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Results 401 - 450 of 4169
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Wilasrusmee Chumpon C Department of Surgery, Ramathibodi Hospital, Mahidol University, Bangkok, - - 2013
Maggot wound therapy (MWT) has been used in various wounds including diabetic foot ulcers, venous leg ulcers, pressure ulcers, and acute surgical wounds. However, the efficacy of MWT therapy has been controversial. We therefore conducted a cohort study and a meta-analysis to assess MWT effects. A retrospective cohort study was ...
Moseley Brian D BD Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. Electronic address: - - 2013
Refractory status epilepticus (RSE) is a neurologic emergency associated with significant morbidity and mortality. Alternative therapies are needed for patients who do not respond to more traditional therapies for RSE. We report on a patient with RSE treated with external trigeminal nerve stimulation (eTNS). On admission, the patient was experiencing ...
Scarpelli Pietro P Department of Vascular and Endovascular Surgery University of - - 2013
Aim: To show our experience in the surgical treatment of superficial vein insufficiency of the lower limbs. Subjects and methods: Since 2002 we have performed 659 procedures of endovascular laser therapy (EVLT) (group A) in the treatment of chronic venous insufficiency of the great saphenous vein using a 980 nm ...
Gibon Emmanuel E Department of Reconstructive and Orthopaedic Surgery, Clinical Orthopaedic Research Centre, Université Paris Descartes, Hôpital Cochin (AP-HP), Paris, - - 2013
We asked whether patients under long-term warfarin and managed with current guidelines regarding bridging therapy have a higher complications rate within ninety days following total knee arthroplasty. We retrospectively identified 38 patients under long-term warfarin. They were match-paired with 76 control patients. Our results showed a significant increased rate of ...
Ribaric G G European Surgical Institute, Ethicon Endo-Surgery (Europe) GmbH, Hamburg, Germany, - - 2013
We performed a meta-analysis of weight loss and remission of type 2 diabetes mellitus (T2DM) evaluated in randomized controlled trials (RCTs) and observational studies of bariatric surgery vs conventional medical therapy. English articles published through June 10, 2013 that compared bariatric surgery with conventional therapy and included T2DM endpoints with ...
Okamoto Shozo S Department of Nuclear Medicine, Hokkaido University Graduate School of Medicine, North 15, West 7, Kita-ku, Sapporo, 060-8638, - - 2013
It is sometimes difficult to assess I-131 lung uptake at the initial I-131 therapy because of strong artifacts from I-131 uptake in the thyroid bed. The aim of this study was to analyze the lung uptake at the second I-131 therapy for lung metastasis in patients who did not have ...
Sakai Nobuyuki N Department of Neurosurgery, Kobe City Medical - - 2013
The present study retrospectively analyzed the database of the Japanese Registry of Neuroendovascular Therapy 1 and 2 (JR-NET1&2) to determine annual trends, including adverse events and clinical outcomes at 30 days after undergoing neuroendovascular therapy. JR-NET1&2 are surveys that targeted all patients in Japan who underwent neuroendovascular therapy delivered by ...
Ashraf Alireza A Department of Physical Medicine and Rehabilitation, Shiraz University of Medical Sciences, Shiraz, Iran; Burn Research Center, Shiraz University of Medical Sciences, Shiraz, - - 2013
There is lack of well-designed trials evaluating structural benefits of non-pharmacologic therapies in knee osteoarthritis (OA). In this parallel-group randomized controlled trial, we aim to compare the possible advantages of lateral wedge insole and acupuncture in patients with medial knee OA. Patients with grade two or three of medial knee ...
Rodnitzky Robert L RL From the Department of Neurology (R.L.R., N.S.N.), and Aging, Mind, and Brain Initiative (N.S.N.), University of Iowa College of Medicine, Iowa - - 2013
Levodopa-induced dyskinesia (LID) is one of the most common, frequently dose-limiting, complications of pharmacologic therapy for Parkinson disease (PD). These typically choreiform movements, usually occurring at the time of peak levodopa effect, occur in 40% to 50% of patients after 5 years of therapy, but have a reported incidence as ...
Asher Scott A SA Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, School of Medicine at the University of Alabama at Birmingham, - - 2013
IMPORTANCE Pharyngocutaneous fistula formation after pharyngeal reconstruction is one of the most common and challenging problems to manage. Despite many advances in management, the published success rates indicate a role for any adjuvant therapy that could potentially decrease this complication. OBJECTIVE To describe the use of intraluminal negative pressure dressings ...
Lee Kangwoo N KN Department of Plastic and Reconstructive Surgery, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, South - - 2013
The purpose of this study was to develop and test a novel mode of negative pressure wound therapy (NPWT) that minimises pain while preserving the efficacy in wound healing. A porcine model was used in this study. Wounds were generated in animals and treated with either simple dressing or various ...
Czerwińska-Jelonkiewicz Katarzyna K Department of Acquired Valvular Disease, Institute of Cardiology, Warsaw, - - 2013
Dual antiplatelet therapy (DAPT) - aspirin and clopidogrel - is recommended after transcatheter aortic valve implantation (TAVI) without an evidence base. The main aim of the study was to estimate the impact of antithrombotic therapy on early and late bleeding. Moreover, we assessed the impact of patients' characteristics on early ...
Cesur Mustafa M Department of Endocrinology and Metabolic Diseases, Ankara Guven Hospital, Ankara, - - 2013
Levothyroxine (LT4) therapy has been used for the treatment of euthyroid nodular goiter, but there are controversial results about its usefulness. We aimed to evaluate the possible role of benign nodules' cytological characteristics in response to LT4 therapy. In total, 93 patients with 128 nodules were included in the study; ...
Takama Noriaki N Department of Cardiovascular Medicine, Gunma University School of Medicine, Maebashi, Japan. Electronic address: - - 2013
It is unclear whether adaptive servo-ventilation (ASV) is safe and effective in patients with severe systolic heart failure (HF). Our aim in this study was to estimate the safety and efficacy of ASV therapy for patients with severe systolic HF. Seventy-six HF patients (age: 69±12 years; 53 men), categorized as ...
Sherman Michael M Department of Internal Medicine, San Antonio Uniformed Services Health Education Consortium (SAUSHEC), San Antonio, - - 2013
The aim of this study was to determine whether there were sustained effects of prolonged therapy (≥1 year) with anti-tumor necrosis factor (TNF) agents on the health-related quality of life (HRQoL) in patients with inflammatory bowel disease (IBD). A cross-sectional survey of patients with IBD who were treated with anti-TNF ...
Chermetz Maddalena M Division of Oral Medicine and Pathology, Department of Dental Science, University of Trieste, Trieste, - - 2013
Oral mucositis is a debilitating side effect of chemotherapy. Laser therapy has recently demonstrated efficacy in the management of oral mucositis (OM). This prospective study was conducted to evaluate the efficacy of class IV laser therapy in patients affected by OM. Eighteen onco-haematological paediatric patients receiving chemotherapy and/or haematopoietic stem ...
Enomoto Yoshinari Y Division of Cardiovascular Medicine, Ohashi Hospital, Toho University Medical Center, 2-17-6 Ohashi, Meguro-ku, Tokyo, 153-8515, - - 2013
In the era of drug-eluting stents (DES), a long-term dual antiplatelet therapy is required to prevent late stent thrombosis. However, in patients with atrial fibrillation (AF), there is a concern that combining warfarin with dual antiplatelet therapy may increase the risk of bleeding. We analyzed 1274 consecutive patients with coronary ...
Kobayashi Ryoji R Department of Pediatrics, Sapporo Hokuyu - - 2013
Meropenem (MEPM) is widely used for treatment of febrile neutropenia. There have been many reports on MEPM for pediatric febrile neutropenia showing success rates of about 50% to 75%. Although intravenous immunoglobulin (IVIG) is widely used for treatment of infection with antibiotics, there has been no report on the efficacy ...
Puente Angela A Gastrointestinal Bleeding Unit. Department of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Autonomous University, Barcelona, - - 2013
Combined therapy with endoscopic variceal ligation (EVL) and ß-blockers±isosorbide mononitrate (ISMN) is currently recommended to prevent variceal rebleeding. However, the role of this combined therapy has been challenged by some studies. We performed a systematic review to assess the value of combined therapy with EVL and ß-blockers±ISMN as compared with ...
Balogh Emese - - 2013
Our objectives were to assess the frequency and sustainability of American College of Rheumatology (ACR)/European League against Rheumatism (EULAR) and Disease Activity Score (DAS)28(4v)-C-reactive protein (CRP) remission 12 months after the initiation of tumour necrosis factor inhibitor (TNFi) therapy in a rheumatoid arthritis (RA) cohort. Data were collected of 273 ...
Jain Kamini K Division of Child Health, School of Clinical Sciences, University of Nottingham, E Floor, East Block, Queen's Medical Centre, Derby Road, Nottingham, UK, NG9 - - 2013
Early diagnosis and treatment of lower respiratory tract infections, particularly those with Pseudomonas aeruginosa, are the mainstay of management of lung disease in cystic fibrosis. When sputum samples are unavailable, treatment relies mainly on cultures from oropharyngeal specimens; however, there are concerns regarding the sensitivity of these to identify lower ...
Jang Mi-Ok MO Department of Infectious - - 2013
There are no well-matched controlled studies comparing azithromycin with doxycycline for the treatment of complicated scrub typhus. A retrospective propensity-score-matched case-control study was performed for patients who presented with complicated scrub typhus and were treated with doxycycline or azithromycin between 2001 and 2011. Data on comorbidities, clinical manifestations, laboratory studies, ...
Parodi Guido G Department of Cardiology, Careggi Hospital, Florence, - - 2013
Aims: Subacute, late, and very late stent thrombosis (ST) may occur after stent implantation, but they are characterised by different underlying pathophysiological mechanisms. We sought to appraise differences between subacute and late/very late ST at the thrombus site by optical coherence tomography (OCT). The Mechanism Of Stent Thrombosis (MOST) study ...
Samadikhah Jahanbakhsh J Tabriz University of Medical Sciences, Tabriz, - - 2014
Purpose: Atrial fibrillation (AF) is the most frequent arrhythmia that follows coronary artery bypass graft (CABG). Patients developing postoperative AF (POAF) have significantly higher mortality rates. The consistent prophylactic effectiveness of statins and vitamin C are well-accepted; however, no evaluation on combined therapy has been performed. We aimed at assessing ...
Lakkireddy Dhanunjaya D Division of Cardiovascular Diseases, Cardiovascular Research Institute, Mid America Cardiology, University of Kansas Hospital & Medical Center, Kansas City, KS. Electronic address: - - 2013
The purpose of this study was to evaluate the feasibility and safety of uninterrupted rivaroxaban during atrial fibrillation (AF) ablation. Optimal periprocedural anticoagulation strategy is essential for minimizing bleeding and thrombo-embolic complications during and after AF ablation. The safety and efficacy of uninterrupted rivaroxaban as a periprocedural anticoagulant for AF ...
Pellicano Clelia - - 2013
Dopamine agonists (DA) are the first-choice drug for treatment of the early stage of Parkinson's disease (PD) in subjects younger than 70 years. Recently, a number of third generation DA have been marketed, including transdermal patch of rotigotine and extended release oral formulation of ropinirole and pramipexole.We investigated the impact ...
Pejcic Ana A Department of Periodontology and Oral Medicine, University of Nis, Nis, - - 2013
Objective: To evaluate the effect of periodontal treatment on gingival overgrowth in a group of renal transplant patients. Subjects and Methods: Twenty-five renal transplant recipients receiving immunosuppressive therapy with cyclosporine A (CsA) were randomly assigned to 2 groups. Group 1 (n = 15) included patients who had been specifically referred ...
Calzetti Stefano S Neurology Unit, Department of Neurosciences, Azienda Ospedaliero-Universitaria of Parma, Parma, Italy, - - 2013
It is currently controversial if and in which terms Parkinson's disease (PD) and restless legs syndrome (RLS) are linked in co-morbid association. In a cohort of 106 de novo PD patients (67 male and 39 female, aged 42-83 years), 15 of them developed RLS, which was prospectively assessed at 6-month intervals from ...
Duan Yun-Fei - - 2013
Hemostasis in thyroid surgery is of utmost importance for a successful surgery and an uneventful postoperative course. Our aim was to evaluate the effectiveness of the FOCUS Harmonic Scalpel in patients undergoing open total thyroidectomy. In this study, 778 patients were randomized into 2groups based on the surgical technique used: ...
Adravanti Paolo P Orthopaedic Surgery Department, Clinic "Città di Parma", Parma, - - 2013
It has been reported that even one year after total knee arthroplasty (TKA), a relevant percentage of patients does not attain complete recovery and indicate unfavourable long-term pain outcome. We compared the clinical outcome of 33 patients undergoing TKA randomly assigned to the control or the pulsed electromagnetic field group (I-ONE ...
Olanow C Warren CW Department of Neurology and Neuroscience, Mount Sinai School of Medicine, New York, NY, USA. Electronic address: - - 2014
Levodopa is the most effective therapy for Parkinson's disease, but chronic treatment is associated with the development of potentially disabling motor complications. Experimental studies suggest that motor complications are due to non-physiological, intermittent administration of the drug, and can be reduced with continuous delivery. We aimed to assess efficacy and ...
Cox Ruth J RJ Occupational Therapy Department, Princess Alexandra Hospital, - - 2013
The use of support workers such as occupational therapy assistants is emerging as a strategy to enhance the health workforce, but there has been little evaluation of the feasibility of expanding support worker roles and responsibilities. This study aimed to implement an advanced occupational therapy assistant-led groups programme in a ...
Notarnicola Angela A Course of Motor and Sports Sciences, Faculty of Medicine and Surgery, University of Study of Bari, Lungomare Starita 1, 70123, Bari, Italy, - - 2013
The application of laser therapy on soft tissue is used for pain relief, anti-inflammation action and biostimulation. The efficiency of High Energy Laser Therapy has not yet been studied on Achilles tendinopathy. The aim of the study is to evaluate the effectiveness of a flow of Cold air and High ...
Chang Shang-Hung SH 1Section of Cardiology, Chang Gung Memorial Hospital, Taoyuan, - - 2013
Clinical predictors of long-term outcomes in patients with critical limb ischemia (CLI) treated with endovascular therapy (EVT) remain unclear. In this study, clinical predictors of long-term outcomes in EVT-treated patients with CLI were investigated. In this prospective, observational study, we analyzed a total of 253 Taiwanese patients with CLI with ...
Seker Ahmet A 1Department of General Surgery, Faculty of Medicine, Harran University , Sanlıurfa , - - 2013
ABSTRACT Background: Radiation therapy is an essential therapeutic modality in the management of a wide variety of tumors. We aimed to investigate the short-term effects of pelvic irradiation on the healing of colon anastomoses and to determine the potential protective effects of β-glucan in this situation. Material and Methods: Sixty ...
Pasquale Timothy R - - 2013
Background: Methicillin-resistant Staphylococcus aureus (MRSA) is a common nosocomial pneumonia (NP) pathogen in US ICUs. Ceftaroline fosamil is a novel cephalosporin with activity against MRSA. Methods: We retrospectively reviewed patients (pts) who received ceftaroline therapy for MRSA NP. Results: A total of 10 pts received ceftaroline from September 2011 to ...
Brugada Josep J Hospital Clinic, University of Barcelona, Barcelona, Spain. Electronic address: - - 2014
Although cardiac resynchronization therapy (CRT) is effective in most patients with heart failure (HF) and ventricular dyssynchrony, a significant minority of patients (approximately 30%) are non-responders. Optimal atrioventricular and interventricular delays often change over time and reprogramming these intervals might increase CRT effectiveness. The SonR algorithm automatically optimizes atrioventricular and ...
Daniel Elbirt E Clinical Immunology, Allergy and AIDS Center Kaplan Medical Center, Affiliated with Hadassah-Hebrew University Medical School Jerusalem, Rehovot, - - 2013
IntroductionIn Israel, highly active antiretroviral therapy is available (at local pharmacies) without cost. Nevertheless, poor adherence, especially of immigrants from Africa, leads to high rate of treatment failures. Our study looked whether direct monthly highly active antiretroviral therapy supply in our AIDS center has an effect on adherence and outcome.MethodsA ...
Sanders-van Wijk Sandra S 1Maastricht University Medical Center, CARIM, Maastricht, the - - 2013
-Therapy guided by N-terminal-proB-type natriuretic peptide (NT-proBNP) levels may improve outcomes in patients with chronic heart failure (HF), especially in younger patients with reduced left-ventricular ejection fraction (LVEF). It remains unclear whether treatment effects persist after discontinuation of the NT-proBNP guided treatment strategy. -TIME-CHF randomized 499 HF patients aged ≥60years ...
Mortimer Alex M AM Department of Neuroradiology, Frenchay Hospital; Bristol, United Kingdom - - - 2013
This is a literature review on to the use of endovascular therapy in hyperacute ischaemic stroke secondary to large vessel occlusion (LVO). The prognosis for LVO is generally poor and the efficacy of intravenous tissue plasminogen activator (IV TPA) in the treatment of this subtype of stroke is questionable. It ...
Hadji P P Department of Gynecology, Endocrinology and Oncology, Philipps University of Marburg, - - 2013
This prospective study evaluated the relationship between arthralgia and compliance during the first year of adjuvant anastrozole therapy in postmenopausal women with hormone receptor-positive early breast cancer. COMPliance and Arthralgia in Clinical Therapy (COMPACT) was an open-label, multicenter, noninterventional study conducted in Germany. Patients had started adjuvant anastrozole 3-6 months ...
Feres Fausto F Instituto Dante Pazzanese de Cardiologia, São Paulo, São Paulo, - - 2013
The current recommendation is for at least 12 months of dual antiplatelet therapy after implantation of a drug-eluting stent. However, the optimal duration of dual antiplatelet therapy with specific types of drug-eluting stents remains unknown. To assess the clinical noninferiority of 3 months (short-term) vs 12 months (long-term) of dual ...
Yamamoto Takayuki T Inflammatory Bowel Disease Center, Yokkaichi Social Insurance Hospital, 10-8 Hazuyamacho, Yokkaichi, Mie, 510-0016, Japan, - - 2013
This prospective study was to evaluate the significance of fecal calprotectin and lactoferrin for the prediction of ulcerative colitis (UC) relapse. Eighty UC patients in remission for ≥3 months on mesalamine as maintenance therapy were included. At entry, stool samples were collected for the measurement of calprotectin and lactoferrin. All patients ...
Ko D-Y DY Department of Dermatology, Skin Cancer Center, College of Medicine, Dong-A University, Busan, - - 2013
Photodynamic therapy (PDT) with methyl aminolevulinate (MAL) is effective for treating multiple actinic keratoses (AKs). Ablative fractional laser (FL) creates vertical channels that may facilitate MAL delivery and improve PDT response. To evaluate the efficacy of FL-assisted PDT (FL-PDT) in treating facial AKs in Korean patients. A prospective randomized non-blinded ...
Bouguen Guillaume G *Division of Gastroenterology, University of California San Diego, San Diego, California; and †Department of Hepato-Gastroenterology, University Hospital of Rennes, Pontchaillou, Inserm U991 University of Rennes 1, Rennes, - - 2013
Mucosal healing (MH) as a treatment target for ulcerative colitis is of growing interest because it is associated with improved clinical outcomes. However, the feasibility and probability of reaching MH in clinical practice is unknown. We therefore evaluated the feasibility of "treating to target" according to endoscopic findings to reach ...
Russo Ricardo A G RA Department of Rheumatology, UCL Institute of Child Health and Great Ormond Street Hospital NHS Foundation Trust, National Amyloidosis Centre, UCL Medical School, Royal Free Campus and Department of Audiology, Great Ormond Street Hospital NHS Foundation Trust, London, - - 2013
Objective. The aim of this study was to determine the short- and long-term efficacy and safety of 8-weekly canakinumab therapy in children with cryopyrin-associated periodic syndromes (CAPS) in routine clinical practice.Methods. A single-centre observational study was performed. Patients were assessed every 8 weeks at a dedicated clinic. Standardized assessments were ...
Kalita Jayantee J Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, - - 2013
Background: Penicillamine is a standard therapy for Wilson disease (WD) but some patients have paradoxical worsening. Predictors of such deterioration have not been evaluated. This study documents frequency and predictors of deterioration following treatment in WD. Methods: 59 consecutive patients with neurologic WD and 4 asymptomatic siblings were prospectively evaluated. ...
Pandit Anil A Division of Cardiovascular Diseases, Mayo Clinic, Scottsdale, Arizona, USA. Electronic address: - - 2013
To review efficacy of percutaneous closure of patent foramen ovale compared with medical therapy in prevention of recurrent strokes in patients with cryptogenic stroke. Electronic databases; PUBMED, EMBASE, Cochrane registry and web of knowledge were searched for relevant studies. In three randomised clinical trials involving 2303 participants, risk of the ...
Kim Mi Na MN Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea; Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea; Liver Cirrhosis Clinical Research Center, Seoul, - - 2013
We examined the durability of the virological response after discontinuing lamivudine (LVD) in chronic hepatitis B (CHB) patients with LVD-resistant hepatitis B virus (HBV), who responded to LVD plus adefovir (ADV) combination therapy, and the outcome of switching to ADV monotherapy compared to maintaining combination therapy. The study enrolled 72 ...
Merlo Marco M Cardiovascular Department, Ospedali Riuniti and University of Trieste, Trieste, 34149, - - 2013
ACE-inhibitors, β-blockers, implantable cardioverter-defibrillator (ICD) and cardiac resynchronization therapy (CRT) improved prognosis of heart failure. We sought to analyse the long-term prognostic impact of evidence-based integrated therapeutic strategies in patients with idiopathic dilated cardiomyopathy (IDCM). From 1978 to 2007, 853 IDCM patients (45 ± 15 years, 72% males) were enrolled and classified as ...
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