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Regimbeau Jean Marc JM Division of Digestive Surgery, Amiens University Medical Center, Amiens, France2Jules Verne University of Picardie, Unit EA4294, Amiens, France3Clinical Research Center, Amiens University Medical Center, Amiens, - - 2014
Ninety percent of cases of acute calculous cholecystitis are of mild (grade I) or moderate (grade II) severity. Although the preoperative and intraoperative antibiotic management of acute calculous cholecystitis has been standardized, few data exist on the utility of postoperative antibiotic treatment. To determine the effect of postoperative amoxicillin plus ...
Ruta David J DJ Division of Foot and Ankle Surgery, Department of Orthopaedic Surgery, University of Michigan Health Systems, 2098 South Main Street, Ann Arbor, MI, 48103, - - 2014
The CDC estimates 23% of healthcare-associated infections to be surgical site infections, with alarming prevalence of antibiotic-resistant organisms. While there is consensus regarding preoperative prophylaxis, orthopaedic surgeons' use of prophylactic postoperative oral antibiotics is less defined. We investigated surgeons' use of prophylactic postoperative oral antibiotics after elective outpatient foot or ...
Ponce Brent B Division of Orthopaedic Surgery, University of Alabama at Birmingham, 1313 13th Street South, Suite 203, Birmingham, AL 35205-5327. E-mail address: - - 2014
Prophylactic antibiotics decrease surgical site infection (SSI) rates, and their timing, choice, and discontinuation are measured and reported as part of the Surgical Care Improvement Project (SCIP). The aim of this study was to assess the comparative effectiveness of the SCIP-approved antibiotics for SSI prevention.METHODS: This retrospective cohort study utilized ...
Ishtiaque Khan Khizar K Buraidah Central Hospital, Buraidah, Al-Qaseem, Saudi Arabia. Electronic address: - - 2014
Role of prophylactic antibiotics in Milligan Morgan hemorrhoidectomy - A prospective, randomized control trial. Randomized control trial. Combined Military Hospital Malir, Bannu and HIT hospital Taxila, September 2008 to February 2011. Patients undergoing Milligan Morgan hemorrhoidectomy for grade III and IV hemorrhoids were randomized in 2 groups by using computer ...
Winton M M Leeds Neonatal Service, Leeds Teaching Hospitals NHS Trust, Leeds, - - 2014
A rational approach to managing babies at risk of early onset sepsis continues to challenge neonatal units. In August 2012 NICE published guidance on antibiotics for early onset sepsis in neonates.(1) We review our unit's performance in implementing the NICE guidance. Baseline assessment using the NICE tool had been completed ...
Teshima Hideki H Cardiovascular Surgery, Chikamori Hospital Heart Center, 1-1-16 Ohkawasuji, Kochi, 780-8522, Japan, - - 2014
This study was designed to compare the mid-term outcomes after aortic valve replacement (AVR) between 17-mm mechanical heart valves (MV) and 19-mm bioprosthetic valves (BV) in elderly patients with small aortic annuli. Between 2000 and 2011, 127 consecutive patients (mean age 79 years; 87 % female) underwent AVR for aortic valve stenosis ...
Bell Samira S Renal Unit, Ninewells Hospital, National Health Service Tayside, Dundee, United Kingdom; Population Health Sciences Division, Medical Research Institute, University of Dundee, Dundee, United Kingdom; - - 2014
In 2009, the Scottish government issued a target to reduce Clostridium difficile infection by 30% in 2 years. Consequently, Scottish hospitals changed from cephalosporins to gentamicin for surgical antibiotic prophylaxis. This study examined rates of postoperative AKI before and after this policy change. The study population comprised 12,482 adults undergoing ...
Vu Lan T LT Department of Surgery, University of California, 513 Parnassus Avenue, HSW 1601, San Francisco, CA, 94143-0570, USA, - - 2014
The purpose is to determine whether use of perioperative antibiotics for more than 24 h decreases the incidence of SSI in neonates and infants. We studied neonates and infants who had clean-contaminated or contaminated gastrointestinal operations from 1996 to 2006. Patient- and operation-related variables, duration of perioperative antibiotics, and SSI within ...
Senaratne Janek M JM Division of Cardiac Sciences, Grey Nuns Hospital, Edmonton, Alberta, - - 2014
Although the incidence of pacemaker-related infection (PMINF) is low, it necessitates removal of the pacing system. There is currently no consensus on antibiotics during implantation. A prospective database on patients undergoing pacemaker surgery from 1991 to 2009 was reviewed to determine factors associated with PMINF. Specifically, three eras of antibiotic ...
Rosa Regis G RG Infectious Diseases Division of Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, - - 2014
Background: Time to antibiotic administration (TTA) has been proposed as a quality-of-care measure in febrile neutropenia (FN); however, few data regarding the impact of TTA on mortality of adult cancer patients with FN are available.Objective: To determine whether TTA is a predictor of mortality in adult cancer patients with FN.Methods: ...
Lee Young H YH Department of Dermatology, Division of Health Services Research. Electronic address: - - 2014
Duration of oral antibiotic therapy in acne has not been widely studied. Recent guidelines suggest it should be limited to 3 to 6 months. We sought to compare the duration of oral antibiotic use with recent guidelines and determine the potential cost-savings related to shortened durations. This is a retrospective ...
Mazaki Takero T Department of Surgery, Nihon University School of Medicine, Tokyo, Japan. Electronic address: - - 2014
The efficacy of antibiotic prophylaxis for the prevention of surgical-site infection (SSI) after open tension-free inguinal hernia repair remains controversial. A double-blind, randomized, placebo-controlled trial was conducted. Patients who underwent elective open mesh-plug hernia repair were eligible for randomization. In the antibiotic prophylaxis group, 1.0 g cefazolin was intravenously administrated ...
Andreoli Arianna A Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, - - 2014
While traditionally surgery has dominated the clinical management of Buruli ulcer (BU), the introduction of the combination chemotherapy with oral rifampicin and intramuscular streptomycin greatly improved treatment and reduced recurrence rates. However management of the often extensive lesions after successful specific therapy has remained a challenge, in particular in rural ...
Gyorfi Justin R JR Division of Urology, Penn State Milton S. Hershey Medical Center, 500 University Drive, H055, Hershey, PA, 17033-0850, - - 2014
The purpose of the study was to evaluate whether a peri-procedural povidone-iodine rectal preparation (PIRP) prior to transrectal ultrasound-guided prostate needle biopsy (TRUS PNB) can reduce microorganism colony counts and infectious complications. Our institutional TRUS PNB database was reviewed to identify infectious post-biopsy complications (defined as fever >38.5 °C with positive culture). ...
Garofalo R R Shoulder Service Hospital F. Miulli, Acquaviva delle fonti, BA, Italy, - - 2014
Late sequelae of septic arthritis of the glenohumeral joint are very rare and represent a potentially devastating condition that can result in irreversible changes at the level of joint and surrounding soft tissues. Between January 2001 and December 2010, ten patients were treated at our institution for late sequelae of ...
Collinge Cory C 1Director of Orthopedic Trauma, Texas Health Harris Methodist Hospital, Staff physician John Peter Smith Orthopedic Surgery Residency, Fort Worth, TX, 2Orthopedic Trauma Clinical Nurse Specialist, Texas Health Harris Methodist Hospital, Fort Worth, TX 3Pharmacoeconomist, VA North Texas Health Care System, Dallas, TX 4Orthopedic Traumatologist, Texas Health Harris Methodist Fort Worth Hospital, Fort Worth, - - 2014
Administration of early and appropriate antibiotic in treating patients with open fractures is an important early factor in preventing infection and optimizing outcomes. The purpose of this study is to evaluate the effects of an orthopedic trauma performance improvement program directed at early antibiotic administration for open fracture patients at ...
Soong Poh Luon PL Department of Cranio-Maxillofacial Surgery, Inselspital, Bern University Hospital, and University of Bern, Switzerland; Department of Oral and Maxillofacial Surgery, National Dental Centre Singapore, - - 2014
The aim of this study was to evaluate the difference between the effect of a 5-day and a 1-day postoperative course of antibiotics on the incidence of infection after midfacial fractures. A total of 98 patients with displaced Le Fort or zygomatic fractures that required operation were randomly assigned into ...
Oomens M A E M MA Department of Oral and Maxillofacial Surgery/Oral Pathology, VU University Medical Centre/Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam, Netherlands. Electronic address: - - 2014
There is no consensus on the use of antibiotic prophylaxis in orthognathic surgery to prevent infections. A systematic review of randomized controlled trials investigating the efficacy of antibiotic prophylaxis was performed to make evidence-based recommendations. A search of Embase, Ovid Medline, and Cochrane databases (1966-November 2012) was conducted and the ...
Mottini Matthias M From the Department of Cranio-Maxillofacial Surgery (M.M., R.W., P.L.S., O.L., K.N., B.S.), Inselspital University Hospital Bern, Switzerland; and Department of Oral and Maxillofacial Surgery (P.L.S.), National Dental Centre, - - 2014
The goal of this study was to evaluate the influence of the duration of postoperative antibiotics (1 day vs. ≥ 5 days) on wound infections following surgical treatment of facial fractures. Three hundred thirty-nine patient case histories with a total of 498 fractures were reviewed retrospectively with regard to infections ...
Mohan Rosh Radhika RR Department of Periodontics, The Oxford Dental College, Bangalore, Karnataka, - - 2014
Aim of this randomly controlled clinical study was to evaluate the role of antibiotics to prevent postoperative complications after routine periodontal surgery and also to determine whether their administration improved the surgical outcome. Forty-five systemically healthy patients with moderate to severe chronic periodontitis requiring flap surgery were enrolled in the ...
Collins Courtney E CE Center for Outcomes Research Surgical Research Scholars Program, Department of Surgery, University of Massachusetts, Worcester, MA. Electronic address: - - 2014
The incidence of community-acquired Clostridium difficile (CACD) is increasing in the United States. Many CACD infections occur in the elderly, who are predisposed to poor outcomes. We aimed to describe the epidemiology and outcomes of CACD in a nationally representative sample of Medicare beneficiaries. We queried a 5% random sample ...
Edgeworth Jonathan D JD Centre for Clinical Infection and Diagnostic Research (CIDR), Department of Infectious Diseases, Kings College London and Guy's and St Thomas' NHS Foundation Trust, St Thomas' Hospital, Westminster Bridge Road, London SE1 7EH, - - 2014
To determine long-term adherence to a 5 day antibiotic course guideline for treating intensive care unit (ICU)-acquired Gram-negative bacteria (GNB) infections. Descriptive analysis of patient-level data on all GNB-active antibiotics prescribed from day 3 and all GNB identified in clinical samples in 5350 patients admitted to a 30 bed general ...
Oh Choon Chiat CC Department of Dermatology, Singapore General Hospital, Singapore. Electronic address: - - 2014
A significant proportion of patients who have had a first episode of erysipelas or uncomplicated cellulitis will subsequently develop a recurrence. There is disagreement about how effective antibiotic prophylaxis is for preventing recurrent cellulitis. To determine if antibiotic prophylaxis is effective in preventing recurrent cellulitis compared to no prophylaxis using ...
Masada Tetsuya T Department of Radiology (T.M., T.T., H.N., K.K.), Nara Medical University, - - 2014
To compare the efficacy, complications, and inflammatory levels in partial splenic embolization (PSE) with coils or gelatin sponge (GS) particles with or without intraarterial antibiotic agents. Forty-four patients with hypersplenism treated by PSE were assessed. GS particles were used in 31 patients, and coils were used in 13 patients. In ...
Clark Nathan P NP Department of Clinical Pharmacy, Kaiser Permanente Colorado, Aurora 2Department of Clinical Pharmacy, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, - - 2014
IMPORTANCE The effect of antibiotic coadministration on the international normalized ratio (INR) in a relatively stable, real-world warfarin population has not been adequately described. Case reports and studies of healthy volunteers do not account for the potential contribution of acute illness to INR variability. OBJECTIVE To compare the risk of ...
Little Paul P Primary Care and Population Sciences Division, University of Southampton, Southampton, UK. Electronic address: - - 2014
Data from trials suggest that antibiotics reduce the risk of complications of sore throat by at least 50%, but few trials for complications have been done in modern settings, and datasets of delayed antibiotic prescription are underpowered. Observational evidence is important in view of poor compliance with antibiotic treatment outside ...
Zhang Zi Z Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, - - 2014
Despite their widespread use, antibiotics have not been shown to improve chronic rhinosinusitis (CRS) outcomes. We aimed to determine whether culture-inappropriate postoperative antibiotic therapy was associated with less quality-of-life (QOL) improvement following functional endoscopic sinus surgery (FESS). This retrospective cohort study recruited 376 adult CRS patients undergoing FESS between October ...
Zhang Yi Y From the Shanghai Ninth People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, - - 2014
There is no consensus with regard to antibiotic prophylaxis usage in clean and clean-contaminated plastic and reconstructive surgery. This meta-analysis sought to assess the efficacy and safety of antibiotic prophylaxis and to determine appropriate duration of prophylaxis. An English language literature search was conducted using PubMed and the Cochrane Collaboration ...
Little Paul P University of Southampton, Aldermoor Health Centre, Southampton SO16 5ST, - - 2014
To estimate the effectiveness of different strategies involving delayed antibiotic prescription for acute respiratory tract infections. Open, pragmatic, parallel group, factorial, randomised controlled trial. Primary care in the United Kingdom. 889 patients aged 3 years and over with acute respiratory tract infection, recruited between 3 March 2010 and 28 March ...
Huang Ting-Shuo TS The Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan; Division of General Surgery, Department of Surgery, Chang Gung Memorial Hospital, Keelung Branch, Keelung, - - 2014
Procalcitonin (PCT)-based algorithms have been used to guide antibiotic therapy in several clinical settings. However, evidence supporting PCT-based algorithms for secondary peritonitis after emergency surgery is scanty. In this study, we aimed to investigate whether a PCT-based algorithm could safely reduce antibiotic exposure in this population. From April 2012 to ...
Wright Alissa Jade AJ Department of Medicine, Division of Infectious Disease, University of British Columbia, Vancouver General - - 2014
To determine whether utilization of moxifloxacin, a broad-spectrum fluoroquinolone antibiotic, has changed since its addition to the British Columbia provincial formulary in 2009 and to determine whether utilization was guideline concordant. BC PharmaNet prescriptions for moxifloxacin from 2001 to 2010 were anonymously linked to associated Medical Services Plan fee-for-service practitioner ...
Bosmans Judith E JE Department of Health Sciences and EMGO Institute for Health and Care Research, Faculty of Earth and Life Sciences, VU University Amsterdam, Amsterdam, The - - 2014
Urinary tract infections (UTIs) are common and result in an enormous economic burden. The increasing prevalence of antibiotic-resistant microorganisms has stimulated interest in non-antibiotic agents to prevent UTIs. To evaluate the cost-effectiveness of cranberry prophylaxis compared to antibiotic prophylaxis with trimethoprim-sulfamethoxazole (TMP-SMX) over a 12 month period in premenopausal women ...
Gupta M - - 2014
To evaluate the usefulness of antibiotic+steroid irrigation of the middle ear in patients with otitis media with small perforation and pulsatile discharge. A prospective, randomised, evaluator-blinded study was carried at a single tertiary care centre over eight years, looking at 100 patients with chronic suppurative otitis media involving small tympanic ...
Rehmani Rifat S RS Department of Emergency Medicine, King Abdulaziz Hospital, P.O. Box 2477, Al-Ahsa, Saudi - - 2014
Background. The objective of this study is to evaluate the impact of an ED sepsis protocol on the time to antibiotics for emergency department (ED) patients with severe sepsis. Methods. Quasiexperimental prospective study was conducted at the emergency department. Consecutive patients with severe sepsis were included before and after the ...
Wang Shou Zhen SZ Surgical Intensive Care Unit, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, - - 2014
Daptomycin, a cyclic lipopeptide that exhibits rapid, concentration-dependent bactericidal activity in vitro against a broad spectrum of Gram-positive pathogens, has now, since 2003, been approved in more than 70 countries and regions to treat skin and soft-tissue infections (SSTIs). The purpose of this meta-analysis was to compare the safety and ...
Barrett Ryan J RJ Providence Hospital and Medical Centers, Department of Neurological Surgery, Southfield, MI, - - 2014
To evaluate the feasibility of this novel surgical approach for treatment of cervical discitis and vertebral osteomyelitis. MATERIAL and This is a report of two patients who underwent anterior cervical decompression for discitis and vertebral osteomyelitis (DVO) with cervical spine reconstruction with polymethylmethacrylate impregnated with antibiotics (AI-PMMA). Both patients had ...
Janbakhsh Alireza A Department of Infectious Diseases and Tropical Medicine, Kermanshah University of Medical Sciences, Kermanshah. - - 2013
A 70 years old man was referred to our center with bilateral knee arthritis following intra-articular petrol injection. As a result of the previous use of antibiotics, gram stain and culture were negative. Patient was diagnosed with septic arthritis and was treated by antibiotics and drainage. After two years, his ...
Jettoo P P Department of Trauma and Orthopaedics, Sunderland Royal Hospital, Sunderland, United - - 2013
PURPOSE. To compare a 3-dose cefuroxime regimen with a single-dose gentamicin and amoxicillin regimen as antibiotic prophylaxis for hip hemiarthroplasty in terms of microbiological outcome. METHODS. Records of 2 matched groups of patients who underwent hip hemiarthroplasty for femoral neck fractures were reviewed. 29 men and 84 women (mean age, ...
Frumenzio Emanuela E Clinica Urologica e Andrologica di Perugia, Università degli Studi di Perugia. - - 2013
Objective: Aim of this study is to evaluate the efficacy of a phytotherapic which includes Solidago, Orthosiphon and Birch extract (Cistimev®) in association with antibiotic prophylaxis in female patients affected by recurrent urinary tract infections (UTIr). Materials and methods: Patients affected by UTIr older than 18 years started a 3-months ...
Ijarotimi A O AO Department of Obstetrics, Gynaecology and Perinatology, Obafemi Awolowo University, - - 2013
Aims and Objectives: This study was to determine any significant difference between the incidence of infectious morbidity with the use of a 24 hour antibiotics regimen compared to a 7-day course of antibiotics following elective caesarean section using a cheap and easily available combination of Ampicillin/Cloxacillin and Metronidazole. Patients and ...
Staykova Toni - - 2013
The use of prophylactic antibiotics to reduce the frequency and severity of acute exacerbations of chronic bronchitis is controversial. To determine if prophylactic antibiotics reduce the frequency of exacerbations and/or days of disability in subjects with chronic bronchitis. We searched the Cochrane Airways Group trials register and the bibliographies of ...
Briggs Simon - - 2013
Background: In the 1970s, there were 2 reports of a late-onset adverse reaction during bolus infusions of benzyl penicillin, characterized by short-lived symptoms, most commonly abdominal pain. The mechanism is not known. We set out to further characterize this reaction. Methods: We conducted a prospective observational study of all adult ...
Wang Chih-Hung - - 2013
Few studies have followed patients who received antibiotic treatment for acute cholecystitis (AC). The present retrospective study investigated recurrence rates of AC and analyzed factors associated with recurrence after antibiotic treatment in adult AC patients. We analyzed patients treated with antibiotics for AC between October 1, 2004, and November 30, ...
Roos D - - 2013
Studies on selective decontamination of the digestive tract (SDD) in elective gastrointestinal surgery have shown decreased rates of postoperative infection and anastomotic leakage. However, the prophylactic use of perioperative SDD in elective gastrointestinal surgery is not generally accepted. A systematic review of randomized clinical trials (RCTs) was conducted to compare ...
Tamkus Arvydas A - - 2013
False-positive loss of transcranial electrical motor evoked potentials (TCe-MEPs) limits the efficacy of motor tract monitoring during spine surgery. Although total intravenous anesthesia (TIVA) is widely regarded as the optimal regimen for TCe-MEPs, inhalational anesthesia is an alternative regimen. To compare the rates of false-positive TCe-MEPs during spine surgery for ...
Storey Philip - - 2013
To compare the incidence of endophthalmitis after intravitreal injection with and without topical postinjection antibiotic prophylaxis. Retrospective case-control study. All patients treated with intravitreal injection of ranibizumab, bevacizumab, or aflibercept for a variety of retinal vascular diseases at a single, large retina practice between January 1, 2009, and October 1, ...
Hsieh Cheng-Hsing - - 2013
To compare the efficacy of prophylactic antibiotics in reduction of post-surgical infections in patients undergoing ureterorenoscopic lithotripsy (URSL). The study is a double-blind, prospective, randomized controlled trial. Between 2009 and 2012, 212 patients with preoperative sterile urine undergoing URSL were randomly allocated by the randomization ratio of 1:1:1:1 to receive ...
Mahajan Sminil N - - 2013
To evaluate the role of ertapenem versus other standard antibiotic prophylaxis in patients with cancer undergoing intra-abdominal surgery. Our study was a retrospective cohort study consisting 615 patients who underwent intra-abdominal surgery at our institution between January 2007 and December 2010. The groups were divided among patients who received ertapenem ...
Abzug Mark J - - 2013
Bacteria can be recovered from paranasal sinuses in the majority of patients given the diagnosis of acute bacterial sinusitis (ABS), and bacteriologic cure can be achieved with appropriate antibiotic treatment. The critical question is whether bacteriologic cure correlates with meaningful clinical endpoints such as clinical improvement, reduction in recurrent disease, ...
Oshima Tsutomu - - 2013
The usefulness of preoperative oral antibiotics for the prevention of surgical site infection in elective colorectal surgery remains controversial. This study aimed to investigate the effects of oral antimicrobial prophylaxis in addition to intravenous antimicrobial prophylaxis on patients with ulcerative colitis undergoing restorative proctocolectomy. This study was a randomized, nonblinded, ...
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