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Results 301 - 350 of 4748
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Verstraelen F U FU Viecuri Medical Centre, Tegelseweg 210, 5912 BL, Venlo, The Netherlands, - - 2014
There are several treatment options for calcifying tendinitis of the shoulder. The next step treatment after conservative treatment fails is still a matter of dispute. Extracorporeal shock wave therapy (ESWT) has been shown to be a good alternative to surgery, but the best treatment intensity remains unknown. High-energy ESWT is ...
Vorhies Erika E EE Division of Pediatric Cardiology, Department of Pediatrics, University of Calgary, Alberta Children's Hospital, 2888 Shaganappi Trail NW, Calgary, AB, T3B 6A8, Canada, - - 2014
Inhaled nitric oxide (iNO) is considered standard therapy for pediatric postcardiac surgical pulmonary hypertension (PH). Limited data suggest that inhaled iloprost (inIlo), an aerosolized prostacyclin, may be a feasible and more affordable therapeutic alternative. The goal of this study was to determine if significant hemodynamic change or adverse events would ...
Giehl Kathrin A KA Department of Dermatology and Allergology Ludwig-Maximilian University Munich Frauenlobstr. 9-11 80337 Munich, - - 2014
Background: Photodynamic therapy (PDT) using 5-aminolevulinic acid (ALA) with red light is well established for actinic keratosis (AK). Differences have been observed concerning pain and efficacy rates with different red light sources. Objectives: To compare pain scores, short- and long-term efficacy rates of PDT of multiple AKs when employing different ...
Chua Horng-Ruey HR Department of Intensive Care, Austin Hospital, Melbourne, Australia; Division of Nephrology, Department of Medicine, National University Hospital, National University Health System, - - 2014
The risk of catheter-related infection or bacteremia, with initial and extended use of femoral versus nonfemoral sites for double-lumen vascular catheters (DLVCs) during continuous renal replacement therapy (CRRT), is unclear. Retrospective observational cohort study. Critically ill patients on CRRT in a combined intensive care unit of a tertiary institution. Femoral ...
Mastropasqua Rodolfo R Ophthalmology Unit Department of Neurological Neuropsychological Morphological and Movement Sciences, University of Verona, Verona, - - 2014
To analyze, using in vivo laser scanning confocal microscopy (LSCM), the conjunctival features in glaucomatous patients receiving prostaglandin analogues (PGA). Eighty eyes of 80 consecutive glaucomatous patients naive for therapy were enrolled; 30 eyes of 30 healthy subjects served as a control. Patients were randomized to: preservative-free (PF) and preserved ...
Tagami Takashi T Department of Emergency and Critical Care Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan, - - 2014
Although prophylactic triple-H therapy has been used in a number of institutions globally to prevent delayed cerebral ischemia (DCI) after subarachnoid hemorrhage (SAH), limited evidence is available for the effectiveness of triple-H therapy on hemodynamic variables. Recent studies have suggested an association between low global end-diastolic volume index (GEDI), measured ...
De Caridi Giovanni G Cardiovascular and Thoracic Department, 'Policlinico G. Martino' Hospital, University of Messina, Messina, - - 2014
Vacuum-assisted closure (VAC) therapy is a new emerging non-invasive system in wound care, which speeds up wound healing by causing vacuum, improving tissue perfusion and suctioning the exudates, and facilitating the removal of bacteria from the wound. The application of sub-atmospheric pressure on the lesions seems to alter the cytoskeleton ...
Turner DeAnna W DW University Health System, San Antonio, TX, USA University of the Incarnate Word Feik School of Pharmacy, San Antonio, TX, - - 2014
During respiratory and metabolic acidosis, the vasoconstrictive effects of epinephrine may be blunted, whereas the response to vasopressin remains unchanged. The impact of this effect during advanced cardiac life support (ACLS) remains unclear. Determine if vasopressin therapy in combination with epinephrine was associated with improved outcomes in patients with cardiac ...
Takebayashi Takashi T Department of Rehabilitation, The Hospital of Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan. Electronic address: - - 2014
Botulinum toxin type A (BtxA) injection, constraint-induced movement therapy (CIMT) and robotic therapy (RT) each represent promising approaches to enhance arm motor recovery after stroke. To provide more effective treatment for a 50-year-old man with severe left spastic hemiparesis, we attempted to facilitate CIMT with adaptive approaches to extend the ...
Galland-Girodet Sigolène S Department of Radiation Oncology, Massachusetts General Hospital, Boston, - - 2014
To present long-term outcomes of a prospective feasibility trial using either protons or 3-dimensional conformal photon-based (accelerated partial-breast irradiation [APBI]) techniques. From October 2003 to April 2006, 98 evaluable patients with stage I breast cancer were treated with APBI (32 Gy in 8 fractions given twice daily) on a prospective clinical trial: ...
Wang Q Q Shandong Provincial Hospital affiliated to Shandong University, Jinan, - - 2014
Hypogonadotropic hypogonadism (HH) is common in pituitary stalk interruption (PSI) patients. However, the optimal timing and effective regimen in the management of the pituitary-gonadal axis deficiency is still controversial. This study involved a retrospective review of 38 male patients with HH resulting from PSI. The HH patients were subdivided according ...
Cutro Scott R SR Division of Infectious Diseases, New York University School of Medicine, New York, New York, USAThe Southeast Permanente Medical Group, Atlanta, Georgia, USA - - 2014
Piperacillin-tazobactam (PTZ) is frequently used as both empiric and targeted therapy for Gram-negative sepsis. Time-dependent killing properties of PTZ support the use of extended-infusion (EI) dosing, however studies have shown inconsistent benefits of EI PTZ on clinical outcomes. We performed a retrospective cohort study of adult patients who received EI ...
Garanito Marlene Pereira MP Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, SP, Brazil. Electronic address: - - 2014
to evaluate the outcome of children with severe acquired aplastic anemia treated with rabbit antithymocyte globulin and cyclosporine as first-line treatment at this institution. retrospective analysis of 26 pediatric patients with aplastic anemia, treated between 1996 and 2011 with rabbit antithymocyte globulin plus cyclosporine. the overall response rate at six ...
Sabino Flávio D FD Department of Abdominal and Pelvic Surgery, National Cancer Institute, Rio de Janeiro, Brazil; Department of General Surgery, Federal Hospital of Rio de Janeiro State Civil Servers, Rio de Janeiro, Brazil. Electronic address: - - 2014
The administration of intraperitoneal (IP) 5-fluorouracil (5-FU) during the early postoperative period after cytoreductive surgery can decrease local cancer recurrence but may also cause impairment of the anastomotic healing. This study examined the effects of the use of this therapy and of the anastomotic sealing with TachoSil, a fibrin-thrombin coated ...
Wang Yanhuang Y School and Hospital of Stomatology, Fujian Medical - - 2014
Enterococcus faecalis poses a challenge to the efficacy of traditional root canal disinfection methods. This study was aimed to establish a synergistic root canal disinfection strategy combining ultrasonic irrigation with photodynamic therapy (PDT) together and to test its antibacterial efficacy against E. faecalis. Twenty-seven bovine root canals infected with E. ...
Piaggesi Alberto A Diabetic Foot Section, Department of Medicine, Azienda Ospedaliero-Universitaria Pisana, Via Paradisa, Pisa, Italy - - 2014
We evaluated the safety and efficacy of sulodexide, a biocompound of glycosamin-glicans, as adjunct medical therapy to percutaneous transluminal angioplasty (PTA) in diabetes mellitus (DM) patients with critical limb ischemia (CLI). We studied 27 consecutive DM patients with CLI successfully subjected to PTA who, on top of standard antiplatelet therapy, ...
Marco Helena - - 2014
Rituximab is a B cell depleting anti-CD20 monoclonal antibody. CD20 is not expressed on mature plasma cells and accordingly rituximab does not have immediate effects on immunoglobulin levels. However, after rituximab some patients develop hypogammaglobulinaemia. We performed a single centre retrospective review of 177 patients with multisystem autoimmune disease receiving ...
La Torre Francesco - - 2014
Juvenile idiopathic arthritis is a relatively common chronic disease of childhood, and is associated with persistent morbidity and extra-articular complications, one of the most common being uveitis. The introduction of biologic therapies, particularly those blocking the inflammatory mediator tumor necrosis factor-alpha, provided a new treatment option for juvenile idiopathic arthritis ...
Stryjewski Martin E - - 2014
Staphylococcus aureus bacteremia is a common infection associated with significant morbidity and mortality. Telavancin is a bactericidal lipoglycopeptide active against Gram-positive pathogens, including methicillin-resistant S. aureus (MRSA). We conducted a randomized, double-blind, Phase 2 trial in patients with uncomplicated S. aureus bacteremia. Patients were randomized to either telavancin or standard ...
Malani Anurag N AN Department of Internal Medicine Section of Infectious - - 2014
 Voriconazole was 1 of 2 antifungal agents recommended for treatment of fungal infections associated with injection of contaminated methylprednisolone. Alopecia and nail changes are not commonly reported side effects of voriconazole. Having noted increasing hair loss among our patients treated with voriconazole, we sought to determine the prevalence and characteristics ...
Arnoldner Michael A MA *Ocular Surface Imaging Center, Massachusetts Eye and Ear Infirmary, Boston, MA; †Corneal and Refractive Surgery Service, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, MA; ‡Department of Ophthalmology, Cogan Pathology Laboratory, Massachusetts Eye and Ear Infirmary, Boston, MA; and §Department of Medicine, Division of Infectious Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, - - 2014
To report a case of successful medical treatment with oral posaconazole in refractory fungal keratitis caused by Paecilomyces lilacinus. Case report. A 57-year-old male, soft contact lens wearer presented with irritation, pain, photophobia, and reduced vision. Slit-lamp examination showed a large corneal epithelial defect with a peripheral infiltrate. The patient ...
Jaspers Aurélie A Department of Medicine, Division of Hematology, CHU of Liege and University of Liege, Liege, - - 2014
We conducted a prospective randomized trial to assess hemoglobin (Hb) response to recombinant human erythropoietin (rhEPO) therapy after hematopoietic cell transplantation (HCT). Patients (n=131) were randomized (1:1) between no treatment (control arm) or erythropoietin (Neorecormon®) at 500 U/kg/week (EPO arm). Patients were also stratified in 3 cohorts: patients undergoing myeloablative ...
Florescu Cosmin C Diagnostic Imaging, Monash Health, Melbourne, Victoria, - - 2014
The literature suggests that endovenous laser is less efficacious in great saphenous veins (GSVs) with a diameter of greater than 1 cm. This paper describes the efficacy of endovenous laser therapy (EVLT) in ablating GSV with a diameter greater than 1.0 cm. Retrospective review of consecutive patients undergoing GSV EVLT between 15 ...
Nomura Hideyuki H The Center for Liver Disease, Shin-kokura Hospital, Kitakyushu, Japan. Electronic address: - - 2014
This study aims to evaluate the efficacy and safety of interferon-beta plus ribavirin therapy in older Japanese patients. This study enrolled 132 older patients (age, ≥65 years) with chronic hepatitis C who received 24-48 weeks of interferon-beta plus ribavirin (FR; n = 66) or pegylated interferon-alpha plus ribavirin (PR; n = 66) therapy. Patients ...
Nenu Iuliana I Department of Physiology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 1 Clinicilor Street, 400006 Cluj-Napoca, - - 2014
The aim of our study was to assess the effect of the combined treatment of Metformin (Metf) and 5, 10, 15, 20-tetra-sulfophenyl-porphyrin (TSPP)-mediated photodynamic therapy (PDT) on an in vivo tumour model. Wistar male rats were divided in 6 groups: group 1, treated with TSPP; groups 2 and 4 treated ...
Kim Bong Jik BJ Department of Otolaryngology-Head & Neck Surgery, Dankook University College of Medicine, Cheonan, Korea. ; Department of Otorhinolaryngology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, - - 2014
The purpose of this study was to evaluate the therapeutic effect of three different types of sounds on tinnitus patients undergoing tinnitus retraining therapy (TRT). This is a single-institution retrospective study, performed in one tertiary otological referral center. Thirty-eight adults with subjective idiopathic tinnitus who were followed for at least ...
Rodger Marc M Thrombosis Program, Division of Hematology, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Clinical Epidemiology Program, Ottawa Hospital Research Institute, The Ottawa Hospital, Ottawa, Ontario, - - 2014
Patients who experience venous thromboembolism (VTE) are at important risk for recurrent VTE[1]. When it occurs, recurrent VTE may have serious consequences. Recurrent VTE is fatal in more than 1 in 10 patients if experienced in the first 3 months of therapy and after the initial 3 months of therapy, ...
Takazono Takahiro T Department of Internal Medicine, Nagasaki Municipal Hospital, Nagasaki, Japan; Department of Respiratory Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan. Electronic address: - - 2014
The novel biological agent recombinant human thrombomodulin (rhTM) has been used clinically in Japan to treat disseminated intravascular coagulation (DIC) since 2008. Previous studies have shown the efficacy of rhTM versus heparin therapy or non-rhTM therapy. We retrospectively evaluated and compared the efficacies of rhTM and gabexate mesilate (GM) in ...
Maessen-Visch M Birgitte MB Rijnstate Ziekenhuis, Arnhem, the Netherlands - - 2014
The revised guideline of 2013 is an update of the 2005 guideline "venous leg ulcer". In this special project four separate guidelines (venous leg ulcer, varicose veins, compression therapy and deep venous disorders) were revised and developed simultaneously. A meeting was held including representatives of any organisation involved in venous ...
van der Velden Sk S Department of Dermatology, Erasmus MC, Rotterdam, the Netherlands - - 2014
Compression therapy is still the cornerstone in the treatment of PTS. The therapy is primarily focused on the decrease of the AVP, enhancement of the microcirculation and reduction of the edema. In our practice, most patients are initially treated with short stretch bandage to reduce the edema. Medical Elastic Compression ...
Bouman Ac A Laboratory for Thrombosis and Hemostasis, Maastricht University Medical Centre, Maastricht, the Netherlands Department of Internal Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands - - 2014
After deep vein thrombosis (DVT) 20-50%, of patients develop post thrombotic syndrome (PTS). Up till now, there is no effective treatment for PTS and prevention is therefore of major importance. Compression therapy after DVT, with elastic compression stockings (ECS), is the only available preventive measure for PTS. However, the usefulness, ...
- - 2014
In the acute respiratory distress syndrome (ARDS), inflammation in the lungs and other organs can cause life-threatening organ failure. Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase (statins) can modulate inflammatory responses. Previous observational studies suggested that statins improved clinical outcomes in patients with sepsis. We hypothesized that rosuvastatin therapy would improve ...
Liu Ning N Department of Radiation Oncology, Shandong Cancer Hospital & Institute, Jinan, - - 2014
Self-expandable stents loaded with (125)I (iodine 125) seeds may combine the advantages of the immediate relief of esophageal dysphagia with stent placement and radiation therapy with brachytherapy. We compared the self-expanding irradiation stent with a conventional self-expandable covered stent in patients with malignant dysphagia due to recurrent esophageal cancer. The ...
Seibel Ira I Augenklinik, Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany. Electronic address: - - 2014
To evaluate the potential benefit and risk of proton beam therapy in the treatment of symptomatic retinal papillary capillary hemangioma. Retrospective interventional case series METHODS: This study included patients presenting with symptomatic exudative retinal papillary capillary hemangioma with or without association with von Hippel- Lindau (vHL) disease. All patients were ...
Beppu Takahiro T Department of Gastroenterology, Fukuoka University Chikushi Hospital, Fukuoka, - - 2014
The aim of this study was to endoscopically evaluate ileal mucosal healing during maintenance therapy with infliximab in order to investigate the clinical significance of endoscopic examination of ileal lesions in Crohn's disease patients. This study retrospectively analyzed 54 patients who mainly had active ulcers of the ileum on endoscopy ...
Raheja Jyoti J Department of Conservative Dentistry & Endodontics, Post Graduate Institute of Dental Sciences, Rohtak, Haryana, - - 2014
Background: Treatment of concomitant endodontic-periodontal lesions remains a challenge in clinical practice and requires effective endodontic and regenerative periodontal therapy. Among other factors cross seeding and recolonization of flora may affect the outcome of periodontal therapy. Intracanal medicaments have shown to exert antimicrobial activity on external root surface and local ...
Iorio-Siciliano Vincenzo V University of Naples "Federico II", Department of Dental and Maxillofacial Sciences, Naples, - - 2014
Background: To compare the clinical outcomes in the treatment of deep non-contained intrabony defects (i.e. with at least a 70% 1-wall component and a residual 2- to 3-wall component in the most apical part) with deproteinized bovine bone mineral (DBBM) combined with either enamel matrix protein derivative (EMD) or collagen ...
Kloppe Axel A Medizinische Klinik II, Kardiologie und Angiologie, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Ruhr-Universität-Bochum, Bochum, - - 2014
-Three trials recently demonstrated that a long detection window reduce ICD therapy in primary prevention (PP) patients. Advance III was the only trial enrolling both PP and secondary prevention (SP) patients. -Out of 1902 patients enrolled in the ADVANCEIII trial, 477 received a defibrillator for SP : 248 pts were ...
Sun Xinjuan X Department of Endocrinology, The 454(th) Hospital of Chinese PLA, Nanjing, - - 2014
This study aimed to systematically evaluate maggot debridement therapy (MDT) in the treatment of chronically infected wounds and ulcers. We performed a meta-analysis referring to the PRISMA statement (Preferred Reporting Items for Systematic Reviews and Meta-Analyses). We searched for published articles in the following databases: PubMed, Web of Science, Embase, ...
Silva-Boghossian Carina Maciel CM Department of Medical Microbiology, Institute of Microbiology Paulo de Goes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, - - 2014
The present study investigated the effect of non-surgical periodontal treatment (SRP) on the composition of the subgingival microbiota of chronic periodontitis (CP) in individuals with type 2 diabetes (DM2) with inadequate metabolic control and in systemically healthy (SH) individuals. Forty individuals (20 DM2 and 20 SH) with CP underwent full-mouth ...
Zhou You Lian YL Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong Province, - - 2014
This study aimed to evaluate the efficacy including the patients' response rates to infliximab (IFX) therapy, relapse rates after IFX-induced clinical remission, and safety of the therapy in Chinese patients with ulcerative colitis (UC) from a single center in Southern China and to identify the risk factors associated with disease ...
Deng Yongming Y Division of Nephrology, General Hospital of Tibet Military Command , Lhasa, Tibet , China - - 2014
Abstract Background: Calcific uremic arteriolopathy (CUA), previously called calciphylaxis, is a devastating complication of end-stage kidney disease (ESKD) with an annual incidence of 1-4% in dialysis patients and the mortality is as high as 80%. The rarity of the disease and the multifactorial nature of its causes have compromised good ...
Segal R L RL Brady Urological Institute, Johns Hopkins Hospital, Baltimore, MD, - - 2014
The objective of this study was to evaluate the modern utilization of penile prosthesis surgery based on data derived from national claim databases and contrast to an analysis of patients similarly treated at an academic center during a contemporaneous period. A retrospective claim analysis utilizing a national database (MarketScan, Thomson ...
Dosluoglu Hasan H HH Department of Anesthesiology, SUNY-Buffalo, Buffalo, NY, USA Department of Surgery, SUNY-Buffalo, Buffalo, NY, - - 2014
The aim of the study was to determine statin drug association with patency, limb salvage rates and survival after revascularization in patients with chronic limb ischemia. We retrospectively reviewed all patients who underwent revascularization for intermittent claudication or critical limb ischemia between 05/2001 and 12/2009. Patients were grouped based on ...
Wang Youhua Y Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, - - 2014
Several studies have reported that the application of ecabet sodium during the eradication of Helicobacter pylori can improve the eradication rate and reduce therapy-associated side effects. However, the efficacy and safety of this therapy are controversial. To determine whether ecabet sodium improves the eradication rate of H. pylori and examine treatment ...
Yildirim-Poyraz Nilufer N Department of Nuclear Medicine, Ankara Ataturk Research and Training Hospital, Bilkent No:2, Ankara, Turkey, - - 2014
The target of radioiodine ablation therapy (RIAT) after complete tumor removal is the nontumoral remnant tissue. We aimed to evaluate sodium iodide symporter (NIS) expression in nontumoral thyroid tissue in differentiated thyroid cancer (DTC) patients who have complete but delayed structural response (DSR) to RIAT after surgery. Preoperative thyroid characteristics ...
Kaune Kjell M KM Department of Dermatology, Venereology and Allergology, University Medical Center Göttingen, Germany; Dermatology and Allergology, Klinikum Bremen-Mitte, Bremen, - - 2014
Infantile hemangiomas (IH) can cause severe complications such as obstruction, ulceration or heart failure. Therefore, in certain difficult-to-treat areas, or when there is no sign of involution, early and effective therapy is required. In rare instances, systemic treatments, like the beta-blocker propranolol and oral corticosteroids, can cause serious side effects. ...
Ohrndorf S S Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, - - 2014
The objectives of this study are to evaluate a new semi-quantitative (0-5) musculoskeletal ultrasound (US) erosion score in patients with rheumatoid arthritis (RA) and to prove its usefulness in the detection of disease activity and success of therapy. Thirty-eight patients with RA (mean disease duration 10.1 ± 11.9 years) were enrolled. Start or ...
Kirchner Carmen C Department of General, Visceral and Transplant Surgery, University Hospital Essen, Essen, - - 2014
Allogeneic blood products transfusion during liver transplantation (LT) can be associated with increased morbidity and mortality. Data on thromboelastometry (ROTEM)-guided coagulation management with coagulation factor concentrates (CFCs)-fibrinogen concentrate and/or prothrombin complex concentrate (PCC)-are sparse. We aimed to retrospectively evaluate the safety events observed with this approach in our clinic. LT ...
Gulati Sheffali S Division of Pediatric Neurology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India. Electronic address: - - 2014
Neurocysticercosis, parasitic infestation of the central nervous system by the Taenia solium larvae, is a major public health problem, primarily in the developing countries. Seizures are the primary clinical manifestation which could be acute (secondary to active lesions) or remote symptomatic (due to calcified lesions). Cysticidal therapy is the standard ...
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