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Results 401 - 450 of 4747
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Scarano Antonio A From the *Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Chieti, Italy; †Department of Oral Rehabilitation, School of Dental Medicine, Tel-Aviv University, Israel; and ‡Department of Medical Science, Faculty of Medicine, University of Eastern Piedmont, Novara, - - 2014
The aim of this study was to evaluate the use of calcium sulfate (CaS) as a hemostatic agent after tooth extraction in patients with anticoagulant drug therapy.A total of 30 patients undergoing anticoagulant therapy (22 women and 8 men) with a mean age of 54.6 years (SD = 9.2 years), ...
Leow O M - - 2014
This study aimed to evaluate the efficacy and safety of intra-articular glucocorticoid (IAG) injections in our institution in children with juvenile idiopathic arthritis (JIA). This is a retrospective assessment of IAG injections performed by the Department of Paediatrics, National University Hospital, Singapore, from October 2009 to October 2011. A total ...
Liberini P P Division of Neurology, Brescia General Hospital, Piazza Spedali Civili 1, Brescia, Italy, - - 2014
In 2013 the Italian Pharmacy Agency (AIFA) approved onabotulinumtoxin A injection to prevent headaches in adult patients with chronic migraine (headaches on at least 15 days per month of which at least 8 days are with migraine) that has not responded to at least three prior pharmacological prophylaxis therapies and whose condition ...
Chedid Victor V University of Pittsburgh Medical Center, Department of Internal Medicine, Pittsburgh, Pennsylvania (Dr Chedid), United - - 2014
Patients with small intestine bacterial overgrowth (SIBO) have chronic intestinal and extraintestinal symptomatology which adversely affects their quality of life. Present treatment of SIBO is limited to oral antibiotics with variable success. A growing number of patients are interested in using complementary and alternative therapies for their gastrointestinal health. The ...
Bron Morgan M Takeda Pharmaceuticals International, Inc., Deerfield, - - 2014
Current type 2 diabetes mellitus (T2DM) treatment involves progressive interventions from lifestyle changes to pharmacological therapies. Previous studies found that combination therapy with a dipeptidyl peptidase-4 inhibitor (DPP-4i) and pioglitazone (PIO) is more effective than monotherapies in treating poorly controlled T2DM, but there is no consensus on whether these drugs ...
Cerezo-Manchado Juan Jose JJ Hospital Universitario Morales Meseguer & Centro Regional de Hemodonacion, University of Murcia, Ronda de Garay s/n, 30003, IMIB, Murcia, - - 2014
Aim: To analyze VKORC1, CYP2C9 and CYP4F2 polymorphisms in relation to the main outcomes in the first stages of acenocoumarol therapy. Patients & methods: Nine hundred and forty one patients who had started therapy and in whom time to stable dosage, time to over-anticoagulation and adverse events occurred during 3 ...
Akcan Alper A Department of General Surgery, Erciyes University School of Medicine, Kayseri, - - 2014
Idiopathic granulomatous mastitis (IGM) is an uncommon chronic inflammatory disease of the breast with uncertain optimal treatment regimen. In this study, our purpose was to report our clinical experience with 74 IGM patients who were treated wide local excision with or without steroid therapy. 74 cases diagnosed histologically as IGM ...
Sharifi Seyed Hossein Hosseini SH Shahid Labbafinejad Medical Center, Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, I.R. - - 2014
Objective: To compare the safety and efficacy of combined therapy using sildenafil and tamsulosin for management of acute urinary retention (AUR) with tamsulosin alone in patients with benign prostate hyperplasia (BPH). Materials and Methods: 101 patients were enrolled in a randomized placebo-controlled study from June 2009 to April 2012. Patients ...
Falahatkar Siavash S Urology Research Center, Razi Hospital, Guilan University of Medical - - 2014
Objective: To compare the outcomes of bipolar transurethral vaporization of the prostate (TUVP) with bipolar transurethral resection of the prostate (TURP). Materials and Methods: In a prospective randomized trial, 88 patients with moderate to severe lower urinary tract symptoms secondary to benign prostatic hyperplasia (BPH) underwent bipolar TUVP (N = ...
de Jong P H PH Department of Rheumatology, University Medical Center, Rotterdam, The - - 2014
To compare 1-year clinical efficacy of (1) initial triple disease-modifying antirheumatic drug therapy (iTDT) with initial methotrexate (MTX) monotherapy (iMM) and (2) different glucocorticoid (GC) bridging therapies: oral versus a single intramuscular injection in early rheumatoid arthritis. In a single-blinded randomised clinical trial patients were randomised into three arms: (A) ...
Baros Duka Ninković - - 2014
Psoriasis is a chronic, inflammatory, immune-mediated skin disease. In addition to standard therapeutic modalities (antibiotics, cytostatics, phototherapy, photochemotherapy and retinoids), nonstandard methods can be used in the treatment of psoriasis. This includes balneotherapy which is most commonly used in combination with therapeutic resources. The aim of this research was to ...
Nguyen Harrison P HP Baylor College of Medicine, Houston, - - 2014
Infantile hemangiomas (IH) are common benign vascular tumors seen in children. Although the majority will improve spontaneously without treatment, a small subset will require therapy due to a variety of complications. Less than a decade ago, propranolol replaced corticosteroids as first-line treatment for most IH and it has proven to ...
Marenzi Giancarlo G Centro Cardiologico Monzino, I.R.C.C.S., Milan, Italy. - - 2014
Background: There are limited data comparing ultrafiltration with standard medical therapy as first-line treatment in patients with severe congestive heart failure (HF). We compared ultrafiltration and conventional therapy in patients hospitalized for HF and overt fluid overload.Methods and Results: Fifty-six patients with congestive HF were randomized to receive standard medical ...
Gupta Prashant P Department of Oral Medicine and Radiology, Peoples University, Bhopal, Madhya Pradesh, - - 2014
The study was designed to evaluate the serum interleukin-8 (IL-8) levels in patients with recurrent aphthous ulcer (RAU) and monitor the immunomodulation and altered IL-8 levels by levamisole before therapy and after levamisole therapy. This study was carried as a randomized case-control study involving a study group of 30 patients ...
Gompelmann Daniela D Pneumology and Critical Care Medicine, Thoraxklinik, University of Heidelberg, and Translational Research Center Heidelberg, Member of the German Center for Lung Research, Heidelberg, - - 2014
Background: Patients who achieve significant target lobe volume reduction (TLVR) following endobronchial valve (EBV) treatment may experience substantial improvements in clinical outcome measures. However, in cases of rapid TLVR, the risk of pneumothorax increases due to parenchymal rupture of the adjacent untreated lobe. Target lobe collapse may be more likely ...
Min Yang Won YW Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, - - 2014
The occurrence of gastroesophageal reflux disease (GERD) is known to be associated with lower post-treatment lower esoph-ageal sphincter pressure in patients with achalasia. This study aimed to elucidate whether GERD after pneumatic balloon dilata-tion (PD) has a prognostic role and to investigate how the clinical course of GERD is. A ...
van Zeller Mafalda M Drs van Zeller and Almeida and Ms Eusébio are affiliated with the Department of Pulmonology, Centro Hospitalar de São João, Porto, - - 2014
Treatment adherence is widely recognized as a critical problem in long-term oxygen therapy, particularly in ambulatory liquid oxygen (LOX) systems. Adherence-monitoring strategies may be helpful in managing patients. We evaluated subjects' adherence to LOX using VisionOx and compared these results with the subjects' own adherence diaries and self-reported perceptions of ...
Zeisberg A A Department of Ophthalmology, Charité University Medicine Berlin, Campus Benjamin Franklin, 12200, Berlin, - - 2014
The aim of this retrospective study was to determine the efficacy of proton beam irradiation in choroidal hemangioma in a long-term follow-up. A total dose of 20 Cobalt Gray equivalent (CGE) was administered to 50 eyes of 50 patients from September 1998 to September 2010. All treated patients presented with ...
Varkonyi Istvan I Kenezy Gyula Hospital and Outpatient Facility, Debrecen, - - 2014
We completed a prospective study of 164 patients involved in a Clostridium difficile surveillance program, evaluating a range of variables such as disease severity, treatment regimen, and known clinical risk factors, for their effect on case lethality. The aim of this study was to determine if there are any additional ...
Yeon Gyu-Min GM 1 Department of Pediatrics, College of Medicine, Kosin University , Busan, - - 2014
Abstract Objective: Few studies have been conducted among pediatric patients to examine clinical outcomes associated with the combined use of Oriental medicine and other therapies to treat epilepsy. The purpose of this study was to examine the clinical and laboratory characteristics of children with epilepsy being treated with traditional Korean ...
Yang Na Rae NR Department of Neurosurgery, Ewha Womans University School of Medicine, Mokdong Hospital, 911-1 Mok-dong, Yangcheon-gu, Seoul, 158-710, - - 2014
Problems that the risk of using antiplatelet/anticoagulant may overwhelm its benefits have been raised. We analyzed patients with spontaneous intracerebral hemorrhage who had received antiplatelet/anticoagulant therapy. A consecutive series of patients with spontaneous intracerebral hemorrhage who underwent brain computed tomographic (CT) scans within 48 h from attack. We analyzed the clinical ...
Flury Baharak Babouee - - 2014
Vertebral osteomyelitis (VO) may lead to disabling neurologic complications. Little evidence exists on optimal antibiotic management. All patients with primary, non-implant VO, admitted from 2000-2010 were retrospectively analyzed. Patients with endocarditis, immunodeficiency, vertebral implants and surgical site infection following spine surgery were excluded. Persistence of clinical or laboratory signs of ...
Song Gi-Won GW 1 Division of Liver Transplantation and Hepatobiliary Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. 2 Address correspondence to: Sung-Gyu Lee, M.D., F.A.C.S., 388-1 Pungnab2-dong, Songpa-gu, Seoul, - - 2014
The use of rituximab (Rit) to prevent antibody-mediated rejection (AMR) of ABO-incompatible (ABOi) adult living donor liver transplants (ALDLTs) has raised questions about the role of local graft infusion therapy (LGIT) and splenectomy (SPN); however, they are still regarded as essential components of the desensitization (DSZ) protocol. The DSZ protocol ...
Mizobe Michio M Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, - - 2014
The aim of this study was to examine the impact of CYP2C19 genotype on clinical outcome in coronary artery disease (CAD) patients with or without diabetes mellitus (DM). CYP2C19 polymorphism and DM are associated with increased risk of cardiovascular events during antiplatelet therapy following stent implantation. Platelet reactivity during clopidogrel ...
Kanji Hussein D HD Department of Critical Care Medicine, University of British Columbia; Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, - - 2014
The purpose of the study was to compare the effect of limited echocardiography (LE)-guided therapy to standard management on 28-day mortality, intravenous fluid prescription, and inotropic dosing following early resuscitation for shock. Two hundred twenty critically ill patients with undifferentiated shock from a quaternary intensive care unit were included in ...
Morgan C Ll CL Global Epidemiology, Pharmatelligence, Cardiff, - - 2014
To compare the risk of major adverse cardiovascular events (MACE) and mortality for combination therapies with metformin and either sulfonylurea (SU) or DPP-4 inhibitor (DPP-4i). Data were from the UK Clinical Practice Research Datalink (CPRD). Patients with type 2 diabetes were selected if initiated with combination therapies comprising metformin plus ...
Sulz Michael C MC Department of Gastroenterology and Hepatology, Kantonspital St. Gallen, - - 2014
Hemospray (Cook Medical, Winston-Salem, North Carolina, USA) is a hemostatic agent recently introduced for the management of upper gastrointestinal bleeding (GIB). To date, there is little experience with this fairly new hemostatic tool. The aim of this case series was to reflect the use and effectiveness of Hemospray as a ...
Cahn Pedro P Clinical Research Department, Fundación Huésped, Buenos Aires, Argentina. Electronic address: - - 2014
Daily oral triple therapy is effective at halting HIV disease progression, but can have toxic effects and is costly. We investigated whether dual therapy with lopinavir and ritonavir plus lamivudine is non-inferior to standard triple therapy. The GARDEL study (Global AntiRetroviral Design Encompassing Lopinavir/r and Lamivudine vs LPV/r based standard ...
Schroeder A S AS Department of Paediatric Neurology and Developmental Medicine, Hauner Children's Hospital, University of Munich, Germany; German Center for Vertigo and Balance Disorders, IFB(LMU), University of Munich, Germany. Electronic address: - - 2014
Robot-enhanced therapies are increasingly being used to improve gross motor performance in patients with cerebral palsy. To evaluate gross motor function, activity and participation in patients with bilateral spastic cerebral palsy (BS-CP) after Robot-enhanced repetitive treadmill therapy (ROBERT) in a prospective, controlled cohort study. Participants trained for 30-60 min in each of ...
Chon Min Ku MK Division of Cardiology, Department of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan, - - 2014
Pulmonary thromboembolism (PTE) is a common clinical condition related to significant mortality. Furthermore, patients with PTE presenting with right heart thrombus show higher mortality due to rapid hemodynamic deterioration. But the optimal treatment of massive PTE is controversial although various methods have been developed and improved. Here, we presented a ...
Vinayagam S S Katharine Dormandy Haemophilia Centre & Thrombosis Unit, Royal Free London NHS Foundation Trust, London, United - - 2014
Haemostatic management of surgery in patients with von Willebrand disease (VWD) includes DDAVP(®) or von Willebrand factor (VWF)-containing concentrates. Although the recommendations are for monitoring by VWF activity assays, it is quite common for clinicians to use factor VIII due usually to longer turnaround times required for VWF ristocetin cofactor ...
Ray Kathryn J KJ F. I. Proctor Foundation, University of California, San Francisco2Department of Epidemiology and Biostatistics, University of California, San - - 2014
IMPORTANCE Scarring from bacterial keratitis remains a leading cause of visual loss. OBJECTIVE To determine whether topical corticosteroids are beneficial as an adjunctive therapy for bacterial keratitis if given early in the course of infection. DESIGN, SETTING, AND PARTICIPANTS The Steroids for Corneal Ulcers Trial (SCUT) was a randomized, double-masked, ...
Kurita Takashi T Division of Rheumatology, Endocrinology and Nephrology, Hokkaido University Graduate School of Medicine and Translational Research and Clinical Trial Center, Hokkaido University Hospital, Sapporo, - - 2014
Objective. Interstitial lung diseases (ILDs) complicated with PM or DM are frequently aggressive and refractory to treatment. Recently some reports have suggested the potential benefit of tacrolimus for severe ILD complicated with PM/DM. However, little evidence has yet shown the efficacy of tacrolimus in these settings. The aim of this ...
Aoki Jiro J Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan. Electronic address: - - 2014
The endothelial progenitor cell (EPC) plays an important role in repairing vascular injury. Statins and angiotensin II receptor blockers increase the level of circulating EPCs. However, it is unknown whether the angiotensin II receptor blocker olmesartan synergistically acts with statins to increase the levels of circulating EPCs. Moreover, the association ...
Stucky C-C H CC Department of General Surgery, Mayo Clinic Arizona, 5777 E. Mayo Boulevard, Phoenix, AZ, 85054, - - 2014
Previous reports document the safety of open inguinal herniorrhaphy in patients on chronic warfarin therapy; however, the practice remains controversial. This study is a 10-year update of our experience. A retrospective review of 1,839 consecutive patients undergoing open inguinal hernia repair was conducted from 2000 to 2010. All patients on ...
Hernández Domingo - - 2014
Left ventricular hypertrophy (LVH) is common in kidney transplant (KT) recipients. LVH is associated with a worse outcome, though m-TOR therapy may help to revert this complication. We therefore conducted a longitudinal study to assess morphological and functional echocardiographic changes after conversion from CNI to m-TOR inhibitor drugs in nondiabetic ...
Liang Zhihui Z Department of Radiology, Bethune International Peace Hospital, Zhongshan West Road 398, Shijiazhuang, 050082, Hebei, - - 2014
To evaluate the role of filter implantation in reducing the incidence of fatal pulmonary embolism during the endovascular treatment of thrombosis in the major tributary of the superior vena cava (SVC). From October 2004 to October 2008, we conducted a cohort study of 40 patients with thrombosis of the central ...
Steinberg Benjamin A BA Duke Center for Atrial Fibrillation, Durham, NC, - - 2014
Atrial fibrillation (AF) and coronary artery disease (CAD) are common in older patients. We aimed to describe the use of antiarrhythmic drug (AAD) therapy and clinical outcomes in these patients.METHODS AND RESULTS: We analysed AAD therapy and outcomes in 1738 older patients (age ≥65) with AF and CAD in the ...
Nishida Tsutomu T Tsutomu Nishida, Masahiko Tsujii, Hideki Iijima, Tetsuo Takehara, Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, - - 2014
To evaluate the efficacy and safety of esomeprazole-based triple therapy compared with lansoprazole therapy as first-line eradication therapy for patients with Helicobacter pylori (H. pylori) in usual post-marketing use in Japan, where the clarithromycin (CAM) resistance rate is 30%. For this multicenter, randomized, open-label, non-inferiority trial, we recruited patients (≥ ...
Westendorp Willeke F - - 2014
Stroke is a leading cause of death worldwide. Infections after stroke occur in 30% of stroke patients and are strongly associated with unfavourable outcome. Preventive antibiotic therapy lowers infection rate in patients after stroke, however, the effect of preventive antibiotic treatment on functional outcome after stroke has not yet been ...
Stabile Eugenio E Department of Advanced Biomedical Sciences, University of Napoli "Federico II", Napoli, Italy. Electronic address: - - 2014
Common clinical practice recommends dual antiplatelet therapy (DAPT) for transcatheter aortic valve implantation (TAVI). The aim of the study was to evaluate, in a double blind randomized study, the safety of TAVI, with adjunctive pharmacotherapy consisting of single antiplatelet therapy. From April 2010 to April 2011, 120 consecutive patients, undergoing ...
Shi Yongjun Y Department of Gastroenterology, Provincial Hospital Affiliated to Shandong University, 324 Jingwu Weiqi Road, Jinan, 250021, Shandong, People's Republic of China, - - 2014
Transjugular intrahepatic portosystemic shunt (TIPS) with adjunctive embolotherapy has recently been reported to be effective in the prevention of variceal hemorrhage of cirrhotic patients. However, further investigation of its long-term efficacy is still needed. To examine the rebleeding, survival, and hepatic encephalopathy (HE) after treatment with TIPS alone and TIPS ...
Liu Chen-Hua CH Department of Internal Medicine, National Taiwan University Hospital, , Taipei, - - 2014
Data comparing the efficacy and safety of combination therapy with peginterferon plus low-dose ribavirin and peginterferon monotherapy in treatment-naive haemodialysis patients with hepatitis C virus genotype 2 (HCV-2) infection are limited. In this randomised trial, 172 patients received 24 weeks of peginterferon alfa-2a 135 μg/week plus ribavirin 200 mg/day (n=86) ...
Haanschoten Marco C MC Department of Anesthesiology, Intensive Care Unit, Catharina Hospital, Eindhoven, The Netherlands; Intensive Care Unit, Catharina Hospital, Eindhoven, The - - 2014
In the present study, we investigated the survival of patients who received postoperative renal replacement therapy (RRT) after cardiac surgery. We specifically focused on factors predicting long-term outcome in elderly patients. Data of all patients that received unintentional renal replacement therapy following cardiac surgery between 2004 and 2010 were analyzed. ...
Yang Ten-Fang TF Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu, Taiwan; Graduate Institute of Biomedical Informatics, Taipei Medical University and Evidence Based Medicine Center, Taipei Medical University Hospital, Taipei, - - 2014
The aim of our study was to determine whether pre-emptive statin therapy was associated with improved outcome of infective endocarditis (IE). We conducted a nationwide, population-based, propensity score-matched cohort study with the Taiwan's National Health Insurance Research Database. All patients with IE between January 2000 and December 2010 were enrolled. ...
Farkas Klaudia K First Department of Medicine, University of Szeged, 8-10 Koranyi fasor, Szeged, H6720, - - 2014
To date, corticosteroids have been the primary therapies for acute, severe ulcerative colitis (UC). Patients not responding to intravenous steroids assessed at 3-5 days of the treatment are candidates for second-line rescue therapy. Cyclosporine (CsA), tacrolimus and infliximab (IFX) are also effective therapeutic options in acute, severe UC. In this ...
Sheu Jiunn-Jye - - 2014
We tested the hypothesis that clopidogrel and cilostazol combination therapy could effectively attenuate systemic inflammatory reaction, facilitate proliferation of circulating endothelial progenitor cell (EPC), and improve the clinical outcomes of critical limb ischemia (CLI) in patients unsuitable for surgical revascularization or percutaneous transluminal angioplasty (PTA). A total 55 patients (mean ...
Warshauer Jeremy J VA North Texas Healthcare System and University of Texas Southwestern Medical Center, Dallas, Texas, - - 2014
Background: Preoperative bridging with a glycoprotein IIb/IIIa inhibitor is often performed in patients with prior coronary stents undergoing surgery who require antiplatelet therapy discontinuation, but its safety and efficacy have received limited study. We performed a weighted meta-analysis of the outcomes in patients with coronary stents undergoing bridging with glycoprotein ...
Kim Na Young NY Department of Anesthesiology and Pain Medicine, Yonsei University College of - - 2014
Background: Preoperative fibrinogen concentration is associated with increased blood loss at the lower end, and with hypercoagulability-related ischemic event at the higher end in cardiac patients. We evaluated the influence of preoperative fibrinogen concentration on blood loss and outcome in patients who received clopidogrel in proximity to off-pump coronary artery bypass ...
Alpak Gokay G Department of Psychiatry, Gaziantep University, School of Medicine, Gaziantep, - - 2014
Objective: To investigate the effects of recurrent electroconvulsive therapy (ECT) on cardiac function as assessed by echocardiography. Subjects and Methods: Twenty-three patients (11 males and 12 females) with different psychiatric disorders who were apparently free of any cardiovascular disorders and underwent ECT were enrolled in the study. Echocardiographic findings including ...
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