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Results 201 - 250 of 4756
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Fernandes Ana Paula AP Department of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, São Paulo, - - 2014
This study aimed to compare the clinical and radiographic effectiveness of Low Level Laser Therapy in vital pulp of human primary teeth. Sixty mandibular primary molars of children aged between 5-9 years were assigned into four groups: Diluted Formocresol (FC), Calcium Hydroxide (CH), Low Level Laser Therapy (LLLT) and Calcium Hydroxide ...
Togsverd-Bo K K Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, - - 2014
Topical photodynamic therapy (PDT) for actinic keratoses (AK) is hampered by pain during illumination and inferior efficacy in organ-transplant recipients (OTR). We assessed ablative fractional laser (AFL)-assisted daylight photodynamic therapy (PDT) (AFL-dPDT) compared to daylight PDT (dPDT), conventional PDT (cPDT) and AFL alone (AFL) in field treatment of AK in ...
Gupta Gaurav G 1 Department of Medicine, Virginia Commonwealth University, Richmond, VA. 2 Department of Medicine, University of Cincinnati, Cincinnati, OH. 3 Department of Pathology, Johns Hopkins University, Baltimore, MD. 4 Department of Medicine, Johns Hopkins University, Baltimore, MD. 5 Department of Pharmacy, Johns Hopkins Hospital, Baltimore, MD. 6 Department of Surgery, Johns Hopkins University, Baltimore, MD. 7 Address correspondence to: Nada Alachkar, MD, Johns Hopkins University School of Medicine, 600 Wolfe Street, Brady 502, Baltimore, MD - - 2014
Although several strategies for treating early antibody-mediated rejection (AMR) in kidney transplants have been investigated, evidence on treatment of late AMR manifesting after 6 months is sparse. In this single-center series, we present data on 23 consecutive patients treated for late AMR. Late AMR was diagnosed using Banff 2007 criteria ...
Khandelwal P P Bone Marrow Transplant and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH. Electronic address: - - 2014
Therapy of refractory autoimmunity remains challenging. In this study, we evaluated the therapeutic effect of bortezomib, a proteasome inhibitor, by targeting plasma cells in seven patients, median age 9.9 years. Four doses of bortezomib were administered at a dose of 1 3.mg/m2 intravenously (n=6) or subcutaneously (n=1) every seventy-two hours. ...
Ion Daniela D Oral Medicine Department, Guy's and St. Thomas' NHS Foundation Trust, London, - - 2014
Acute graft-versus-host-disease (aGVHD) is a major complication of allogeneic hematopoietic stem cell transplantation (HSCT). The purpose of this study was to characterize the oral features associated with aGVHD. Patients who underwent HSCT between 1995 and 2010 and developed prominent oral aGVHD. Data was collected from patient medical records and analyzed ...
Yang Xi X *Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China; †Special Department of Hemangioma, Hospital of PLA General Political Department, Beijing, - - 2014
Lymphangioma circumscriptum (LC) is a type of microcystic lymphatic malformation involving the skin and mucosa that presents as translucent vesicles of varying size with a pink, red, or black hue. Lymphangioma circumscriptum causes not only cosmetic problems but also refractory rupture, infection, lymphorrhea, and bleeding. Various invasive methods, such as ...
Honda Shigeru S Department of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine, Kobe, - - 2014
Background: To compare the outcomes of photodynamic therapy (PDT) between two different angiographic subtypes of polypoidal choroidal vasculopathy (PCV). Methods: Ninety-three consecutive cases of PCV were classified into two phenotypes (42 type 1 and 51 type 2) according to the presence or absence of feeding vessels found on indocyanine green ...
Walsh Michael M Departments of Medicine and Clinical Epidemiology and Biostatistics, Population Health Research Institute, McMaster University and Population Health Research Institute, Hamilton, Ontario, Canada; - - 2014
Treatment with azathioprine within 3 months of remission induction with cyclophosphamide is a common treatment strategy for patients with ANCA-associated vasculitis. This study comprised patients undergoing long-term follow-up who were randomly allocated to azathioprine after 3-6 months or after 12 months of cyclophosphamide treatment.DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Patients from ...
Haider Ahmad A Private Urology Practice, Bremerhaven, - - 2014
Although there is no evidence that testosterone (T) therapy increases risk of prostate cancer (PCa), there is a paucity of long-term data. To determine whether incidence of PCa is increased in hypogonadal men receiving long-term T therapy. In three parallel, prospective, ongoing, cumulative registry studies, 1,023 hypogonadal men received T ...
Bhamra-Ariza Paul P Cardiology Dept, St Vincent's Hospital, Victoria St, Darlinghurst, NSW 2010, - - 2014
Mitral regurgitation is the most common valve abnormality worldwide and its prevalence is expected to increase in the future due to aging of the population. Percutaneous mitral valve repair therapies may offer an opportunity to treat severe MR in the elderly or other high-risk groups who would otherwise be ineligible ...
May Teresa L TL Division of Pulmonary and Critical Care Medicine, Maine Medical Center, 22 Bramhall St, Portland, ME, 04102, USA, - - 2014
Sedation and analgesia regimens during targeted temperature management (TTM), after cardiac arrest varies widely, are poorly described in the literature and may have a negative impact on outcome. Since implementing TTM in 2005, we have used moderate-dose sedation and describe our experience with this approach. In this retrospective review, we ...
Almond L M LM Department of Upper Gastrointestinal Surgery, Gloucestershire Royal Hospital, - - 2014
The optimal management of patients with Barrett's-associated low-grade dysplasia (LGD) is unclear. The objective of this study was to identify systematically all reports of endoscopic treatment of LGD, and to assess outcomes in terms of disease progression, eradication of dysplasia and intestinal metaplasia, and complication rates. A systematic review of ...
Raman Renukanth Patabi - - 2014
40 subjects with type 2 diabetes and moderate to severe CP were randomly distributed to groups receiving either NSPT or OHI. Periodontal parameters, glycosylated haemoglobin (HbA1c) and high-sensitivity C-reactive protein (hs-CRP) were evaluated at baseline, 2- and 3-months intervals. 40 subjects with type 2 diabetes and moderate to severe CP ...
Zhang Bin B Laser Plastic and Aesthetic Center, Liuhuaqiao Hospital, Guangzhou, - - 2014
Several studies suggest that vascular-acting photodynamic therapy (PDT) might be an alternative approach for treating port wine stain birthmarks (PWS) but the usefulness of PDT for pediatric patients has not been fully investigated. Study design: Medical records of pediatric patients (3 - 10 years old) with red and purple facial ...
Driul L L Clinic of Obstetrics and Gynecology, AOU 'SM della Misericordia' of Udine , Udine , - - 2014
The objective of this study was to compare the safety and efficacy of atosiban and ritodrine in the treatment of threatened preterm labour (TPL) and to analyse the predictive factors of preterm delivery. We retrospectively sampled data on 380 women hospitalised for TPL (24-35 weeks' gestation), in our clinic between ...
Coutin Julia V JV Department of Small Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Blacksburg, - - 2014
To compare cefazolin concentrations in biopsied tissue samples collected from surgically created wounds treated with negative pressure wound therapy to those collected from surgically created wounds treated with nonadherent dressings. Prospective, controlled, experimental study. Adult female spayed Beagles (n = 12). Full thickness cutaneous wounds were created on each antebrachium (n = 24). Immediately ...
Nishikawa Hiroki H Department of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Osaka 543-0027, - - 2014
We examined whether supplementation of branched-chain amino acid (BCAA) granules in an early stage of underlying liver disease (pretreatment serum albumin levels ≥3.6 g/dl) can improve overall survival (OS) after therapy for hepatocellular carcinoma (HCC) using propensity score matching analysis. We compared OS between patients treated with BCAA granules and control ...
Rustagi Tarun T Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, - - 2014
Chronic radiation proctopathy (CRP) is a common sequela occurring even many years after pelvic radiation. Current ablative therapies for bleeding ectatic vessels have the potential for deep tissue injury leading to ulcerations, perforation, and fistulas. Radiofrequency ablation (RFA) therapy avoids deep tissue injury and is a promising treatment for CRP. ...
Malyar Nasser M NM Division of Vascular Medicine, Department of Cardiovascular Medicine, University of Muenster, Muenster, Germany. Electronic address: - - 2014
The purpose of this study was to evaluate the effect of autologous bone marrow mononuclear cells (BM-MNCs) on symptoms and perfusion indices in severely symptomatic patients with peripheral arterial disease (PAD) without further option for endovascular or surgical revascularization. Only patients with severe symptomatic PAD (Fontaine class IIb-IV, Rutherford category ...
Pariente B B Service d'hépato-gastroentérologie, Hôpital Saint-Louis, Université Paris VII, Paris, - - 2014
Therapeutic objectives are currently evolving in inflammatory bowel diseases (IBD) from control of symptoms towards improvement of long-term disease outcomes. In patients achieving remission, safety concerns - infections or neoplasia - and economic issues are prompting de-escalation strategies. To give a complete overview of studies on de-escalating therapy in IBD. ...
Kapellas Kostas K From the Australian Research Centre for Population Oral Health, School of Dentistry, University of Adelaide, Adelaide, South Australia, Australia (K.K., L.M.J., L.G.D.); Preventable Chronic Disease Division (K.K., L.J.M.-B.) and Global Health Division (N.M.A., H.W.), Menzies School of Health Research, and School of Psychology and Clinical Science (H.W.), Charles Darwin University, Darwin, Northern Territory, Australia; Division of Medicine, Royal Darwin Hospital, Darwin, Northern Territory, Australia (L.J.M.-B., N.M.A.); Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia, Australia (K.O.); Aboriginal Research Unit, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia (A.B.); NHMRC Clinical Trials Centre (D.R.S.), Sydney Medical School (T.Y.C.), Department of Medicine (D.S.C.), and Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders (M.R.S.), University of Sydney, Sydney, New South Wales, Australia; Department of Cardiology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia (D.R.S.); and Department of Dental Ecology, University of North Carolina at Chapel Hill (G.D.S.). - - 2014
Observational studies and nonrandomized trials support an association between periodontal disease and atherosclerotic vascular disease. Both diseases occur frequently in Aboriginal Australians. We hypothesized that nonsurgical periodontal therapy would improve measures of arterial function and structure that are subclinical indicators of atherosclerotic vascular disease. This parallel-group, randomized, open label clinical ...
Stephan Christoph C Medical Department no. 2, Infectious Diseases Unit, University Hospital Frankfurt, Frankfurt, - - 2014
The rapid early-phase decay of plasma HIV-1 RNA during integrase inhibitor-based therapy is not fully understood. The accumulation of biologically active episomal HIV-1 cDNAs, following aborted integration, could contribute to antiviral potency in vivo. This prospective, controlled clinical observation study explored raltegravir's impact on the dynamics of HIV-1 RNA in ...
Thomson Rebekah R Cardiothoracic Intensive Care Unit, St Georges NHS Hospital Trust, London, United Kingdom. Electronic address: - - 2014
The purpose of this study was to assess the effect of goal-directed therapy (GDT), after cardiac surgery, on the incidence of acute kidney injury (AKI). This is a prospective observational study designed to achieve and maintain maximum stroke volume for 8 hours, in patients after cardiac surgery. This is a ...
Okada Takeshi T Department of Surgical Neurology, Research Institute for Brain and Blood Vessels Akita, Akita, Japan. Electronic address: - - 2014
It is controversial whether taking antiplatelet agents (APs) or anticoagulant agents (ACs) could influence clinical outcome after intracerebral hemorrhage (ICH). We retrospectively investigated 557 ICH patients between September 2008 and August 2013. We reviewed patients' characteristics, hematoma volume, deterioration (hematoma expansion, surgical hematoma evacuation, or death), and clinical outcome in ...
Hollinger Laura E LE Department of Surgery, The Methodist Hospital and Research Institute, Houston, TX; The Department of Pediatric Surgery, The University of Texas School of Medicine at Houston, TX; The Children's Memorial Hermann Hospital, Houston, - - 2014
Congenital diaphragmatic hernia (CDH) remains a significant cause of death in newborns and, despite improved outcomes with multimodality therapies, optimal timing of repair remains undefined. We sought to evaluate the influence of surgical timing on patient outcomes and hypothesized that delayed repair does not improve survival in CDH. Prospectively collected ...
Pillai Anilkumar P AP University Hospitals, Birmingham, United Kingdom ; - - 2014
Rationale It is not known how the 2011 Global Initiative on Chronic Obstructive Lung Disease (GOLD) strategy predicts clinical course of Alpha One Antitrypsin Deficiency (AATD). Objectives To determine how the new strategy relates to outcomes i.e. mortality, lung function decline and exacerbations in patients with AATD. Methods All PiZZ ...
García Callejo Francisco Javier FJ Servicio de Otorrinolaringología, Hospital Clínico Universitario de Valencia, Valencia, España. Electronic address: - - 2014
Dabigatran is a new non-vitamin K antagonist (VKA) anticoagulant with anti-thrombin action, with supposedly fewer haemorrhagic complications. However, there are actually no established agents to reverse its effect, nor specific coagulation time tests for monitoring it. An observational prospective study was developed, noting epidemiological, clinical and therapeutic features among subjects ...
Wade S W SW Wade Outcomes Research and Consulting, 358 South 700 East, Suite B-432, Salt Lake City, UT, 84013, USA, - - 2014
Persistence with postmenopausal osteoporosis (PMO) medications is not well characterized beyond 12 months. Of 3,011 postmenopausal women treated in primary care, 36.8 % continued baseline PMO medication during 36 months of follow-up. Many factors were associated with nonpersistence, including newly initiating or switching therapy, and reporting moderate to severe side effects. Persistence with ...
Franceschini M M Department of Rehabilitation, IRCCS San Raffaele--Pisana, Rome, Italy - - - 2014
BACKGROUND:Spasticity is a common disabling symptom of several neurological conditions including stroke. Botulinum toxin type A (BTX--A) injection represents the gold standard therapy for focal spasticity. Post--stroke management of patients receiving BTX--A therapy has been variously investigated, but general agreement on how and when to implement rehabilitation is lacking. To ...
Park Yongwhi Y Division of Cardiology, Department of Internal Medicine, Gyeongsang National University Hospital and Gyeongsang National University School of - - 2014
Aim: Proton pump inhibitor (PPI) therapy has been shown to attenuate the antiplatelet effects of clopidogrel. The aim of this study was to compare the antiplatelet effects of cilostazol versus clopidogrel in patients co-administered a PPI. Methods: We enrolled PPI-naïve stented patients treated with standard clopidogrel and aspirin therapy for ...
Yang Zengjie Z Ninth Department of Plastic Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, - - 2014
The purpose of this study is to survey the cepstral peak prominence (CPP) of vowel sounds and to compare objective data obtained from patients with velopharyngeal insufficiency after cleft palate surgery with objective data of those with normal healthy controls using acoustic analyzer. Participants were divided into a clinical group ...
Xu Jiarui - - 2014
Aim: The aim of this study was to compare the efficacies of goal-directed renal replacement therapy (GDRRT) and daily hemofiltration (DHF) for treating acute kidney injury (AKI) patients after cardiac surgery. In our retrospective study, we included 140 cardiac surgery AKI patients who were treated with renal replacement therapy (RRT) ...
Demirbilek Huseyin H Developmental Endocrinology Research Group, Clinical and Molecular Genetics Unit, Institute of Child Health, University College London, 30 Guilford St, London WC1N 1EH & Department of Paediatric Endocrinology, Great Ormond St Hospital for Children, London WC1N 3JH, - - 2014
Context: Octreotide, a somatostatin analogue, is commonly used in diazoxide unresponsive congenital hyperinsulinism (CHI) patients as a second line therapy. Objective: The aims of this study were to evaluate the dose range, side effects and long-term follow up of octreotide therapy in a large cohort of CHI patients. Setting: International ...
Kesikburun S S Department of PM&R, Turkish Armed Forces Rehabilitation Center, Gülhane Military Medical Academy, Ankara, Turkey, - - 2014
Myasthenia gravis is an important indication for the long-term prescription of corticosteroids. We present a patient with myasthenia gravis who had worsening of symptoms associated with the use of alendronate. A 24-year-old patient with myasthenia gravis had been administered oral systemic corticosteroid (deflazacort 40 mg/day) for 3 years in order to control ...
Yang Shuofei S Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, No. 305 East Zhongshan Road, Nanjing, 210002, Jiangsu, People's Republic of China, - - 2014
To assess the feasibility, effectiveness, and safety of catheter-directed thrombolysis and aspiration thrombectomy therapy by combined route of superior mesenteric vein and artery (SMV+SMA) for acute superior mesenteric venous thrombosis (ASMVT). This retrospective study reviewed eight ASMVT patients with transcatheter direct thrombolysis and aspiration thrombectomy therapy via SMV and indirect ...
Mansour Ahmad M AM Departments of Ophthalmology, American University of Beirut and Rafic Hariri University Hospital, Beirut, Lebanon. Electronic address: - - 2014
Paraproteinemia relates to monoclonal gammopathy-producing pathologic antibodies with serous macular detachment being an uncommon ocular manifestation. We ascertained the clinical course of maculopathy in paraproteinemia and investigated the effect of various therapeutic methods on the resolution of subretinal deposits. Multicenter, retrospective, observational case series. The records of patients with paraproteinemia with ...
Akamatsu S S Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima, Japan; Liver Research Project Center, Hiroshima University, Hiroshima, Japan; Laboratory for Digestive Diseases, SNP Research Center, The Institute of Physical and Chemical Research (RIKEN), Hiroshima, - - 2014
Treatment success of chronic hepatitis C virus genotype 1 infection has improved with the advent of telaprevir plus peg-interferon/ribavirin triple combination therapy. However, the effect of inosine triphosphatase (ITPA) polymorphism on dose reduction during triple therapy, especially during the postmarketing phase, has not been sufficiently evaluated. We analysed 273 patients ...
Tomisti Luca L L Tomisti, Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Pisa, pisa, 56124, - - 2014
Considering the different pathogenic mechanism of the two main forms of amiodarone-induced thyrotoxicosis (AIT) we ascertained whether this results in a different onset time as well. We retrospectively analyzed the clinical records of 200 consecutive AIT patients (157 men, 43 women; mean age 62.2±12.6 years) referred to our Department from ...
Ma Margaret H Y MH From the Academic Department of Rheumatology, King's College London School of Medicine, London, UK. Supported by the UK National Institute of Health Research (DRF-2009-02-86 to M.H.Y. Ma) and Arthritis Research UK (Grant Reference Number 19739 to I.C. Scott). M.H.Y. Ma, BSc, MBBS, MSc, MRCP; I.C. Scott, MBChB, MRCP, MSc; C. Dahanayake, BSc; A.P. Cope, BSc, PhD, MBBS, FRCP; D.L. Scott, BSc, MD, FRCP, Academic Department of Rheumatology, King's College London School of Medicine. Address correspondence to Dr. M.H.Y. Ma, Department of Rheumatology, King's College London School of Medicine, Weston Education Centre, King's College London, 10 Cutcombe Road, London SE5 9RS, UK. E-mail: margaret.ma@nhs.net. Accepted for publication March 14, - - 2014
Early intensive treatment is now the cornerstone for the management of rheumatoid arthritis (RA). In the era of personalized medicine, when treatment is becoming more individualized, it is unclear from the current literature whether all patients with RA benefit equally from such intensive therapies. We investigated the benefit of different ...
Linder Brian J BJ Department of Urology, Mayo Clinic, Rochester, - - 2014
To evaluate the clinical presentation, management and outcomes for patients undergoing cystectomy for refractory hemorrhagic cystitis. We identified 21 patients with refractory hematuria treated with cystectomy at our institution between 2000-2012. Prior to cystectomy, all patients had failed clot evacuation, bladder fulguration, and bladder irrigation. Additionally, 45% had received prior ...
Kang Kyu Keun KK Kyu Keun Kang, Dong Ho Lee, Dong Hyun Oh, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Nayoung Kim, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeongi-do 463-707, South - - 2014
To investigate moxifloxacin-containing triple therapy as second-line treatment for Helicobacter pylori (H. pylori) infection following failed first-line treatment. The sample included 312 patients for whom first-line treatment failed between January 2008 and May 2013; 27 patients were excluded, and a total of 285 patients received 7- or 14-d moxifloxacin-containing triple ...
Sanford Mark M Adis, Level 1, 5 The Warehouse Way, Northcote 0627; Private Bag 65901, Mairangi Bay, 0754, Auckland, New Zealand, - - 2014
Human immunoglobulin is an established replacement therapy for patients with primary immunodeficiency disorders (PIDs). Recombinant human hyaluronidase (rHuPH20) is a spreading factor that temporarily digests hyaluronan in the skin interstitium enabling large volumes of fluid or drug solutions to be infused and absorbed subcutaneously. HyQvia(®) (IGHy) is a new combination ...
Boutroux Helene H Pediatric, adolescent and young adult oncology department, Institut Curie, Paris, - - 2014
Orbital rhabdomyosarcoma (ORMS) is associated with an excellent survival rate greater than 85%, and is considered to be a favourable site for this tumour. Treatment is based on combination chemotherapy together with best local therapy, sometimes surgery but more often radiation therapy. Local therapy is associated with frequent and potentially ...
Orbegozo Cortes D D Intensive Care Department, Hôpital Erasme, Université Libre de Bruxelles (ULB),Brussels, Brussels, Belgium - - - 2014
Fluid therapy is widely used in critically ill patients to restore effective intravascular volume and improve organ perfusion. Recent studies have questioned the administration of colloid-based solutions, especially if containing hydroxyethyl starch (HES), in different ICU populationsÍž however, there is still uncertainty on the use of colloids as initial fluid ...
Linnér Anna A Department of Medicine Huddinge, Center for Infectious Medicine, Karolinska Institutet, Stockholm, - - 2014
 Streptococcal toxic shock syndrome (STSS) and necrotizing fasciitis are the two most severe invasive manifestations caused by group A streptococcus (GAS). Intravenous immunoglobulin (IVIG) therapy has been suggested as adjunctive treatment with a beneficial effect on mortality. However the clinical evidence is limited. Here we aim to further document the ...
Jiménez-Varo E - - 2014
Vitamin K antagonists (VKAs) remain as the most prescribed drug for treatment and prevention of thrombotic disorders in many countries, despite the recent approval of the new oral anticoagulants (NOACs). Although effectiveness and safety of VKAs are tightly associated to maintaining the patient within the international normalised ratio (INR) therapeutic ...
Nauck Michael A MA Diabetes Centre, Bad Lauterberg, - - 2014
To assess long-term glycaemic durability, safety and tolerability of dapagliflozin versus glipizide as add-on therapies in patients with type 2 diabetes inadequately controlled on metformin. Research Design And Methods This was a 52-week, randomized, double-blind study of dapagliflozin (n = 406) versus glipizide (n = 408), up-titrated over 18 weeks according to tolerability and ...
Konstas Anastasios G P AG 1st University Department of Ophthalmology, Aristotle University of Thessaloniki, 1 Kyriakidi Street, 546 36, Thessaloniki, Greece, - - 2014
To compare the 24-h intraocular pressure (IOP) control and tolerability of travoprost/timolol benzalkonium chloride (BAK)-free (TTFC) vs. latanoprost/timolol fixed combination preserved with BAK (LTFC) in open-angle glaucoma patients insufficiently controlled with latanoprost 0.005% monotherapy given once in the evening. The authors have conducted a prospective, observer-masked, active-controlled, cross-over, comparison study. ...
Zhu Xianmin X Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, - - 2014
Severe aplastic anemia (SAA), which is considered to be an immune-mediated destruction of bone marrow stem cells with pancytopenia and hypoplasia, can be successfully treated with immunosuppressive therapy or hematopoietic stem cell transplantation (HSCT). Between January 2009 and December 2012, thirteen patients diagnosed with SAA were treated with tacrolimus plus ...
Schaeffer David F DF Department of Laboratory Medicine and Pathology, Mount Sinai Hospital, Toronto, ON, Canada Joseph and Wolf Lebovic Health Complex 600 University Avenue Toronto, Ontario, Canada M5G 1X5; Department of Pathology and Laboratory Medicine, The University of British Columbia, Vancouver, BC, Canada 910 W. 10th Avenue, Vancouver, British Columbia, Canada V5Z 1M9. Electronic address: - - 2014
Anti-tumor necrosis factor α (anti-TNF-α) therapy can result in endoscopic healing, reduction of symptoms, and reduced need for surgery and hospitalization in many patients with Crohn's disease (CD). Earlier data suggested that anti-TNF-α therapy may be associated with fibrosis and stricturing. We sought to determine whether anti-TNF-α therapy affects histologic ...
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