Search Results
Results 351 - 400 of 1394
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Lee Inn-Chi - - 2007
BACKGROUND: The present study aimed to elucidate the clinical characteristics and outcomes of three types of occipital epileptic syndromes: early-onset and late-onset childhood epilepsy with occipital paroxysm (ECEOP and LCEOP) and symptomatic occipital epilepsy (SOLE). METHODS: We retrospectively reviewed the medical records of 54 children (18 ECEOP, 10 LCEOP, and ...
Lin Tina W - - 2007
Conventional visual analysis of brain (18)F-FDG PET scans is useful for predicting postsurgical improvement for temporal lobe epilepsy (TLE) patients, but prognostic value for identifying patients who will achieve seizure-free status is considerably lower. We aimed to develop an approach with which to quantitatively assess prognostically pertinent aspects of metabolic ...
Sevmis S - - 2007
The aim of this study was to analyze liver transplant patients who had tacrolimus (TAC)-related seizures at our institution during the early postoperative period. Between September 2001 and June 2006, liver transplantation (LT) was performed in 132 patients. All received a TAC-based immunosuppressive protocol after LT. Twelve (9%; 1 woman, ...
Zhang Haishi - - 2007
OBJECTIVE: To discover serum biomarkers in astrocytoma patients for early detection of glioma and evaluation of prognosis. METHODS: A total of 140 serum samples were analyzed using the weak cation-exchange (WCX) chips. Among those, 73 were sera from astrocytoma patients, 56 from normal controls, and 11 from other brain tumors. ...
Celis M A - - 2007
OBJECTS: To show the clinical results of a corpus callosotomy (CC) treatment using conformal stereotactic radiosurgery (SRS) on a patient with medically intractable multifocal epilepsy. MATERIALS AND METHODS: A 17-year-old male patient underwent corpus callosotomy conformal SRS using a dedicated linear accelerator (linac) with dynamic arcs technique. The prescribed dose ...
Pondal-Sordo Margarita - - 2007
BACKGROUND AND PURPOSE: In patients with discordant results, non-localizing EEG, or bitemporal seizure onset, intracranial monitoring is done to confirm the seizure onset. Our aim was to assess the yield of intracranial recordings in patients with different clinical scenarios. METHODS: The records of all patients who underwent prolonged intracranial EEG ...
von Stuelpnagel Celina - - 2007
OBJECTIVE: To assess the efficacy and tolerability of Levetiracetam (LEV) in children and adolescents with refractory epilepsy with a special interest in the long-term retention rate. METHOD: One hundred and twenty-nine patients (83 male, 46 female; mean age 10.6 years/range: 6 months-39 years 9 months) were included in a prospective, ...
Paul Friedemann - - 2007
Some patients undergoing epilepsy surgery suffer from early postoperative seizures which may have a negative impact on later outcome. Factors contributing to these seizures have not to date been examined systematically. We hypothesized that reduction of postoperative serum levels of antiepileptic drugs (AED) may be one risk factor for early ...
Schmidt D - - 2007
Assessing if an early therapeutic response to an antiepileptic drug (AED) is of prognostic value for long-term outcome is of considerable clinical interest. To that end, we evaluated the likelihood that a patient who becomes seizure-free after 6 months of treatment with a single AED would lose that response at ...
Bahi-Buisson N - - 2007
Rasmussen encephalitis (RE) is a severe and progressive focal epilepsy of unknown origin that leads to deterioration of motor and cognitive function. In a previous study, we described positive effect of high doses of steroids during the first year after the onset of RE. The objective of this study was ...
Kertesz Andrew - - 2007
The course of frontotemporal dementia (FTD) is examined in a prospective, incipient clinical cohort. Three hundred nineteen patients were followed yearly for an average of 3.6 years. The relative frequencies at presentation were Behavioral variety (FTD-bv) 37.6%, Primary Progressive Aphasia (PPA) 31.6%, possible PPA 10.6%, Corticobasal Syndrome (CBDS) and Progressive ...
Lucas Richard E - - 2007
Hedonic adaptation refers to the process by which individuals return to baseline levels of happiness following a change in life circumstances. Two nationally representative panel studies (Study 1: N = 39,987; Study 2: N = 27,406) were used to investigate the extent of adaptation that occurs following the onset of ...
Tanriverdi Taner - - 2007
BACKGROUND: The aim of this study was to compare neuropsychological outcome at 1-year follow-up in patients with medically refractory unilateral mesial temporal lobe epilepsy (MTLE) due to hippocampal sclerosis (HS) treated by a cortico-amygdalohippocampectomy (CAH) or a selective-amygdalohippocampectomy (SAH). METHODS: Data for a series of 72 adult patients who underwent ...
Balasubramaniam P - - 2007
Lichen sclerosus is a common condition affecting the vulva and long-term follow-up is recommended. We audited a group of patients discharged from the vulval clinic and found that 38% had not seen their GP 12 months after discharge. Of those that were seen, 17% were not examined. Further education is ...
De Herdt Veerle - - 2007
INTRODUCTION: Vagus nerve stimulation (VNS) is a symptomatic add-on treatment for patients with medically refractory epilepsy. It consists of continuous electrical stimulation of the left vagus nerve by means of a helical electrode and an implantable, programmable pulse generator. Currently, over 50,000 patients are treated with VNS worldwide. AIM: This ...
Kadir A - - 2008
The effect of galantamine treatment on cortical acetylcholinesterase (AChE) activity and nicotinic receptor binding was investigated by positron emission tomography (PET) in 18 patients with mild Alzheimer's disease (AD) in relation to galantamine concentration and the patients' cognitive performances. The first 3 months of the study was of a randomized ...
Marson Anthony G AG Division of Neurological Science, University of Liverpool, UK. - - 2007
Valproate is widely accepted as a drug of first choice for patients with generalised onset seizures, and its broad spectrum of efficacy means it is recommended for patients with seizures that are difficult to classify. Lamotrigine and topiramate are also thought to possess broad spectrum activity. The SANAD study aimed ...
Heo Kyoung - - 2007
This prospective, open-label study evaluated the efficacy and safety of adjunctive levetiracetam (LEV) in Korean adults with uncontrolled partial epilepsy. Study patients had to have an average of at least 1 and not more than 14 partial seizures per month (averaged over a 3-month historical baseline) despite the use of ...
Radhakrishnan Ashalatha - - 2007
PURPOSE: To investigate the electro-clinical significance of premature accumulation of corpora amylacea (CoA) in the resected hippocampus of patients with medically refractory mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS). METHODS: We compared the clinical and EEG characteristics, and post-operative seizure outcome of 373 (mean age 29.4 years, range 7-55 ...
Holsti Maija - - 2007
BACKGROUND: The local emergency medical services (EMS) council implemented a new pediatric treatment protocol using a Mucosal Atomization Device (MAD) to deliver intranasal (IN) midazolam for seizure activity. METHODS: We sought to compare outcomes in seizing pediatric patients treated with IN midazolam using a MAD (IN-MAD midazolam) to those treated ...
Seo Jong-Geun - - 2007
This study compared the cognitive effects of 1 year of treatment with lamotrigine (LTG) and oxcarbazepine (OXC) in epilepsy patients. This retrospective study investigated 60 epilepsy patients undergoing neuropsychological tests who were either newly diagnosed or untreated in the preceding 6 months. The cognitive function in 30 patients receiving LTG ...
Korinthenberg Rudolf - - 2007
The aim of this study is to investigate the efficacy and tolerability of topiramate in a large number of children with West syndrome. The authors performed a retrospective, questionnaire-based data collection in specialized epilepsy units in Germany. Patients with West syndrome and hypsarrhythmia could be included if topiramate treatment had ...
Elger Christian - - 2007
OBJECTIVE: To explore the efficacy and safety of eslicarbazepine acetate (BIA 2-093), a new antiepileptic drug, as adjunctive therapy in adult patients with partial epilepsy. METHODS: A multicenter, double-blind, randomized, placebo-controlled study was conducted in 143 refractory patients aged 18-65 years with >or=4 partial-onset seizures/month. The study consisted of a ...
Sinha S - - 2007
Epilepsia Partialis Continua (EPC), a subtype of status epilepticus has varied etiology and the outcome depends on the cause. The aim of this study was to analyze the demographic, semiology, etiology, radiological findings, therapeutic response and outcome of EPC. This is a retrospective analysis of 76 patients (M:F: 46:30; mean ...
Turner Martin R MR Department of Neurology, The Radcliffe Infirmary, Oxford, UK. - - 2007
Four PLS patients underwent cerebral [(11)C]-flumazenil PET. They were compared firstly with a group of controls, then later directly with a group of sporadic ALS patients and a familial ALS group homozygous for the 'D90A' SOD1 gene mutation. There was a similar pattern of decreased binding in PLS patients when ...
Kral T - - 2007
BACKGROUND: Studies of long term outcome after epilepsy surgery for cortical malformations are rare. In this study, we report our experience with surgical treatment and year to year long term outcome for a subgroup of patients with focal cortical dysplasia (FCD). METHODS: We retrospectively analysed the records of 49 patients ...
Hsieh Wen Bin - - 2007
BACKGROUND AND PURPOSE: Herpes simplex encephalitis (HSE) can cause high mortality and morbidity in children. Since local data of HSE in children are rare, we performed a retrospective study to evaluate the prognostic factors and outcome of HSE in Taiwan. METHODS: Children were enrolled into this study if they were ...
Andrade-Filho Antônio de Souza Ade - - 2007
Neurocysticercosis (NCC) is a common parasitic disease in our region, presenting diversity of neurological symptoms and signs. The present study has as primary objective an evaluation of the NCC's clinical and epidemiological profile within Bahia State, by means of a prospective study of 220 patients diagnosed from March 1988 to ...
Yamamoto Hitoshi - - 2007
West syndrome (WS) is a severe age-dependent intractable epilepsy in infants that frequently results in mental retardation. ACTH or glucocorticoids are among several effective treatments in WS, but the relative advantages and disadvantages of these two therapies are still unknown. In a previous study, liposteroid (LS; dexamethasone palmitate) was used ...
Lim Siew-Na - - 2007
PURPOSE: The anterior nucleus of the thalamus (ANT) modulates temporal lobe and hypothalamic activities, and relays information to the cingulate gyrus and entorhinal cortex. Deep brain stimulation (DBS) of the ANT has been reported to decrease seizure activity in a limited number of human subjects. However, long-term effect of chronic ...
Asztely Fredrik - - 2007
OBJECTIVE: To compare long term (10 years) seizure outcome, psychosocial outcome and use of antiepileptic drugs (AED) with the 2 year follow-up in adults after resective epilepsy surgery. METHODS: All adults (n = 70) who underwent resective epilepsy surgery from 1987 to 1995 in the Göteborg Epilepsy Surgery Series were ...
Blümcke Ingmar - - 2007
We propose a histopathological classification system for hippocampal cell loss in patients suffering from mesial temporal lobe epilepsies (MTLE). One hundred and seventy-eight surgically resected specimens were microscopically examined with respect to neuronal cell loss in hippocampal subfields CA1-CA4 and dentate gyrus. Five distinct patterns were recognized within a consecutive ...
Sureka R
<b>Objectives: </b> To study the knowledge, attitudes, and beliefs about the causes and the treatment of epilepsy in rural North West India in the year 2000 and, again after 4 years, to study the effects of health education and regular treatment on the same parameters. <b> Materials and Methods: </b> ...
Sharma Shri Ram
This study was planned to evaluate the role of steroid alone and with albendazole in patients of single-small enhancing computerized tomography (CT) lesions in Indian patients presenting with new-onset seizures. In this study, 95 patients with new onset seizures and a single enhancing CT lesion were randomly divided in two ...
Varshney J P - - 2007
Epilepsy is an important neurological disorder in dogs. Belladonna 200C was evaluated in 10 dogs with idiopathic epilepsy. During the seizure phase, 3-4 drops of Belladonna 200C were administered orally at 15 min intervals until considerable reduction in seizure activity, then four times daily. Four dogs with head shaking syndrome ...
Okumura Akihisa - - 2007
The authors report the case of a surviving twin patient with severe brain malformation due to intrauterine fetal demise of the other twin. The patient was a boy with 37 weeks of gestational age. Intrauterine death of the co-twin was discovered at 18 weeks of gestation. No major anomalies were ...
Chumnanvej Sorayouth - - 2007
OBJECTIVE: Phenytoin (PHT) is widely administered after subarachnoid hemorrhage, often for several weeks or months. In addition to known side effects, PHT use has been correlated with cognitive disability and poor outcome. To reduce the rate of PHT complications, we converted from a multi-week prophylactic regimen to a 3-day course ...
Fountas Kostas N - - 2007
BACKGROUND: Implantation of subdural strip and grid electrodes is a common methodology in the invasive evaluation of patients with medically refractory epilepsy. Although their implantation is safe, the occurrence of implantation-associated complications can occasionally be troublesome. METHODS: In our current retrospective study, 185 patients undergoing subdural grid/strip implantation for invasive ...
Werner Tamara - - 2007
PURPOSE: To determine the influence of valproate (VPA) treatment on acylcarnitines in children with epilepsy. METHODS: Determination of acylcarnitines (including free carnitine and acylcarnitines from C2 to C18) in dried blood spot specimens using tandem-mass spectrometry. Longitudinal study of changes in acylcarnitines in children under VPA treatment without pretreatment (group ...
Kossoff Eric H - - 2007
OBJECTIVE: The concept of "rational polypharmacy" has been associated with anticonvulsant management for decades, but the term has not been applied to nonpharmacologic therapies. METHODS: We conducted a multicenter, retrospective study of children who received concurrent diet (ketogenic or modified Atkins) and vagus nerve stimulation (VNS) treatment for medically intractable ...
Leone Maurizio A - - 2006
We followed 419 patients with a first, unprovoked, primarily or secondarily generalized tonic-clonic seizure, randomized to immediate antiepileptic treatment or to treatment only in the event of seizure recurrence. The probability of achieving a 2-year remission was 72 vs 57% at 3 months, 84 to 79% at 3 years, and ...
Yeh J S - - 2006
Phenytoin is often used to prevent postcraniotomy seizures, but is not always effective. We investigate changes in plasma phenytoin level ([phenytoin]) following craniotomy. The [phenytoin] in 28 patients who were receiving phenytoin (oral/ intravenous) and undergoing a craniotomy were prospectively measured 24 h preoperatively, immediately pre- and postcraniotomy, 24 and ...
Dupont Sophie - - 2006
PURPOSE: To assess the seizure-freedom rates and self-perceived psychosocial changes associated with the long-term outcome of epilepsy surgery in patients with refractory medial temporal lobe epilepsy associated with hippocampal sclerosis. METHODS: A standard questionnaire was given to 183 patients who underwent surgery between 1988 and 2004, and 110 were completed. ...
Téllez-Zenteno José F - - 2007
Assessment of long-term outcomes is essential in brain surgery for epilepsy. Little information exists on long-term non-seizure outcomes after epilepsy surgery. We perform a systematic review and meta-analysis of the evidence on this topic. Our aim was to provide evidence-based estimates of antiepileptic drug, psychosocial, neuropsychological and mortality long-term outcomes ...
Taplin Craig E - - 2006
Cerebral salt wasting is an increasingly recognized condition in pediatrics and is characterized by inappropriate natriuresis and volume contraction in the presence of cerebral pathology. Diagnosis can be difficult and therapy challenging. A few single case reports of the successful use of fludrocortisone exist. We report 4 patients with cerebral ...
Klein Andrea - - 2007
Opsoclonus-myoclonus syndrome (OMS) in children is a rare neurological condition with opsoclonus, myoclonus, ataxia and irritability in the first 2 years of life. It can be idiopathic, parainfectious, or paraneoplastic with tumours of the neural crest. Few studies of long-term follow-up after OMS have been published. We investigated the motor, ...
Aleman Monica - - 2006
BACKGROUND: Epilepsy is relatively uncommon in horses compared with other species and limited information is available. HYPOTHESIS: The objectives of the study were to describe the age of onset, clinical signs, clinicopathologic data, electroeticephalographic findings, treatment, and outcome, including long-term prognosis in Arabian foals with idiopathic epilepsy. ANIMALS: Twenty-two foals ...
Bien Christian G - - 2006
PURPOSE: It is difficult to validly assess the long-term effect of epilepsy surgery. Here, this is attempted by comparing the outcome of surgically treated pharmacoresistant epilepsy patients to three different nonoperated comparison groups regarding seizure control, antiepilepsy drug (AED) usage, and health related quality of life (QOL). METHODS: One hundred ...
Ersoy-Evans Sibel - - 2007
BACKGROUND: Pityriasis lichenoides (PL) occurs in all age groups, although predominantly in younger individuals. OBJECTIVE: We sought to study the clinical features of PL in children followed up at our institution. METHODS: The records of 124 children who were given the diagnosis of PL at our institution between 1993 and ...
Erickson Craig A - - 2007
RATIONALE: There are no drugs that have been shown to effectively treat the core social impairment of autism. OBJECTIVES: The purpose of this study was to examine the effectiveness and tolerability of memantine for social impairment in children and adolescents with pervasive developmental disorders (PDDs). MATERIALS AND METHODS: Medical records ...
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