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Silveira V V Oral and maxillofacial Department Pontifícia Universidade do Rio Grande do Sul (PUCRS) Porto Alegre, RS, Brazil - - - 2014
Aim: The objective of this study was to compare integration of AlloDerm® acellular dermal grafts in animals subjected to non-ablative laser irradiation and animals not exposed to this therapy. Methods: Standardized AlloDerm® fragments measuring 5 mm² were grafted into the subcutaneous tissue overlying the calvaria in 32 Wistar rats. Laser ...
Springer Jason J From Department of Rheumatic and Immunologic Diseases (JS); Department of Quantitative Health Sciences (BN); and Center for Vasculitis Care and Research, Department of Rheumatic and Immunologic Diseases (CAL, GSH, AVF), Cleveland Clinic, Cleveland, Ohio. *Current affiliation: University of Kansas Medical Center, Kansas City, - - 2014
To determine outcomes in relation to duration of maintenance therapy in patients with granulomatosis with polyangiitis (Wegener's) (GPA), we conducted a retrospective chart review of patients with GPA seen at a single vasculitis center from 1992 to 2010. All patients achieved remission defined by a Birmingham Vasculitis Activity Score for ...
Kumar Santosh S Department of Urology, PGIMER (Postgraduate Institute of Medical Education and Research), Chandigarh, - - 2014
To compare the safety and efficacy of tamsulosin and tamsulosin with the phosphodiesterase-5 inhibitor tadalafil in combination with prednisolone as medical expulsive therapies for lower ureteric stones. Between July 2011 and December 2012, 62 adult patients presenting with distal ureteric stones sized 5 to 10 mm were randomized equally to ...
Olfat Mohammed M The Hospital for Sick Children, Toronto, - - 2014
Cytopenias including thrombocytopenia and autoimmune hemolytic anemia(AIHA) are common in childhood-onset SLE (cSLE) and may be refractory to conventional therapy with corticosteroids, IVIG and/or other immunosuppressives. Rituximab appears to be an effective therapy for cytopenias, although no long term studies have been completed, and few cSLE patients have been reported. ...
Fogel Itay I Schneider Children's Medical Center, Tel Aviv University, Petach Tikvah, - - 2014
In our previous prospective study we have demonstrated that the administration of Dexamethasone as an adjuvant therapy lead to a significant clinical and laboratory improvement in children with septic arthritis. This therapy has become accepted in some of the pediatric wards at Schneider's medical center. The aim of this study ...
Lovell Daniel J DJ Cincinnati Children's Hospital Medical Center, Cincinnati, - - 2014
Treatment with anti-TNF therapies (anti-TNF) for polyarticular forms (extended oligo, Poly RF +/-) of JIA (PF-JIA) results in >50% demonstrating clinically inactive disease (CID). The aims of this study were to determine the frequency, timing and predictors of flare upon withdrawal of anti-TNF in PF-JIA in CID. In 16 centers ...
Gasparovic Hrvoje H Department of Cardiac Surgery, University Hospital Center Zagreb, University of Zagreb, Zagreb, Croatia. Electronic address: - - 2014
Coronary artery bypass grafting is pivotal in the contemporary management of complex coronary artery disease. Interpatient variability to antiplatelet agents, however, harbors the potential to compromise the revascularization benefit by increasing the incidence of adverse events. This study was designed to define the impact of dual antiplatelet therapy (dAPT) on ...
Mohammed R H A RH Rheumatology and Rehabilitation, School of Medicine, Cairo University Hospitals, Cairo, Egypt, - - 2014
The goal of the present study was to prospectively assess the long-term clinical outcome of biologic modifying drug therapy in a population of Saudi rheumatoid arthritis (RA) patients. This is the first prospective, long-term report on the efficacy and safety of biologic therapy in Saudi RA patients. It is a ...
Mamchur Sergey E - - 2014
The aim of the study was to compare the efficacy of pulmonary vein antrum isolation (PVAI), extended PVAI and ganglionic plexi (GP) ablation in persistent AF. One hundred and twenty patients 56.2 ± 8.8 years old were randomized into three groups: GP ablation (n = 37), PVAI (n = 42), ...
Lynde Chuck W CW University of Toronto, Toronto, Ontario, - - 2014
Introduction: Ceramide-containing moisturizers may offer benefits as an adjunct to acne treatment. Methods: An expert panel of 11 Canadian dermatologists, including an international clinical scientist, used the following modified Delphi process: 1) A systematic literature review for acne treatment, dry skin, irritation, depletion of ceramides in acne, and benefits of ...
Rayegani S M SM Physical Medicine & Rehabilitation Department, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, - - 2014
Purpose: The aim of the present study was to evaluate the effect of applying electroencephalogram (EEG) biofeedback (neurobiofeedback) or electromyographic (EMG) biofeedback to conventional occupational therapy (OT) on improving hand function in stroke patients. Methods: This study was designed as a preliminary clinical trial. Thirty patients with stroke were entered ...
Maleki Masoud M Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, - - 2014
Systemic oral psoralens plus UVA therapy (PUVA) is a therapeutic method used with considerable success in many different skin disorders. PUVA therapy causes some cutaneous and noncutaneous side effects and in the present research we deal with cutaneous side effects. Evaluation of patients to know the different skin side effects ...
Thornton Paul - - 2014
Although gonadotropin-releasing hormone agonists (GnRHa) have been the standard of care of central precocious puberty (CPP) management for many years, there are still questions about the long-term consequences of treatment. With increased utilization of GnRHa treatment, it is now possible to assess posttreatment outcomes in the immediate posttreatment period and ...
Driver Vickie R VR Department of Surgery, Veterans Affairs New England Health Care Division, Providence, - - 2014
Background : We conducted a post-hoc retrospective analysis of patients enrolled in a randomized controlled trial to evaluate overall costs of negative pressure wound therapy (NPWT; V.A.C. Therapy; KCI USA, Inc, San Antonio, Texas) versus advanced moist wound therapy (AMWT) in treating grade 2 and 3 diabetic foot wounds during ...
Abu-El-Haija Maisam M *Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA †University of Iowa Roy J. & Lucille A. Carver College of Medicine, Iowa City, Iowa, USA ‡Division of Pediatric Gastroenterology, Department of Pediatrics, University of Iowa Children's Hospital, Iowa City, Iowa, - - 2014
Parenteral nutrition is essential for the growth and nutrition of patients with intestinal failure (IF). Catheter related blood stream infections (CRBSI) are a major complication of parenteral nutrition use. Few retrospective studies have shown that 70% Ethanol lock (ETL) therapy for central lines can reduce the infection rate. Studies assessing ...
Zhu Wei W Shanghai Key Laboratory for Endocrine Tumors, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases and Shanghai E-institute for Endocrinology, Ruijin Hospital, Shanghai Jiaotong University, School of Medicine, 197 Ruijin second Rd, Shanghai 200025 - - 2014
Background: For patients with active moderate-to-severe Graves' ophthalmopathy (GO), a course of 4.5 g intravenous (iv) glucocorticoids (GC) is the recommended therapy. The weekly protocol is preferred because of the potential safety concerns with the daily protocol. However, evidence for the superiority of different administration protocols is lacking. Methods: We ...
Narayan Sanjiv M SM Department of Medicine, University of California, San Diego; Veterans Affairs Medical Center, San Diego. Electronic address: - - 2014
To determine if ablation that targets patient-specific AF-sustaining substrates (rotors or focal sources) is more durable than trigger ablation alone at preventing late AF recurrences. Late recurrence substantially limits the efficacy of pulmonary vein (PV) isolation for AF, and is associated with PV reconnection and the emergence of new triggers. ...
Ribeiro Priscila W PW Neurology Service, Botucatu School of Medicine, University Estadual Paulista Júlio de Mesquita Filho, São Paulo, - - 2014
The high prevalence of dysphagia after stroke leads to increased mortality, and cerebral reperfusion therapy has been effective in reducing neurologic deficits. The aim of this study was to investigate the severity and evolution of dysphagia and the occurrence of pneumonia in patients submitted to cerebral reperfusion therapy. Seventy ischemic ...
Byun Jeik J 0000-0002-3405-5945 Department of Surgery, Seoul National University College of Medicine, Seoul, - - 2014
Liver transplantation (LT) has been the key therapy for end stage liver diseases. However, LT in infancy is still understudied. From 1992 to 2010, 152 children had undergone LT in Seoul National University Hospital. Operations were performed on 43 patients aged less than 12 months (Group A) and 109 patients ...
Cho Yun-Kyeong YK Division of Cardiology, Keimyung University Dongsan Medical Center, Daegu, - - 2014
Combination single-pill therapy can improve cost-effectiveness in a typical medical therapy. However, there is a little evidence about the efficacy and tolerability of combination single-pill antiplatelet therapy after percutaneous coronary intervention (PCI) with drug-eluting stents (DES). From June to November 2012, in total, 142 patients who met the following criteria ...
Louis Scott G SG Trauma Research Institute of Oregon, Oregon Health & Science University, - - 2014
IMPORTANCE Enoxaparin sodium is widely used for deep vein thrombosis (DVT) prophylaxis, yet DVT rates remain high in the trauma and general surgery populations. Missed doses during hospitalization are common. OBJECTIVE To determine if missed doses of enoxaparin correlate with DVT formation. DESIGN, SETTING, AND PARTICIPANTS Data were prospectively collected ...
Muhammad Omid H OH Laboratory of Buccal Health and Aging, URE 001, Faculty of - - 2014
Photodynamic Therapy was introduced as an adjuvant to conventional chemo-mechanical debridement during endodontic treatment to overcome the persistence of biofilms. The aim of this study was to evaluate the ability of Photodynamic Therapy (PDT) to disrupt an experimental microbial biofilm inside the root canal in a clinically applicable working time. ...
Rajasekaran Surender S 1Pediatric Critical Care Medicine, Helen DeVos Children's Hospital. Grand Rapids, MI. 2Grand Rapids Medical Education Partners, Grand Rapids, MI. 3Department of Rheumatology, Helen DeVos Children's Hospital. Grand Rapids, - - 2014
Secondary hemophagocytic lymphohistiocytosis, macrophage activating syndrome, and sepsis share the same inflammatory phenotype leading often to multiple organ dysfunction syndrome needing intensive care. The goal of this article is to describe our experience with anakinra (Kineret), a recombinant interleukin-1 receptor antagonist, in decreasing the systemic inflammation. Retrospective case series. The ...
Shams Pari N PN Department of Ophthalmology and Visual Sciences, Vancouver Hospital Eye Care Centre and University of British Columbia, Vancouver, - - 2014
To compare the risk of developing compressive optic neuropathy in patients with active thyroid eye disease (TED) treated with corticosteroids with or without orbital radiotherapy. Retrospective single center case control study. The clinical charts of 351 patients with active TED who received corticosteroids with or without orbital radiotherapy between 1999 ...
Kurz Mario - - 2014
Endocarditis due to Propionibacterium acnes is a rare disease. Scant data on treatment of these infections is available and is based on case reports only. If the disease is complicated by abscess formation, surgical intervention combined with an antibiotic therapy might improve clinical outcome. In some cases, cardiac surgeons are ...
Said Dalia G DG Research Institute of Ophthalmology, Cairo, - - 2014
To investigate the efficacy and safety of corneal collagen cross-linking (CXL) with photoactivated riboflavin (photoactivated chromophore for infectious keratitis [PACK]-CXL) in the management of infectious keratitis with corneal melting. Prospective clinical trial. Forty eyes from 40 patients with advanced infectious keratitis and coexisting corneal melting. Twenty-one patients (21 eyes) underwent ...
Wang Kaidi - - 2014
To report the clinical outcomes in Chinese patients with primary open-angle glaucoma and ocular hypertension treated with bimatoprost 0.03% therapy. Two hundred sixty-three Chinese patients with primary open-angle glaucoma and ocular hypertension who needed initial or additional intraocular pressure (IOP) lowering were recruited in this prospective, open-label, multicenter clinical study ...
Subramaniam Kavitha K Gastroenterology and Hepatology Unit, The Canberra Hospital, Garran, ACT, - - 2014
Anti-tumour necrosis factor (TNF) agents are used as induction and maintenance therapy in ulcerative colitis (UC) refractory to standard therapy and as rescue therapy in acute severe ulcerative colitis (ASUC). To determine long-term outcomes including colectomy rates, predictors of maintenance of response and remission, risk of serious adverse events by ...
Brito Graça G Serviço de Imunologia, Complexo Hospitalar Universitário Professor Edgard Santos, Salvador, Bahia, Brazil; National Institute of Science and Technology-Tropical Disease, Instituto de Ciências da Saúde da Universidade Federal da - - 2014
Pentoxifylline is a tumor necrosis factor-α (TNF-α) inhibitor that also attenuates the immune response and decreases tissue inflammation. The association of pentoxifylline with antimony improves the cure rate of mucosal and cutaneous leishmaniasis. In this randomized and double blind pilot trial, cure rate was higher, although not significant, in patients ...
Sahin M M Department of Otolaryngology, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, - - 2014
One method of speech rehabilitation following total laryngectomy surgery is esophageal speech therapy (EST). In this method, which has witnessed relatively low success rates at the end of therapy, identification of patients who can benefit from EST beforehand will be important for determining the appropriate method for alaryngeal speech rehabilitation ...
Sturm Sarah M SM St. Mary's Medical Center, Huntington, WV, - - 2014
Case report. Reports of comprehensive rehabilitation following hand replantation are limited. To describe hand therapy of a patient following hand replantation. Right hand dominant 55 year-old male assessed 9 days following left hand replantation to treat distal forearm amputation. Patient presented with dorsal blocking orthotic. Initial status: AROM digits and ...
Wada Masanori M Department of Neurosurgery, Chiba Rehabilitation Center, 1-45-2 Hondacho, Midori-ku, Chiba-shi, Chiba 266-0005, Japan. Electronic address: - - 2014
The present study tested the hypothesis of whether antiplatelet agents (APA) induce chronic subdural hematoma (CSDH) recurrence via a platelet aggregation inhibitory effect. We examined risk factors for CSDH recurrence, focusing on APA, in 719 consecutive patients who admitted to three tertiary hospitals and underwent burr-hole craniostomy and irrigation for ...
Bae Ikyul I Kunsan College of Nursing, Kunsan, South Korea. Electronic address: - - 2014
The aim of this study was to investigate the effects of intraoperative music listening on anxiety, the BIS index, and the vital signs of patients undergoing regional anesthesia in an operating room. Eighty patients who were scheduled for a surgery that would use regional anesthesia were allocated to either the ...
Watanabe Naohiro N Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, - - 2014
Background: The optimal treatment method for interstitial pneumonia (IP) with connective tissue disease (CTD) remains controversial. In addition, a clinically meaningful end point to judge drug efficacy has not been fully investigated. Objectives: The aim of this study was to evaluate, from various aspects, the therapeutic benefit and tolerability of ...
Yu Yinan Y Department of Anesthesiology, Shanghai Jiaotong University Affiliated Shanghai First People's Hospital, Shanghai, - - 2014
Pleth variability index (PVI), a noninvasive dynamic indicator of fluid responsiveness has been demonstrated to be useful in the management of the patients with goal directed fluid therapy under general anesthesia, but whether PVI can be used to optimize fluid management under combined general and epidural anesthesia (GEN-EPI) remains to ...
Kolbe Maria F MF Dental Research Division, School of Dentistry, Paulista University, São Paulo, São Paulo, - - 2014
Background: This study investigated the effect of photodynamic therapy (PDT) as monotherapy during supportive periodontal therapy. Methods: A split-mouth, randomized controlled trial was conducted in chronic periodontitis patients (n=22) presenting at least three residual pockets [probing depth>5mm with bleeding upon probing (BoP)]. The selected sites randomly received: 1) PDT, 2) ...
Vazquez Jose - - 2014
Hospitalized patients are at increased risk for candidemia and invasive candidiasis (C/IC). Improved therapeutic regimens with enhanced clinical and pharmacoeconomic outcomes utilizing existing antifungal agents are still needed. An open-label, non-comparative study evaluated an intravenous (IV) to oral step-down strategy. Patients with C/IC were treated with IV anidulafungin and after ...
Jorde Ulrich P - - 2014
A post approval (PA) study for destination therapy (DT) was required by FDA to determine whether results with the HeartMate (HM) II Left Ventricular Assist Device (LVAD) in a commercial setting are comparable to results during the DT multicenter pivotal clinical trial. New device technology developed in the clinical research ...
Hoshino Makoto M Department of Respiratory Medicine, Atami Hospital, International University of Health and Welfare, Atami, - - 2014
Combining a long-acting muscarinic antagonist with a long-acting β2 -agonist has been shown to be pharmacologically useful in patients with chronic obstructive pulmonary disease (COPD). The aim of the present study was to evaluate the effectiveness of the dual bronchodilator therapy on airway dimensions in COPD. Patients (n = 54) were randomly ...
Costantini Elisabetta E Urology Department, University of Perugia, S. M. Misericordia Hospital, S. Andrea delle Fratte, 06123, Perugia, - - 2014
This multicentre, randomised, non-blinded, parallel group study is designed to assess the null hypothesis that a 3-month prophylactic schedule with fosfomycin is not inferior to prulifloxacin in reducing the number of urinary tract infection episodes during and after prophylaxis in female patients with recurrent urinary tract infections (rUTIs). One hundred ...
Landis Erin T ET Department of Dermatology, Wake Forest School of Medicine , Winston-Salem, NC , USA - - 2014
Abstract Background: Pyoderma gangrenosum (PG) often necessitates long-term immunosuppressant therapy. Many patients may receive treatment for longer periods and higher doses than is clinically necessary because clinicians may have difficulty differentiating between active disease and an inactive residual ulcer that is often slow to heal. Objective: Recognition of the correct ...
Suzuki Satoshi S 1Department of Intensive Care, Austin Hospital, Heidelberg, VIC, Australia. 2Australian and New Zealand Intensive Care Research Centre, Melbourne, VIC, - - 2014
To assess the feasibility and safety of a conservative approach to oxygen therapy in mechanically ventilated ICU patients. Pilot prospective before-and-after study. A 22-bed multidisciplinary ICU of a tertiary care hospital in Australia. A total of 105 adult (18 years old or older) patients required mechanical ventilation for more than ...
Spethmann Sebastian S Medizinische Klinik für Kardiologie und Angiologie, Campus Mitte, Charité-Universitätsmedizin Berlin, Charitéplatz 1, Berlin, 10117, Germany, - - 2014
Atrial fibrillation (AF) is a common arrhythmia with relevant impact on mortality and morbidity. Pulmonary vein isolation (PVI) is an established therapy in patients who remain symptomatic under optimal medical therapy. However, up to 70 % of patients present with recurrence of AF after PVI. Therefore, identifying ideal candidates is an ...
Levin Ethan E Department of Dermatology, Psoriasis and Skin Treatment Center, University of California , San Francisco, CA , USA - - 2014
Abstract Background: The combination of phototherapy and topical therapy is one of the most widely used treatment modalities for moderate to severe psoriasis. The development of targeted phototherapy with excimer laser and new topical spray formulations has made these therapies both more convenient and more effective. In this open label ...
Bardou-Jacquet Edouard E aLiver Unit, CHU Rennes bINSERM U991 cINSERM CIC 0203, Pontchaillou Hospital dUniv Rennes1, UFR Medicine, Rennes, - - 2014
Initial venesection therapy in dysmetabolic iron overload syndrome (DIOS) was shown to improve insulin resistance. However, no data are available on the long-term outcome of iron store, thus questioning the relevance of maintenance therapy. The aim of the study was to describe the long-term evolution of iron overload after successful ...
Krewer Carmen C Schoen Klinik Bad Aibling, Motor research department, Kolbermoorer Strasse 72, D-83043, Bad Aibling, Germany. Electronic address: - - 2014
The aim of this study was to investigate short-term and long-term effects of repetitive peripheral magnetic stimulation (rpMS) on spasticity and motor function. monocentric randomized, double-blind, sham-controlled trial. neurologic rehabilitation hospital PARTICIPANTS: 66 patients with severe hemiparesis and mild to moderate spasticity due to a stroke or a traumatic brain ...
Resnick Karen A KA Long Beach Veterans Administration Health Care System and Department of Surgery, University of California - - 2014
The vasodilator cilostazol (Pletal®), a phosphodiesterase 3 inhibitor, is approved in the United States for treatment of intermittent claudication. This study was aimed at evaluating its efficacy as an adjunct in the management of arterial ulceration. The clinical records of patients treated with cilostazol from 2000 to 2010 at one ...
Jang Min Uk MU Department of Neurology, Hallym University Sacred Heart Hospital, Chuncheon, - - 2014
Recent methodological advances in recanalization therapy may alter recanalization strategies and clinical outcomes in patients with symptomatic occlusion of intracranial cerebral arteries. However, few studies have analyzed these changes at a national level, with none conducted in Korea. On the basis of a prospective multicenter stroke registry database in Korea, ...
Bektas Omer - - 2014
Our aim is to present the etiology and risk factors for cerebral sinovenous thrombosis (CSVT) and the radiological findings, anticoagulant therapy used, and treatment outcome of patients with CSVT. This study included 12 patients who were treated for CSVT at the Ankara University, School of Medicine, Department of Pediatric Neurology. ...
Vahabnezhad Elaheh E *Division of Pediatric Gastroenterology, University of California, Los Angeles, California; and †Pediatric Inflammatory Bowel Disease Center, Cedars Sinai Medical Center, Los Angeles, - - 2014
Despite increasing use of infliximab (IFX) in children with Crohn's disease (CD) and ulcerative colitis (UC), long-term durability and safety of IFX beyond 1 year is limited in pediatric inflammatory bowel disease. We performed a 10-year single-center retrospective cohort study of 188 patients initiating IFX at <21 years of age ...
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