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Results 101 - 150 of 2027
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Dewilde Sarah - - 2011
OBJECTIVE: To determine the cost-effectiveness of adding eptifibatide to the standard treatment for selected high-risk patients undergoing coronary stenting in Germany. Furthermore, to investigate the impact of several extrapolation methods on the results. METHODS: A Markov model was developed to reflect the clinical events in this specific patient population, including ...
Gelsomino Sandro - - 2011
OBJECTIVE: Cost-effectiveness of heart surgery for elderly patients is still poorly defined. We evaluated outcome, quality of life (QoL), cost, and cost-effectiveness of octogenarians undergoing cardiac surgery. METHODS: One thousand six hundred forty octogenarians undergoing various cardiac surgical procedures were prospectively studied between January 1998 and January 2009 and compared ...
Leroi Anne-Marie - - 2011
BACKGROUND:: Sacral nerve modulation (SNM) is an established treatment for urinary and fecal incontinence in patients for whom conservative management has failed. OBJECTIVE:: This study assessed the outcome and cost analysis of SNM compared to alternative medical and surgical treatments. METHODS:: Clinical outcome and cost-effectiveness analyses were performed in parallel ...
Koo Vincent - - 2011
Study Type - Therapy (cost effectiveness) Level of Evidence 2b What's known on the subject? and What does the study add? Stone management economics is a complex issue. FURS and SWL are recognised treatment option for lower pole kidney stones. There are paucity of data comparing cost implication and effectiveness of ...
de Korte N - - 2011
Aim:  Conservative treatment of mild colonic diverticulitis usually consists of observation, restriction of oral intake, intravenous fluids and antibiotics. The beneficiary effect of antibiotics remains unclear. The aim of this study is to evaluate the need for antibiotics in mild colonic diverticulitis. Method:  A retrospective case-controlled study was performed in ...
Bizarro Pedro - - 2011
Objectives: In the present study, we determined the cumulative costs and outcomes of endovascular treatment of thrombosed autogenous arteriovenous fistulae (AVF) at our medical center. Background: Previous studies examining the salvage procedures of thrombosed AVFs have focused exclusively on clinical outcomes, and, in the absence of costing data, current guidelines ...
Huang Bin-Tao - - 2011
High-dose arabinoside (HiDAC) and daunorubicin (DNR)-based chemotherapy are the primary consolidation treatment options for older adults (50-60 years old) with acute myeloid leukemia in China. We analyzed the event-free survival (EFS) and hospital treatment charges of older adult patients with different cytogenetic risk profiles. In patients with a better/intermediate risk profile, ...
Hullfish Kathie L - - 2011
To compare the relative cost effectiveness of treatment decision alternatives for post-hysterectomy pelvic organ prolapse (POP). A Markov decision analysis model was used to assess and compare the relative cost effectiveness of expectant management, use of a pessary, and surgery for obtaining months of quality-adjusted life over 1 year. Sensitivity ...
Mahoney Elizabeth M - - 2011
Objectives: To evaluate the cost-effectiveness of carotid stenting vs. carotid endarterectomy using data from the SAPPHIRE trial. Background: Carotid stenting with embolic protection has been introduced as an alternative to carotid endarterectomy for prevention of cerebrovascular and cardiovascular events among patients at increased surgical risk. Methods: Between August 2000 and ...
Narayan Pradeep - - 2011
Objective: Endovascular treatment is increasingly used to treat complicated aortic pathology. The aim of the study was to assess if compared with operative repair, thoracic endovascular repair of aorta (TEVAR) was associated with a cost benefit in management of diseases affecting the descending thoracic aorta. We also compared early and ...
Anne-Marie Leroi - - 2011
BACKGROUND:: Sacral nerve modulation (SNM) is an established treatment for urinary and fecal incontinence in patients for whom conservative management has failed. OBJECTIVE:: This study assessed the outcome and cost analysis of SNM compared to alternative medical and surgical treatments. METHODS:: Clinical outcome and cost-effectiveness analyses were performed in parallel ...
Lier D D Institute of Health Economics, Edmonton, Alberta, - - 2011
To conduct an economic evaluation of the use of trans-obturator tape (TOT) compared with tension-free vaginal tape (TVT) in the surgical treatment of stress urinary incontinence (SUI) in women. Cost utility analysis from public-payer perspective, conducted alongside a randomised clinical trial (RCT). Health services provided in Alberta, Canada. A total ...
Bhattacharyya Neil - - 2011
Objective. To quantify the cost burden and utilization of health care for chronic rhinosinusitis (CRS). Study Design. Historical cohort study. Setting. Academic medical centers. Methods. Medical claims data from 2003 to 2008 were analyzed. Patients were defined as having chronic sinus disease if they had a minimum of 2 CRS-related ...
Hallert Eva - - 2011
Objective. To explore possible association between disease activity at 3-month follow-up after RA diagnosis and costs over the following 4 years. Methods. Three-hundred and twenty patients with early (≤1 year) RA were assessed at regular intervals. Clinical and laboratory data were collected and patients reported health-care utilization and number of ...
Colak Mehmet - - 2011
PURPOSE: The metabolic energy cost of walking is altered by pathological changes in gait. It is thought that anterior cruciate ligament (ACL) deficiency alters the energy requirement for level walking through its effect on gait pattern. In this study, it is hypothesised that the metabolic energy cost of walking would ...
Verhaegen Veronique J O - - 2011
The 2 most frequently used endoscopic methods to treat Zenker's diverticulum are staple-assisted and CO(2) laser esophagodiverticulostomy. The study centered around a retrospective evaluation of 107 patients with Zenker's diverticulum who were treated endoscopically by CO(2) laser (n = 72) or staple-assisted diverticulostomy (n = 35). Patients in the staple-assisted ...
Hung Chi-Sheng - - 2011
Drug-eluting stents (DESs) have been shown to reduce in-stent restenosis and target vessel revascularization (TVR) in large clinical trials. We conducted this study to elucidate the differences in the cost and clinical outcome of DESs and bare metal stents (BMSs). We retrospectively analyzed the clinical data and costs of patients ...
Shavakhi Ahmad - - 2011
The aim of this study was to determine the efficacy of two methods of colon preparation for colon cleansing in a randomized controlled trial. In this prospective randomized investigator-blinded trial, consecutive outpatients indicated for elective colonoscopy were randomized into two groups. Patients in Senna group took 24 tablets of 11 ...
Andersson Swen-Olof - - 2011
Abstract Objective. The cost of radical prostatectomy (RP) compared to watchful waiting (WW) has never been estimated in a randomized trial. The goal of this study was to estimate long-term total costs per patient associated with RP and WW arising from inpatient and outpatient hospital care. Material and methods. This ...
Skidmore Grant - - 2011
ABSTRACT: STUDY DESIGN: Economic evaluation from the societal perspective using data from various sources including a multicenter, randomized clinical trial.OBJECTIVE: To evaluate the relative cost-effectiveness of interspinous process decompression using the X-STOP Interspinous Spacer (Medtronic, Inc., Sunnyvale, CA) compared to both conservative care (CC) and laminectomy (LAMI) for moderately impaired ...
Antoñanzas F - - 2011
OBJECTIVES: to evaluate the incremental cost-effectiveness ratio (ICER) of the combination therapy with dutasteride and tamsulosin (DUT+TAM) as initiation treatment versus the most used drug in Spain, tamsulosin (TAM), in the treatment of moderate to severe benign prostatic hyperplasia (BPH) with risk of progression. METHODS: a semi-Markov model was developed ...
Amirnia Mehdi - - 2011
Abstract Background: Psoriasis is a common chronic disease. It is estimated that between US$1.6 billion and US$3.2 billion is spent per year to treat psoriasis. Objective: To compare psoralen plus UV-A (PUVA) therapy with topical steroids in moderate plaque psoriasis. Methods: In this randomized, clinical trial with cost analysis, 88 ...
Gómez C - - 2011
OBJECTIVE: We report clinical and functional outcomes obtained after application of an autologous bioengineered composite skin (ABCS) produced in a single Spanish tissue-engineering unit. MATERIALS/METHODS: Twenty-five burned patients treated with ABCS from 1999 to 2007 in five burn centres were included in the study. Mean age was 29 years (SD ...
You Joyce Hs - - 2011
the merit of applying pharmacogenomics in the induction phase of warfarin therapy for personalized dosing is controversial and highly dependent on its cost-effectiveness. published studies on pharmacoeconomics of warfarin pharmacogenomic application are reviewed. A literature search was done using Medline and Embase covering the period 2000 - 2010. Decision tree ...
Eidson J Leigh JL - - 2011
OBJECTIVE: Endoluminal treatment of symptomatic varicose veins (VV) reduces or eliminates inpatient hospital stays, lowers complication rates, and increases revenue for vein care centers adopting the technique. This study compares the outcomes and economics of two treatments for VV. METHODS: Since May 2007, endovenous radiofrequency ablation (RFA) of symptomatic VV ...
Katsinelos Panagiotis P Department of Endoscopy and Motility Unit, G. Gennimatas General Hospital, and 2nd Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, 55132, Thessaloniki, - - 2011
To compare diverse endoscopic interventions in the management of occluded uncovered self-expanding metal stents (SEMSs) that had been placed for palliative treatment of unresectable malignant biliary obstruction. A retrospective review was undertaken in 4 tertiary endoscopic centers to determine optimal management of different types of occluded SEMSs. The technical success ...
Manz M - - 2011
The care for a patient with ulcerative colitis (UC) remains challenging despite the fact that morbidity and mortality rates have been considerably reduced during the last 30 years. The traditional management with intravenous corticosteroids was modified by the introduction of ciclosporin and infliximab. In this review, we focus on the ...
Lee Bruce Y - - 2011
To develop 3 computer simulation models to determine the potential economic effect of using intravenous (IV) antiviral agents to treat hospitalized patients with influenza-like illness, as well as different testing and treatment strategies. Stochastic decision analytic computer simulation model. During the 2009 influenza A(H1N1) pandemic, the Food and Drug Administration ...
Emirleroglu M - - 2011
The aim of this study was to assess the effects of neostigmine on the postoperative ileus and the healing of colon anastomoses. Anastomotic leaks and postoperative ileus are among the most important complications in colorectal surgery. Nutritional status of the patient is one of the most important factors of the ...
Khaykin Yaariv - - 2011
Atrial fibrillation (AF) is a common and frequently disabling chronic condition associated with significant patient morbidity and affecting an increasing stratum of our ageing society. Direct costs related to atrial fibrillation are comprised from direct cost of medical therapy, catheter ablation, and related hospitalizations and imaging procedures, with indirect costs ...
Beppu Kazuko - - 2011
Background and Aim The incidence of ischemic colitis (IC) in Japan has been increasing due to the westernization of diet and the aging population. The aim of this study was to evaluate the relationship between endoscopic findings and clinical severity in IC. Methods This retrospective analysis included 106 cases diagnosed ...
Ruppert Andras - - 2011
Abstract Objective: Deep vein thrombosis and pulmonary embolism - together referred to as venous thromboembolism (VTE) - result in a major burden on healthcare systems. However, to the authors' knowledge no comprehensive review of the economic burden of VTE has so far been published. Methods: A literature search was carried ...
Speroni Karen Gabel - - 2011
Ventilator-associated pneumonia (VAP) accounts for the majority of nosocomial pneumonias, which may increase intensive care and prolonged hospital stays. Endotracheal tubes allowing continuous subglottic suctioning may reduce VAP; however, they are more expensive than standard endotracheal tubes not allowing continuous suctioning. he objective of this study was to measure the ...
Karatepe Oguzhan - - 2011
Leakage from colonic anastomosis is a major complication causing increased mortality and morbidity. Ischemia is a well-known cause of this event. This study was designed to investigate the effects of adrenomedullin on the healing of ischemic colon anastomosis in a rat model. Standardized left colon resection 3 cm above the ...
Sagar Jayesh - - 2011
Colorectal cancer is one of the most common cancer in the western world. Acute colonic obstruction is one of the common presentations of colon cancer. Emergency surgical decompression is the traditional treatment of choice but is associated with high morbidity and mortality. In recent years colonic stents have been used ...
Jimenez-Garc─▒a Rodrigo - - 2011
Hip arthroplasties is one of the most frequent surgical procedures in Spain and are conducted mainly in elderly subjects. We aim to analyze changes in incidence, co-morbidity profile, length of hospital stay (LOHS), costs and in-hospital mortality (IHM) of patients undergoing primary total hip arthroplasty (THA) over an 8-year study ...
Lee Bruce Y - - 2011
To develop 3 computer simulation models to determine the potential economic effect of using intravenous (IV) antiviral agents to treat hospitalized patients with influenza-like illness, as well as different testing and treatment strategies. Stochastic decision analytic computer simulation model. During the 2009 influenza A(H1N1) pandemic, the Food and Drug Administration ...
Baser Onur - - 2011
Venous thromboembolism (VTE) occurs most often during hospitalization for major surgery or trauma but may also occur up to several months after surgery. Since the potential for VTE exists in a range of clinical settings, an assessment of its impact on overall outcomes and costs to the patient and to ...
Ament J D - - 2011
Despite demonstrated cost effectiveness, not all corneal disorders are amenable to type I Boston keratoprosthesis (KPro) implantation. This includes patients with autoimmune diseases, such as Stevens-Johnson syndrome/toxic epidermal necrolysis. Type II KPro is implanted through the eyelids in severe dry eye and cicatricial diseases, and its cost effectiveness was sought. ...
Yiee Jenny H - - 2011
Copious studies exist regarding the use of stents in pediatric pyeloplasty. Most surgeons use either no stent, an internal (Double-J®) stent or an external transanastomotic pyeloureteral stent. We propose the first known study to compare all 3 methods using a decision tree model that incorporates success rates, complications, patient discomfort ...
King Jason C - - 2011
Studies of minimally invasive surgery (MIS) approaches to TKA have shown decreased postoperative pain, earlier return to function, and shorter lengths of stay in the hospital. However, it is unclear whether these differences translate into decreased costs or charges associated with care. We asked whether a minimally invasive approach to ...
Leong Randall K RK Departments Urology Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Center, Maastricht, the - - 2011
Study Type - Therapy (economic analysis). 1b. To assess and compare the costs and effects value of either starting with sacral neuromodulation (SNM) or botulinum toxin A (BTX) treatment in patients with refractory idiopathic overactive bladder from a societal perspective. An economic model comparing SNM with BTX was developed. A ...
Ghogawala Zoher - - 2010
BACKGROUND:: Cervical spondylotic myelopathy (CSM) is the most common cause of spinal cord dysfunction in the United States (US) and in the world. OBJECTIVE:: To determine the feasibility of a randomized clinical trial (RCT) comparing the clinical effectiveness and costs of ventral versus dorsal decompression with fusion surgery for treating ...
van Breugel Nathalie H - - 2010
This study was performed to assess the cost-effectiveness of concomitant ablation surgery (AS) compared to regular cardiac surgery in atrial fibrillation (AF) patients over a one-year follow-up. Cost analysis was performed from a societal perspective alongside a prospective, randomised, double-blinded, multicentre trial. One hundred and fifty patients with documented AF ...
Craver Christopher W - - 2010
Fluconazole is a standard first-line therapy for candidemia/invasive candidiasis (C/IC), based on its efficacy, safety profile, and comparatively low acquisition cost. However, little is known about the total costs associated with fluconazole treatment for this indication, particularly in cases of clinical failure. The aim of this study was to examine ...
Feng Bo - - 2010
Few studies evaluate the cost-effectiveness issues of laparoscopic anterior resection (LAR) for rectal cancer. This study evaluates direct and indirect costs of LAR and its long-term survival rate in rectal cancer patients. This prospective nonrandomized controlled trial included 2 endpoints (direct and indirect costs, and disease-free survival). From January 2003 ...
Sergi Bruno - - 2010
Auditory testing is not routinely performed within 4 to 6 weeks after stapedotomy because hearing acuity is thought to be transiently depressed. The early postoperative effects of the 1-shot carbon dioxide (CO2) laser have never been reported. The purpose of this study is to present data for auditory thresholds measured ...
Indinnimeo M - - 2010
The cost-effectiveness and budget impact of introducing sacral nerve modulation (SNM) as a treatment for fecal incontinence in Italy were evaluated in a simulation model. A decision-analysis model with a Markov submodel was used to represent clinical pathways for treatment of patients with fecal incontinence in a scenario with SNM ...
Byrd J Kenneth - - 2010
To compare the cost of minimally invasive video-assisted thyroidectomy (MIVAT) with conventional thyroidectomy. A cost-effectiveness study and chart review. Academic university hospital. Pediatric and adult patients referred to the Department of Otolaryngology-Head and Neck Surgery for suspicious thyroid nodules, goiters, or known carcinomas. A tertiary care hospital's billing department was ...
Schneider Ralph - - 2010
Treatment options for secondary hyperparathyroidism were significantly amended with the introduction of cinacalcet and paricalcitol. Limitations of resources in public health systems demand detailed analyses of accruing costs. The aim of this study was to compare the costs of these new treatment modalities to surgery. Patients who underwent initial parathyroidectomy ...
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