Search Results
Results 401 - 450 of 4153
< 4 5 6 7 8 9 10 11 12 13 14 >
Chermetz Maddalena M Division of Oral Medicine and Pathology, Department of Dental Science, University of Trieste, Trieste, - - 2013
Oral mucositis is a debilitating side effect of chemotherapy. Laser therapy has recently demonstrated efficacy in the management of oral mucositis (OM). This prospective study was conducted to evaluate the efficacy of class IV laser therapy in patients affected by OM. Eighteen onco-haematological paediatric patients receiving chemotherapy and/or haematopoietic stem ...
Enomoto Yoshinari Y Division of Cardiovascular Medicine, Ohashi Hospital, Toho University Medical Center, 2-17-6 Ohashi, Meguro-ku, Tokyo, 153-8515, - - 2013
In the era of drug-eluting stents (DES), a long-term dual antiplatelet therapy is required to prevent late stent thrombosis. However, in patients with atrial fibrillation (AF), there is a concern that combining warfarin with dual antiplatelet therapy may increase the risk of bleeding. We analyzed 1274 consecutive patients with coronary ...
Kobayashi Ryoji R Department of Pediatrics, Sapporo Hokuyu - - 2013
Meropenem (MEPM) is widely used for treatment of febrile neutropenia. There have been many reports on MEPM for pediatric febrile neutropenia showing success rates of about 50% to 75%. Although intravenous immunoglobulin (IVIG) is widely used for treatment of infection with antibiotics, there has been no report on the efficacy ...
Puente Angela A Gastrointestinal Bleeding Unit. Department of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Autonomous University, Barcelona, - - 2013
Combined therapy with endoscopic variceal ligation (EVL) and ß-blockers±isosorbide mononitrate (ISMN) is currently recommended to prevent variceal rebleeding. However, the role of this combined therapy has been challenged by some studies. We performed a systematic review to assess the value of combined therapy with EVL and ß-blockers±ISMN as compared with ...
Balogh Emese - - 2013
Our objectives were to assess the frequency and sustainability of American College of Rheumatology (ACR)/European League against Rheumatism (EULAR) and Disease Activity Score (DAS)28(4v)-C-reactive protein (CRP) remission 12 months after the initiation of tumour necrosis factor inhibitor (TNFi) therapy in a rheumatoid arthritis (RA) cohort. Data were collected of 273 ...
Jain Kamini K Division of Child Health, School of Clinical Sciences, University of Nottingham, E Floor, East Block, Queen's Medical Centre, Derby Road, Nottingham, UK, NG9 - - 2013
Early diagnosis and treatment of lower respiratory tract infections, particularly those with Pseudomonas aeruginosa, are the mainstay of management of lung disease in cystic fibrosis. When sputum samples are unavailable, treatment relies mainly on cultures from oropharyngeal specimens; however, there are concerns regarding the sensitivity of these to identify lower ...
Jang Mi-Ok MO Department of Infectious - - 2013
There are no well-matched controlled studies comparing azithromycin with doxycycline for the treatment of complicated scrub typhus. A retrospective propensity-score-matched case-control study was performed for patients who presented with complicated scrub typhus and were treated with doxycycline or azithromycin between 2001 and 2011. Data on comorbidities, clinical manifestations, laboratory studies, ...
Parodi Guido G Department of Cardiology, Careggi Hospital, Florence, - - 2013
Aims: Subacute, late, and very late stent thrombosis (ST) may occur after stent implantation, but they are characterised by different underlying pathophysiological mechanisms. We sought to appraise differences between subacute and late/very late ST at the thrombus site by optical coherence tomography (OCT). The Mechanism Of Stent Thrombosis (MOST) study ...
Samadikhah Jahanbakhsh J Tabriz University of Medical Sciences, Tabriz, - - 2014
Purpose: Atrial fibrillation (AF) is the most frequent arrhythmia that follows coronary artery bypass graft (CABG). Patients developing postoperative AF (POAF) have significantly higher mortality rates. The consistent prophylactic effectiveness of statins and vitamin C are well-accepted; however, no evaluation on combined therapy has been performed. We aimed at assessing ...
Lakkireddy Dhanunjaya D Division of Cardiovascular Diseases, Cardiovascular Research Institute, Mid America Cardiology, University of Kansas Hospital & Medical Center, Kansas City, KS. Electronic address: - - 2013
The purpose of this study was to evaluate the feasibility and safety of uninterrupted rivaroxaban during atrial fibrillation (AF) ablation. Optimal periprocedural anticoagulation strategy is essential for minimizing bleeding and thrombo-embolic complications during and after AF ablation. The safety and efficacy of uninterrupted rivaroxaban as a periprocedural anticoagulant for AF ...
Pellicano Clelia - - 2013
Dopamine agonists (DA) are the first-choice drug for treatment of the early stage of Parkinson's disease (PD) in subjects younger than 70 years. Recently, a number of third generation DA have been marketed, including transdermal patch of rotigotine and extended release oral formulation of ropinirole and pramipexole.We investigated the impact ...
Pejcic Ana A Department of Periodontology and Oral Medicine, University of Nis, Nis, - - 2013
Objective: To evaluate the effect of periodontal treatment on gingival overgrowth in a group of renal transplant patients. Subjects and Methods: Twenty-five renal transplant recipients receiving immunosuppressive therapy with cyclosporine A (CsA) were randomly assigned to 2 groups. Group 1 (n = 15) included patients who had been specifically referred ...
Calzetti Stefano S Neurology Unit, Department of Neurosciences, Azienda Ospedaliero-Universitaria of Parma, Parma, Italy, - - 2013
It is currently controversial if and in which terms Parkinson's disease (PD) and restless legs syndrome (RLS) are linked in co-morbid association. In a cohort of 106 de novo PD patients (67 male and 39 female, aged 42-83 years), 15 of them developed RLS, which was prospectively assessed at 6-month intervals from ...
Duan Yun-Fei - - 2013
Hemostasis in thyroid surgery is of utmost importance for a successful surgery and an uneventful postoperative course. Our aim was to evaluate the effectiveness of the FOCUS Harmonic Scalpel in patients undergoing open total thyroidectomy. In this study, 778 patients were randomized into 2groups based on the surgical technique used: ...
Adravanti Paolo P Orthopaedic Surgery Department, Clinic "Città di Parma", Parma, - - 2013
It has been reported that even one year after total knee arthroplasty (TKA), a relevant percentage of patients does not attain complete recovery and indicate unfavourable long-term pain outcome. We compared the clinical outcome of 33 patients undergoing TKA randomly assigned to the control or the pulsed electromagnetic field group (I-ONE ...
Olanow C Warren CW Department of Neurology and Neuroscience, Mount Sinai School of Medicine, New York, NY, USA. Electronic address: - - 2014
Levodopa is the most effective therapy for Parkinson's disease, but chronic treatment is associated with the development of potentially disabling motor complications. Experimental studies suggest that motor complications are due to non-physiological, intermittent administration of the drug, and can be reduced with continuous delivery. We aimed to assess efficacy and ...
Cox Ruth J RJ Occupational Therapy Department, Princess Alexandra Hospital, - - 2013
The use of support workers such as occupational therapy assistants is emerging as a strategy to enhance the health workforce, but there has been little evaluation of the feasibility of expanding support worker roles and responsibilities. This study aimed to implement an advanced occupational therapy assistant-led groups programme in a ...
Notarnicola Angela A Course of Motor and Sports Sciences, Faculty of Medicine and Surgery, University of Study of Bari, Lungomare Starita 1, 70123, Bari, Italy, - - 2013
The application of laser therapy on soft tissue is used for pain relief, anti-inflammation action and biostimulation. The efficiency of High Energy Laser Therapy has not yet been studied on Achilles tendinopathy. The aim of the study is to evaluate the effectiveness of a flow of Cold air and High ...
Chang Shang-Hung SH 1Section of Cardiology, Chang Gung Memorial Hospital, Taoyuan, - - 2013
Clinical predictors of long-term outcomes in patients with critical limb ischemia (CLI) treated with endovascular therapy (EVT) remain unclear. In this study, clinical predictors of long-term outcomes in EVT-treated patients with CLI were investigated. In this prospective, observational study, we analyzed a total of 253 Taiwanese patients with CLI with ...
Seker Ahmet A 1Department of General Surgery, Faculty of Medicine, Harran University , Sanlıurfa , - - 2013
ABSTRACT Background: Radiation therapy is an essential therapeutic modality in the management of a wide variety of tumors. We aimed to investigate the short-term effects of pelvic irradiation on the healing of colon anastomoses and to determine the potential protective effects of β-glucan in this situation. Material and Methods: Sixty ...
Pasquale Timothy R - - 2013
Background: Methicillin-resistant Staphylococcus aureus (MRSA) is a common nosocomial pneumonia (NP) pathogen in US ICUs. Ceftaroline fosamil is a novel cephalosporin with activity against MRSA. Methods: We retrospectively reviewed patients (pts) who received ceftaroline therapy for MRSA NP. Results: A total of 10 pts received ceftaroline from September 2011 to ...
Brugada Josep J Hospital Clinic, University of Barcelona, Barcelona, Spain. Electronic address: - - 2014
Although cardiac resynchronization therapy (CRT) is effective in most patients with heart failure (HF) and ventricular dyssynchrony, a significant minority of patients (approximately 30%) are non-responders. Optimal atrioventricular and interventricular delays often change over time and reprogramming these intervals might increase CRT effectiveness. The SonR algorithm automatically optimizes atrioventricular and ...
Daniel Elbirt E Clinical Immunology, Allergy and AIDS Center Kaplan Medical Center, Affiliated with Hadassah-Hebrew University Medical School Jerusalem, Rehovot, - - 2013
IntroductionIn Israel, highly active antiretroviral therapy is available (at local pharmacies) without cost. Nevertheless, poor adherence, especially of immigrants from Africa, leads to high rate of treatment failures. Our study looked whether direct monthly highly active antiretroviral therapy supply in our AIDS center has an effect on adherence and outcome.MethodsA ...
Sanders-van Wijk Sandra S 1Maastricht University Medical Center, CARIM, Maastricht, the - - 2013
-Therapy guided by N-terminal-proB-type natriuretic peptide (NT-proBNP) levels may improve outcomes in patients with chronic heart failure (HF), especially in younger patients with reduced left-ventricular ejection fraction (LVEF). It remains unclear whether treatment effects persist after discontinuation of the NT-proBNP guided treatment strategy. -TIME-CHF randomized 499 HF patients aged ≥60years ...
Mortimer Alex M AM Department of Neuroradiology, Frenchay Hospital; Bristol, United Kingdom - - - 2013
This is a literature review on to the use of endovascular therapy in hyperacute ischaemic stroke secondary to large vessel occlusion (LVO). The prognosis for LVO is generally poor and the efficacy of intravenous tissue plasminogen activator (IV TPA) in the treatment of this subtype of stroke is questionable. It ...
Hadji P P Department of Gynecology, Endocrinology and Oncology, Philipps University of Marburg, - - 2013
This prospective study evaluated the relationship between arthralgia and compliance during the first year of adjuvant anastrozole therapy in postmenopausal women with hormone receptor-positive early breast cancer. COMPliance and Arthralgia in Clinical Therapy (COMPACT) was an open-label, multicenter, noninterventional study conducted in Germany. Patients had started adjuvant anastrozole 3-6 months ...
Feres Fausto F Instituto Dante Pazzanese de Cardiologia, São Paulo, São Paulo, - - 2013
The current recommendation is for at least 12 months of dual antiplatelet therapy after implantation of a drug-eluting stent. However, the optimal duration of dual antiplatelet therapy with specific types of drug-eluting stents remains unknown. To assess the clinical noninferiority of 3 months (short-term) vs 12 months (long-term) of dual ...
Yamamoto Takayuki T Inflammatory Bowel Disease Center, Yokkaichi Social Insurance Hospital, 10-8 Hazuyamacho, Yokkaichi, Mie, 510-0016, Japan, - - 2013
This prospective study was to evaluate the significance of fecal calprotectin and lactoferrin for the prediction of ulcerative colitis (UC) relapse. Eighty UC patients in remission for ≥3 months on mesalamine as maintenance therapy were included. At entry, stool samples were collected for the measurement of calprotectin and lactoferrin. All patients ...
Ko D-Y DY Department of Dermatology, Skin Cancer Center, College of Medicine, Dong-A University, Busan, - - 2013
Photodynamic therapy (PDT) with methyl aminolevulinate (MAL) is effective for treating multiple actinic keratoses (AKs). Ablative fractional laser (FL) creates vertical channels that may facilitate MAL delivery and improve PDT response. To evaluate the efficacy of FL-assisted PDT (FL-PDT) in treating facial AKs in Korean patients. A prospective randomized non-blinded ...
Bouguen Guillaume G *Division of Gastroenterology, University of California San Diego, San Diego, California; and †Department of Hepato-Gastroenterology, University Hospital of Rennes, Pontchaillou, Inserm U991 University of Rennes 1, Rennes, - - 2013
Mucosal healing (MH) as a treatment target for ulcerative colitis is of growing interest because it is associated with improved clinical outcomes. However, the feasibility and probability of reaching MH in clinical practice is unknown. We therefore evaluated the feasibility of "treating to target" according to endoscopic findings to reach ...
Russo Ricardo A G RA Department of Rheumatology, UCL Institute of Child Health and Great Ormond Street Hospital NHS Foundation Trust, National Amyloidosis Centre, UCL Medical School, Royal Free Campus and Department of Audiology, Great Ormond Street Hospital NHS Foundation Trust, London, - - 2013
Objective. The aim of this study was to determine the short- and long-term efficacy and safety of 8-weekly canakinumab therapy in children with cryopyrin-associated periodic syndromes (CAPS) in routine clinical practice.Methods. A single-centre observational study was performed. Patients were assessed every 8 weeks at a dedicated clinic. Standardized assessments were ...
Kalita Jayantee J Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, - - 2013
Background: Penicillamine is a standard therapy for Wilson disease (WD) but some patients have paradoxical worsening. Predictors of such deterioration have not been evaluated. This study documents frequency and predictors of deterioration following treatment in WD. Methods: 59 consecutive patients with neurologic WD and 4 asymptomatic siblings were prospectively evaluated. ...
Pandit Anil A Division of Cardiovascular Diseases, Mayo Clinic, Scottsdale, Arizona, USA. Electronic address: - - 2013
To review efficacy of percutaneous closure of patent foramen ovale compared with medical therapy in prevention of recurrent strokes in patients with cryptogenic stroke. Electronic databases; PUBMED, EMBASE, Cochrane registry and web of knowledge were searched for relevant studies. In three randomised clinical trials involving 2303 participants, risk of the ...
Kim Mi Na MN Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea; Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea; Liver Cirrhosis Clinical Research Center, Seoul, - - 2013
We examined the durability of the virological response after discontinuing lamivudine (LVD) in chronic hepatitis B (CHB) patients with LVD-resistant hepatitis B virus (HBV), who responded to LVD plus adefovir (ADV) combination therapy, and the outcome of switching to ADV monotherapy compared to maintaining combination therapy. The study enrolled 72 ...
Merlo Marco M Cardiovascular Department, Ospedali Riuniti and University of Trieste, Trieste, 34149, - - 2013
ACE-inhibitors, β-blockers, implantable cardioverter-defibrillator (ICD) and cardiac resynchronization therapy (CRT) improved prognosis of heart failure. We sought to analyse the long-term prognostic impact of evidence-based integrated therapeutic strategies in patients with idiopathic dilated cardiomyopathy (IDCM). From 1978 to 2007, 853 IDCM patients (45 ± 15 years, 72% males) were enrolled and classified as ...
Ganetsky Valerie S VS Department of Pharmacy Practice, Philadelphia College of Pharmacy, University of the Sciences, Philadelphia, - - 2013
Dual antiplatelet therapy has become a mainstay of long-term management of patients after an acute coronary syndrome (ACS). Mortality for these patients remains high despite current evidence-based treatment strategies. The coagulation cascade plays a role in the pathophysiology of ACS, and trials with warfarin in combination with dual antiplatelet therapy ...
Nuti Federica F From Pediatric Gastroenterology and Liver Unit, Sapienza University of - - 2013
The anti-TNFα antibodies infliximab and adalimumab are effective in inducing and maintaining remission in pediatric Crohn's Disease (CD) patients. The aim of the study is to evaluate the long term efficacy and safety of biological therapy in pediatric CD patients followed at a referral center. This work is a retrospective ...
Maniakas A - - 2013
Chronic rhinosinusitis (CRS) has a high potential for recurrence after endoscopic sinus surgery (ESS), despite a postoperative therapy of topical corticosteroid irrigations. Azithromycin (AZI) is a macrolide antibiotic with anti-inflammatory properties that may be of benefit in such steroid-unresponsive patients. Follow-up study was performed to (1) review the effectiveness of ...
Sasaki Hitoshi H Department of Gastroenterology, Juntendo University School of Medicine, Tokyo, - - 2013
Background/Aims: In Japan, a systematic eradication strategy for Helicobacter pylori has been constructed, and consists of a proton pump inhibitor/amoxicillin and clarithromycin (PPI/AC) therapy as the first-line regimen and proton pump inhibitor/amoxicillin and metronidazole (PPI/AM) therapy as the second-line regimen. The cumulative rate of H. pylori eradication has not been ...
Kikuchi Hiroshi H Division of Medicine, Misasa Medical Center, Okayama University Hospital, Misasa, Tottori, Japan ; Division of Internal Medicine, Takamatsu Hospital KKR, Takamatsu, - - 2014
Controlled clinical trials evaluating the efficacy of repeated Waon therapy for patients with chronic obstructive pulmonary disease (COPD) have yet to be conducted. The purpose of the present study was to evaluate whether repeated Waon therapy exhibits an adjuvant effect on conventional therapy for COPD patients. This prospective trial comprised ...
Ng Jonathan K Y JK Sheffield University Medical School, The University of Sheffield, Sheffield, - - 2014
A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed was: Does repeat thymectomy improve symptoms in patients with refractory myasthenia gravis after thymectomy? A total of 189 papers were found using the reported search, of which seven represented the best evidence to ...
Long Hu - - 2013
Low-level laser therapy is claimed to accelerate bone remodeling. The aim of this meta-analysis was to critically appraise current evidence and to determine the effectiveness of low-level laser therapy in accelerating orthodontic tooth movement. PubMed, Web of Knowledge, Embase, CENTRAL, ProQuest Dissertations &Theses, and SIGLE were electronically searched from Jan ...
Lin Victor Chia-Hsiang VC Department of Urology, E-Da Hospital and Department of Nursing, I-Shou University, Kaohsiung, - - 2013
To investigate the treatment outcome of discontinuing 1 medication from 2-year combination therapy for male benign prostatic hyperplasia/lower urinary tract symptoms. Patients with International Prostate Symptom Score ≥8, total prostatic volume (TPV) >30 mL, and maximum flow rate (Qmax) <15 mL/s were randomly assigned to the 5α-reductase inhibitor (5ARI) discontinue (DC-5ARI) or ...
Yuan Yuhong Y Department of Medicine, Division of Gastroenterology, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada, L8S - - 2013
The optimal duration for Helicobacter pylori (H. pylori) eradication therapy is controversial, with recommendations ranging from 7 to 14 days. Several systematic reviews have attempted to address this issue but have given conflicting results and limited their analysis to proton pump inhibitor (PPI), two antibiotics (PPI triple) therapy. We performed ...
Jain Arsh K AK Division of Nephrology, Department of Medicine, , Western University, London, Canada. Electronic address: - - 2013
Several observational studies of hemodialysis patients show an association between early dialysis therapy initiation and increased mortality. Few studies have examined this association among peritoneal dialysis patients. Retrospective cohort study. A cohort of 8,047 incident peritoneal dialysis patients who started dialysis therapy in 2001-2009 and were treated in Canada. Estimated glomerular ...
Shi Jialiang J Research Institute of General Surgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu Province, - - 2013
Pulmonary changes in veno-venous extracorporeal membrane oxygenation (VV-ECMO) are rarely determined. We compared the contribution of VV-ECMO and cannulation based on the observation of pulmonary inflammatory reaction and parenchymal construction in a porcine model of low tidal volume (VT ) ventilation. We also evaluated the effect of adding continuous renal ...
Han Ji Min JM Asan Medical Center, Internal medicine, Seoul, Korea, Republic of ; - - 2013
Background: It is unclear whether differentiated thyroid cancer (DTC) patients classified as intermediate risk group based on the presence of microscopic extra-thyroidal extension (ETE) should be treated with low- or high-doses of radioiodine (RAI) after surgery. We evaluated success rates and long-term clinical outcomes of patients with DTC of small ...
Schuyler Jones W W Department of Medicine, Duke University Medical Center, Durham, North - - 2013
Although atrial fibrillation (AF) occurs frequently in patients hospitalized with acute coronary syndrome (ACS), strategies for prevention of thromboembolic complications are poorly characterized. We sought to examine exposure to warfarin and P2Y12 inhibitors and clinical outcomes among patients with AF and ACS. Patients age >65 years hospitalized with a primary diagnosis ...
Takayama Katsutoshi - - 2013
Periprocedural ischemic stroke is one problem associated with carotid artery stenting (CAS). This study was designed to assess whether preoperative statin therapy reduces the risk of periprocedural ischemic complications with CAS. In this prospective study at 11 centers, patients with carotid artery stenosis (symptomatic ≥50 %, asymptomatic ≥80 %) and a high ...
Smith Lyn A - - 2013
Hemospray TM (TC-325) is a novel hemostatic agent licensed for use in nonvariceal upper gastrointestinal bleeding (NVUGIB) in Europe. We present the operating characteristics and performance of TC-325 in the largest registry to date of patients presenting with NVUGIB in everyday clinical practice. Prospective anonymized data of device performance and ...
< 4 5 6 7 8 9 10 11 12 13 14 >