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Lee Young H YH Department of Dermatology, Division of Health Services Research. Electronic address: - - 2014
Duration of oral antibiotic therapy in acne has not been widely studied. Recent guidelines suggest it should be limited to 3 to 6 months. We sought to compare the duration of oral antibiotic use with recent guidelines and determine the potential cost-savings related to shortened durations. This is a retrospective ...
Mazaki Takero T Department of Surgery, Nihon University School of Medicine, Tokyo, Japan. Electronic address: - - 2014
The efficacy of antibiotic prophylaxis for the prevention of surgical-site infection (SSI) after open tension-free inguinal hernia repair remains controversial. A double-blind, randomized, placebo-controlled trial was conducted. Patients who underwent elective open mesh-plug hernia repair were eligible for randomization. In the antibiotic prophylaxis group, 1.0 g cefazolin was intravenously administrated ...
Gyorfi Justin R JR Division of Urology, Penn State Milton S. Hershey Medical Center, 500 University Drive, H055, Hershey, PA, 17033-0850, - - 2014
The purpose of the study was to evaluate whether a peri-procedural povidone-iodine rectal preparation (PIRP) prior to transrectal ultrasound-guided prostate needle biopsy (TRUS PNB) can reduce microorganism colony counts and infectious complications. Our institutional TRUS PNB database was reviewed to identify infectious post-biopsy complications (defined as fever >38.5 °C with positive culture). ...
Garofalo R R Shoulder Service Hospital F. Miulli, Acquaviva delle fonti, BA, Italy, - - 2014
Late sequelae of septic arthritis of the glenohumeral joint are very rare and represent a potentially devastating condition that can result in irreversible changes at the level of joint and surrounding soft tissues. Between January 2001 and December 2010, ten patients were treated at our institution for late sequelae of ...
Collinge Cory C 1Director of Orthopedic Trauma, Texas Health Harris Methodist Hospital, Staff physician John Peter Smith Orthopedic Surgery Residency, Fort Worth, TX, 2Orthopedic Trauma Clinical Nurse Specialist, Texas Health Harris Methodist Hospital, Fort Worth, TX 3Pharmacoeconomist, VA North Texas Health Care System, Dallas, TX 4Orthopedic Traumatologist, Texas Health Harris Methodist Fort Worth Hospital, Fort Worth, - - 2014
Administration of early and appropriate antibiotic in treating patients with open fractures is an important early factor in preventing infection and optimizing outcomes. The purpose of this study is to evaluate the effects of an orthopedic trauma performance improvement program directed at early antibiotic administration for open fracture patients at ...
Soong Poh Luon PL Department of Cranio-Maxillofacial Surgery, Inselspital, Bern University Hospital, and University of Bern, Switzerland; Department of Oral and Maxillofacial Surgery, National Dental Centre Singapore, - - 2014
The aim of this study was to evaluate the difference between the effect of a 5-day and a 1-day postoperative course of antibiotics on the incidence of infection after midfacial fractures. A total of 98 patients with displaced Le Fort or zygomatic fractures that required operation were randomly assigned into ...
Oomens M A E M MA Department of Oral and Maxillofacial Surgery/Oral Pathology, VU University Medical Centre/Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam, Netherlands. Electronic address: - - 2014
There is no consensus on the use of antibiotic prophylaxis in orthognathic surgery to prevent infections. A systematic review of randomized controlled trials investigating the efficacy of antibiotic prophylaxis was performed to make evidence-based recommendations. A search of Embase, Ovid Medline, and Cochrane databases (1966-November 2012) was conducted and the ...
Mottini Matthias M From the Department of Cranio-Maxillofacial Surgery (M.M., R.W., P.L.S., O.L., K.N., B.S.), Inselspital University Hospital Bern, Switzerland; and Department of Oral and Maxillofacial Surgery (P.L.S.), National Dental Centre, - - 2014
The goal of this study was to evaluate the influence of the duration of postoperative antibiotics (1 day vs. ≥ 5 days) on wound infections following surgical treatment of facial fractures. Three hundred thirty-nine patient case histories with a total of 498 fractures were reviewed retrospectively with regard to infections ...
Edgeworth Jonathan D JD Centre for Clinical Infection and Diagnostic Research (CIDR), Department of Infectious Diseases, Kings College London and Guy's and St Thomas' NHS Foundation Trust, St Thomas' Hospital, Westminster Bridge Road, London SE1 7EH, - - 2014
To determine long-term adherence to a 5 day antibiotic course guideline for treating intensive care unit (ICU)-acquired Gram-negative bacteria (GNB) infections. Descriptive analysis of patient-level data on all GNB-active antibiotics prescribed from day 3 and all GNB identified in clinical samples in 5350 patients admitted to a 30 bed general ...
Oh Choon Chiat CC Department of Dermatology, Singapore General Hospital, Singapore. Electronic address: - - 2014
A significant proportion of patients who have had a first episode of erysipelas or uncomplicated cellulitis will subsequently develop a recurrence. There is disagreement about how effective antibiotic prophylaxis is for preventing recurrent cellulitis. To determine if antibiotic prophylaxis is effective in preventing recurrent cellulitis compared to no prophylaxis using ...
Masada Tetsuya T Department of Radiology (T.M., T.T., H.N., K.K.), Nara Medical University, - - 2014
To compare the efficacy, complications, and inflammatory levels in partial splenic embolization (PSE) with coils or gelatin sponge (GS) particles with or without intraarterial antibiotic agents. Forty-four patients with hypersplenism treated by PSE were assessed. GS particles were used in 31 patients, and coils were used in 13 patients. In ...
Clark Nathan P NP Department of Clinical Pharmacy, Kaiser Permanente Colorado, Aurora 2Department of Clinical Pharmacy, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, - - 2014
IMPORTANCE The effect of antibiotic coadministration on the international normalized ratio (INR) in a relatively stable, real-world warfarin population has not been adequately described. Case reports and studies of healthy volunteers do not account for the potential contribution of acute illness to INR variability. OBJECTIVE To compare the risk of ...
Little Paul P Primary Care and Population Sciences Division, University of Southampton, Southampton, UK. Electronic address: - - 2014
Data from trials suggest that antibiotics reduce the risk of complications of sore throat by at least 50%, but few trials for complications have been done in modern settings, and datasets of delayed antibiotic prescription are underpowered. Observational evidence is important in view of poor compliance with antibiotic treatment outside ...
Zhang Zi Z Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, - - 2014
Despite their widespread use, antibiotics have not been shown to improve chronic rhinosinusitis (CRS) outcomes. We aimed to determine whether culture-inappropriate postoperative antibiotic therapy was associated with less quality-of-life (QOL) improvement following functional endoscopic sinus surgery (FESS). This retrospective cohort study recruited 376 adult CRS patients undergoing FESS between October ...
Zhang Yi Y From the Shanghai Ninth People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, - - 2014
There is no consensus with regard to antibiotic prophylaxis usage in clean and clean-contaminated plastic and reconstructive surgery. This meta-analysis sought to assess the efficacy and safety of antibiotic prophylaxis and to determine appropriate duration of prophylaxis. An English language literature search was conducted using PubMed and the Cochrane Collaboration ...
Little Paul P University of Southampton, Aldermoor Health Centre, Southampton SO16 5ST, - - 2014
To estimate the effectiveness of different strategies involving delayed antibiotic prescription for acute respiratory tract infections. Open, pragmatic, parallel group, factorial, randomised controlled trial. Primary care in the United Kingdom. 889 patients aged 3 years and over with acute respiratory tract infection, recruited between 3 March 2010 and 28 March ...
Huang Ting-Shuo TS The Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan; Division of General Surgery, Department of Surgery, Chang Gung Memorial Hospital, Keelung Branch, Keelung, - - 2014
Procalcitonin (PCT)-based algorithms have been used to guide antibiotic therapy in several clinical settings. However, evidence supporting PCT-based algorithms for secondary peritonitis after emergency surgery is scanty. In this study, we aimed to investigate whether a PCT-based algorithm could safely reduce antibiotic exposure in this population. From April 2012 to ...
Wright Alissa Jade AJ Department of Medicine, Division of Infectious Disease, University of British Columbia, Vancouver General - - 2014
To determine whether utilization of moxifloxacin, a broad-spectrum fluoroquinolone antibiotic, has changed since its addition to the British Columbia provincial formulary in 2009 and to determine whether utilization was guideline concordant. BC PharmaNet prescriptions for moxifloxacin from 2001 to 2010 were anonymously linked to associated Medical Services Plan fee-for-service practitioner ...
Bosmans Judith E JE Department of Health Sciences and EMGO Institute for Health and Care Research, Faculty of Earth and Life Sciences, VU University Amsterdam, Amsterdam, The - - 2014
Urinary tract infections (UTIs) are common and result in an enormous economic burden. The increasing prevalence of antibiotic-resistant microorganisms has stimulated interest in non-antibiotic agents to prevent UTIs. To evaluate the cost-effectiveness of cranberry prophylaxis compared to antibiotic prophylaxis with trimethoprim-sulfamethoxazole (TMP-SMX) over a 12 month period in premenopausal women ...
Jettoo P P Department of Trauma and Orthopaedics, Sunderland Royal Hospital, Sunderland, United - - 2013
PURPOSE. To compare a 3-dose cefuroxime regimen with a single-dose gentamicin and amoxicillin regimen as antibiotic prophylaxis for hip hemiarthroplasty in terms of microbiological outcome. METHODS. Records of 2 matched groups of patients who underwent hip hemiarthroplasty for femoral neck fractures were reviewed. 29 men and 84 women (mean age, ...
Frumenzio Emanuela E Clinica Urologica e Andrologica di Perugia, Università degli Studi di Perugia. - - 2013
Objective: Aim of this study is to evaluate the efficacy of a phytotherapic which includes Solidago, Orthosiphon and Birch extract (Cistimev®) in association with antibiotic prophylaxis in female patients affected by recurrent urinary tract infections (UTIr). Materials and methods: Patients affected by UTIr older than 18 years started a 3-months ...
Ijarotimi A O AO Department of Obstetrics, Gynaecology and Perinatology, Obafemi Awolowo University, - - 2013
Aims and Objectives: This study was to determine any significant difference between the incidence of infectious morbidity with the use of a 24 hour antibiotics regimen compared to a 7-day course of antibiotics following elective caesarean section using a cheap and easily available combination of Ampicillin/Cloxacillin and Metronidazole. Patients and ...
Staykova Toni - - 2013
The use of prophylactic antibiotics to reduce the frequency and severity of acute exacerbations of chronic bronchitis is controversial. To determine if prophylactic antibiotics reduce the frequency of exacerbations and/or days of disability in subjects with chronic bronchitis. We searched the Cochrane Airways Group trials register and the bibliographies of ...
Briggs Simon - - 2013
Background: In the 1970s, there were 2 reports of a late-onset adverse reaction during bolus infusions of benzyl penicillin, characterized by short-lived symptoms, most commonly abdominal pain. The mechanism is not known. We set out to further characterize this reaction. Methods: We conducted a prospective observational study of all adult ...
Wang Chih-Hung - - 2013
Few studies have followed patients who received antibiotic treatment for acute cholecystitis (AC). The present retrospective study investigated recurrence rates of AC and analyzed factors associated with recurrence after antibiotic treatment in adult AC patients. We analyzed patients treated with antibiotics for AC between October 1, 2004, and November 30, ...
Roos D - - 2013
Studies on selective decontamination of the digestive tract (SDD) in elective gastrointestinal surgery have shown decreased rates of postoperative infection and anastomotic leakage. However, the prophylactic use of perioperative SDD in elective gastrointestinal surgery is not generally accepted. A systematic review of randomized clinical trials (RCTs) was conducted to compare ...
Tamkus Arvydas A - - 2013
False-positive loss of transcranial electrical motor evoked potentials (TCe-MEPs) limits the efficacy of motor tract monitoring during spine surgery. Although total intravenous anesthesia (TIVA) is widely regarded as the optimal regimen for TCe-MEPs, inhalational anesthesia is an alternative regimen. To compare the rates of false-positive TCe-MEPs during spine surgery for ...
Storey Philip - - 2013
To compare the incidence of endophthalmitis after intravitreal injection with and without topical postinjection antibiotic prophylaxis. Retrospective case-control study. All patients treated with intravitreal injection of ranibizumab, bevacizumab, or aflibercept for a variety of retinal vascular diseases at a single, large retina practice between January 1, 2009, and October 1, ...
Hsieh Cheng-Hsing - - 2013
To compare the efficacy of prophylactic antibiotics in reduction of post-surgical infections in patients undergoing ureterorenoscopic lithotripsy (URSL). The study is a double-blind, prospective, randomized controlled trial. Between 2009 and 2012, 212 patients with preoperative sterile urine undergoing URSL were randomly allocated by the randomization ratio of 1:1:1:1 to receive ...
Mahajan Sminil N - - 2013
To evaluate the role of ertapenem versus other standard antibiotic prophylaxis in patients with cancer undergoing intra-abdominal surgery. Our study was a retrospective cohort study consisting 615 patients who underwent intra-abdominal surgery at our institution between January 2007 and December 2010. The groups were divided among patients who received ertapenem ...
Abzug Mark J - - 2013
Bacteria can be recovered from paranasal sinuses in the majority of patients given the diagnosis of acute bacterial sinusitis (ABS), and bacteriologic cure can be achieved with appropriate antibiotic treatment. The critical question is whether bacteriologic cure correlates with meaningful clinical endpoints such as clinical improvement, reduction in recurrent disease, ...
Oshima Tsutomu - - 2013
The usefulness of preoperative oral antibiotics for the prevention of surgical site infection in elective colorectal surgery remains controversial. This study aimed to investigate the effects of oral antimicrobial prophylaxis in addition to intravenous antimicrobial prophylaxis on patients with ulcerative colitis undergoing restorative proctocolectomy. This study was a randomized, nonblinded, ...
Cherian Paul - - 2013
The optimal method of reducing the risk of surgical site infection (SSI) after dermatologic surgery is unclear. Empiric, preoperative antibiotic use is common practice but lacks supporting evidence for its efficacy in preventing SSI. Risk stratification for patients at high risk of postoperative SSI based on a nasal swab is a viable strategy ...
Daskalakis K - - 2013
The aim of this study was to review the literature regarding the use of pre- and/or postoperative antibiotics in the management of appendicitis, using data obtained from PubMed and the Cochrane Library. A literature search was conducted using the terms "appendicitis" combined with "antibiotics." Studies were selected based on relevance ...
Mazaki Takero - - 2013
Efficacy of antibiotic prophylaxis for the prevention of surgical site infection (SSI) after open tension-free hernia repair remains controversial. In light of additional data, the aim of this study was to determine whether antibiotic prophylaxis reduces SSI after hernia repair. We conducted a systematic review and meta-analysis to identify randomized ...
Schaller Benoit - - 2013
The aim of this study was to evaluate the difference between a 5-day and a 1-day postoperative course of antibiotic on the incidence of infection after mandibular fractures involving the alveolus. Sixty-two patients with fractures of the mandible involving the dentoalveolar region were randomly assigned to 2 groups, both of ...
Torres Fernando A - - 2013
Although more than half of the cases of pneumonia in children can be due to virus, most of them receive antibiotic treatment. A previously published clinical prediction rule bacterial pneumonia score (BPS) allows the identification of children with pneumonia who do not require antibiotics, but its impact has not been ...
Bohm Eric - - 2013
There is considerable debate about whether antibiotic-loaded bone cement should be used for fixation of TKAs. While antibiotics offer the theoretical benefit of lowering early revision due to infection, they may weaken the cement and thus increase the likelihood of aseptic loosening, perhaps resulting in a higher revision rate. We ...
Gower Emily W - - 2013
Endophthalmitis is a severe inflammation of the anterior and/or posterior chambers of the eye that may be sterile or associated with infection. It is a potentially vision-threatening complication of cataract surgery. Prophylactic measures for endophthalmitis are targeted against various sources of infection. The objective of this review was to evaluate ...
James Gareth Dean Russell - - 2013
Exacerbations of chronic obstructive pulmonary disease (COPD) are a burden to patients and impose a major cost on health services. Long-term antibiotic therapy may prevent exacerbations, but at present it is not recommended by management guidelines. To identify the type and prevalence of long-term oral antibiotic treatments prescribed to patients ...
Lusardi Gail - - 2013
Urinary tract infections account for about 40% of hospital-acquired (nosocomial) infections, and about 80% of urinary tract infections acquired in hospital are associated with urinary catheters. To determine if certain antibiotic prophylaxes are better than others in terms of prevention of urinary tract infections, complications, quality of life and cost-effectiveness ...
Wijewickrama Rohan C RC St. Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA 02135, - - 2013
Postoperative infection remains a significant comorbidity of endoscopic sinus surgery (ESS) delayed healing, synechia formation, etc. The objective of this study was to compare the incidence of postoperative infection after ESS in patients receiving conventional postoperative oral antibiotic prophylaxis versus a synthetic bioabsorbable antibiotic-soaked nasal sponge used in the middle ...
Yu Tzu-Chieh - - 2013
Introduction Postoperative antibiotics complement surgery in managing childhood-complicated appendicitis. However, there is limited evidence to guide clinicians on appropriate duration of therapy. A comparison cohort study was performed to determine whether tailoring duration of inpatient intravenous (IV) antibiotic therapy to patient response, assessed using a set of clinical criteria, leads ...
Giordano Salvatore - - 2013
Background:Antibacterial lavage with topical antibiotics may reduce the occurrence of capsular contracture (CC) in breast augmentation.Objectives:The authors investigate the efficacy of povidone-iodine combined with antibiotic irrigation in reducing the CC rate.Methods:The charts of 333 consecutive women who underwent cosmetic breast augmentation during 2 different periods (group A: 2004-2009, n = ...
Ein Sigmund H - - 2013
We conducted a 3-decade clinical review of prophylaxis for wound infection and postoperative intra-abdominal abscess after open appendectomy for pediatric ruptured appendicitis. We reviewed the charts of patients with ruptured appendicitis who underwent open appendectomy performed by the same pediatric surgeon at the Hospital for Sick Children, Toronto, Canada, between ...
Singer Adam J - - 2013
BACKGROUND: Over the last decade, there has been a significant increase in the number of cutaneous abscesses. While there is general agreement that abscesses should be treated with incision and drainage, it is unclear whether systemic antibiotics should be routinely prescribed. OBJECTIVE: To evaluate whether systemic antibiotics, when compared with ...
Fay Aaron - - 2013
PURPOSE:: To investigate the necessity and usefulness of prophylactic postoperative antibiotics in patients undergoing enucleation or ocular evisceration. METHODS:: A retrospective, multicenter, comparative case series was designed. After obtaining Institutional Review Board authorization, a medical records' review was conducted. Demographics, indication for surgery, surgical technique, postoperative antibiotic dosing, and postoperative ...
Jia Xin - - 2013
Purpose : To report early and midterm outcomes after open or endovascular repair of primary mycotic aortic aneurysms treated over a 10-year period in a single center. Methods : The records of all 12 patients (10 men; 72.9 years, range 59-83) treated for primary mycotic aortic aneurysms from September 2001 ...
Vallés Jordi J Critical Care Center, Hospital Sabadell, Consorci Hospitalari Universitari Parc Taulí, CIBER Enfermedades Respiratorias, Sabadell, Spain. - - 2013
Comatose patients present a high risk of early-onset ventilator-associated pneumonia (EO-VAP) for which antibiotic prophylaxis has been proposed. Comatose patients were studied to evaluate the efficacy of a single-dose of antibiotic prophylaxis at intubation against EO-VAP. A prospective cohort of comatose patients (Glasgow Coma Score ≤ 8) who were admitted ...
Pushker Neelam - - 2013
PURPOSE: To evaluate the role of oral corticosteroids as an anti-inflammatory adjunct in the treatment of orbital cellulitis. DESIGN: Prospective, comparative, single-masked, interventional clinical study. METHODS: setting: Tertiary eye care center (All India Institute of Medical Sciences). study population: Patients with acute onset (within 14 days) of orbital cellulitis with or ...
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