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Results 151 - 200 of 925
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Catalano Peter J - - 2011
Objective. To evaluate the safety and tolerability of a novel, fully synthetic, poly-urethane middle meatal dressing after endoscopic sinus surgery (ESS). Study Design. Case series with planned data collection. Setting. Tertiary care medical facility. Subjects and Methods. In total, 104 patients with medically refractory chronic rhinosinusitis were treated with patient-appropriate ...
Reddy Vivek Y - - 2011
Background- The Watchman Left Atrial Appendage System for Embolic Protection in Patients With AF (PROTECT AF) randomized trial compared left atrial appendage closure against warfarin in atrial fibrillation (AF) patients with CHADS(2) ≥1. Although the study met the primary efficacy end point of being noninferior to warfarin therapy for the ...
Chuang Yin-Ching - - 2011
To compare the monotherapy of tigecycline with vancomycin-aztreonam in hospitalized patients from India and Taiwan with complicated skin and skin structure infections (cSSSIs). Safety and efficacy data were analyzed for Indian (n = 86) and Taiwanese (n = 41) patients hospitalized with cSSSIs who participated in two international Phase 3, randomized, double-blind studies. Patients ...
Talamonti Marina - - 2011
Conventional systemic therapies for psoriasis are associated with serious toxicities that can limit long-term use. In recent years, biological therapies have offered the possibility of long-term therapy with improved safety and efficacy for the treatment of psoriasis. Biological therapies can be classified into three categories: the T-cell modulating agents (alefacept ...
Kim Chung-Hoon - - 2011
BACKGROUND Myolysis is one of the procedures that is claimed to provide significant improvement in myoma status without hysterectomy. Myolysis procedures have been generally performed via laparoscopy, and there are limited data on transvaginal radiofrequency (RF) myolysis. This study investigated the feasibility, efficacy and safety of transvaginal ultrasound-guided RF myolysis. ...
Chhetri Dinesh K - - 2011
OBJECTIVES: This study evaluated the safety and effectiveness of injection of autologous fibroblasts into the lamina propria layer to treat vocal fold scarring. STUDY DESIGN: A prospective, open-label, single arm, pilot study at a single tertiary care center. METHODS: Autologous fibroblasts were expanded in cell culture from punch biopsies of ...
Stauss-Grabo M - - 2011
The only saponin drug currently prescribed in any significant amount in monotherapy medicines is ivy. This post-marketing surveillance study (PMSS) aimed at investigating the tolerability and safety of film-coated tablets containing ivy leaves dry extract (extracting medium: ethanol 30%, DER 5-7.5:1 [Prospan(®) Cough Tablets]) under practice conditions. Adults and children ...
Nie Hai - - 2011
To evaluate the efficacy and safety of surgery for lumbar disc herniation in patients aged 80 or older. MATERIAL and Operative time (OT), intraoperative estimated blood loss (EBL), length of hospital stay (LOS), and complication rate (CR) were used to assess safety of surgery. The Visual Analog Scale (VAS), the ...
Bal Serpil - - 2011
The aim of this study was to compare anatomic and functional improvements in zone II and zone V flexor tendon injuries and to determine the effect of injury level on disability. Seventeen patients (53 digits) with zone V and 14 patients (25 digits) with repaired zone II flexor tendon injuries ...
Harbrecht U - - 2011
Vitamin-K-antagonists (VKA) and heparins have been complementary anticoagulants for prevention and treatment of thrombosis for almost 70 years. In contrast to heparins, VKA have not been modified pharmacologically, however treatment surveillance has improved by introducing INR and self-monitoring/management. Disclosure of the molecular basis of interaction with VKORC1, the target enzyme ...
Fogarty Patrick F - - 2011
Since the introduction of replacement coagulation factor infusions for the treatment of hemophilia in the 1970s and subsequent improvements in the safety profile of available factor VIII (FVIII) and factor IX (FIX) concentrates, mortality among patients with hemophilia has improved considerably and now parallels that of the noncoagulopathic population in ...
Sturm Lana P - - 2011
Background:  Dermal fillers are gaining popularity for rapid aesthetic improvement. Long-term efficacy and safety have not been well documented. The aim of this systematic review was to assess the safety and efficacy of injectable dermal fillers compared with other facial augmentation techniques for the management of age-related lines and wrinkles. ...
Brunasso Alexandra M G - - 2011
Studies comparing the safety and tolerability of biological therapies for psoriasis in the long-term and in daily clinical practice are lacking. Most published studies are of selected patients with short-term (3-6 months) follow-up. We performed a retrospective cohort study of 103 patients in order to describe the frequency and the ...
Kesman Thomas J - - 2011
The contribution provided by the popliteus tendon in patients undergoing TKA is poorly defined. Some authors believe the popliteus tendon is essential to a well-functioning arthroplasty, while others do not believe it provides a critical function. The purposes of this study were to (1) evaluate the effect of resecting the ...
Honda Miwako M AIDS Clinical Center, National Center for Global Health and Medicine, Japan. - - 2011
The side-effects of anti-retroviral drugs are different between Japanese and Caucasian patients. Severe central nerve system (CNS) side-effects to efavirenz and low rate of hypersensitivity against abacavir characterize the Japanese. The objective of this study was to select a once daily regimen for further non-inferior study comparing the virological efficacy ...
Kuipers Ernst J - - 2011
Efficacy of a continuous high-dose intravenous infusion of esomeprazole, followed by an oral regimen after successful endoscopic therapy for peptic ulcer bleeding (PUB) was established in the PUB study (ClinicalTrials. gov identifier: NCT00251979). Mortality rates and detailed safety and tolerability results from this study are reported here. This was a ...
He Lei - - 2010
PURPOSE: To compare the efficacy and safety of Shockwave lithotripsy (SWL) for upper urinary tract stones of various locations in children. METHODS: Between 1997 and 2008, a total of 311 children (average age: 7.9 ± 4.4 years, ranged from 6 months to 16 years) with upper urinary tract stones were treated by SWL using Dornier ...
Landsman Adam Scott - - 2011
A biologically active human skin allograft, currently distributed under the brand name TheraSkin(®), was examined for safety and efficacy in the treatment of venous leg ulcers (VLUs) and diabetic foot ulcers (DFUs). The objective was to determine if TheraSkin could serve as a safe and effective alternative to bioengineered skin ...
Jayakumar Avula - - 2011
the objective of the study was to evaluate the safety and efficacy of a formulation containing recombinant human platelet-derived growth factor (rhPDGF-BB) and β-tricalcium phosphate (β-TCP) in patients with periodontal defects and to compare it with those of β-TCP alone. in this double-blind, prospective, parallel, active-controlled, randomized, multi-centre clinical trial, ...
Appendino Giovanni - - 2010
In a previous three-month study of Meriva, a proprietary curcumin-phosphatidylcholine phytosome complex, decreased joint pain and improvement in joint function were observed in 50 osteoarthritis (OA) patients. Since OA is a chronic condition requiring prolonged treatment, the long-term efficacy and safety of Meriva were investigated in a longer (eight months) ...
Solako─člu Can - - 2010
This study aims to point out the long-term results of fibrin sealant in the treatment of acute ruptures of the Achilles tendon. Between January 1998 and December 2007, 42 patients (42 males; mean age 37.8 years; range 27 to 56 years) admitted to our clinic for acute ruptures of the ...
White Kacey L - - 2010
To biomechanically compare construct elongation under loading conditions and to compare load to failure for the locking premanufactured loop stitch versus the Krackow stitch. Twenty porcine Achilles tendons were randomly assigned to receive the locking Krackow stitch with No. 2 FiberWire (Arthrex, Naples, FL) or the locking premanufactured loop stitch ...
Crim Julia - - 2010
The purpose of this article is to assess the changes occurring over time in the MRI appearance of repaired rotator cuff tendons and to correlate MRI appearance with clinical outcomes. MRI examinations were performed on 40 patients with full-thickness rotator cuff tears preoperatively and at 6 weeks, 3 months, and ...
Miranda R I - - 2010
Management of atrial fibrillation (AF) has changed greatly in the past 10 years. The advent of a greater understanding of the pathophysiology of AF has resulted in major therapeutic breakthroughs, both in invasive and non-invasive strategies. New antiarrhythmic agents with fewer side effects, new anticoagulants and technical advances in ablation ...
Saxena Amol - - 2011
Return to activity (RTA) following Achilles tendon surgery assessment criteria has not been generally adopted. A well-defined postsurgical rehabilitation regimen with 3 distinct criteria, yet easy to measure, can be used to assess the ability of patients undergoing Achilles tendon surgery to return to activity. We studied whether if patients ...
Konstan Michael W MW Rainbow Babies and Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, OH, USA. - - 2011
A light-porous-particle, dry-powder formulation of tobramycin was developed, using PulmoSphere® technology, to improve airway delivery efficiency, substantially reduce delivery time, and improve patient convenience and satisfaction. We evaluated the safety, efficacy and convenience of tobramycin inhalation powder (TIP™) versus tobramycin inhalation solution (TIS, TOBI®) for treating Pseudomonas aeruginosa infection in ...
Kotkansalo T - - 2011
The purpose of this study was to evaluate the long-term functional results of microvascular toe-to-thumb reconstruction after trauma. Forty-one patients meeting the inclusion criteria were available for a clinical follow-up study. The function of the hand was assessed with questionnaires as well as with modified Tamai and Sollerman hand function ...
Hsu Andrew R - - 2011
There are significant differences in incidence of cosmetic deformity and load to tendon failure between biceps tenotomy versus tenodesis for the treatment of long head of the biceps brachii (LHB) tendon lesions which are supported by the evidence-based strengths and weaknesses of each procedure in the literature. PubMed, Embase, and ...
Schepull Thorsten T Department of Clinical and Experimental Medicine, IKE, Linköping University, - - 2011
Animal studies have shown that local application of platelet-rich plasma (PRP) stimulates tendon repair. Preliminary results from a retrospective case series have shown faster return to sports. Autologous PRP stimulates healing of acute Achilles tendon ruptures. Randomized controlled trial; Level of evidence, 2. Thirty patients were recruited consecutively. During surgery, ...
Al-Qattan M M - - 2011
Over an eight-year period, the author has treated five males (mean age of 31 years) with clean-cut zone 2 lacerations of both flexor tendons of all fingers using the same surgical technique (profundus only repair using three 'figure of eight' core sutures and proximal venting of the pulley system) and ...
Patterson J Megan M - - 2010
The transfer of flexor carpi ulnaris (FCU) to extensor carpi radialis brevis (ECRB) (the Green transfer) in children with cerebral palsy (CP) is a surgical option frequently used to address the typical wrist flexion deformity that is often present in these patients. We hypothesize that late deformities may occur when ...
Corrado Michael L - - 2010
Treatment of complicated skin and skin structure infections (cSSSIs) requires therapy that is effective against a range of Gram-positive and Gram-negative bacteria, including resistant pathogens such as methicillin-resistant Staphylococcus aureus. Equally important is the need to provide therapy that is safe and well tolerated. Ceftaroline fosamil is a new-generation, parenteral ...
Housner Jeffrey A - - 2010
To report the retrospective results of ultrasound-guided needle fenestration for the treatment of recalcitrant patellar tendinopathy. Retrospective follow-up study. University outpatient sports medicine clinic. Forty-seven patellar tendons in 32 patients (26 men and 6 women; mean age, 26 years) with recalcitrant patellar tendinopathy. Diagnosis made via history, physical examination, and ...
Willits Kevin - - 2010
To date, studies directly comparing the rerupture rate in patients with an Achilles tendon rupture who are treated with surgical repair with the rate in patients treated nonoperatively have been inconclusive but the pooled relative risk of rerupture favored surgical repair. In all but one study, the limb was immobilized ...
Dabas V - - 2011
We assessed the effect of an early transfer of pronator teres to extensor carpi radialis brevis on hand function in patients with high radial nerve paralysis. Power grip and precision grip were measured preoperatively and postoperatively using a dynamometer. Fifteen patients were operated on, of which ten could be assessed ...
Thomopoulos Stavros - - 2010
Studies have demonstrated that flexor tendon repair strength fails to increase in the first three weeks following suturing of the tendon, a finding that correlates closely with the timing of many clinical failures. The application of growth factors holds promise for improving the tendon-repair response and obviating failure in the ...
Cacchio Angelo - - 2011
Chronic proximal hamstring tendinopathy is an overuse syndrome that is usually managed by nonoperative methods. Shockwave therapy has proved to be effective in many tendinopathies. Shockwave therapy may be more effective than other nonoperative treatments for chronic proximal hamstring tendinopathy. Randomized controlled clinical study; Level of evidence, 1. Forty professional ...
Christman Catherine - - 2011
Background Current neonatal guidelines endorse both the two-thumb and the two-finger techniques for performing chest compressions. It remains unclear whether one method is superior to the other in achieving consistent depth. Objective To compare the compression depth, variability, rate and finger placement of the two-thumb and two-finger techniques using a ...
Malizos Konstantinos N - - 2010
Thirty-four patients with spastic upper extremity secondary to cerebral palsy underwent operative treatment with bony and soft tissue procedures including osteotomies, capsulotomies tendon transfers, lengthening and releases. The follow-up ranged from 24 months to 9 years with a mean of 52 months. For the evaluation of the surgical outcome patients ...
- - 2010
In the article Adjustable superior oblique tendon spacer with application of nonabsorbable suture for treatment of isolated inferior oblique paresis by Masoud A. Fard et al, published in Eur J Ophthalmol 2010; 20: 659-663, the paragraph RESULTS of the Abstract (page 659) reported a wrong value: The mean duration of ...
Tauber Mark - - 2010
BACKGROUND: Latissimus dorsi tendon transfer is a well-established method for the treatment of massive irreparable posterosuperior defects of the rotator cuff. Subsequent rupture of the transferred tendon may contribute to the rate of failure of the index procedure. We hypothesized that modification of our technique of tendon harvesting would lead ...
Carda S - - 2010
This study assessed if transfer of the extensor hallucis longus is a valid alternative treatment to split transfer of the tibialis anterior tendon in adult hemiplegic patients without overactivity of the tibialis anterior. One group of 15 patients had overactivity of tibialis anterior in the swing phase, and underwent the ...
Hall Barbara - - 2010
This pilot study compared the effectiveness of 3 postoperative rehabilitation protocols for patients with Zones V and VI extensor tendon lacerations. Twenty-seven patients were recruited from 3 sites and randomly assigned to 1 of 3 established treatment protocols: immobilization, early passive motion (EPM), and early active motion (EAM). Outcome measures ...
Arsiwala Shehnaz Z - - 2010
Correction of nasolabial creases through minimally invasive procedures is increasingly being sought by patients. Injecting non-animal stabilized hyaluronic acid filler is a highly effective method to achieve an optimal and persistent cosmetic result To evaluate the efficacy, persistence and safety of Restylane and Perlane (Q-Med, Sweden) for correction of nasolabial ...
Al-Qattan Mohammad M - - 2011
There is a paucity of the literature on the outcome of zone III flexor tendon injuries. In this paper, we report on the results of zone III flexor tendon repair in 35 consecutive adult patients with clean cut lacerations of both flexor tendons in 42 fingers. There were 25 men ...
Sierakowski A - - 2011
This paper presents outcomes after 13, 4, and 3½ years in three digital amputees treated with osseointegrated prostheses. One had prosthetic replacement of the index and middle fingers at the PIP level. The second had four fingers replaced at the PIP level, but only three prostheses were retained. The third ...
Nilsson-Helander Katarina - - 2010
There is no consensus regarding the optimal treatment for patients with acute Achilles tendon rupture. Few randomized controlled studies have compared outcomes after surgical or nonsurgical treatment with both groups receiving early mobilization. This study was undertaken to compare outcomes of patients with acute Achilles tendon rupture treated with or ...
Chiodo Christopher P - - 2010
This clinical practice guideline is based on a series of systematic reviews of published studies in the available literature on the diagnosis and treatment of acute Achilles tendon rupture. None of the 16 recommendations made by the work group was graded as strong; most are graded inconclusive; four are graded ...
Wood Viviane T - - 2010
The treatment of calcaneal tendon injuries requires long-term rehabilitation. Ultrasound (US) and low-level laser therapy (LLLT) are the most used and studied physical agents in the treatment of tendon injuries; however, only a few studies examined the effects of the combination of US and LLLT. Therefore, the purpose of this ...
Muramatsu Keiichi - - 2010
Complications after the harvesting of vascularized fibula grafts are rare. Here we present our results on patients who developed claw deformity of the great and lesser toes. We discuss the etiology of claw toe deformity and the surgical correction of this condition. Seven patients developed claw toe deformity in the ...
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