causes of death and efficacy of permanent inferior vena cava (IVC) filters for preventing new pulmonary embolisms (PE) in Japanese deep vein thrombosis (DVT) patients with or without PE. We studied the clinical outcomes during the follow-up period of 1 day to 9 years (median: 18 months; ...
De Luca Giuseppe G Division of Cardiology, Ospedale "Maggiore Della Carità", Eastern Piedmont University, C.so Mazzini, 18, 24100, Novara, Italy, - - 2014
Large interests have been focused on the role of drug-eluting stents in the setting of ST-segment elevation myocardial infarction (STEMI) and concerns have emerged regarding an higher risk of stent thrombosis. Aim of the current study was to perform a meta-analysis using individual patient data to evaluate the long-term safety ...
Focà Emanuele - - 2014
Aim of our study is to investigate the clinical and immunological outcomes according to first-line HAART adherence in a large cohort of HIV-infected patients in Burkina Faso. A retrospective study was conducted between 2001 and 2009 among patients from two urban medical centers [St. Camille Medical Center (CMSC) and "Pietro ...
Handa Nobuhiro N Affiliations of the National Hospital Organization Network Study Group for Abdominal Aortic Aneurysm in Japan are listed as in the - - 2014
Background: The objective of the present study was to assess the hypothesis that the introduction of endovascular aneurysm repair (EVAR) into Japan has expanded the indication of abdominal aortic aneurysm (AAA) repair without increasing surgical mortality. Methods and Results: From 10 national hospitals, we registered a total of 2,154 consecutive patients (Open ...
Dell' Anna A A Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles (ULB), Brussels, Belgium - - - 2014
Implementation of treatments able to improve survival and neurological recovery of cardiac arrest (CA) survivors is a major clinical challenge. More than ten years ago, two pivotal trials showed that application of therapeutic hypothermia (TH, 32-34° C) to patients resuscitated from an out-of-hospital CA (OHCA) with an initial shockable rhythm ...
Kim Joon Bum JB Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of - - 2014
To compare long-term survival after off-pump and on-pump coronary artery bypass grafting (CABG) BACKGROUND: Although several large-scale clinical trials have compared the surgical outcomes between off-pump and on-pump CABG, the long-term survival has not been compared between the two surgical strategies in a reasonably sized cohort. We evaluated long-term survival ...
Caironi Pietro P From Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda-Ospedale Maggiore Policlinico, Università degli Studi di Milano (P.C., G.I., L.G.), Dipartimento di Anestesia, Rianimazione e Terapia del Dolore, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico (P.C., L.C., L.G.), IRCCS-Istituto di Ricerche Farmacologiche Mario Negri (S.M., R.L.), Dipartimento di Scienze della Salute, Università degli Studi di Milano Bicocca (R.F., A.P.), and Dipartimento di Emergenza-Urgenza, Azienda Ospedaliera S. Paolo-Polo Universitario (G.I.), Milan, Consorzio Mario Negri Sud, Santa Maria Imbaro (G.T., M.R., C.F.), Anestesiologia e Rianimazione, Dipartimento Emergenza-Urgenza, Chirurgia Generale e dei Trapianti, Policlinico Universitario S. Orsola Malpighi, Bologna (S.F.), Dipartimento di Emergenza-Urgenza, Azienda Ospedaliera S. Gerardo, Monza (G.G.), Policlinico Universitario A. Gemelli, Università Cattolica, Rome (M.A.), Ospedale del Mugello-Azienda Sanitaria di Firenze, Florence (V.P.), and Ospedale S. Croce, Moncalieri (G.F.) - all in - - 2014
Although previous studies have suggested the potential advantages of albumin administration in patients with severe sepsis, its efficacy has not been fully established. In this multicenter, open-label trial, we randomly assigned 1818 patients with severe sepsis, in 100 intensive care units (ICUs), to receive either 20% albumin and crystalloid solution ...
Hu Renjie R Heart Center, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, - - 2014
Transventricular valvotomy is a kind of hybrid therapy that is widely used in developing countries where cardiac catheter intervention is limited in neonates. The purpose of this study was to evaluate the surgical outcomes and effectiveness of transventricular valvotomy in neonates with pulmonary atresia and an intact ventricular septum. Between ...
Mizuhashi Satomi S Department of Neurosurgery, National Cerebral and Cardiovascular Center, Suita, - - 2014
Published results for carotid endarterectomy (CEA) in symptomatic and asymptomatic severe carotid stenosis with diabetes mellitus (DM) are contradictory. To evaluate perioperative and long-term results of CEA in patients with DM, we retrospectively analyzed data of patients with or without DM who underwent CEA in our institute. Between January 2005 ...
Sadek Mostafa M The Aortic Wellness Center, Division of Cardiothoracic Surgery, Lenox Hill Hospital, North Shore LIJ Hospital System, New York, New York. Electronic address: - - 2014
Since the advent of endovascular techniques for repair of descending thoracic aortic aneurysms (DTAAs), there has been a relative paucity of current data for open repairs. The purpose of this study was to assess the operative and long-term outcomes in a contemporary series of open repairs of DTAAs. We conducted ...
Wijeysundera Harindra C HC Schulich Heart Centre, Division of Cardiology and Cardiac Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada; Institute for Clinical Evaluative Sciences (ICES), Toronto, Ontario, Canada. Electronic address: - - 2014
There is increasing demand for transcatheter aortic valve replacement (TAVR) as the primary treatment option for patients with severe aortic stenosis who are high-risk surgical candidates or inoperable. We used mathematical simulation models to estimate the hypothetical effectiveness of TAVR with increasing wait times. We applied discrete event modelling, using ...
Fuji Takeshi T Department of Orthopaedic Surgery, Osaka Koseinenkin Hospital, Osaka, Japan. Electronic address: - - 2014
Edoxaban is an oral, direct, once-daily factor Xa inhibitor. This study evaluated the safety and efficacy of edoxaban compared to subcutaneous enoxaparin in Japanese patients undergoing hip fracture surgery. In this multicenter, randomized, open-label, active-comparator, phase 3 trial, 92 patients were randomized 2:1 to receive edoxaban 30mg once daily (n=62) ...
Bevan Priscilla J W PJ Green Lane Cardiothoracic Unit, Auckland City Hospital, New Zealand. Electronic address: - - 2014
Isolated replacement of the tricuspid valve is rare, and the decision to operate is difficult. This study reviews the in-hospital mortality and long-term survival after tricuspid valve replacement in the absence of concomitant left sided valve surgery. It identifies predictors of poor outcome. All patients who underwent tricuspid valve replacement ...
Kalender M M Konya Education and Research Hospital Cardiovascular Surgery Department, Konya, Turkey - - - 2014
Aim: Carotid endarterectomy (CEA) is the treatment of choice for patients with symptomatic and asymptomatic high-grade carotid stenosis. In literature there are papers advocating patch plasty for better results. But there is controversy about which patch material is optimal for use. This study compared rate of neurologic events, and perioperative ...
De Felice Francesco F UO Cardiologia Interventistica, Azienda ASL S. Camillo Forlanini, Circonvallazione Gianicolense n 87, 00152 Roma, Italy. - - 2014
The influence of age on clinical results of primary percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarctions (STEMI) complicated by cardiogenic shock (CS) is poorly investigated. In this study, we evaluated the outcome of 216 consecutive all-comer patients with STEMI and CS undergoing PCI who were divided into ...
Xu Bo B Department of Cardiology, Fu Wai Hospital, National Center for Cardiovascular Diseases, Beijing 100037, - - 2014
In the TARGET I randomized controlled trial, the novel abluminal groove-filled biodegradable polymer sirolimus-eluting stent FIREHAWK proved non-inferior to the everolimus-eluting stent in nine-month in-stent late loss in single de novo coronary lesions. This study was aimed at evaluating clinical safety and effectiveness of FIREHAWK in a moderately complex population ...
Ballaux Ph K E W - - 2014
We performed a retrospective analysis of the maze IV procedures performed in our surgical department for concomitant atrial fibrillation. Preoperative, in-hospital and postoperative follow-up data were collected from 46 consecutive patients who underwent the maze IV operation between April 2006 and December 2010. All electrocardiograms and Holters were reviewed. One ...
Kumbhani Dharam J DJ Division of Cardiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9047, - - 2014
Due to a high burden of systemic cardiovascular events, current guidelines recommend the use of statins in all patients with peripheral artery disease (PAD). We sought to study the impact of statin use on limb prognosis in patients with symptomatic PAD enrolled in the international REACH registry. Statin use was ...
Sandmann W W Hospital Ev. Klinikum Niederrhein, Duisburg, Germany; Department of Vascular Surgery and Kidney Transplantation, Heinrich-Heine-University Hospital, Dusseldorf, Germany. Electronic address: - - 2014
This retrospective study presents the early and late results of pediatric patients who underwent reconstructive surgery for renovascular hypertension (RVH) between 1979 and 2009. From 1979 to 2009 44 patients (male 22; mean age 13 ± 5.2 years, range 1-19 years; early childhood 7 [1-6 years], middle childhood 5 [7-10 years]; adolescents ...
Gold Larry L University of Colorado and SomaLogic; Boulder, CO - - 2014
Many of the authors of these short pieces (who were invited to contribute by Robin Gutell) have already written or spoken about Carl Woese since he died at the end of December 2012. My own thoughts were published in PNAS on February 26, 2013. Still saddened by Carl's death, I ...
Ogura Takeshi T Division of Gastroenterology and Hepatology, Second Department of Internal Medicine, Osaka Medical College, Osaka, - - 2014
Background and study aim: To minimize bile leakage and avoid possible death because of stent migration in endoscopic ultrasound-guided hepaticogastrostomy (EUS-HGS), we have recently combined EUS-HGS with EUS-guided antegrade stenting (EUS-AS) of the biliary obstruction using a novel uncovered metallic stent with a fine-gauge delivery system. In this pilot study, ...
Iyengar Ajay J AJ Department of Cardiac Surgery, Royal Children's Hospital, Melbourne, VIC, - - 2014
To identify factors associated with hospital and long-term outcomes in a binational cohort of extracardiac conduit (ECC) Fontan recipients. All patients who underwent an ECC Fontan procedure from 1997 to 2010 in Australia and New Zealand were identified, and perioperative, follow-up, echocardiographic and reintervention data collected. Risk factors for early ...
Hioki Hirofumi H 1Department of Cardiovascular Medicine, Shinshu University School of Medicine, Matsumoto, - - 2014
Although limb salvage rate has improved in critical limb ischemia (CLI), an improvement in CLI prognosis has been scarcely reported. Multidisciplinary therapy (MT) including revascularization, wound bed preparation, treatment of comorbidity, and education of patients with CLI may improve prognosis. The aim of this study was to investigate the effectiveness ...
Desai Milind Y MY Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio. Electronic address: - - 2014
Thoracic radiation leads to radiation-associated cardiac disease (RACD), associated with substantial cardiac morbidity and mortality, often requiring complex cardiothoracic surgery. In patients with RACD, along with valvular lesions, the aorto-mitral curtain (AMC, junction between base of anterior mitral leaflet and aortic root) thickness is increased on transthoracic echocardiography. We sought ...
von Meijenfeldt G C I GC Department of Vascular Surgery, Erasmus University Medical Centre, Rotterdam, The - - 2014
Endovascular aneurysm repair (EVAR) for ruptured abdominal aortic aneurysm (rAAA) has faced resistance owing to the marginal evidence of benefit over open surgical repair (OSR). This study aims to determine the impact of treatment modality on early mortality after rAAA, and to assess differences in postoperative complications and long-term survival. ...
Baudron C Roubaud CR Pôle de Gérontologie Clinique, CHU Hôpitaux de Bordeaux, F-33000 Bordeaux, - - 2014
SUMMARY To explore the specificities of Escherichia coli bacteraemia in the elderly, the demographic, clinical and bacteriological characteristics and in-hospital mortality rate of 'young' (18-64 years, n = 395), 'old' (65-79 years, n = 372) and 'very old' (⩾80 years, n = 284) adult patients of the multicentre COLIBAFI cohort study were compared. Clinical and bacteriological ...
Murphy Michael O MO The Cardiac Center, The Children's Hospital of Philadelphia, PA, - - 2014
To analyse the incidence and outcomes of early Fontan failure (EFF) in a large contemporary cohort of palliated patients. A retrospective, single-centre study of all patients undergoing primary Fontan from 1 July 1995 to 31 December 2009 was performed. EFF was defined as death, need for extracorporeal membrane oxygenation (ECMO), ...
Mohammadi Siamak S Division of Cardiac Surgery, Quebec Heart and Lung University Hospital, Quebec City, Quebec, - - 2014
The use of bilateral internal thoracic arteries (BITA) has been associated with improved long-term outcomes following coronary artery bypass graft (CABG) surgery. The objective of this study was to evaluate the impact of BITA use on long-term survival among patients with low ejection fraction (EF) undergoing CABG. Between April 1991 ...
Shander Aryeh A Departments of Anesthesiology, Critical Care and Hyperbaric Medicine, Englewood Hospital and Medical Center, Englewood, New - - 2014
Severely anemic patients for whom blood transfusion is not an option provide highly valuable information on risks of anemia and alternative management strategies. This is a retrospective study of consecutive patients at least 18 years old who could not be transfused, had surgery at a patient blood management center between ...
Lee Seung-Jae - - 2014
Cerebrovascular complications (CVCs) frequently occur in patients with acute infective endocarditis (IE). The aim of this study is to describe the clinical findings of CVCs and to evaluate the impact of CVCs on long-term mortality in patients with IE. We retrospectively analyzed 144 patients who fulfilled the modified Duke's criteria ...
Kim Ji-Hyun - - 2014
There are few studies comparing the long-term efficacy and safety of the zotarolimus-eluting stent (ZES) with sirolimus- (SES) and paclitaxel-eluting stents (PES) in the unselected cohorts that were subject to real life clinical practice. Total 2,769 patient who underwent successful percutaneous coronary intervention (PCI) with the three drug-eluting stents (DES) ...
Fang Margaret C MC From the Departments of Medicine (M.C.F., A.S.G.) and Epidemiology & Biostatistics (A.S.G.), University of California, San Francisco; Division of Research (A.S.G., N.K.P., N.U.), Kaiser Permanente of Northern California, Oakland; and Clinical Epidemiology Unit (Y.C., L.H.B., D.E.S.), General Medicine Division, Massachusetts General Hospital, - - 2014
While the short-term impact of atrial fibrillation-related stroke has been well studied, surprisingly little is known about its long-term effect on survival. We followed 13,559 patients with atrial fibrillation for a median of 6 years, identifying ischemic strokes through computerized databases and validating 1,025 events. Stroke severity was determined from ...
Bonaca Marc P MP TIMI Study Group, Brigham and Women's Hospital, Boston, - - 2014
The optimal duration of dual antiplatelet therapy (DAPT) after acute coronary syndrome (ACS) is not known. Factors influencing DAPT duration are not well described. We hypothesized that continued DAPT 12 months beyond ACS would be associated with patient factors such as stent type and that it may be associated with lower ...
Rudd Nancy A NA Section of Cardiology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wis; Herma Heart Center, Children's Hospital of Wisconsin, Milwaukee, Wis. Electronic address: - - 2014
Infants who undergo Norwood stage 1 palliation (S1P) continue with high-risk circulation until stage 2 palliation (S2P). Routine care during the interstage period is associated with 10% to 20% mortality. This report illustrates the sustained reduction of interstage mortality over 10 years associated with use of home monitoring. Daily monitoring of ...
Tomizawa Kenji K Department of Thoracic Surgery, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi, 464-8681, - - 2014
Although 30-day mortality rate is adapted to evaluate perioperative mortality after surgery, whether 90-day mortality rate adequately evaluates perioperative mortality remains unknown. Therefore, we analyzed 30- and 90-day mortality rates after pulmonary resection in patients with primary lung cancer. A total of 2207 pulmonary resections for primary lung cancer performed ...
Chopard Romain R Department of Cardiology, EA3920, University Hospital Besançon, Besançon, France. Electronic address: - - 2014
The purposes of the present study were to determine the impact of chronic obstructive pulmonary disease (COPD) on Valve Academic Research Consortium-defined outcomes in patients undergoing transcatheter aortic valve implantation (TAVI). A total of 3,933 consecutive patients underwent TAVI from January 2010 to December 2011 in 34 centers and were ...
Kalogeropoulos Andreas P AP Division of Cardiology, Emory University, Atlanta, - - 2014
Inflammation is associated with progression of chronic HF. Few data exist on hsCRP levels and their importance in acute HF. In the ASCEND-HF trial biomarker substudy, we measured hsCRP levels at admission (N=794), 48-72h (N=677), and 30 days (N=581) and evaluated their association with outcomes. Levels of hsCRP were considerably ...
Mankikian J J CHRU Tours, Service de Pneumologie, Tours, - - 2014
Amiodarone-induced pulmonary toxicity (APT) is a serious adverse event that can lead to death. The aims of our study are to determine factors associated with mortality and to describe outcome and sequelae of patients with APT. Forty-six patients with APT were divided into two groups according to survival at day ...
Preventza Ourania O Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas; Department of Cardiovascular Surgery, Texas Heart Institute, Houston, Texas. Electronic address: - - 2014
The purpose of our study was to examine when and how to implement the current endoluminal stent graft technology to treat ascending aortic disease. During a 7-year period (March 2006 through July 2013), 7 consecutive patients (median age, 69 years; range, 61.5 to 80.5 years) with multiple comorbidities underwent endoluminal ...
Lindberg-Larsen Martin M Section of Surgical Pathophysiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark, - - 2014
The aim of this nationwide study was to investigate the early morbidity after bilateral simultaneous and staged total knee arthroplasty (TKA) in order to clarify potential benefits of a well-established fast-track regime. The Danish National Patient Registry was searched for all bilateral simultaneous and staged TKA procedures from 2010 to ...
Pan Gaofeng G Department of Thoracic and Cardiovascular Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, P.R. - - 2014
The purpose of this study was to compare the modified single-patch technique with the two-patch technique for infants with complete atrioventricular septal defects (AVSDs). Between December 2001 and October 2011, 98 infants underwent complete AVSD primary repair. Forty-six patients had a modified single-patch technique; 59 patients had a two-patch technique. ...
Humphreys J H JH Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester, Manchester Academic Health Science Centre, United - - 2014
Objectives: To examine mortality rates in UK patients with early rheumatoid arthritis (RA) from 1990-2011, and compare with population trends. Methods: The Norfolk Arthritis Register (NOAR) recruited adults with ≥2 swollen joints for ≥4 weeks: cohort 1 1990-94, cohort 2 1995-99 and cohort 3 2000-04. At baseline, serum RF and ...
Leshnower Bradley G BG Clinical Research Unit, Division of Cardiothoracic Surgery, Joseph B. Whitehead Department of Surgery, Emory University School of Medicine, Atlanta, - - 2014
To examine the clinical outcomes and impact of using moderate hypothermic circulatory arrest (MHCA) and unilateral selective antegrade cerebral perfusion (uSACP) in the setting of total aortic arch replacement (TOTAL). From 2004 to 2012, 733 patients underwent open arch reconstruction with MHCA and SACP. Of these, 145 (20%) underwent TOTAL. ...
López-Alvarez J J Department of Clinical Science and Services, Royal Veterinary College, London, - - 2014
Increased heart rate (HR) and decreased heart rate variability (HRV) are evident in some dogs with degenerative mitral valve disease (DMVD). Evaluation of the factors influencing HR and HRV (assessed by the vasovagal tonus index; VVTI) and their change over time in dogs with DMVD. Client-owned dogs (n = 257) with DMVD ...
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