Search Results
Results 151 - 200 of 1511
1 2 3 4 5 6 7 8 9 10 >
Valente Jonathan H JH Jonathan H. Valente, MD, is an Associate Professor in the Department of Emergency Medicine at The Alpert Medical School of Brown University and Rhode Island Hospital, and Hasbro Children's Hospital, Providence, Rhode Island. Gregory D. Jay, MD, PhD, is a Professor in the Department of Emergency Medicine at The Alpert Medical School of Brown University and Rhode Island Hospital in Providence, Rhode Island. He has received grant/research funding from the NIH and AHRQ in the past and is receiving funding from those same organizations currently. He is a consultant/advisor to Covidien (Mansfield, Massachusetts). Christopher P. Zabbo, DO, is the Program Director of the Emergency Medicine Residency at Kent Hospital in Warwick, Rhode Island, and a Clinical Assistant Professor at the University of New England College of Osteopathic Medicine in the Department of Emergency Medicine at Kent Hospital in Warwick, Rhode Island. Steven E. Reinert, MS, is a Research Analyst at Lifespan Information Services in Providence, Rhode Island. Karina Bertsch, MSW, is the Clinical Research Program Administrator at Rhode Island Hospital in - - 2014
The purpose of this study was to compare cosmesis at 3 to 4 months and infection in simple lacerations irrigated with normal saline (NS) versus activated chlorine dioxide (CD). This was a prospective, randomized trial of a convenience sample of patients. This study was approved by the institutional review board ...
Divoky Laura L Department of Internal Medicine, Summa Health System, 75 Arch St, Suite #501, Akron, OH 44304-1424. - - 2014
Myopericarditis occurs in 15% of patients with pericarditis. Recurrent myopericarditis occurs in 15% to 30% of patients after partial or complete recovery from acute myopericarditis. Relapse often occurs within 1 month of an initial episode. The standard of care for pericarditis or myopericarditis is initial treatment with nonsteroidal anti-inflammatory drugs ...
Gilbert Erin - - 2014
There are numerous dermal fillers available to injectors in the US and Europe for the correction of age-related volume loss in the midface and perioral regions. Product availability differs between these two aesthetic markets due to US Food and Drug Administration (FDA) regulatory requirements. The purpose of this study is ...
Obal Detlef D Department of Anesthesiology and Perioperative Medicine and the Center for Diabetes and Obesity Research, University of Louisville, Louisville, KY. Electronic address: - - 2014
To test the primary hypothesis that ondansetron or dolasetron extends the rate-corrected QT electrocardiographic interval (QTc) greater than 60 milliseconds or increases the fraction of patients with QTc greater than 500 milliseconds in patients having noncardiac surgery, and the secondary hypothesis that QTc prolongation is worse in diabetic patients. We ...
Cevik Arif A AA Department of Emergency Medicine, Eskisehir Osmangazi University, Meselik, Eskisehir, - - 2014
The aim of our study was to evaluate the effect of lactate level (LL) and shock index (SI) on the outcome in nontraumatic hypotensive patients in the emergency department, and also to show the significance of the combined usage of these two parameters. This is a prospective, observational study. Elevated ...
Ascioglu Sibel S Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of - - 2014
Both caspofungin and voriconazole were initially approved by the FDA with very narrow indications. Our aim was to evaluate the utilization patterns and comparative effectiveness of these agents early after marketing before any labeling change occurred. This was a retrospective cohort study utilizing a large healthcare database in the United ...
Sivrikoz Nükhet N Department of Anesthesiology, İstanbul University İstanbul Faculty of Medicine, İstanbul, - - 2014
Objective: Non-steroidal anti-inflammatory drugs (NSAIDs) are recommended for multimodal postoperative pain management. The purpose of this study was to evaluate the postoperative pain relief and opioid-sparing effects of dexketoprofen and lornoxicam after major orthopedic surgery. Methods: After obtaining ethical committee approval and informed consent, 120 patients undergoing elective hip or ...
Eris Cuneyt C Department of Cardiovascular Surgery, Bursa Yuksek Ihtisas Education and Research Hospital Bursa, - - 2014
Levosimendan (LS) is a new inotropic drug which belongs to the group of drugs known as calcium sensitizers. It is different from other inotropic agents by its inotropic and vasodilatory actions without an increase in myocardial oxygen consumption and considered as a good choice in high-risk patients undergoing cardiac surgery. ...
Mandal Pragnadyuti P Department of Pharmacology, Midnapore Medical College, Paschim Medinipur, West Bengal, - - 2014
Post-operative nausea and vomiting (PONV) frequently hampers implementation of ambulatory surgery in spite of so many costly antiemetic drugs and regimens. The study was carried out to compare the efficacy of ginger (Zingiber officinale) added to Ondansetron in preventing PONV after ambulatory surgery. It was a prospective, double blinded, and ...
Isitemiz Ilke I Department of Anesthesiology and Reanimation, Haseki Training and Research Hospital, Istanbul, - - 2014
Background In this retrospective comparative study, we aimed to compare the effectiveness of fentanyl, midazolam, and a combination of fentanyl and midazolam to prevent etomidate-induced myoclonus. Material and Methods This study was performed based on anesthesia records. Depending on the drugs that would be given before the induction of anesthesia ...
Shah B B Chief Cardiac Anesthesiologist, SAL Hospital, Ahmadabad, Gujarat, - - 2014
Levosimendan is a calcium sensitizer drug which has been used in cardiac surgery for the prevention of postoperative low cardiac output syndrome (LCOS) and in difficult weaning from cardiopulmonary bypass (CPB). This study aims to evaluate perioperative hemodynamic effects of levosimendan pretreatment in patients for off-pump coronary artery bypass graft ...
Deshpande N V NV Director-Cardiac Cath Lab, Spandan Heart Institute and Research Center, Nagpur, - - 2014
Drug eluting stents have remarkably improved results of percutaneous coronary angioplasty. Most of the currently available drug eluting stents uses a durable polymer as drug carrier which has been implicated in local inflammatory response and continued incidence of late and very late stent thrombosis. The Pronova XR stent is one ...
Robati Shibby S Department of Trauma and Orthopaedics, East Kent University Hospitals, Margate, - - 2014
A 72-year-old woman was admitted for a routine elective total knee replacement. By day 1 postoperative, she became hyponatraemic following an Addisonian crisis, leading to an admission into the intensive therapy unit (ITU). It was later during this stay in the ITU and on a retrospective drug history review that ...
Kuramitsu Shoichi S Department of Cardiology, Kokura Memorial Hospital, Kitakyushu, - - 2014
Stent fracture (SF) after drug-eluting stent implantation has become an important concern. The aim of this study was to assess the incidence, predictors, and clinical impact of SF after biolimus-eluting stent. A total of 1026 patients with 1407 lesions undergoing the Nobori biolimus-eluting stent implantation and follow-up angiography within 9 ...
Fallah Razieh R Department of Pediatrics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran ; Growth Disorders of Children Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, - - 2014
Infantile spasms (IS) are among the most catastrophic epileptic syndromes of infancy. The purpose of this study was to compare efficacy and safety of topiramate (TPM) and nitrazepam (NZP) as first-line drugs in the treatment of IS. In a parallel single-blinded randomized clinical trial, 50 patients with IS referred to ...
Kaja Sriramamurthy S Department of Anesthesia, Mahadevappa Rampure Medical College, Gulbarga, Karnataka, - - 2014
Post-operative nausea and vomiting is one of the most common and distressing complications after anesthesia and surgery. It may lead to serious post-operative complications. Ramosetron is a newer 5-HT3 receptor antagonist and has more potent and longer duration of antiemetic effects compared to first generation 5HT3 receptor antagonists. The purpose ...
Casaroli-Marano Ricardo R 0000-0002-1431-4874 Instituto Clinic de Oftalmología, Hospital Clínic de Barcelona, Universitat de Barcelona, Carrer Sabino Arana 1, 08028 Barcelona, - - 2014
Purpose. To survey the management of patients with neovascular age-related macular degeneration (nvAMD) in Spain. Methods. An observational retrospective multicenter study was conducted. The variables analyzed were sociodemographic characteristics, foveal and macular thickness, visual acuity (VA), type of treatment, number of injections, and the initial administration of a loading dose ...
Tewari Anurag A Department of Anesthesiology, Dayanand Medical College, Ludhiana, - - 2014
Under regional anesthesia, geriatric patients are prone to shivering induced perioperative complications that Anesthesiologists should prevent rather than treat. We investigated the prophylactic efficacy of oral tramadol 50 mg to prevent the perioperative shivering after transurethral resection of prostate (TURP) surgery under subarachnoid blockade (SAB). Shivering is usually overlooked in ...
Yoganarasimha N N Department of Anaesthesiology, Adichunchanagiri Institute of Medical Sciences, Mandya, Karnataka, - - 2014
Spinal anaesthesia requires a small volume of drug to produce profound reproducible sensory analgesia and motor blockade, but has limited duration of action. A properly chosen adjuvant to local anaesthetic agent produces the best way to achieve a better quality regional block. Hence, a study was conducted to compare the ...
Kitamura Shin S Department of Internal Medicine, Nippon Medical School Musashikosugi - - 2014
Aim: Memantine hydrochloride (Memary(®)), launched in June 2011 in Japan, is used in patients with moderate to severe Alzheimer's disease. We performed an integrated analysis of data obtained from different clinical studies of memantine hydrochloride conducted between 2002 and 2011 in Japan in order to examine the long-term tolerability and ...
Khalili Gholamreza G Anesthesiology and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, - - 2014
Post-operative shivering is an unpleasant complication that various drugs are used to prevent and treat. It is tried to advice a suitable drug with the least side-effects. This study was carried out to examine the effect of intravenous Apotel on the post-operative shivering and core and peripheral body temperature. This ...
Chevreul Karine K URC Eco Île-de-France (AP-HP), Hôtel Dieu, Paris, France; Inserm, ECEVE, U1123, Paris, France; Univ Paris Diderot, Sorbonne Paris Cité, ECEVE, UMRS 1123, Paris, - - 2014
To estimate annual direct costs of early RA by resource component in an inception cohort, with reference to four distinct treatment strategies: no disease modifying antirheumatic drugs (DMARDs), synthetic DMARDs only, biologic DMARDs in the first year ('first-year biologic', FYB), and biologic DMARDs from the second year after inclusion ('later-year ...
Akshat Shiv S Department of Anaesthesiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, - - 2014
Introduction. Pain is the commonest morbidity after open surgical procedures. The most effective treatment of postoperative pain is opioid therapy. Morphine, the commonly used opioid, is associated with many side effects including respiratory depression, sedation, postoperative nausea vomiting, and pruritus. Nalbuphine, on the other hand, is known to cause less ...
Terauchi Gaku G Department of Ophthalmology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-0003, - - 2014
Background. To report the outcome of pars plana vitrectomy (PPV) combined with intraoperative endolaser focal photocoagulation (PC) on eyes with idiopathic macular telangiectasis (MacTel) type 1. Methods. This was a retrospective study of two female patients with MacTel type 1 who were resistant to focal photocoagulation, sub-Tenon triamcinolone injection, and/or ...
An Guipeng G 1. The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong 250012, China; ; 2. Department of cardiology, Shandong University Qilu Hospital, Jinan, Shandong 250012, - - 2014
Objective We lack data on the long-term outcome of drug-eluting stenting in patients with early-onset coronary artery disease (CAD). Here, we investigated the association of traditional risk factors and major adverse cardiovascular events (MACEs) after drug-eluting stenting in patients with CAD who were < 50 years old. Methods We enrolled ...
Ostyn Bart B Department of Public Health, Institute of Tropical Medicine, Antwerp, - - 2014
High frequency of relapse in miltefosine-treated visceral leishmaniasis (VL) patients in India and Nepal followed up for twelve months. To identify epidemiological and clinical risk factors for relapse of VL in patients recently treated with standard dosing of miltefosine in India and Nepal. Prospective observational study in three Primary Health ...
Chen Shin-Yan SY Department of Anesthesiology, Shuang Ho Hospital, Taipei Medical University, New Taipei City 10361, - - 2014
Purpose. The purpose of this study was to compare the analgesic properties of levobupivacaine with or without fentanyl for patient-controlled epidural analgesia after Cesarean section in a randomized, double-blinded study. Methods. We enrolled American Society of Anesthesiologists class I/II, full-term pregnant women at National Taiwan University Hospital who received patient-controlled ...
Menard Marie-Line ML University Department of Child and Adolescent Psychiatry, Nice Children's Hospitals CHU-Lenval, 57 avenue de la Californie, 06200 Nice, - - 2014
The prescription of antipsychotics (AP), and especially second generation AP, is increasing worldwide in the pediatric population. Most prescriptions are off-label and despite the identification of frequent and potentially severe adverse events (AE), there are only a few guidelines for the safety management. France is one of the countries with ...
Cohen Stephen M SM Atlanta Colon and Rectal Surgery, PA, Atlanta, GA, - - 2014
Postsurgical pain management remains a significant challenge. Liposome bupivacaine, as part of a multimodal analgesic regimen, has been shown to significantly reduce postsurgical opioid consumption, hospital length of stay (LOS), and hospitalization costs in gastrointestinal (GI) surgery, compared with intravenous (IV) opioid-based patient-controlled analgesia (PCA). Pooled results from open-label studies ...
Roongpisuthipong Wanjarus W 0000-0003-1658-1957 Division of Dermatology, Department of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok 10300, - - 2014
Background. Stevens-Johnson syndrome (SJS) and/or toxic epidermal necrolysis (TEN) are uncommon and life-threatening drug reaction associated with a high morbidity and mortality. Objective. We studied SJS and/or TEN by conducting a retrospective analysis of 87 patients treated during a 10-year period. Methods. We conducted a retrospective review of the records ...
Akpaloo Wisdom W AngloGold Ashanti Hospital, P.O. Box 10, Obuasi, Ghana ; Florence Nightingale School of Nursing and Midwifery, King's College London, London SE1 8WA, - - 2014
Malaria contributes significantly to the global disease burden. The World Health Organization recommended the use of artemisinin-based combination therapies (ACTs) for treatment of uncomplicated falciparum malaria a decade ago in response to problems of drug resistance. This review compared two of the ACTs-Dihydroartemisinin-Piperaquine (DP) and Artemether-Lumefantrine (AL) to provide evidence ...
Sobel Rachel E RE Pfizer Inc, 235 East 42nd St, MS#219-9-1, New York, NY 10017, - - 2014
This study aimed to assess long-term safety and developmental data on juvenile idiopathic arthritis (JIA) patients treated in routine clinical practice with celecoxib or nonselective nonsteroidal anti-inflammatory drugs (nsNSAIDs). Children aged ≥2 to <18 years with rheumatoid-factor-positive or -negative polyarthritis, persistent or extended oligoarthritis, or systemic arthritis were enrolled into this ...
Jarahzadeh Mohammad Hossein MH Department of Anesthesiology and Critical Care, Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, - - 2014
Thiopental sodium and Propofol are two widely-used drugs in the induction of anesthesia in assisted reproductive technology (ART). However, the side effects and outcome of recovery from anesthesia of these drugs on ART have not been identified yet. This study aimed at investigating the side effects and hemodynamic effects of ...
Han Shilong S Department of Interventional & Vascular Surgery, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, - - 2014
Drug eluting beads (DEB) are relatively new embolic agents that allow sustained release of chemotherapeutic agents in a localized fashion to the tumor. This technique is associated with reduced systemic side effects relative to systemic chemotherapy and an increase in the dose of antineoplastic agent delivered to the lesion. The ...
Durand Eric E From the Cardiology Department, European Georges Pompidou Hospital, Paris Centre de Recherche Cardiovasculaire, INSERM U 970, Université Paris-Descartes, Paris, France (E.D., M.R., A.L.); Faculty of Pharmacy, Institut Charles Gherardt, MACS (T.S.) UMR CNRS 5253 and Faculty of Pharmacy, Research Center for Artificial Biopolymers, Institut de Biomolecules Max Mousseron, University Montpellier 1-CNRS, Montpellier, France (M.V.); AccelLAB Inc, Boisbriand, Quebec, Canada (G.L.); and Arterial Remodeling Technologies, Noisy le Roi, France - - 2013
We aimed to evaluate a new drug-free fully bioresorbable lactic acid-based scaffold designed to allow early dismantling synchronized with artery wall healing in comparison with a bare metal stent (BMS). Twenty-three BMS (3.0×12 mm) and 36 lactic acid-based bioresorbable scaffolds (BRS, 3.0×11 mm) were implanted in porcine coronary arteries. QCA ...
Kim Jeong Ho JH Department of Gastroenterology, Yeouido St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, - - 2014
The use of proton pump inhibitors or misoprostol is known to prevent the gastrointestinal complications of nonsteroidal anti-inflammatory drugs (NSAIDs). Rebamipide is known to increase the mucosal generation of prostaglandins and to eliminate free oxygen radicals, thus enhancing the protective function of the gastric mucosa. However, it is unknown whether ...
Alfonso Fernando F Hospital Universitario de la Princesa, Madrid, Spain; Hospital Universitario Clínico San Carlos, Madrid, Spain. Electronic address: - - 2013
We sought to compare the efficacy of drug-eluting balloons (DEB) and everolimus-eluting stents (EES) in patients with bare-metal stent (BMS) in-stent restenosis (ISR). Treatment of patients with ISR remains a challenge. This was a prospective, multicenter, randomized trial comparing DEB and EES in patients with BMS-ISR. The primary end-point was ...
van Zellem Lennart L 1Division of Paediatric Intensive Care, Department of Paediatrics, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands. 2Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The - - 2013
To investigate whether analgesic and sedative drug use during PICU treatment is associated with long-term neurodevelopmental outcome in children who survived meningococcal septic shock. This study concerned a secondary analysis of data from medical and psychological follow-up of a cross-sectional cohort of all consecutive surviving patients with septic shock and ...
Villwock Jennifer A JA Department of Otolaryngology, SUNY Upstate Medical University, Syracuse, New - - 2013
The timing of tracheostomy in stroke patients unable to protect their airway has become a topic of debate. Proponents for early tracheostomy (ET) cite benefits including less ventilation-associated pneumonia, less sedative drug use, shorter length of stay, and reduced mortality in comparison with late tracheostomy (LT). We examined the timing ...
Zhang Peng P Department of Spine Surgery, The Third Hospital of Hebei Medical University, 139 Ziqiang Road, Shijiazhuang, 050051, - - 2013
To determine the outcome and safety of surgical treatment of thoracic and lumbar spinal tuberculosis in patients without obvious clinical and laboratory improvement after preoperative short-time chemotherapy. Data of 86 patients with single-level thoracic and lumbar tuberculosis, treated by one-stage posterior instrumentation combined with anterior radical debridement and fusion, were ...
Baek Chung Hee CH Division of Nephrology, Department of Internal Medicine, Asan Medical Center University of Ulsan College of Medicine, Seoul, Republic of - - 2014
Cardiovascular disease is an important cause of death in patients with end-stage renal disease. Although coronary artery bypass graft (CABG) surgery and drug-eluting stent (DES) implantation have been compared in chronic hemodialysis patients, the results are unclear. The study population consisted of chronic hemodialysis patients (dialysis duration >6 months) with coronary ...
Puustinen Juha J Department of Family Medicine, University of Turku, Lemminkäisenkatu 1, 20014, Turku, Finland, - - 2013
The aim of this study was to assess the effect of withdrawal from the long-term use of temazepam, zopiclone or zolpidem as hypnotics drugs (here referred to as BZD) on cognitive performance. Ninety-two adults (age ≥55 years) with primary insomnia and who were long-term daily users of BZD volunteered to participate ...
Hajjej Zied Z Intensive Care Unit, Military Hospital of Tunis, 1008 Montfleury, Tunis, Tunisia. Electronic address: - - 2013
Although there are many studies about catheter related infection in industrialized countries, very few have analyzed it in emerging countries. The aim of our study was to determine the incidence, microbiological profile and risk factors for catheter-related bloodstream infection (CRBSI) in a Tunisian medical intensive care unit. Over eight months ...
Tercan Mehmet M Anesthesiology and Reanimation Department, Medical Faculty, Uludag University, Bursa, - - 2014
We aimed to investigate the effects of metoclopramide and ondansetrone on mivacurium neuromuscular blockade. Seventy five, ASA I-II patients, aged 18-65 and scheduled for elective surgery requiring tracheal intubation were included in the study. The patients received metoclopramide 10mg, ondansetrone 4mg or normal saline 5mL; group M, group O, group ...
Kimmons Lauren A - - 2013
Dabigatran etexilate, an oral direct thrombin inhibitor, was approved by the Food and Drug Administration to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation based on the outcomes of the Randomized Evaluation of Long-term anticoagulant therapY (RE-LY) study. Although this study provides robust data ...
Vreden Stephen Gs SG Foundation for Scientific Research Suriname, Suriname, - - 2013
The emerging resistance to artemisinin derivatives that has been reported in South-East Asia led us to assess the efficacy of artemether-lumefantrine as the first line therapy for uncomplicated Plasmodium falciparum infections in Suriname. This drug assessment was performed according to the recommendations of the World Health Organization in 2011. The ...
Valgimigli Marco M Cardiology Department, University of Ferrara, Ferrara, Italy. Electronic address: - - 2013
This study sought to assess device-specific outcomes after implantation of bare-metal stents (BMSs), zotarolimus-eluting Endeavor Sprint stents (ZES-Ss), paclitaxel-eluting stents (PESs), or everolimus-eluting stents (EESs) (Medtronic Cardiovascular, Santa Rosa, CA) in all-comer patients undergoing percutaneous coronary intervention. Few studies have directly compared second-generation drug-eluting stents with each other or with ...
Holland Professor Richard - - 2013
Supervised consumption of opioid maintenance treatment (OMT) is standard in many drug centres reducing drug diversion, but is costly. We aimed to determine whether supervised consumption of OMT improved retention and other measures of drug use. Pragmatic randomised controlled trial comparing three months of daily supervised consumption of OMT with ...
Gamble John-Michael - - 2013
The aim of this study was to assess the impact of removing prior-authorization restrictions on the use of thiazolidinediones (TZDs) and outcomes. In a controlled interrupted time-series analysis, whereby new users of antidiabetic agents over 65 years of age in adjacent Canadian provinces with different TZD-related policies [Alberta (n=16,653) and ...
DU Li-Qun - - 2013
Glaucoma filtering surgery (GFS) is the most common procedure performed in the treatment of glaucoma. Although antiscarring agents help prevent postsurgical scarring and improve glaucoma surgical outcomes, they may be associated with an increased incidence of severe and potentially blinding complications. Poly(DL-lactide-co-glycolide) (PDLLA/GA) is a bioresorbable polymer, which can be ...
1 2 3 4 5 6 7 8 9 10 >