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Fontana Robert J RJ Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, MI, - - 2014
The long-term clinical outcomes in initial survivors with acute liver failure (ALF) are not well known. The aim of the current study is to provide an overview of the 2 year clinical outcomes amongst initial survivors and liver transplant (LT) recipients that were alive 3 weeks after enrollment in the ...
Hidaka Nobuhiro - - 2014
Abstract Objective: We aimed to investigate the clinical characteristics and postnatal outcomes of fetuses with congenital diaphragmatic hernia (CDH) and additional anomalies. Materials and methods: We reviewed the charts of fetuses with CDH managed between 2005 and 2013. Patients were divided into complex and isolated groups based on the presence ...
Moonesinghe S R SR UCL/UCLH Surgical Outcomes Research Centre, Department of Anaesthetics, University College Hospital, London NW1 2BU, UK UCL Centre for Anaesthesia, University College Hospital, London NW1 2BU, UK National Institute for Academic Anaesthesia's Health Services Research Centre, Royal College of Anaesthetists, 35 Red Lion Square, London WC1R 4SG, UK - - 2014
Previous studies have suggested that there may be long-term harm associated with postoperative complications. Uncertainty exists however, because of the need for risk adjustment and inconsistent definitions of postoperative morbidity. We did a longitudinal observational cohort study of patients undergoing major surgery. Case-mix adjustment was applied and morbidity was recorded ...
Lee Cheol Whan CW Department of Medicine, Asan Medical Center, University of Ulsan, Seoul, - - 2014
We investigated the temporal patterns of drug-eluting stents (DES) failure and its relationship with clinical outcomes in patients with DES failure. Time to DES failure is widely variable, but little information is available on the temporal patterns of DES failure and its impact on clinical outcomes. The angiographic patterns of ...
Wu Cynthia C Department of Medicine, University of Alberta, Edmonton, Alberta, Canada. Electronic address: - - 2014
The frequency and case fatality of venous thromboembolism (VTE) and major bleeding during the initial 3months of therapy in those treated for symptomatic VTE with either direct oral anticoagulants (DOACs) or vitamin K antagonists (VKA) are important clinically relevant outcomes. We sought to measure it during the initial months of ...
Kuwaki Hiroshi H Second Department of Internal Medicine, University of Occupational and Environmental Health, School of Medicine, Kitakyushu, - - 2014
This study sought to examine left atrial (LA) mechanics and the prognostic impact of patients with echocardiographic findings of E/A ratio ≤0.75, deceleration time (DcT) of mitral E-wave >140 ms, but E/ε' ≥10. Traditional diastolic dysfunction (DD) grading system could not classify every patient into a specific group. We considered the group ...
Callaghan John J JJ Department of Orthopaedic Surgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, 01029 JPP, Iowa City, IA, 52242, USA, - - 2014
Long-term evaluation of knee arthroplasty should provide relevant information concerning the durability and performance of the implant and the procedure. Because most arthroplasties are performed in older patients, most long-term followup studies have been performed in elderly cohorts and have had low patient survivorship to final followup; the degree to ...
Speziale Francesco F Vascular and Endovascular Surgery Unit, "Sapienza" University of - - 2014
Endovascular aneurysm repair (EVAR) has fast become the therapeutic strategy of choice for abdominal aortic aneurysms (AAA). Nowadays, the most important limit to the effectiveness of this technique is represented by complex anatomical situations, especially regarding the morphology of the proximal sealing zone. The aim of the present study was ...
Hunt Linda P LP Musculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Bristol, - - 2014
Understanding the risk factors for early death after knee replacement could help to reduce the risk of mortality after this procedure. We assessed secular trends in death within 45 days of knee replacement for osteoarthritis in England and Wales, with the aim of investigating whether any change that we recorded ...
Murakami Hironori H Division of Cardiology, Cardiovascular Center, Teine Keijinkai Hospital, Sapporo, Japan. Electronic address: - - 2014
The prevalence of severe sclerotic aortic stenosis (ScAS) in those at least ≧80 years old has been increasing in Japan; however, the prognosis of these Japanese patients without surgical treatment has not been reported. Ninety consecutive patients with medically treated severe ScAS were prospectively studied. To assess further event-free survival ...
Larsen Jacob M JM Department of Cardiology and Center for Cardiovascular Research, Aalborg University Hospital. Electronic address: - - 2014
Recalled St Jude Medical Riata defibrillator leads are prone to insulation failures with externalized conductors (EC). Longitudinal studies are needed to guide lead management. To describe the dynamic nature of EC and the association with electrical abnormalities and lead extraction outcomes. A nationwide cohort established in 2012 of 295 patients ...
Feng Yunlin Y Division of Nephrology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu 610072, - - 2014
Cystatin-C (CysC) has been demonstrated as a sensitive and reliable biomarker to predict the onset of acute kidney injury (AKI). However, few studies concerned about the relationship between CysC and the outcomes of AKI. To determine whether CysC elevation prior to definite diagnosis of AKI is related to higher prevalence ...
Ogihara Toshio T aMorinomiya University of Medical Sciences, Osaka bKeio University, Tokyo cOsaka University Graduate School of Medicine, Osaka dSapporo Medical University, Hokkaido eDokkyo Medical University fShin-Oyama City Hospital, Tochigi gTohoku University Graduate School of Medicine, Miyagi hEhime University Graduate School of Medicine, Ehime iKurume University School of Medicine, Fukuoka jUniversity of the Ryukyus School of Medicine, Okinawa kSaitama Medical University, Saitama lAsahi Rousai Hospital, Aichi mYokohama City University Graduate School of Medicine, Kanagawa nSapporo Nishimaruyama Hospital, Hokkaido oTokyo Medical University, Tokyo pKawasaki Medical School, Okayama qKanazawa University Hospital, Ishikawa, - - 2014
The aim of the present study was to compare the cardiovascular effects of olmesartan, an angiotensin II receptor blocker, combined with a calcium channel blocker (CCB) or a diuretic, in a prospective, randomized, open-label, blinded endpoint trial. Japanese hypertensive patients aged at least 65 to less than 85 years with ...
Sabate Rotes Anna A Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota; Departament de Pediatria, Universitat Autònoma de Barcelona, Barcelona, - - 2014
Surgical pulmonary valve replacement (PVR) in previously repaired tetralogy of Fallot (TOF) is frequently required. There are few data in large series of patients with long-term follow-up. Our aim was to review our 40-year experience with PVR after TOF repair and to evaluate prognostic factors for reintervention and death. Between ...
Ugare G U GU Department of Surgery, University of Calabar Teaching Hospital, Calabar, - - 2014
Aims and objectives: The objective of the following study is to analyze the trauma type (causes), injury pattern and factors that may have contributed to death within 72 h of admission into our emergency department (E.D). Materials and Methods: An 18 month prospective observational study, done from April 2009 to ...
Spargias Konstantinos K Departments of Transcatheter Heart Valves, Hygeia Hospital, Athens, - - 2014
Transcatheter aortic valve replacement (TAVR) is now an established treatment for certain patients with severe aortic valve stenosis (AS). However, as the number of patients screened for TAVR increases, many are found to have absolutely no option for peripheral artery access. Transaortic valve replacement (TAoVR) has been proposed as a ...
Hahn Rebecca T RT Columbia University Medical Center/New York Presbyterian Hospital, New York, New York. Electronic address: - - 2014
This study sought to characterize the patients receiving post-implantation balloon dilation (PD) following transcatheter aortic valve replacement (TAVR) and evaluate procedural outcomes in the PARTNER (Placement of Aortic Transcatheter Valve) I trial. Following TAVR, PD has been used to treat paravalvular regurgitation. The PARTNER I trial cohort A (n = 304) and ...
Fiorella D D Neurosurgery, Cerebrovascular Center, Stony Brook University Medical Center, Stony Brook, NY, - - 2014
The Low-profile Visualised Intraluminal Support (LVIS) Device is a novel, braided, intracranial microstent designed for stent-assisted coiling. We present the results of a single-arm, prospective, multicenter trial of the LVIS for the treatment of wide-necked intracranial aneurysms 31 patients with unruptured, wide-necked (neck >4 mm or dome : neck ratio ...
Kim J J University of Minnesota, Minneapolis, MN, - - 2014
Stent placement for extracranial vertebral artery (ECVA) stenosis has largely followed cardiac stent technology. However, it remains unclear whether the newer drug eluting stents (DES) have better outcomes than older non-drug eluting stents (NDES). Compare clinical outcomes (vertebrobasilar stroke, any stroke and any death) as well as restenosis rates between ...
Sahhaf Farnaz F Women's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, - - 2014
Postpartum haemorrhage (PPH) is the third-most common cause of maternal death in the United States and it is still the first prevalent cause of maternal death in developing countries. Active prevention of haemorrhage with an uterotonic or other new drugs leads to a decrease in postpartum vaginal haemorrhage. The aim ...
Dvir Danny D St Paul's Hospital, Vancouver, British Columbia, - - 2014
Owing to a considerable shift toward bioprosthesis implantation rather than mechanical valves, it is expected that patients will increasingly present with degenerated bioprostheses in the next few years. Transcatheter aortic valve-in-valve implantation is a less invasive approach for patients with structural valve deterioration; however, a comprehensive evaluation of survival after ...
Serra-Grima Ricard R Department of Cardiology, Hospital de la Santa Creu i Sant Pau, IIb-Sant Pau, Universitat Autónoma de Barcelona, Barcelona, - - 2014
Analyze the prevalence, clinical characteristics, and long-term outcome of early repolarization pattern (ERP) in elite athletes during professional activity and after retirement. ERP is considered a benign variant of the ECG, more frequent in athletes. However, prospective studies suggested that ERP is associated with an increased risk of sudden cardiac ...
Fokkema Margriet M *Department of Vascular Surgery, University Medical Center Utrecht, The Netherlands †Department of Vascular and Endovascular Surgery, Beth Israel Medical Center, Boston, MA ‡Experimental Cardiology Laboratory, University Medical Center Utrecht, Utrecht, the Netherlands §Interuniversity Cardiology Institute of the Netherlands, Utrecht, the Netherlands; and ¶Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The - - 2014
To study perioperative results and restenosis during follow-up of carotid artery stenting (CAS) versus carotid endarterectomy (CEA) for restenosis after prior ipsilateral CEA in an individual patient data (IPD) meta-analysis. The optimal treatment strategy for patients with restenosis after CEA remains unknown. A comprehensive search of electronic databases (Medline, Embase) ...
Nassar George M GM Dialysis Access Management Centers, Nephrology Dialysis and Transplantation Associates, The Kidney Institute & Houston Methodist Hospital, Weill Cornell University, Houston, - - 2014
Arteriovenous grafts (AVGs) suffer from high thrombosis rates. It is not known whether placement of stent grafts at the venous anastomosis (VA) of thrombosed AVGs would impact future thrombosis. This is a retrospective study evaluating a group of AVGs that underwent endovascular thrombectomy with placement of a stent graft at ...
Dillier Roger R German Heart Center Munich, Technical University, Munich, Germany - - 2014
-This study aimed to evaluate the safety of continuous periprocedural rivaroxaban administration during left atrial RFA in comparison with uninterrupted oral vitamin K antagonist (VKA) administration. Data about the use of rivaroxaban in the setting of left atrial radiofrequency catheter ablation (RFA) procedures are lacking. -The study cohort included 544 ...
Siempos Ilias I II Department of Medicine, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; First Department of Critical Care Medicine and Pulmonary Services, Evangelismos Hospital, University of Athens Medical School, Athens, Greece; Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medical College, New York, NY, USA. Electronic address: - - 2014
Delay of tracheostomy for roughly 2 weeks after translaryngeal intubation of critically ill patients is the presently recommended practice and is supported by findings from large trials. However, these trials were suboptimally powered to detect small but clinically important effects on mortality. We aimed to assess the mortality benefit of ...
Bisdas Theodosios T Department of Vascular Surgery, St. Franziskus Hospital and University Clinic of Muenster, Muenster, Germany. Electronic address: - - 2014
Several studies have confirmed the excellent early performance of the Endurant (Medtronic Endovascular, Santa Rosa, Calif) endoprosthesis to treat abdominal aortic aneurysms (AAAs). However, data about the long-term durability of the device are still lacking. We conducted this prospective two-center single-arm study to assess the late outcomes of the endograft ...
Boulware David R DR From the University of Minnesota, Minneapolis (D.R.B., D.B.M., M.A.R., K.H.H., D.A.W., R.R., J.R., M.W.L., K.N., T.L.B., P.R.B.); the Infectious Disease Institute (D.B.M., A.M., H.W.N., D.A.W., R.R., J.R., M.W.L., A.K., Y.C.M.) and School of Medicine, College of Health Sciences (D.B.M.), Makerere University, Kampala, and Mbarara University of Science and Technology, Mbarara (C.M., K.T.) - both in Uganda; the University of Cape Town, Cape Town, South Africa (C.S., F.T., G.M.); Johns Hopkins School of Medicine, Baltimore (Y.C.M.); the Mucosal and Vaccine Research Program Colorado (MAVRC), University of Colorado Denver, Aurora, and Denver Veterans Affairs Medical Center, Denver (E.N.J.); and Imperial College London, London - - 2014
Cryptococcal meningitis accounts for 20 to 25% of acquired immunodeficiency syndrome-related deaths in Africa. Antiretroviral therapy (ART) is essential for survival; however, the question of when ART should be initiated after diagnosis of cryptococcal meningitis remains unanswered. We assessed survival at 26 weeks among 177 human immunodeficiency virus-infected adults in ...
van Laar Jacob M JM Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United - - 2014
High-dose immunosuppressive therapy and autologous hematopoietic stem cell transplantation (HSCT) have shown efficacy in systemic sclerosis in phase 1 and small phase 2 trials. To compare efficacy and safety of HSCT vs 12 successive monthly intravenous pulses of cyclophosphamide. The Autologous Stem Cell Transplantation International Scleroderma (ASTIS) trial, a phase ...
Cowger Jennifer A JA Mechanical Circulatory Support and Transplant Program, St. Vincent Heart Center of Indianapolis, Indianapolis, Indiana. Electronic address: - - 2014
Although left ventricular assist device (LVAD) management strategies are undertaken to reduce the development of aortic insufficiency (AI), the effect of AI on patient morbidity and mortality is not known. Patients undergoing HeartMate II (Thoratec, Pleasanton, CA) implant were prospectively monitored with serial echocardiograms. Kaplan-Meier methods and log-rank testing were ...
Brunkwall J J Department of Vascular and Endovascular Surgery, University Clinics, University of Cologne, Cologne, Germany. Electronic address: - - 2014
Uncomplicated acute type B aortic dissection (AD) treated conservatively has a 10% 30-day mortality and up to 25% need intervention within 4 years. In complicated AD, stent grafts have been encouraging. The aim of the present prospective randomised trial was to compare best medical treatment (BMT) with BMT and Gore ...
Sánchez-Recalde Angel A Servicio de Cardiología, Hospital Universitario La Paz, Madrid, Spain. Electronic address: - - 2014
Percutaneous closure of paravalvular leakage is an alternative to surgery in high-risk patients, but its use has been limited by a lack of specific devices. More appropriate devices-like the Amplatzer Vascular Plug III-have recently been developed, but information about their efficacy and safety is still scarce. The objective of the ...
Lee Hsin-Fu HF Cardiovascular Division, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou, Taoyuan, - - 2014
Dilated inferior vena cava (IVC) is prevalent among patients with heart failure (HF), but whether its presence predicts worsening renal function (WRF) or adverse outcomes is unclear. This cohort study analyzed patients with left ventricular ejection fraction <40 % and repeated hospitalizations (≥2 times) for HF between August 2009 and August ...
Christersson Christina C Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, - - 2014
D-dimer is related to adverse outcome in arterial and venous thromboembolic diseases. To evaluate the predictive value of D-dimer for stroke, other cardiovascular event and bleedings, in patients with atrial fibrillation (AF) treated with oral anticoagulation with apixaban or warfarin; and to evaluate the relationship between the D-dimer levels at ...
Ohno Yohei Y Department of Cardiology, Ferrarotto Hospital, University of Catania, Via Citelli 29, Catania 95124, Italy Department of Cardiology, University of Tokai School of Medicine, Isehara, - - 2014
The aim of this study was to evaluate the association of baseline tricuspid regurgitation (TR) on the outcomes after percutaneous mitral valve repair (PMVR) with the MitraClip system. Data from 146 consecutive patients with functional mitral regurgitation (MR) were obtained. Two different groups, dichotomized according to the degree of pre-procedural ...
Calloway James J JJ Department of Internal Medicine, Hospital for Special Surgery and Weill Cornell Medical College, New York, NY, USA. Electronic address: - - 2014
The aim was to investigate the association between continuing angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARB) with postinduction hypotension and vasoactive drug use in elderly orthopedic surgery patients under regional anesthesia. Retrospective design consisted of 114 patients (mean age 66) undergoing elective total knee arthroplasty, including 84 patients ...
Hwang Ho Young HY Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul, Republic of - - 2014
Previous studies have compared the outcomes of mitral annuloplasty with those of mitral valve replacement in patients with functional mitral regurgitation. However, data comparing the results of tricuspid annuloplasty (TAP) with those of tricuspid valve replacement (TVR) in patients with functional tricuspid regurgitation (FTR) have been scarce. We evaluated whether ...
Paradisi Andrea A Health Services Research Unit, IDI-IRCCS, Rome, Italy. Electronic address: - - 2014
Toxic epidermal necrolysis (TEN) is a severe and potentially lethal drug reaction for which no standard treatment is available. To describe a case series of patients with TEN treated with a single dose of etanercept. We observed 10 consecutive patients with TEN. For each patient, we recorded the presence of ...
Chang Chia-Hsuin CH Institute of Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. Electronic address: - - 2014
Carotid angioplasty and stent (CAS) placement has emerged as an attractive revascularization strategy for patients with internal carotid artery stenosis. However, the effectiveness and safety of CAS were not fully evaluated, mainly because of methodological difficulties in finding an appropriate comparison group. Patients who underwent CAS were identified from Taiwan's ...
Gotzmann Michael M BG-Kliniken Bergmannsheil, Department of Cardiology and Angiology, Ruhr-University Bochum, Bochum, Germany. Electronic address: - - 2014
There is little known about the long-term results of the CoreValve prosthesis. The aim of this study was to assess the 3-year clinical and hemodynamic outcomes of the CoreValve prosthesis. One hundred fifty consecutive patients with severe aortic stenosis successfully underwent transcatheter aortic valve implantation (TAVI) with the CoreValve prosthesis. ...
Pedersen W R WR Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital Minneapolis, MN, USA - - - 2014
Balloon aortic valvuloplasty (BAV) has reemerged with transcatheter valve therapy. Cylindrical balloons have been the device of choice despite limitations. An hour glass shaped balloon may permit enhanced fixation and broader leaflet opening without annular compromise. We report our initial BAV experience using the V8 balloon (InterValve Inc.) in 20 ...
Miura Takashi T 1 Department of Cardiovascular Medicine, Shinshu University School of Medicine, Matsumoto, - - 2014
Purpose : To examine the prognosis of patients with intermittent claudication who received treatment with endovascular techniques. Methods : A retrospective multicenter study was performed involving 2930 consecutive patients (2307 men; mean age 71.5±8.9 years) with intermittent claudication who underwent an endovascular procedure for a de novo iliofemoral artery lesion. ...
Greason Kevin L KL Mayo Clinic, Rochester, Minnesota. Electronic address: - - 2014
The Placement of Aortic Transcatheter Valves (PARTNER) trial reported a reduced rate of mortality in patients with previous coronary bypass grafting (CABG) operation who received surgical aortic valve replacement (SAVR) in comparison with transcatheter aortic valve replacement (TAVR). We sought to further evaluate these groups. We reviewed the database of ...
Shi Guocheng G Department of Cardiothoracic Surgery, Shanghai Children's Medical Center, Heart Center, Shanghai Jiaotong University School of Medicine, Shanghai, - - 2014
Management of complete atrioventricular (AV) septal defect (CAVSD) with a large ventricular component (>1 cm) remains controversial. The purpose of this study was to assess the feasibility of the one-and-a-half patch technique in repairing this lesion. This was a retrospective review of patients undergoing surgical repair of CAVSD with a ...
Hong Tsai-Hsia - - 2014
Sepsis causes high mortality, and the mortality due to secondary infections is even higher. No studies to date have investigated the time from the primary infection to death due to a secondary infection; similarly, the factors that are significantly different in sepsis survivors relative to non-survivors or in severe sepsis ...
Lee Sarah J - - 2014
Surviving Sepsis guidelines recommend early aggressive fluid resuscitation within six hours of sepsis onset time. Though rapid fluid administration may offer benefit, studies on the timing of resuscitation are lacking. There is an association between quicker, adequate fluid resuscitation and patient outcome from sepsis onset time. This is a retrospective ...
Findlay J M JM Oxford OesophagoGastric Centre, The Joint Research Office, Churchill Hospital, Oxford, - - 2014
Enhanced recovery after surgery (ERAS) pathways aim to accelerate functional return and discharge from hospital. They have proven effective in many forms of surgery, most notably colorectal. However, experience in esophagectomy has been limited. A recent study reported significant reductions in pulmonary complications, mortality, and length of stay following the ...
Tsivgoulis G G Second Department of Neurology, 'Attikon' Hospital, University of Athens, School of Medicine, Athens, Greece; Department of Neurology, Democritus University of Thrace, School of Medicine, Alexandroupolis, Greece; International Clinical Research Center, St Anne's University Hospital in Brno, Brno, Czech - - 2014
Although the latest recommendations suggest that carotid endarterectomy (CEA) should be performed in symptomatic carotid artery stenosis (sCAS) patients within 2 weeks of the index event, only a minority of patients undergo surgery within the recommended time-frame. The aim of this international multicenter study was to prospectively evaluate the safety of ...
Xun Yun-Hao YH Department of Liver Diseases, Xixi Hospital of Hangzhou, Hangzhou, Zhejiang, - - 2014
Nonalcoholic fatty liver disease (NAFLD) fibrosis score (NFS) has emerged as a useful predictor for a long-term outcome in NAFLD patients. We evaluated the predictive performance of NFS for overall mortality in a Chinese population with NAFLD. All ultrasonography-diagnosed NAFLD patients at our center between 1996 and 2011 were retrospectively ...
Ndrepepa Gjin G Deutsches Herzzentrum, Lazarettstrasse 36, 80636, Munich, Germany, - - 2014
The association between bleeding and timing of mortality after percutaneous coronary intervention (PCI) remains poorly investigated. We aimed to investigate the impact of bleeding on early (30-day) and late (30-day to 1 year) mortality after PCI. The study includes 14,180 patients. Bleeding within 30 days after PCI was defined using the Bleeding ...
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