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Results 151 - 200 of 4748
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Loustaud-Ratti Véronique V Service d'Hépato-gastroentérologie, CHU de Limoges, 2, avenue Martin-Luther-King, 87042, Limoges, France; Inserm UMR 1092, Faculté de médecine de Limoges, Université de Limoges, Limoges, - - 2014
Renal toxicity of first generation protease inhibitors (PIs) was not a safety signal in phase III clinical trials, but was recently reported in studies. It appeared important to determine the clinical significance of these findings. We retrospectively analyzed 101 HCV patients receiving triple therapy with telaprevir (n=36) or boceprevir (n=26) ...
Dong Jun J Department of Medical Imaging and Image Guided Therapy, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, East Dong Feng Road 651, Guangzhou, 510060, Guangdong, People's Republic of - - 2014
The objective of this study was to assess the clinical efficacy of genetically engineered recombinant human adenovirus type 5 (rhAd5) plus transcatheter arterial chemoembolization in patients with unresectable hepatocellular carcinoma (HCC). Data from two groups of patients with unresectable HCC were retrospectively reviewed. One group included 149 patients treated with ...
Viers B R BR Department of Urology, Mayo Clinic, Rochester, - - 2014
Despite global concerns for antibiotic related complications, the duration of antibiotic therapy at time of percutaneous nephrolithotomy (PCNL) varies based upon individual physician practice. Herein, we evaluate perioperative antibiotic related complications among patients receiving extended antimicrobial therapy at PCNL. We reviewed 227 consecutive patients undergoing PCNL from 2009-2013. Patients with ...
Peng Ke K Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, - - 2014
Objective: To evaluate the influence of stroke volume variation (SVV)-based goal-directed therapy (GDT) on splanchnic organ functions and postoperative complications in orthopedic patients. Subjects and Methods: Eighty patients scheduled for major orthopedic surgery under general anesthesia were randomly allocated to one of two equal groups to receive either intraoperative volume ...
Alexopoulos D D Dimitrios Alexopoulos, MD, FACC, FESC, Cardiology Department, Patras University Hospital, Rion 26500, Patras, Greece, Tel/Fax: +30 2610992941, E-mail: - - 2014
Platelet reactivity (PR) and bleeding events following therapy with ticagrelor vs prasugrel have not been adequately studied. We aimed to compare PR and bleeding events in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) while on ticagrelor vs prasugrel for one month. Consecutive patients who were discharged ...
Lee Jung Won JW Department of Internal Medicine, Seoul National University Bundang Hospital , Seongnam, Gyeonggi-do , - - 2014
Abstract Objective. The eradication rate of 10-day sequential therapy for Helicobacter pylori (H. pylori) infection was not satisfactory in Korea, probably due to antibiotic resistance. To compare the treatment efficacy of 15-day and 10-day sequential therapy of conventional 7-day proton pump inhibitor (PPI) triple therapy for the treatment of H. ...
García Seara Javier J Cardiology Department, Arrhythmia Unit, Clinical University Hospital of Santiago de Compostela, Spain. Electronic address: - - 2014
To determine the long-term effectiveness of hybrid therapy in the control of atrial fibrillation (AF) as well as the differences in clinical outcomes between patients with antiarrhythmic drug atrial flutter (AAD-AFl), those with coexistent AFl and AF, and isolated AFl. Four hundred eight patients who consecutively underwent cavotricuspid isthmus (CTI) ...
Gupta Ankur A Department of Cardiology, Post Graduate Institute of Medical Education and Research, Chandigarh, - - 2014
Several key clinical questions, such as which patients with dilated cardiomyopathy (DC) will recover, how many will relapse, when will they relapse, and predictors of relapse, have sparse data. The present study examines the frequency and predictors of recovery and relapse in patients with DC. One hundred eighty-eight patients of ...
Kim Young-Sun YS 1 Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong, Gangnam-gu, Seoul 135-710, - - 2014
OBJECTIVE. The purposes of this study were to assess the widths of the intercostal spaces of the right inferior human rib cage through which high-intensity focused ultrasound therapy would be applied for treating liver cancer and to elucidate the demographic factors associated with intercostal space width. SUBJECTS AND METHODS. From ...
Katayama Kou K Katayama Orthopaedic Rheumatology Clinic , Asahikawa , - - 2014
Objective. We retrospectively investigated the inhibitory effect on radiographic joint damage (RJD) for non-biological disease-modifying antirheumatic drug (non-bioDMARD) monotherapy or methotrexate (MTX) combination therapy for rheumatoid arthritis (RA) in the disease activity score with 28 joint counts with erythrocyte sedimentation rate (DAS28) remission. Methods. Eighty-four patients (55 cases of monotherapy, ...
Chen Xuefu X Department of Infection, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, - - 2014
The present study compared the efficacy of standard and extended durations of PEG-IFNα-2a monotherapy for treatment of HBeAg-negative Chinese patients with chronic hepatitis B. Patients were randomized to receive standard therapy (n = 38; 48 weeks treatment) or extended therapy (n = 42; 72 weeks treatment). Extended therapy resulted in a significantly higher HBV ...
Ali Syed Shahzad SS Department of Physiotherapy, Dow University of Health Sciences, Karachi, - - 2014
To evaluate the effectiveness of Manual Therapy in comparison to Electrophysical agents in Knee Osteoarthritis. Total 50 patients with knee osteoarthritis were recruited from OPD of orthopedics civil hospital and Institute Of Physical Medicine & Rehabilitation, Dow University of Health Sciences Karachi. All those patients who fulfilled inclusion criteria were ...
Moodie Marj M Deakin Health Economics, Faculty of Health, Deakin University, Burwood, Australia. Electronic address: - - 2014
To determine whether bronchoalveolar lavage (BAL)-directed therapy for infants and young children with cystic fibrosis (CF), rather than standard therapy, was justified on the grounds of a decrease in average costs and whether the use of BAL reduced treatment costs associated with hospital admissions. Costs were assessed in a randomized ...
Kaya Cihan C Clinic of Obstetrics and Gynecology, Van Özalp State Hospital, Van, Turkey. Electronic address: - - 2014
To investigate the effect of enoxaparin on ovarian reserve and serum antimüllerian hormone (AMH) levels in a rat ovarian torsion model. Experimental study. Experimental surgery laboratory in a training and research hospital. Fourteen female Wistar Hannover rats. 1) Control group received no special treatment other than abdominal exposure; 2) detorsion-only ...
Nicol Noreen Heer NH College of Nursing, University of Colorado, Aurora, Colo; Department of Nursing, Children's Hospital Colorado, Aurora, Colo. Electronic address: - - 2014
Atopic dermatitis (AD) is the most common chronic, relapsing inflammatory skin disease of children and is a global public health problem. National and international AD guidelines address AD care in a stepwise fashion. Wet wrap therapy (WWT) is a therapeutic intervention for moderate-to-severe AD. This cohort study evaluated the effectiveness ...
Campbell Noreen N TCS Systems, North Saanich, BC, Canada; email: - - 2014
Maggot debridement is the deliberate use of larvae known to consume only necrotic tissue. A retrospective quality improvement analysis of maggot debridement therapy (MDT) was conducted among patients with devitalized tissue or gangrene attending a Canadian foot and leg ulcer clinic who received MDT between January 2001 and June 2006. ...
Sauerhammer Tina M TM Washington, D.C.; and Boston, Mass. From the Division of Plastic and Reconstructive Surgery, Children's National Medical Center; and the Department of Neurological Surgery, Children's Hospital Boston, Harvard Medical - - 2014
The combination of endoscope-assisted suturectomy and postoperative helmet therapy has been advocated to treat unilateral coronal synostosis. However, surgical outcomes can vary. One possible explanation for this inconsistency is early closure of the craniectomy gap. The authors examined short-term postoperative patency of the craniectomy gap and its relationship to phenotypic ...
Yim Elizabeth E Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, - - 2014
Limitation of ankle movement may contribute to calf muscle pump failure, which is thought to contribute to venous leg ulcer formation, which affects nearly 1 million Americans. We therefore wished to study ankle movement in patients with venous leg ulcers and its effect on healing. Using goniometry, we measured baseline ...
Rovner Eric E Department of Urology, Medical University of South Carolina, Charleston, South Carolina, - - 2014
Candidates for onabotulinumtoxinA are generally patients with overactive bladder (OAB) or neurogenic detrusor overactivity (NDO) whose disease is inadequately controlled with behavioral therapy and oral medication. All patients must be willing and able to perform clean intermittent catheterization (CIC). Before the decision to administer onabotulinumtoxinA is made, the clinician should ...
Shan Weiwei W Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China. ; Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, - - 2014
To compare the efficacy of metformin plus megestrol acetate (MA) with that of MA alone for treating endometrial atypical hyperplasia (EAH). This pilot study included 16 EAH patients who met at least one metabolic syndrome (MS) criterion and received either adjunctive metformin plus MA (MET group) or MA monotherapy (MA ...
Hong Keun-Sik KS Department of Neurology, Stroke Center, Ilsan Paik Hospital, Inje University, Goyang, - - 2014
Dual antiplatelet therapy simultaneously blocks different platelet activation pathways and might thus be more potent at inhibiting platelet activation and more effective at reducing major ischemic vascular events compared to antiplatelet monotherapy. Aspirin plus clopidogrel dual therapy is now the standard therapy for patients with acute coronary syndrome and for ...
Del Rosso James Q JQ Clinical Professor (Dermatology), Adjunct Faculty, Touro University College of Osteopathic Medicine, Henderson, Nevada and Private Practice, Dermatology and Cutaneous Surgery/Mohs Micrographic Surgery and Las Vegas Skin & Cancer Clinic/West Dermatology Group, Henderson and Las Vegas, - - 2014
Onychomycosis is a common infection of the nail unit that is usually caused by a dermatophyte (tinea unguium) and most frequently affects toenails in adults. In most cases, onychomycosis is associated with limited treatment options that are effective in achieving complete clearance in many cases. In addition, recurrence rates are ...
Zaidat O O Professor of Neurology, Neurosurgery, and Radiology, Medical College of Wisconsin, Milwaukee, WI, - - 2014
The infarct core has been theorised to be an important indicator for treatment success from endovascular intervention in acute ischemic stroke from large vessel proximal occlusion. The objective of this study was to determine the extent to which it contributes to the number of patients needed to treat (NNT) to ...
Delgado Almandoz J J Interventional Neuroradiology, Abbott Northwestern Hospital, Minneapolis, MN, - - 2014
Recent studies have examined the variability in response to clopidogrel therapy in patients undergoing endovascular treatment of unruptured cerebral aneurysms; however, no study has systematically assessed patient response to aspirin therapy in this patient population. This study aims to determine the initial response to aspirin therapy in patients undergoing endovascular ...
Massari F F Division Neuroimaging and Intervention (NII), Department of Radiology, University of Massachusetts, Worcester, MA, - - 2014
A new option in the treatment of large and complex intracranial aneurysms centerd along the cavernous/intradural segment of the ICA, proximal to the PCom artery, includes the utilization of flow-diverter devices. Intracranial stent/ flow diverter deployment in the treatment of aneurysm usually requires the administration of dual antiplatelet therapy for ...
Asayama-Kosaka Sachiko S Department of Dermatology, Nippon Medical School, - - 2014
Photodynamic therapy with aminolevulinic acid (ALA-PDT) is effective therapy for acne vulgaris; however, relatively strong side effects limit its wide usage. We have previously demonstrated that ALA-induced protoporphyrin IX distribution with lower concentrations and shorter contact time of ALA resulted in focused damage in sebaceous glands in vivo. We have ...
Mozdzanowski Christopher - - 2014
Otic barotrauma (OBT) is an adverse event seen in patients receiving hyperbaric oxygen (HBO2) therapy. After encountering a case of painless tympanic perforation during HBO2 therapy of a diabetic patient with the diagnosis of neuropathic Wagner Grade III foot ulcer, we hypothesized that peripheral neuropathy of the lower extremity may ...
Kim Ki Bae KB Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, - - 2014
Endoscopy for acute nonvariceal upper gastrointestinal bleeding plays an important role in primary diagnosis and management, particularly with respect to identification of high-risk stigmata lesions and to providing endoscopic hemostasis to reduce the risk of rebleeding and mortality. Early endoscopy, defined as endoscopy within the first 24 hours after presentation, ...
Cha Hyun-Kyu HK Department of Physical Therapy, College of Kyungbuk, Republic of - - 2014
[Purpose] The purpose of the study was to determine the effects of a sciatic nerve mobilization technique on improvement of lower limb function in patient with poststroke hemiparesis. [Subjects] Twenty- two stroke patients participated in this study. [Methods] They were randomly selected based on selection criteria and divided into two ...
Lee Soyoung S Department of Physical Therapy, Sahmyook University, Republic of - - 2014
[Purpose] The purpose of this study was to investigate the changes in pain, dysfunction, and grip strength of patients with acute lateral epicondylitis and to suggest the appropriate treatment frequency and period. [Subjects] The subjects were divided into three: 2 days per week group (n=12), 3 days per week group ...
Kang Jeong Il JI Department of Physical Therapy, Sehan University, Republic of - - 2014
[Purpose] We investigated the effect of low-intensity pulsed ultrasound and cryotherapy on joint function recovery and C-reactive protein (CRP) levels of patients with total knee replacement. [Subjects] Forty-six patients with total knee replacement were recruited and allocated to either low-intensity pulsed ultrasound therapy (n=15), cryotherapy (n=15), or a combination of ...
Yassin Mohamed A MA Department of Hematology, Hamad Medical Center, Doha, - - 2014
Osteoporosis represents the second most common cause of endocrinopathy in patients with beta thalassemia major (BTM). Some drugs proved effective to reduce vertebral and non-vertebral fracture risk. Denosumab is a fully human monoclonal antibody to the receptor activator of nuclear factor kappa B ligand (RANKL), a member of the tumor ...
Kapoor Sameer S Department of Anesthesiology, Critical Care and Pain Management, Mahatma Gandhi University of Medical Science and Technology, Sitapura, Jaipur, Rajasthan, - - 2014
i-gel(®), a recently introduced supraglottic airway device (SAD) has been claimed to be an efficient supraglottic airway. It can also be used as a conduit for endotracheal intubation. However, LMA Fastrach(®) frequently used for this purpose; hence in this randomized study, success rate of blind tracheal intubation through two different ...
Fitzmaurice Gerard J GJ Department of Cardiothoracic Surgery, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland; Department of Anaesthetics, Intensive Care & Pain Medicine, School of Medicine, Cardiff University, Cardiff, Wales. Electronic address: - - 2014
Cardiac surgical patients often have associated comorbidities that can impede normal wound healing; however, statin therapy has the potential to improve this process through augmentation of the normal inflammatory response. Outcomes included a 30% earlier rate of wound epithelialization and an 80% greater wound-breaking strength combined with faster wound healing ...
Fernandes Ana Paula AP Department of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, São Paulo, - - 2014
This study aimed to compare the clinical and radiographic effectiveness of Low Level Laser Therapy in vital pulp of human primary teeth. Sixty mandibular primary molars of children aged between 5-9 years were assigned into four groups: Diluted Formocresol (FC), Calcium Hydroxide (CH), Low Level Laser Therapy (LLLT) and Calcium Hydroxide ...
Togsverd-Bo K K Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, - - 2014
Topical photodynamic therapy (PDT) for actinic keratoses (AK) is hampered by pain during illumination and inferior efficacy in organ-transplant recipients (OTR). We assessed ablative fractional laser (AFL)-assisted daylight photodynamic therapy (PDT) (AFL-dPDT) compared to daylight PDT (dPDT), conventional PDT (cPDT) and AFL alone (AFL) in field treatment of AK in ...
Gupta Gaurav G 1 Department of Medicine, Virginia Commonwealth University, Richmond, VA. 2 Department of Medicine, University of Cincinnati, Cincinnati, OH. 3 Department of Pathology, Johns Hopkins University, Baltimore, MD. 4 Department of Medicine, Johns Hopkins University, Baltimore, MD. 5 Department of Pharmacy, Johns Hopkins Hospital, Baltimore, MD. 6 Department of Surgery, Johns Hopkins University, Baltimore, MD. 7 Address correspondence to: Nada Alachkar, MD, Johns Hopkins University School of Medicine, 600 Wolfe Street, Brady 502, Baltimore, MD - - 2014
Although several strategies for treating early antibody-mediated rejection (AMR) in kidney transplants have been investigated, evidence on treatment of late AMR manifesting after 6 months is sparse. In this single-center series, we present data on 23 consecutive patients treated for late AMR. Late AMR was diagnosed using Banff 2007 criteria ...
Khandelwal P P Bone Marrow Transplant and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH. Electronic address: - - 2014
Therapy of refractory autoimmunity remains challenging. In this study, we evaluated the therapeutic effect of bortezomib, a proteasome inhibitor, by targeting plasma cells in seven patients, median age 9.9 years. Four doses of bortezomib were administered at a dose of 1 3.mg/m2 intravenously (n=6) or subcutaneously (n=1) every seventy-two hours. ...
Ion Daniela D Oral Medicine Department, Guy's and St. Thomas' NHS Foundation Trust, London, - - 2014
Acute graft-versus-host-disease (aGVHD) is a major complication of allogeneic hematopoietic stem cell transplantation (HSCT). The purpose of this study was to characterize the oral features associated with aGVHD. Patients who underwent HSCT between 1995 and 2010 and developed prominent oral aGVHD. Data was collected from patient medical records and analyzed ...
Yang Xi X *Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China; †Special Department of Hemangioma, Hospital of PLA General Political Department, Beijing, - - 2014
Lymphangioma circumscriptum (LC) is a type of microcystic lymphatic malformation involving the skin and mucosa that presents as translucent vesicles of varying size with a pink, red, or black hue. Lymphangioma circumscriptum causes not only cosmetic problems but also refractory rupture, infection, lymphorrhea, and bleeding. Various invasive methods, such as ...
Honda Shigeru S Department of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine, Kobe, - - 2014
Background: To compare the outcomes of photodynamic therapy (PDT) between two different angiographic subtypes of polypoidal choroidal vasculopathy (PCV). Methods: Ninety-three consecutive cases of PCV were classified into two phenotypes (42 type 1 and 51 type 2) according to the presence or absence of feeding vessels found on indocyanine green ...
Walsh Michael M Departments of Medicine and Clinical Epidemiology and Biostatistics, Population Health Research Institute, McMaster University and Population Health Research Institute, Hamilton, Ontario, Canada; - - 2014
Treatment with azathioprine within 3 months of remission induction with cyclophosphamide is a common treatment strategy for patients with ANCA-associated vasculitis. This study comprised patients undergoing long-term follow-up who were randomly allocated to azathioprine after 3-6 months or after 12 months of cyclophosphamide treatment.DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Patients from ...
Haider Ahmad A Private Urology Practice, Bremerhaven, - - 2014
Although there is no evidence that testosterone (T) therapy increases risk of prostate cancer (PCa), there is a paucity of long-term data. To determine whether incidence of PCa is increased in hypogonadal men receiving long-term T therapy. In three parallel, prospective, ongoing, cumulative registry studies, 1,023 hypogonadal men received T ...
Bhamra-Ariza Paul P Cardiology Dept, St Vincent's Hospital, Victoria St, Darlinghurst, NSW 2010, - - 2014
Mitral regurgitation is the most common valve abnormality worldwide and its prevalence is expected to increase in the future due to aging of the population. Percutaneous mitral valve repair therapies may offer an opportunity to treat severe MR in the elderly or other high-risk groups who would otherwise be ineligible ...
May Teresa L TL Division of Pulmonary and Critical Care Medicine, Maine Medical Center, 22 Bramhall St, Portland, ME, 04102, USA, - - 2014
Sedation and analgesia regimens during targeted temperature management (TTM), after cardiac arrest varies widely, are poorly described in the literature and may have a negative impact on outcome. Since implementing TTM in 2005, we have used moderate-dose sedation and describe our experience with this approach. In this retrospective review, we ...
Almond L M LM Department of Upper Gastrointestinal Surgery, Gloucestershire Royal Hospital, - - 2014
The optimal management of patients with Barrett's-associated low-grade dysplasia (LGD) is unclear. The objective of this study was to identify systematically all reports of endoscopic treatment of LGD, and to assess outcomes in terms of disease progression, eradication of dysplasia and intestinal metaplasia, and complication rates. A systematic review of ...
Raman Renukanth Patabi - - 2014
40 subjects with type 2 diabetes and moderate to severe CP were randomly distributed to groups receiving either NSPT or OHI. Periodontal parameters, glycosylated haemoglobin (HbA1c) and high-sensitivity C-reactive protein (hs-CRP) were evaluated at baseline, 2- and 3-months intervals. 40 subjects with type 2 diabetes and moderate to severe CP ...
Zhang Bin B Laser Plastic and Aesthetic Center, Liuhuaqiao Hospital, Guangzhou, - - 2014
Several studies suggest that vascular-acting photodynamic therapy (PDT) might be an alternative approach for treating port wine stain birthmarks (PWS) but the usefulness of PDT for pediatric patients has not been fully investigated. Study design: Medical records of pediatric patients (3 - 10 years old) with red and purple facial ...
Driul L L Clinic of Obstetrics and Gynecology, AOU 'SM della Misericordia' of Udine , Udine , - - 2014
The objective of this study was to compare the safety and efficacy of atosiban and ritodrine in the treatment of threatened preterm labour (TPL) and to analyse the predictive factors of preterm delivery. We retrospectively sampled data on 380 women hospitalised for TPL (24-35 weeks' gestation), in our clinic between ...
Coutin Julia V JV Department of Small Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Blacksburg, - - 2014
To compare cefazolin concentrations in biopsied tissue samples collected from surgically created wounds treated with negative pressure wound therapy to those collected from surgically created wounds treated with nonadherent dressings. Prospective, controlled, experimental study. Adult female spayed Beagles (n = 12). Full thickness cutaneous wounds were created on each antebrachium (n = 24). Immediately ...
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