Search Results
Results 251 - 300 of 4163
< 1 2 3 4 5 6 7 8 9 10 11 >
Ochiai Shunsuke S Department of Orthopaedic Surgery, Teikyo University Chiba Medical Center, - - 2014
[Purpose] Superficial heat treatment is one of the most widely used physical therapies for osteoarthritis (OA). We clinically evaluated the effects of local heat treatment and exercise therapy for knee OA, and evaluated the articular cartilage using magnetic resonance imaging (MRI) T2 mapping. [Subjects and Methods] Eighteen females aged 50-69 ...
Malha Line P LP Department of Internal Medicine, New York University Medical Center, New York, - - 2014
To study the incidence of hypoglycemia, glycemic control and body weight changes in patients with type 2 diabetes treated with vildagliptin and metformin versus another group treated with sulphonylureas and metformin during and after the period of fasting in Ramadan. This is a randomized open-label clinical trial that recruited 69 ...
Jancoriene Ligita L Department of Infectious, Chest Diseases, Dermatovenerology and Alergology, Faculty of Medicine, Vilnius University, Vilnius, - - 2014
Patients with Hepatitis C are commonly treated with combination of Pegylated Interferon alfa-2a and Ribavirin. Less than 1% of patients receiving this treatment experience very uncommon ophthalmological side effects such as optic neuropathy and vision disorder, which are usually subclinical, mild and reversible, not requiring the withdrawal of the treatment. ...
Shamsi Meymandi Simin S Department of Dermatology, Kerman University of Medical Sciences, Kerman, IR - - 2014
Results of various studies suggest that the hypertrophic and keloid scars are highly prevalent in the general population and are irritating both physically and mentally. Considering the variety of existing therapies, intense pulsed light (IPL) method along with corticosteroid injection was evaluated in treating these scars. 86 subjects were included ...
Arslan Erhan E Department of Neurosurgery, School of Medicine, Giresun University, Nizamiye Mah. Mumcular Sok. No:1/1, 28000, Merkez/Giresun, Turkey, - - 2014
The aim of this study was to demonstrate regeneration of intervertebral discs undergoing laser therapy with sagittal relaxation time (T2) mapping after a long-term follow-up. Fourteen patients (9 men, 5 women; age range 20-57 years; mean age 36.5 years) treated with percutaneous 908-nm wave-length diode laser nucleoplasty for lumbar disc prolapsus at ...
Sullivan Renee M RM University of Missouri, Columbia, MO 65212, - - 2014
Implantable cardioverter-defibrillators (ICDs) treat ventricular tachycardia or fibrillation but may also deliver unnecessary shocks. We sought to determine if the frequency of ICD-detected non-sustained or diverted (NSD) episodes increases before appropriate or inappropriate ICD shocks.METHODS AND RESULTS: We evaluated NSD episodes in the INTRINSIC RV Trial and their relationship to ...
Rossi Valentina A VA University Hospital of Zurich, - - 2014
There are limited data on the evolution of obstructive sleep apnoea (OSA) during continuous positive airway pressure (CPAP) therapy and whether this treatment is required every night.125 OSA patients with an original oxygen desaturation index (ODI) >10 events per hour, established on CPAP, were asked to withdraw CPAP for four ...
Green Anna I AI Department of Endocrinology, Queen Elizabeth Hospital, University Hospital Birmingham NHS Foundation Trust, Edgbaston, Birmingham, - - 2014
Macroprolactinomas are pituitary tumours that can be managed with dopamine agonists (DA), surgery and radiotherapy. We aimed to assess the outcomes of these treatment modalities. Retrospective case-note study of patients managed in a single tertiary referral centre. One hundred patients (68 male) diagnosed with macroprolactinoma between 1971-2009. We assessed the ...
Alcocer Francisco F Section of Vascular Surgery and Endovascular Therapy, University of Alabama at Birmingham. Electronic address: - - 2014
Despite the established guidelines, there is not a clear consensus about how to manage antiplatelet therapy after carotid surgery. It is a common practice in vascular surgery to use the combination of aspirin and clopidogrel in the treatment of such patients. In this work, we analyzed the impact on long-term ...
Peters Charlotte P CP Department of Gastroenterology and Hepatology, Academic Medical Center, The - - 2014
Adalimumab is an effective therapy for induction and maintenance of Crohn's disease. However, results in clinical trials don't necessarily reflect daily clinical practice. Therefore, we assessed real-life long-term clinical response to adalimumab in a large population-based cohort and identified clinical parameters affecting response METHODS: All consecutive patients in North-Holland that ...
Wang Ching-Jen CJ Center of Shockwave Medicine and Tissue Engineering, Department of Orthopedic Surgery, Chang Gung Memorial Hospital/Kaohsiung Medical Center, Chang Gung University College of Medicine, - - 2014
Shockwave was shown to enhance the healing of anterior cruciate ligament (ACL) reconstruction in rabbits. This study evaluated the effect of extracorporeal shockwave therapy (ESWT) on ACL reconstruction in human subjects. We hypothesized that ESWT may improve human ACL reconstruction. Fifty-three patients were randomized into two groups with 26 patients ...
Martin Jeremiah J Department of Surgery, University of Kentucky, Lexington, Kentucky, - - 2014
Pneumonectomy for nonmalignant disease is unusual. We wondered about the incidence, predisposing risks, and outcomes of this entity. We interrogated the Society of Thoracic Surgeons General Thoracic Surgery Database to compare patients undergoing pneumonectomy for benign or malignant indications between 2006 and 2010. 309 of 3081 (10%) patients underwent pneumonectomy ...
Aboud S K - - 2014
Nasal polyposis (NP) has a great impact on quality of life (QOL) and its management involves a combination of medical therapy and surgery. To the authors? knowledge, no publication has extensively examined NP after optimal medical treatment based on subjective evaluations. The aim of this prospective study was designed to ...
Lippe Christina C Penn State University College of Medicine, Hershey, - - 2014
Objectives: This study explores bleeding risk of warfarin patients undergoing radial catheterization. Background: Traditionally warfarin has been held prior to catheterization due to bleeding risk; however, this practice is being reconsidered with radial access. This study examined if radial patients receiving warfarin have similar hemostasis times to those not taking ...
Gali Wagner L WL Clinical Arrhythmia and Pacemaker Unit, Instituto de Cardiologia do Distrito Federal (IC-DF), Fundação Universitária de Cardiologia (FUC), AOS 02 Bloco B apto 604, Brasília, 70660-022 DF, - - 2014
Evidence is inconclusive concerning the benefit of implantable cardioverter-defibrillators (ICDs) for secondary prevention of mortality in patients with Chagas' heart disease (ChHD). The aim of this study was to compare the outcomes of ChHD patients with life-threatening ventricular arrhythmias (VAs), who were treated either with ICD implantation plus amiodarone or ...
Rubboli Andrea A Division of Cardiology, Laboratory of Interventional Cardiology, Ospedale Maggiore, Bologna, - - 2014
Most evidence regarding the efficacy and safety of the antithrombotic regimens for patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention with stent (PCI-S) derives from small, single-center, retrospective datasets. To obtain further data on this issue, we carried out the prospective, multicenter, observational Management of patients with Atrial Fibrillation ...
Xia Juan J Departments of *Anesthesiology †Neurosurgery, Huashan Hospital, Fudan University, Shanghai, P. R. - - 2014
Compared with goal-directed crystalloid therapy, goal-directed colloid therapy during high-risk surgery may improve postoperative outcome. Whether intraoperative fluid therapy based on goal-directed protocol with different types of fluid has distinctive effects on brain relaxation and cerebral metabolism during craniotomy remains unclear. Forty patients with supratentorial brain tumors undergoing craniotomy were ...
Alemayehu Hanna H Department of Surgery, Center for Prospective Clinical Trials, Children's Mercy Hospital, 2401 Gillham Road, Kansas City, MO, 64108, - - 2014
Ceftriaxone has been associated with development of pseudolithiasis. In our institution, it is used for treatment of perforated appendicitis in children. This study evaluated the occurrence of ceftriaxone-related pseudolithiasis in this population. After obtaining IRB approval, we performed a retrospective chart review over 51 months. We included patients undergoing laparoscopic appendectomy ...
Chatu Sukhdev S Department of Gastroenterology, St George's University Hospital, London, - - 2014
OBJECTIVES:The efficacy of thiopurines (TPs) in altering the risk of surgery in Crohn's disease (CD) remains controversial. We evaluated the impact of TP therapy, optimal timing, and duration of TP therapy on first intestinal resection rates using a population-based cohort.METHODS:We constructed a population-based cohort of incident cases of CD between ...
Lødrup Anders A Department of Medicine, Køge University Hospital, University of Copenhagen, Køge, - - 2014
Antireflux surgery (ARS) has been suggested as an alternative to lifelong use of proton pump inhibitors (PPI) in reflux disease. Data from clinical trials on PPI use after ARS have been conflicting. We investigated PPI use after ARS in the general Danish population using nationwide healthcare registries. A nationwide retrospective ...
Salimi Alireza A a Department of Anesthesiology, Loghman Hakim Hospital , Shahid Beheshti University of Medical Sciences , Tehran , - - 2014
Background: Ultra-Rapid Opioid Detoxification (UROD) and subsequently induction of Naltrexone maintenance therapy can be regarded as safe and effective detoxification method in patients with opiate addiction. Long term efficacy, relapse time and rate of this method is not clear. Aim: to assess UROD efficacy and estimate the relapse rate in ...
Lip Gregory Y H GY University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, United Kingdom. Electronic address: - - 2014
Current guidelines strongly recommend that oral anticoagulation can be offered to patients with atrial fibrillation and ≥1 stroke risk factors. Also, the guidelines recommend that oral anticoagulation should still be used in the presence of stroke risk factors irrespective of rate or rhythm control METHODS AND RESULTS: In an analysis ...
Baert Filip F Dept of Gastroenterology University Hospitals Leuven, Belgium. Electronic address: - - 2014
Few agents are available for treatment of inflammatory bowel diseases (IBD), and patients frequently become unresponsive to biologics. We investigated the feasibility of re-initiating infliximab therapy for patients who previously received only episodic therapy with, lost response to, or had infusion reactions to infliximab. We also aimed to identify factors ...
Chen Xiong X Department of Otolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, - - 2014
Continuous positive airway pressure (CPAP) is an effective treatment for obstructive sleep apnea hypopnea syndrome (OSAHS), but previous studies assessing the effect of CPAP on homocysteine (HCY) in patients with OSAHS yielded conflicting results. In this study, we conducted a meta-analysis to determine whether CPAP therapy could reduce plasma HCY ...
Monterubbianesi Rita R Gastroenterology Unit, S. Camillo-Forlanini Hospital, Rome, Italy. Electronic address: - - 2014
Infliximab is effective as rescue therapy in severe corticosteroid-refractory ulcerative colitis. The optimal dose regimen and the long term benefits are not well defined. The aim of the present study was to evaluate short- and long-term colectomy rate in a cohort of patients with severe corticosteroid-refractory ulcerative colitis who received ...
Nagashima Makoto M Department of Surgery, Toho University Sakura Medical Center, 564-1 Shimoshizu, Sakura, 285-8741, Japan, - - 2014
The oxaliplatin-based regimen FOLFOX is widely used to treat patients with advanced colorectal cancer (CRC). However, dose-limiting toxicity after continuous oxaliplatin administration can lead to peripheral neuropathy. Several agents, including opioids, that have been employed to treat oxaliplatin-induced peripheral neuropathy (OIPN) have been examined in clinical settings regarding their protective ...
Pinfildi Carlos E CE 1 Department of Human Movement Science, University Federal of São Paulo - UNIFESP - Campus Baixada Santista , Santos, SP, Brazil - - 2014
Abstract Objective: The aim of this study was to quantify mast cells at different time intervals after partial Achilles tendon rupture in rats treated with low-level laser therapy (LLLT). Background data: There is a high incidence of lesions and ruptures in the Achilles tendon that can take weeks and even ...
Imaz Arkaitz A HIV Unit, Department of Infectious Diseases, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Spain. - - 2014
There are no clinical trials in which the main objective is to compare the efficacy of efavirenz versus ritonavir-boosted protease inhibitor (PI/r)-based initial antiretroviral therapy (ART) in patients with high plasma HIV-1 RNA levels. This study aims to compare these regimens in this patient population in the setting of routine ...
Javed Fawad F Engineer Abdullah Bugshan Research Chair for Growth Factors and Bone Regeneration, 3D Imaging and Biomechanical Lab., College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia, - - 2014
The aim of the present short-term longitudinal randomized case-control study was to assess the effect of nonsurgical periodontal therapy (NSPT) (with and without oral doxycycline delivery) on glycemic status and clinical periodontal parameters in patients with prediabetes. Sixty-six patients with prediabetes and periodontal disease were included. Characteristics of the study ...
Hesse Stefan S 1Medical Park Berlin, Department of Neurological Rehabilitation, Charité University, Berlin, - - 2014
Objective:To evaluate the effectiveness and efficiency of robot-assisted arm group therapy (RAGT) versus individual arm therapy (IAT) to restore motor function in the moderately to severely affected patient after stroke.Design:Single blind randomized controlled trial.Setting:Two in-patient neurological rehabilitation centers.Participants:Fifty first time subacute patients with stroke and a non-functional hand.Intervention:The patients practiced ...
Prieto-Alhambra D D Oxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, - - 2014
Osteolysis and subsequent prosthesis loosening is the most common cause for revision following total knee arthroplasty (TKA) or total hip arthroplasty (THA). Hormone replacement therapy (HRT) could reduce osteolysis through its antiresorptive effects. We studied whether HRT use is associated with reduced revision rates in a community-based cohort of women ...
Rees Jonathan D JD Department of Rheumatology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, - - 2014
The British military has a cohort of patients with ankylosing spondylitis (AS) characterised by young age and short disease duration. Many of the most severely affected AS patients have been treated since 2005 at Headley Court with anti-tumour necrosis factor (anti-TNF) therapy in accordance with National Institute of Health and ...
Kouvelos George N GN 1Department of Surgery-Vascular Surgery Unit, School of Medicine, University of Ioannina, Ioannina, - - 2014
We compared the effects of lipid lowering with rosuvastatin (RSV) monotherapy versus intensified treatment by combining RSV with ezetimibe (EZT) on kidney function in patients undergoing vascular surgery. Patients were randomly assigned to either 10 mg/d RSV (n = 136) or RSV 10 mg/d plus EZT 10 mg/d (RSV/EZT, n ...
Wang Xiaohong X Department of Infectious Diseases, Southwest Hospital, The Third Military Medical University, Chongqing, China. Electronic address: - - 2014
Entecavir (ETV) plus adefovir (ADV) combination therapy may be a promising option for chronic hepatitis B (CHB) patients who have failed on prior nucleos(t)ide analog (NA) treatment. However, the long-term efficacy and safety of this combination are not well-defined. In a single-center, retrospective study, 104 patients (mean age 31.7 years; ...
Ouyang Jing J Southwest Hospital, Third Military Medical University, Chongqing, 400038, - - 2014
The objective of this study was to evaluate the efficacy and safety of a traditional Chinese medicine, Fufang Xuelian Burn Ointment (FXBO), to treat superficial and deep second-degree burn wounds. A four-center, randomized, controlled, and prospective study was conducted. Overall, 240 patients with either superficial or deep second-degree burn wounds ...
Nagahara Akihito A Department of Gastroenterology, Juntendo University School of Medicine , Tokyo , - - 2014
Abstract Aim. To assess the efficacy of continuous therapy (cont) and on-demand therapy (on-demand) as maintenance therapy for gastroesophageal reflux disease (GERD). Methods. Patients with upper GI endoscopy (EGD)-proven GERD who completed 8 weeks of initial therapy were randomized to cont (omeprazole 20 mg od) or on-demand (omeprazole 20 mg ...
Sobolewska Bianka B *Center for Ophthalmology, Eberhard-Karls University, Tuebingen, Germany; and †Department of Dermatology, Eberhard-Karls University, Tuebingen, - - 2014
The aim of this study was to determine the efficacy of once-daily systemic treatment of ocular rosacea with a slow-release form of 40 mg of doxycycline. Fifteen patients with ocular rosacea were enrolled between February 2010 and October 2012 in a retrospective observational case series. Patient complaints and clinical findings ...
Kanizaj Tajana Filipec TF Tajana Filipec Kanizaj, Department of gastroenterology, University hospital Merkur, School of Medicine, University of Zagreb, Zagreb 10000, - - 2014
The rising prevalence of antibiotic resistance has created a need to reassess the established Helicobacter pylori (H. pylori) eradication protocols, and to develop new ones. Various bacterial and host factors are evaluated, and their contribution to eradication failure is estimated. For a long time being considered the cornerstone eradication scheme, ...
Broeckx Sarah S Global Stem cell Technology, Meldert-Lummen, - - 2014
Degenerative joint disease (DJD) is a major cause of reduced athletic function and retirement in equine performers. For this reason, regenerative therapies for DJD have gained increasing interest. Platelet-rich plasma (PRP) and mesenchymal stem cells (MSCs) were isolated from a 6-year-old donor horse. MSCs were either used in their native ...
Kazamia Kalliopi K Department of Women's and Children's Health, Uppsala University, Uppsala, - - 2014
To study real-life experiences of drug treatment discontinuations and safety in a well-defined cohort of patients with juvenile idiopathic arthritis (JIA), over an eleven-year period in Uppsala County, Sweden. Clinical charts of all incident and prevalent cases of juvenile arthritis were reviewed prospectively by an experienced paediatric rheumatologist. Each patient ...
Santantonio Teresa T Infectious Diseases, University of Foggia, - - 2014
Background and aims: Therapy of acute hepatitis C (AHC) has not yet been standardized and several issues are still unresolved. This open randomized multicentre trial aimed to assess efficacy and safety of a 24-week-course of pegylated IFN (Peg-IFN) alpha-2b versus a 12 week-course of Peg-IFN alpha-2b alone or with ribavirin ...
Nobile Stefano S aInflammatory Bowel Disease Unit, Policlinico S. Orsola-Malpighi, University of Bologna, Bologna bMaternal and Child Department, Ospedali Riuniti di Ancona, Ancona, - - 2014
The anti-tumor necrosis factor (TNF) agents infliximab (IFX) and adalimumab (ADA) have been recently introduced to treat severe inflammatory bowel disease (IBD) that is unresponsive to other drugs. Several studies have confirmed the safety and efficacy of these agents for adult IBD patients, whereas there is less data on pediatric ...
Hukkinen Maria M Pediatric Liver and Gut Research Group, Section of Pediatric Surgery, Children's Hospital, University of Helsinki, Finland. Electronic address: - - 2014
Treatment of complex perianal fistulas associated with Crohn's disease is challenging. In adults, seton drainage combined with infliximab therapy has proven to be more effective than either one alone. Results following such treatment among pediatric patients have not been reported previously. The aim of this study was to describe outcomes ...
De Rango P P Unit of Vascular and Endovascular Surgery, Hospital S. Maria Misericordia, Perugia, Italy. Electronic address: - - 2014
Current data supporting the effect of anticoagulation drug use on aneurysm sealing and the durability of endovascular abdominal aneurysm repair (EVAR) are conflicting. This study assessed the safety of chronic anticoagulation therapy after EVAR. Records of 1409 consecutive patients having elective EVAR during 1997-2011 who were prospectively followed were reviewed. ...
Baysal Ayse A Anesthesiology and Reanimation Clinic, Kartal Kosuyolu High Speciality Training and Research Hospital, Istanbul, Turkey. Electronic address: - - 2014
The effect of levosimendan on renal function in patients with low ejection fraction undergoing mitral valve surgery was investigated. A prospective, double-blinded, randomized clinical trial. Tertiary teaching and research hospital. Of a total of 147 patients, 128 patients completed the study. In the levosimendan group (n = 64), levosimendan was ...
Oto Yuji Y Department of Pediatrics, Dokkyo Medical University, Koshigaya Hospital, Saitama, - - 2014
Long-term treatment with growth hormone (GH) in patients with Prader-Willi syndrome (PWS) improves not only height velocity, height standard deviation score, and final height, but also the degree of obesity and body composition abnormalities. Anecdotally, PWS patients tend to suffer from severe obesity and its complications after cessation of GH ...
Takarada Ken K Tachikawa General Hospital, Cardiovascular Center, Nagaoka, Japan; Tokyo Medical University, Department of Cardiology, Tokyo, - - 2014
Anticoagulation therapy is essential in atrial fibrillation (AF), and in Japan, less intense control is popular. To assess the efficacy and safety with a special reference to low intensity warfarin therapy. In 488 out of 508 patients with non-valvular AF, prothrombin time-international normalized ratio (PT-INR) was kept at 1.6-2.59, and ...
Kang Seong Hee SH Department of Internal Medicine, Korea University Medical College, Seoul, Republic of - - 2014
Data regarding the management of adefovir (ADV) resistance are still limited. The aim of this study is to investigate treatment outcomes of rescue therapy in ADV-resistant chronic hepatitis B (CHB) patients. CHB patients who began rescue therapy due to documented genotypic resistance mutations to ADV between October 2006 and July ...
Kowdley Kris V KV From the Digestive Disease Institute, Virginia Mason Medical Center, Seattle (K.V.K.); Texas Liver Institute, University of Texas Health Science Center, San Antonio (E.L., F.P.); AbbVie, North Chicago (D.E.C., W.X., T.P.-M., G.L., L.L., A.K., T.P., B.B.); University of Florida College of Medicine, Gainesville (D.R.N.); J.W. Goethe University, Frankfurt, Germany (S.Z.); University of Colorado Denver, Aurora (G.T.E.); Indiana University, Indianapolis (P.K.); Queen Mary, University of London, Barts Health, London (G.R.F.); and Johns Hopkins University, Baltimore - - 2014
An interferon-free combination of the protease inhibitor ABT-450 with ritonavir (ABT-450/r), the nonnucleoside polymerase inhibitor ABT-333, and ribavirin showed efficacy against the hepatitis C virus (HCV) in a pilot study involving patients with HCV genotype 1 infection. The addition of another potent agent, the NS5A inhibitor ABT-267, may improve efficacy, ...
Bucheit John J John Bucheit, Pharm.D., is Pharmacy Practice Resident, Pharmacy Department; Rebeccah Collins, Pharm.D., is Residency Director, Antimicrobial Stewardship; and Prajwol Joshi, M.D., is Infectious Disease Physician, Infectious Disease, Memorial Regional Medical Center, Mechanicsville, - - 2014
A case of a patient who received ceftaroline fosamil as salvage therapy for a methicillin-resistant Staphylococcus aureus (MRSA) epidural abscess is reported. A 48-year-old white woman arrived at the emergency department (ED) with an altered mental status. She had been to the ED two days prior with complaints of sudden-onset ...
< 1 2 3 4 5 6 7 8 9 10 11 >