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Konstas Anastasios G P AG 1st University Department of Ophthalmology, Aristotle University of Thessaloniki, 1 Kyriakidi Street, 546 36, Thessaloniki, Greece, - - 2014
To compare the 24-h intraocular pressure (IOP) control and tolerability of travoprost/timolol benzalkonium chloride (BAK)-free (TTFC) vs. latanoprost/timolol fixed combination preserved with BAK (LTFC) in open-angle glaucoma patients insufficiently controlled with latanoprost 0.005% monotherapy given once in the evening. The authors have conducted a prospective, observer-masked, active-controlled, cross-over, comparison study. ...
Zhu Xianmin X Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, - - 2014
Severe aplastic anemia (SAA), which is considered to be an immune-mediated destruction of bone marrow stem cells with pancytopenia and hypoplasia, can be successfully treated with immunosuppressive therapy or hematopoietic stem cell transplantation (HSCT). Between January 2009 and December 2012, thirteen patients diagnosed with SAA were treated with tacrolimus plus ...
Schaeffer David F DF Department of Laboratory Medicine and Pathology, Mount Sinai Hospital, Toronto, ON, Canada Joseph and Wolf Lebovic Health Complex 600 University Avenue Toronto, Ontario, Canada M5G 1X5; Department of Pathology and Laboratory Medicine, The University of British Columbia, Vancouver, BC, Canada 910 W. 10th Avenue, Vancouver, British Columbia, Canada V5Z 1M9. Electronic address: - - 2014
Anti-tumor necrosis factor α (anti-TNF-α) therapy can result in endoscopic healing, reduction of symptoms, and reduced need for surgery and hospitalization in many patients with Crohn's disease (CD). Earlier data suggested that anti-TNF-α therapy may be associated with fibrosis and stricturing. We sought to determine whether anti-TNF-α therapy affects histologic ...
Hwang Gyojun G From the Department of Neurosurgery, Seoul National University Bundang Hospital, 300 Gumi-dong, Bungdang-gu, Seongnam, Gyeonggi 463-707, Korea (G.H., N.M.P., S.J.P., E.A.J., O.K.K.); Department of Neurosurgery, New Korea Hospital, Gimpo, Korea (J.G.K., K.S.S.); Department of Neurosurgery, Pohang Stroke and Spine Hospital, Pohang, Korea (Y.J.L.); Department of Neuroscience, Section of Neurosurgery, Makati Medical Center, Makati, Philippines (J.B.V.); and Department of Neurosurgery, Airlangga University, Dr Sutomo General Hospital, Surabaya, Indonesia - - 2014
Purpose To evaluate characteristics of delayed ischemic stroke after stent-assisted coil placement in cerebral aneurysms and to determine the optimal duration of dual antiplatelet therapy for its prevention. Materials and Methods This retrospective study was approved by the institutional review board, and the requirement to obtain written informed consent was ...
Nishizawa Toshihiro T *Division of Gastroenterology, National Hospital Organization, Tokyo Medical Center †Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine ∥∥∥Department of Pharmacy, National Center for Global Health and Medicine, Tokyo ‡Division of Gastroenterology, National Hospital Organization, Kyoto Medical Center, Kyoto §Division of Gastroenterology, National Hospital Organization, Mie Central Medical Center, Mie ∥Division of Gastroenterology, National Kyushu Medical Center, Fukuoka ¶Division of Gastroenterology, National Hospital Organization, Saitama National Hospital, Wako #Division of Gastroenterology, National Hospital Organization, Beppu Medical Center, Beppu **Division of Gastroenterology, National Hospital Organization, Osaka Medical Center †††Division of Gastroenterology, National Hospital Organization, Osaka Minami Medical Center, Kawachinagano, Osaka ††Division of Gastroenterology, National Hospital Organization, Kanazawa Medical Center, Kanazawa, Ishikawa §§Division of Gastroenterology, National Hospital Organization, Fukuyama Medical Center ##Division of Gastroenterology, National Hospital Organization, Kure Medical Center, Hiroshima ∥∥Division of Gastroenterology, National Hospital Organization, Okayama Medical Center, Okayama ¶¶Division of Gastroenterology, National Hospital Organization, Asahikawa Medical Center, Asahikawa §§§Division of Gastroenterology, National Hospital Organization, Hokkaido Medical Center, Sapporo, Hokkaido ***Division of Gastroenterology, National Hospital Organization, Yonago Medical Center, Yonago, Tottori, Japan ‡‡Division of Gastroenterology, Kochi National Hospital, Kochi ‡‡‡Division of Gastroenterology, National Hospital Organization, Matsumoto Medical Center, Mesa, Matsumoto; - - 2014
Helicobacter pylori eradication rates achieved with a first-line regimen of clarithromycin (CLR) combined with amoxicillin (AMX) and a proton pump inhibitor have recently fallen to ≤80% because of the increasing incidence of CLR resistance in Japan. This randomized multicenter trial aimed to compare the eradication success of 2 first-line triple ...
Martín-Merino Elisa E Spanish Centre for Pharmacoepidemiologic Research (CEIFE), Almirante 28-2, 28004, Madrid, - - 2014
In this retrospective database study, carried out using The Health Improvement Network, a UK primary care database, we followed up patients who were prescribed low-dose acetylsalicylic acid (ASA) (75-300 mg/day) for the secondary prevention of cardiovascular disease in 2000-2007, and who discontinued therapy for a period of at least 90 days during ...
Roblin Xavier X Service de Gastrologie-Entérologie-Hépatologie, CHU de Saint-Etienne, Saint-Etienne, - - 2014
OBJECTIVES:Several decision algorithms based on the measurement of infliximab (IFX) trough levels and antibodies to IFX have been proposed. Whether such algorithms can be extrapolated to the pharmacokinetics of adalimumab (ADA) has yet to be determined.METHODS:A prospective study included all consecutive patients with inflammatory bowel disease (IBD) having a disease ...
Loftus Edward V EV Jr *Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnestota; †Health Economics, RTI Health Solutions, Research Triangle Park, North Carolina; and ‡Global Health Economics and Outcomes Research, Bristol Myers Squibb Company, Princeton, New - - 2014
Immunomodulator (IM) treatments in ulcerative colitis (UC) are not curative and carry increased risk of complications, sometimes leading to therapy changes, reduced treatment benefits, and eventual relapse. We assessed patterns of IM utilization and therapy changes, complications, and disease relapse in a real-world population of patients with moderate-to-severe UC. Claims ...
Pd Med Collaborative - - 2014
Whether initial treatment for Parkinson's disease should consist of levodopa, dopamine agonists, or monoamine oxidase type B inhibitors (MAOBI) is uncertain. We aimed to establish which of these three classes of drug, as initial treatment, provides the most effective long-term control of symptoms and best quality of life for people ...
Yadav N N Department of Periodontics, Maulana Azad Institute of Dental Sciences, New Delhi, - - 2014
The aim of this study was to evaluate lactoferrin quantification as a sensitive and objective method of detecting the degree of periodontal inflammation, oxidative stress and to monitor the effects of periodontal therapy. Fifty subjects were divided into two groups based on gingival index, probing pocket depth, clinical attachment loss ...
Vora Ajay A Sheffield Children's Hospital, Sheffield, UK. Electronic address: - - 2014
No randomised study has shown whether stratification of treatment by minimal residual disease (MRD) response improves outcome in children and young people with acute lymphoblastic leukaemia (ALL). We assessed whether children and young people with clinical standard and intermediate-risk ALL who have persistent MRD at the end of induction therapy ...
Margolis Jay M JM Truven Health Analytics, Bethesda, - - 2014
IMPORTANCE To our knowledge, the current study is the first to describe antiepileptic drug (AED) combination therapy patterns according to their mechanism of action (MOA) in a real-world setting and to evaluate the differences in outcomes comparing different-MOA combination therapy with same-MOA combination therapy for patients with partial-onset seizure. OBJECTIVE ...
Moursy Essam Eldin S EE Urology Department, Sohag Faculty of Medicine , Sohag , - - 2014
Abstract Objective. Monosymptomatic nocturnal enuresis (MNE) is a common sociomedical problem affecting children that may persist until adulthood despite various lines of therapy. The aim of this study was to assess the efficacy of combined laser acupuncture and desmopressin in managing patients with resistant MNE, compared with their efficacy when ...
Testa Giuseppina G Department of Pediatric Cardiac Anesthesia and Intensive, Children's Hospital Bambino Gesu', Rome, - - 2014
The aim of this study was to compare high-flow nasal cannula (HFNC) and conventional O2 therapy (OT) in paediatric cardiac surgical patients; the primary objective of the study was to evaluate whether HFNC was able to improve PaCO2 elimination in the first 48 h after extubation postoperatively. We conducted a ...
Ziyao Li L Department of Urology, First Affiliated Hospital of Dalian Medical University, Zhong Shan Road, No. 222, 116011, Dalian, - - 2014
This study aims to investigate the safety and efficiency of the holmium laser therapy in extramammary Paget's disease. The clinical data of 61 patients was collected since 2002 to 2012, confirmed as non-subcutaneous invasive extramammary Paget's disease by biopsy and underwent surgery. All patients were divided into two groups. Group ...
Hernigou Philippe P Orthopaedic Surgery, Hopital Henri Mondor, 51 Avenue du Maréchal de Lattre de Tassigny, 94010, Créteil, France, - - 2014
The purpose of this study was to evaluate the efficiency of biologic augmentation of rotator cuff repair with iliac crest bone marrow-derived mesenchymal stem cells (MSCs). The prevalence of healing and prevention of re-tears were correlated with the number of MSCs received at the tendon-to-bone interface. Forty-five patients in the ...
Lee Hye-Suk HS Division of Life and Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul, South - - 2014
Objective: The aim of this study was to investigate the prevalence and causes of early discontinuation and non-adherence to upfront and extended adjuvant letrozole therapy in breast cancer patients. Methods: Adherence was assessed using medical charts and longitudinal pharmacy records of 609 patients who initiated adjuvant letrozole between January 2002 ...
Vern-Gross Tamara Z TZ Department of Radiation Oncology, University of Florida Proton Therapy Institute, Jacksonville, Florida (T.Z.V.-G.); Department of Psychology, St. Jude Children's Research Hospital, Memphis, Tennessee (J.E.S.); Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee (A.B.); Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee (S.W., X.X.); Department of Radiological Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee - - 2014
A phase II trial of conformal radiotherapy (CRT) for pediatric high-grade glioma (HGG) was performed to evaluate disease control and late effects. Between July 1997 and January 2003, 34 pediatric patients (median age, 13.2 ± 6.7 years) with HGG were enrolled on an International Commission on Radiation Units and Measurements ...
Andrijević Derk B B University Clinical Centre 'Sestre milosrdnice', University Department of Ophthalmology, Zagreb, - - 2014
PurposeTo report a case series of three patients with bilateral uveal effusion syndrome (UES), treated conservatively with oral carbonic anhydrase inhibitors and topical prostaglandin analogues (PAs).MethodsThree patients with bilateral UES were treated with the same initial therapy. Topical PA latanoprost 0.005% and acetazolamide 250 mg were administered in order to reduce ...
Kim Hae Rim HR Department of Internal Medicine, Korea University College of - - 2014
This study compared the antiviral efficacy of telbivudine (TBV) and entecavir (ETV) in hepatitis B virus (HBV)-related liver cirrhosis. ETV is effective in the treatment of chronic HBV infections, even in patients with underlying cirrhosis. However, there is little information on the effect of TBV in chronic hepatitis B patients ...
Haak C S CS Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark; Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, - - 2014
Photodynamic therapy (PDT) is approved for selected nodular basal cell carcinomas (nBCC) but efficacy is reduced for large and thick tumours. Ablative fractional lasers (AFXL) facilitate uptake of methyl aminolevulinate (MAL) and may thus improve PDT outcome. Evaluate efficacy and safety of AFXL-mediated PDT (AFXL-PDT) compared to conventional PDT (PDT) ...
Cholongitas Evangelos E 4th Department of Internal Medicine, Medical School of Aristotle University, Hippokration General Hospital of Thessaloniki, - - 2014
New nucleos(t)ide agents (NAs) [entecavir (ETV) and tenofovir (TDF)] have made hepatitis B immunoglobulin (HBIG)-sparing protocols an attractive approach against hepatitis B virus (HBV) recurrence after liver transplantation (LT). Twenty eight patients transplanted for HBV cirrhosis in our centre were prospectively evaluated. After LT, each patient received HBIG (1,000IU IM/day ...
Kane Katherine K Division of Vascular Surgery, Baylor University Medical Center, Dallas, - - 2014
Endovenous laser ablation (EVLA) of the saphenous vein has become one of the preferred treatments for treating saphenous vein reflux that has resulted in symptomatic lower extremity venous insufficiency or varicose veins. This procedure was noted during initial reports to have a low incidence of postoperative thrombosis of the femoral ...
Wang Raymond Y RY Division of Metabolic Disorders, CHOC Children's, Orange, CA, USA. Electronic address: - - 2014
Treatment with intravenous enzyme replacement therapy and hematopoietic stem cell transplantation for mucopolysaccharidosis (MPS) type I does not address joint disease, resulting in persistent orthopedic complications and impaired quality of life. A proof-of-concept study was conducted to determine the safety, tolerability, and efficacy of intra-articular recombinant human iduronidase (IA-rhIDUA) enzyme ...
Kolek Matthew J MJ Department of Medicine, Vanderbilt University, Nashville, - - 2014
For many patients with atrial fibrillation, ventricular rate control with atrioventricular (AV) nodal blockers is considered first-line therapy, although response to treatment is highly variable. Using an extreme phenotype of failure of rate control necessitating AV nodal ablation and pacemaker implantation, we conducted a genome-wide association study (GWAS) to identify ...
Boucher Helen W HW From the Division of Infectious Diseases and Geographic Medicine, Tufts Medical Center and Tufts University School of Medicine, Boston (H.W.B.); the Department of Microbiology, Leeds Teaching Hospital and University of Leeds, Old Medical School, Leeds, United Kingdom (M.W.); Talbot Advisors, Anna Maria, FL (G.H.T.); Durata Therapeutics, Branford, CT (S.P., M.W.D.); and InClin, San Mateo, CA - - 2014
Background Dalbavancin, a lipoglycopeptide antibiotic agent that is active against gram-positive pathogens, has a long plasma half-life, allowing for once-weekly dosing. DISCOVER 1 and DISCOVER 2 were identically designed noninferiority trials of dalbavancin for the treatment of acute bacterial skin and skin-structure infection. Methods We randomly assigned patients to receive ...
Scott Dgi D Norfolk and Norwich University Hospital , Norwich , - - 2014
Objectives: To retrospectively evaluate continuation rates in patients with rheumatoid arthritis (RA) who failed to respond to or tolerate oral methotrexate (MTX) and were subsequently switched to subcutaneous MTX (SC MTX) in routine clinical practice. Method: We conducted a retrospective review of all patients with RA who had been prescribed ...
Brown Ashley L AL Department of Dermatology, University of Texas Southwestern-Austin, Austin, Texas, - - 2014
Primary focal hyperhidrosis is a common condition that negatively impacts quality of life for many pediatric patients and can be challenging to treat. Standard treatments for hyperhidrosis can be used with success in many patients, and newer therapies and techniques offer options that have demonstrated efficacy and safety. This review ...
Bose Abhishek A Cardiac Arrhythmia Service, Massachusetts General Hospital, 55 Fruit Street, Boston, Massachusetts, 02114, - - 2014
Cardiac valve surgery (CVS) has been implicated as a potential barrier to optimal response after cardiac resynchronization therapy (CRT) though prospective data regarding outcome remains limited. We sought to determine CRT response in patients with a prior history of CVS. We performed a retrospective analysis of a prospectively acquired cohort ...
Kukreja Kamlesh U KU Departments of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229. Electronic address: - - 2014
To evaluate the technical feasibility and safety of percutaneous endovascular thrombolysis for extremity deep venous thrombosis (DVT) in children < 24 months old. A retrospective chart review of a clinical and imaging database was performed for pediatric patients who underwent endovascular therapy for DVT between January 2010 and July 2013. ...
Archdeacon Michael T MT Department of Orthopaedic Surgery, University of Cincinnati, PO Box 670212, Cincinnati, OH, 45267-0212, USA, - - 2014
Prophylactic approaches to prevent heterotopic ossification after acetabular fracture surgery have included indomethacin and/or single-dose external beam radiation therapy administered after surgery. Although preoperative radiation has been used for heterotopic ossification prophylaxis in the THA population, to our knowledge, no studies have compared preoperative and postoperative radiation therapy in the ...
Yap Sing-Chien SC Department of Cardiology, Erasmus Medical Center, Rotterdam, The - - 2014
It is not clear whether patients who received an implantable cardioverter-defibrillator (ICD) for primary prevention should undergo device replacement if they never experienced an appropriate ICD therapy during the first generator longevity. This study evaluated the incidence and predictors of appropriate ICD therapy after device replacement in this specific population. ...
Al-Khatib Sana M - - 2014
The comparative effectiveness of treatments for atrial fibrillation (AF) is uncertain. To evaluate the comparative effectiveness of rate- and rhythm-control therapies. English-language studies in PubMed, EMBASE, and the Cochrane Database of Systematic Reviews between January 2000 and November 2013. Two reviewers independently screened citations to identify comparative studies that assessed ...
Palma Juan Carlos JC a Adjunct Professor, Department of Orthodontics, Faculty of Odontology, University Complutense, Madrid, - - 2014
Objective: To analyze the long-term stability of rapid maxillary expansion (RME) and protraction from chincup therapy in girls with Class III malocclusion. Materials and Methods: Twenty-two girls (mean age  =  9.1 ± 0.6 years) with Class III malocclusion were treated with combined RME and protraction from a chincup, followed by fixed ...
Xin Wei W Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, No. 2 Anzhen Road, Chaoyang District, Beijing, 100029, - - 2014
The role of B-type natriuretic peptide (BNP) in the management of patients with chronic heart failure (CHF) was uncertain. The aim of this meta-analysis was to comprehensively evaluate the effect of BNP-guided therapy in CHF. Relevant randomized controlled trials were identified by searching of Pubmed, Embase and the Cochrane Library ...
Washam Jeffrey B JB Duke Heart Center, Duke University Medical Center, DUMC 3943, Durham, NC, 27710, USA, - - 2014
Currently, there is a lack of consensus among guidelines for the postdischarge treatment of patients presenting with acute coronary syndrome (ACS) who have a long-term indication for anticoagulation. We conducted a systematic review comparing the safety and effectiveness of dual antiplatelet therapy (DAPT) and triple therapy (TT; defined as DAPT ...
Srivastava Rajeshwar N RN Department of Orthopaedic Surgery, King George's Medical University (KGMU), Lucknow, - - 2014
The conventional methods of treatment of pressure ulcers (PUs) by serial debridement and daily dressings require prolonged hospitalisation, associated with considerable morbidity. There is, however, recent evidence to suggest that negative pressure wound therapy (NPWT) accelerates healing. The commercial devices for NPWT are costly, cumbersome, and electricity dependent. We compared ...
Jayant Kumar K Department of Urology, Sudha Hospital and Medical Research Centre, Kota, Rajasthan, - - 2014
To compare the efficacy of tamsulosin versus tamsulosin plus tadalafil as medical expulsive therapy for lower ureteric stones. Between January 2013 and December 2013, 244 patients presenting with distal ureteric stones (size 5-10 mm) were randomized equally to tamsulosin (group A) or tamsulosin plus tadalafil (group B). Therapy was given for ...
McCarty Morgan M Dermatology Residency Program, Saint Joseph Mercy Health System, Ann Arbor, - - 2014
The twin goals of long-term disease control and minimizing toxicities related to immunosuppression necessitate efforts to find effective steroid-sparing agents in the management of patients with autoimmune bullous diseases. Pemphigus especially requires a long view, because the disease can persist throughout a patient's lifetime, yet few clinical trial reports exist ...
Rodríguez-Pardo D D Infectious Diseases Division, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, - - 2014
Catheter-related bacteraemia (CRB) is a cause of death in hospitalized patients, and parenteral nutrition (PN) is a risk factor. We aim to describe the prognosis of PN-CRB and the impact of catheter extraction within 48h from bacteraemia. All consecutive hospitalized adult patients with CRB (2007-2012) were prospectively enrolled. Factors associated ...
Smith Matthew R MR Liver Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, - - 2014
Endoscopic human thrombin injection appears to be a technically simple and efficacious alternative to tissue adhesives with fewer complications; however, data remain limited. We analysed our experience using endoscopic human thrombin injection for gastric varices in a tertiary referral liver unit. Thirty patients received thrombin injection for gastric varices between ...
Battaglia Alex A *Department of Otolaryngology, Head and Neck Surgery, Southern California Permanente Medical Group, San Diego; and †Department of Research and Evaluation, Regional Offices of Southern California Permanente Medical Group, Pasadena, California, - - 2014
To compare combination therapy (high-dose prednisone taper (HDPT) + intratympanic dexamethasone (IT-Dex)) hearing recovery results in ISSNHL patients with those treated with HDPT alone. Prospective, multicentered trial. Tertiary referral center. Eighty ISSNHL patients with class C or D hearing. Eighty qualifying patients were treated with IT-Dex (10 mg/ml) every week ...
Ruddy Kathryn J KJ Department of Oncology, Mayo Clinic, Rochester, MN. Electronic address: - - 2014
In premenopausal women with breast cancer, standard adjuvant endocrine therapy has been 5 years of tamoxifen. This study sought to investigate the safety and feasibility of treating patients who remain premenopausal after adjuvant tamoxifen with gonadotropin-releasing hormone agonist (GnRH-a) concurrent with an aromatase inhibitor, mimicking the strategy that has proven ...
Razavi Mahmood K MK St Joseph Hospital Heart & Vascular Center, 1140 West La Veta Ave, Suite 850, Orange, CA, 92868, USA, - - 2014
The basic treatment of deep vein thrombosis (DVT) over the past several decades has consisted of anticoagulation only, with inferior vena cava filtration for those who either failed or could not tolerate anticoagulation. Until recently no randomized trials had studied the efficacy of thrombolysis in DVT despite advances in techniques ...
Hanson Neil A NA From the *Department of Anesthesiology, Virginia Mason Medical Center; †Department of Anesthesiology, Physicians Anesthesia Service, Seattle, Washington; and ‡Axio Research, Seattle, - - 2014
Adductor canal blocks have shown promise in reducing postoperative pain in total knee arthroplasty patients. No randomized, controlled studies, however, evaluate the opioid-sparing benefits of a continuous 0.2% ropivacaine infusion at the adductor canal. We hypothesized that a continuous adductor canal block would decrease postoperative opioid consumption. Eighty subjects presenting ...
Mancini Nicasio N Laboratory of Microbiology and Virology, University "Vita-Salute" San Raffaele, Milan, - - 2014
We evaluated the costs and clinical outcomes of episodes of suspected sepsis in hematological patients. A propensity score-matched study was planned, comparing a retrospective cohort managed with standard assays and a prospective cohort managed with the addition of a molecular assay. Diagnostic procedures and therapy were considered as costs variables. ...
Grauhan Onnen O Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, - - 2014
Skin breakdown and infiltration of skin flora are key causative elements in poststernotomy wound infections. We hypothesised that surgical incision management (SIM) using negative pressure wound therapy over closed surgical incisions for 6-7 days would reduce wound infections in a comprehensive poststernotomy patient population. 'All comers' undergoing median sternotomy at our ...
Toker Serdar S Meram Faculty of Medicine, Department of Orthopaedic Surgery, Konya Selcuk University, Konya, - - 2014
Nonadherence to postoperative therapy protocols can adversely affect the outcome after flexor tendon surgery. In this study, we hypothesize that patients with partial or no insurance coverage for their aftercare are less likely to attend postoperative therapy sessions and have a higher incidence of a poorer outcome than those who ...
Hackshaw Michelle D MD 5 Crescent Dr., Philadelphia, PA 19112. - - 2014
Pazopanib is an oral tyrosine kinase inhibitor with demonstrated efficacy and tolerability in patients with advanced renal cell carcinoma (RCC). To examine pazopanib persistence and compliance (adherence) and other drug utilization patterns in both treatment-naïve (first-line) patients and those previously treated with RCC therapy in the real-world setting. Key factors ...
Brain Matthew J MJ School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia. - - 2014
The effectiveness of continuous renal replacement therapy (CRRT) increases when unplanned circuit failure is prevented. Adequate anticoagulation is an important component. Although heparin is the predominating anticoagulant, calcium chelation with citrate is an alternative, but systemic calcium monitoring and supplementation increase the complexity of CRRT. We assessed efficacy and safety ...
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